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RdRp
Euk-VirHubei_permutotetra-like_virus_9
RdRp__YP_009337778__Hubei_permutotetra-like_virus_9__1923083
Identity
- Accession:
- YP_009337778 ↗
- Protein ID:
- RdRp
- Kingdom:
- euk
Quality
74.0
mean pLDDT
Cluster
View cluster (20 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 22-72_545-679
Domain cluster:
rep: RdRp__YP_009337318__Hubei_permutotetra-like_virus_6__1923080__D29-60_540-665
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF22260.2 best | Permu_RdRp_thumb | 101.5 | 3.70e-29 | 57.0% | 100.0% |
D2
high
residues 905-1002
Domain cluster:
representative
CATH (39)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4wyqB00 | 3.30.160.20 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › | 0.75 | 52.0 | 5.80e-01 | 77.6% | 92.0% |
| 2mdrA00 | 3.30.160.20 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › | 0.70 | 56.0 | 5.71e-01 | 86.7% | 87.2% |
| 1yqzA03 | 3.30.390.30 | Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › FAD/NAD-linked reductase, C-terminal dimerisation domain | 0.68 | 41.0 | 4.00e-01 | 81.6% | 54.6% |
| 2gvhB02 | 3.10.129.10 | Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase | 0.67 | 40.0 | 3.76e-01 | 83.7% | 48.7% |
| 2v1oB00 | 3.10.129.10 | Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase | 0.66 | 39.0 | 3.42e-01 | 83.7% | 38.5% |
| 2lrsA00 | 3.30.160.20 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › | 0.66 | 45.0 | 5.14e-01 | 70.4% | 97.2% |
| 1nhpA03 | 3.30.390.30 | Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › FAD/NAD-linked reductase, C-terminal dimerisation domain | 0.66 | 41.0 | 3.94e-01 | 81.6% | 54.0% |
| 2cduA03 | 3.30.390.30 | Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › FAD/NAD-linked reductase, C-terminal dimerisation domain | 0.66 | 41.0 | 3.92e-01 | 81.6% | 54.0% |
| 2bi0A02 | 3.10.129.10 | Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase | 0.65 | 39.0 | 3.44e-01 | 83.7% | 40.8% |
| 1gesA03 | 3.30.390.30 | Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › FAD/NAD-linked reductase, C-terminal dimerisation domain | 0.62 | 40.0 | 3.79e-01 | 80.6% | 55.8% |
| 3kh8B01 | 3.10.129.10 | Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase | 0.61 | 37.0 | 3.24e-01 | 82.7% | 37.7% |
| 2hboA01 | 3.10.129.10 | Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase | 0.61 | 35.0 | 3.19e-01 | 83.7% | 40.6% |
| 1pn2B01 | 3.10.129.10 | Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase | 0.59 | 38.0 | 3.32e-01 | 83.7% | 42.6% |
| 7sulB01 | 2.130.10.10 | Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase | 0.57 | 40.0 | 2.83e-01 | 73.5% | 29.3% |
| 3loyA02 | 3.10.450.40 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.57 | 42.0 | 4.03e-01 | 77.6% | 79.8% |
| 2wraA00 | 2.60.120.400 | Mainly Beta › Sandwich › Jelly Rolls › Calcium-mediated lectin | 0.56 | 43.0 | 4.06e-01 | 82.7% | 85.2% |
| 6kghA02 | 3.30.450.330 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › | 0.56 | 50.0 | 4.32e-01 | 100.0% | 74.7% |
| 3b7kB01 | 3.10.129.10 | Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase | 0.55 | 39.0 | 3.42e-01 | 71.4% | 65.7% |
| 3ugfB02 | 2.60.120.560 | Mainly Beta › Sandwich › Jelly Rolls › Exo-inulinase; domain 1 | 0.55 | 42.0 | 3.49e-01 | 82.7% | 67.8% |
| 5df7A02 | 3.40.710.10 | Alpha Beta › 3-Layer(aba) Sandwich › Beta-lactamase › DD-peptidase/beta-lactamase superfamily | 0.54 | 48.0 | 3.33e-01 | 100.0% | 88.9% |
| 1fx3B00 | 3.10.420.10 | Alpha Beta › Roll › Bacterial Protein-export protein SecB › SecB-like | 0.54 | 50.0 | 4.28e-01 | 100.0% | 69.8% |
| 5tfqA00 | 3.40.710.10 | Alpha Beta › 3-Layer(aba) Sandwich › Beta-lactamase › DD-peptidase/beta-lactamase superfamily | 0.54 | 49.0 | 3.52e-01 | 100.0% | 90.3% |
| 6izcA00 | 3.40.710.10 | Alpha Beta › 3-Layer(aba) Sandwich › Beta-lactamase › DD-peptidase/beta-lactamase superfamily | 0.54 | 49.0 | 3.57e-01 | 100.0% | 92.4% |
| 6pl6B01 | 3.40.710.10 | Alpha Beta › 3-Layer(aba) Sandwich › Beta-lactamase › DD-peptidase/beta-lactamase superfamily | 0.54 | 48.0 | 3.29e-01 | 100.0% | 90.1% |
| 3nqkA02 | 2.40.128.440 | Mainly Beta › Beta Barrel › Lipocalin › Uncharacterised protein PF14274, DUF4361 | 0.53 | 42.0 | 3.56e-01 | 83.7% | 90.6% |
| 1sr9A02 | 3.30.160.270 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Alpha-isopropylmalate synthase LeuA, regulatory domain | 0.53 | 43.0 | 3.76e-01 | 92.9% | 70.7% |
| 3eqvA02 | 3.30.450.330 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › | 0.53 | 48.0 | 4.31e-01 | 100.0% | 74.4% |
| 4jf6A00 | 3.40.710.10 | Alpha Beta › 3-Layer(aba) Sandwich › Beta-lactamase › DD-peptidase/beta-lactamase superfamily | 0.52 | 47.0 | 3.55e-01 | 100.0% | 92.5% |
| 2ebkA00 | 3.10.110.10 | Alpha Beta › Roll › Ubiquitin Conjugating Enzyme › Ubiquitin Conjugating Enzyme | 0.52 | 38.0 | 3.56e-01 | 77.6% | 79.7% |
| 3nwzB00 | 3.10.129.10 | Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase | 0.52 | 36.0 | 3.14e-01 | 71.4% | 90.7% |
| 1kiaA01 | 3.30.46.10 | Alpha Beta › 2-Layer Sandwich › Glycine N-methyltransferase; chain A, domain 1 › Glycine N-methyltransferase, chain A, domain 1 | 0.52 | 38.0 | 4.01e-01 | 77.6% | 98.8% |
| 1ukxA00 | 3.10.110.10 | Alpha Beta › Roll › Ubiquitin Conjugating Enzyme › Ubiquitin Conjugating Enzyme | 0.51 | 38.0 | 3.43e-01 | 78.6% | 75.2% |
| 2plqA00 | 3.60.110.10 | Alpha Beta › 4-Layer Sandwich › Nitrilase/N-carbamoyl-D-aminoacid amidohydrolase › Carbon-nitrogen hydrolase | 0.51 | 40.0 | 2.83e-01 | 86.7% | 59.7% |
| 4kc5C03 | 3.10.129.110 | Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Polyketide synthase dehydratase | 0.51 | 41.0 | 2.91e-01 | 86.7% | 82.2% |
| 1xkzC00 | 3.40.710.10 | Alpha Beta › 3-Layer(aba) Sandwich › Beta-lactamase › DD-peptidase/beta-lactamase superfamily | 0.51 | 46.0 | 3.42e-01 | 100.0% | 88.7% |
| 4gn2A00 | 3.40.710.10 | Alpha Beta › 3-Layer(aba) Sandwich › Beta-lactamase › DD-peptidase/beta-lactamase superfamily | 0.50 | 45.0 | 3.40e-01 | 100.0% | 97.5% |
| 2daxA01 | 3.10.110.10 | Alpha Beta › Roll › Ubiquitin Conjugating Enzyme › Ubiquitin Conjugating Enzyme | 0.50 | 37.0 | 3.32e-01 | 78.6% | 82.3% |
| 5o16B00 | 3.10.129.110 | Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Polyketide synthase dehydratase | 0.50 | 46.0 | 3.28e-01 | 99.0% | 55.5% |
| 3kg7B00 | 3.10.129.110 | Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Polyketide synthase dehydratase | 0.50 | 45.0 | 3.22e-01 | 99.0% | 56.1% |
ECOD (46)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3596299 | 330.1.1.0 ↗ | a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like | 0.74 | 56.0 | 5.48e-01 | 79.6% | 91.4% |
| 3710326 | 330.1.1.0 ↗ | a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like | 0.74 | 53.0 | 5.68e-01 | 79.6% | 87.1% |
| 3445028 | 330.1.1.0 ↗ | a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like | 0.74 | 55.0 | 5.96e-01 | 77.6% | 96.2% |
| 3704403 | 330.1.1.0 ↗ | a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like | 0.72 | 54.0 | 5.49e-01 | 77.6% | 92.6% |
| 3505181 | 330.1.1.5 ↗ | a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › DND1_DSRM | 0.72 | 54.0 | 5.88e-01 | 78.6% | 98.8% |
| 4444614 | 330.1.1.0 ↗ | a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like | 0.72 | 54.0 | 5.95e-01 | 78.6% | 96.2% |
| 4472716 | 330.1.1.3 ↗ | a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › Dicer_dimer | 0.70 | 52.0 | 4.68e-01 | 77.6% | 63.8% |
| 3481273 | 330.1.1.0 ↗ | a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like | 0.68 | 55.0 | 5.36e-01 | 84.7% | 80.0% |
| 3825504 | 330.1.1.5 ↗ | a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › DND1_DSRM | 0.68 | 50.0 | 5.25e-01 | 77.6% | 84.4% |
| 4936781 | 244.2.1.1 ↗ | a+b two layers › FAD-linked reductases, C-terminal domain-like › FAD/NAD-linked reduatases, dimerisation (C-terminal) domain › FAD/NAD-linked reduatases, dimerisation (C-terminal) domain › Pyr_redox_dim | 0.67 | 42.0 | 3.81e-01 | 81.6% | 47.7% |
| 3609908 | 330.1.1.0 ↗ | a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like | 0.66 | 51.0 | 4.90e-01 | 80.6% | 82.7% |
| 3939992 | 330.1.1.0 ↗ | a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like | 0.66 | 54.0 | 5.23e-01 | 87.8% | 85.5% |
| 5055184 | 295.1.1.0 ↗ | a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain | 0.66 | 45.0 | 4.81e-01 | 78.6% | 82.4% |
| 4982148 | 244.2.1.1 ↗ | a+b two layers › FAD-linked reductases, C-terminal domain-like › FAD/NAD-linked reduatases, dimerisation (C-terminal) domain › FAD/NAD-linked reduatases, dimerisation (C-terminal) domain › Pyr_redox_dim | 0.65 | 40.0 | 3.78e-01 | 81.6% | 50.0% |
| 3631773 | 222.1.1.4 ↗ | a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › 4HBT | 0.65 | 37.0 | 3.06e-01 | 83.7% | 30.9% |
| 5001433 | 244.2.1.1 ↗ | a+b two layers › FAD-linked reductases, C-terminal domain-like › FAD/NAD-linked reduatases, dimerisation (C-terminal) domain › FAD/NAD-linked reduatases, dimerisation (C-terminal) domain › Pyr_redox_dim | 0.65 | 41.0 | 3.67e-01 | 81.6% | 45.9% |
| 3283651 | 222.1.1.9 ↗ | a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › MaoC_dehydrat_N | 0.63 | 38.0 | 3.53e-01 | 83.7% | 46.4% |
| 3587843 | 244.2.1.1 ↗ | a+b two layers › FAD-linked reductases, C-terminal domain-like › FAD/NAD-linked reduatases, dimerisation (C-terminal) domain › FAD/NAD-linked reduatases, dimerisation (C-terminal) domain › Pyr_redox_dim | 0.63 | 41.0 | 3.73e-01 | 81.6% | 49.6% |
| 3785102 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.63 | 47.0 | 3.41e-01 | 100.0% | 26.9% |
| 3988052 | 244.2.1.1 ↗ | a+b two layers › FAD-linked reductases, C-terminal domain-like › FAD/NAD-linked reduatases, dimerisation (C-terminal) domain › FAD/NAD-linked reduatases, dimerisation (C-terminal) domain › Pyr_redox_dim | 0.63 | 39.0 | 3.63e-01 | 81.6% | 49.2% |
| 4873579 | 4019.1.1.3 ↗ | alpha complex topology › alpha-helical domain in beta-lactamase/transpeptidase-like proteins › alpha-helical domain in beta-lactamase/transpeptidase-like proteins › alpha-helical domain in beta-lactamase/transpeptidase-like proteins › Transpeptidase | 0.62 | 40.0 | 4.42e-01 | 83.7% | 83.3% |
| 2640602 | 222.1.1.4 ↗ | a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › 4HBT | 0.62 | 38.0 | 3.74e-01 | 86.7% | 56.0% |
| 3386467 | 7503.1.1.0 ↗ | a/b three-layered sandwiches › TolB, N-terminal domain › TolB, N-terminal domain › TolB, N-terminal domain | 0.61 | 54.0 | 4.76e-01 | 100.0% | 98.7% |
| 4945010 | 5.1.3.0 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed | 0.58 | 44.0 | 3.14e-01 | 81.6% | 45.5% |
| 3282536 | 330.4.1.1 ↗ | a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC | 0.58 | 41.0 | 4.41e-01 | 73.5% | 91.3% |
| 4954298 | 504.1.1.0 ↗ | a+b two layers › Bacterial protein-export protein SecB › Bacterial protein-export protein SecB › Bacterial protein-export protein SecB | 0.57 | 47.0 | 4.83e-01 | 100.0% | 92.6% |
| 4318546 | 504.1.1.1 ↗ | a+b two layers › Bacterial protein-export protein SecB › Bacterial protein-export protein SecB › Bacterial protein-export protein SecB › SecB | 0.56 | 51.0 | 4.59e-01 | 100.0% | 79.3% |
| 3991810 | 216.1.1.4 ↗ | a+b two layers › UBC-like › UBC-like › UBC-like › RWD | 0.56 | 41.0 | 3.61e-01 | 77.6% | 70.7% |
| 3973413 | 7503.1.1.0 ↗ | a/b three-layered sandwiches › TolB, N-terminal domain › TolB, N-terminal domain › TolB, N-terminal domain | 0.56 | 48.0 | 4.26e-01 | 100.0% | 97.4% |
| 4652220 | 223.3.1.3 ↗ | a+b three layers › Profilin-like › a+b domain in beta-lactamase/transpeptidase-like proteins › a+b domain in beta-lactamase/transpeptidase-like proteins › Transpeptidase | 0.56 | 50.0 | 3.45e-01 | 100.0% | 90.6% |
| 3410646 | 223.1.1.71 ↗ | a+b three layers › Profilin-like › sensor domains › sensor domains › VGCC_alpha2 | 0.56 | 38.0 | 2.83e-01 | 71.4% | 47.7% |
| 3993254 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.55 | 37.0 | 4.10e-01 | 75.5% | 85.0% |
| 3966462 | 223.3.1.3 ↗ | a+b three layers › Profilin-like › a+b domain in beta-lactamase/transpeptidase-like proteins › a+b domain in beta-lactamase/transpeptidase-like proteins › Transpeptidase | 0.55 | 49.0 | 3.37e-01 | 100.0% | 88.4% |
| 3589951 | 223.3.1.3 ↗ | a+b three layers › Profilin-like › a+b domain in beta-lactamase/transpeptidase-like proteins › a+b domain in beta-lactamase/transpeptidase-like proteins › Transpeptidase | 0.55 | 49.0 | 3.28e-01 | 100.0% | 91.2% |
| 3806226 | 708.1.1.1 ↗ | beta complex topology › ETN0001 domain-like › ETN0001 domain-like › NAC/WRKY/GCM/WOPR domain › NAM | 0.55 | 46.0 | 3.99e-01 | 95.9% | 80.6% |
| 3275455 | 4210.1.1.0 ↗ | a+b two layers › WGR domain › WGR domain › WGR domain | 0.53 | 45.0 | 4.25e-01 | 94.9% | 79.2% |
| 5068525 | 223.1.1.13 ↗ | a+b three layers › Profilin-like › sensor domains › sensor domains › PAS_3 | 0.53 | 36.0 | 3.25e-01 | 70.4% | 84.3% |
| 4024578 | 216.1.1.4 ↗ | a+b two layers › UBC-like › UBC-like › UBC-like › RWD | 0.52 | 38.0 | 3.29e-01 | 76.5% | 65.8% |
| 165196 | 216.1.1.4 ↗ | a+b two layers › UBC-like › UBC-like › UBC-like › RWD | 0.52 | 38.0 | 3.56e-01 | 77.6% | 79.7% |
| 4681169 | 223.3.1.0 ↗ | a+b three layers › Profilin-like › a+b domain in beta-lactamase/transpeptidase-like proteins › a+b domain in beta-lactamase/transpeptidase-like proteins | 0.52 | 46.0 | 3.08e-01 | 100.0% | 70.5% |
| 4670273 | 868.1.1.8 ↗ | a+b complex topology › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › SLS1_C | 0.51 | 39.0 | 2.98e-01 | 82.7% | 82.9% |
| 4986643 | 2484.1.1.148 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_5 | 0.51 | 45.0 | 3.07e-01 | 100.0% | 27.8% |
| 2082805 | 243.3.1.1 ↗ | a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin › Cystatin | 0.51 | 34.0 | 3.58e-01 | 70.4% | 80.4% |
| 4999273 | 223.1.1.13 ↗ | a+b three layers › Profilin-like › sensor domains › sensor domains › PAS_3 | 0.51 | 35.0 | 2.20e-01 | 73.5% | 58.0% |
| 4003463 | 220.1.1.168 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › Tmpp129 | 0.50 | 41.0 | 3.87e-01 | 95.9% | 71.2% |
| 4985869 | 283.2.1.0 ↗ | a+b duplicates or obligate multimers › Creatinase/aminopeptidase-like › gpW/gp25-like › gpW/gp25-like | 0.50 | 36.0 | 3.82e-01 | 75.5% | 98.9% |
D3
high
residues 1042-1115
D4
medium
residues 11-21_92-114_211-329_414-453
D5
medium
residues 115-179
Domain cluster:
representative
D6
medium
residues 180-210_384-413
Domain cluster:
representative
D7
medium
residues 330-383_454-544
Domain cluster:
rep: RdRp__YP_009337318__Hubei_permutotetra-like_virus_6__1923080__D328-384_485-539
D8
medium
residues 680-815
D9
medium
residues 816-899