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RdRp
Euk-VirWuhan_insect_virus_22
RdRp__YP_009346039__Wuhan_insect_virus_22__1923726
Identity
- Accession:
- YP_009346039 ↗
- Protein ID:
- RdRp
- Kingdom:
- euk
Quality
79.2
mean pLDDT
Cluster
View cluster (450 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 448-544
Domain cluster:
representative
CATH (37)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 6wb9201 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.66 | 46.0 | 3.24e-01 | 97.9% | 23.9% |
| 3qbmB00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.65 | 50.0 | 3.98e-01 | 82.5% | 76.6% |
| 3qwwA03 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.65 | 47.0 | 3.76e-01 | 95.9% | 38.7% |
| 1q6aA00 | 1.10.1240.30 | Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › KaiA/RbsU domain | 0.64 | 46.0 | 4.53e-01 | 77.3% | 78.5% |
| 2ondA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.63 | 53.0 | 3.71e-01 | 100.0% | 29.2% |
| 1wn0A00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.61 | 41.0 | 3.72e-01 | 82.5% | 51.1% |
| 7qihA01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.61 | 40.0 | 3.97e-01 | 96.9% | 63.4% |
| 2j4bB00 | 1.25.40.500 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › TFIID subunit TAF5, NTD2 domain | 0.61 | 46.0 | 4.18e-01 | 96.9% | 59.4% |
| 3ccyA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.60 | 46.0 | 4.02e-01 | 80.4% | 78.2% |
| 3f1bA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.60 | 46.0 | 3.77e-01 | 82.5% | 78.1% |
| 3dcfA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.59 | 45.0 | 3.97e-01 | 80.4% | 78.2% |
| 3i3nA02 | 1.25.40.420 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.59 | 42.0 | 4.15e-01 | 96.9% | 68.9% |
| 3k1rA01 | 1.20.1160.20 | Mainly Alpha › Up-down Bundle › Paired amphipathic helix 2 (pah2 repeat) › | 0.58 | 39.0 | 4.13e-01 | 91.8% | 80.2% |
| 5hayA02 | 1.25.40.440 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Nucleoporin, helical domain, central subdomain | 0.58 | 40.0 | 4.28e-01 | 94.8% | 86.1% |
| 4b94A00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.58 | 45.0 | 3.99e-01 | 97.9% | 56.7% |
| 4kwaB00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.58 | 44.0 | 3.62e-01 | 82.5% | 77.1% |
| 3uumA00 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.57 | 44.0 | 4.10e-01 | 81.4% | 78.7% |
| 1hciA04 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.57 | 45.0 | 4.27e-01 | 83.5% | 83.3% |
| 4mo7A02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.56 | 46.0 | 4.13e-01 | 90.7% | 90.8% |
| 2f07B00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.56 | 44.0 | 3.58e-01 | 86.6% | 91.3% |
| 1w99A01 | 1.20.190.10 | Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain | 0.56 | 49.0 | 4.12e-01 | 100.0% | 71.1% |
| 2qr4A01 | 1.20.140.70 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Oligopeptidase f, N-terminal domain | 0.55 | 47.0 | 4.07e-01 | 94.8% | 76.9% |
| 1t98A01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.55 | 37.0 | 3.93e-01 | 71.1% | 80.5% |
| 4w8pA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.54 | 43.0 | 3.89e-01 | 83.5% | 70.0% |
| 3pe0A01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.54 | 42.0 | 4.16e-01 | 82.5% | 92.1% |
| 2lqgA00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.54 | 41.0 | 3.62e-01 | 79.4% | 60.1% |
| 2dg8D00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.53 | 40.0 | 3.43e-01 | 83.5% | 64.7% |
| 2gfnA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.53 | 47.0 | 3.78e-01 | 100.0% | 53.6% |
| 1t33A02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.52 | 39.0 | 3.39e-01 | 80.4% | 75.9% |
| 1cunA01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.52 | 40.0 | 4.02e-01 | 83.5% | 94.1% |
| 5wp3B00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.52 | 40.0 | 3.97e-01 | 82.5% | 87.3% |
| 3ce2A01 | 1.20.140.70 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Oligopeptidase f, N-terminal domain | 0.52 | 43.0 | 3.80e-01 | 94.8% | 72.7% |
| 2e9xD01 | 1.20.58.1030 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.52 | 42.0 | 3.82e-01 | 91.8% | 74.5% |
| 4oydB00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.52 | 39.0 | 3.74e-01 | 82.5% | 87.2% |
| 2ibdA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.51 | 38.0 | 3.47e-01 | 83.5% | 91.8% |
| 8ek4A01 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.50 | 39.0 | 3.51e-01 | 82.5% | 83.5% |
| 4kb2A01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.50 | 38.0 | 3.73e-01 | 82.5% | 88.1% |
ECOD (28)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4403090 | 191.1.1.50 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › SlmA-like_C | 0.63 | 50.0 | 4.36e-01 | 84.5% | 86.2% |
| 429313 | 109.4.1.288 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Nro1_C | 0.61 | 47.0 | 4.10e-01 | 96.9% | 53.7% |
| 3799103 | 4146.1.1.0 ↗ | alpha bundles › YqgQ-like › YqgQ-like › YqgQ-like | 0.61 | 46.0 | 4.18e-01 | 97.9% | 59.2% |
| 3925111 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.61 | 50.0 | 3.94e-01 | 99.0% | 42.9% |
| 3257076 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.59 | 46.0 | 4.02e-01 | 93.8% | 55.2% |
| 2392079 | 109.3.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat | 0.59 | 41.0 | 3.04e-01 | 83.5% | 27.0% |
| 3271585 | 109.4.1.1958 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF28615 | 0.59 | 48.0 | 3.46e-01 | 99.0% | 30.7% |
| 3800773 | 109.27.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › BACK domain › BACK domain | 0.59 | 47.0 | 4.58e-01 | 86.6% | 91.4% |
| 3974601 | 601.3.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain | 0.57 | 40.0 | 3.89e-01 | 83.5% | 64.5% |
| 3540152 | 509.1.1.8 ↗ | alpha bundles › PAH2 domain › PAH2 domain › PAH2 domain › ZSWIM4-8_C | 0.56 | 38.0 | 3.69e-01 | 76.3% | 59.6% |
| 4645242 | 191.1.1.26 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › TetR_C_24 | 0.56 | 46.0 | 4.10e-01 | 90.7% | 92.4% |
| 4424244 | 109.4.1.923 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › AEP1 | 0.56 | 45.0 | 4.11e-01 | 100.0% | 65.4% |
| 3616669 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.55 | 42.0 | 4.01e-01 | 82.5% | 86.1% |
| 3746634 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.54 | 42.0 | 3.91e-01 | 83.5% | 76.0% |
| 3574755 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.54 | 42.0 | 4.09e-01 | 83.5% | 84.5% |
| 3349197 | 109.4.1.192 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8 | 0.54 | 47.0 | 3.58e-01 | 99.0% | 47.9% |
| 3921635 | 603.2.1.0 ↗ | alpha bundles › STAT-like › STAT › STAT | 0.54 | 42.0 | 3.33e-01 | 82.5% | 48.9% |
| 3991215 | 109.4.1.649 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › DUF4807 | 0.53 | 42.0 | 3.52e-01 | 100.0% | 48.0% |
| 3578909 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.53 | 41.0 | 4.02e-01 | 82.5% | 88.6% |
| 3474664 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.53 | 47.0 | 3.90e-01 | 99.0% | 66.5% |
| 3251068 | 109.3.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat | 0.53 | 44.0 | 3.34e-01 | 91.8% | 39.6% |
| 3941051 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.52 | 46.0 | 3.89e-01 | 100.0% | 70.6% |
| 3297644 | 101.1.1.148 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › EPL1 | 0.52 | 40.0 | 3.66e-01 | 82.5% | 72.3% |
| 3178195 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.52 | 44.0 | 3.28e-01 | 100.0% | 50.2% |
| 3575038 | 109.4.1.264 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › RMD1-3 | 0.52 | 46.0 | 3.34e-01 | 100.0% | 66.1% |
| 3940779 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.51 | 39.0 | 3.88e-01 | 82.5% | 88.6% |
| 3220643 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.51 | 45.0 | 4.00e-01 | 99.0% | 98.6% |
| 4945181 | 3651.1.1.1 ↗ | alpha bundles › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › IF-2B | 0.51 | 44.0 | 4.07e-01 | 100.0% | 97.7% |
D2
medium
residues 47-64_88-119
Domain cluster:
representative
D3
medium
residues 120-145_282-328
Domain cluster:
representative
CATH (1)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1t3aA00 | 3.90.1240.10 | Alpha Beta › Alpha-Beta Complex › Zincin-like › "Metalloproteases (""zincins""), catalytic domain like" | 0.53 | 40.0 | 2.61e-01 | 83.6% | 50.2% |
D4
medium
residues 146-245
Domain cluster:
rep: RdRp__YP_009337885__Hubei_tetragnatha_maxillosa_virus_8__1923250__D61-84_149-215_309-325
CATH (1)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1dw9A02 | 3.30.1160.10 | Alpha Beta › 2-Layer Sandwich › Cyanate Lyase; Chain: A, domain 2 › Cyanate lyase, C-terminal domain | 0.62 | 22.0 | 2.60e-01 | 74.0% | 41.2% |
ECOD (6)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3954143 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.68 | 58.0 | 4.82e-01 | 98.0% | 53.1% |
| 3810414 | 812.2.1.1 ↗ | a+b duplicates or obligate multimers › MinE-like › Cyanase C-terminal domain › Cyanase C-terminal domain › Cyanate_lyase | 0.66 | 24.0 | 2.65e-01 | 73.0% | 38.7% |
| 4799073 | 309.1.1.4 ↗ | a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › Peptidase_M16_C | 0.60 | 26.0 | 2.66e-01 | 73.0% | 37.8% |
| 3731446 | 323.1.1.0 ↗ | a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases | 0.52 | 34.0 | 2.83e-01 | 70.0% | 34.6% |
| 3312666 | 221.1.1.0 ↗ | a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like | 0.52 | 25.0 | 2.91e-01 | 71.0% | 61.4% |
| 4938456 | 244.2.1.0 ↗ | a+b two layers › FAD-linked reductases, C-terminal domain-like › FAD/NAD-linked reduatases, dimerisation (C-terminal) domain › FAD/NAD-linked reduatases, dimerisation (C-terminal) domain | 0.52 | 30.0 | 3.21e-01 | 100.0% | 66.3% |
D5
medium
residues 246-281_371-447
Domain cluster:
rep: RdRp__YP_009329875__Hubei_partiti-like_virus_11__1923017__D203-236_315-377