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RdRp

Euk-Vir

Pistachio_ampelovirus_A

RdRp__YP_010086800__Pistachio_ampelovirus_A__2093224

Identity

Accession:
YP_010086800 ↗
Protein ID:
RdRp
Kingdom:
euk

Quality

88.3 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 51-67_394-473
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00978.27 best RdRP_2 46.2 4.30e-12 90.7% 17.7%
D2 medium residues 68-120
PDB
Domain cluster: representative
ECOD (2)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3469374 207.1.1.0 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats 0.55 43.0 2.67e-01 100.0% 62.3%
5038798 7524.1.1.1 a/b three-layered sandwiches › ALDH-like › ALDH-like › ALDH-like › Aldedh 0.51 35.0 2.29e-01 77.4% 17.7%
D3 medium residues 121-159_191-216
PDB
Domain cluster: representative
CATH (6)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3e2dA03 1.10.1200.140 Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › Alkaline phosphatase, crown domain 0.59 31.0 3.23e-01 72.3% 52.5%
3mopK00 1.10.533.10 Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas 0.57 42.0 3.76e-01 78.5% 92.5%
4nqwA02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.55 39.0 3.92e-01 73.8% 93.8%
3mliA01 1.10.3350.10 Mainly Alpha › Orthogonal Bundle › HP0242-like fold › HP0242-like domain 0.52 41.0 3.93e-01 93.8% 93.9%
1qr0A01 3.90.470.20 Alpha Beta › Alpha-Beta Complex › Ribosomal Protein L22; Chain A › 4'-phosphopantetheinyl transferase domain 0.52 40.0 3.28e-01 84.6% 89.6%
4errB00 1.20.58.1190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.51 41.0 3.86e-01 90.8% 92.8%
ECOD (4)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4303963 101.1.1.42 alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4_2 0.58 44.0 4.20e-01 81.5% 88.0%
4030134 101.1.10.3 alpha arrays › HTH › HTH › Cyclin-like › TFIIB 0.55 35.0 2.83e-01 89.2% 31.1%
3693753 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.54 41.0 3.92e-01 86.2% 98.8%
3386706 221.8.1.0 a+b two layers › beta-Grasp › GfcC › GfcC 0.50 38.0 3.04e-01 81.5% 48.5%
D4 medium residues 160-190_251-311
PDB
Domain cluster: representative
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF00978.27 best RdRP_2 53.7 2.30e-14 67.4% 13.6%
PF00978.27 RdRP_2 29.7 4.40e-07 35.9% 7.3%
CATH (3)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3g3oA00 3.20.100.30 Alpha Beta › Alpha-Beta Barrel › mRNA Triphosphatase Cet1; Chain A › VTC, catalytic tunnel domain 0.57 45.0 3.19e-01 84.8% 71.5%
3llcA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.54 44.0 3.28e-01 93.5% 68.2%
7v5yA01 3.40.1620.10 Alpha Beta › 3-Layer(aba) Sandwich › YefM-like fold › YefM-like domain 0.52 26.0 3.19e-01 91.3% 78.4%
ECOD (8)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3681837 304.48.1.1 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.68 61.0 4.78e-01 100.0% 75.9%
3983816 304.48.1.1 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.68 62.0 4.45e-01 100.0% 54.0%
3934288 304.48.1.1 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.67 60.0 4.71e-01 100.0% 86.8%
3241316 304.48.1.1 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.66 58.0 3.99e-01 100.0% 42.4%
3724547 4317.1.1.1 a+b duplicates or obligate multimers › YdfO-like › YdfO-like › YdfO-like › DUF1398 0.63 27.0 3.22e-01 75.0% 56.7%
4456383 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.59 52.0 3.68e-01 100.0% 52.8%
3177022 3873.1.1.1 a+b two layers › Serine/threonine-protein kinase GCN2 C-terminal domain › Serine/threonine-protein kinase GCN2 C-terminal domain › Serine/threonine-protein kinase GCN2 C-terminal domain › HGTP_anticodon2 0.56 47.0 4.28e-01 91.3% 87.9%
4015596 3873.1.1.0 a+b two layers › Serine/threonine-protein kinase GCN2 C-terminal domain › Serine/threonine-protein kinase GCN2 C-terminal domain › Serine/threonine-protein kinase GCN2 C-terminal domain 0.51 41.0 3.84e-01 90.2% 90.8%
D5 medium residues 217-250_376-393
PDB
Domain cluster: representative
CATH (7)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1h65B00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.58 43.0 2.84e-01 86.5% 41.4%
3w3wA02 6.10.140.1700 Special › Helix non-globular › Helix Hairpins › 0.54 31.0 3.66e-01 82.7% 93.5%
4g08A01 3.55.50.30 Alpha Beta › 3-Layer(bab) Sandwich › Phage tail protein beta-alpha-beta fold › 0.53 43.0 4.04e-01 100.0% 100.0%
1e7uA04 3.30.1010.10 Alpha Beta › 2-Layer Sandwich › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 4 › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 4 0.53 39.0 2.97e-01 88.5% 90.5%
1ou5A01 3.30.460.10 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2 0.53 36.0 2.72e-01 73.1% 52.9%
1htwA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.52 39.0 2.95e-01 90.4% 35.4%
6vu9A02 3.30.930.10 Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 0.50 40.0 2.66e-01 100.0% 83.2%
ECOD (5)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3758879 391.1.2.1 few secondary structure elements › Fibronectin type I module-like › Fibronectin type I module-like › VWC domain-related › VWC 0.58 36.0 3.97e-01 71.2% 91.4%
4588391 2007.1.16.0 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Iron-sulphur enzyme Dph2 0.57 41.0 3.04e-01 76.9% 31.4%
9594 2004.1.1.118 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AIG1 0.57 42.0 2.82e-01 86.5% 41.2%
3282754 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.55 38.0 2.78e-01 76.9% 37.7%
4208861 2004.1.1.224 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › P-loop_SecA 0.50 41.0 2.74e-01 96.2% 70.6%
D6 medium residues 312-375
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00978.27 best RdRP_2 64.7 1.10e-17 100.0% 14.5%
CATH (23)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1ra6A02 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.78 68.0 5.78e-01 98.4% 71.7%
3h5xA03 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.77 69.0 5.65e-01 100.0% 66.4%
1pu1A00 3.30.300.100 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › MTH677-like 0.67 54.0 4.78e-01 87.5% 73.6%
1gx5A03 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.66 57.0 4.70e-01 100.0% 58.2%
3cjsA00 3.30.70.1170 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Sun protein; domain 3 0.64 44.0 4.53e-01 92.2% 79.3%
1h3dA03 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.60 46.0 4.57e-01 90.6% 82.1%
3ewgA00 3.30.70.940 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › NusG, N-terminal domain 0.60 48.0 4.59e-01 93.8% 78.8%
2d9oA00 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.58 49.0 4.29e-01 96.9% 67.0%
4nogA01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.58 48.0 3.65e-01 96.9% 36.8%
3ruyA01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.58 48.0 3.78e-01 100.0% 42.7%
2j0wA04 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.58 48.0 4.61e-01 96.9% 86.7%
2pb2B01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.58 47.0 3.81e-01 98.4% 47.2%
3oksA01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.57 47.0 3.55e-01 96.9% 40.9%
3n5mB01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.57 49.0 3.62e-01 98.4% 45.5%
1xxaC00 3.30.1360.40 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.57 40.0 3.90e-01 76.6% 71.2%
3dxvA01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.57 49.0 3.79e-01 100.0% 46.7%
1iq0A02 3.30.1360.70 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › Arginyl tRNA synthetase N-terminal domain 0.55 45.0 4.03e-01 98.4% 77.0%
1vefA01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.54 45.0 3.60e-01 100.0% 43.4%
2cy8A01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.53 40.0 3.08e-01 92.2% 41.9%
2ykyB01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.52 43.0 3.23e-01 100.0% 40.2%
2hg7A00 3.30.56.60 Alpha Beta › 2-Layer Sandwich › Phenylalanyl-tRNA Synthetase; Chain B, domain 1 › XkdW-like 0.52 36.0 3.66e-01 75.0% 91.7%
1bjtA05 3.90.199.10 Alpha Beta › Alpha-Beta Complex › Topoisomerase II; domain 5 › Topoisomerase II, domain 5 0.52 44.0 3.03e-01 100.0% 88.4%
1fxkB00 1.10.287.370 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.51 34.0 2.82e-01 92.2% 40.4%
ECOD (27)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5043562 3501.1.1.0 a+b two layers › protein PCC1 › protein PCC1 › protein PCC1 0.65 46.0 4.61e-01 75.0% 87.7%
4636695 304.36.1.1 a+b two layers › Alpha-beta plaits › YajQ-like › YajQ-like › DUF520 0.65 53.0 5.25e-01 92.2% 89.7%
4984434 304.3.1.0 a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain 0.64 50.0 5.07e-01 90.6% 86.2%
3601206 304.120.1.0 a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in ThiI › Ferredoxin-like domain in ThiI 0.62 51.0 4.94e-01 96.9% 81.3%
3744865 304.3.1.0 a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain 0.61 46.0 4.75e-01 84.4% 90.0%
4970115 304.3.1.0 a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain 0.60 48.0 4.76e-01 92.2% 84.3%
4955790 3016.1.1.2 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › Aminotran_3 0.59 50.0 4.30e-01 96.9% 62.9%
1566648 3016.1.1.2 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › Aminotran_3 0.58 48.0 4.29e-01 98.4% 63.0%
3963077 3016.1.1.0 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases 0.58 48.0 4.42e-01 98.4% 70.0%
5041665 304.3.1.0 a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain 0.58 45.0 4.40e-01 92.2% 80.0%
3359944 304.3.1.1 a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain › HMA 0.58 43.0 4.49e-01 89.1% 96.4%
3786964 101.1.10.1 alpha arrays › HTH › HTH › Cyclin-like › Cyclin_N 0.58 46.0 3.57e-01 100.0% 51.9%
3301018 304.3.1.0 a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain 0.58 43.0 4.54e-01 89.1% 100.0%
4008923 304.3.1.0 a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain 0.58 43.0 4.24e-01 93.8% 77.1%
4976232 3016.1.1.2 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › Aminotran_3 0.57 48.0 4.34e-01 100.0% 68.9%
4610155 3016.1.1.2 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › Aminotran_3 0.57 47.0 4.26e-01 100.0% 66.3%
5077572 304.128.1.0 a+b two layers › Alpha-beta plaits › ferredoxin-like domain in periplasmic region of MacB › ferredoxin-like domain in periplasmic region of MacB 0.57 45.0 4.36e-01 92.2% 77.3%
4129052 3016.1.1.2 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › Aminotran_3 0.56 46.0 4.16e-01 98.4% 65.3%
3430077 3016.1.1.2 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › Aminotran_3 0.56 47.0 4.63e-01 98.4% 92.6%
4157871 880.1.1.1 a+b duplicates or obligate multimers › ADC synthase › ADC synthase › ADC synthase › Chorismate_bind 0.56 45.0 2.71e-01 92.2% 20.4%
2161921 3016.1.1.0 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases 0.56 46.0 4.30e-01 100.0% 74.1%
3964246 7577.1.1.2 a/b three-layered sandwiches › PLP-dependent transferases › PLP-dependent transferases › PLP-dependent transferases › Aminotran_3 0.56 46.0 2.86e-01 98.4% 14.7%
4194365 7577.1.1.0 a/b three-layered sandwiches › PLP-dependent transferases › PLP-dependent transferases › PLP-dependent transferases 0.55 45.0 2.62e-01 98.4% 8.5%
3169399 4099.1.1.11 a+b two layers › Kinetochore globular domain-like › Kinetochore globular domain-like › Kinetochore globular domain-like › Med14 0.55 47.0 3.94e-01 98.4% 83.5%
4327650 7577.1.1.2 a/b three-layered sandwiches › PLP-dependent transferases › PLP-dependent transferases › PLP-dependent transferases › Aminotran_3 0.54 45.0 2.81e-01 98.4% 14.9%
4410774 101.1.8.0 alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes 0.53 40.0 3.38e-01 82.8% 51.3%
5058284 2004.1.1.14 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › GTP_EFTU 0.50 41.0 3.01e-01 98.4% 82.9%