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Replicase

Euk-Vir

Donkey_orchid_symptomless_virus

Replicase__YP_008828152__Donkey_orchid_symptomless_virus__1400526

Identity

Accession:
YP_008828152 ↗
Protein ID:
Replicase
Kingdom:
euk

Quality

72.1 mean pLDDT

Taxonomy

Orthornavirae› Kitrinoviricota› Alsuviricetes› Tymovirales› Alphaflexiviridae› Platypuvirus› Donkey_orchid_symptomless_virus

TaxID: 1400526

Cluster

View cluster (13 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 270-396
PDB
Domain cluster: representative
CATH (6)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2cqnA00 1.10.10.440 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › FF domain 0.66 38.0 4.66e-01 81.9% 90.9%
3s64A00 1.10.225.10 Mainly Alpha › Orthogonal Bundle › NK-Lysin › Saposin-like 0.64 40.0 4.83e-01 99.2% 98.8%
3lmfA00 1.20.1270.360 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.59 33.0 3.57e-01 81.1% 62.4%
2yfaA02 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.56 35.0 3.63e-01 79.5% 66.4%
3vokA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.53 37.0 3.37e-01 71.7% 78.4%
3frqB00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.52 37.0 3.31e-01 72.4% 94.0%
ECOD (9)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3441901 632.1.1.13 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain › Rx_N 0.64 33.0 4.12e-01 83.5% 80.0%
3270837 174.1.1.33 ↗ few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Erg28 0.59 37.0 3.83e-01 78.0% 64.5%
4978846 633.21.1.0 ↗ alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 0.57 32.0 3.43e-01 81.1% 61.4%
2808456 3651.1.1.1 ↗ alpha bundles › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › IF-2B 0.56 37.0 3.96e-01 87.4% 77.8%
3907338 101.1.1.97 ↗ alpha arrays › HTH › HTH › Three-helical HTH › DUF4806 0.56 35.0 3.78e-01 77.2% 72.7%
4996728 174.1.1.0 ↗ few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.54 34.0 3.55e-01 81.1% 67.8%
3574498 3291.1.1.146 ↗ alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › V_ATPase_I 0.53 47.0 3.81e-01 100.0% 79.6%
4005041 601.4.1.6 ↗ alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › TorS_sensor_domain 0.53 35.0 3.54e-01 79.5% 67.2%
3673448 192.4.1.37 ↗ alpha bundles › Long alpha-hairpin › Ribosomal protein L29 (L29p) › Ribosomal protein L29 (L29p) › Cas1_AcylT 0.51 37.0 3.80e-01 98.4% 80.0%
D2 high residues 778-879
PDB
Domain cluster: rep: TGB1_protein__NP_619560__Garlic_latent_virus__12458__D129-228
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF01443.25 best Viral_helicase1 35.3 1.60e-08 76.5% 29.4%
CATH (56)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3upuA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.86 63.0 5.78e-01 76.5% 98.5%
3e1sA03 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.78 69.0 6.10e-01 94.1% 93.6%
1w36D03 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.78 69.0 5.65e-01 94.1% 98.8%
6vsxA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.76 70.0 5.99e-01 100.0% 93.7%
3vkwA03 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.75 70.0 6.10e-01 100.0% 71.6%
3dmnA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.75 69.0 5.87e-01 100.0% 85.7%
5rl9B01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.73 68.0 5.92e-01 100.0% 81.9%
1hv8A02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.71 64.0 5.59e-01 99.0% 98.7%
4ceiB01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.71 63.0 5.23e-01 98.0% 97.2%
1z6aA01 3.40.50.10810 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Tandem AAA-ATPase domain 0.71 63.0 5.03e-01 100.0% 88.3%
2hyiC02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.70 63.0 5.37e-01 100.0% 91.0%
4ljyA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.70 64.0 5.17e-01 100.0% 83.8%
3rc3A03 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.70 63.0 5.45e-01 100.0% 90.6%
1wp9A01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.69 60.0 4.89e-01 98.0% 80.9%
2p6nA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.69 63.0 5.38e-01 100.0% 93.8%
1pjrA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.68 61.0 4.89e-01 99.0% 84.7%
4w7sA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.67 60.0 4.95e-01 100.0% 80.6%
1rifA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.67 59.0 4.86e-01 99.0% 78.6%
2zpaA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.67 59.0 5.41e-01 99.0% 87.5%
3mwyW03 3.40.50.10810 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Tandem AAA-ATPase domain 0.66 58.0 4.30e-01 98.0% 61.6%
7a8rA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.65 58.0 4.71e-01 100.0% 82.4%
3b85A00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.64 57.0 4.70e-01 99.0% 78.6%
1w4rA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.64 57.0 5.27e-01 100.0% 93.9%
8kcaB01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.64 56.0 4.77e-01 99.0% 89.5%
4xjxA03 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.63 55.0 4.60e-01 100.0% 84.3%
3eccA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.63 57.0 4.89e-01 100.0% 81.5%
2c61A00 3.40.50.12240 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.63 55.0 3.69e-01 100.0% 46.6%
6yhrA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.62 54.0 4.35e-01 98.0% 97.6%
2qgzA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.61 55.0 4.56e-01 100.0% 67.2%
3ua3B01 3.20.20.150 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Divalent-metal-dependent TIM barrel enzymes 0.60 52.0 3.84e-01 97.1% 98.2%
2acfB00 3.40.220.10 Alpha Beta › 3-Layer(aba) Sandwich › Leucine Aminopeptidase, subunit E; domain 1 › Leucine Aminopeptidase, subunit E, domain 1 0.59 50.0 4.33e-01 97.1% 90.2%
1jqlB00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.59 52.0 4.75e-01 100.0% 82.9%
6h0cA02 3.40.50.360 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Flavodoxin domain 0.59 47.0 4.18e-01 89.2% 73.7%
1vpyA00 3.20.20.410 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Protein of unknown function UPF0759 0.58 51.0 3.92e-01 100.0% 99.2%
3ejgA00 3.40.220.10 Alpha Beta › 3-Layer(aba) Sandwich › Leucine Aminopeptidase, subunit E; domain 1 › Leucine Aminopeptidase, subunit E, domain 1 0.58 51.0 4.43e-01 100.0% 94.5%
4ldaB00 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.58 46.0 4.35e-01 88.2% 77.2%
3co5A00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.58 51.0 4.70e-01 100.0% 81.3%
4i4cB00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.57 46.0 3.12e-01 88.2% 48.2%
3e0xA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.57 46.0 3.52e-01 88.2% 81.2%
3gdgA00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.56 49.0 3.73e-01 100.0% 71.5%
3tejA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.56 45.0 3.24e-01 88.2% 60.0%
1vpqA00 3.20.20.410 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Protein of unknown function UPF0759 0.56 48.0 3.65e-01 98.0% 98.8%
4rgyA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.54 43.0 3.35e-01 87.3% 59.5%
4az3A00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.54 40.0 3.06e-01 78.4% 52.5%
3qyfA01 3.40.50.10770 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Hypothetical protein VC1899 like domain (Restriction endonuclease-like) 0.54 47.0 4.08e-01 98.0% 93.9%
3v4cA02 3.40.309.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 2 › Aldehyde Dehydrogenase; Chain A, domain 2 0.54 46.0 3.86e-01 99.0% 91.1%
2qq5A00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.54 46.0 3.60e-01 98.0% 71.4%
1ez0A02 3.40.309.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 2 › Aldehyde Dehydrogenase; Chain A, domain 2 0.53 45.0 3.84e-01 99.0% 95.7%
2m9mA00 3.40.50.10130 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.53 42.0 3.87e-01 88.2% 70.5%
2k2qB00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.52 42.0 3.24e-01 88.2% 61.6%
4p1zA00 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.52 37.0 3.55e-01 76.5% 84.3%
1xmxA01 3.40.50.10770 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Hypothetical protein VC1899 like domain (Restriction endonuclease-like) 0.52 46.0 4.13e-01 99.0% 89.4%
4fb7A00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.51 44.0 3.33e-01 99.0% 82.3%
2gzsA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.51 40.0 3.11e-01 88.2% 71.9%
2p4gA00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.51 44.0 3.42e-01 100.0% 94.0%
5f7vA00 3.40.190.10 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II 0.50 43.0 3.00e-01 99.0% 54.6%
ECOD (77)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3589167 2004.1.1.62 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Viral_helicase1 0.81 63.0 5.62e-01 81.4% 78.6%
3603695 2004.1.1.496 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Viral_helicase1, UvrD_C_2 0.81 71.0 5.73e-01 93.1% 97.8%
3760903 2004.1.1.203 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › UvrD_C_2 0.81 62.0 5.08e-01 80.4% 98.3%
3278699 2004.1.1.203 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › UvrD_C_2 0.81 71.0 6.11e-01 94.1% 80.6%
5015395 2004.1.1.186 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_12 0.80 74.0 5.93e-01 100.0% 94.7%
None — 0.78 69.0 6.08e-01 94.1% 100.0%
3590487 2004.1.1.203 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › UvrD_C_2 0.78 69.0 6.07e-01 94.1% 99.3%
3385675 2004.1.1.298 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Herpes_Helicase 0.78 69.0 6.07e-01 94.1% 84.8%
3439817 2004.1.1.186 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_12 0.78 72.0 5.60e-01 100.0% 84.8%
3970065 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.78 69.0 5.76e-01 94.1% 97.0%
3372759 2004.1.1.135 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › PIF1 0.78 69.0 4.93e-01 94.1% 54.1%
3682367 2004.1.1.496 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Viral_helicase1, UvrD_C_2 0.78 63.0 5.68e-01 85.3% 98.5%
3807611 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.78 69.0 5.87e-01 94.1% 92.9%
3777175 2004.1.1.203 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › UvrD_C_2 0.77 67.0 5.55e-01 93.1% 97.6%
3874017 2004.1.1.496 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Viral_helicase1, UvrD_C_2 0.76 66.0 5.42e-01 93.1% 97.8%
3290749 2004.1.1.203 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › UvrD_C_2 0.76 67.0 5.72e-01 93.1% 82.6%
3561762 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.76 59.0 4.74e-01 81.4% 92.1%
3648251 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.76 67.0 5.12e-01 94.1% 95.5%
2142440 2004.1.1.186 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_12 0.76 69.0 5.47e-01 100.0% 88.3%
3683589 2004.1.1.135 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › PIF1 0.75 66.0 4.37e-01 94.1% 40.5%
1230975 2004.1.1.203 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › UvrD_C_2 0.75 69.0 5.87e-01 100.0% 85.7%
None — 0.74 69.0 4.96e-01 100.0% 54.4%
3890170 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.73 65.0 5.75e-01 94.1% 81.4%
3729346 2004.1.1.30 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C 0.73 67.0 4.78e-01 100.0% 63.2%
3594466 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.73 66.0 5.68e-01 100.0% 94.4%
2095415 2004.1.1.186 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_12 0.73 67.0 5.72e-01 100.0% 75.6%
3653971 2004.1.1.30 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C 0.71 65.0 5.21e-01 100.0% 77.4%
3891480 2004.1.1.135 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › PIF1 0.71 63.0 4.22e-01 94.1% 31.8%
3711265 2004.1.1.30 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C 0.71 64.0 5.60e-01 100.0% 97.4%
3592135 2004.1.1.30 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C 0.71 64.0 4.88e-01 100.0% 64.3%
3797023 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.70 64.0 4.77e-01 100.0% 61.6%
3980676 2004.1.1.203 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › UvrD_C_2 0.70 64.0 4.90e-01 100.0% 89.1%
3174411 2004.1.1.455 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › UvrD-helicase, UvrD_C, UvrD_C_2 0.70 64.0 3.84e-01 100.0% 53.0%
3818302 2004.1.1.30 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C 0.70 62.0 4.37e-01 98.0% 90.5%
4937972 2004.1.1.30 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C 0.69 63.0 4.60e-01 100.0% 75.9%
3424253 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.69 63.0 5.27e-01 100.0% 90.6%
3835014 2004.1.1.30 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C 0.69 60.0 4.82e-01 97.1% 97.0%
5026524 2004.1.1.30 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C 0.68 59.0 5.03e-01 94.1% 90.9%
4002561 2004.1.1.30 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C 0.68 62.0 4.73e-01 100.0% 71.7%
4994367 2004.1.1.123 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_RecD 0.67 60.0 4.86e-01 100.0% 77.5%
3735883 2004.1.1.25 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SNF2-rel_dom,Helicase_C,SnAC 0.67 60.0 3.67e-01 100.0% 35.3%
3945467 2004.1.1.256 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ssDNA_TraI_N 0.66 57.0 5.49e-01 94.1% 97.4%
3473985 2004.1.1.23 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SNF2-rel_dom 0.66 58.0 4.40e-01 99.0% 63.6%
3282703 2004.1.1.30 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C 0.66 59.0 4.62e-01 100.0% 88.2%
5036017 2006.1.3.2 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.65 50.0 3.84e-01 82.4% 79.1%
5001121 2004.1.1.144 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD_2 0.64 56.0 4.26e-01 99.0% 86.4%
3678132 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.63 57.0 4.31e-01 98.0% 79.6%
5066167 2007.1.3.4 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › B12-binding 0.62 50.0 4.36e-01 89.2% 85.6%
3741638 2007.2.5.1 ↗ a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › Rhodanese/Cell cycle control phosphatase › Rhodanese 0.62 47.0 4.72e-01 82.4% 92.4%
4976539 2007.1.3.4 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › B12-binding 0.61 49.0 3.99e-01 89.2% 79.5%
5077011 2007.1.3.4 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › B12-binding 0.61 49.0 4.11e-01 89.2% 81.1%
5027609 2004.1.1.196 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_22 0.60 53.0 4.44e-01 100.0% 73.5%
4009283 2004.1.1.196 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_22 0.60 52.0 4.51e-01 99.0% 79.4%
2719122 7529.1.1.1 ↗ a/b three-layered sandwiches › Macro domain-like › Macro domain-like › Macro domain-like › Macro 0.59 50.0 4.33e-01 97.1% 91.4%
3496966 2006.1.1.0 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like 0.59 52.0 4.08e-01 100.0% 53.0%
3954103 7579.1.1.10 ↗ a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Thioesterase 0.59 47.0 3.62e-01 88.2% 78.7%
4991289 2003.1.5.66 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 0.59 45.0 3.85e-01 83.3% 64.0%
4418350 2006.1.3.2 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.59 49.0 3.92e-01 89.2% 98.5%
5056466 2007.1.3.4 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › B12-binding 0.57 50.0 4.12e-01 98.0% 77.9%
3442635 2004.1.1.56 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › NB-ARC 0.57 50.0 4.24e-01 100.0% 76.1%
4255201 2484.1.1.7 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Ribosomal_S11 0.57 39.0 3.88e-01 70.6% 89.1%
3436764 2004.1.1.56 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › NB-ARC 0.57 50.0 4.08e-01 100.0% 66.0%
4988240 2007.1.3.4 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › B12-binding 0.57 49.0 4.06e-01 98.0% 81.1%
3432125 2003.1.1.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains 0.57 47.0 3.83e-01 93.1% 57.1%
3653832 207.1.1.103 ↗ beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › LRR_R13L1-DRL21 0.57 46.0 2.78e-01 88.2% 18.0%
4974821 2007.1.3.4 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › B12-binding 0.56 48.0 3.98e-01 98.0% 77.9%
4999742 2004.1.1.1 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA 0.56 48.0 4.43e-01 100.0% 83.6%
4837846 7529.1.1.0 ↗ a/b three-layered sandwiches › Macro domain-like › Macro domain-like › Macro domain-like 0.56 49.0 4.19e-01 100.0% 90.2%
3613184 2007.1.3.0 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like 0.55 40.0 3.37e-01 76.5% 64.4%
4972258 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.54 47.0 4.06e-01 100.0% 78.8%
3837720 2004.1.1.56 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › NB-ARC 0.53 46.0 4.01e-01 100.0% 71.2%
3785857 7514.1.1.3 ↗ a/b three-layered sandwiches › Ferredoxin reductase-like, C-terminal NADP-linked domain › Ferredoxin reductase-like, C-terminal NADP-linked domain › Ferredoxin reductase-like, C-terminal NADP-linked domain › NAD_binding_6 0.53 43.0 3.63e-01 88.2% 56.9%
5054286 2007.3.1.6 ↗ a/b three-layered sandwiches › Flavodoxin-like › Succinyl-CoA synthetase domains › Succinyl-CoA synthetase domains › Ligase_CoA_2 0.53 46.0 4.12e-01 100.0% 88.9%
3456749 207.1.1.95 ↗ beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › LRR_14 0.53 44.0 3.28e-01 92.2% 47.4%
4140818 7528.1.1.1 ↗ a/b three-layered sandwiches › Phosphoglucomutase, first 3 domains › Phosphoglucomutase, first 3 domains › Phosphoglucomutase, first 3 domains › PGM_PMM_I 0.52 37.0 3.20e-01 76.5% 77.1%
4513736 2002.1.1.174 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › MR_MLE_C 0.51 45.0 3.47e-01 100.0% 65.2%
3599511 2006.1.6.12 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA_2 0.50 40.0 3.11e-01 89.2% 63.5%
D3 medium residues 11-67
PDB
D4 medium residues 68-259
PDB
Domain cluster: rep: uncovered_polypeptide_polyprotein__YP_001086452_0-758__Chrysanthemum_virus_B__12165__D72-292
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF01660.23 best Vmethyltransf 160.8 6.10e-47 100.0% 68.5%
D5 medium residues 563-620
PDB
D6 medium residues 1106-1137_1258-1337
PDB
Domain cluster: representative
CATH (18)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2ra1A03 1.20.58.770 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.67 38.0 4.83e-01 75.9% 100.0%
2jbwA01 1.20.1440.110 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › acylaminoacyl peptidase 0.64 47.0 4.84e-01 90.2% 82.5%
2mtqA00 1.20.58.130 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.60 39.0 4.53e-01 75.0% 98.6%
2v6yA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.59 38.0 4.50e-01 73.2% 97.3%
4u7iA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.58 43.0 4.63e-01 78.6% 94.6%
2hqtK00 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.58 42.0 4.18e-01 97.3% 73.5%
2d9dA00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.57 40.0 4.34e-01 77.7% 89.9%
1t72A02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.57 41.0 4.41e-01 75.9% 94.9%
1j1jA01 1.20.58.190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 0.57 44.0 4.16e-01 81.2% 80.3%
3b0pA02 1.20.120.1460 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.56 31.0 3.68e-01 72.3% 80.0%
1yg2A02 6.10.140.190 Special › Helix non-globular › Helix Hairpins › 0.56 39.0 4.24e-01 71.4% 97.8%
5hayA02 1.25.40.440 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Nucleoporin, helical domain, central subdomain 0.54 36.0 4.10e-01 93.8% 94.9%
1iwpG02 1.10.1510.20 Mainly Alpha › Orthogonal Bundle › Hypothetical Protein Yqey; Chain: A; domain1 › Propanediol/glycerol dehydratase, small subunit 0.54 31.0 3.35e-01 78.6% 65.6%
5jrcA00 1.20.58.2140 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.54 47.0 3.99e-01 96.4% 74.7%
2w02B01 1.10.150.640 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › AcsD, thumb domain, helical bundle 0.53 27.0 3.21e-01 79.5% 70.3%
3bt5A00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.51 37.0 3.42e-01 76.8% 96.7%
2b1eA02 1.20.1310.30 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › 0.50 43.0 3.96e-01 96.4% 90.7%
5c9eB01 1.20.1280.80 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.50 34.0 3.77e-01 89.3% 89.7%
ECOD (15)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3456188 109.7.1.10 ↗ alpha superhelices › Repetitive alpha hairpins › Cytochrome c oxidase subunit E › Cytochrome c oxidase subunit E › WAV3_C 0.69 39.0 4.68e-01 76.8% 84.0%
4022256 109.7.1.14 ↗ alpha superhelices › Repetitive alpha hairpins › Cytochrome c oxidase subunit E › Cytochrome c oxidase subunit E › PF28749 0.65 42.0 4.78e-01 87.5% 90.0%
4627927 140.1.1.7 ↗ alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › DALR_2 0.65 44.0 4.02e-01 81.2% 53.1%
3750030 604.12.1.15 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › Mito_morph_reg 0.62 45.0 4.87e-01 79.5% 94.4%
3915114 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.61 43.0 4.15e-01 73.2% 89.2%
3257419 174.1.1.0 ↗ few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.61 38.0 3.76e-01 73.2% 57.5%
3500905 604.13.1.1 ↗ alpha bundles › Spectrin repeat-like › USP8 N-terminal domain-like › USP8 N-terminal domain-like › USP8_dimer 0.60 43.0 4.15e-01 88.4% 66.4%
5072045 604.10.1.0 ↗ alpha bundles › Spectrin repeat-like › Enzyme IIa from lactose specific PTS, IIa-lac › Enzyme IIa from lactose specific PTS, IIa-lac 0.59 48.0 4.94e-01 87.5% 95.2%
3808969 109.4.1.359 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Exo70_C 0.59 50.0 3.24e-01 94.6% 48.5%
3610162 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.58 51.0 3.70e-01 100.0% 97.7%
3496842 109.4.1.504 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Ndc1_Nup 0.58 50.0 4.19e-01 97.3% 80.5%
3311612 109.4.1.1138 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SCAI 0.56 50.0 4.16e-01 100.0% 82.0%
3491110 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.56 41.0 4.16e-01 76.8% 90.0%
3528346 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.56 41.0 3.63e-01 77.7% 64.2%
3872783 604.3.1.1 ↗ alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › BAG 0.53 38.0 4.02e-01 75.0% 83.0%