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RifSed_csp1_19ft_3_scaffold_4_curated_prodigal-single.1__X__X__00298
Bact-VirRifSed_csp1_19ft_3_scaffold_4_curated_prodigal-single.1__X__X__00298
Identity
- Kingdom:
- phage
Quality
83.3
mean pLDDT
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 82-94_152-373
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01289.25 best | Thiol_cytolysin | 96.2 | 2.50e-27 | 93.2% | 58.6% |
CATH (5)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1s3rA03 | 3.40.30.40 | Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Perfringolysin | 0.72 | 40.0 | 5.39e-01 | 74.5% | 100.0% |
| 3cqfA03 | 3.40.30.40 | Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Perfringolysin | 0.68 | 36.0 | 4.93e-01 | 73.6% | 100.0% |
| 3uezC02 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.62 | 20.0 | 3.48e-01 | 75.3% | 83.1% |
| 1fx3B00 | 3.10.420.10 | Alpha Beta › Roll › Bacterial Protein-export protein SecB › SecB-like | 0.54 | 27.0 | 3.43e-01 | 82.1% | 75.8% |
| 4akrA02 | 3.90.1150.210 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › F-actin capping protein, beta subunit | 0.52 | 21.0 | 2.65e-01 | 77.4% | 57.1% |
ECOD (26)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1290657 | 5089.1.1.1 ↗ | beta complex topology › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › Thiol_cytolysin | 0.80 | 76.0 | 6.38e-01 | 100.0% | 80.1% |
| 2554394 | 5089.1.1.1 ↗ | beta complex topology › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › Thiol_cytolysin | 0.79 | 75.0 | 6.36e-01 | 100.0% | 83.5% |
| 146661 | 5089.1.1.1 ↗ | beta complex topology › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › Thiol_cytolysin | 0.79 | 75.0 | 6.36e-01 | 99.6% | 82.8% |
| 4807171 | 5089.1.1.1 ↗ | beta complex topology › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › Thiol_cytolysin | 0.77 | 70.0 | 6.55e-01 | 93.2% | 99.3% |
| 1883539 | 5089.1.1.1 ↗ | beta complex topology › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › Thiol_cytolysin | 0.77 | 73.0 | 6.20e-01 | 99.6% | 82.9% |
| 4847420 | 5089.1.1.1 ↗ | beta complex topology › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › Thiol_cytolysin | 0.73 | 64.0 | 6.27e-01 | 92.3% | 99.6% |
| 3253452 | 5089.1.1.6 ↗ | beta complex topology › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › MACPF_SNTX | 0.71 | 64.0 | 6.14e-01 | 94.9% | 100.0% |
| 3731709 | 5089.1.1.6 ↗ | beta complex topology › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › MACPF_SNTX | 0.71 | 62.0 | 5.99e-01 | 91.5% | 96.2% |
| 3907836 | 5089.1.1.6 ↗ | beta complex topology › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › MACPF_SNTX | 0.70 | 63.0 | 6.05e-01 | 94.9% | 98.5% |
| 3851319 | 5089.1.1.2 ↗ | beta complex topology › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › MACPF | 0.69 | 60.0 | 5.22e-01 | 89.8% | 86.4% |
| 3252819 | 5089.1.1.0 ↗ | beta complex topology › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains | 0.69 | 61.0 | 5.91e-01 | 91.9% | 98.8% |
| 4149602 | 5089.1.1.0 ↗ | beta complex topology › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains | 0.67 | 58.0 | 5.93e-01 | 90.6% | 99.6% |
| 3896885 | 5089.1.1.0 ↗ | beta complex topology › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains | 0.67 | 60.0 | 5.87e-01 | 94.9% | 100.0% |
| 4018549 | 5089.1.1.6 ↗ | beta complex topology › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › MACPF_SNTX | 0.65 | 58.0 | 5.50e-01 | 95.3% | 98.2% |
| 3700014 | 5089.1.1.0 ↗ | beta complex topology › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains | 0.64 | 50.0 | 5.15e-01 | 86.4% | 84.4% |
| 4028879 | 5089.1.1.2 ↗ | beta complex topology › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › MACPF | 0.63 | 54.0 | 4.75e-01 | 91.5% | 85.1% |
| 3907094 | 5089.1.1.2 ↗ | beta complex topology › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › MACPF | 0.63 | 57.0 | 5.03e-01 | 95.7% | 95.2% |
| 4312104 | 5089.1.1.2 ↗ | beta complex topology › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › MACPF | 0.62 | 55.0 | 4.71e-01 | 96.2% | 95.8% |
| 3877717 | 5089.1.1.2 ↗ | beta complex topology › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › MACPF | 0.59 | 53.0 | 4.81e-01 | 95.7% | 93.5% |
| 3355949 | 5089.1.1.2 ↗ | beta complex topology › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › MACPF | 0.58 | 51.0 | 4.58e-01 | 94.9% | 91.4% |
| 3641744 | 5089.1.1.2 ↗ | beta complex topology › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › MACPF | 0.57 | 50.0 | 4.61e-01 | 94.9% | 91.2% |
| 3677084 | 5089.1.1.2 ↗ | beta complex topology › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › MACPF | 0.56 | 49.0 | 4.37e-01 | 94.9% | 91.3% |
| 3270448 | 5089.1.1.2 ↗ | beta complex topology › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › MACPF | 0.54 | 43.0 | 4.46e-01 | 85.1% | 88.4% |
| 3729752 | 5089.1.1.0 ↗ | beta complex topology › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains | 0.53 | 47.0 | 4.80e-01 | 94.5% | 97.4% |
| 3857913 | 5089.1.1.2 ↗ | beta complex topology › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › MACPF | 0.53 | 46.0 | 4.41e-01 | 91.1% | 87.4% |
| 3529429 | 5089.1.1.0 ↗ | beta complex topology › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains | 0.53 | 46.0 | 4.37e-01 | 91.5% | 87.3% |
D2
medium
residues 95-151
Domain cluster:
representative
CATH (1)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1pfoA01 | 3.90.840.10 | Alpha Beta › Alpha-Beta Complex › HIV-1 Reverse Transcriptase; Chain A, domain 3 › Thiol-activated cytolysin superfamily/Thiol-activated cytolysin, alpha-beta domain | 0.86 | 79.0 | 5.38e-01 | 100.0% | 31.7% |
ECOD (3)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 146661 | 5089.1.1.1 ↗ | beta complex topology › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › Thiol_cytolysin | 0.86 | 79.0 | 4.70e-01 | 100.0% | 16.1% |
| 3429058 | 304.9.1.1 ↗ | a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 | 0.54 | 38.0 | 3.30e-01 | 75.4% | 89.5% |
| 5056440 | 206.1.1.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase | 0.53 | 40.0 | 2.80e-01 | 91.2% | 83.7% |