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S16_GE16_scaffold_10741_prodigal-single.1XX__00005

Bact-Vir

S16_GE16_scaffold_10741_prodigal-single.1__X__X__00005

Identity

Kingdom:: phage

Quality

61.6 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

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Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 824-884

PDB

D2 medium residues 15-46_171-223

PDB

Domain cluster: rep: ON649702__UVF62572.1__X__00095__D231-262_382-434

CATH (18)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
2cfmA02	3.30.470.30	Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme	0.81	73.0	5.33e-01	95.3%	100.0%
3rtxA02	3.30.1490.430	Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 ›	0.80	56.0	5.40e-01	92.9%	63.9%
2hivA02	3.30.470.30	Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme	0.79	72.0	5.31e-01	97.6%	99.5%
1vs0A01	3.30.1490.70	Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 ›	0.78	64.0	6.69e-01	100.0%	97.4%
4d05A01	3.30.1490.70	Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 ›	0.78	64.0	6.79e-01	98.8%	98.7%
1fviA01	3.30.1490.70	Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 ›	0.78	68.0	7.06e-01	97.6%	100.0%
3l2pA02	3.30.1490.70	Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 ›	0.77	61.0	6.54e-01	91.8%	100.0%
1x9nA02	3.30.1490.70	Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 ›	0.75	64.0	6.47e-01	90.6%	91.7%
1a0iA01	3.30.1490.70	Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 ›	0.75	66.0	6.75e-01	97.6%	97.6%
6imjA01	3.30.470.30	Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme	0.75	62.0	4.69e-01	88.2%	100.0%
6rarI01	3.30.470.30	Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme	0.74	62.0	4.63e-01	89.4%	100.0%
5d1oA02	3.30.1490.70	Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 ›	0.72	58.0	6.22e-01	90.6%	100.0%
4pz6A02	3.30.470.30	Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme	0.70	64.0	4.59e-01	100.0%	91.1%
3qwuA02	3.30.470.30	Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme	0.66	57.0	4.45e-01	95.3%	100.0%
2r6fA03	3.30.1490.20	Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › ATP-grasp fold, A domain	0.57	44.0	4.66e-01	88.2%	98.6%
7w6zA01	2.30.42.10	Mainly Beta › Roll › Pdz3 Domain › PDZ domain	0.54	37.0	3.61e-01	87.1%	63.8%
5irbA01	2.60.40.10	Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins	0.51	41.0	3.91e-01	89.4%	92.3%
1l9nA03	2.60.40.10	Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins	0.50	40.0	3.70e-01	89.4%	93.9%

ECOD (51)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3798407	206.1.3.0 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp	0.83	78.0	5.62e-01	100.0%	98.6%
3602296	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.83	78.0	5.51e-01	98.8%	98.2%
3704759	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.83	78.0	5.45e-01	100.0%	89.2%
5042001	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.83	78.0	5.06e-01	100.0%	63.4%
4473535	4095.1.1.2 ↗	alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N	0.82	78.0	5.02e-01	100.0%	63.3%
4012824	206.1.3.0 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp	0.82	77.0	5.43e-01	100.0%	98.7%
4937749	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.82	78.0	5.02e-01	100.0%	62.7%
3182465	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.82	77.0	5.30e-01	100.0%	92.2%
4680450	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.82	76.0	5.44e-01	97.6%	100.0%
4977191	206.1.3.0 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp	0.82	77.0	5.56e-01	100.0%	95.8%
4399570	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.82	76.0	5.43e-01	98.8%	100.0%
3960632	206.1.3.0 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp	0.82	77.0	5.63e-01	100.0%	98.5%
4945406	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.82	77.0	5.58e-01	100.0%	99.5%
4325132	4095.1.1.2 ↗	alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N	0.82	77.0	4.97e-01	100.0%	64.8%
4289141	4095.1.1.2 ↗	alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N	0.82	78.0	4.76e-01	100.0%	48.1%
4683228	4095.1.1.2 ↗	alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N	0.81	77.0	4.82e-01	100.0%	52.5%
4302481	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.81	77.0	5.53e-01	100.0%	99.1%
4098851	4095.1.1.2 ↗	alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N	0.81	77.0	4.96e-01	100.0%	65.7%
4947307	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.81	77.0	4.95e-01	100.0%	61.8%
3315215	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.81	76.0	5.40e-01	100.0%	99.1%
4666907	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.81	76.0	5.57e-01	100.0%	99.0%
3253455	4095.1.1.2 ↗	alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N	0.81	75.0	4.61e-01	100.0%	48.7%
5039677	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.81	76.0	5.42e-01	100.0%	95.0%
4213407	4095.1.1.2 ↗	alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N	0.81	74.0	4.62e-01	97.6%	49.4%
4237088	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.80	76.0	5.57e-01	100.0%	98.0%
4600922	4095.1.1.0 ↗	alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain	0.80	75.0	4.64e-01	100.0%	49.2%
4631711	4095.1.1.3 ↗	alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M	0.80	75.0	4.74e-01	100.0%	53.0%
3633373	4095.1.1.2 ↗	alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N	0.80	75.0	4.55e-01	100.0%	49.5%
4188682	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.80	75.0	5.16e-01	100.0%	92.2%
4982625	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.80	75.0	5.34e-01	100.0%	90.7%
5036153	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.80	70.0	5.15e-01	91.8%	100.0%
4343302	4095.1.1.2 ↗	alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N	0.80	74.0	4.56e-01	100.0%	48.3%
4951306	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.80	75.0	4.64e-01	100.0%	47.7%
4966636	206.1.3.0 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp	0.79	74.0	5.41e-01	100.0%	98.1%
3328725	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.79	74.0	5.49e-01	100.0%	98.0%
4263845	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.79	73.0	5.20e-01	100.0%	96.1%
3378267	4095.1.1.2 ↗	alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N	0.79	73.0	4.52e-01	100.0%	50.7%
3643093	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.79	73.0	5.17e-01	100.0%	95.3%
4000577	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.78	72.0	5.02e-01	100.0%	98.8%
3922871	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.78	72.0	5.15e-01	100.0%	91.3%
5031580	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.74	68.0	5.02e-01	98.8%	100.0%
2559783	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.74	67.0	4.91e-01	96.5%	100.0%
3281941	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.73	66.0	4.97e-01	97.6%	99.5%
3599023	206.1.3.0 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp	0.73	66.0	4.76e-01	98.8%	97.4%
3606912	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.73	66.0	4.61e-01	98.8%	92.2%
3605538	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.72	65.0	4.55e-01	100.0%	92.5%
3598802	206.1.3.0 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp	0.71	64.0	4.44e-01	98.8%	96.3%
3968582	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.70	65.0	4.88e-01	100.0%	98.9%
4943522	206.1.3.23 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › RNA_ligase	0.68	62.0	4.52e-01	100.0%	85.0%
4331294	3325.1.1.1 ↗	a+b two layers › UvrB-binding domain of UvrA › UvrB-binding domain of UvrA › UvrB-binding domain of UvrA › UvrA_inter	0.56	44.0	3.97e-01	85.9%	95.8%
3838180	11.1.1.0 ↗	beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like	0.51	41.0	4.03e-01	89.4%	90.5%

D3 medium residues 47-170

PDB

Domain cluster: rep: DNA_ligase-like_protein__YP_009408099__Eptesipox_virus__1329402__D250-350

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF01068.27 best	DNA_ligase_A_M	77.9	1.20e-21	100.0%	60.8%

CATH (21)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
2cfmA02	3.30.470.30	Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme	0.91	88.0	7.21e-01	100.0%	62.2%
2hivA02	3.30.470.30	Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme	0.87	83.0	6.84e-01	100.0%	60.7%
6p0cA03	3.30.470.30	Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme	0.85	80.0	7.97e-01	98.4%	100.0%
6imjA01	3.30.470.30	Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme	0.84	75.0	6.36e-01	100.0%	61.2%
1vs0A02	3.30.470.30	Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme	0.84	71.0	7.54e-01	98.4%	100.0%
3l2pA03	3.30.470.30	Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme	0.81	75.0	7.66e-01	97.6%	100.0%
6rarI01	3.30.470.30	Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme	0.80	76.0	6.37e-01	100.0%	63.1%
3vnnA00	3.30.470.30	Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme	0.79	70.0	7.10e-01	100.0%	92.7%
1ckmA01	3.30.470.30	Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme	0.78	64.0	5.84e-01	99.2%	67.7%
1a0iA03	3.30.470.30	Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme	0.73	67.0	6.25e-01	98.4%	100.0%
3qwuA02	3.30.470.30	Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme	0.71	58.0	5.04e-01	100.0%	58.3%
1xk5A01	3.30.470.30	Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme	0.71	59.0	4.95e-01	100.0%	54.3%
4ckbA01	3.30.470.140	Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 ›	0.71	48.0	4.22e-01	100.0%	47.8%
2vugA03	3.30.470.30	Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme	0.71	56.0	6.10e-01	97.6%	100.0%
3rtxA01	3.30.470.30	Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme	0.70	65.0	5.77e-01	100.0%	72.1%
4pz6A02	3.30.470.30	Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme	0.68	65.0	5.11e-01	100.0%	54.2%
3kyhC01	3.30.470.30	Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme	0.68	65.0	5.05e-01	100.0%	55.0%
1xdnA02	3.30.470.30	Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme	0.66	60.0	5.53e-01	98.4%	99.4%
1auvA03	3.30.470.20	Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › ATP-grasp fold, B domain	0.65	39.0	4.17e-01	80.6%	68.6%
2rcnA01	2.40.50.140	Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins	0.60	30.0	4.01e-01	71.8%	95.1%
3d0fA01	2.40.50.140	Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins	0.52	31.0	3.79e-01	97.6%	100.0%

ECOD (93)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4289141	4095.1.1.2 ↗	alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N	0.92	87.0	5.77e-01	100.0%	29.0%
5036153	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.92	87.0	7.22e-01	100.0%	62.6%
4960010	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.91	87.0	7.02e-01	100.0%	57.2%
4947392	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.91	86.0	7.02e-01	100.0%	58.1%
5076593	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.91	85.0	7.17e-01	100.0%	63.7%
4325132	4095.1.1.2 ↗	alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N	0.91	88.0	6.14e-01	100.0%	39.7%
5066075	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.91	87.0	7.25e-01	100.0%	64.1%
4951306	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.91	84.0	5.60e-01	100.0%	28.9%
3602296	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.90	87.0	6.88e-01	100.0%	63.1%
5042001	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.90	87.0	6.13e-01	100.0%	38.8%
4935888	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.90	87.0	6.08e-01	100.0%	37.3%
4945406	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.90	87.0	7.04e-01	100.0%	59.5%
4966636	206.1.3.0 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp	0.90	87.0	7.02e-01	100.0%	60.5%
4977191	206.1.3.0 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp	0.90	86.0	6.96e-01	100.0%	58.1%
4631711	4095.1.1.3 ↗	alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M	0.90	84.0	5.71e-01	100.0%	31.4%
4937749	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.90	86.0	6.07e-01	100.0%	38.2%
4237088	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.90	80.0	6.57e-01	100.0%	57.0%
5083927	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.90	86.0	6.88e-01	100.0%	67.0%
4045857	4095.1.1.2 ↗	alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N	0.90	86.0	5.68e-01	100.0%	30.2%
4473535	4095.1.1.2 ↗	alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N	0.90	86.0	6.04e-01	100.0%	38.2%
4600922	4095.1.1.0 ↗	alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain	0.89	86.0	5.67e-01	100.0%	29.6%
4399570	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.89	85.0	6.78e-01	100.0%	56.9%
5016269	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.89	86.0	5.96e-01	100.0%	40.6%
4098851	4095.1.1.2 ↗	alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N	0.89	86.0	6.00e-01	100.0%	41.8%
4213407	4095.1.1.2 ↗	alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N	0.89	84.0	5.60e-01	100.0%	30.1%
3962528	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.89	84.0	6.97e-01	100.0%	61.5%
4982625	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.89	85.0	6.74e-01	100.0%	55.6%
3960632	206.1.3.0 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp	0.89	83.0	6.80e-01	100.0%	59.0%
4666907	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.89	83.0	6.85e-01	100.0%	59.5%
4683228	4095.1.1.2 ↗	alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N	0.89	83.0	5.61e-01	100.0%	31.4%
4947307	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.88	84.0	5.93e-01	100.0%	37.3%
4495705	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.88	84.0	6.68e-01	100.0%	64.4%
3281941	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.88	84.0	7.02e-01	100.0%	63.6%
4047933	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.88	84.0	6.95e-01	100.0%	62.0%
4056196	4095.1.1.2 ↗	alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N	0.88	84.0	5.52e-01	100.0%	28.4%
3968582	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.88	80.0	6.78e-01	100.0%	62.1%
5039677	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.88	84.0	6.71e-01	100.0%	57.3%
5031580	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.88	84.0	6.93e-01	100.0%	62.5%
4263845	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.87	84.0	6.59e-01	100.0%	60.4%
4302481	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.87	84.0	6.76e-01	100.0%	62.3%
3315215	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.87	83.0	6.56e-01	100.0%	58.3%
3798407	206.1.3.0 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp	0.87	83.0	6.69e-01	100.0%	59.1%
3643093	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.87	83.0	6.48e-01	100.0%	53.6%
4012824	206.1.3.0 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp	0.87	83.0	6.48e-01	100.0%	62.6%
3182465	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.86	83.0	6.29e-01	100.0%	58.8%
3704759	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.86	82.0	6.41e-01	100.0%	53.8%
3253455	4095.1.1.2 ↗	alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N	0.85	82.0	5.35e-01	100.0%	29.8%
4914243	206.1.3.116 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M, DNA_ligase_A_C	0.85	81.0	6.69e-01	100.0%	62.4%
3288874	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.85	73.0	6.15e-01	100.0%	56.9%
3378267	4095.1.1.2 ↗	alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N	0.85	81.0	5.33e-01	100.0%	28.4%
4680450	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.85	81.0	6.56e-01	100.0%	63.3%
4995719	206.1.3.0 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp	0.85	70.0	6.17e-01	100.0%	61.7%
3606912	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.84	80.0	6.12e-01	100.0%	53.3%
4188682	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.84	80.0	6.13e-01	100.0%	57.3%
3697249	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.84	80.0	6.14e-01	100.0%	58.0%
3633373	4095.1.1.2 ↗	alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N	0.84	80.0	5.20e-01	100.0%	30.8%
3194296	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.84	79.0	5.94e-01	100.0%	53.8%
3434631	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.84	64.0	6.35e-01	79.0%	82.2%
3599023	206.1.3.0 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp	0.83	79.0	6.29e-01	100.0%	57.0%
3605538	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.83	79.0	6.00e-01	100.0%	58.9%
3476026	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.83	78.0	5.92e-01	100.0%	59.3%
3581071	4095.1.1.2 ↗	alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N	0.83	79.0	5.22e-01	100.0%	28.9%
3799247	206.1.3.0 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp	0.83	78.0	5.95e-01	100.0%	47.3%
3939304	4095.1.1.3 ↗	alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M	0.83	79.0	5.18e-01	100.0%	31.2%
4343302	4095.1.1.2 ↗	alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N	0.83	79.0	5.18e-01	100.0%	29.7%
3795817	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.82	78.0	5.88e-01	100.0%	46.4%
4000577	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.82	78.0	5.97e-01	100.0%	52.9%
3922871	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.82	78.0	6.18e-01	100.0%	56.5%
3397951	4095.1.1.2 ↗	alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N	0.82	78.0	5.05e-01	100.0%	27.4%
3513779	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.82	78.0	6.28e-01	100.0%	59.6%
3580961	4095.1.1.3 ↗	alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M	0.82	77.0	5.17e-01	100.0%	32.1%
3237928	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.81	77.0	5.97e-01	100.0%	57.6%
3927529	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.81	77.0	6.00e-01	100.0%	57.9%
2559783	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.80	76.0	6.29e-01	100.0%	61.2%
1837660	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.79	70.0	7.10e-01	100.0%	92.7%
7118	206.1.3.4 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › mRNA_cap_enzyme	0.78	65.0	5.11e-01	100.0%	46.5%
3701347	2.1.1.0 ↗	beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein	0.76	65.0	4.55e-01	100.0%	32.4%
3704365	206.1.3.0 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp	0.76	65.0	5.24e-01	100.0%	51.2%
3595473	206.1.3.0 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp	0.75	64.0	5.13e-01	100.0%	50.0%
3397601	206.1.3.30 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › SPN1_m3Gcap_bd	0.74	60.0	4.66e-01	100.0%	43.3%
3500957	206.1.3.4 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › mRNA_cap_enzyme	0.72	65.0	5.02e-01	100.0%	47.2%
5070559	206.1.3.23 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › RNA_ligase	0.72	57.0	4.53e-01	100.0%	43.3%
3872907	206.1.3.0 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp	0.70	58.0	4.53e-01	100.0%	43.6%
3894770	206.1.3.4 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › mRNA_cap_enzyme	0.70	58.0	4.56e-01	100.0%	44.0%
4983231	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.69	65.0	5.43e-01	100.0%	63.0%
7119	206.1.3.4 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › mRNA_cap_enzyme	0.69	66.0	5.12e-01	100.0%	53.1%
5024218	206.1.3.23 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › RNA_ligase	0.69	65.0	4.68e-01	100.0%	54.7%
1298640	206.1.3.4 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › mRNA_cap_enzyme	0.69	65.0	5.10e-01	100.0%	53.6%
3939998	206.1.3.0 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp	0.65	55.0	4.30e-01	100.0%	43.5%
3997608	206.1.3.0 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp	0.64	55.0	4.21e-01	100.0%	41.0%
3578637	206.1.3.0 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp	0.63	55.0	4.16e-01	100.0%	40.0%
3476642	206.1.3.0 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp	0.63	57.0	4.56e-01	100.0%	50.6%
3240894	206.1.3.0 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp	0.62	57.0	4.40e-01	100.0%	46.8%

D4 medium residues 230-342

PDB

Domain cluster: rep: DNA_ligase_-2-__YP_010377156__Monkeypox_virus__10244__D413-557

CATH (12)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
6p0cA04	2.40.50.140	Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins	0.88	71.0	6.38e-01	83.2%	95.2%
2hivA03	2.40.50.140	Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins	0.88	70.0	6.23e-01	83.2%	90.2%
2cfmA03	2.40.50.140	Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins	0.87	69.0	6.39e-01	83.2%	86.4%
6nhxA02	2.40.50.140	Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins	0.84	64.0	6.37e-01	78.8%	97.4%
2xgtB01	2.40.50.140	Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins	0.62	46.0	4.80e-01	97.3%	86.1%
1u5kA01	2.40.50.140	Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins	0.62	42.0	4.73e-01	98.2%	95.1%
6l4qB01	2.40.50.140	Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins	0.61	43.0	4.09e-01	72.6%	61.5%
2i5hA01	2.40.50.140	Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins	0.59	37.0	4.53e-01	88.5%	100.0%
1eovA01	2.40.50.140	Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins	0.58	45.0	4.29e-01	98.2%	70.9%
3jtzA00	3.30.160.390	Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Integrase, DNA-binding domain	0.54	28.0	3.28e-01	74.3%	70.1%
3doaA01	2.30.310.10	Mainly Beta › Roll › ibrinogen binding protein from staphylococcus aureus fold › ibrinogen binding protein from staphylococcus aureus domain	0.53	37.0	3.31e-01	70.8%	54.9%
3h0gH00	2.40.50.140	Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins	0.51	39.0	3.86e-01	82.3%	85.5%

ECOD (25)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4947393	2.1.1.31 ↗	beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › DNA_ligase_A_C	0.90	69.0	6.89e-01	78.8%	100.0%
5076594	2.1.1.31 ↗	beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › DNA_ligase_A_C	0.89	70.0	6.77e-01	81.4%	96.0%
3621122	2.1.1.31 ↗	beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › DNA_ligase_A_C	0.88	70.0	6.57e-01	83.2%	94.1%
4455042	2.1.1.31 ↗	beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › DNA_ligase_A_C	0.86	69.0	6.36e-01	83.2%	85.0%
3222306	2.1.1.0 ↗	beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein	0.86	69.0	6.40e-01	83.2%	95.6%
4001812	2.1.1.0 ↗	beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein	0.85	68.0	6.28e-01	83.2%	91.4%
4995720	2.1.1.31 ↗	beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › DNA_ligase_A_C	0.83	64.0	6.01e-01	79.6%	99.3%
3600258	2.1.1.28 ↗	beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › mRNA_cap_C	0.74	58.0	6.21e-01	82.3%	96.0%
3707855	2.1.1.0 ↗	beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein	0.70	55.0	5.40e-01	81.4%	79.2%
3230022	2.1.1.0 ↗	beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein	0.69	42.0	5.10e-01	72.6%	97.1%
3243150	2.1.1.0 ↗	beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein	0.67	43.0	5.02e-01	99.1%	96.0%
3277380	2.1.1.0 ↗	beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein	0.67	48.0	4.95e-01	90.3%	79.0%
4278743	2.1.1.15 ↗	beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › tRNA_anti-codon	0.66	45.0	4.63e-01	71.7%	72.7%
3590786	2.1.1.15 ↗	beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › tRNA_anti-codon	0.65	45.0	4.62e-01	71.7%	74.5%
4032340	2.1.1.15 ↗	beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › tRNA_anti-codon	0.65	45.0	4.63e-01	71.7%	76.2%
3387410	2.1.1.0 ↗	beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein	0.65	45.0	4.53e-01	71.7%	73.9%
4238204	2.1.1.15 ↗	beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › tRNA_anti-codon	0.63	44.0	4.57e-01	71.7%	77.1%
3388887	4.8.1.2 ↗	beta barrels › SH3 › Chromo domain-like › Chromo domain-like › Chromo_shadow	0.63	31.0	3.95e-01	94.7%	81.5%
4528707	2.1.1.15 ↗	beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › tRNA_anti-codon	0.62	43.0	4.41e-01	75.2%	73.6%
4078426	2.1.1.15 ↗	beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › tRNA_anti-codon	0.62	46.0	4.52e-01	98.2%	73.3%
3959920	2.1.1.15 ↗	beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › tRNA_anti-codon	0.61	42.0	4.23e-01	72.6%	69.6%
4369732	2.1.1.15 ↗	beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › tRNA_anti-codon	0.61	42.0	4.33e-01	71.7%	74.5%
3282699	2.1.1.15 ↗	beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › tRNA_anti-codon	0.59	43.0	4.30e-01	100.0%	73.9%
4592273	2.1.1.84 ↗	beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › Prot_ATP_ID_OB_N	0.57	34.0	3.41e-01	71.7%	55.0%
5042874	2.1.1.0 ↗	beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein	0.51	40.0	4.04e-01	100.0%	83.5%

D5 medium residues 374-444_500-590

PDB

Domain cluster: representative

CATH (10)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4akgA14	1.20.1280.160	Mainly Alpha › Up-down Bundle › Monooxygenase ›	0.58	27.0	3.33e-01	97.5%	67.0%
1u7lA02	1.20.1460.10	Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › subunit c (vma5p) of the yeast v-atpase, domain 2	0.54	31.0	3.04e-01	90.7%	49.7%
6vvoC03	1.20.272.10	Mainly Alpha › Up-down Bundle › Zinc Finger, Delta Prime; domain 3 ›	0.53	30.0	3.89e-01	74.1%	98.9%
3fbzA01	1.20.58.800	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.53	29.0	3.56e-01	72.2%	83.3%
1owlA02	1.25.40.80	Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat ›	0.51	33.0	3.75e-01	98.8%	84.6%
5cbgA00	1.10.287.70	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.51	32.0	3.95e-01	79.0%	100.0%
6rxaA01	1.10.40.30	Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase Protein R1; domain 1 › Fumarase/aspartase (C-terminal domain)	0.51	29.0	3.68e-01	71.6%	100.0%
2lyiA01	1.10.274.60	Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Spidroin, repetitive domain	0.51	35.0	3.68e-01	83.3%	76.4%
2mqaA00	1.10.274.60	Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Spidroin, repetitive domain	0.50	36.0	4.02e-01	85.2%	96.0%
3cr3A00	1.25.40.340	Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › DhaL domain	0.50	39.0	3.68e-01	80.9%	100.0%

ECOD (5)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3587291	628.1.1.1 ↗	alpha bundles › Fatty acid responsive transcription factor FadR, C-terminal domain › Fatty acid responsive transcription factor FadR, C-terminal domain › Fatty acid responsive transcription factor FadR, C-terminal domain › FCD	0.56	31.0	3.27e-01	93.8%	57.3%
4634565	191.1.1.0 ↗	alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain	0.55	31.0	3.39e-01	71.6%	65.5%
3602521	4323.1.1.0 ↗	alpha bundles › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C	0.54	29.0	3.00e-01	92.6%	51.9%
5012706	605.1.1.0 ↗	alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase	0.53	32.0	3.71e-01	77.8%	82.6%
4452139	131.1.1.3 ↗	alpha complex topology › PDEase-like › HD-domain/PDEase-like › HD-domain/PDEase-like › HD	0.51	34.0	3.58e-01	77.2%	72.7%

D6 medium residues 445-499

PDB

Domain cluster: representative

CATH (42)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
1q9uA00	3.30.310.70	Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › TT1751-like domain	0.70	57.0	4.45e-01	94.5%	77.3%
2lvlA01	2.170.150.60	Mainly Beta › Beta Complex › Metal Binding Protein, Guanine Nucleotide Exchange Factor; Chain A ›	0.65	54.0	4.42e-01	98.2%	100.0%
1dl5A02	3.55.20.10	Alpha Beta › 3-Layer(bab) Sandwich › Protein-l-isoaspartate O-methyltransferase; Chain: A, domain 2 › Protein-L-isoaspartyl O-methyltransferase, C-terminal domain	0.65	49.0	3.92e-01	83.6%	45.7%
1v5vA02	3.30.70.1400	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Aminomethyltransferase beta-barrel domains	0.65	50.0	4.31e-01	87.3%	70.7%
3nvnA00	2.130.10.10	Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase	0.65	45.0	2.71e-01	72.7%	19.6%
2f09A00	2.40.128.200	Mainly Beta › Beta Barrel › Lipocalin › C-type lysozyme inhibitor	0.63	46.0	4.11e-01	80.0%	70.7%
4tr6A01	3.10.150.10	Alpha Beta › Roll › DNA Polymerase III; Chain A, domain 2 › DNA Polymerase III, subunit A, domain 2	0.63	46.0	3.26e-01	80.0%	71.7%
2d0bA01	3.30.310.10	Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › TATA-Binding Protein	0.62	48.0	4.27e-01	90.9%	80.9%
1f49A05	2.70.98.10	Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 ›	0.62	44.0	2.86e-01	78.2%	90.3%
1g3pA01	2.30.27.10	Mainly Beta › Roll › Phage FD Coat Protein, Membrane penetration domain › Phage FD Coat Protein,Membrane penetration domain	0.62	47.0	4.14e-01	85.5%	67.0%
3vn5A01	3.30.310.10	Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › TATA-Binding Protein	0.62	46.0	4.34e-01	83.6%	82.6%
2x9aA00	2.30.27.10	Mainly Beta › Roll › Phage FD Coat Protein, Membrane penetration domain › Phage FD Coat Protein,Membrane penetration domain	0.61	46.0	4.52e-01	85.5%	91.8%
1ni5A02	1.20.59.20	Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A ›	0.61	44.0	3.86e-01	78.2%	87.2%
3t0pA01	3.10.150.10	Alpha Beta › Roll › DNA Polymerase III; Chain A, domain 2 › DNA Polymerase III, subunit A, domain 2	0.61	47.0	3.34e-01	85.5%	87.2%
3e5zA00	2.120.10.30	Mainly Beta › 6 Propeller › Neuraminidase › TolB, C-terminal domain	0.60	49.0	3.15e-01	92.7%	96.9%
1smpI00	2.40.128.10	Mainly Beta › Beta Barrel › Lipocalin ›	0.60	41.0	3.41e-01	72.7%	79.0%
3u9sE04	3.30.700.40	Alpha Beta › 2-Layer Sandwich › Glycoprotein, Type 4 Pilin ›	0.60	51.0	3.93e-01	96.4%	52.8%
1ei5A02	2.40.128.50	Mainly Beta › Beta Barrel › Lipocalin ›	0.59	42.0	3.81e-01	80.0%	74.4%
7ufsA01	2.70.98.30	Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › Golgi alpha-mannosidase II; domain 4	0.58	42.0	2.79e-01	80.0%	88.5%
4lqzA00	2.40.128.570	Mainly Beta › Beta Barrel › Lipocalin › Protein of unknown function DUF4909	0.58	40.0	3.15e-01	74.5%	83.2%
4py5A01	3.30.310.10	Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › TATA-Binding Protein	0.57	40.0	3.82e-01	78.2%	75.0%
1qhuA01	2.110.10.10	Mainly Beta › 4 Propeller › Hemopexin › Hemopexin-like domain	0.57	38.0	2.77e-01	70.9%	23.5%
7dd9A02	2.70.98.30	Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › Golgi alpha-mannosidase II; domain 4	0.57	46.0	3.13e-01	98.2%	67.3%
2oqbA00	2.30.29.30	Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)	0.56	47.0	3.85e-01	96.4%	78.7%
3hkzG00	2.40.50.140	Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins	0.56	38.0	3.14e-01	72.7%	70.8%
1hxnA00	2.110.10.10	Mainly Beta › 4 Propeller › Hemopexin › Hemopexin-like domain	0.56	39.0	2.70e-01	74.5%	22.4%
4czxA00	2.130.10.10	Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase	0.56	45.0	2.94e-01	100.0%	98.1%
3h41A02	2.30.30.40	Mainly Beta › Roll › SH3 type barrels. › SH3 Domains	0.56	47.0	4.38e-01	92.7%	76.5%
5f7uA02	2.60.40.1760	Mainly Beta › Sandwich › Immunoglobulin-like › glycosyl hydrolase (family 31)	0.56	40.0	2.72e-01	78.2%	65.0%
1vpkA02	3.10.150.10	Alpha Beta › Roll › DNA Polymerase III; Chain A, domain 2 › DNA Polymerase III, subunit A, domain 2	0.56	39.0	3.06e-01	76.4%	92.2%
6xofA01	2.60.120.200	Mainly Beta › Sandwich › Jelly Rolls ›	0.55	42.0	2.79e-01	85.5%	83.0%
2lydA00	2.30.29.30	Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)	0.55	46.0	3.51e-01	96.4%	63.4%
5f1sA02	2.60.40.10	Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins	0.54	42.0	3.54e-01	89.1%	85.3%
5d2lE01	2.60.40.10	Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins	0.54	42.0	3.46e-01	89.1%	85.2%
2cocA01	2.30.29.30	Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)	0.53	44.0	3.67e-01	94.5%	81.0%
4qa8A00	2.50.20.20	Mainly Beta › Clam › outer membrane lipoprotein receptor (LolB), chain A ›	0.52	42.0	2.97e-01	98.2%	88.1%
4lxqB00	3.40.50.12230	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold ›	0.52	43.0	2.82e-01	96.4%	27.0%
3rkgA01	2.40.128.330	Mainly Beta › Beta Barrel › Lipocalin ›	0.52	42.0	3.66e-01	96.4%	91.5%
1w1hD00	2.30.29.30	Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)	0.51	43.0	3.29e-01	96.4%	78.8%
3d8kD00	3.60.40.10	Alpha Beta › 4-Layer Sandwich › Phosphatase 2c; domain 1 › PPM-type phosphatase domain	0.51	41.0	2.57e-01	94.5%	58.1%
1m3qA01	3.30.310.40	Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein ›	0.51	39.0	3.53e-01	96.4%	86.5%
3igfA02	2.60.40.790	Mainly Beta › Sandwich › Immunoglobulin-like ›	0.50	38.0	3.51e-01	90.9%	62.2%

ECOD (73)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
2475320	2002.1.1.0 ↗	a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels	0.71	48.0	2.72e-01	70.9%	13.2%
4021196	270.1.1.0 ↗	beta barrels › FMT C-terminal domain-like › FMT C-terminal domain-related › FMT C-terminal domain-related	0.67	57.0	4.34e-01	98.2%	57.0%
3216869	6129.1.1.1 ↗	beta barrels › Repulsive guidance molecule (RGM) family › Repulsive guidance molecule (RGM) family › Repulsive guidance molecule (RGM) family › VWD	0.66	54.0	3.77e-01	94.5%	66.7%
4534097	2004.1.1.29 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD	0.65	58.0	3.35e-01	100.0%	22.4%
6346	331.8.1.1 ↗	a+b two layers › TBP-like › Protein-L-isoaspartyl O-methyltransferase, C-terminal domain › Protein-L-isoaspartyl O-methyltransferase, C-terminal domain › PIMT_C	0.65	49.0	4.05e-01	83.6%	51.0%
5028450	331.1.1.6 ↗	a+b two layers › TBP-like › TATA-box binding protein-like › TATA-box binding protein-like › DUF3378	0.65	49.0	4.57e-01	83.6%	84.3%
5023940	4312.1.1.0 ↗	a+b two layers › RelE-like › RelE-like › RelE-like	0.64	46.0	4.34e-01	80.0%	87.1%
5012894	331.1.1.0 ↗	a+b two layers › TBP-like › TATA-box binding protein-like › TATA-box binding protein-like	0.63	49.0	4.51e-01	87.3%	74.7%
3212893	5.1.3.57 ↗	beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › IKI3	0.63	43.0	2.67e-01	72.7%	21.7%
4944418	331.1.1.0 ↗	a+b two layers › TBP-like › TATA-box binding protein-like › TATA-box binding protein-like	0.63	50.0	4.60e-01	92.7%	84.0%
3966450	3794.1.1.0 ↗	a+b two layers › Methylcrotonyl-CoA carboxylase alpha-subunit BT domain-related › Methylcrotonyl-CoA carboxylase alpha-subunit BT domain-related › Barrel domain in methylcrotonyl-CoA carboxylase alpha-subunit	0.62	55.0	4.26e-01	98.2%	60.0%
3969266	3018.1.1.1 ↗	a+b two layers › MesJ substrate recognition domain-like › MesJ substrate recognition domain-like › MesJ substrate recognition domain-like › TilS	0.61	46.0	3.85e-01	81.8%	76.0%
4388719	3018.1.1.1 ↗	a+b two layers › MesJ substrate recognition domain-like › MesJ substrate recognition domain-like › MesJ substrate recognition domain-like › TilS	0.61	45.0	3.88e-01	78.2%	83.3%
4429100	3018.1.1.1 ↗	a+b two layers › MesJ substrate recognition domain-like › MesJ substrate recognition domain-like › MesJ substrate recognition domain-like › TilS	0.61	45.0	3.87e-01	80.0%	84.4%
146734	881.3.1.1 ↗	a+b three layers › Mog1p/PsbP-like › Outer membrane-associated lipoprotein TP0453 › Outer membrane-associated lipoprotein TP0453 › TP0453	0.61	51.0	3.38e-01	98.2%	95.2%
4943589	331.1.1.28 ↗	a+b two layers › TBP-like › TATA-box binding protein-like › TATA-box binding protein-like › Fer4_7	0.61	49.0	3.61e-01	92.7%	40.6%
1124186	3794.1.1.2 ↗	a+b two layers › Methylcrotonyl-CoA carboxylase alpha-subunit BT domain-related › Methylcrotonyl-CoA carboxylase alpha-subunit BT domain-related › Barrel domain in methylcrotonyl-CoA carboxylase alpha-subunit › MCC_alpha_BT	0.61	54.0	4.22e-01	100.0%	57.6%
4526691	6043.1.1.0 ↗	a+b two layers › yfeY-like › yfeY-like › yfeY-like	0.60	43.0	4.16e-01	80.0%	78.5%
3266341	4121.1.1.2 ↗	a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › MRS2-like	0.60	47.0	3.06e-01	87.3%	33.6%
4243044	6129.1.1.1 ↗	beta barrels › Repulsive guidance molecule (RGM) family › Repulsive guidance molecule (RGM) family › Repulsive guidance molecule (RGM) family › VWD	0.59	50.0	3.64e-01	100.0%	82.4%
5004885	2003.6.1.4 ↗	a/b three-layered sandwiches › Rossmann-like › Ribokinase-like › Ribokinase-like › ADP_PFK_GK	0.59	49.0	2.91e-01	94.5%	27.0%
4958012	331.1.1.0 ↗	a+b two layers › TBP-like › TATA-box binding protein-like › TATA-box binding protein-like	0.59	45.0	4.13e-01	85.5%	76.0%
5000881	223.2.1.0 ↗	a+b three layers › Profilin-like › profilin-like › profilin-like	0.59	46.0	3.47e-01	89.1%	58.1%
3593007	331.10.1.0 ↗	a+b two layers › TBP-like › S-adenosylmethionine decarboxylase-related › S-adenosylmethionine decarboxylase	0.59	46.0	2.98e-01	90.9%	33.2%
1945658	331.10.1.1 ↗	a+b two layers › TBP-like › S-adenosylmethionine decarboxylase-related › S-adenosylmethionine decarboxylase › SAM_decarbox	0.58	46.0	2.99e-01	90.9%	33.6%
3783819	331.10.1.1 ↗	a+b two layers › TBP-like › S-adenosylmethionine decarboxylase-related › S-adenosylmethionine decarboxylase › SAM_decarbox	0.58	46.0	2.84e-01	90.9%	41.1%
4992197	205.1.1.16 ↗	a+b two layers › 4Fe-4S ferredoxin › 4Fe-4S ferredoxin › 4Fe-4S ferredoxin › Fer4_7	0.58	42.0	3.34e-01	80.0%	43.2%
4152362	881.4.1.2 ↗	a+b three layers › Mog1p/PsbP-like › C-terminal domain in sigma-E factor regulatory protein rseB › C-terminal domain in sigma-E factor regulatory protein rseB › DUF4367	0.58	46.0	3.87e-01	96.4%	73.6%
3228484	207.1.1.81 ↗	beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › FTH	0.58	42.0	2.78e-01	80.0%	22.4%
5060936	331.1.1.0 ↗	a+b two layers › TBP-like › TATA-box binding protein-like › TATA-box binding protein-like	0.57	46.0	4.00e-01	92.7%	70.0%
3639208	331.10.1.1 ↗	a+b two layers › TBP-like › S-adenosylmethionine decarboxylase-related › S-adenosylmethionine decarboxylase › SAM_decarbox	0.57	45.0	2.80e-01	90.9%	45.3%
5002867	331.1.1.0 ↗	a+b two layers › TBP-like › TATA-box binding protein-like › TATA-box binding protein-like	0.57	44.0	3.83e-01	87.3%	71.1%
4948221	331.1.1.29 ↗	a+b two layers › TBP-like › TATA-box binding protein-like › TATA-box binding protein-like › Fer4_10	0.57	45.0	4.00e-01	90.9%	77.6%
4132512	331.10.1.1 ↗	a+b two layers › TBP-like › S-adenosylmethionine decarboxylase-related › S-adenosylmethionine decarboxylase › SAM_decarbox	0.57	44.0	2.79e-01	90.9%	39.7%
3599120	331.10.1.0 ↗	a+b two layers › TBP-like › S-adenosylmethionine decarboxylase-related › S-adenosylmethionine decarboxylase	0.57	44.0	2.79e-01	90.9%	40.0%
4937221	331.1.1.0 ↗	a+b two layers › TBP-like › TATA-box binding protein-like › TATA-box binding protein-like	0.57	44.0	4.15e-01	94.5%	77.3%
5059518	11.1.1.0 ↗	beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like	0.57	44.0	3.57e-01	85.5%	50.0%
4031431	331.1.1.0 ↗	a+b two layers › TBP-like › TATA-box binding protein-like › TATA-box binding protein-like	0.57	43.0	4.14e-01	87.3%	87.7%
3736515	73.1.1.0 ↗	beta sandwiches › SMAD/FHA domain › SMAD/FHA domain › SMAD/FHA domain	0.56	47.0	3.29e-01	92.7%	84.0%
3961809	9.11.1.1 ↗	beta barrels › Lipocalins/Streptavidin › YdhA-like › YdhA-like › MliC	0.56	40.0	3.68e-01	80.0%	78.8%
4024428	4121.1.1.2 ↗	a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › MRS2-like	0.56	47.0	3.01e-01	96.4%	33.0%
5061645	4312.1.1.15 ↗	a+b two layers › RelE-like › RelE-like › RelE-like › DUF4258	0.56	42.0	4.11e-01	85.5%	90.5%
3898349	4121.1.1.2 ↗	a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › MRS2-like	0.56	46.0	3.12e-01	96.4%	32.3%
3952440	881.1.1.8 ↗	a+b three layers › Mog1p/PsbP-like › Mog1p/PsbP-like › Mog1p/PsbP-like › PknH_C	0.56	45.0	3.33e-01	96.4%	82.2%
3606549	9.1.1.4 ↗	beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins › META	0.56	37.0	3.11e-01	70.9%	89.0%
3973141	331.2.1.0 ↗	a+b two layers › TBP-like › Phosphoglucomutase, C-terminal domain › Phosphoglucomutase, C-terminal domain	0.56	42.0	3.70e-01	87.3%	80.0%
3705308	9.1.1.4 ↗	beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins › META	0.55	44.0	3.55e-01	90.9%	93.9%
4870707	4121.1.1.2 ↗	a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › MRS2-like	0.55	46.0	3.09e-01	96.4%	32.3%
3712908	9.1.1.4 ↗	beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins › META	0.55	43.0	3.50e-01	87.3%	96.3%
3605590	9.1.1.4 ↗	beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins › META	0.55	42.0	3.37e-01	83.6%	94.5%
4242897	5.1.4.61 ↗	beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › PAN2_N	0.55	44.0	2.79e-01	98.2%	84.4%
3948079	9.1.1.4 ↗	beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins › META	0.55	37.0	3.00e-01	70.9%	84.2%
3266624	9.2.1.0 ↗	beta barrels › Lipocalins/Streptavidin › Avidin/Streptavidin › Avidin/Streptavidin	0.55	39.0	3.32e-01	81.8%	80.0%
3814929	5.1.5.86 ↗	beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed › Kelch_1	0.55	43.0	2.77e-01	89.1%	86.4%
3594594	3794.1.1.0 ↗	a+b two layers › Methylcrotonyl-CoA carboxylase alpha-subunit BT domain-related › Methylcrotonyl-CoA carboxylase alpha-subunit BT domain-related › Barrel domain in methylcrotonyl-CoA carboxylase alpha-subunit	0.55	43.0	3.30e-01	87.3%	69.2%
4162390	4121.1.1.2 ↗	a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › MRS2-like	0.54	45.0	2.95e-01	98.2%	31.4%
5059893	11.1.1.0 ↗	beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like	0.54	43.0	3.47e-01	87.3%	52.7%
3281771	9.1.1.4 ↗	beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins › META	0.54	42.0	3.46e-01	89.1%	93.6%
4874849	244.1.1.4 ↗	a+b two layers › FAD-linked reductases, C-terminal domain-like › FAD-linked reductases-C › FAD-linked reductases-C › DAO	0.54	44.0	4.51e-01	90.9%	96.2%
5028597	331.1.1.0 ↗	a+b two layers › TBP-like › TATA-box binding protein-like › TATA-box binding protein-like	0.54	42.0	3.82e-01	90.9%	70.0%
4982639	331.1.1.0 ↗	a+b two layers › TBP-like › TATA-box binding protein-like › TATA-box binding protein-like	0.54	41.0	3.46e-01	92.7%	53.9%
4079675	4959.1.1.1 ↗	a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_3	0.54	44.0	3.71e-01	100.0%	72.5%
3631068	206.1.1.56 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › DUF2252	0.54	45.0	2.72e-01	98.2%	23.2%
3281774	9.1.1.4 ↗	beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins › META	0.53	39.0	3.24e-01	81.8%	96.4%
3416069	331.1.1.0 ↗	a+b two layers › TBP-like › TATA-box binding protein-like › TATA-box binding protein-like	0.53	39.0	3.66e-01	81.8%	75.7%
3236067	207.1.1.81 ↗	beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › FTH	0.53	39.0	2.70e-01	85.5%	34.2%
3600529	9.1.1.0 ↗	beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins	0.53	35.0	3.00e-01	70.9%	88.6%
4849749	4959.1.1.0 ↗	a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit	0.52	42.0	3.88e-01	94.5%	78.7%
4985658	331.1.1.0 ↗	a+b two layers › TBP-like › TATA-box binding protein-like › TATA-box binding protein-like	0.51	41.0	3.76e-01	100.0%	72.9%
3614740	3794.1.1.0 ↗	a+b two layers › Methylcrotonyl-CoA carboxylase alpha-subunit BT domain-related › Methylcrotonyl-CoA carboxylase alpha-subunit BT domain-related › Barrel domain in methylcrotonyl-CoA carboxylase alpha-subunit	0.51	43.0	3.33e-01	96.4%	65.4%
3218686	211.1.1.0 ↗	a+b two layers › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase	0.51	43.0	3.59e-01	98.2%	87.0%
5058484	331.1.1.0 ↗	a+b two layers › TBP-like › TATA-box binding protein-like › TATA-box binding protein-like	0.50	37.0	3.58e-01	87.3%	81.4%
3511291	11.1.1.97 ↗	beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › I-set	0.50	39.0	3.27e-01	89.1%	84.8%

D7 medium residues 741-796

PDB

D8 medium residues 942-1047

PDB

D9 medium residues 1111-1207

PDB

Domain cluster: representative

CATH (49)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
2iruA02	3.30.70.3300	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits ›	0.84	78.0	6.87e-01	100.0%	73.2%
2faoA01	3.90.920.10	Alpha Beta › Alpha-Beta Complex › DNA primase, PRIM domain › DNA primase, PRIM domain	0.79	73.0	5.15e-01	100.0%	35.8%
4kyzA00	3.30.70.600	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10	0.75	52.0	4.34e-01	89.7%	41.9%
2kl8A00	3.30.70.600	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10	0.72	49.0	5.21e-01	88.7%	81.2%
3aqoA01	3.30.70.3400	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits ›	0.71	50.0	5.40e-01	90.7%	87.5%
4mt1A07	3.30.70.1440	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Multidrug efflux transporter AcrB pore domain	0.70	55.0	5.47e-01	97.9%	79.4%
2kjwA00	3.30.70.60	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S6/Translation elongation factor EF1B	0.69	50.0	5.09e-01	88.7%	77.1%
2ebbA00	3.30.1360.20	Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › Transcriptional coactivator/pterin dehydratase	0.69	46.0	4.63e-01	70.1%	68.8%
1q8bA00	3.30.70.100	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits ›	0.68	51.0	5.20e-01	95.9%	81.7%
5wm1A02	3.30.70.270	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain	0.67	54.0	5.20e-01	94.8%	77.1%
2cveA02	3.30.70.240	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits ›	0.67	41.0	4.68e-01	85.6%	87.9%
4v1al00	3.30.780.10	Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor Eif1 › SUI1-like domain	0.66	39.0	3.52e-01	73.2%	41.4%
1yz7A02	3.30.70.1130	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › EIF_2_alpha	0.66	50.0	5.23e-01	91.8%	87.8%
2mcqA01	3.30.300.90	Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › BolA-like	0.66	46.0	5.12e-01	83.5%	94.7%
3ezuA02	3.30.70.270	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain	0.66	57.0	4.93e-01	94.8%	69.6%
5w2fA01	3.30.780.10	Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor Eif1 › SUI1-like domain	0.65	44.0	4.65e-01	83.5%	77.9%
2b4vA02	3.30.460.50	Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 ›	0.64	50.0	4.70e-01	84.5%	97.5%
2f5gA00	3.30.70.1290	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Transposase IS200-like	0.63	51.0	4.71e-01	97.9%	66.9%
3kewB02	3.30.980.10	Alpha Beta › 2-Layer Sandwich › Threonyl-tRNA Synthetase; Chain A, domain 2 › Threonyl-trna Synthetase; Chain A, domain 2	0.63	53.0	4.65e-01	91.8%	93.8%
2rrnA01	3.30.70.2040	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits ›	0.63	43.0	4.60e-01	83.5%	83.1%
3b8pA00	3.30.1890.10	Alpha Beta › 2-Layer Sandwich › Bacterial polysaccharide co-polymerase-like › FepE-like	0.62	51.0	4.01e-01	90.7%	91.8%
7qh2C03	3.30.70.2740	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits ›	0.62	42.0	4.57e-01	81.4%	87.2%
1vehA01	3.30.300.130	Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › Fe-S cluster assembly (FSCA)	0.61	44.0	4.80e-01	96.9%	98.7%
1z1dB00	3.40.1310.20	Alpha Beta › 3-Layer(aba) Sandwich › Replication Protein E1; Chain: A, ›	0.61	56.0	5.04e-01	100.0%	80.2%
2a6mA00	3.30.70.1290	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Transposase IS200-like	0.61	49.0	4.55e-01	97.9%	67.7%
4y2fA00	3.30.450.40	Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › GAF domain	0.60	44.0	3.88e-01	76.3%	86.0%
6usmB01	3.40.1310.20	Alpha Beta › 3-Layer(aba) Sandwich › Replication Protein E1; Chain: A, ›	0.59	53.0	4.63e-01	99.0%	88.4%
3qtaB00	3.40.1550.10	Alpha Beta › 3-Layer(aba) Sandwich › Chemotaxis protein chec › CheC-like	0.59	50.0	3.94e-01	91.8%	85.4%
7l1iA01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.58	44.0	3.84e-01	81.4%	77.8%
3c6kA01	3.30.160.110	Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Sirohaem synthase, central domain	0.58	45.0	4.64e-01	85.6%	86.2%
1xkoB00	3.40.1550.10	Alpha Beta › 3-Layer(aba) Sandwich › Chemotaxis protein chec › CheC-like	0.57	50.0	4.28e-01	99.0%	94.3%
1q8kA03	3.30.70.1130	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › EIF_2_alpha	0.57	50.0	4.75e-01	100.0%	82.8%
3islA01	3.90.1150.10	Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1	0.57	41.0	3.78e-01	83.5%	57.8%
1jyoA00	3.30.1460.10	Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, ›	0.56	41.0	3.75e-01	83.5%	56.9%
4gs5A02	3.30.300.30	Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › ANL, C-terminal domain	0.56	50.0	4.87e-01	100.0%	93.3%
3znuA00	3.30.70.1060	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Dimeric alpha+beta barrel	0.55	39.0	3.94e-01	90.7%	75.5%
2nrqA00	3.30.1440.10	Alpha Beta › 2-Layer Sandwich › 50s Ribosomal Protein L5; Chain: A, › Ribosomal protein L5	0.55	45.0	4.05e-01	89.7%	80.3%
2w9jA00	3.30.720.10	Alpha Beta › 2-Layer Sandwich › Signal recognition particle alu RNA binding heterodimer, srp9/1 › Signal recognition particle alu RNA binding heterodimer, srp9/1	0.55	28.0	3.15e-01	85.6%	63.4%
6ztgA01	3.30.70.1070	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Sporulation related repeat	0.55	37.0	4.01e-01	90.7%	89.3%
3hm4A00	3.40.1550.10	Alpha Beta › 3-Layer(aba) Sandwich › Chemotaxis protein chec › CheC-like	0.55	46.0	4.09e-01	97.9%	94.8%
3on3B00	3.40.920.10	Alpha Beta › 3-Layer(aba) Sandwich › Pyruvate-ferredoxin Oxidoreductase; domain 3 › Pyruvate-ferredoxin oxidoreductase, PFOR, domain III	0.54	46.0	3.88e-01	95.9%	94.3%
1xttB00	3.40.50.2020	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold ›	0.53	41.0	3.26e-01	83.5%	88.0%
3zmdA00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.53	40.0	3.50e-01	80.4%	83.8%
2g0iA00	3.30.70.1490	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Cysteine protease Prp	0.53	43.0	4.14e-01	89.7%	100.0%
8agaA01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.53	40.0	3.72e-01	80.4%	94.4%
2hj1A00	3.10.20.280	Alpha Beta › Roll › Ubiquitin-like (UB roll) › RnfH-like	0.53	34.0	3.70e-01	97.9%	81.8%
3eayA02	3.30.310.130	Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › Ubiquitin-related	0.52	40.0	3.79e-01	84.5%	71.5%
1vdhA01	3.30.70.1030	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Apc35880; domain 1	0.51	41.0	3.86e-01	90.7%	71.1%
3d3oA00	3.30.450.40	Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › GAF domain	0.51	39.0	3.26e-01	81.4%	98.9%

ECOD (46)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
None	—		0.85	80.0	5.41e-01	100.0%	32.6%
None	—		0.80	74.0	5.10e-01	100.0%	32.3%
4986859	862.1.1.5 ↗	a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain › LigD_Prim-Pol	0.80	74.0	5.12e-01	100.0%	34.2%
1779551	862.1.1.5 ↗	a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain › LigD_Prim-Pol	0.80	73.0	5.09e-01	100.0%	34.2%
2711606	862.1.1.5 ↗	a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain › LigD_Prim-Pol	0.77	71.0	4.79e-01	100.0%	30.6%
3348724	304.4.1.0 ↗	a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel	0.74	56.0	5.49e-01	89.7%	74.3%
4980122	304.39.1.0 ↗	a+b two layers › Alpha-beta plaits › Mechanosensitive channel protein MscS (YggB), C-terminal domain › Mechanosensitive channel protein MscS (YggB), C-terminal domain	0.73	50.0	4.70e-01	71.1%	60.0%
4316518	304.19.1.1 ↗	a+b two layers › Alpha-beta plaits › eIF-2-alpha, C-terminal domain › eIF-2-alpha, C-terminal domain › EIF_2_alpha	0.72	58.0	5.98e-01	94.8%	91.1%
4217176	3016.1.1.0 ↗	a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases	0.71	46.0	4.57e-01	70.1%	63.0%
5072410	306.6.1.6 ↗	a+b two layers › Glucose permease domain IIB-like › PH0987 N-terminal domain-like › PH0987 N-terminal domain-like › GH3_C	0.71	50.0	5.19e-01	73.2%	84.4%
4427482	3016.1.1.0 ↗	a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases	0.71	46.0	4.42e-01	71.1%	58.2%
4978126	304.39.1.0 ↗	a+b two layers › Alpha-beta plaits › Mechanosensitive channel protein MscS (YggB), C-terminal domain › Mechanosensitive channel protein MscS (YggB), C-terminal domain	0.70	48.0	5.31e-01	73.2%	88.5%
4458453	304.28.1.0 ↗	a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain	0.70	54.0	5.79e-01	89.7%	98.8%
3500240	3016.1.1.0 ↗	a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases	0.70	45.0	4.33e-01	70.1%	57.3%
3801312	3016.1.1.0 ↗	a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases	0.70	45.0	4.65e-01	70.1%	70.0%
3617823	3016.1.1.0 ↗	a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases	0.68	44.0	4.56e-01	71.1%	68.8%
5030091	304.19.1.1 ↗	a+b two layers › Alpha-beta plaits › eIF-2-alpha, C-terminal domain › eIF-2-alpha, C-terminal domain › EIF_2_alpha	0.68	50.0	5.32e-01	90.7%	88.2%
3713128	304.120.1.0 ↗	a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in ThiI › Ferredoxin-like domain in ThiI	0.68	44.0	4.93e-01	85.6%	90.0%
5035888	304.19.1.1 ↗	a+b two layers › Alpha-beta plaits › eIF-2-alpha, C-terminal domain › eIF-2-alpha, C-terminal domain › EIF_2_alpha	0.68	51.0	5.46e-01	91.8%	91.8%
3958860	3016.1.1.0 ↗	a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases	0.67	46.0	4.45e-01	70.1%	63.0%
4420323	3016.1.1.0 ↗	a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases	0.66	44.0	4.60e-01	70.1%	74.4%
4331101	304.28.1.2 ↗	a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › Sec_GG	0.66	48.0	5.04e-01	89.7%	87.1%
5048109	304.19.1.1 ↗	a+b two layers › Alpha-beta plaits › eIF-2-alpha, C-terminal domain › eIF-2-alpha, C-terminal domain › EIF_2_alpha	0.66	51.0	5.29e-01	91.8%	90.0%
3280378	304.48.1.0 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like	0.63	54.0	4.57e-01	94.8%	60.6%
3983718	304.48.1.14 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › GGDEF	0.63	54.0	5.16e-01	94.8%	89.6%
4142391	304.48.1.0 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like	0.62	51.0	4.59e-01	93.8%	63.7%
4099808	304.132.1.1 ↗	a+b two layers › Alpha-beta plaits › ferredoxin-like domain in 2,3-bisphosphoglycerate-independent phosphoglycerate mutase › ferredoxin-like domain in 2,3-bisphosphoglycerate-independent phosphoglycerate mutase › PhosphMutase	0.62	54.0	4.71e-01	99.0%	80.0%
4968588	304.55.2.1 ↗	a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Transposase IS200-like › Y1_Tnp	0.62	51.0	4.95e-01	90.7%	80.9%
5042381	2004.1.1.198 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23	0.61	43.0	2.85e-01	72.2%	47.7%
3634662	327.11.2.19 ↗	a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) › KH_11	0.61	42.0	4.35e-01	71.1%	82.2%
3387626	327.11.1.2 ↗	a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Prokaryotic type KH domain (KH-domain type II) › KhpA-B_KH	0.60	46.0	5.00e-01	89.7%	100.0%
3291429	304.48.1.0 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like	0.60	52.0	4.39e-01	94.8%	59.4%
4964645	309.1.1.15 ↗	a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › DEAD_assoc	0.60	54.0	4.43e-01	100.0%	95.6%
4931792	306.3.1.6 ↗	a+b two layers › Glucose permease domain IIB-like › eIF1-like › eIF1-like › DEAD_assoc	0.59	53.0	4.24e-01	100.0%	97.4%
3986253	241.1.1.0 ↗	a+b two layers › Type III secretory system chaperone-like › Type III secretory system chaperone › Type III secretory system chaperone	0.59	40.0	3.80e-01	70.1%	61.7%
5076912	304.4.1.3 ↗	a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › YCII	0.58	40.0	4.34e-01	87.6%	90.7%
3298929	327.6.1.0 ↗	a+b two layers › Alpha-lytic protease prodomain-like › Fe-S cluster assembly (FSCA) domain-like › Fe-S cluster assembly (FSCA) domain-like	0.58	43.0	4.68e-01	89.7%	97.5%
3612606	304.20.1.0 ↗	a+b two layers › Alpha-beta plaits › PAP/Archaeal CCA-adding enzyme, C-terminal domain › PAP/Archaeal CCA-adding enzyme, C-terminal domain	0.58	47.0	4.52e-01	87.6%	89.1%
5051424	304.4.1.3 ↗	a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › YCII	0.57	43.0	4.42e-01	90.7%	84.2%
3171307	306.3.1.1 ↗	a+b two layers › Glucose permease domain IIB-like › eIF1-like › eIF1-like › SUI1	0.56	46.0	4.42e-01	90.7%	81.7%
5072891	241.6.1.0 ↗	a+b two layers › Type III secretory system chaperone-like › Arp2/3 complex subunits › Arp2/3 complex subunits	0.54	37.0	3.21e-01	71.1%	43.6%
4991403	2004.1.1.308 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_21	0.53	42.0	2.94e-01	88.7%	85.8%
5581	306.8.1.1 ↗	a+b two layers › Glucose permease domain IIB-like › TM1457-like › TM1457-like › Peptidase_Prp	0.53	42.0	4.06e-01	87.6%	100.0%
3215880	601.23.1.4 ↗	alpha bundles › Four-helical up-and-down bundle › DNA repair protein MutS, domain III › DNA repair protein MutS, domain III › MutS_IV, MutS_III	0.52	38.0	2.66e-01	82.5%	23.0%
4407831	3281.1.1.2 ↗	alpha complex topology › Sodium/proton antiporter subunits-like › Sodium/proton antiporter subunits-like › NADH-quinone oxidoreductase subunit L (NuoL)-related › Proton_antipo_M,Proton_antipo_N	0.51	43.0	2.68e-01	96.9%	56.5%
4638765	101.1.2.15 ↗	alpha arrays › HTH › HTH › winged helix domain › MarR	0.51	38.0	3.45e-01	81.4%	90.6%