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S16_GE16_scaffold_10741_prodigal-single.1__X__X__00142

Bact-Vir

S16_GE16_scaffold_10741_prodigal-single.1__X__X__00142

Identity

Kingdom:
phage

Quality

92.6 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 2-116_192-233
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02511.21 best Thy1 46.1 6.60e-12 57.3% 41.9%
CATH (18)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2cfaA01 3.30.1360.170 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.83 66.0 6.95e-01 100.0% 90.3%
3ah5B00 3.30.1360.170 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.74 72.0 6.41e-01 100.0% 94.2%
1kq4A00 3.30.1360.170 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.69 67.0 5.99e-01 100.0% 85.7%
4p5aC00 3.30.1360.170 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.69 66.0 5.73e-01 100.0% 88.3%
3mahA01 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.63 29.0 4.10e-01 93.6% 94.3%
3rrkA03 3.30.70.2750 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.61 30.0 4.17e-01 95.5% 98.6%
3im8A02 3.30.70.250 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Malonyl-CoA ACP transacylase, ACP-binding 0.61 29.0 4.05e-01 94.9% 95.9%
3g87A02 3.30.70.250 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Malonyl-CoA ACP transacylase, ACP-binding 0.60 28.0 4.01e-01 95.5% 100.0%
3im9A02 3.30.70.250 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Malonyl-CoA ACP transacylase, ACP-binding 0.58 29.0 4.00e-01 95.5% 100.0%
4bfeA02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.57 30.0 3.97e-01 100.0% 96.3%
2anrA02 3.30.1370.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 0.55 27.0 3.73e-01 88.5% 96.0%
3tqeA02 3.30.70.250 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Malonyl-CoA ACP transacylase, ACP-binding 0.55 28.0 3.78e-01 95.5% 100.0%
2mq8A00 3.30.70.600 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10 0.55 26.0 3.08e-01 79.6% 62.5%
2a2cA02 3.30.70.3170 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.53 29.0 3.79e-01 94.9% 98.8%
2lxfA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.52 29.0 3.21e-01 93.0% 66.1%
1ewqB01 3.40.1170.10 Alpha Beta › 3-Layer(aba) Sandwich › MutS, DNA mismatch repair protein, domain I › DNA repair protein MutS, domain I 0.52 28.0 3.26e-01 100.0% 70.3%
2p92A00 3.30.70.1490 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Cysteine protease Prp 0.52 32.0 3.91e-01 100.0% 98.9%
2joeA01 3.30.1830.10 Alpha Beta › 2-Layer Sandwich › YehR-like fold › YehR-like 0.52 33.0 3.63e-01 100.0% 78.1%
ECOD (54)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5024486 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.91 72.0 6.23e-01 80.9% 86.2%
5077404 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.82 79.0 6.62e-01 100.0% 82.4%
5069296 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.80 78.0 6.37e-01 100.0% 72.5%
4246528 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.79 77.0 6.41e-01 100.0% 84.0%
4133204 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.79 76.0 6.43e-01 100.0% 80.8%
4977743 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.79 76.0 7.14e-01 100.0% 89.2%
4102574 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.79 76.0 6.40e-01 100.0% 93.3%
4930760 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.79 76.0 6.22e-01 100.0% 73.5%
4152367 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.79 76.0 5.84e-01 100.0% 78.4%
5046119 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.79 76.0 6.76e-01 100.0% 91.8%
4933142 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.79 75.0 6.44e-01 100.0% 91.7%
4943595 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.78 75.0 6.49e-01 100.0% 83.6%
5001652 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.77 74.0 6.04e-01 100.0% 73.1%
134624 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.76 74.0 6.14e-01 100.0% 87.0%
4134497 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.76 73.0 6.26e-01 100.0% 78.3%
4300356 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.76 73.0 6.64e-01 100.0% 95.5%
143031 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.75 72.0 6.42e-01 100.0% 93.8%
1007250 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.72 68.0 6.21e-01 100.0% 94.0%
4992830 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.70 68.0 5.86e-01 100.0% 81.3%
4988219 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.70 66.0 5.50e-01 98.7% 90.4%
4264204 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.69 67.0 5.36e-01 100.0% 86.2%
4292511 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.69 67.0 4.50e-01 100.0% 48.9%
4942790 304.126.1.0 a+b two layers › Alpha-beta plaits › ferredoxin-like domain in vacuolar ATP synthase subunit C › ferredoxin-like domain in vacuolar ATP synthase subunit C 0.66 30.0 4.12e-01 95.5% 83.7%
4985048 304.126.1.0 a+b two layers › Alpha-beta plaits › ferredoxin-like domain in vacuolar ATP synthase subunit C › ferredoxin-like domain in vacuolar ATP synthase subunit C 0.66 29.0 4.02e-01 93.0% 81.2%
4080136 304.126.1.0 a+b two layers › Alpha-beta plaits › ferredoxin-like domain in vacuolar ATP synthase subunit C › ferredoxin-like domain in vacuolar ATP synthase subunit C 0.66 32.0 4.44e-01 95.5% 96.0%
5006971 304.126.1.0 a+b two layers › Alpha-beta plaits › ferredoxin-like domain in vacuolar ATP synthase subunit C › ferredoxin-like domain in vacuolar ATP synthase subunit C 0.64 29.0 3.98e-01 95.5% 83.7%
3915495 304.11.1.0 a+b two layers › Alpha-beta plaits › Probable ACP-binding domain of malonyl-CoA ACP transacylase › Probable ACP-binding domain of malonyl-CoA ACP transacylase 0.63 30.0 4.32e-01 95.5% 100.0%
4263279 304.11.1.0 a+b two layers › Alpha-beta plaits › Probable ACP-binding domain of malonyl-CoA ACP transacylase › Probable ACP-binding domain of malonyl-CoA ACP transacylase 0.63 31.0 4.04e-01 94.9% 84.7%
5010365 304.126.1.0 a+b two layers › Alpha-beta plaits › ferredoxin-like domain in vacuolar ATP synthase subunit C › ferredoxin-like domain in vacuolar ATP synthase subunit C 0.63 29.0 4.15e-01 97.5% 97.1%
4207617 304.11.1.0 a+b two layers › Alpha-beta plaits › Probable ACP-binding domain of malonyl-CoA ACP transacylase › Probable ACP-binding domain of malonyl-CoA ACP transacylase 0.63 29.0 4.10e-01 93.6% 95.7%
4490518 304.11.1.0 a+b two layers › Alpha-beta plaits › Probable ACP-binding domain of malonyl-CoA ACP transacylase › Probable ACP-binding domain of malonyl-CoA ACP transacylase 0.62 30.0 4.19e-01 77.7% 98.6%
4220147 304.126.1.0 a+b two layers › Alpha-beta plaits › ferredoxin-like domain in vacuolar ATP synthase subunit C › ferredoxin-like domain in vacuolar ATP synthase subunit C 0.61 32.0 4.24e-01 97.5% 92.9%
4012870 304.11.1.0 a+b two layers › Alpha-beta plaits › Probable ACP-binding domain of malonyl-CoA ACP transacylase › Probable ACP-binding domain of malonyl-CoA ACP transacylase 0.61 30.0 4.16e-01 94.9% 100.0%
5043867 304.126.1.0 a+b two layers › Alpha-beta plaits › ferredoxin-like domain in vacuolar ATP synthase subunit C › ferredoxin-like domain in vacuolar ATP synthase subunit C 0.61 29.0 4.04e-01 95.5% 93.3%
5056226 304.126.1.0 a+b two layers › Alpha-beta plaits › ferredoxin-like domain in vacuolar ATP synthase subunit C › ferredoxin-like domain in vacuolar ATP synthase subunit C 0.61 29.0 4.04e-01 77.7% 98.6%
3961146 304.11.1.1 a+b two layers › Alpha-beta plaits › Probable ACP-binding domain of malonyl-CoA ACP transacylase › Probable ACP-binding domain of malonyl-CoA ACP transacylase › Acyl_transf_1 0.60 31.0 3.36e-01 96.8% 57.4%
4112187 304.126.1.0 a+b two layers › Alpha-beta plaits › ferredoxin-like domain in vacuolar ATP synthase subunit C › ferredoxin-like domain in vacuolar ATP synthase subunit C 0.60 28.0 3.93e-01 93.6% 95.7%
4935067 304.126.1.0 a+b two layers › Alpha-beta plaits › ferredoxin-like domain in vacuolar ATP synthase subunit C › ferredoxin-like domain in vacuolar ATP synthase subunit C 0.60 32.0 4.22e-01 98.7% 95.3%
4448591 304.11.1.0 a+b two layers › Alpha-beta plaits › Probable ACP-binding domain of malonyl-CoA ACP transacylase › Probable ACP-binding domain of malonyl-CoA ACP transacylase 0.59 28.0 3.91e-01 95.5% 95.7%
4679554 304.11.1.1 a+b two layers › Alpha-beta plaits › Probable ACP-binding domain of malonyl-CoA ACP transacylase › Probable ACP-binding domain of malonyl-CoA ACP transacylase › Acyl_transf_1 0.59 30.0 4.05e-01 94.9% 95.0%
3960306 304.11.1.0 a+b two layers › Alpha-beta plaits › Probable ACP-binding domain of malonyl-CoA ACP transacylase › Probable ACP-binding domain of malonyl-CoA ACP transacylase 0.59 29.0 3.96e-01 95.5% 96.0%
135123 304.11.1.0 a+b two layers › Alpha-beta plaits › Probable ACP-binding domain of malonyl-CoA ACP transacylase › Probable ACP-binding domain of malonyl-CoA ACP transacylase 0.58 28.0 3.94e-01 79.6% 100.0%
4580140 242.1.1.0 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.58 24.0 3.10e-01 99.4% 65.9%
4106532 304.117.1.1 a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in YebC › Ferredoxin-like domain in YebC › Transcrip_reg 0.57 28.0 3.72e-01 94.3% 92.0%
4970273 304.126.1.0 a+b two layers › Alpha-beta plaits › ferredoxin-like domain in vacuolar ATP synthase subunit C › ferredoxin-like domain in vacuolar ATP synthase subunit C 0.57 32.0 4.17e-01 96.8% 96.7%
3251998 242.1.1.1 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_1 0.57 30.0 3.57e-01 100.0% 73.3%
4025260 304.110.1.0 a+b two layers › Alpha-beta plaits › Acylphosphatase-like › Acylphosphatase-like 0.57 36.0 4.00e-01 94.3% 80.8%
4151231 304.117.1.1 a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in YebC › Ferredoxin-like domain in YebC › Transcrip_reg 0.56 28.0 3.69e-01 96.2% 93.3%
3257902 304.11.1.0 a+b two layers › Alpha-beta plaits › Probable ACP-binding domain of malonyl-CoA ACP transacylase › Probable ACP-binding domain of malonyl-CoA ACP transacylase 0.55 32.0 4.04e-01 94.9% 97.8%
3266841 304.8.1.22 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › AHAS-like_ACT 0.55 31.0 4.00e-01 80.9% 100.0%
3784887 304.9.1.1 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.53 27.0 3.64e-01 94.9% 100.0%
3847407 327.11.2.23 a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) › KH_PARP14_8 0.52 26.0 3.35e-01 89.8% 83.5%
3720272 304.9.1.0 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.51 33.0 3.95e-01 72.6% 100.0%
4000154 242.3.1.1 a+b two layers › Homing endonucleases-like › DNA repair protein MutS, domain I › DNA repair protein MutS, domain I › MutS_I 0.51 32.0 3.60e-01 95.5% 81.7%
D2 high residues 128-187
PDB
CATH (45)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1s7zA01 1.20.120.780 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › DNA mimic ocr 0.81 55.0 4.51e-01 70.0% 41.6%
1sg7A00 1.10.1740.70 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › ChaB 0.80 55.0 5.09e-01 75.0% 57.3%
3l1nA02 1.20.1280.140 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.77 59.0 5.19e-01 96.7% 56.3%
3ermB00 1.10.10.710 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › PSPTO_1197 like 0.77 54.0 5.36e-01 80.0% 70.3%
2wdqC00 1.20.1300.10 Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit 0.75 60.0 4.80e-01 90.0% 45.5%
4dciA00 6.10.140.1110 Special › Helix non-globular › Helix Hairpins › 0.73 62.0 4.65e-01 93.3% 42.9%
3gi7A00 1.20.1270.180 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.72 64.0 5.32e-01 98.3% 90.3%
2e62A01 6.10.140.420 Special › Helix non-globular › Helix Hairpins › 0.72 53.0 5.58e-01 81.7% 94.2%
4gx0A01 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.72 60.0 4.93e-01 90.0% 72.8%
4id0A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.71 54.0 4.33e-01 81.7% 42.9%
3cxbA03 1.10.1740.30 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › Secreted effector protein SifA helical domain 0.71 54.0 4.95e-01 85.0% 64.2%
1l1lA01 3.20.70.20 Alpha Beta › Alpha-Beta Barrel › Anaerobic Ribonucleotide-triphosphate Reductase Large Chain › 0.70 54.0 3.13e-01 83.3% 12.3%
3x0uB01 1.20.190.10 Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain 0.70 60.0 3.99e-01 96.7% 28.4%
1rh5A00 1.10.3370.10 Mainly Alpha › Orthogonal Bundle › Preprotein translocase SecY subunit › SecY subunit domain 0.69 58.0 3.51e-01 96.7% 16.8%
5l3wA01 1.20.120.140 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SRP54, nucleotide-binding domain 0.68 47.0 4.27e-01 73.3% 52.4%
4lp8A01 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.67 52.0 4.37e-01 85.0% 80.8%
1qsdA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.67 53.0 4.47e-01 90.0% 51.0%
2khmA01 1.10.10.1350 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Spidroin domain, C-terminal domain 0.65 46.0 3.80e-01 73.3% 42.6%
2qksA01 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.65 51.0 4.23e-01 85.0% 79.2%
3vm9A02 6.10.140.2110 Special › Helix non-globular › Helix Hairpins › 0.65 46.0 4.73e-01 76.7% 80.7%
1rp3A01 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.65 48.0 4.31e-01 81.7% 56.5%
2efkA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.65 51.0 3.36e-01 91.7% 19.8%
3iieB03 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.64 45.0 4.08e-01 80.0% 52.9%
6yz2A01 1.20.120.350 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C 0.64 52.0 4.22e-01 91.7% 57.5%
8ctsB01 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.64 44.0 3.92e-01 73.3% 79.3%
2y39A00 1.20.120.1490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.63 51.0 4.26e-01 93.3% 51.8%
2lm9A00 1.20.58.970 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.63 54.0 4.62e-01 96.7% 62.5%
4e6nA02 6.10.140.1010 Special › Helix non-globular › Helix Hairpins › 0.63 52.0 5.03e-01 100.0% 81.8%
3mq1A01 1.20.58.970 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.62 53.0 4.64e-01 100.0% 62.0%
4ikhA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.62 45.0 3.64e-01 80.0% 39.4%
3ousA00 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.62 46.0 4.23e-01 81.7% 87.8%
4l8jA04 1.10.287.470 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.61 46.0 4.65e-01 81.7% 83.1%
3fppA03 6.10.140.1990 Special › Helix non-globular › Helix Hairpins › 0.61 49.0 4.40e-01 91.7% 62.5%
2ktmA00 1.10.790.10 Mainly Alpha › Orthogonal Bundle › Major Prion Protein › Prion/Doppel protein, beta-ribbon domain 0.61 45.0 4.36e-01 81.7% 76.5%
1vf7A03 1.10.287.470 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.60 45.0 4.50e-01 80.0% 80.0%
3u9rB02 3.90.226.10 Alpha Beta › Alpha-Beta Complex › 2-enoyl-CoA Hydratase; Chain A, domain 1 › 2-enoyl-CoA Hydratase; Chain A, domain 1 0.60 48.0 3.24e-01 95.0% 68.4%
4aflA00 6.10.140.1740 Special › Helix non-globular › Helix Hairpins › 0.60 49.0 4.22e-01 95.0% 66.7%
1a3qA01 2.60.40.340 Mainly Beta › Sandwich › Immunoglobulin-like › Rel homology domain (RHD), DNA-binding domain 0.58 40.0 2.97e-01 73.3% 25.1%
1e91A00 1.20.1160.11 Mainly Alpha › Up-down Bundle › Paired amphipathic helix 2 (pah2 repeat) › Paired amphipathic helix 0.58 40.0 3.57e-01 100.0% 50.6%
4cc9B00 1.20.5.4730 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.58 40.0 3.47e-01 73.3% 45.9%
1br0A00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.57 47.0 3.86e-01 96.7% 59.2%
4mtxD00 1.10.287.130 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain 0.55 45.0 3.98e-01 96.7% 60.0%
3wfwA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.55 42.0 3.42e-01 91.7% 70.3%
4olsA00 3.40.80.10 Alpha Beta › 3-Layer(aba) Sandwich › Lysozyme-like › Peptidoglycan recognition protein-like 0.53 43.0 2.95e-01 85.0% 42.7%
1dt9A01 3.30.960.10 Alpha Beta › 2-Layer Sandwich › Translation, Eukaryotic Peptide Chain Release Factor Subunit 1; Chain A › eRF1 domain 1 0.52 38.0 3.22e-01 80.0% 81.0%
ECOD (43)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4232288 4275.1.1.10 alpha arrays › Hypothetical protein YqbG-like › Hypothetical protein YqbG-like › Hypothetical protein YqbG-like › NifW 0.85 61.0 5.79e-01 76.7% 64.3%
3597447 5076.1.1.0 alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier 0.81 74.0 4.66e-01 100.0% 30.2%
4514462 547.1.1.1 alpha duplicates or obligate multimers › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › GlutR_dimer 0.80 71.0 5.95e-01 98.3% 61.0%
3341345 6026.1.1.0 alpha duplicates or obligate multimers › cwf21 domain › cwf21 domain › cwf21 domain 0.80 66.0 5.07e-01 90.0% 43.1%
3940867 632.22.1.67 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › DUF842 0.79 70.0 6.03e-01 100.0% 69.5%
3576309 103.4.1.0 alpha arrays › RuvA-C › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein 0.78 65.0 5.43e-01 90.0% 72.0%
3296105 5076.1.1.1 alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier › Mito_carr 0.76 69.0 4.32e-01 100.0% 30.3%
4955443 3542.1.1.0 alpha arrays › Presenilin family intramembrane aspartate proteases › Presenilin family intramembrane aspartate proteases › Presenilin family intramembrane aspartate proteases 0.75 60.0 3.85e-01 85.0% 45.2%
5039640 1075.1.2.13 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › CNNM 0.75 65.0 4.65e-01 96.7% 52.9%
3518379 3502.1.1.1 alpha bundles › uncharacterized conserved protein › uncharacterized conserved protein › uncharacterized conserved protein › YebG 0.75 53.0 5.53e-01 80.0% 81.8%
3588971 6026.1.1.0 alpha duplicates or obligate multimers › cwf21 domain › cwf21 domain › cwf21 domain 0.75 59.0 5.49e-01 86.7% 69.3%
None 0.74 66.0 4.19e-01 100.0% 39.0%
4964045 5058.1.1.16 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 0.74 61.0 5.51e-01 93.3% 70.6%
3207650 5076.1.1.1 alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier › Mito_carr 0.73 64.0 4.08e-01 100.0% 29.7%
3481083 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.73 61.0 4.00e-01 93.3% 25.2%
3493291 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.73 60.0 4.32e-01 91.7% 67.6%
4011947 5076.1.1.0 alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier 0.72 63.0 4.03e-01 100.0% 35.6%
3958634 5067.1.1.4 alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › MMPL 0.72 64.0 4.42e-01 100.0% 57.0%
3389798 2006.1.4.0 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like 0.71 50.0 4.81e-01 75.0% 65.7%
3852378 4177.1.1.61 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › PLC-beta_C 0.71 59.0 3.90e-01 93.3% 22.3%
4022959 5076.1.1.0 alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier 0.70 62.0 4.03e-01 100.0% 35.6%
3853882 192.15.1.0 alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains 0.70 62.0 4.75e-01 98.3% 57.0%
3899594 5076.1.1.1 alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier › Mito_carr 0.70 62.0 4.01e-01 100.0% 29.8%
3863863 5076.1.1.1 alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier › Mito_carr 0.70 61.0 3.90e-01 100.0% 31.0%
3626061 6026.1.1.17 alpha duplicates or obligate multimers › cwf21 domain › cwf21 domain › cwf21 domain › ApoO 0.70 49.0 4.06e-01 83.3% 40.9%
3960409 191.1.1.0 alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain 0.69 55.0 4.47e-01 88.3% 47.8%
5028719 5076.2.1.0 alpha complex topology › Mitochondrial ADP/ATP carrier-like › Putative sulfate permease CysZ › Putative sulfate permease CysZ 0.68 57.0 3.80e-01 95.0% 24.7%
5078048 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.68 57.0 5.26e-01 88.3% 76.0%
4547274 3714.1.1.0 a+b two layers › Lon-like protease MtaLonC helical domain › Lon-like protease MtaLonC helical domain › Lon-like protease MtaLonC helical domain 0.68 59.0 5.01e-01 98.3% 81.0%
4275437 5063.1.1.12 alpha bundles › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK › ApoO 0.67 48.0 4.85e-01 76.7% 81.7%
5063791 1075.3.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC importer transmembrane domain fold › Type I ABC importer transmembrane domain fold › BPD_transp_1 0.67 56.0 3.59e-01 100.0% 79.1%
2622460 3396.1.1.1 extended segments › HIG1 domain family member 1A › HIG1 domain family member 1A › HIG1 domain family member 1A › HIG_1_N 0.67 52.0 5.02e-01 88.3% 74.3%
3981640 5058.1.1.2 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st 0.66 54.0 4.73e-01 90.0% 60.0%
3258488 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.65 48.0 4.11e-01 80.0% 48.0%
5051613 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.65 47.0 3.83e-01 80.0% 39.8%
4962781 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.64 50.0 4.63e-01 85.0% 66.7%
3387239 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.63 51.0 4.08e-01 91.7% 45.0%
4540106 3396.1.1.3 extended segments › HIG1 domain family member 1A › HIG1 domain family member 1A › HIG1 domain family member 1A › DUF4481 0.62 47.0 4.42e-01 88.3% 67.5%
4163021 5054.1.1.8 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 0.62 56.0 4.70e-01 100.0% 76.0%
3495550 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.62 52.0 4.40e-01 100.0% 55.2%
3734442 192.8.1.35 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › DUF6594 0.59 53.0 4.07e-01 100.0% 45.4%
3593206 142.1.1.0 alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors 0.59 50.0 4.31e-01 95.0% 61.1%
4793214 5054.1.1.8 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 0.55 44.0 3.72e-01 90.0% 67.3%
D3 high residues 275-282_334-377_418-484
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02511.21 best Thy1 52.6 6.60e-14 44.5% 25.7%
CATH (28)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1kq4A00 3.30.1360.170 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.89 83.0 6.66e-01 95.8% 94.6%
3ah5B00 3.30.1360.170 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.88 79.0 6.34e-01 92.4% 99.0%
4p5aC00 3.30.1360.170 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.86 81.0 6.33e-01 97.5% 93.3%
2af6A01 3.30.70.3180 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.82 77.0 7.40e-01 96.6% 94.7%
2cfaA01 3.30.1360.170 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.78 73.0 6.81e-01 98.3% 97.9%
2mdaA00 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.60 42.0 4.65e-01 75.6% 91.6%
4iyqA00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.59 41.0 4.36e-01 73.1% 85.0%
4e98C00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.58 41.0 4.38e-01 76.5% 82.9%
3aawA02 3.30.2130.10 Alpha Beta › 2-Layer Sandwich › VC0802-like › VC0802-like 0.58 40.0 3.67e-01 79.0% 51.5%
3lnlB02 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.58 39.0 4.35e-01 76.5% 92.0%
3n5fA02 3.30.70.360 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.58 41.0 4.19e-01 73.1% 100.0%
4pxdA02 3.30.70.360 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.57 40.0 4.13e-01 73.1% 100.0%
3trgA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.56 37.0 4.04e-01 71.4% 84.0%
3bb5A00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.55 38.0 4.06e-01 70.6% 99.0%
1wi8A01 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.54 35.0 4.09e-01 73.9% 100.0%
2cc6A00 3.30.1660.10 Alpha Beta › 2-Layer Sandwich › Dodecin subunit-like › Flavin-binding protein dodecin 0.53 29.0 3.79e-01 76.5% 100.0%
4e6nB00 3.30.1610.20 Alpha Beta › 2-Layer Sandwich › c-terminal autoproteolytic domain of nucleoporin nup98 › Hen1, N-terminal domain 0.53 46.0 3.76e-01 95.8% 98.6%
5eufA01 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.51 43.0 3.56e-01 93.3% 89.2%
5xzqF00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.51 37.0 3.97e-01 76.5% 97.1%
4nnzA01 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.51 42.0 3.63e-01 92.4% 89.5%
1bccA01 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.51 42.0 3.53e-01 91.6% 91.6%
1zbtA02 3.30.70.1660 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.51 42.0 3.82e-01 90.8% 100.0%
2fgeA04 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.51 40.0 3.25e-01 87.4% 89.6%
1tr0A00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.51 36.0 3.76e-01 73.1% 97.2%
2vfrA04 3.30.70.2520 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.51 36.0 3.92e-01 73.9% 100.0%
1q2lA01 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.51 41.0 3.34e-01 90.8% 81.9%
2vzyC00 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.51 36.0 3.18e-01 74.8% 89.4%
1nxiA00 3.30.70.970 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RraB-like 0.50 37.0 3.60e-01 77.3% 74.2%
ECOD (57)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5029299 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.95 86.0 6.82e-01 92.4% 96.7%
4943595 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.94 87.0 6.74e-01 95.0% 91.1%
4345249 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.94 84.0 6.55e-01 92.4% 90.2%
4292511 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.94 84.0 5.34e-01 92.4% 37.7%
5024487 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.94 84.0 6.70e-01 92.4% 98.1%
4926808 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.93 84.0 6.60e-01 93.3% 93.6%
5054516 842.1.1.0 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 0.92 77.0 6.45e-01 86.6% 100.0%
4152367 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.92 88.0 6.24e-01 100.0% 89.4%
4992830 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.91 83.0 6.52e-01 95.0% 94.2%
4941740 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.90 85.0 5.39e-01 97.5% 44.1%
5077404 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.90 86.0 6.55e-01 99.2% 98.4%
4246528 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.90 86.0 6.56e-01 99.2% 98.4%
4300356 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.90 78.0 6.33e-01 89.1% 99.0%
4977743 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.90 81.0 6.74e-01 92.4% 95.1%
5001652 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.90 85.0 6.35e-01 98.3% 88.8%
4930760 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.90 85.0 6.35e-01 98.3% 86.5%
4133204 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.90 85.0 6.48e-01 98.3% 97.5%
5066566 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.90 82.0 6.50e-01 95.8% 94.5%
4134497 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.90 83.0 6.41e-01 95.8% 91.3%
4628182 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.90 81.0 6.09e-01 94.1% 84.7%
134624 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.90 83.0 6.32e-01 96.6% 96.7%
4982008 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.89 83.0 6.72e-01 95.8% 96.0%
4933143 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.89 83.0 6.72e-01 96.6% 92.6%
143031 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.89 80.0 6.40e-01 93.3% 99.0%
4988219 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.88 80.0 6.09e-01 95.0% 96.8%
4102574 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.88 83.0 6.29e-01 97.5% 98.3%
5069296 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.87 76.0 5.71e-01 90.8% 77.3%
5046119 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.87 80.0 6.44e-01 95.8% 97.6%
1716752 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.85 81.0 6.31e-01 98.3% 93.8%
4060791 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.85 81.0 6.10e-01 100.0% 94.9%
4264204 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.84 77.0 5.69e-01 96.6% 92.0%
1007250 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.82 77.0 6.30e-01 98.3% 99.5%
5054515 842.1.1.0 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 0.80 73.0 5.90e-01 96.6% 93.8%
4955043 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.79 73.0 6.67e-01 95.8% 96.7%
5018373 842.1.1.0 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 0.77 71.0 5.74e-01 97.5% 98.6%
4120000 304.24.1.1 a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like › EFG_C 0.61 44.0 4.39e-01 74.8% 93.6%
5079732 304.4.1.0 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.60 41.0 4.65e-01 76.5% 93.3%
3227524 304.9.1.0 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.60 51.0 5.11e-01 92.4% 90.8%
4326469 304.44.1.2 a+b two layers › Alpha-beta plaits › Ribosomal protein S10 › Ribosomal protein S10 › PriA_C 0.59 40.0 4.53e-01 75.6% 96.5%
3784654 304.8.1.1 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › Thr_dehydrat_C 0.58 37.0 4.07e-01 74.8% 80.9%
5050897 304.130.1.1 a+b two layers › Alpha-beta plaits › Uncharacterized protein MK0293 N-terminal domain › Uncharacterized protein MK0293 N-terminal domain › Ni_insertion 0.56 37.0 4.23e-01 76.5% 94.1%
3823137 304.126.1.1 a+b two layers › Alpha-beta plaits › ferredoxin-like domain in vacuolar ATP synthase subunit C › ferredoxin-like domain in vacuolar ATP synthase subunit C › V_ATPase_I 0.56 42.0 4.01e-01 78.2% 93.6%
5030215 242.1.1.7 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3 0.56 37.0 3.88e-01 83.2% 73.6%
3501565 304.114.1.0 a+b two layers › Alpha-beta plaits › Family B DNA polymerase insertion domain › Family B DNA polymerase insertion domain 0.54 40.0 3.76e-01 77.3% 71.0%
3555669 304.126.1.1 a+b two layers › Alpha-beta plaits › ferredoxin-like domain in vacuolar ATP synthase subunit C › ferredoxin-like domain in vacuolar ATP synthase subunit C › V_ATPase_I 0.54 41.0 4.10e-01 79.0% 95.0%
5060 304.9.1.1 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.54 37.0 3.87e-01 77.3% 79.8%
3559194 5067.1.1.25 alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › PF27572 0.54 47.0 2.93e-01 100.0% 84.0%
3637901 304.9.1.0 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.53 40.0 4.23e-01 80.7% 99.0%
5057185 882.1.1.4 a+b two layers › Ribosomal protein L5 › Ribosomal protein L5 › Ribosomal protein L5 › RNA_binding 0.53 42.0 4.03e-01 87.4% 100.0%
4515208 304.24.1.7 a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like › V_ATPase_I 0.53 40.0 4.07e-01 79.0% 96.5%
4308216 304.8.1.5 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › NIL 0.53 38.0 4.14e-01 81.5% 94.7%
3575538 304.126.1.1 a+b two layers › Alpha-beta plaits › ferredoxin-like domain in vacuolar ATP synthase subunit C › ferredoxin-like domain in vacuolar ATP synthase subunit C › V_ATPase_I 0.53 39.0 4.11e-01 79.0% 88.2%
3740046 304.9.1.1 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.53 38.0 3.77e-01 75.6% 69.2%
4572272 242.1.1.0 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.52 39.0 3.94e-01 99.2% 80.0%
5505 309.1.1.7 a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › M16C_assoc 0.51 40.0 3.22e-01 87.4% 86.8%
2390627 304.4.1.5 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › Dyp_perox_N 0.51 36.0 3.45e-01 72.3% 86.8%
4230274 11.2.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain 0.51 40.0 3.53e-01 87.4% 97.4%
D4 medium residues 283-333
PDB
Domain cluster: representative
CATH (20)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1wj7A01 1.10.8.10 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain 0.78 51.0 4.80e-01 72.5% 56.7%
2f8lA01 1.10.150.470 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 0.78 60.0 5.08e-01 82.4% 55.6%
2l4eA00 1.10.8.10 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain 0.76 50.0 4.80e-01 72.5% 59.6%
8ctsB01 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.74 53.0 4.43e-01 76.5% 60.9%
1s8nA02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.72 53.0 5.13e-01 80.4% 84.5%
3ousA00 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.71 51.0 4.38e-01 76.5% 65.9%
4cs9B02 1.20.120.1350 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Pneumovirus matrix protein 2 (M2), zinc-binding domain 0.71 61.0 4.83e-01 98.0% 97.2%
1qo0D02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.70 49.0 5.09e-01 74.5% 97.8%
6wshA02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.69 51.0 5.07e-01 80.4% 81.8%
3vz3A01 3.40.605.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 0.67 51.0 3.25e-01 82.4% 43.0%
3rosA01 3.40.605.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 0.65 50.0 3.22e-01 86.3% 46.3%
1zkdA03 6.10.250.3300 Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.61 37.0 3.98e-01 80.4% 69.8%
4eeiA03 1.10.40.30 Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase Protein R1; domain 1 › Fumarase/aspartase (C-terminal domain) 0.61 51.0 4.51e-01 98.0% 83.3%
1nmrA01 1.10.1900.10 Mainly Alpha › Orthogonal Bundle › c-terminal domain of poly(a) binding protein › c-terminal domain of poly(a) binding protein 0.58 42.0 3.79e-01 80.4% 53.9%
1owfA00 4.10.520.10 Few Secondary Structures › Irregular › HU Protein; Chain A › IHF-like DNA-binding proteins 0.58 47.0 3.86e-01 90.2% 96.9%
4d7rA01 1.10.220.20 Mainly Alpha › Orthogonal Bundle › Annexin V; domain 1 › 0.58 37.0 3.15e-01 82.4% 39.0%
3otdA00 3.30.70.3000 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › tRNA(His) guanylyltransferase (Thg1) 0.57 46.0 3.10e-01 98.0% 22.5%
2l0rA00 3.40.390.10 Alpha Beta › 3-Layer(aba) Sandwich › Collagenase (Catalytic Domain) › Collagenase (Catalytic Domain) 0.55 43.0 3.46e-01 88.2% 85.8%
1rp5A03 3.30.70.2110 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.55 44.0 3.78e-01 96.1% 91.1%
4jz8B00 3.40.1160.10 Alpha Beta › 3-Layer(aba) Sandwich › Carbamate kinase › Acetylglutamate kinase-like 0.50 43.0 2.67e-01 100.0% 72.0%
ECOD (18)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4345249 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.88 79.0 5.07e-01 100.0% 23.1%
4926808 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.85 76.0 4.91e-01 100.0% 25.9%
3537150 103.1.1.2 alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain › CUE 0.75 49.0 4.78e-01 72.5% 61.8%
4142281 105.1.1.55 alpha duplicates or obligate multimers › HLH-like › HLH, helix-loop-helix DNA-binding domain › HLH, helix-loop-helix DNA-binding domain › Latarcin 0.75 61.0 5.02e-01 92.2% 53.2%
3598252 190.1.1.0 alpha arrays › HMG-box-like › HMG-box › HMG-box 0.74 58.0 5.84e-01 84.3% 98.0%
4980843 242.4.1.0 a+b two layers › Homing endonucleases-like › DNA polymerase II large subunit DP2 central a+b domain › DNA polymerase II large subunit DP2 central a+b domain 0.73 57.0 4.06e-01 84.3% 95.9%
3960463 103.12.1.0 alpha arrays › RuvA-C › ANTAR domain › ANTAR domain 0.71 52.0 5.01e-01 80.4% 80.0%
4185405 589.1.2.1 alpha arrays › Triger factor/SurA peptide-binding domain-like › Triger factor/SurA peptide-binding domain-like › TF C-terminus (Pfam 05698) › Trigger_C 0.71 58.0 4.09e-01 94.1% 30.9%
3608559 3721.1.1.1 alpha bundles › Protein regulator of cytokinesis 1 (PRC1) dimerization domain › Protein regulator of cytokinesis 1 (PRC1) dimerization domain › Protein regulator of cytokinesis 1 (PRC1) dimerization domain › VIT1 0.71 54.0 4.93e-01 86.3% 65.7%
3959245 103.12.1.1 alpha arrays › RuvA-C › ANTAR domain › ANTAR domain › ANTAR 0.70 55.0 4.64e-01 86.3% 60.0%
3289310 103.12.1.1 alpha arrays › RuvA-C › ANTAR domain › ANTAR domain › ANTAR 0.70 55.0 5.41e-01 88.2% 96.4%
4159891 7556.1.1.1 a/b three-layered sandwiches › Fe-only hydrogenase › Fe-only hydrogenase › Fe-only hydrogenase › Fe_hyd_lg_C 0.66 55.0 3.37e-01 100.0% 55.3%
5074147 304.48.1.20 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Thg1 0.66 51.0 3.39e-01 90.2% 55.2%
1159512 4953.1.1.0 beta barrels › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like 0.61 51.0 4.25e-01 98.0% 69.1%
3186355 304.48.1.21 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Thg1,Thg1C 0.59 45.0 2.92e-01 88.2% 17.3%
2138980 235.1.1.19 a+b complex topology › Lysozyme-like › Lysozyme-like › Lysozyme-like › SLT_2 0.59 45.0 2.85e-01 86.3% 42.1%
4074758 5065.1.1.1 alpha bundles › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › ABC-3 0.54 41.0 2.70e-01 88.2% 24.7%
3483657 176.1.1.0 alpha arrays › Annexin › Annexin › Annexin 0.52 36.0 3.57e-01 82.4% 70.9%