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S27_BME27_629333_prodigal-single.1__X__X__00161
Bact-VirS27_BME27_629333_prodigal-single.1__X__X__00161
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 10-95
Domain cluster:
rep: hypothetical_protein_pv_453__YP_009001354__Pithovirus_sibericum__1450746__D11-100
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF03013.20 best | Pyr_excise | 31.2 | 3.10e-07 | 81.4% | 77.8% |
CATH (39)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1j5wA02 | 1.20.58.180 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Class II aaRS and biotin synthetases; domain 2 | 0.73 | 57.0 | 6.06e-01 | 83.7% | 92.2% |
| 3n2oA03 | 1.20.58.930 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.69 | 55.0 | 5.29e-01 | 83.7% | 82.3% |
| 2lm9A00 | 1.20.58.970 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.68 | 51.0 | 4.97e-01 | 80.2% | 94.8% |
| 1yxrA01 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.67 | 51.0 | 5.46e-01 | 80.2% | 95.9% |
| 2gscC00 | 1.20.1440.60 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence | 0.67 | 53.0 | 4.85e-01 | 83.7% | 71.8% |
| 2qsbA00 | 1.20.1440.50 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Ta0600-like | 0.66 | 45.0 | 4.58e-01 | 79.1% | 71.8% |
| 4ezbA02 | 1.10.1040.10 | Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 | 0.66 | 49.0 | 4.44e-01 | 79.1% | 82.1% |
| 2clbA01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.65 | 50.0 | 4.17e-01 | 83.7% | 89.9% |
| 3uumA00 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.64 | 50.0 | 4.48e-01 | 83.7% | 82.8% |
| 2d9dA00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.64 | 51.0 | 5.11e-01 | 84.9% | 88.8% |
| 1vcsA00 | 1.20.58.400 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins | 0.62 | 48.0 | 4.60e-01 | 83.7% | 87.3% |
| 1u5pA01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.62 | 47.0 | 4.38e-01 | 81.4% | 87.0% |
| 5m9dA00 | 1.25.40.90 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.62 | 52.0 | 4.49e-01 | 94.2% | 60.9% |
| 6d5xA00 | 1.20.1200.10 | Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like | 0.62 | 48.0 | 3.99e-01 | 83.7% | 88.7% |
| 3lbxB01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.60 | 46.0 | 4.27e-01 | 81.4% | 88.8% |
| 3nbxX03 | 1.20.58.1510 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.60 | 45.0 | 4.32e-01 | 80.2% | 84.2% |
| 4wqoD00 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.60 | 45.0 | 3.85e-01 | 80.2% | 86.5% |
| 4ol9A02 | 1.10.1040.10 | Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 | 0.60 | 47.0 | 4.21e-01 | 87.2% | 96.9% |
| 4l7mA00 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.60 | 45.0 | 3.26e-01 | 89.5% | 26.8% |
| 1hciA03 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.60 | 45.0 | 4.07e-01 | 81.4% | 84.2% |
| 3bulA01 | 1.10.1240.10 | Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain | 0.59 | 44.0 | 4.38e-01 | 77.9% | 87.4% |
| 1wvtA00 | 1.20.1200.10 | Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like | 0.59 | 41.0 | 3.42e-01 | 72.1% | 79.7% |
| 4j8sA00 | 1.25.40.840 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › CCR4-NOT transcription complex subunit 1 TTP binding domain | 0.59 | 50.0 | 3.98e-01 | 95.3% | 50.6% |
| 2odmA00 | 1.10.287.750 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › SO2669-like | 0.58 | 44.0 | 4.55e-01 | 80.2% | 91.1% |
| 1nafA02 | 1.20.58.160 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.58 | 43.0 | 4.41e-01 | 81.4% | 95.3% |
| 2vwaA00 | 1.20.58.1330 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Plasmodium falciparum UIS3 membrane protein | 0.57 | 40.0 | 3.82e-01 | 70.9% | 66.7% |
| 2qk1A01 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.57 | 48.0 | 3.55e-01 | 95.3% | 34.7% |
| 3axjB01 | 1.20.58.190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 | 0.57 | 47.0 | 3.92e-01 | 91.9% | 74.2% |
| 3kavA00 | 1.20.1270.360 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.56 | 42.0 | 4.06e-01 | 82.6% | 68.6% |
| 2iaiA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.56 | 43.0 | 3.70e-01 | 81.4% | 64.7% |
| 3bh1A02 | 1.20.1570.10 | Mainly Alpha › Up-down Bundle › dip2346 fold › dip2346 domain like | 0.56 | 40.0 | 3.83e-01 | 74.4% | 83.2% |
| 3ttvA02 | 1.20.1370.20 | Mainly Alpha › Up-down Bundle › Hemocyanin, N-terminal domain › Catalase, four-helical domain | 0.55 | 41.0 | 3.87e-01 | 100.0% | 65.4% |
| 2yfkA01 | 3.40.50.1370 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Aspartate/ornithine carbamoyltransferase | 0.55 | 38.0 | 3.01e-01 | 88.4% | 32.8% |
| 2xppA00 | 1.20.930.10 | Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 | 0.55 | 46.0 | 4.00e-01 | 95.3% | 63.5% |
| 1sxjE03 | 1.20.272.10 | Mainly Alpha › Up-down Bundle › Zinc Finger, Delta Prime; domain 3 › | 0.55 | 43.0 | 4.17e-01 | 88.4% | 76.3% |
| 5c8aA01 | 1.10.1240.10 | Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain | 0.53 | 42.0 | 4.34e-01 | 89.5% | 96.2% |
| 4hehA01 | 1.10.1240.10 | Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain | 0.53 | 42.0 | 4.28e-01 | 89.5% | 91.6% |
| 2fd5A02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.51 | 41.0 | 3.62e-01 | 90.7% | 78.0% |
| 2raeA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.50 | 41.0 | 3.55e-01 | 90.7% | 70.8% |
ECOD (40)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3491110 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.70 | 54.0 | 4.98e-01 | 81.4% | 87.3% |
| 4011740 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.69 | 54.0 | 5.20e-01 | 84.9% | 84.0% |
| 4147954 | 604.34.1.1 ↗ | alpha bundles › Spectrin repeat-like › Helical bundle domain in arginine decarboxylase › Helical bundle domain in arginine decarboxylase › Arg_decarb_HB | 0.68 | 51.0 | 5.09e-01 | 80.2% | 83.3% |
| 4936976 | 633.10.1.2 ↗ | alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like › Bbp7-like | 0.68 | 52.0 | 4.91e-01 | 82.6% | 73.3% |
| 4306757 | 604.34.1.1 ↗ | alpha bundles › Spectrin repeat-like › Helical bundle domain in arginine decarboxylase › Helical bundle domain in arginine decarboxylase › Arg_decarb_HB | 0.67 | 53.0 | 4.97e-01 | 84.9% | 80.0% |
| 3924651 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.66 | 51.0 | 4.95e-01 | 81.4% | 90.5% |
| 3276944 | 604.12.1.2 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › Vta1 | 0.66 | 52.0 | 5.52e-01 | 84.9% | 96.0% |
| 4567001 | 604.34.1.1 ↗ | alpha bundles › Spectrin repeat-like › Helical bundle domain in arginine decarboxylase › Helical bundle domain in arginine decarboxylase › Arg_decarb_HB | 0.66 | 50.0 | 4.83e-01 | 80.2% | 78.9% |
| 3718498 | 604.6.1.0 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain | 0.64 | 49.0 | 4.91e-01 | 82.6% | 90.0% |
| 3659459 | 109.4.1.109 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Sel1 | 0.64 | 47.0 | 3.09e-01 | 77.9% | 19.2% |
| 4095580 | 604.34.1.1 ↗ | alpha bundles › Spectrin repeat-like › Helical bundle domain in arginine decarboxylase › Helical bundle domain in arginine decarboxylase › Arg_decarb_HB | 0.64 | 51.0 | 4.92e-01 | 84.9% | 78.9% |
| 3329196 | 604.6.1.1 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › GAT | 0.64 | 53.0 | 5.10e-01 | 93.0% | 91.0% |
| 3447256 | 603.1.1.17 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › SNARE | 0.63 | 50.0 | 3.62e-01 | 86.0% | 62.4% |
| 3496462 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.63 | 50.0 | 4.76e-01 | 86.0% | 89.0% |
| 4048456 | 604.34.1.1 ↗ | alpha bundles › Spectrin repeat-like › Helical bundle domain in arginine decarboxylase › Helical bundle domain in arginine decarboxylase › Arg_decarb_HB | 0.62 | 46.0 | 4.58e-01 | 77.9% | 83.3% |
| 5006787 | 150.2.1.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Cobalamin adenosyltransferase › Cobalamin adenosyltransferase › Cob_adeno_trans | 0.62 | 49.0 | 4.06e-01 | 86.0% | 85.8% |
| 3864682 | 109.6.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › Ras GEF › Ras GEF › RasGEF | 0.61 | 53.0 | 3.42e-01 | 95.3% | 23.0% |
| 3639996 | 109.4.1.819 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Sec8_C | 0.61 | 50.0 | 2.94e-01 | 91.9% | 19.8% |
| 3802382 | 604.6.1.0 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain | 0.61 | 51.0 | 4.30e-01 | 95.3% | 73.5% |
| 3387796 | 604.34.1.1 ↗ | alpha bundles › Spectrin repeat-like › Helical bundle domain in arginine decarboxylase › Helical bundle domain in arginine decarboxylase › Arg_decarb_HB | 0.61 | 45.0 | 4.46e-01 | 79.1% | 85.6% |
| 5075806 | 4995.1.1.1 ↗ | alpha arrays › Methionine synthase domain-like › Methionine synthase domain-like › Methionine synthase domain-like › B12-binding_2 | 0.60 | 49.0 | 5.05e-01 | 87.2% | 96.2% |
| 4997097 | 4995.1.1.1 ↗ | alpha arrays › Methionine synthase domain-like › Methionine synthase domain-like › Methionine synthase domain-like › B12-binding_2 | 0.60 | 47.0 | 5.03e-01 | 84.9% | 98.7% |
| 1180363 | 4995.1.1.1 ↗ | alpha arrays › Methionine synthase domain-like › Methionine synthase domain-like › Methionine synthase domain-like › B12-binding_2 | 0.60 | 44.0 | 4.71e-01 | 76.7% | 100.0% |
| 3608532 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.60 | 46.0 | 4.13e-01 | 83.7% | 82.1% |
| 4029425 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.59 | 45.0 | 4.59e-01 | 82.6% | 98.8% |
| 5012559 | 6028.1.1.0 ↗ | alpha bundles › Ribosome modulation factor › Ribosome modulation factor › Ribosome modulation factor | 0.59 | 36.0 | 3.83e-01 | 77.9% | 69.3% |
| 3615985 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.58 | 45.0 | 4.19e-01 | 83.7% | 86.4% |
| 3415622 | 180.1.1.1 ↗ | alpha bundles › Acid phosphatase/Vanadium-dependent haloperoxidase › Acid phosphatase/Vanadium-dependent haloperoxidase › Acid phosphatase/Vanadium-dependent haloperoxidase › PAP2 | 0.58 | 41.0 | 2.94e-01 | 73.3% | 67.3% |
| 3175202 | 109.4.1.266 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › XMAP215_CLASP_TOG | 0.58 | 48.0 | 3.38e-01 | 96.5% | 27.6% |
| 3255852 | 616.1.1.0 ↗ | alpha arrays › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain | 0.57 | 48.0 | 4.12e-01 | 93.0% | 76.4% |
| 5047897 | 4995.1.1.1 ↗ | alpha arrays › Methionine synthase domain-like › Methionine synthase domain-like › Methionine synthase domain-like › B12-binding_2 | 0.57 | 43.0 | 4.33e-01 | 79.1% | 87.1% |
| 4839189 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.56 | 46.0 | 4.17e-01 | 91.9% | 86.1% |
| 4983557 | 4995.1.1.1 ↗ | alpha arrays › Methionine synthase domain-like › Methionine synthase domain-like › Methionine synthase domain-like › B12-binding_2 | 0.56 | 41.0 | 4.29e-01 | 76.7% | 94.7% |
| 5004518 | 4995.1.1.1 ↗ | alpha arrays › Methionine synthase domain-like › Methionine synthase domain-like › Methionine synthase domain-like › B12-binding_2 | 0.56 | 40.0 | 4.21e-01 | 76.7% | 90.7% |
| 3507348 | 180.1.1.1 ↗ | alpha bundles › Acid phosphatase/Vanadium-dependent haloperoxidase › Acid phosphatase/Vanadium-dependent haloperoxidase › Acid phosphatase/Vanadium-dependent haloperoxidase › PAP2 | 0.55 | 42.0 | 3.01e-01 | 83.7% | 76.6% |
| 1392345 | 4995.1.1.2 ↗ | alpha arrays › Methionine synthase domain-like › Methionine synthase domain-like › Methionine synthase domain-like › AppA_4HB | 0.54 | 41.0 | 3.99e-01 | 84.9% | 76.0% |
| 3981539 | 532.2.1.1 ↗ | alpha arrays › Type III secretion system domain-like › Type III secretion system domains › Type III secretion system domains › HrpJ | 0.52 | 43.0 | 4.42e-01 | 90.7% | 100.0% |
| 3985103 | 532.2.1.1 ↗ | alpha arrays › Type III secretion system domain-like › Type III secretion system domains › Type III secretion system domains › HrpJ | 0.52 | 43.0 | 4.27e-01 | 93.0% | 90.0% |
| 3937836 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.51 | 42.0 | 2.76e-01 | 96.5% | 19.2% |
| 3298343 | 109.4.1.357 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Vac14_Fig4_bd | 0.51 | 41.0 | 3.61e-01 | 100.0% | 57.1% |