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S2_012_000_R2_scaffold_0_prodigal-single.1__X__X__00114
Bact-VirS2_012_000_R2_scaffold_0_prodigal-single.1__X__X__00114
Identity
- Kingdom:
- phage
Quality
81.5
mean pLDDT
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 164-230
Domain cluster:
representative
CATH (63)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3tklB01 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.84 | 59.0 | 6.13e-01 | 73.1% | 93.5% |
| 3nkzA00 | 1.20.58.380 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Flagellar protein flit. | 0.82 | 58.0 | 5.06e-01 | 76.1% | 50.5% |
| 1skvA00 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.82 | 59.0 | 6.02e-01 | 74.6% | 93.8% |
| 3vkgA12 | 1.10.287.2610 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.82 | 60.0 | 4.13e-01 | 77.6% | 24.2% |
| 1zbtA01 | 6.10.140.1950 | Special › Helix non-globular › Helix Hairpins › | 0.82 | 60.0 | 5.49e-01 | 76.1% | 63.9% |
| 3r84A00 | 1.10.287.3490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.81 | 59.0 | 5.51e-01 | 76.1% | 69.1% |
| 1z0jB00 | 4.10.860.20 | Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › Rabenosyn, Rab binding domain | 0.80 | 55.0 | 6.16e-01 | 74.6% | 92.2% |
| 2lw1A00 | 1.10.287.380 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Valyl-tRNA synthetase, C-terminal domain | 0.80 | 59.0 | 5.39e-01 | 77.6% | 77.6% |
| 1x4tA01 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.80 | 57.0 | 6.07e-01 | 74.6% | 100.0% |
| 1ydxA02 | 1.10.287.1120 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein | 0.79 | 58.0 | 5.22e-01 | 77.6% | 67.8% |
| 2f2gA00 | 1.20.910.10 | Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like | 0.79 | 70.0 | 4.88e-01 | 100.0% | 67.0% |
| 1urfA00 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.78 | 58.0 | 5.40e-01 | 77.6% | 65.4% |
| 1qsdA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.78 | 61.0 | 5.31e-01 | 85.1% | 85.3% |
| 2v0xA01 | 1.10.287.3160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.78 | 57.0 | 4.23e-01 | 77.6% | 32.7% |
| 2jdiG01 | 1.10.287.80 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain | 0.78 | 57.0 | 5.99e-01 | 77.6% | 85.2% |
| 3fppA03 | 6.10.140.1990 | Special › Helix non-globular › Helix Hairpins › | 0.76 | 55.0 | 4.99e-01 | 76.1% | 62.5% |
| 3l9fA02 | 6.10.140.1570 | Special › Helix non-globular › Helix Hairpins › | 0.76 | 55.0 | 5.21e-01 | 77.6% | 64.2% |
| 1h7cA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.76 | 68.0 | 5.88e-01 | 100.0% | 94.2% |
| 2y39A00 | 1.20.120.1490 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.75 | 54.0 | 4.59e-01 | 76.1% | 48.2% |
| 1jogA00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.75 | 61.0 | 4.82e-01 | 88.1% | 95.6% |
| 3h3mA00 | 1.20.58.380 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Flagellar protein flit. | 0.74 | 65.0 | 5.94e-01 | 100.0% | 76.4% |
| 4h63K00 | 1.10.287.3490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.73 | 54.0 | 4.75e-01 | 79.1% | 71.4% |
| 1wpaA01 | 6.10.140.340 | Special › Helix non-globular › Helix Hairpins › | 0.73 | 54.0 | 4.81e-01 | 80.6% | 68.7% |
| 1hr5A00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.73 | 49.0 | 5.47e-01 | 74.6% | 97.9% |
| 1hs7A00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.72 | 65.0 | 5.75e-01 | 100.0% | 75.3% |
| 4dkcB00 | 1.20.1250.80 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › Interleukin-34 | 0.72 | 62.0 | 4.63e-01 | 98.5% | 39.4% |
| 1w9cA00 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.72 | 63.0 | 4.08e-01 | 100.0% | 23.4% |
| 3qo8A01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.72 | 52.0 | 4.51e-01 | 77.6% | 50.0% |
| 1f6fA00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.71 | 61.0 | 4.41e-01 | 94.0% | 82.0% |
| 3m7gA02 | 1.10.8.1010 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.71 | 52.0 | 4.63e-01 | 77.6% | 58.9% |
| 3rm5B02 | 1.20.910.10 | Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like | 0.71 | 61.0 | 4.28e-01 | 100.0% | 36.2% |
| 1hciA03 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.71 | 63.0 | 5.17e-01 | 100.0% | 74.2% |
| 1o5hA00 | 1.20.120.680 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Formiminotetrahydrofolate cyclodeaminase monomer, up-and-down helical bundle | 0.70 | 61.0 | 4.40e-01 | 100.0% | 39.5% |
| 4iggA01 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.70 | 50.0 | 5.09e-01 | 77.6% | 77.6% |
| 1yxrA01 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.70 | 51.0 | 5.02e-01 | 85.1% | 71.6% |
| 1vf7A03 | 1.10.287.470 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.70 | 48.0 | 4.98e-01 | 71.6% | 98.3% |
| 3hr0B01 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.69 | 51.0 | 4.84e-01 | 77.6% | 65.8% |
| 4mrsA01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.69 | 59.0 | 3.75e-01 | 97.0% | 76.6% |
| 4cqiA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.68 | 60.0 | 5.17e-01 | 100.0% | 88.8% |
| 3rmgA00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.68 | 59.0 | 3.84e-01 | 100.0% | 21.7% |
| 1cxzB00 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.68 | 49.0 | 4.58e-01 | 77.6% | 65.1% |
| 1z6oA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.68 | 54.0 | 3.82e-01 | 88.1% | 29.7% |
| 7ymiZ01 | 1.10.287.740 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Photosystem II PsbZ, reaction centre | 0.68 | 48.0 | 5.04e-01 | 76.1% | 89.7% |
| 1zpyA00 | 6.10.140.1960 | Special › Helix non-globular › Helix Hairpins › | 0.67 | 52.0 | 4.74e-01 | 85.1% | 65.9% |
| 3syvA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.67 | 48.0 | 3.32e-01 | 77.6% | 22.9% |
| 1z6oM00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.66 | 58.0 | 4.23e-01 | 100.0% | 38.2% |
| 3axjB01 | 1.20.58.190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 | 0.66 | 56.0 | 4.42e-01 | 100.0% | 49.7% |
| 3vnxA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.66 | 57.0 | 4.15e-01 | 100.0% | 34.4% |
| 3r2kA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.65 | 56.0 | 4.34e-01 | 98.5% | 43.5% |
| 2yfaB01 | 1.20.1440.210 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.65 | 55.0 | 4.68e-01 | 98.5% | 88.2% |
| 2pusA04 | 6.10.140.300 | Special › Helix non-globular › Helix Hairpins › | 0.64 | 51.0 | 4.43e-01 | 100.0% | 54.6% |
| 4jvyB00 | 3.30.1370.10 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 | 0.64 | 55.0 | 3.96e-01 | 94.0% | 96.8% |
| 1qu3A04 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.64 | 55.0 | 4.32e-01 | 100.0% | 50.7% |
| 3ajmB02 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.64 | 56.0 | 4.45e-01 | 97.0% | 77.4% |
| 1gaxA02 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.64 | 55.0 | 3.87e-01 | 100.0% | 44.9% |
| 2kmfA01 | 1.20.58.810 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Photosystem II Pbs27 | 0.61 | 53.0 | 4.70e-01 | 100.0% | 91.2% |
| 1i1rB00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.60 | 50.0 | 3.87e-01 | 97.0% | 97.6% |
| 1b5lA00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.60 | 49.0 | 3.79e-01 | 98.5% | 40.1% |
| 2m6bA00 | 1.20.58.390 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Neurotransmitter-gated ion-channel transmembrane domain | 0.60 | 51.0 | 4.06e-01 | 100.0% | 47.3% |
| 2yqyA00 | 1.20.120.450 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › dinb family like domain | 0.60 | 46.0 | 3.76e-01 | 83.6% | 65.9% |
| 1m4rB00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.55 | 44.0 | 3.65e-01 | 100.0% | 45.4% |
| 4fjqA01 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.54 | 50.0 | 3.08e-01 | 100.0% | 30.2% |
| 4asvA00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.54 | 44.0 | 4.21e-01 | 98.5% | 78.5% |
ECOD (54)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3698361 | 5069.1.3.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits | 0.88 | 65.0 | 5.73e-01 | 77.6% | 54.7% |
| 3934022 | 616.1.1.0 ↗ | alpha arrays › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain | 0.85 | 76.0 | 6.59e-01 | 100.0% | 66.0% |
| 3906813 | 2004.1.1.26 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Kinesin | 0.85 | 63.0 | 3.90e-01 | 77.6% | 15.8% |
| 3356293 | 192.4.1.22 ↗ | alpha bundles › Long alpha-hairpin › Ribosomal protein L29 (L29p) › Ribosomal protein L29 (L29p) › PF26575 | 0.83 | 57.0 | 5.98e-01 | 70.1% | 78.3% |
| 3593583 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.82 | 61.0 | 4.75e-01 | 77.6% | 41.5% |
| 4028151 | 604.6.1.0 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain | 0.81 | 76.0 | 6.62e-01 | 100.0% | 76.8% |
| 5049284 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.81 | 58.0 | 4.72e-01 | 74.6% | 96.7% |
| 3785883 | 4177.1.1.97 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › PF30147 | 0.81 | 59.0 | 4.25e-01 | 77.6% | 28.6% |
| 3975665 | 5085.1.1.1 ↗ | a+b duplicates or obligate multimers › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) › OEP | 0.80 | 57.0 | 3.40e-01 | 74.6% | 18.4% |
| 3678791 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.79 | 58.0 | 4.01e-01 | 77.6% | 29.5% |
| 5047075 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.78 | 57.0 | 3.59e-01 | 77.6% | 19.4% |
| 3432510 | 616.1.1.0 ↗ | alpha arrays › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain | 0.78 | 61.0 | 6.19e-01 | 95.5% | 83.1% |
| 3574626 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.78 | 56.0 | 4.32e-01 | 74.6% | 51.4% |
| 4008609 | 1203.1.2.7 ↗ | alpha bundles › Shroom domain 2 › Shroom domain 2 › Human SD2 › GNVR | 0.78 | 68.0 | 5.42e-01 | 100.0% | 55.7% |
| 3578422 | 109.4.1.1552 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF28736 | 0.78 | 67.0 | 4.65e-01 | 95.5% | 33.2% |
| 3166260 | 1.1.7.123 ↗ | beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › PF25885 | 0.78 | 57.0 | 4.53e-01 | 77.6% | 62.3% |
| 4283760 | 1203.1.2.7 ↗ | alpha bundles › Shroom domain 2 › Shroom domain 2 › Human SD2 › GNVR | 0.77 | 68.0 | 5.37e-01 | 100.0% | 54.3% |
| 3250375 | 192.1.1.0 ↗ | alpha bundles › Long alpha-hairpin › GreA transcript cleavage protein, N-terminal domain › GreA transcript cleavage protein, N-terminal domain | 0.77 | 56.0 | 5.43e-01 | 77.6% | 78.7% |
| 5077093 | 4323.1.1.0 ↗ | alpha bundles › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C | 0.76 | 56.0 | 4.43e-01 | 77.6% | 48.9% |
| 3375952 | 6155.1.1.1 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › MtN3_slv | 0.76 | 67.0 | 5.21e-01 | 100.0% | 47.3% |
| 3971349 | 5086.1.1.84 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_MFP_RND | 0.76 | 54.0 | 5.68e-01 | 76.1% | 90.0% |
| 3477822 | 1147.1.1.1 ↗ | alpha bundles › RNA polymerase II elongation factor ELL2 C-terminal domain › RNA polymerase II elongation factor ELL2 C-terminal domain › RNA polymerase II elongation factor ELL2 C-terminal domain › Occludin_ELL | 0.76 | 58.0 | 4.70e-01 | 82.1% | 48.0% |
| 4258322 | 5086.1.1.189 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_CzcB | 0.75 | 57.0 | 5.69e-01 | 82.1% | 90.0% |
| 4376020 | 5059.1.1.0 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter | 0.75 | 65.0 | 5.52e-01 | 100.0% | 59.3% |
| 4090348 | 2004.1.1.29 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD | 0.74 | 66.0 | 4.31e-01 | 97.0% | 30.0% |
| 4010267 | 192.8.1.131 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › GNVR | 0.74 | 66.0 | 5.31e-01 | 100.0% | 58.5% |
| 3946576 | 5086.1.1.66 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › GNVR | 0.74 | 65.0 | 5.17e-01 | 98.5% | 56.3% |
| 3939646 | 206.1.1.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase | 0.74 | 53.0 | 2.97e-01 | 76.1% | 6.1% |
| 3443484 | 616.1.1.0 ↗ | alpha arrays › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain | 0.74 | 62.0 | 6.05e-01 | 100.0% | 85.1% |
| 3875112 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.74 | 66.0 | 4.10e-01 | 97.0% | 55.6% |
| 55069 | 603.1.1.1 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin | 0.73 | 66.0 | 5.60e-01 | 100.0% | 77.1% |
| 3212065 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.72 | 53.0 | 4.20e-01 | 77.6% | 38.5% |
| 3844040 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.72 | 53.0 | 5.41e-01 | 77.6% | 80.0% |
| 3420557 | 5069.1.1.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes | 0.72 | 63.0 | 4.67e-01 | 97.0% | 85.9% |
| 4414655 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.71 | 57.0 | 4.06e-01 | 92.5% | 31.1% |
| 3796175 | 192.15.1.99 ↗ | alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains › PF31025 | 0.71 | 50.0 | 5.50e-01 | 74.6% | 100.0% |
| 4947713 | 5059.1.1.0 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter | 0.71 | 61.0 | 5.20e-01 | 100.0% | 59.1% |
| 4935430 | 5059.1.1.1 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA | 0.70 | 62.0 | 5.32e-01 | 100.0% | 62.9% |
| 3269731 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.70 | 61.0 | 5.17e-01 | 100.0% | 83.5% |
| 4947819 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.69 | 61.0 | 4.43e-01 | 98.5% | 57.8% |
| 5028679 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.69 | 49.0 | 4.34e-01 | 77.6% | 59.2% |
| 3385717 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.68 | 59.0 | 4.44e-01 | 98.5% | 93.5% |
| 5071598 | 109.3.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat | 0.68 | 58.0 | 4.65e-01 | 100.0% | 51.7% |
| 4938696 | 3883.1.1.1 ↗ | alpha bundles › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-OH_P_transf | 0.66 | 57.0 | 4.64e-01 | 100.0% | 51.1% |
| 4997360 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.66 | 56.0 | 3.92e-01 | 100.0% | 28.3% |
| 3705411 | 109.4.1.777 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.65 | 57.0 | 3.60e-01 | 100.0% | 28.7% |
| 3973899 | 5086.1.1.92 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_AprE | 0.65 | 48.0 | 3.83e-01 | 80.6% | 71.7% |
| 2163538 | 150.1.2.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase | 0.64 | 57.0 | 4.02e-01 | 100.0% | 45.3% |
| 4029600 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.64 | 57.0 | 4.33e-01 | 100.0% | 43.3% |
| 3744381 | 4106.1.1.1 ↗ | few secondary structure elements › Zinc hairpin stack › Zinc hairpin stack › Zinc hairpin stack › DHHC | 0.64 | 50.0 | 3.71e-01 | 86.6% | 37.9% |
| 3177692 | 109.4.1.110 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Mad3_BUB1_I | 0.62 | 50.0 | 3.45e-01 | 94.0% | 26.1% |
| 3740547 | 5086.1.1.87 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › ING | 0.62 | 44.0 | 3.84e-01 | 77.6% | 47.3% |
| 3936693 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.61 | 51.0 | 4.60e-01 | 100.0% | 79.0% |
| 3362472 | 605.1.1.132 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › DUF641 | 0.59 | 52.0 | 4.41e-01 | 98.5% | 69.1% |
D2
medium
residues 3-46_65-142
Domain cluster:
representative
CATH (32)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1hu3A00 | 1.25.40.180 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.67 | 46.0 | 3.89e-01 | 100.0% | 42.2% |
| 2oi8A00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.62 | 56.0 | 4.70e-01 | 98.4% | 79.8% |
| 4zvaA00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.61 | 46.0 | 4.37e-01 | 91.0% | 65.1% |
| 3c02A00 | 1.20.1080.10 | Mainly Alpha › Up-down Bundle › Glycerol uptake facilitator protein › Glycerol uptake facilitator protein. | 0.61 | 48.0 | 3.89e-01 | 85.2% | 91.7% |
| 3g5uA01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.60 | 51.0 | 3.16e-01 | 91.0% | 79.1% |
| 2rasA01 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.58 | 51.0 | 4.43e-01 | 98.4% | 83.2% |
| 2f2bA00 | 1.20.1080.10 | Mainly Alpha › Up-down Bundle › Glycerol uptake facilitator protein › Glycerol uptake facilitator protein. | 0.57 | 44.0 | 3.64e-01 | 85.2% | 92.2% |
| 1o5hA00 | 1.20.120.680 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Formiminotetrahydrofolate cyclodeaminase monomer, up-and-down helical bundle | 0.56 | 39.0 | 3.35e-01 | 71.3% | 78.5% |
| 1s2xA00 | 1.20.190.30 | Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › CAG pathogenicity island protein, CagZ | 0.56 | 47.0 | 4.17e-01 | 93.4% | 91.1% |
| 4udsA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.55 | 49.0 | 4.29e-01 | 99.2% | 84.7% |
| 1yxrA01 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.55 | 32.0 | 3.88e-01 | 95.1% | 93.2% |
| 3qbmB00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.55 | 47.0 | 4.11e-01 | 97.5% | 77.7% |
| 6xxvC00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.54 | 42.0 | 4.40e-01 | 82.0% | 97.3% |
| 4mo7A02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.54 | 44.0 | 4.21e-01 | 87.7% | 78.9% |
| 2ehwA00 | 6.10.140.1220 | Special › Helix non-globular › Helix Hairpins › | 0.54 | 36.0 | 3.74e-01 | 73.8% | 73.0% |
| 2g7sA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.54 | 48.0 | 4.13e-01 | 98.4% | 89.5% |
| 2yevA03 | 1.20.120.80 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle | 0.53 | 42.0 | 3.72e-01 | 86.1% | 95.7% |
| 3rkoG00 | 1.10.287.3510 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.53 | 33.0 | 3.64e-01 | 95.1% | 76.0% |
| 6t0bc02 | 1.20.120.80 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle | 0.53 | 42.0 | 3.67e-01 | 86.1% | 96.3% |
| 3himA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.53 | 47.0 | 4.06e-01 | 98.4% | 90.5% |
| 1y4cA03 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.53 | 39.0 | 4.07e-01 | 93.4% | 83.2% |
| 1tjlA00 | 1.20.120.910 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › DksA, coiled-coil domain | 0.53 | 37.0 | 3.49e-01 | 72.1% | 82.1% |
| 2yfaA02 | 1.20.1440.210 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.52 | 39.0 | 3.98e-01 | 86.9% | 81.9% |
| 4dloB02 | 1.25.40.610 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.52 | 37.0 | 3.77e-01 | 100.0% | 76.1% |
| 4mndA02 | 1.20.120.1760 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CDP-alcohol phosphotransferase transmembrane (TM) domain | 0.52 | 44.0 | 3.84e-01 | 100.0% | 59.7% |
| 8ek4A01 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.52 | 42.0 | 4.15e-01 | 87.7% | 91.0% |
| 6yz2A01 | 1.20.120.350 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C | 0.52 | 38.0 | 3.84e-01 | 93.4% | 77.5% |
| 3godB02 | 1.20.120.920 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CRISPR-associated endonuclease Cas1, C-terminal domain | 0.51 | 39.0 | 3.37e-01 | 82.0% | 51.4% |
| 3ajmB02 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.51 | 37.0 | 3.66e-01 | 91.8% | 69.2% |
| 4id0A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.51 | 37.0 | 3.90e-01 | 87.7% | 82.1% |
| 3m0fB02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.51 | 37.0 | 3.77e-01 | 76.2% | 96.7% |
| 4mk3A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.51 | 39.0 | 4.02e-01 | 88.5% | 86.1% |
ECOD (20)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3789289 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.65 | 49.0 | 4.13e-01 | 97.5% | 46.2% |
| 3600271 | 1075.1.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain | 0.64 | 53.0 | 4.21e-01 | 91.0% | 84.3% |
| 4181969 | 4967.1.1.0 ↗ | alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases | 0.58 | 52.0 | 4.73e-01 | 100.0% | 74.5% |
| 4025205 | 601.19.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein | 0.56 | 42.0 | 3.92e-01 | 78.7% | 86.0% |
| 3585980 | 109.4.1.727 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › DUF913 | 0.55 | 46.0 | 3.19e-01 | 93.4% | 60.9% |
| 4022845 | 1065.1.1.1 ↗ | alpha bundles › SPX domain › SPX domain › SPX domain › SPX | 0.54 | 47.0 | 3.89e-01 | 96.7% | 70.9% |
| 3992327 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.53 | 41.0 | 3.49e-01 | 100.0% | 47.0% |
| 5078867 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.53 | 37.0 | 4.17e-01 | 84.4% | 95.6% |
| 5017862 | 601.7.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain | 0.53 | 37.0 | 3.72e-01 | 71.3% | 87.2% |
| 3545225 | 109.4.1.536 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Mei4 | 0.53 | 47.0 | 3.56e-01 | 100.0% | 54.1% |
| 5074225 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.53 | 37.0 | 4.21e-01 | 95.9% | 100.0% |
| 4878251 | 601.7.1.7 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › NTase_sub_bind | 0.52 | 36.0 | 3.57e-01 | 71.3% | 82.0% |
| 4980095 | 310.2.1.0 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF | 0.52 | 42.0 | 4.43e-01 | 86.1% | 100.0% |
| 3715231 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.52 | 43.0 | 3.77e-01 | 89.3% | 77.3% |
| 3798573 | 601.1.1.5 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › CAS_C | 0.52 | 41.0 | 3.83e-01 | 83.6% | 79.4% |
| 5069603 | 601.18.1.30 ↗ | alpha bundles › Four-helical up-and-down bundle › Oxygen-evolving enhancer protein 3 › Oxygen-evolving enhancer protein 3 › Cytochrom_C_asm | 0.52 | 39.0 | 3.93e-01 | 94.3% | 77.6% |
| 54287 | 633.10.1.0 ↗ | alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like | 0.52 | 39.0 | 4.02e-01 | 92.6% | 84.3% |
| 3519218 | 3861.1.1.1 ↗ | alpha bundles › Mitochondrial translocator protein (TSPO) › Mitochondrial translocator protein (TSPO) › Mitochondrial translocator protein (TSPO) › TspO_MBR | 0.51 | 38.0 | 3.46e-01 | 91.8% | 57.6% |
| 138422 | 109.1.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Glutathione S-transferase (GST)-C › Glutathione S-transferase (GST)-C | 0.51 | 37.0 | 3.74e-01 | 76.2% | 95.2% |
| 3444036 | 601.1.1.91 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › DUF1218 | 0.50 | 35.0 | 3.47e-01 | 70.5% | 78.4% |