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S2_012_000_R2_scaffold_0_prodigal-single.1__X__X__00171

Bact-Vir

S2_012_000_R2_scaffold_0_prodigal-single.1__X__X__00171

Identity

Kingdom:
phage

Quality

88.9 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 7-112
PDB
Domain cluster: representative
CATH (18)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2zgdA00 1.25.40.20 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain 0.81 65.0 6.85e-01 95.3% 91.8%
3ljnA00 1.25.40.20 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain 0.81 67.0 4.69e-01 98.1% 30.3%
1dcqA02 1.25.40.20 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain 0.81 74.0 6.36e-01 99.1% 65.6%
2f37A00 1.25.40.20 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain 0.73 66.0 5.01e-01 100.0% 66.8%
4n5qA00 1.25.40.20 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain 0.71 64.0 4.87e-01 100.0% 64.7%
4rlyA00 1.25.40.20 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain 0.69 64.0 4.48e-01 100.0% 40.6%
5mdtA00 1.25.40.90 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.66 60.0 5.30e-01 100.0% 90.1%
1ldjA04 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.61 50.0 4.95e-01 89.6% 87.0%
7ep3A01 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.60 52.0 4.09e-01 97.2% 50.2%
2pfdA03 1.20.120.680 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Formiminotetrahydrofolate cyclodeaminase monomer, up-and-down helical bundle 0.60 44.0 3.56e-01 76.4% 83.3%
3vw5A00 1.50.10.10 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › 0.60 53.0 3.65e-01 100.0% 42.2%
3vwaA03 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.58 51.0 3.72e-01 98.1% 37.2%
4epzA00 1.25.40.810 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › UpxZ 0.55 45.0 4.03e-01 88.7% 69.5%
2fx0A02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.55 38.0 3.59e-01 72.6% 72.0%
2rekA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.54 47.0 4.09e-01 100.0% 83.1%
4y6cA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.54 46.0 3.69e-01 94.3% 50.5%
4y97D00 1.10.3200.20 Mainly Alpha › Orthogonal Bundle › Hypothetical protein af0941 › DNA Polymerase alpha, zinc finger 0.51 41.0 3.51e-01 88.7% 89.3%
4hojA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.50 38.0 3.91e-01 84.0% 86.4%
ECOD (26)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3621664 109.3.1.2 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank,Ank_2 0.80 76.0 5.95e-01 100.0% 55.1%
3727140 109.3.1.96 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank+Ank_2+Ank_4 0.79 73.0 5.48e-01 98.1% 45.4%
3416970 109.3.1.2 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank,Ank_2 0.79 73.0 6.25e-01 98.1% 68.6%
3574736 109.3.1.8 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank_2 0.79 74.0 6.02e-01 99.1% 78.9%
3843268 109.3.1.2 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank,Ank_2 0.78 72.0 5.60e-01 98.1% 51.6%
1204125 109.3.1.1 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank 0.75 68.0 5.15e-01 100.0% 67.6%
None — 0.74 67.0 4.02e-01 100.0% 25.2%
None — 0.73 66.0 4.06e-01 100.0% 27.4%
None — 0.73 66.0 4.06e-01 100.0% 27.6%
3249784 109.3.1.96 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank+Ank_2+Ank_4 0.73 68.0 4.88e-01 100.0% 49.8%
4022094 109.3.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.71 45.0 3.77e-01 71.7% 37.8%
3478421 109.3.1.1 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank 0.70 56.0 4.80e-01 83.0% 68.8%
3689586 109.3.1.20 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank_2,Ank_4 0.69 63.0 4.83e-01 100.0% 55.6%
3275350 109.3.1.96 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank+Ank_2+Ank_4 0.69 59.0 5.47e-01 95.3% 74.1%
3999942 109.4.1.549 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SAPS 0.68 61.0 3.97e-01 98.1% 26.8%
3734558 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.68 60.0 3.45e-01 100.0% 19.1%
4014545 109.3.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.64 54.0 4.33e-01 93.4% 58.1%
3597482 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.64 50.0 5.09e-01 85.8% 84.8%
5080824 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.61 54.0 4.58e-01 99.1% 60.0%
4215090 131.1.1.12 ↗ alpha complex topology › PDEase-like › HD-domain/PDEase-like › HD-domain/PDEase-like › HD_4 0.57 49.0 3.98e-01 95.3% 57.1%
3598195 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.57 50.0 4.60e-01 100.0% 91.4%
3993403 616.1.1.26 ↗ alpha arrays › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › NPP-6_helical 0.53 43.0 3.84e-01 89.6% 80.6%
3736320 109.4.1.194 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_10 0.53 46.0 3.36e-01 100.0% 40.3%
3234580 3883.1.1.1 ↗ alpha bundles › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-OH_P_transf 0.53 42.0 3.48e-01 86.8% 71.3%
3269617 604.6.1.0 ↗ alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain 0.52 46.0 4.21e-01 97.2% 91.4%
3936714 2484.1.1.67 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3 0.52 38.0 3.46e-01 77.4% 75.2%
D2 medium residues 113-202
PDB
Domain cluster: representative
CATH (43)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
7kb2B01 1.25.40.20 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain 0.80 58.0 4.54e-01 91.1% 37.9%
1qgrA00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.66 58.0 3.36e-01 100.0% 17.0%
1f59A00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.65 57.0 3.71e-01 100.0% 35.9%
6wm2P02 1.25.40.150 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › V-type ATPase, subunit H, C-terminal domain 0.64 51.0 4.80e-01 90.0% 70.6%
5vjcA00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.64 57.0 4.09e-01 100.0% 62.2%
1ho8A02 1.25.40.150 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › V-type ATPase, subunit H, C-terminal domain 0.63 54.0 5.07e-01 94.4% 79.5%
8h6rA01 1.20.930.10 Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 0.63 52.0 5.32e-01 90.0% 100.0%
3l9tA01 1.10.1240.70 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › 0.63 44.0 4.63e-01 86.7% 79.5%
2vxgA02 1.10.220.100 Mainly Alpha › Orthogonal Bundle › Annexin V; domain 1 › conserved c-terminal region of ge- 1 0.63 53.0 5.44e-01 97.8% 98.8%
2pusA04 6.10.140.300 Special › Helix non-globular › Helix Hairpins › 0.62 45.0 4.24e-01 75.6% 80.6%
4uucA00 1.25.40.20 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain 0.62 58.0 4.23e-01 100.0% 43.9%
1n4kA02 1.25.10.30 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › IP3 receptor type 1 binding core, RIH domain 0.61 53.0 4.54e-01 97.8% 74.3%
6tblB01 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.61 53.0 5.00e-01 96.7% 99.1%
3c2gA02 1.10.10.1630 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Sys-1 C-terminal domain-like 0.60 43.0 4.86e-01 85.6% 100.0%
2xppA00 1.20.930.10 Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 0.59 50.0 4.46e-01 97.8% 65.0%
3vprA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.59 50.0 4.30e-01 94.4% 74.5%
3au3A00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.59 50.0 3.56e-01 97.8% 37.2%
8d0vA01 1.50.10.10 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › 0.58 47.0 3.17e-01 91.1% 22.5%
2ra1A03 1.20.58.770 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.58 39.0 4.46e-01 80.0% 100.0%
2dnxA00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.58 44.0 3.98e-01 82.2% 83.1%
3lxzB02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.58 49.0 4.37e-01 97.8% 75.4%
1aluA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.58 42.0 3.56e-01 77.8% 51.6%
3gwjA02 1.10.1280.10 Mainly Alpha › Orthogonal Bundle › di-copper center containing domain from catechol oxidase › Di-copper center containing domain from catechol oxidase 0.57 40.0 3.03e-01 74.4% 51.9%
2yfaA02 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.57 42.0 3.87e-01 78.9% 72.4%
2af7D00 1.20.1290.10 Mainly Alpha › Up-down Bundle › AhpD-like › AhpD-like 0.56 49.0 4.51e-01 100.0% 95.0%
3hl6A02 1.20.58.700 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.56 42.0 3.97e-01 82.2% 68.7%
2ibdA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.56 46.0 4.03e-01 94.4% 75.5%
3kbtA00 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.55 40.0 2.88e-01 77.8% 25.4%
1r5aA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.55 46.0 4.14e-01 97.8% 72.8%
1e2aA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.54 40.0 3.91e-01 81.1% 96.1%
3axjB01 1.20.58.190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 0.53 44.0 3.80e-01 96.7% 82.6%
2i9cA01 1.25.40.70 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Phosphatidylinositol 3-kinase, accessory domain (PIK) 0.53 44.0 4.21e-01 95.6% 97.3%
2lvfA00 1.10.110.10 Mainly Alpha › Orthogonal Bundle › Hydrophobic Seed Protein › Plant lipid-transfer and hydrophobic proteins 0.53 43.0 4.02e-01 92.2% 85.1%
1is9A00 1.50.10.10 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › 0.53 45.0 3.09e-01 98.9% 27.9%
2c12A01 1.10.540.10 Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain 0.52 41.0 3.72e-01 86.7% 75.6%
6wb9201 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.52 41.0 2.93e-01 90.0% 27.0%
6elqA01 1.20.1270.30 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.52 39.0 3.14e-01 92.2% 41.5%
3cuxA02 1.20.1220.12 Mainly Alpha › Up-down Bundle › Malate Synthase G; Chain: A; Domain 4 › Malate synthase, domain III 0.51 42.0 3.87e-01 93.3% 87.6%
7b7tA01 1.20.1270.30 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.51 38.0 3.10e-01 87.8% 43.5%
6vw7B03 1.20.1440.230 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain 0.51 39.0 4.06e-01 84.4% 95.2%
2wauA02 1.20.58.830 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.50 41.0 3.76e-01 90.0% 95.1%
1gs0A01 1.20.142.10 Mainly Alpha › Up-down Bundle › Poly(ADP-ribose) Polymerase; domain 1 › Poly(ADP-ribose) polymerase, regulatory domain 0.50 35.0 3.19e-01 92.2% 51.2%
2b0hA01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.50 41.0 3.74e-01 92.2% 82.8%
ECOD (41)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3794102 5067.1.1.5 ↗ alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Sterol-sensing 0.70 47.0 3.69e-01 70.0% 50.3%
4011096 109.3.1.166 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank, Ank_2, Ank_3 0.68 62.0 4.21e-01 100.0% 35.5%
3797620 5067.1.1.0 ↗ alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain 0.67 46.0 3.52e-01 70.0% 47.2%
3806870 611.3.1.0 ↗ alpha bundles › N-cbl like › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 0.67 58.0 5.70e-01 97.8% 95.0%
4171508 109.4.1.117 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › STAG,SCD 0.65 55.0 3.64e-01 94.4% 46.7%
3430042 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.65 57.0 3.99e-01 100.0% 54.1%
3889085 109.4.1.651 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Arm_2 0.64 52.0 3.58e-01 90.0% 25.6%
3853189 109.4.1.910 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HEAT_MROH2B_C 0.64 57.0 3.91e-01 98.9% 35.6%
3735292 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.64 57.0 3.87e-01 100.0% 34.0%
3865185 611.3.1.1 ↗ alpha bundles › N-cbl like › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 › Med26 0.64 50.0 4.92e-01 90.0% 80.0%
3225466 109.3.1.2 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank,Ank_2 0.63 60.0 4.92e-01 100.0% 64.7%
3381980 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.63 52.0 4.16e-01 100.0% 45.0%
3737968 611.3.1.1 ↗ alpha bundles › N-cbl like › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 › Med26 0.63 51.0 5.35e-01 93.3% 98.8%
3489430 109.3.1.166 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank, Ank_2, Ank_3 0.63 59.0 4.23e-01 100.0% 40.9%
4349221 109.3.1.166 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank, Ank_2, Ank_3 0.63 58.0 4.26e-01 100.0% 47.6%
3915552 109.4.1.659 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PELP1_HEAT 0.63 55.0 3.51e-01 100.0% 34.4%
3465076 109.3.1.2 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank,Ank_2 0.63 59.0 4.13e-01 100.0% 43.6%
135058 109.3.1.2 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank,Ank_2 0.62 59.0 4.19e-01 100.0% 41.7%
3679557 611.3.1.1 ↗ alpha bundles › N-cbl like › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 › Med26 0.62 49.0 5.05e-01 88.9% 89.4%
3678357 109.4.1.22 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Adaptin_N 0.62 55.0 3.33e-01 100.0% 18.7%
3708195 109.4.1.1276 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › FAT, HEAT_ATR 0.62 55.0 3.81e-01 100.0% 45.2%
3436215 611.3.1.1 ↗ alpha bundles › N-cbl like › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 › Med26 0.62 55.0 4.66e-01 97.8% 64.1%
5013043 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.62 54.0 4.11e-01 100.0% 60.4%
3739247 109.4.1.482 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › V-ATPase_H_C 0.62 51.0 4.55e-01 95.6% 63.1%
3889741 109.4.1.2 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Arm 0.61 52.0 3.30e-01 93.3% 18.1%
3831252 611.3.1.1 ↗ alpha bundles › N-cbl like › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 › Med26 0.61 54.0 4.97e-01 97.8% 86.4%
4846601 603.5.1.1 ↗ alpha bundles › STAT-like › FlgN-like › FlgN-like › FlgN 0.59 44.0 4.04e-01 80.0% 80.3%
3897356 603.1.1.17 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins › SNARE 0.59 50.0 3.94e-01 97.8% 73.3%
4019164 109.3.1.218 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank_KRIT1 0.59 54.0 4.21e-01 100.0% 54.6%
3391879 109.3.1.2 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank,Ank_2 0.59 54.0 4.53e-01 100.0% 61.4%
3716393 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.59 51.0 3.47e-01 98.9% 36.2%
3656261 109.4.1.957 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_TTI1_N 0.57 48.0 3.97e-01 100.0% 82.2%
5029847 192.29.1.0 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.56 42.0 4.52e-01 87.8% 96.0%
3182158 5050.1.1.9 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.55 41.0 3.05e-01 77.8% 91.5%
5079588 310.2.1.0 ↗ a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.54 38.0 3.85e-01 73.3% 97.8%
3194507 109.4.1.350 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › ELYS 0.54 47.0 3.70e-01 100.0% 60.0%
4254412 7516.1.1.117 ↗ a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2, Cellulose_synt, Glyco_trans_2_3 0.53 47.0 2.89e-01 100.0% 54.5%
3618872 4271.1.1.3 ↗ alpha complex topology › PriB N-terminal domain-like › PriB N-terminal domain-like › PriB N-terminal domain-like › DNA_primase_lrg_N 0.52 41.0 3.15e-01 88.9% 83.0%
3186192 5050.1.1.1 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr 0.51 39.0 2.95e-01 84.4% 44.3%
3935935 4271.1.1.3 ↗ alpha complex topology › PriB N-terminal domain-like › PriB N-terminal domain-like › PriB N-terminal domain-like › DNA_primase_lrg_N 0.51 42.0 3.18e-01 93.3% 84.3%
3895504 150.3.1.13 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › 4-helical cytokines › 4-helical cytokine › Leptin 0.50 38.0 3.27e-01 82.2% 76.0%
D3 medium residues 203-268
PDB
Domain cluster: representative
CATH (37)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
8gpvA01 1.25.60.10 Mainly Alpha › Alpha Horseshoe › MgtE N-terminal fold › MgtE N-terminal domain-like 0.73 60.0 4.84e-01 100.0% 46.5%
3hjlA02 1.10.220.30 Mainly Alpha › Orthogonal Bundle › Annexin V; domain 1 › Flagellar motor switch protein FliG, alpha-alpha superhelical domain 0.73 61.0 5.18e-01 98.5% 56.6%
8gpsA01 1.25.60.10 Mainly Alpha › Alpha Horseshoe › MgtE N-terminal fold › MgtE N-terminal domain-like 0.72 58.0 5.06e-01 100.0% 57.1%
2yvyA01 1.25.60.10 Mainly Alpha › Alpha Horseshoe › MgtE N-terminal fold › MgtE N-terminal domain-like 0.71 64.0 5.13e-01 100.0% 52.8%
3rbtA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.71 61.0 5.12e-01 100.0% 87.2%
2qezA02 1.10.220.70 Mainly Alpha › Orthogonal Bundle › Annexin V; domain 1 › lyase 0.67 53.0 4.87e-01 90.9% 66.7%
3wd6A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.66 57.0 4.82e-01 100.0% 87.3%
1z21A00 1.10.10.1000 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Type III secretion system virulence factor YopR, core domain 0.66 54.0 4.85e-01 93.9% 94.8%
5c8aA01 1.10.1240.10 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain 0.66 53.0 5.08e-01 89.4% 97.4%
4hehA01 1.10.1240.10 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain 0.66 55.0 5.14e-01 95.5% 96.4%
2qyuA02 1.25.40.300 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Putative secreted effector protein 0.65 55.0 4.07e-01 100.0% 55.9%
1oj6A00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.65 53.0 4.21e-01 93.9% 61.2%
1lkvX02 1.10.220.30 Mainly Alpha › Orthogonal Bundle › Annexin V; domain 1 › Flagellar motor switch protein FliG, alpha-alpha superhelical domain 0.64 50.0 4.13e-01 95.5% 44.7%
2af7D00 1.20.1290.10 Mainly Alpha › Up-down Bundle › AhpD-like › AhpD-like 0.61 52.0 4.39e-01 100.0% 89.3%
1bucA01 1.10.540.10 Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain 0.61 50.0 4.19e-01 95.5% 75.6%
1np7A02 1.25.40.80 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.61 52.0 4.39e-01 100.0% 64.7%
2oifB00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.60 48.0 3.80e-01 92.4% 80.1%
5jrcA00 1.20.58.2140 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.60 51.0 3.80e-01 100.0% 74.7%
2i0mA02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.59 47.0 4.13e-01 89.4% 97.0%
4hi8A00 1.25.40.20 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain 0.59 50.0 3.81e-01 100.0% 41.8%
4fqnC00 1.20.1160.20 Mainly Alpha › Up-down Bundle › Paired amphipathic helix 2 (pah2 repeat) › 0.59 49.0 4.55e-01 95.5% 85.9%
4malA00 1.20.58.2200 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.59 43.0 4.50e-01 84.8% 88.1%
2rfqB01 1.10.540.10 Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain 0.58 47.0 4.14e-01 95.5% 78.0%
3sz7A00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.57 50.0 3.89e-01 100.0% 48.3%
1hx8A02 1.20.58.150 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › ANTH domain 0.56 47.0 4.03e-01 100.0% 100.0%
3g2eB00 3.40.920.10 Alpha Beta › 3-Layer(aba) Sandwich › Pyruvate-ferredoxin Oxidoreductase; domain 3 › Pyruvate-ferredoxin oxidoreductase, PFOR, domain III 0.55 47.0 3.47e-01 97.0% 87.0%
3eslA02 1.25.40.930 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.55 48.0 4.03e-01 100.0% 63.0%
3ma5A00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.55 48.0 4.35e-01 100.0% 73.3%
2ptfB02 1.20.58.290 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hypothetical membrane protein ta0354_69_121. 0.54 42.0 4.50e-01 86.4% 100.0%
7z7vF03 1.20.1440.230 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain 0.54 42.0 3.92e-01 87.9% 71.6%
3eabE00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.54 42.0 3.88e-01 87.9% 95.3%
2nr4A02 1.20.58.290 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hypothetical membrane protein ta0354_69_121. 0.53 40.0 4.17e-01 83.3% 94.8%
3n2oA03 1.20.58.930 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.52 41.0 3.72e-01 90.9% 89.6%
3on3B00 3.40.920.10 Alpha Beta › 3-Layer(aba) Sandwich › Pyruvate-ferredoxin Oxidoreductase; domain 3 › Pyruvate-ferredoxin oxidoreductase, PFOR, domain III 0.51 42.0 3.24e-01 98.5% 92.6%
1k78I00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.51 36.0 3.85e-01 75.8% 91.4%
1rtwB00 1.20.910.10 Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like 0.50 45.0 3.16e-01 100.0% 68.3%
2yjkC00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.50 39.0 3.07e-01 86.4% 85.4%
ECOD (24)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3744228 109.4.1.322 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Nse5 0.72 62.0 3.98e-01 100.0% 33.1%
5015099 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.72 64.0 4.49e-01 100.0% 32.9%
326759 109.13.1.1 ↗ alpha superhelices › Repetitive alpha hairpins › MgtE N-terminal domain-like › MgtE N-terminal domain-like › MgtE_N 0.71 64.0 5.11e-01 100.0% 52.0%
3644550 109.4.1.16 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PUF 0.70 60.0 3.75e-01 98.5% 25.3%
4021533 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.69 59.0 3.74e-01 100.0% 20.5%
3893810 4207.1.1.25 ↗ alpha duplicates or obligate multimers › Mediator hinge subcomplex-like › Mediator hinge subcomplex-like › RNA polymerase II holoenzyme component SRB7 (MED21) › MINAR1_N 0.67 53.0 4.78e-01 89.4% 100.0%
3178430 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.67 57.0 4.03e-01 100.0% 53.4%
3440497 109.4.1.494 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Npa1 0.65 55.0 4.26e-01 100.0% 60.0%
4339703 531.1.1.1 ↗ alpha arrays › Domains of FliG › C-terminal domain of FliG › C-terminal domain of FliG › FliG_C 0.64 52.0 4.13e-01 97.0% 42.9%
4004092 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.63 54.0 4.58e-01 100.0% 91.3%
3229531 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.62 54.0 4.19e-01 100.0% 52.9%
3302418 109.27.1.3 ↗ alpha superhelices › Repetitive alpha hairpins › BACK domain › BACK domain › NPH3 0.62 54.0 5.01e-01 100.0% 95.3%
5041259 4995.1.1.1 ↗ alpha arrays › Methionine synthase domain-like › Methionine synthase domain-like › Methionine synthase domain-like › B12-binding_2 0.61 47.0 4.50e-01 87.9% 98.8%
3594463 226.1.1.0 ↗ a+b two layers › POZ domain › POZ domain › POZ domain 0.60 50.0 3.60e-01 95.5% 40.0%
3866856 11.1.1.2 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › fn3 0.60 41.0 2.76e-01 74.2% 16.9%
3920264 109.4.1.1242 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HEAT_RRP12_N 0.59 51.0 3.42e-01 100.0% 35.4%
5017961 608.1.1.1 ↗ alpha arrays › AhpD-like › AhpD-like › AhpD-like › CMD 0.59 50.0 4.22e-01 100.0% 66.4%
5031241 192.5.1.0 ↗ alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat 0.58 49.0 4.65e-01 97.0% 95.0%
3609269 109.27.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › BACK domain › BACK domain 0.58 49.0 4.83e-01 98.5% 91.4%
3242555 101.1.1.76 ↗ alpha arrays › HTH › HTH › Three-helical HTH › Integrase_H2C2 0.56 42.0 3.49e-01 80.3% 50.8%
3305975 109.4.1.420 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR 0.55 49.0 3.90e-01 100.0% 48.9%
3989601 632.3.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Phosphoprotein XD domain › Phosphoprotein XD domain 0.55 44.0 4.58e-01 95.5% 93.3%
3598594 4995.1.1.1 ↗ alpha arrays › Methionine synthase domain-like › Methionine synthase domain-like › Methionine synthase domain-like › B12-binding_2 0.54 45.0 3.88e-01 100.0% 73.0%
3622015 101.1.1.76 ↗ alpha arrays › HTH › HTH › Three-helical HTH › Integrase_H2C2 0.50 39.0 4.08e-01 86.4% 98.3%