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S2_012_000_R2_scaffold_0_prodigal-single.1__X__X__00527
Bact-VirS2_012_000_R2_scaffold_0_prodigal-single.1__X__X__00527
Identity
- Kingdom:
- phage
Quality
80.4
mean pLDDT
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 128-186
Domain cluster:
representative
CATH (47)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3hr0B01 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.79 | 55.0 | 4.97e-01 | 72.9% | 81.0% |
| 4okvE00 | 6.10.140.1890 | Special › Helix non-globular › Helix Hairpins › | 0.77 | 53.0 | 5.18e-01 | 74.6% | 66.2% |
| 3t5vA00 | 1.25.40.990 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.75 | 52.0 | 3.26e-01 | 72.9% | 16.1% |
| 2yevC00 | 6.10.280.110 | Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.75 | 48.0 | 4.74e-01 | 72.9% | 61.9% |
| 7mwzD01 | 3.40.50.12100 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Stimulator of interferon genes protein | 0.74 | 60.0 | 4.14e-01 | 86.4% | 55.6% |
| 2w02B01 | 1.10.150.640 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › AcsD, thumb domain, helical bundle | 0.73 | 51.0 | 4.71e-01 | 76.3% | 58.1% |
| 5aj3N01 | 1.10.287.1480 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.72 | 33.0 | 2.84e-01 | 88.1% | 29.7% |
| 4abmD00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.72 | 49.0 | 4.50e-01 | 71.2% | 79.2% |
| 1ij5A01 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.72 | 52.0 | 4.76e-01 | 76.3% | 97.4% |
| 2rkhA02 | 1.20.1280.20 | Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain | 0.72 | 49.0 | 4.49e-01 | 71.2% | 57.9% |
| 2js5A00 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.72 | 50.0 | 4.69e-01 | 72.9% | 70.4% |
| 4hr1A00 | 1.20.1270.410 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.69 | 60.0 | 4.76e-01 | 96.6% | 83.9% |
| 1e7lA02 | 1.10.720.10 | Mainly Alpha › Orthogonal Bundle › Transcription Termination Factor Rho, Rna-binding Domain; Chain A, Domain 1 › | 0.69 | 45.0 | 4.70e-01 | 86.4% | 72.7% |
| 1xzzA00 | 2.80.10.50 | Mainly Beta › Trefoil › Trefoil (Acidic Fibroblast Growth Factor, subunit A) › | 0.69 | 45.0 | 3.03e-01 | 74.6% | 18.5% |
| 4q5nA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.69 | 48.0 | 3.91e-01 | 72.9% | 40.2% |
| 2yf4F00 | 1.10.3420.10 | Mainly Alpha › Orthogonal Bundle › putative ntp pyrophosphohydrolase like fold › putative ntp pyrophosphohydrolase like domain | 0.69 | 48.0 | 3.49e-01 | 71.2% | 33.6% |
| 2oznB01 | 1.20.1270.90 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › AF1782-like | 0.68 | 59.0 | 5.36e-01 | 96.6% | 95.0% |
| 2q0oC00 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.68 | 47.0 | 4.15e-01 | 74.6% | 50.0% |
| 3d36B02 | 1.10.287.130 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain | 0.68 | 47.0 | 4.70e-01 | 72.9% | 77.0% |
| 7ymiZ01 | 1.10.287.740 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Photosystem II PsbZ, reaction centre | 0.68 | 47.0 | 4.79e-01 | 72.9% | 74.1% |
| 3beyD00 | 1.20.1290.10 | Mainly Alpha › Up-down Bundle › AhpD-like › AhpD-like | 0.67 | 49.0 | 4.18e-01 | 78.0% | 51.1% |
| 2y39A00 | 1.20.120.1490 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.66 | 50.0 | 4.08e-01 | 83.1% | 84.5% |
| 4nb5B02 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.65 | 43.0 | 4.26e-01 | 71.2% | 64.1% |
| 1txuA01 | 1.10.246.120 | Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › | 0.64 | 45.0 | 3.86e-01 | 72.9% | 45.7% |
| 2y4tA02 | 1.10.287.110 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › DnaJ domain | 0.63 | 42.0 | 4.48e-01 | 71.2% | 78.8% |
| 8cdaC01 | 1.10.540.10 | Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain | 0.63 | 42.0 | 3.35e-01 | 71.2% | 34.2% |
| 3cwzB01 | 1.20.58.900 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › RUN domain | 0.62 | 44.0 | 3.34e-01 | 74.6% | 61.6% |
| 1dqeA00 | 1.10.238.20 | Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › Pheromone/general odorant binding protein domain | 0.61 | 51.0 | 3.88e-01 | 91.5% | 79.6% |
| 1hlvA02 | 1.10.10.60 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like | 0.61 | 42.0 | 4.24e-01 | 72.9% | 73.3% |
| 4gf0A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.61 | 43.0 | 3.52e-01 | 74.6% | 45.1% |
| 2rdcA00 | 1.10.287.800 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › protein ne1242 | 0.61 | 45.0 | 3.59e-01 | 83.1% | 67.7% |
| 1b5lA00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.61 | 50.0 | 3.82e-01 | 96.6% | 50.7% |
| 4m70B00 | 1.10.246.200 | Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › WPP domain | 0.61 | 53.0 | 4.63e-01 | 100.0% | 97.8% |
| 2b5dX01 | 3.20.110.10 | Alpha Beta › Alpha-Beta Barrel › 7-stranded beta/alpha barrel › Glycoside hydrolase 38, N terminal domain | 0.60 | 52.0 | 3.15e-01 | 96.6% | 73.3% |
| 2lrmA00 | 1.10.890.30 | Mainly Alpha › Orthogonal Bundle › 10k-s Protein, Hypothetical Protein A; Chain A › YmgD protein | 0.60 | 43.0 | 3.85e-01 | 84.7% | 53.6% |
| 1nv8B01 | 1.10.8.10 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain | 0.59 | 45.0 | 4.30e-01 | 84.7% | 88.7% |
| 1lvfB00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.59 | 53.0 | 4.36e-01 | 100.0% | 99.0% |
| 3axjB02 | 1.20.58.200 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 | 0.58 | 53.0 | 4.68e-01 | 100.0% | 90.6% |
| 3eabE00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.57 | 49.0 | 4.35e-01 | 96.6% | 100.0% |
| 3moiA01 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.57 | 47.0 | 3.41e-01 | 93.2% | 51.4% |
| 7p2yC03 | 1.20.150.20 | Mainly Alpha › Up-down Bundle › Lysin › ATP synthase alpha/beta chain, C-terminal domain | 0.55 | 44.0 | 3.45e-01 | 86.4% | 41.7% |
| 1x9fD00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.55 | 43.0 | 3.35e-01 | 91.5% | 37.1% |
| 3k29A00 | 1.10.287.1700 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.54 | 44.0 | 3.13e-01 | 86.4% | 46.0% |
| 4l0rB00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.54 | 43.0 | 3.94e-01 | 86.4% | 67.1% |
| 1vw4T01 | 6.10.330.20 | Special › Helix non-globular › Monooxygenase › | 0.52 | 47.0 | 3.78e-01 | 100.0% | 80.4% |
| 1hwyA01 | 1.10.287.140 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.51 | 34.0 | 3.58e-01 | 74.6% | 78.4% |
| 2o4cA03 | 3.30.1370.170 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › Erythronate-4-phosphate dehydrogenase, dimerisation domain | 0.50 | 34.0 | 3.08e-01 | 74.6% | 46.6% |
ECOD (26)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4045132 | 192.8.1.0 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain | 0.85 | 51.0 | 4.03e-01 | 74.6% | 32.7% |
| 4952853 | 5058.1.1.2 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st | 0.82 | 58.0 | 4.90e-01 | 74.6% | 48.4% |
| 3928838 | 103.4.1.0 ↗ | alpha arrays › RuvA-C › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein | 0.81 | 61.0 | 5.44e-01 | 79.7% | 63.7% |
| 3403227 | 192.8.1.465 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › CHD5 | 0.79 | 59.0 | 4.76e-01 | 79.7% | 85.5% |
| 3404270 | 377.1.1.0 ↗ | few secondary structure elements › Glucocorticoid receptor-like › LIM domain-like › LIM domain-like | 0.78 | 56.0 | 4.30e-01 | 76.3% | 36.9% |
| 4961961 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.77 | 54.0 | 4.97e-01 | 72.9% | 58.7% |
| 4283243 | 2004.1.1.149 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SecA_DEAD | 0.74 | 49.0 | 2.99e-01 | 72.9% | 11.8% |
| 3683912 | 192.7.1.0 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm | 0.72 | 50.0 | 3.94e-01 | 72.9% | 39.2% |
| 3510680 | 192.15.1.0 ↗ | alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains | 0.72 | 50.0 | 4.70e-01 | 72.9% | 75.7% |
| 4021948 | 3343.1.1.2 ↗ | alpha complex topology › gamma-tubulin complex protein 4 (GCP4) › gamma-tubulin complex protein 4 (GCP4) › gamma-tubulin complex protein 4 (GCP4) › GCP_C_terminal,GCP_N_terminal | 0.71 | 60.0 | 3.43e-01 | 100.0% | 14.7% |
| 4013672 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.70 | 53.0 | 4.39e-01 | 79.7% | 48.0% |
| 5018716 | 150.5.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like | 0.69 | 48.0 | 4.57e-01 | 72.9% | 62.9% |
| 4961031 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.69 | 47.0 | 4.50e-01 | 71.2% | 65.7% |
| 3236563 | 3567.1.1.0 ↗ | a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer | 0.69 | 44.0 | 3.36e-01 | 81.4% | 31.2% |
| 3387484 | 375.1.9.0 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Zinc-nucleated domain of serine integrase | 0.68 | 48.0 | 4.18e-01 | 76.3% | 50.6% |
| 3408508 | 3712.1.1.1 ↗ | a+b complex topology › Mediator of RNA polymerase II transcription subunit 11 › Mediator of RNA polymerase II transcription subunit 11 › Mediator of RNA polymerase II transcription subunit 11 › Med11 | 0.68 | 47.0 | 4.27e-01 | 72.9% | 55.0% |
| 4079949 | 2003.1.1.0 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains | 0.68 | 48.0 | 3.17e-01 | 76.3% | 20.0% |
| 3957419 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.68 | 47.0 | 4.34e-01 | 72.9% | 70.7% |
| 3735607 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.67 | 46.0 | 4.24e-01 | 72.9% | 55.0% |
| 3941001 | 5054.1.1.8 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 | 0.66 | 59.0 | 3.73e-01 | 98.3% | 82.7% |
| 3573589 | 632.22.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › EzrA | 0.64 | 55.0 | 4.70e-01 | 100.0% | 98.0% |
| 3619061 | 5054.1.1.8 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 | 0.63 | 55.0 | 3.65e-01 | 100.0% | 55.4% |
| 3772121 | 632.7.1.19 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › MYO6_lever | 0.63 | 50.0 | 4.53e-01 | 94.9% | 87.8% |
| 3551506 | 4177.1.1.1 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH | 0.60 | 51.0 | 3.30e-01 | 100.0% | 77.7% |
| None | — | 0.56 | 47.0 | 2.91e-01 | 94.9% | 43.7% | |
| 3622487 | 604.7.1.1 ↗ | alpha bundles › Spectrin repeat-like › Tubulin chaperone cofactor A › Tubulin chaperone cofactor A › TBCA | 0.53 | 44.0 | 3.56e-01 | 89.8% | 100.0% |
D2
medium
residues 1-64
Domain cluster:
representative
CATH (35)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1br2A03 | 1.20.120.720 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Myosin VI head, motor domain, U50 subdomain | 0.77 | 50.0 | 4.27e-01 | 71.9% | 45.3% |
| 1cxzB00 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.73 | 54.0 | 4.87e-01 | 82.8% | 58.1% |
| 1a36A04 | 1.10.132.10 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › | 0.73 | 54.0 | 3.87e-01 | 100.0% | 28.6% |
| 2wyhB04 | 1.20.1270.50 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Glycoside hydrolase family 38, central domain | 0.72 | 55.0 | 4.69e-01 | 100.0% | 51.5% |
| 4e4eA01 | 1.10.287.990 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain | 0.70 | 52.0 | 5.01e-01 | 100.0% | 70.4% |
| 1o7dC01 | 1.20.1270.50 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Glycoside hydrolase family 38, central domain | 0.69 | 52.0 | 5.29e-01 | 98.4% | 85.2% |
| 1skvA00 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.69 | 53.0 | 5.40e-01 | 98.4% | 82.8% |
| 4b6xA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.69 | 58.0 | 5.71e-01 | 98.4% | 85.5% |
| 3l9fA02 | 6.10.140.1570 | Special › Helix non-globular › Helix Hairpins › | 0.68 | 53.0 | 4.87e-01 | 92.2% | 65.4% |
| 6tqfA01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.67 | 53.0 | 3.27e-01 | 98.4% | 14.1% |
| 1hr5A00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.66 | 47.0 | 5.39e-01 | 76.6% | 100.0% |
| 4gysA02 | 1.20.58.1700 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.66 | 55.0 | 5.28e-01 | 90.6% | 100.0% |
| 3qo8A01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.66 | 59.0 | 4.96e-01 | 98.4% | 60.4% |
| 6r1nA01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.65 | 59.0 | 4.95e-01 | 98.4% | 63.1% |
| 5y06A01 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.65 | 57.0 | 3.86e-01 | 98.4% | 27.1% |
| 1wleA01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.64 | 56.0 | 4.59e-01 | 98.4% | 53.5% |
| 3favD00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.64 | 53.0 | 4.95e-01 | 89.1% | 74.4% |
| 3t6gB00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.63 | 54.0 | 4.16e-01 | 95.3% | 44.0% |
| 4aflA00 | 6.10.140.1740 | Special › Helix non-globular › Helix Hairpins › | 0.63 | 53.0 | 4.59e-01 | 95.3% | 63.7% |
| 8ctsB01 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.61 | 52.0 | 4.78e-01 | 100.0% | 100.0% |
| 1ydxA02 | 1.10.287.1120 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein | 0.60 | 53.0 | 4.76e-01 | 98.4% | 80.0% |
| 2zdiB00 | 1.10.287.370 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.60 | 54.0 | 4.55e-01 | 100.0% | 85.8% |
| 3ousA00 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.59 | 47.0 | 4.38e-01 | 87.5% | 96.3% |
| 4aciA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.58 | 46.0 | 3.42e-01 | 87.5% | 54.5% |
| 1zkeA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.58 | 51.0 | 4.74e-01 | 100.0% | 81.5% |
| 4gx0A01 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.58 | 50.0 | 4.34e-01 | 100.0% | 77.7% |
| 3dpjF00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.58 | 49.0 | 3.50e-01 | 93.8% | 37.2% |
| 2ke4A00 | 6.10.140.470 | Special › Helix non-globular › Helix Hairpins › | 0.57 | 50.0 | 4.39e-01 | 100.0% | 75.5% |
| 1ic8A01 | 1.10.260.40 | Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains | 0.57 | 46.0 | 3.98e-01 | 85.9% | 61.7% |
| 3he0B00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.54 | 44.0 | 3.22e-01 | 89.1% | 45.5% |
| 4ammA00 | 3.40.366.10 | Alpha Beta › 3-Layer(aba) Sandwich › Malonyl-Coenzyme A Acyl Carrier Protein; domain 2 › Malonyl-Coenzyme A Acyl Carrier Protein, domain 2 | 0.53 | 40.0 | 2.46e-01 | 81.2% | 71.1% |
| 1i36A02 | 1.10.1040.10 | Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 | 0.53 | 43.0 | 3.75e-01 | 90.6% | 61.6% |
| 3hzjC01 | 1.10.10.750 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Ypt/Rab-GAP domain of gyp1p, domain 1 | 0.53 | 29.0 | 3.26e-01 | 90.6% | 71.1% |
| 2kg7B00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.52 | 38.0 | 3.49e-01 | 93.8% | 56.7% |
| 4hteA02 | 1.20.58.1740 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.51 | 44.0 | 3.64e-01 | 100.0% | 53.8% |
ECOD (26)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4303085 | 3755.3.1.467 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DRC7_C | 0.79 | 60.0 | 4.77e-01 | 95.3% | 42.5% |
| 2507077 | 101.1.2.48 ↗ | alpha arrays › HTH › HTH › winged helix domain › PadR | 0.74 | 52.0 | 3.73e-01 | 84.4% | 27.0% |
| 3386973 | 5086.1.1.84 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_MFP_RND | 0.73 | 60.0 | 5.28e-01 | 95.3% | 62.2% |
| 3700089 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.72 | 54.0 | 5.40e-01 | 93.8% | 78.5% |
| 3246869 | 212.1.1.0 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like | 0.72 | 57.0 | 3.80e-01 | 95.3% | 22.9% |
| 3619435 | 192.8.1.36 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › M_domain | 0.71 | 57.0 | 4.96e-01 | 95.3% | 57.9% |
| 4927476 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.68 | 46.0 | 3.51e-01 | 70.3% | 33.1% |
| 3933048 | 4992.1.1.12 ↗ | extended segments › RelB-like › RelB-like › RelB-like › LIN9_C | 0.67 | 56.0 | 4.85e-01 | 100.0% | 59.0% |
| 5054469 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.67 | 59.0 | 4.98e-01 | 98.4% | 59.0% |
| 4120406 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.66 | 58.0 | 4.84e-01 | 98.4% | 60.9% |
| 2572867 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.65 | 59.0 | 4.83e-01 | 98.4% | 58.6% |
| 3863104 | 150.5.1.56 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › PF30874 | 0.64 | 53.0 | 4.65e-01 | 95.3% | 71.0% |
| 3279432 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.64 | 58.0 | 4.74e-01 | 98.4% | 79.1% |
| 5029495 | 3745.1.1.1 ↗ | alpha bundles › Sodium/Calcium exchanger › Sodium/Calcium exchanger › Sodium/Calcium exchanger › Na_Ca_ex | 0.63 | 50.0 | 3.26e-01 | 89.1% | 68.2% |
| 3547222 | 102.1.1.114 ↗ | alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › PF26701 | 0.63 | 50.0 | 5.14e-01 | 87.5% | 91.7% |
| 4321934 | 101.1.2.311 ↗ | alpha arrays › HTH › HTH › winged helix domain › RNA12 | 0.63 | 56.0 | 4.15e-01 | 100.0% | 73.8% |
| 3639520 | 219.1.1.9 ↗ | a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C12 | 0.62 | 53.0 | 3.40e-01 | 95.3% | 24.4% |
| 3213526 | 192.5.1.14 ↗ | alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › HR1_TOCA | 0.62 | 53.0 | 4.46e-01 | 100.0% | 57.1% |
| 3565022 | 102.1.1.0 ↗ | alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like | 0.62 | 48.0 | 4.71e-01 | 84.4% | 77.1% |
| 3808722 | 633.6.1.2 ↗ | alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › ACOX | 0.62 | 53.0 | 3.94e-01 | 96.9% | 38.1% |
| 4129922 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.61 | 53.0 | 4.62e-01 | 98.4% | 62.0% |
| 3389774 | 614.1.1.1 ↗ | alpha duplicates or obligate multimers › L27 domain › L27 domain › L27 domain › L27 | 0.61 | 42.0 | 4.53e-01 | 78.1% | 83.6% |
| 3283349 | 633.6.1.0 ↗ | alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like | 0.60 | 50.0 | 4.06e-01 | 95.3% | 92.8% |
| 3481412 | 614.1.1.1 ↗ | alpha duplicates or obligate multimers › L27 domain › L27 domain › L27 domain › L27 | 0.56 | 41.0 | 4.43e-01 | 82.8% | 90.9% |
| 3530727 | 614.1.1.1 ↗ | alpha duplicates or obligate multimers › L27 domain › L27 domain › L27 domain › L27 | 0.55 | 41.0 | 4.25e-01 | 82.8% | 86.7% |
| 3413303 | 614.1.1.1 ↗ | alpha duplicates or obligate multimers › L27 domain › L27 domain › L27 domain › L27 | 0.51 | 40.0 | 4.07e-01 | 93.8% | 93.3% |
D3
medium
residues 65-123
Domain cluster:
representative
CATH (27)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1w0bA01 | 1.20.58.420 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › AHSP | 0.84 | 61.0 | 5.24e-01 | 86.4% | 50.0% |
| 2pohA02 | 6.10.140.940 | Special › Helix non-globular › Helix Hairpins › | 0.79 | 53.0 | 4.86e-01 | 79.7% | 53.2% |
| 3g80A00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.77 | 57.0 | 5.28e-01 | 86.4% | 63.0% |
| 4h33A00 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.75 | 55.0 | 4.77e-01 | 93.2% | 50.5% |
| 7tj9A01 | 1.20.120.350 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C | 0.75 | 59.0 | 4.76e-01 | 89.8% | 46.2% |
| 4w4kA00 | 1.10.287.850 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain | 0.74 | 57.0 | 5.10e-01 | 93.2% | 59.8% |
| 3bvoA02 | 1.20.1280.20 | Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain | 0.74 | 54.0 | 4.73e-01 | 83.1% | 53.5% |
| 7jplA01 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.73 | 55.0 | 4.41e-01 | 88.1% | 41.0% |
| 3pdiA02 | 3.40.50.12380 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nitrogenase MoFe cofactor biosynthesis protein NifE, C-terminal | 0.73 | 48.0 | 3.06e-01 | 83.1% | 14.7% |
| 1dmhA00 | 2.60.130.10 | Mainly Beta › Sandwich › Protocatechuate 3,4-Dioxygenase, subunit A › Aromatic compound dioxygenase | 0.73 | 50.0 | 3.09e-01 | 71.2% | 13.6% |
| 2cwoA01 | 1.20.58.1200 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › RNA silencing suppressor P21, N-terminal domain | 0.71 | 54.0 | 5.02e-01 | 86.4% | 64.9% |
| 1s35A01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.68 | 50.0 | 4.21e-01 | 84.7% | 45.5% |
| 4gx0A01 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.68 | 56.0 | 4.73e-01 | 93.2% | 54.4% |
| 2gtsA00 | 1.10.287.850 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain | 0.67 | 55.0 | 5.09e-01 | 91.5% | 70.1% |
| 3icxA01 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.67 | 53.0 | 4.89e-01 | 89.8% | 68.0% |
| 2kp8A00 | 1.20.5.170 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.67 | 58.0 | 5.46e-01 | 98.3% | 86.1% |
| 1hqoA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.66 | 53.0 | 4.04e-01 | 86.4% | 41.2% |
| 8alzB08 | 1.10.3380.10 | Mainly Alpha › Orthogonal Bundle › Sec63 N-terminal domain-like fold › Sec63 N-terminal domain-like domain | 0.66 | 45.0 | 3.56e-01 | 83.1% | 32.8% |
| 2ckoA02 | 3.90.1200.10 | Alpha Beta › Alpha-Beta Complex › Aminoglycoside 3'-phosphotransferase; Chain: A, domain 2 › Aminoglycoside phosphotransferase (APH), C-terminal lobe | 0.66 | 52.0 | 3.43e-01 | 89.8% | 78.7% |
| 3r84B00 | 6.10.280.160 | Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Mediator of RNA polymerase II transcription subunit 22 | 0.64 | 55.0 | 4.94e-01 | 98.3% | 70.0% |
| 3ig5A04 | 1.10.8.960 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.63 | 48.0 | 4.66e-01 | 83.1% | 98.5% |
| 3eslA01 | 1.20.58.2070 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.62 | 42.0 | 3.95e-01 | 72.9% | 56.0% |
| 5hdiA00 | 1.10.630.10 | Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 | 0.62 | 52.0 | 3.23e-01 | 100.0% | 62.0% |
| 3ihmA01 | 3.50.50.60 | Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain | 0.60 | 45.0 | 3.21e-01 | 91.5% | 23.7% |
| 2lpeA01 | 6.10.140.1120 | Special › Helix non-globular › Helix Hairpins › | 0.58 | 44.0 | 4.06e-01 | 83.1% | 65.4% |
| 6qpqB00 | 1.10.10.580 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Structural maintenance of chromosome 1. Chain E | 0.55 | 38.0 | 3.46e-01 | 72.9% | 66.7% |
| 1sb7A02 | 3.30.2340.10 | Alpha Beta › 2-Layer Sandwich › Pseudouridine synthase › TruD, insertion domain | 0.55 | 47.0 | 3.58e-01 | 93.2% | 49.3% |
ECOD (25)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4951918 | 5058.1.1.0 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region | 0.85 | 63.0 | 5.28e-01 | 78.0% | 48.4% |
| 3585899 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.84 | 58.0 | 4.58e-01 | 72.9% | 38.2% |
| 5040210 | 5058.1.1.0 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region | 0.81 | 58.0 | 4.88e-01 | 81.4% | 46.3% |
| 2872910 | 5054.1.1.2 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans | 0.74 | 59.0 | 3.87e-01 | 88.1% | 21.6% |
| 4955279 | 5082.1.1.1 ↗ | alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux | 0.74 | 57.0 | 3.90e-01 | 94.9% | 24.5% |
| 3918310 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.73 | 57.0 | 4.71e-01 | 84.7% | 50.5% |
| 3485641 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.73 | 51.0 | 4.74e-01 | 83.1% | 58.7% |
| 3393765 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.72 | 63.0 | 4.23e-01 | 100.0% | 70.6% |
| 3224632 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.72 | 57.0 | 4.68e-01 | 86.4% | 50.5% |
| 3272165 | 4207.1.1.0 ↗ | alpha duplicates or obligate multimers › Mediator hinge subcomplex-like › Mediator hinge subcomplex-like › RNA polymerase II holoenzyme component SRB7 (MED21) | 0.71 | 62.0 | 5.03e-01 | 96.6% | 93.6% |
| 3493153 | 2485.1.1.49 ↗ | a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like › Thioredoxin_12 | 0.71 | 48.0 | 3.20e-01 | 78.0% | 18.2% |
| 3389713 | 174.1.1.29 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › DUF4728 | 0.71 | 60.0 | 4.53e-01 | 93.2% | 39.3% |
| 3810801 | 632.22.1.139 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › KIF21A_4th | 0.70 | 57.0 | 4.20e-01 | 93.2% | 34.7% |
| 4884100 | 5001.1.1.9 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › TAS2R | 0.70 | 60.0 | 3.91e-01 | 98.3% | 21.2% |
| 3484910 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.70 | 62.0 | 4.91e-01 | 98.3% | 51.7% |
| 5055924 | 3567.1.1.0 ↗ | a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer | 0.70 | 60.0 | 4.78e-01 | 100.0% | 54.4% |
| 4964072 | 192.29.1.309 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › DUF7547 | 0.70 | 59.0 | 5.00e-01 | 91.5% | 62.1% |
| 3600712 | 192.5.1.0 ↗ | alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat | 0.69 | 58.0 | 5.07e-01 | 91.5% | 61.2% |
| 1252173 | 4121.1.1.1 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › CorA | 0.68 | 54.0 | 3.55e-01 | 86.4% | 20.3% |
| 3269107 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.68 | 53.0 | 3.68e-01 | 86.4% | 73.7% |
| 3894879 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.68 | 53.0 | 4.43e-01 | 86.4% | 50.5% |
| 3564106 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.68 | 52.0 | 4.35e-01 | 84.7% | 49.5% |
| 3839497 | 150.5.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like | 0.68 | 56.0 | 4.95e-01 | 91.5% | 64.7% |
| 3507551 | 192.5.1.0 ↗ | alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat | 0.67 | 58.0 | 4.94e-01 | 100.0% | 60.0% |
| 3757869 | 4006.1.1.0 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain | 0.66 | 52.0 | 4.42e-01 | 84.7% | 89.5% |