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S2_012_000_R2_scaffold_0_prodigal-single.1__X__X__00669

Bact-Vir

S2_012_000_R2_scaffold_0_prodigal-single.1__X__X__00669

Identity

Kingdom:
phage

Quality

64.8 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 40-163
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF27347.1 best YeeR_C 114.3 4.40e-33 76.6% 90.3%
CATH (22)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4g6vA00 3.40.1350.120 Alpha Beta › 3-Layer(aba) Sandwich › Trna Endonuclease; Chain: A, domain 1 › 0.68 59.0 5.78e-01 95.2% 87.1%
4qbnA00 3.40.1350.10 Alpha Beta › 3-Layer(aba) Sandwich › Trna Endonuclease; Chain: A, domain 1 › 0.67 46.0 5.23e-01 92.7% 92.5%
3bm3A00 3.40.91.80 Alpha Beta › 3-Layer(aba) Sandwich › Restriction Endonuclease › 0.63 54.0 4.28e-01 93.5% 88.4%
3ndhA00 3.40.600.30 Alpha Beta › 3-Layer(aba) Sandwich › ECO RV Endonuclease; Chain A › 0.61 56.0 4.66e-01 100.0% 78.0%
3adoA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.59 50.0 4.36e-01 91.9% 74.2%
4l9yD00 3.20.20.60 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Phosphoenolpyruvate-binding domains 0.58 45.0 3.53e-01 82.3% 59.6%
1ihuA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.56 48.0 3.67e-01 94.4% 89.7%
3gwzA02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.55 48.0 3.89e-01 97.6% 74.4%
5kloA02 3.40.309.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 2 › Aldehyde Dehydrogenase; Chain A, domain 2 0.55 41.0 3.50e-01 76.6% 90.3%
4ezbA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.55 46.0 4.09e-01 91.9% 67.4%
1f2dA01 3.40.50.1100 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.54 42.0 3.54e-01 83.9% 84.9%
1pi3A01 3.40.50.970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains 0.54 44.0 3.91e-01 88.7% 78.1%
1nqkA00 3.20.20.30 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Luciferase-like domain 0.54 40.0 2.99e-01 80.6% 81.2%
3zq4A01 3.60.15.10 Alpha Beta › 4-Layer Sandwich › Metallo-beta-lactamase; Chain A › Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 0.53 42.0 3.22e-01 84.7% 84.2%
4kw2A00 3.20.20.150 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Divalent-metal-dependent TIM barrel enzymes 0.51 40.0 3.26e-01 83.1% 90.0%
5xkcA00 3.20.20.30 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Luciferase-like domain 0.51 44.0 3.00e-01 92.7% 80.9%
1nvtA02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.51 41.0 3.93e-01 86.3% 83.1%
1qzzA03 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.51 44.0 4.01e-01 96.0% 92.3%
1jpdX02 3.20.20.120 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Enolase-like C-terminal domain 0.51 40.0 3.36e-01 83.1% 77.8%
2ovlA02 3.20.20.120 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Enolase-like C-terminal domain 0.51 39.0 3.23e-01 81.5% 79.6%
2og9A02 3.20.20.120 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Enolase-like C-terminal domain 0.51 39.0 3.23e-01 83.1% 80.7%
1tvlA00 3.20.20.30 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Luciferase-like domain 0.50 41.0 2.97e-01 90.3% 87.7%
ECOD (36)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4008063 2008.1.1.197 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PF27347 0.97 75.0 8.24e-01 79.8% 100.0%
5036000 2008.1.1.165 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › RE_MjaI 0.70 43.0 5.10e-01 96.8% 90.6%
221595 2008.1.1.69 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › CdiA_C 0.68 59.0 5.78e-01 95.2% 87.1%
5040208 2008.1.1.0 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.68 55.0 5.37e-01 93.5% 78.5%
4940209 2008.1.1.0 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.68 50.0 5.74e-01 90.3% 100.0%
1349405 2008.1.1.0 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.67 46.0 5.23e-01 92.7% 92.5%
5024737 2008.1.1.0 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.67 58.0 5.31e-01 93.5% 80.0%
4031212 2008.1.1.31 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › VRR_NUC 0.67 45.0 5.19e-01 88.7% 93.3%
5057413 2008.1.1.141 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_19 0.67 53.0 5.30e-01 89.5% 81.6%
3958355 2008.1.1.0 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.65 49.0 5.38e-01 93.5% 97.0%
4928998 2008.1.1.0 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.64 58.0 5.52e-01 98.4% 89.0%
4989979 2008.1.1.0 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.64 47.0 5.03e-01 87.9% 89.5%
4978721 2008.1.1.0 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.64 55.0 5.74e-01 95.2% 100.0%
4026721 2008.1.1.0 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.63 43.0 4.71e-01 92.7% 86.0%
4934246 2008.1.1.0 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.62 52.0 5.15e-01 90.3% 85.4%
None — 0.62 55.0 4.76e-01 98.4% 70.3%
5082988 2008.2.1.1 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › tRNA-intron endonuclease catalytic domain-like › tRNA-intron endonuclease catalytic domain-like › tRNA_int_endo 0.62 46.0 5.04e-01 76.6% 98.0%
1145719 2008.1.1.62 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › ThaI 0.61 56.0 4.69e-01 100.0% 79.9%
4955243 2008.1.1.0 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.61 50.0 4.38e-01 91.9% 58.9%
5049071 2008.1.1.0 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.61 49.0 4.53e-01 86.3% 77.5%
4219781 2008.1.1.184 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › SmaI 0.60 54.0 4.35e-01 96.8% 80.4%
4936054 2008.1.1.77 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › NOV_C 0.59 49.0 5.03e-01 88.7% 100.0%
3520194 7524.1.1.1 ↗ a/b three-layered sandwiches › ALDH-like › ALDH-like › ALDH-like › Aldedh 0.57 40.0 3.87e-01 72.6% 67.1%
4264635 2003.1.5.3 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_2 0.56 48.0 3.90e-01 96.0% 75.5%
3612614 2007.1.2.28 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › Peripla_BP_A-cyclase_1 0.56 47.0 4.13e-01 91.9% 65.9%
3211514 2484.1.1.65 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Maelstrom 0.55 44.0 3.46e-01 85.5% 88.9%
3220453 2484.1.1.65 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Maelstrom 0.55 44.0 3.37e-01 85.5% 92.4%
1266312 2003.1.5.3 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_2 0.55 47.0 3.81e-01 96.0% 76.2%
3592709 2003.1.1.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains 0.54 45.0 4.09e-01 91.9% 74.9%
3318932 2003.1.5.121 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › DUF1442 0.54 38.0 3.78e-01 73.4% 70.3%
3708172 2003.1.1.42 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › NAD_binding_2 0.54 46.0 4.13e-01 96.0% 74.4%
3841567 7573.1.1.4 ↗ a/b three-layered sandwiches › PRTase-like › PRTase-like › PRTase-like › UPRTase 0.52 45.0 3.81e-01 96.0% 55.8%
4918913 7524.1.1.1 ↗ a/b three-layered sandwiches › ALDH-like › ALDH-like › ALDH-like › Aldedh 0.52 40.0 3.26e-01 82.3% 83.2%
3178773 2003.1.5.47 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › PRMT5 0.52 37.0 3.23e-01 75.8% 68.5%
4850834 2003.1.5.3 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_2 0.51 44.0 3.65e-01 93.5% 88.7%
5027195 247.1.1.12 ↗ a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B_3 0.50 40.0 3.19e-01 86.3% 90.0%
D2 medium residues 18-39_164-237
PDB
Domain cluster: representative
CATH (58)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1tf5A04 1.10.3060.10 Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA 0.76 54.0 4.37e-01 75.0% 45.1%
6t4hA03 1.10.3060.10 Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA 0.72 50.0 4.12e-01 71.9% 43.0%
2ic6A00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.72 39.0 4.48e-01 96.9% 71.8%
2oauA01 1.10.287.1260 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.72 47.0 4.67e-01 72.9% 62.7%
4tkrA00 1.10.1760.20 Mainly Alpha › Orthogonal Bundle › Arp2/3 complex 21 kDa subunit ARPC3 › 0.71 64.0 5.18e-01 100.0% 81.4%
4jndA01 1.10.1740.220 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › 0.71 37.0 3.35e-01 79.2% 37.7%
2zy9A03 1.10.357.20 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › SLC41 divalent cation transporters, integral membrane domain 0.71 63.0 5.15e-01 100.0% 54.0%
3rmiA00 1.20.59.10 Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase 0.70 53.0 5.16e-01 99.0% 72.4%
3rlbA00 1.10.1760.20 Mainly Alpha › Orthogonal Bundle › Arp2/3 complex 21 kDa subunit ARPC3 › 0.69 63.0 5.12e-01 100.0% 79.5%
1nktA04 1.10.3060.10 Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA 0.69 51.0 4.13e-01 77.1% 47.5%
5ts9B00 1.20.59.10 Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase 0.69 52.0 4.41e-01 100.0% 48.4%
5kbwB00 1.10.1760.20 Mainly Alpha › Orthogonal Bundle › Arp2/3 complex 21 kDa subunit ARPC3 › 0.68 62.0 5.10e-01 100.0% 77.8%
2khmA01 1.10.10.1350 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Spidroin domain, C-terminal domain 0.68 50.0 4.84e-01 100.0% 69.4%
1m6nA04 1.10.3060.10 Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA 0.68 50.0 4.42e-01 77.1% 54.8%
2mpnA00 6.10.140.1340 Special › Helix non-globular › Helix Hairpins › 0.66 38.0 4.41e-01 88.5% 79.4%
2mabA00 1.10.10.1350 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Spidroin domain, C-terminal domain 0.66 49.0 4.73e-01 100.0% 69.7%
7ys6A01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.66 45.0 3.31e-01 70.8% 27.3%
3zuxA00 1.20.1530.20 Mainly Alpha › Up-down Bundle › Na+/H+ antiporter like fold › 0.66 57.0 3.97e-01 94.8% 67.9%
2kw6A00 6.10.140.1300 Special › Helix non-globular › Helix Hairpins › 0.66 35.0 4.26e-01 97.9% 78.5%
3v5uA01 6.10.280.80 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › NCX, peripheral helical region 0.65 41.0 4.62e-01 92.7% 81.6%
6lumG01 1.20.1300.10 Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit 0.64 45.0 4.35e-01 83.3% 63.4%
3p5nA00 1.10.1760.20 Mainly Alpha › Orthogonal Bundle › Arp2/3 complex 21 kDa subunit ARPC3 › 0.64 53.0 4.48e-01 100.0% 53.0%
3emlA01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.64 46.0 3.33e-01 77.1% 26.4%
1w0bA01 1.20.58.420 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › AHSP 0.64 48.0 4.96e-01 99.0% 84.8%
5dvwA00 1.20.120.1160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.63 35.0 3.15e-01 91.7% 38.6%
1e7pC00 1.20.1300.10 Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit 0.62 55.0 4.03e-01 96.9% 77.6%
1zoyD00 1.20.1300.10 Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit 0.61 47.0 4.70e-01 87.5% 78.4%
8ipqB01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.61 49.0 3.57e-01 89.6% 43.4%
4fwvA02 1.20.120.1680 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.61 48.0 4.37e-01 86.5% 89.6%
1jadA00 1.20.1230.10 Mainly Alpha › Up-down Bundle › Phospholipase C Beta; Chain: A › Phospholipase C beta, distal C-terminal domain 0.61 53.0 3.93e-01 94.8% 78.9%
2wzkA03 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.61 46.0 4.41e-01 97.9% 70.0%
3ljbA00 1.20.120.1240 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Dynamin, middle domain 0.60 53.0 4.13e-01 99.0% 68.9%
3a11B01 1.20.120.420 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › translation initiation factor eif-2b, domain 1 0.60 41.0 3.79e-01 99.0% 53.6%
4kb2A01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.60 53.0 5.15e-01 100.0% 92.7%
2gs4A00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.59 47.0 4.04e-01 86.5% 86.7%
4oydB00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.59 52.0 4.94e-01 100.0% 91.5%
3vkgA08 1.10.472.130 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Dynein motor, AAA2 domain, small subdomain 0.59 42.0 3.55e-01 77.1% 43.8%
2kg7B00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.58 41.0 4.12e-01 72.9% 73.2%
2x2vA00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.58 37.0 4.28e-01 72.9% 92.6%
3on4D00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.58 51.0 4.07e-01 99.0% 49.7%
1sgmA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.58 50.0 3.99e-01 94.8% 48.4%
7ae2A01 1.20.120.580 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › bsu32300-like 0.57 47.0 4.24e-01 91.7% 85.4%
4h3tA02 1.10.132.100 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › 0.57 48.0 4.31e-01 95.8% 82.3%
2wdqD00 1.20.1300.10 Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit 0.56 44.0 4.35e-01 85.4% 85.7%
1zvzA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.55 43.0 3.96e-01 83.3% 96.8%
2uuiA00 1.20.120.550 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Membrane associated eicosanoid/glutathione metabolism-like domain 0.55 39.0 3.36e-01 74.0% 46.5%
4i17A00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.54 40.0 3.11e-01 83.3% 33.5%
4x28C03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.54 42.0 3.72e-01 83.3% 71.3%
2l6xA00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.54 48.0 3.63e-01 100.0% 97.9%
4iu9B01 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.53 47.0 3.62e-01 100.0% 68.3%
1s3qG00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.52 45.0 3.82e-01 95.8% 92.6%
3axjB01 1.20.58.190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 0.51 43.0 3.73e-01 93.8% 58.1%
2ot4A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.51 42.0 4.10e-01 99.0% 78.5%
6wk3A00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.51 45.0 3.99e-01 100.0% 91.7%
2ntxA01 1.20.58.2010 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › PRONE domain, subdomain 1 0.51 42.0 3.38e-01 94.8% 76.7%
2irmA00 3.60.40.10 Alpha Beta › 4-Layer Sandwich › Phosphatase 2c; domain 1 › PPM-type phosphatase domain 0.51 44.0 3.04e-01 96.9% 82.6%
2e9xA01 1.20.58.1030 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.50 41.0 3.71e-01 93.8% 65.6%
3agtA00 1.20.120.50 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like 0.50 42.0 3.84e-01 93.8% 70.7%
ECOD (77)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3821344 5076.1.1.1 ↗ alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier › Mito_carr 0.83 59.0 3.99e-01 72.9% 30.5%
3334228 5076.1.1.1 ↗ alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier › Mito_carr 0.83 58.0 4.03e-01 71.9% 37.1%
5040955 5058.1.1.2 ↗ alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st 0.76 53.0 5.13e-01 74.0% 64.8%
5042298 5079.1.1.1 ↗ alpha duplicates or obligate multimers › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › MgtE 0.75 68.0 5.50e-01 100.0% 55.6%
3398929 5041.1.1.32 ↗ extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › TMEM141 0.75 56.0 5.78e-01 77.1% 84.4%
3847027 5076.1.1.1 ↗ alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier › Mito_carr 0.74 51.0 3.55e-01 70.8% 33.2%
4597483 5058.1.1.1 ↗ alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1,MS_channel_1st 0.73 49.0 4.55e-01 72.9% 55.0%
4983511 7064.1.1.1 ↗ alpha bundles › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › VIT1 0.73 64.0 5.47e-01 100.0% 61.3%
3453796 7519.1.1.11 ↗ a/b three-layered sandwiches › ATP synthase (F1-ATPase), gamma subunit › ATP synthase (F1-ATPase), gamma subunit › ATP synthase (F1-ATPase), gamma subunit › Rick_17kDa_Anti, PF29034 0.73 53.0 5.17e-01 76.0% 69.5%
4012810 5058.1.1.0 ↗ alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.72 44.0 4.70e-01 84.4% 69.4%
4981035 5058.1.1.16 ↗ alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 0.71 47.0 5.48e-01 78.1% 98.5%
2566193 5058.1.1.1 ↗ alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1,MS_channel_1st 0.71 48.0 4.58e-01 72.9% 59.8%
4971237 5058.1.1.0 ↗ alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.70 47.0 4.52e-01 74.0% 60.0%
4472632 604.12.1.3 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › Thia_YuaJ 0.70 63.0 5.01e-01 100.0% 77.4%
5029408 7064.1.1.1 ↗ alpha bundles › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › VIT1 0.70 58.0 5.00e-01 100.0% 57.3%
3966348 5058.1.1.16 ↗ alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 0.70 46.0 4.87e-01 78.1% 75.3%
4389613 161.1.1.1 ↗ alpha complex topology › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA › SecA_SW 0.70 51.0 4.00e-01 77.1% 39.0%
5012687 5058.1.1.16 ↗ alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 0.69 49.0 4.96e-01 74.0% 76.8%
4937043 7516.1.1.2 ↗ a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2 0.69 58.0 3.84e-01 88.5% 45.6%
4979243 1075.1.1.0 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain 0.69 63.0 4.69e-01 100.0% 41.7%
5014612 7064.1.1.1 ↗ alpha bundles › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › VIT1 0.69 56.0 4.75e-01 99.0% 53.5%
5034026 5058.1.1.16 ↗ alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 0.69 50.0 4.92e-01 77.1% 74.3%
4218048 3236.1.1.1 ↗ alpha complex topology › Cation-proton antiporter › Cation-proton antiporter (CPA) › Cation-proton antiporter (CPA) › Na_H_Exchanger 0.68 48.0 3.45e-01 72.9% 27.2%
3810884 621.1.1.3 ↗ alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Sey1_3HB 0.68 54.0 4.66e-01 83.3% 73.1%
4317794 5058.1.1.1 ↗ alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1,MS_channel_1st 0.68 46.0 4.53e-01 72.9% 63.8%
4964132 5058.1.1.0 ↗ alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.68 49.0 4.79e-01 77.1% 68.6%
4424436 604.39.1.6 ↗ alpha bundles › Spectrin repeat-like › S-component of energy-coupling factor (ECF) transporters › S-component of energy-coupling factor (ECF) transporters › QueT 0.67 61.0 5.05e-01 100.0% 78.7%
3950431 1075.1.2.0 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain 0.67 61.0 5.34e-01 100.0% 91.4%
4939889 547.1.1.1 ↗ alpha duplicates or obligate multimers › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › GlutR_dimer 0.66 46.0 4.30e-01 71.9% 63.3%
5028558 5058.1.1.2 ↗ alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st 0.66 49.0 4.89e-01 78.1% 79.0%
4973788 7064.1.1.1 ↗ alpha bundles › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › VIT1 0.66 56.0 4.92e-01 100.0% 62.8%
3705223 109.4.1.17 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Cullin 0.66 49.0 3.25e-01 100.0% 19.5%
3275619 310.2.1.0 ↗ a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.65 57.0 5.17e-01 100.0% 94.8%
5030487 604.39.1.0 ↗ alpha bundles › Spectrin repeat-like › S-component of energy-coupling factor (ECF) transporters › S-component of energy-coupling factor (ECF) transporters 0.65 58.0 4.53e-01 100.0% 86.2%
3246273 310.2.1.1 ↗ a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF › RRF 0.64 57.0 4.57e-01 100.0% 89.7%
3734521 5076.1.1.1 ↗ alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier › Mito_carr 0.64 47.0 3.12e-01 77.1% 33.7%
3274858 7064.1.1.1 ↗ alpha bundles › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › VIT1 0.64 56.0 4.45e-01 96.9% 64.1%
5073497 7064.1.1.1 ↗ alpha bundles › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › VIT1 0.64 58.0 4.81e-01 100.0% 71.2%
3971686 7064.1.1.1 ↗ alpha bundles › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › VIT1 0.64 52.0 4.67e-01 100.0% 62.1%
3620725 5041.1.1.17 ↗ extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › Periphilin_C 0.64 45.0 4.40e-01 72.9% 74.3%
3882597 4009.1.1.0 ↗ alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins 0.64 44.0 4.54e-01 76.0% 76.7%
4939310 5045.1.1.3 ↗ alpha bundles › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › V_ATPase_I 0.63 55.0 3.86e-01 99.0% 77.6%
3290433 5058.1.1.16 ↗ alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 0.63 40.0 4.14e-01 78.1% 67.8%
3827397 5069.1.3.0 ↗ alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits 0.63 50.0 4.71e-01 85.4% 80.9%
3416148 633.6.1.12 ↗ alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › ACOX+ACOX_C_alpha1 0.63 44.0 2.95e-01 71.9% 28.5%
3743091 5058.1.1.37 ↗ alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › PF25886 0.63 48.0 4.07e-01 81.2% 50.6%
3989506 3721.1.1.0 ↗ alpha bundles › Protein regulator of cytokinesis 1 (PRC1) dimerization domain › Protein regulator of cytokinesis 1 (PRC1) dimerization domain › Protein regulator of cytokinesis 1 (PRC1) dimerization domain 0.63 32.0 3.79e-01 82.3% 70.8%
4943027 7064.1.1.1 ↗ alpha bundles › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › VIT1 0.63 54.0 4.64e-01 100.0% 59.4%
3541370 633.6.1.2 ↗ alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › ACOX 0.63 52.0 4.05e-01 89.6% 62.9%
3721541 3291.1.1.0 ↗ alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.62 46.0 4.63e-01 78.1% 82.0%
4996484 7064.1.1.1 ↗ alpha bundles › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › VIT1 0.62 56.0 4.71e-01 99.0% 69.4%
4926879 7064.1.1.1 ↗ alpha bundles › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › VIT1 0.62 53.0 4.63e-01 100.0% 61.3%
5011858 7064.1.1.1 ↗ alpha bundles › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › VIT1 0.61 52.0 4.59e-01 100.0% 62.8%
3704777 7064.1.1.1 ↗ alpha bundles › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › VIT1 0.61 52.0 4.46e-01 100.0% 57.5%
3600868 5076.1.1.0 ↗ alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier 0.61 53.0 3.88e-01 100.0% 57.2%
4931344 3236.1.1.1 ↗ alpha complex topology › Cation-proton antiporter › Cation-proton antiporter (CPA) › Cation-proton antiporter (CPA) › Na_H_Exchanger 0.61 53.0 3.60e-01 97.9% 70.4%
3387995 3758.2.1.1 ↗ alpha bundles › Bacterial hemolysins-like › Biopolymer transport protein ExbB › Biopolymer transport protein ExbB › MotA_ExbB 0.60 54.0 4.25e-01 100.0% 73.5%
5023673 3711.1.1.0 ↗ alpha bundles › LTXXQ motif family protein › LTXXQ motif family protein › LTXXQ motif family protein 0.60 51.0 4.33e-01 93.8% 60.0%
3934569 633.6.1.12 ↗ alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › ACOX+ACOX_C_alpha1 0.59 48.0 3.22e-01 87.5% 29.9%
3961527 601.1.2.0 ↗ alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) 0.59 50.0 4.46e-01 95.8% 90.3%
4017157 150.1.1.0 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.59 47.0 4.01e-01 87.5% 82.4%
3881581 310.2.1.11 ↗ a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF › DUF4456 0.59 52.0 4.38e-01 99.0% 83.0%
3589723 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.59 52.0 4.78e-01 100.0% 80.8%
4112439 5045.1.1.1 ↗ alpha bundles › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › ATP-synt_A 0.58 46.0 3.55e-01 86.5% 48.5%
4025314 7064.1.1.1 ↗ alpha bundles › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › VIT1 0.58 52.0 4.47e-01 100.0% 94.8%
4458464 2004.1.1.5 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran 0.58 44.0 3.02e-01 82.3% 29.7%
3861711 633.10.1.41 ↗ alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like › TMD0_ABC 0.56 45.0 3.78e-01 87.5% 89.4%
3772265 150.1.1.100 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › TMD0_ABC 0.56 45.0 3.83e-01 87.5% 95.0%
3479087 5001.1.1.0 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.56 41.0 2.84e-01 77.1% 33.0%
4560524 2498.1.1.9 ↗ mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M1 0.56 51.0 3.64e-01 99.0% 42.2%
3690548 633.6.1.12 ↗ alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › ACOX+ACOX_C_alpha1 0.56 46.0 3.04e-01 89.6% 32.1%
4027540 3871.1.1.1 ↗ alpha duplicates or obligate multimers › PHIST › PHIST › PHIST › PRESAN 0.54 46.0 3.99e-01 97.9% 68.8%
4953261 5082.1.1.1 ↗ alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux 0.53 46.0 3.66e-01 99.0% 80.0%
4024385 3871.1.1.1 ↗ alpha duplicates or obligate multimers › PHIST › PHIST › PHIST › PRESAN 0.52 45.0 3.98e-01 97.9% 78.6%
4227021 5045.1.1.1 ↗ alpha bundles › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › ATP-synt_A 0.52 44.0 3.43e-01 96.9% 57.5%
3619687 604.1.1.127 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › EMC4 0.52 41.0 3.96e-01 95.8% 73.6%
3239756 192.4.1.13 ↗ alpha bundles › Long alpha-hairpin › Ribosomal protein L29 (L29p) › Ribosomal protein L29 (L29p) › Cactin_mid 0.52 42.0 3.22e-01 88.5% 67.8%
D3 medium residues 238-344_365-380
PDB
D4 medium residues 381-462
PDB