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S2_012_000_R2_scaffold_0_prodigal-single.1__X__X__00696
Bact-VirS2_012_000_R2_scaffold_0_prodigal-single.1__X__X__00696
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 173-261
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00512.32 best | HisKA | 43.8 | 2.90e-11 | 64.0% | 90.9% |
CATH (30)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4iloA00 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.88 | 75.0 | 5.37e-01 | 91.0% | 36.0% |
| 2rdcA00 | 1.10.287.800 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › protein ne1242 | 0.86 | 62.0 | 5.30e-01 | 98.9% | 49.6% |
| 4w4kA00 | 1.10.287.850 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain | 0.82 | 59.0 | 6.15e-01 | 74.2% | 80.5% |
| 3na7A00 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.82 | 69.0 | 4.96e-01 | 89.9% | 38.4% |
| 4ke2A00 | 6.10.140.1860 | Special › Helix non-globular › Helix Hairpins › | 0.81 | 70.0 | 5.26e-01 | 91.0% | 59.2% |
| 2rd0B00 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.81 | 68.0 | 5.84e-01 | 91.0% | 70.5% |
| 1a36A04 | 1.10.132.10 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › | 0.81 | 54.0 | 4.27e-01 | 74.2% | 34.9% |
| 1l8dA00 | 1.10.287.510 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.81 | 59.0 | 5.65e-01 | 76.4% | 89.3% |
| 4mtxD00 | 1.10.287.130 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain | 0.81 | 65.0 | 6.39e-01 | 85.4% | 97.9% |
| 1y1uA01 | 1.20.1050.20 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › STAT transcription factor, all-alpha domain | 0.80 | 68.0 | 5.20e-01 | 91.0% | 44.6% |
| 1wdzA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.78 | 65.0 | 4.78e-01 | 89.9% | 35.1% |
| 4ijjB00 | 1.20.120.910 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › DksA, coiled-coil domain | 0.78 | 59.0 | 5.19e-01 | 79.8% | 78.5% |
| 4aflA00 | 6.10.140.1740 | Special › Helix non-globular › Helix Hairpins › | 0.78 | 59.0 | 5.60e-01 | 78.7% | 75.5% |
| 5y06A01 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.78 | 65.0 | 4.78e-01 | 92.1% | 35.4% |
| 4h63H01 | 1.20.58.1710 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.75 | 53.0 | 5.76e-01 | 73.0% | 90.3% |
| 4dciA00 | 6.10.140.1110 | Special › Helix non-globular › Helix Hairpins › | 0.75 | 59.0 | 4.94e-01 | 83.1% | 50.3% |
| 2q0oC00 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.75 | 54.0 | 5.57e-01 | 100.0% | 79.1% |
| 4l0rB00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.75 | 52.0 | 5.64e-01 | 71.9% | 87.7% |
| 2gtsA00 | 1.10.287.850 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain | 0.74 | 53.0 | 5.65e-01 | 74.2% | 89.6% |
| 2cazC00 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.74 | 51.0 | 5.80e-01 | 75.3% | 100.0% |
| 3favD00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.73 | 52.0 | 5.52e-01 | 75.3% | 84.6% |
| 1zpyA00 | 6.10.140.1960 | Special › Helix non-globular › Helix Hairpins › | 0.72 | 47.0 | 4.67e-01 | 73.0% | 63.7% |
| 2rkhA02 | 1.20.1280.20 | Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain | 0.71 | 47.0 | 5.00e-01 | 70.8% | 78.9% |
| 3nrxA00 | 1.20.58.1520 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.70 | 49.0 | 4.37e-01 | 73.0% | 84.6% |
| 2bdeA03 | 1.20.58.1160 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.69 | 50.0 | 5.33e-01 | 98.9% | 88.3% |
| 1wa8A00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.68 | 50.0 | 4.90e-01 | 79.8% | 70.7% |
| 1ydxA02 | 1.10.287.1120 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein | 0.67 | 52.0 | 5.27e-01 | 85.4% | 82.2% |
| 2ipcA04 | 1.10.3060.10 | Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA | 0.59 | 52.0 | 3.82e-01 | 97.8% | 80.6% |
| 7sf7A01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.52 | 45.0 | 3.29e-01 | 100.0% | 91.5% |
| 1e7uA05 | 1.10.1070.11 | Mainly Alpha › Orthogonal Bundle › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, Domain 5 › Phosphatidylinositol 3-/4-kinase, catalytic domain | 0.51 | 36.0 | 2.78e-01 | 71.9% | 40.8% |
ECOD (50)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5046057 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.96 | 66.0 | 7.84e-01 | 70.8% | 96.9% |
| 3970470 | 605.1.1.174 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HAMP | 0.94 | 87.0 | 7.82e-01 | 100.0% | 74.8% |
| 5028533 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.92 | 80.0 | 6.88e-01 | 91.0% | 64.6% |
| 3980443 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.92 | 86.0 | 7.74e-01 | 100.0% | 76.5% |
| 3949328 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.90 | 85.0 | 7.78e-01 | 100.0% | 80.0% |
| 4817720 | 2004.1.1.5 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran | 0.87 | 62.0 | 4.15e-01 | 73.0% | 24.6% |
| 3264065 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.87 | 70.0 | 7.36e-01 | 83.1% | 92.5% |
| 5018636 | 605.1.1.3 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA_2 | 0.87 | 60.0 | 6.73e-01 | 76.4% | 91.4% |
| 3986220 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.85 | 79.0 | 7.21e-01 | 100.0% | 77.4% |
| 3529043 | 3922.1.1.179 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › bMERB_dom | 0.85 | 73.0 | 5.67e-01 | 91.0% | 45.0% |
| 3266118 | 603.1.1.100 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF27017 | 0.85 | 59.0 | 5.20e-01 | 83.1% | 51.2% |
| 3249830 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.84 | 65.0 | 5.75e-01 | 84.3% | 58.4% |
| 3412574 | 3291.1.1.82 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › ING | 0.82 | 70.0 | 6.11e-01 | 91.0% | 66.9% |
| 3786359 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.82 | 67.0 | 6.39e-01 | 85.4% | 78.0% |
| 3567382 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.82 | 61.0 | 5.55e-01 | 78.7% | 60.0% |
| 3849660 | 11.2.1.25 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain › PL48 | 0.82 | 70.0 | 6.10e-01 | 91.0% | 62.3% |
| 3861615 | 150.1.1.190 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › SAP130_C | 0.82 | 67.0 | 6.49e-01 | 89.9% | 78.0% |
| 3573035 | 109.4.1.3370 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PL48 | 0.81 | 69.0 | 5.91e-01 | 91.0% | 60.7% |
| 3598120 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.80 | 59.0 | 5.28e-01 | 80.9% | 56.7% |
| 3917888 | 192.7.1.0 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm | 0.80 | 69.0 | 6.25e-01 | 91.0% | 73.0% |
| 3877003 | 632.22.1.95 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › PF28341 | 0.80 | 67.0 | 5.21e-01 | 91.0% | 42.6% |
| 4572974 | 3922.1.1.79 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › SAP130_C | 0.80 | 67.0 | 6.14e-01 | 94.4% | 69.6% |
| 4018440 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.80 | 63.0 | 6.23e-01 | 84.3% | 84.2% |
| 3763454 | 5086.1.1.87 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › ING | 0.79 | 67.0 | 6.01e-01 | 91.0% | 70.0% |
| 3487203 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.79 | 59.0 | 6.01e-01 | 82.0% | 81.2% |
| 3836427 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.79 | 59.0 | 5.68e-01 | 82.0% | 70.0% |
| 222991 | 192.10.1.1 ↗ | alpha bundles › Long alpha-hairpin › DnaK suppressor protein DksA, alpha-hairpin domain › DnaK suppressor protein DksA, alpha-hairpin domain › DksA_N | 0.79 | 59.0 | 5.88e-01 | 79.8% | 76.1% |
| 3608116 | 5086.1.1.177 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › KIF9 | 0.78 | 67.0 | 5.63e-01 | 92.1% | 57.9% |
| 3231243 | 4177.1.1.10 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › GMIP-like_FCH | 0.78 | 67.0 | 4.61e-01 | 93.3% | 61.7% |
| 3239791 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.77 | 62.0 | 4.85e-01 | 94.4% | 42.2% |
| 5002748 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.77 | 54.0 | 5.78e-01 | 73.0% | 88.0% |
| 3734442 | 192.8.1.35 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › DUF6594 | 0.77 | 55.0 | 4.84e-01 | 75.3% | 51.5% |
| 4142346 | 5086.1.1.87 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › ING | 0.76 | 62.0 | 5.74e-01 | 93.3% | 70.0% |
| 3167298 | 3711.1.1.0 ↗ | alpha bundles › LTXXQ motif family protein › LTXXQ motif family protein › LTXXQ motif family protein | 0.76 | 63.0 | 5.97e-01 | 94.4% | 76.2% |
| 3564399 | 3755.3.1.282 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › Tmemb_cc2 | 0.76 | 58.0 | 5.35e-01 | 83.1% | 63.5% |
| 4025636 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.76 | 66.0 | 5.45e-01 | 95.5% | 84.8% |
| 4033954 | 5058.1.1.2 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st | 0.75 | 57.0 | 5.52e-01 | 94.4% | 71.0% |
| 4303085 | 3755.3.1.467 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DRC7_C | 0.75 | 60.0 | 5.50e-01 | 88.8% | 65.8% |
| 3284621 | 150.5.1.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › WXG100 | 0.74 | 54.0 | 5.52e-01 | 76.4% | 80.0% |
| 3916497 | 632.8.1.17 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 › Rab_eff_C | 0.74 | 58.0 | 5.22e-01 | 95.5% | 60.8% |
| 3579590 | 604.6.1.0 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain | 0.74 | 66.0 | 5.70e-01 | 100.0% | 74.3% |
| 3215342 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.69 | 53.0 | 5.21e-01 | 97.8% | 76.8% |
| 3906366 | 5057.1.1.1 ↗ | alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neur_chan_memb | 0.68 | 61.0 | 5.03e-01 | 100.0% | 77.5% |
| 3598977 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.67 | 49.0 | 5.04e-01 | 77.5% | 81.2% |
| 5033256 | 4323.1.1.0 ↗ | alpha bundles › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C | 0.66 | 57.0 | 4.74e-01 | 98.9% | 67.9% |
| 5066415 | 4323.1.1.0 ↗ | alpha bundles › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C | 0.64 | 56.0 | 4.49e-01 | 98.9% | 50.3% |
| 4030059 | 3903.1.1.0 ↗ | alpha duplicates or obligate multimers › Reticulocyte binding protein 5 › Reticulocyte binding protein 5 › Reticulocyte binding protein 5 | 0.64 | 56.0 | 4.01e-01 | 100.0% | 34.6% |
| 4971051 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.64 | 53.0 | 3.51e-01 | 89.9% | 58.0% |
| 3228061 | 1147.1.1.1 ↗ | alpha bundles › RNA polymerase II elongation factor ELL2 C-terminal domain › RNA polymerase II elongation factor ELL2 C-terminal domain › RNA polymerase II elongation factor ELL2 C-terminal domain › Occludin_ELL | 0.63 | 54.0 | 4.78e-01 | 100.0% | 64.8% |
| 3643699 | 5086.1.1.207 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › Choline_transpo | 0.61 | 55.0 | 4.19e-01 | 100.0% | 51.2% |
D2
high
residues 270-405
Domain cluster:
rep: Ig7659_scaffold_8_prodigal-single.1__X__X__00240__D301-446
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02518.32 best | HATPase_c | 63.5 | 3.40e-17 | 75.7% | 96.4% |