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S2_012_000_R2_scaffold_0_prodigal-single.1__X__X__00879
Bact-VirS2_012_000_R2_scaffold_0_prodigal-single.1__X__X__00879
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 10-96
Domain cluster:
rep: NC_020158__YP_007378970.1__HVTV1-65__00064__D54-164
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01435.25 best | Peptidase_M48 | 31.2 | 2.60e-07 | 48.3% | 17.2% |
CATH (34)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4jiuA00 | 3.30.2010.10 | Alpha Beta › 2-Layer Sandwich › Zincin-like › "Metalloproteases (""zincins""), catalytic domain" | 0.80 | 59.0 | 5.55e-01 | 83.9% | 63.8% |
| 1lmlA01 | 3.10.170.20 | Alpha Beta › Roll › Elastase; domain 1 › | 0.77 | 69.0 | 5.48e-01 | 97.7% | 90.0% |
| 3cqbB01 | 3.30.2010.10 | Alpha Beta › 2-Layer Sandwich › Zincin-like › "Metalloproteases (""zincins""), catalytic domain" | 0.75 | 65.0 | 6.41e-01 | 100.0% | 88.3% |
| 2vqxA01 | 3.10.170.10 | Alpha Beta › Roll › Elastase; domain 1 › | 0.73 | 66.0 | 5.43e-01 | 100.0% | 67.1% |
| 1gkxA01 | 3.30.565.10 | Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain | 0.70 | 49.0 | 4.00e-01 | 94.3% | 41.7% |
| 4a4aA02 | 3.30.379.10 | Alpha Beta › 2-Layer Sandwich › Chitobiase; domain 2 › Chitobiase/beta-hexosaminidase domain 2-like | 0.69 | 55.0 | 4.81e-01 | 96.6% | 57.7% |
| 4l63A00 | 3.40.390.10 | Alpha Beta › 3-Layer(aba) Sandwich › Collagenase (Catalytic Domain) › Collagenase (Catalytic Domain) | 0.69 | 60.0 | 4.34e-01 | 97.7% | 76.7% |
| 2p90A01 | 3.40.50.10900 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › PAC-like subunit | 0.66 | 56.0 | 4.23e-01 | 95.4% | 86.2% |
| 2h1jA00 | 1.10.1370.30 | Mainly Alpha › Orthogonal Bundle › Neurolysin; domain 3 › | 0.65 | 59.0 | 3.55e-01 | 100.0% | 53.3% |
| 1y8oA02 | 3.30.565.10 | Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain | 0.65 | 48.0 | 3.83e-01 | 93.1% | 40.0% |
| 3wgtA01 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.62 | 53.0 | 4.18e-01 | 97.7% | 97.0% |
| 1k9fA01 | 3.30.379.10 | Alpha Beta › 2-Layer Sandwich › Chitobiase; domain 2 › Chitobiase/beta-hexosaminidase domain 2-like | 0.62 | 54.0 | 4.83e-01 | 97.7% | 84.8% |
| 4k3bA04 | 3.10.20.310 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › membrane protein fhac | 0.62 | 35.0 | 3.74e-01 | 92.0% | 62.8% |
| 4rslA01 | 3.50.50.60 | Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain | 0.61 | 51.0 | 3.81e-01 | 93.1% | 88.1% |
| 2qj8A00 | 3.40.630.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Zn peptidases | 0.61 | 53.0 | 3.66e-01 | 98.9% | 55.7% |
| 4rxtA02 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.60 | 45.0 | 3.71e-01 | 80.5% | 91.8% |
| 1ka2A00 | 1.10.1370.30 | Mainly Alpha › Orthogonal Bundle › Neurolysin; domain 3 › | 0.58 | 52.0 | 3.23e-01 | 100.0% | 86.5% |
| 4g0mA00 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.57 | 48.0 | 4.31e-01 | 98.9% | 92.6% |
| 4k3cA01 | 3.10.20.310 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › membrane protein fhac | 0.57 | 34.0 | 3.47e-01 | 92.0% | 59.8% |
| 5k1rA01 | 3.40.640.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) | 0.57 | 43.0 | 3.18e-01 | 81.6% | 100.0% |
| 2gj8D00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.57 | 49.0 | 4.03e-01 | 100.0% | 90.7% |
| 1reqA02 | 3.40.50.280 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Cobalamin-binding domain | 0.55 | 47.0 | 3.92e-01 | 98.9% | 74.4% |
| 1neiA00 | 3.30.160.220 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › YoaG | 0.55 | 31.0 | 3.50e-01 | 97.7% | 76.7% |
| 3l6uA02 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.54 | 40.0 | 3.55e-01 | 82.8% | 93.7% |
| 4tpvA00 | 3.40.33.10 | Alpha Beta › 3-Layer(aba) Sandwich › Pathogenesis-related Protein p14a › CAP | 0.54 | 47.0 | 3.75e-01 | 98.9% | 81.9% |
| 3c18A01 | 3.30.460.10 | Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2 | 0.54 | 41.0 | 3.80e-01 | 90.8% | 62.6% |
| 3venA02 | 3.30.420.40 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain | 0.54 | 47.0 | 3.47e-01 | 96.6% | 45.2% |
| 4ebjA01 | 3.30.460.10 | Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2 | 0.53 | 44.0 | 3.87e-01 | 98.9% | 61.7% |
| 3lp5A00 | 3.40.50.1820 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain | 0.52 | 44.0 | 3.26e-01 | 96.6% | 89.6% |
| 3v46A00 | 3.40.50.11990 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › RNA polymerase II accessory factor, Cdc73 C-terminal domain | 0.52 | 44.0 | 3.75e-01 | 100.0% | 91.9% |
| 2v5oA03 | 2.70.130.10 | Mainly Beta › Distorted Sandwich › Cation-dependent Mannose-6-phosphate Receptor; Chain A › Mannose-6-phosphate receptor binding domain | 0.51 | 43.0 | 3.80e-01 | 98.9% | 90.6% |
| 6iw6A02 | 3.30.460.10 | Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2 | 0.51 | 42.0 | 3.98e-01 | 92.0% | 96.3% |
| 7w8fA01 | 3.40.50.1980 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nitrogenase molybdenum iron protein domain | 0.51 | 45.0 | 3.87e-01 | 100.0% | 80.1% |
| 2fiyA00 | 3.90.1670.10 | Alpha Beta › Alpha-Beta Complex › FdhE-like fold › FdhE-like domain | 0.50 | 44.0 | 3.11e-01 | 98.9% | 94.4% |
ECOD (76)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5010190 | 2498.1.1.10 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M48 | 0.88 | 73.0 | 5.36e-01 | 100.0% | 37.1% |
| 4966006 | 2498.1.1.163 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › DUF5781 | 0.85 | 69.0 | 4.85e-01 | 98.9% | 30.8% |
| 3959412 | 2498.1.1.10 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M48 | 0.83 | 71.0 | 6.20e-01 | 100.0% | 63.2% |
| 5019353 | 2498.1.1.10 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M48 | 0.83 | 71.0 | 5.16e-01 | 100.0% | 35.9% |
| 3959513 | 2498.1.1.10 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M48 | 0.82 | 68.0 | 5.81e-01 | 97.7% | 57.0% |
| 4969796 | 2498.1.1.0 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" | 0.80 | 60.0 | 5.70e-01 | 86.2% | 68.0% |
| 4977205 | 2498.1.1.0 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" | 0.80 | 65.0 | 4.65e-01 | 100.0% | 31.7% |
| 4945343 | 2498.1.1.10 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M48 | 0.80 | 65.0 | 4.75e-01 | 100.0% | 33.5% |
| 4046090 | 2498.1.1.10 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M48 | 0.79 | 71.0 | 4.79e-01 | 100.0% | 28.6% |
| 4965710 | 2498.1.1.0 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" | 0.78 | 65.0 | 4.23e-01 | 100.0% | 22.0% |
| 185135 | 2498.1.1.10 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M48 | 0.78 | 69.0 | 6.52e-01 | 100.0% | 81.2% |
| 4504518 | 2498.1.1.10 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M48 | 0.78 | 71.0 | 4.77e-01 | 100.0% | 28.3% |
| 3936153 | 2498.1.1.39 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › SprT-like | 0.78 | 66.0 | 5.51e-01 | 93.1% | 54.7% |
| 5061805 | 2498.1.1.0 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" | 0.77 | 62.0 | 5.75e-01 | 93.1% | 69.1% |
| 4223692 | 2498.1.1.58 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › DUF2201_N | 0.77 | 65.0 | 5.13e-01 | 93.1% | 46.5% |
| 3574082 | 2498.1.1.39 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › SprT-like | 0.77 | 62.0 | 6.17e-01 | 87.4% | 85.6% |
| 4416753 | 2498.1.1.59 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_U49 | 0.76 | 68.0 | 4.73e-01 | 96.6% | 54.3% |
| 5030912 | 2498.1.1.0 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" | 0.76 | 62.0 | 4.31e-01 | 92.0% | 27.5% |
| 3609379 | 2498.1.1.0 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" | 0.76 | 61.0 | 5.44e-01 | 86.2% | 80.8% |
| 5075700 | 2498.1.1.10 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M48 | 0.75 | 67.0 | 4.98e-01 | 100.0% | 40.5% |
| 5075577 | 2498.1.1.0 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" | 0.75 | 61.0 | 5.17e-01 | 92.0% | 53.1% |
| 5080625 | 2498.1.1.0 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" | 0.75 | 62.0 | 5.70e-01 | 100.0% | 68.7% |
| 3633665 | 2498.1.1.72 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › BSP | 0.75 | 68.0 | 4.94e-01 | 100.0% | 44.2% |
| 3242920 | 2498.1.1.39 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › SprT-like | 0.75 | 65.0 | 5.37e-01 | 94.3% | 62.0% |
| 3658648 | 2498.1.1.11 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M48,Peptidase_M48_N | 0.74 | 64.0 | 4.15e-01 | 100.0% | 21.9% |
| 5053222 | 2498.1.1.10 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M48 | 0.73 | 59.0 | 4.15e-01 | 100.0% | 27.5% |
| 5014658 | 2498.1.1.0 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" | 0.72 | 65.0 | 4.61e-01 | 100.0% | 53.1% |
| 4537352 | 2498.1.1.29 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M78 | 0.72 | 47.0 | 3.84e-01 | 79.3% | 36.3% |
| 5057982 | 2498.1.1.0 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" | 0.72 | 59.0 | 4.59e-01 | 90.8% | 44.1% |
| 3953551 | 2498.1.1.29 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M78 | 0.72 | 51.0 | 3.83e-01 | 73.6% | 37.5% |
| 5050812 | 2498.1.1.0 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" | 0.71 | 59.0 | 4.19e-01 | 89.7% | 30.6% |
| 4011118 | 2498.1.1.0 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" | 0.71 | 63.0 | 4.45e-01 | 100.0% | 42.6% |
| 3199040 | 2003.1.3.1 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › Nucleotide-binding domain › DAO | 0.70 | 62.0 | 4.08e-01 | 97.7% | 96.9% |
| 5057884 | 2498.1.1.0 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" | 0.70 | 62.0 | 5.40e-01 | 100.0% | 73.3% |
| 3693426 | 2498.1.1.0 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" | 0.70 | 63.0 | 4.72e-01 | 100.0% | 66.4% |
| 5047941 | 2498.1.1.0 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" | 0.69 | 52.0 | 3.94e-01 | 81.6% | 34.5% |
| 4299003 | 2498.1.1.103 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › SpoVR | 0.69 | 62.0 | 4.36e-01 | 98.9% | 41.9% |
| 3229470 | 2003.1.3.1 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › Nucleotide-binding domain › DAO | 0.69 | 59.0 | 3.98e-01 | 95.4% | 96.4% |
| 4414342 | 2498.4.1.0 ↗ | mixed a+b and a/b › Zincin-like › HSP90 C-terminal domain (C-terminal part of Pfam 00183) › HSP90 C-terminal domain (C-terminal part of Pfam 00183) | 0.69 | 62.0 | 5.28e-01 | 100.0% | 80.7% |
| 3213517 | 2498.1.1.0 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" | 0.68 | 61.0 | 4.49e-01 | 98.9% | 44.3% |
| 4278662 | 2498.4.1.0 ↗ | mixed a+b and a/b › Zincin-like › HSP90 C-terminal domain (C-terminal part of Pfam 00183) › HSP90 C-terminal domain (C-terminal part of Pfam 00183) | 0.68 | 60.0 | 5.54e-01 | 100.0% | 81.6% |
| 3686613 | 261.1.1.0 ↗ | a+b complex topology › Hect, E3 ligase catalytic domain › Hect, E3 ligase catalytic domain › Hect, E3 ligase catalytic domain | 0.68 | 60.0 | 5.05e-01 | 100.0% | 75.3% |
| 5000976 | 2011.1.1.10 ↗ | a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Zn-dependent exopeptidases › Zn-dependent exopeptidases › FGase | 0.67 | 58.0 | 4.34e-01 | 97.7% | 83.9% |
| 3250461 | 2003.1.3.1 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › Nucleotide-binding domain › DAO | 0.67 | 58.0 | 3.90e-01 | 95.4% | 95.5% |
| 5084062 | 2498.1.1.0 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" | 0.67 | 55.0 | 5.24e-01 | 92.0% | 77.1% |
| 2888860 | 2498.1.1.29 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M78 | 0.67 | 52.0 | 4.48e-01 | 83.9% | 54.0% |
| 3703768 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.66 | 48.0 | 3.63e-01 | 93.1% | 33.3% |
| 3855100 | 2498.1.1.4 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Reprolysin | 0.66 | 58.0 | 4.35e-01 | 100.0% | 59.1% |
| 3932550 | 2498.1.1.2 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Astacin | 0.66 | 56.0 | 4.17e-01 | 97.7% | 37.2% |
| 5046934 | 2498.1.1.0 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" | 0.66 | 57.0 | 5.00e-01 | 96.6% | 70.0% |
| 2771124 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.65 | 48.0 | 4.35e-01 | 93.1% | 57.6% |
| 5024540 | 2498.1.1.0 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" | 0.64 | 45.0 | 3.80e-01 | 88.5% | 43.4% |
| 5062752 | 2498.1.1.6 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M3 | 0.64 | 53.0 | 3.31e-01 | 92.0% | 21.6% |
| 3883874 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.64 | 48.0 | 3.53e-01 | 94.3% | 31.4% |
| 3596583 | 2003.1.2.0 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain | 0.64 | 55.0 | 3.47e-01 | 95.4% | 86.7% |
| 3939742 | 2498.1.1.2 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Astacin | 0.61 | 53.0 | 4.06e-01 | 98.9% | 87.3% |
| 5081573 | 2007.1.1.0 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Class I glutamine amidotransferase-like | 0.60 | 53.0 | 3.90e-01 | 100.0% | 93.8% |
| 3258287 | 2498.5.1.0 ↗ | mixed a+b and a/b › Zincin-like › GroEL-intermediate domain like › GroEL-intermediate domain like | 0.58 | 37.0 | 3.56e-01 | 92.0% | 56.0% |
| 3232788 | 2498.5.1.1 ↗ | mixed a+b and a/b › Zincin-like › GroEL-intermediate domain like › GroEL-intermediate domain like › Cpn60_TCP1 | 0.57 | 40.0 | 3.77e-01 | 73.6% | 64.5% |
| 4284024 | 207.1.1.224 ↗ | beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › PF29466, PF29477 | 0.57 | 37.0 | 2.54e-01 | 72.4% | 20.1% |
| 3270940 | 2004.1.1.19 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Ras | 0.57 | 50.0 | 3.95e-01 | 100.0% | 85.9% |
| 3263806 | 2004.1.1.474 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Dynamin_N, MMR_HSR1 | 0.56 | 40.0 | 2.85e-01 | 74.7% | 25.7% |
| 3488663 | 63.1.1.8 ↗ | beta barrels › Mannose 6-phosphate receptor domain › Mannose 6-phosphate receptor domain › Mannose 6-phosphate receptor domain › PRKCSH, PRKCSH_1 | 0.56 | 39.0 | 3.23e-01 | 72.4% | 73.1% |
| 4312546 | 2004.1.1.73 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MMR_HSR1 | 0.55 | 48.0 | 3.74e-01 | 100.0% | 80.5% |
| None | — | 0.55 | 45.0 | 3.06e-01 | 92.0% | 98.8% | |
| 3604437 | 2007.13.1.1 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Rossmann-like domains in magnesium chelatase catalytic subunit › Rossmann-like domains in magnesium chelatase catalytic subunit › CobN-Mg_chel | 0.55 | 45.0 | 3.22e-01 | 92.0% | 99.3% |
| 4975170 | 2007.13.1.0 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Rossmann-like domains in magnesium chelatase catalytic subunit › Rossmann-like domains in magnesium chelatase catalytic subunit | 0.54 | 47.0 | 3.40e-01 | 98.9% | 99.6% |
| 4217250 | 2003.1.5.53 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › tRNA_U5-meth_tr | 0.54 | 46.0 | 3.06e-01 | 94.3% | 99.4% |
| 4025647 | 2004.1.1.73 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MMR_HSR1 | 0.54 | 47.0 | 3.76e-01 | 100.0% | 92.9% |
| 3176188 | 109.4.1.3157 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF29173, PF29174, PF29177 | 0.53 | 38.0 | 2.48e-01 | 73.6% | 32.4% |
| 4069073 | 2007.1.2.0 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I | 0.51 | 36.0 | 3.46e-01 | 78.2% | 61.9% |
| 3711821 | 2004.1.1.132 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DLIC | 0.51 | 42.0 | 3.13e-01 | 92.0% | 86.0% |
| 3460911 | 316.1.1.36 ↗ | a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › MTPAP-like_central | 0.51 | 43.0 | 3.34e-01 | 93.1% | 56.9% |
| 5061996 | 7512.1.1.30 ↗ | a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_4 | 0.50 | 44.0 | 3.29e-01 | 100.0% | 97.4% |
| 3782755 | 109.4.1.3316 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF29173, PF29177 | 0.50 | 38.0 | 2.50e-01 | 77.0% | 35.1% |
| 3719245 | 316.1.1.36 ↗ | a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › MTPAP-like_central | 0.50 | 44.0 | 3.40e-01 | 97.7% | 55.0% |
D2
medium
residues 100-156
Domain cluster:
representative
CATH (72)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1jkvA01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.94 | 87.0 | 5.79e-01 | 100.0% | 28.9% |
| 4iloA00 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.94 | 87.0 | 5.55e-01 | 100.0% | 24.2% |
| 2ib0A01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.94 | 87.0 | 6.39e-01 | 100.0% | 42.2% |
| 4hwdD00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.93 | 83.0 | 6.96e-01 | 100.0% | 60.0% |
| 1hr5A00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.93 | 75.0 | 8.08e-01 | 91.2% | 100.0% |
| 3fseB02 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.93 | 87.0 | 6.24e-01 | 100.0% | 39.6% |
| 1lrzA03 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.93 | 82.0 | 7.98e-01 | 100.0% | 87.1% |
| 3rh3A01 | 1.20.120.930 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein PF12889, N-terminal DUF3829 | 0.93 | 85.0 | 6.31e-01 | 100.0% | 45.1% |
| 4hwhE00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.92 | 81.0 | 6.89e-01 | 100.0% | 61.4% |
| 1k04A02 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.92 | 86.0 | 6.82e-01 | 100.0% | 54.8% |
| 3na7A00 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.92 | 85.0 | 5.43e-01 | 100.0% | 24.1% |
| 2ic6A00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.92 | 85.0 | 7.82e-01 | 100.0% | 94.4% |
| 5z7qA00 | 1.20.1330.10 | Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain | 0.92 | 84.0 | 5.73e-01 | 98.2% | 93.2% |
| 8e9gK01 | 1.10.287.3510 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.92 | 78.0 | 6.56e-01 | 91.2% | 57.1% |
| 4mtxD00 | 1.10.287.130 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain | 0.91 | 84.0 | 6.94e-01 | 100.0% | 60.0% |
| 2rbdA01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.90 | 82.0 | 5.91e-01 | 100.0% | 38.0% |
| 2q1kA00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.90 | 76.0 | 7.94e-01 | 91.2% | 100.0% |
| 4wpeA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.89 | 82.0 | 5.09e-01 | 100.0% | 20.7% |
| 2lm9A00 | 1.20.58.970 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.89 | 81.0 | 6.70e-01 | 100.0% | 60.4% |
| 2crbA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.89 | 79.0 | 6.49e-01 | 100.0% | 56.7% |
| 2fcwA00 | 1.20.81.10 | Mainly Alpha › Up-down Bundle › Receptor-associated Protein › RAP domain | 0.89 | 80.0 | 6.43e-01 | 100.0% | 63.2% |
| 6k6iA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.88 | 81.0 | 5.29e-01 | 100.0% | 31.1% |
| 4a17U01 | 1.10.287.310 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.88 | 76.0 | 6.80e-01 | 100.0% | 68.8% |
| 2a26B01 | 4.10.860.10 | Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › UVR domain | 0.88 | 65.0 | 7.26e-01 | 78.9% | 100.0% |
| 1zpyA00 | 6.10.140.1960 | Special › Helix non-globular › Helix Hairpins › | 0.88 | 79.0 | 6.73e-01 | 100.0% | 62.6% |
| 4aflA00 | 6.10.140.1740 | Special › Helix non-globular › Helix Hairpins › | 0.88 | 80.0 | 6.49e-01 | 100.0% | 58.8% |
| 1x4tA01 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.87 | 78.0 | 7.78e-01 | 98.2% | 98.3% |
| 4i1mB01 | 1.20.120.1700 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.87 | 80.0 | 5.98e-01 | 100.0% | 45.7% |
| 1nt2B02 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.87 | 78.0 | 7.41e-01 | 100.0% | 89.6% |
| 2dnxA00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.87 | 74.0 | 5.62e-01 | 100.0% | 41.5% |
| 4b6xA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.86 | 78.0 | 7.30e-01 | 100.0% | 87.0% |
| 8fbnB01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.86 | 75.0 | 4.96e-01 | 98.2% | 32.9% |
| 4etrB00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.85 | 76.0 | 5.88e-01 | 100.0% | 46.7% |
| 1pd3A00 | 1.10.287.230 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.85 | 69.0 | 7.09e-01 | 89.5% | 100.0% |
| 3ez0C00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.85 | 76.0 | 5.07e-01 | 100.0% | 27.4% |
| 4iggA01 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.85 | 74.0 | 7.08e-01 | 98.2% | 100.0% |
| 8e9gJ01 | 1.20.120.1200 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › NADH-ubiquinone/plastoquinone oxidoreductase chain 6, subunit NuoJ | 0.84 | 72.0 | 5.05e-01 | 93.0% | 73.1% |
| 3swhA01 | 1.10.357.50 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › | 0.84 | 75.0 | 5.31e-01 | 100.0% | 39.4% |
| 6yz2A01 | 1.20.120.350 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C | 0.84 | 75.0 | 5.85e-01 | 100.0% | 50.0% |
| 2qf9A01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.84 | 75.0 | 5.39e-01 | 100.0% | 37.2% |
| 2e5yA02 | 1.20.5.440 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › ATP synthase delta/epsilon subunit, C-terminal domain | 0.83 | 62.0 | 6.89e-01 | 78.9% | 100.0% |
| 6humG01 | 1.20.120.1200 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › NADH-ubiquinone/plastoquinone oxidoreductase chain 6, subunit NuoJ | 0.83 | 75.0 | 5.30e-01 | 98.2% | 79.4% |
| 1f6fA00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.83 | 74.0 | 5.13e-01 | 100.0% | 31.1% |
| 2v6yA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.83 | 68.0 | 6.19e-01 | 89.5% | 68.0% |
| 4fppB01 | 1.10.287.130 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain | 0.83 | 75.0 | 6.97e-01 | 100.0% | 80.3% |
| 5ffdA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.83 | 73.0 | 5.50e-01 | 100.0% | 42.3% |
| 4h63K00 | 1.10.287.3490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.83 | 73.0 | 6.10e-01 | 100.0% | 62.2% |
| 1wp7A00 | 1.10.287.770 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like | 0.82 | 72.0 | 7.02e-01 | 100.0% | 96.9% |
| 1b3qA01 | 1.10.287.560 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Histidine kinase CheA-like, homodimeric domain | 0.82 | 69.0 | 6.80e-01 | 94.7% | 91.9% |
| 4w4kA00 | 1.10.287.850 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain | 0.82 | 70.0 | 6.20e-01 | 100.0% | 65.9% |
| 4h63H01 | 1.20.58.1710 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.82 | 72.0 | 6.71e-01 | 100.0% | 88.9% |
| 1wfdA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.81 | 67.0 | 5.74e-01 | 93.0% | 60.2% |
| 3icxA01 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.81 | 70.0 | 6.47e-01 | 100.0% | 82.7% |
| 1ydxA02 | 1.10.287.1120 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein | 0.80 | 70.0 | 6.06e-01 | 100.0% | 72.2% |
| 1j30A00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.80 | 66.0 | 4.96e-01 | 93.0% | 45.4% |
| 1vctA01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.80 | 70.0 | 5.63e-01 | 98.2% | 53.2% |
| 4e6nA02 | 6.10.140.1010 | Special › Helix non-globular › Helix Hairpins › | 0.80 | 70.0 | 6.66e-01 | 100.0% | 83.3% |
| 6srbA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.79 | 68.0 | 5.51e-01 | 96.5% | 53.2% |
| 2lw1A00 | 1.10.287.380 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Valyl-tRNA synthetase, C-terminal domain | 0.79 | 69.0 | 6.10e-01 | 100.0% | 72.9% |
| 3l1nA02 | 1.20.1280.140 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.78 | 65.0 | 5.70e-01 | 94.7% | 60.9% |
| 2e9xA01 | 1.20.58.1030 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.77 | 65.0 | 5.14e-01 | 100.0% | 46.9% |
| 1rq0A01 | 6.10.140.160 | Special › Helix non-globular › Helix Hairpins › | 0.77 | 64.0 | 5.69e-01 | 100.0% | 65.1% |
| 3txsC01 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.76 | 65.0 | 6.03e-01 | 100.0% | 100.0% |
| 2y1vA04 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.75 | 65.0 | 4.53e-01 | 98.2% | 30.3% |
| 1a36A04 | 1.10.132.10 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › | 0.72 | 60.0 | 4.37e-01 | 100.0% | 32.6% |
| 2yqyA00 | 1.20.120.450 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › dinb family like domain | 0.72 | 62.0 | 4.87e-01 | 100.0% | 76.2% |
| 1cpyA02 | 1.10.287.410 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.72 | 56.0 | 5.28e-01 | 96.5% | 70.8% |
| 4e4eA01 | 1.10.287.990 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain | 0.71 | 58.0 | 5.52e-01 | 94.7% | 100.0% |
| 5b1aC01 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.71 | 59.0 | 5.61e-01 | 98.2% | 80.9% |
| 1m56C01 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.69 | 57.0 | 5.43e-01 | 98.2% | 79.7% |
| 1v4aA01 | 1.10.4050.10 | Mainly Alpha › Orthogonal Bundle › Nucleotidyltransferase substrate binding subunit/domain fold › Glutamine synthase adenylyltransferase GlnE | 0.65 | 58.0 | 4.66e-01 | 98.2% | 74.3% |
| 1y6xA00 | 1.10.287.1080 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like | 0.64 | 50.0 | 4.46e-01 | 86.0% | 56.3% |
ECOD (89)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4490049 | 3843.1.1.6 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › MrpF_PhaF | 0.97 | 91.0 | 7.55e-01 | 98.2% | 62.2% |
| 3836427 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.96 | 91.0 | 7.27e-01 | 100.0% | 85.0% |
| 3917888 | 192.7.1.0 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm | 0.95 | 89.0 | 6.86e-01 | 100.0% | 49.6% |
| 4950709 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.95 | 89.0 | 8.49e-01 | 100.0% | 87.7% |
| 4964878 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.95 | 89.0 | 8.19e-01 | 100.0% | 81.4% |
| 3247204 | 103.1.1.0 ↗ | alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain | 0.95 | 89.0 | 8.73e-01 | 100.0% | 95.0% |
| 3776400 | 192.5.1.1 ↗ | alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › HR1 | 0.94 | 88.0 | 7.72e-01 | 100.0% | 71.2% |
| 3273862 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.94 | 88.0 | 7.24e-01 | 100.0% | 60.0% |
| 4965632 | 192.7.1.85 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › DUF4349 | 0.94 | 88.0 | 8.37e-01 | 100.0% | 87.7% |
| 3934585 | 3755.3.1.465 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › KIF21A | 0.94 | 88.0 | 6.22e-01 | 100.0% | 38.0% |
| 3660123 | 4177.1.1.5 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › Vps5 | 0.94 | 88.0 | 5.51e-01 | 100.0% | 22.8% |
| 3968516 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.94 | 88.0 | 7.88e-01 | 100.0% | 77.3% |
| 3221606 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.94 | 81.0 | 6.39e-01 | 91.2% | 82.9% |
| 2394365 | 1189.1.1.0 ↗ | alpha bundles › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor | 0.93 | 87.0 | 7.70e-01 | 100.0% | 73.1% |
| 4982123 | 150.1.1.3 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Rubrerythrin | 0.93 | 87.0 | 6.36e-01 | 100.0% | 42.2% |
| 3554931 | 375.1.1.0 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related | 0.93 | 83.0 | 8.49e-01 | 94.7% | 100.0% |
| 3215342 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.93 | 87.0 | 7.14e-01 | 100.0% | 60.0% |
| 3289740 | 605.1.1.4 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA_3 | 0.93 | 85.0 | 8.39e-01 | 98.2% | 93.3% |
| 5002349 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.93 | 87.0 | 8.26e-01 | 100.0% | 87.7% |
| 3672410 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.93 | 87.0 | 7.14e-01 | 100.0% | 60.0% |
| 4551916 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.93 | 87.0 | 6.53e-01 | 100.0% | 45.6% |
| 3284863 | 150.5.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like | 0.93 | 86.0 | 5.57e-01 | 100.0% | 25.3% |
| 3639099 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.93 | 86.0 | 4.98e-01 | 100.0% | 13.6% |
| 4463756 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.93 | 87.0 | 8.00e-01 | 100.0% | 81.4% |
| 3987659 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.93 | 86.0 | 5.60e-01 | 100.0% | 26.5% |
| 3641389 | 223.1.1.0 ↗ | a+b three layers › Profilin-like › sensor domains › sensor domains | 0.93 | 86.0 | 4.99e-01 | 100.0% | 13.7% |
| 3965830 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.93 | 86.0 | 6.96e-01 | 100.0% | 57.0% |
| 5048061 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.92 | 83.0 | 8.44e-01 | 96.5% | 100.0% |
| 3213478 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.92 | 85.0 | 7.32e-01 | 100.0% | 67.1% |
| 4179301 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.92 | 85.0 | 6.65e-01 | 100.0% | 51.8% |
| 3590755 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.92 | 85.0 | 8.37e-01 | 100.0% | 95.0% |
| 4936497 | 150.1.1.14 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › EncFtn-like | 0.92 | 84.0 | 7.18e-01 | 100.0% | 64.8% |
| 4628639 | 150.1.1.59 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Coat_F | 0.92 | 85.0 | 6.99e-01 | 100.0% | 60.0% |
| 4964136 | 3843.1.1.6 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › MrpF_PhaF | 0.92 | 85.0 | 7.32e-01 | 100.0% | 67.1% |
| 3945517 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.92 | 84.0 | 6.96e-01 | 100.0% | 60.0% |
| 5012672 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.92 | 84.0 | 7.10e-01 | 100.0% | 63.3% |
| 3985434 | 622.4.1.0 ↗ | alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related | 0.91 | 84.0 | 7.08e-01 | 100.0% | 63.3% |
| 4266510 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.91 | 84.0 | 6.73e-01 | 100.0% | 54.3% |
| 3737705 | 605.4.1.4 ↗ | alpha duplicates or obligate multimers › ROP-like › ROP protein › ROP protein › DUF202 | 0.91 | 84.0 | 6.82e-01 | 100.0% | 57.0% |
| 3490044 | 603.1.1.99 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF27021 | 0.91 | 84.0 | 6.26e-01 | 100.0% | 49.2% |
| 4174467 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.91 | 83.0 | 7.05e-01 | 100.0% | 63.3% |
| 5073085 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.91 | 83.0 | 5.83e-01 | 100.0% | 34.8% |
| 3969159 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.91 | 83.0 | 5.62e-01 | 98.2% | 30.3% |
| 3968647 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.91 | 83.0 | 7.96e-01 | 100.0% | 87.7% |
| 4974349 | 225.1.1.41 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HisKA_2 | 0.90 | 80.0 | 5.56e-01 | 96.5% | 32.4% |
| 3592927 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.90 | 83.0 | 5.88e-01 | 100.0% | 36.8% |
| 5035200 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.90 | 82.0 | 7.40e-01 | 100.0% | 76.0% |
| 4105677 | 150.1.1.59 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Coat_F | 0.90 | 82.0 | 6.93e-01 | 100.0% | 63.3% |
| 3744077 | 4177.1.1.1 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH | 0.90 | 82.0 | 5.17e-01 | 100.0% | 23.9% |
| 3802497 | 109.4.1.1350 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › STAG, SCD, HEAT_SCC3-SA, PF31007 | 0.89 | 82.0 | 4.39e-01 | 100.0% | 7.1% |
| 4784166 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.89 | 76.0 | 7.09e-01 | 100.0% | 75.7% |
| 4066758 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.89 | 81.0 | 6.63e-01 | 100.0% | 57.0% |
| 4988999 | 605.1.1.352 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › PAS | 0.89 | 81.0 | 5.26e-01 | 100.0% | 24.8% |
| 5044927 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.89 | 80.0 | 7.94e-01 | 100.0% | 95.0% |
| 4018162 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.89 | 82.0 | 6.77e-01 | 100.0% | 60.0% |
| 4950969 | 2004.1.1.87 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N | 0.89 | 81.0 | 4.65e-01 | 100.0% | 13.6% |
| 4946275 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.89 | 80.0 | 5.08e-01 | 100.0% | 21.9% |
| 4962781 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.89 | 80.0 | 7.28e-01 | 100.0% | 77.3% |
| 3982010 | 605.1.1.4 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA_3 | 0.88 | 81.0 | 6.70e-01 | 100.0% | 61.1% |
| 4960850 | 5041.1.1.0 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C | 0.88 | 80.0 | 7.87e-01 | 100.0% | 96.7% |
| 3170937 | 4177.1.1.1 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH | 0.88 | 80.0 | 5.00e-01 | 100.0% | 44.7% |
| 4032165 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.88 | 80.0 | 6.57e-01 | 100.0% | 57.0% |
| 3484910 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.88 | 79.0 | 6.12e-01 | 100.0% | 47.5% |
| 3791831 | 4177.1.1.2 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR | 0.87 | 79.0 | 5.17e-01 | 100.0% | 25.9% |
| 3477777 | 4177.1.1.12 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FAM92 | 0.87 | 78.0 | 5.07e-01 | 100.0% | 24.3% |
| 5007621 | 632.11.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like | 0.86 | 79.0 | 6.54e-01 | 100.0% | 62.1% |
| 3248488 | 4177.1.1.1 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH | 0.86 | 77.0 | 4.83e-01 | 100.0% | 20.7% |
| 3503444 | 192.8.1.0 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain | 0.85 | 75.0 | 6.46e-01 | 100.0% | 82.2% |
| 4990867 | 2498.1.1.10 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M48 | 0.84 | 76.0 | 4.79e-01 | 100.0% | 21.1% |
| 4044992 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.84 | 75.0 | 6.12e-01 | 100.0% | 54.3% |
| 3655628 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.84 | 74.0 | 4.87e-01 | 100.0% | 26.0% |
| 5064482 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.84 | 74.0 | 5.30e-01 | 100.0% | 37.0% |
| 3586382 | 601.1.2.4 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Talin_R4 | 0.84 | 74.0 | 6.16e-01 | 100.0% | 57.0% |
| 4012407 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.84 | 76.0 | 7.50e-01 | 100.0% | 95.0% |
| 3029523 | 109.3.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat | 0.84 | 74.0 | 4.68e-01 | 100.0% | 27.0% |
| 3961347 | 150.5.1.53 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › PPE | 0.83 | 74.0 | 6.48e-01 | 100.0% | 82.4% |
| 4200274 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.83 | 74.0 | 6.06e-01 | 100.0% | 54.3% |
| 5002089 | 2004.1.1.144 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD_2 | 0.83 | 73.0 | 4.54e-01 | 100.0% | 18.7% |
| 3611163 | 2004.1.1.480 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_21, AAA_29 | 0.83 | 76.0 | 4.41e-01 | 100.0% | 12.8% |
| 4798159 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.81 | 71.0 | 6.52e-01 | 100.0% | 97.4% |
| 4479516 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.81 | 73.0 | 6.00e-01 | 100.0% | 57.0% |
| 4265058 | 192.15.1.73 ↗ | alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains › GrpE | 0.80 | 66.0 | 5.21e-01 | 96.5% | 44.2% |
| 3761135 | 4.1.1.374 ↗ | beta barrels › SH3 › SH3 › SH3 › FUT8_N_cat | 0.77 | 67.0 | 5.83e-01 | 100.0% | 63.3% |
| 3855461 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.76 | 67.0 | 5.89e-01 | 100.0% | 71.8% |
| 3556027 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.75 | 67.0 | 5.88e-01 | 100.0% | 71.8% |
| 3960783 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.75 | 63.0 | 5.79e-01 | 100.0% | 72.5% |
| 3902100 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.75 | 66.0 | 5.79e-01 | 100.0% | 68.2% |
| 4030237 | 192.7.1.0 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm | 0.74 | 63.0 | 5.36e-01 | 100.0% | 57.0% |
| 3699525 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.74 | 63.0 | 5.00e-01 | 98.2% | 100.0% |
D3
medium
residues 157-241
Domain cluster:
representative
CATH (14)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2qupA00 | 1.20.120.490 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hypothetical protein TM1646-like domain | 0.67 | 38.0 | 3.36e-01 | 80.0% | 38.7% |
| 2fq4A02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.61 | 49.0 | 4.16e-01 | 92.9% | 53.3% |
| 3oxfA05 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.61 | 39.0 | 4.13e-01 | 92.9% | 73.3% |
| 4y6cA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.58 | 38.0 | 2.85e-01 | 85.9% | 26.4% |
| 1j5wA02 | 1.20.58.180 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Class II aaRS and biotin synthetases; domain 2 | 0.58 | 42.0 | 4.36e-01 | 94.1% | 84.4% |
| 2mpkA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.55 | 41.0 | 4.40e-01 | 90.6% | 90.5% |
| 1yxrA01 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.55 | 39.0 | 4.14e-01 | 89.4% | 83.8% |
| 1cqxA01 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.54 | 46.0 | 3.84e-01 | 100.0% | 54.7% |
| 2qwtA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.54 | 44.0 | 3.55e-01 | 95.3% | 45.5% |
| 3n1bA02 | 1.20.1280.130 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.53 | 41.0 | 4.02e-01 | 90.6% | 77.9% |
| 6xxvC00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.52 | 48.0 | 4.37e-01 | 100.0% | 92.8% |
| 2uv8A07 | 6.10.140.1410 | Special › Helix non-globular › Helix Hairpins › | 0.52 | 40.0 | 4.03e-01 | 84.7% | 81.2% |
| 2wzkA01 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.51 | 42.0 | 3.75e-01 | 92.9% | 63.8% |
| 3gnlB02 | 1.10.287.1890 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.50 | 37.0 | 4.07e-01 | 83.5% | 97.1% |
ECOD (29)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4497104 | 191.1.1.15 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › TetR_C_11 | 0.63 | 50.0 | 4.42e-01 | 90.6% | 60.0% |
| 3971928 | 3567.1.1.0 ↗ | a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer | 0.63 | 44.0 | 4.63e-01 | 82.4% | 81.3% |
| 5053184 | 2006.1.1.1 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase | 0.59 | 40.0 | 2.97e-01 | 71.8% | 58.7% |
| 3202558 | 610.2.1.1 ↗ | alpha arrays › ERP29 C domain-like › Helical domain of Sec23/24 › Helical domain of Sec23/24 › Sec23_helical | 0.57 | 50.0 | 4.72e-01 | 100.0% | 90.5% |
| 4419537 | 632.7.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › HSP70 | 0.56 | 37.0 | 3.53e-01 | 84.7% | 57.0% |
| 3272748 | 148.1.1.4 ↗ | alpha arrays › Histone-like › Histone-related › Histone › CBFD_NFYB_HMF | 0.56 | 42.0 | 3.64e-01 | 81.2% | 57.1% |
| 3437287 | 5086.1.1.199 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › PF31016 | 0.55 | 44.0 | 3.39e-01 | 83.5% | 41.7% |
| 3389713 | 174.1.1.29 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › DUF4728 | 0.55 | 41.0 | 3.55e-01 | 80.0% | 89.3% |
| 4572974 | 3922.1.1.79 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › SAP130_C | 0.54 | 35.0 | 3.21e-01 | 83.5% | 48.7% |
| 3732984 | 101.1.17.2 ↗ | alpha arrays › HTH › HTH › FF domain › FF | 0.54 | 39.0 | 4.06e-01 | 97.6% | 85.3% |
| 3861615 | 150.1.1.190 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › SAP130_C | 0.54 | 36.0 | 3.42e-01 | 84.7% | 57.0% |
| 4016531 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.54 | 47.0 | 3.43e-01 | 97.6% | 46.5% |
| 3708446 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.54 | 39.0 | 3.94e-01 | 96.5% | 77.6% |
| 3867165 | 3871.1.1.0 ↗ | alpha duplicates or obligate multimers › PHIST › PHIST › PHIST | 0.54 | 39.0 | 3.33e-01 | 77.6% | 47.9% |
| 3941012 | 2004.1.1.87 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N | 0.53 | 38.0 | 2.56e-01 | 76.5% | 45.9% |
| 4426593 | 563.1.1.1 ↗ | alpha bundles › ATPD N-terminal domain-like › N-terminal domain of the delta subunit of the F1F0-ATP synthase › N-terminal domain of the delta subunit of the F1F0-ATP synthase › OSCP | 0.53 | 46.0 | 3.65e-01 | 94.1% | 59.4% |
| 3586089 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.53 | 42.0 | 3.45e-01 | 87.1% | 88.2% |
| 4950656 | 601.7.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain | 0.53 | 43.0 | 3.71e-01 | 87.1% | 67.7% |
| 3928340 | 310.2.1.0 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF | 0.53 | 46.0 | 3.55e-01 | 95.3% | 88.1% |
| 3202557 | 605.1.1.124 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › Brr6_like_C_C | 0.53 | 38.0 | 3.64e-01 | 81.2% | 65.0% |
| 3492889 | 11.2.1.19 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain › DUF3657 | 0.53 | 38.0 | 2.61e-01 | 77.6% | 31.6% |
| 4934670 | 601.33.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain | 0.52 | 33.0 | 3.41e-01 | 77.6% | 67.5% |
| 3282208 | 150.5.1.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › WXG100 | 0.52 | 37.0 | 3.65e-01 | 84.7% | 68.9% |
| 5051498 | 164.1.1.1 ↗ | alpha bundles › Chorismate mutase II › Chorismate mutase II › Chorismate mutase II › CM_2 | 0.52 | 35.0 | 3.53e-01 | 88.2% | 66.7% |
| 5024220 | 601.2.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Cytochromes › Cytochromes | 0.52 | 40.0 | 3.75e-01 | 88.2% | 66.7% |
| 5065335 | 1075.1.2.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain | 0.52 | 46.0 | 3.80e-01 | 100.0% | 79.4% |
| 3404252 | 5054.1.1.0 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels | 0.51 | 37.0 | 3.17e-01 | 78.8% | 66.9% |
| 3881583 | 310.2.1.0 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF | 0.51 | 43.0 | 3.57e-01 | 100.0% | 83.5% |
| 3583810 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.50 | 42.0 | 3.67e-01 | 90.6% | 75.2% |