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S2_012_000_R2_scaffold_0_prodigal-single.1__X__X__00926

Bact-Vir

S2_012_000_R2_scaffold_0_prodigal-single.1__X__X__00926

Identity

Kingdom:
phage

Quality

84.4 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 4-82
PDB
Domain cluster: representative
CATH (31)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2odmA00 1.10.287.750 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › SO2669-like 0.66 38.0 3.81e-01 83.5% 55.7%
2gscC00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.63 47.0 4.18e-01 78.5% 90.0%
2e62A01 6.10.140.420 Special › Helix non-globular › Helix Hairpins › 0.63 33.0 3.94e-01 79.7% 76.9%
2kp7A01 1.10.150.110 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › DNA polymerase beta, N-terminal domain-like 0.60 44.0 4.56e-01 79.7% 97.3%
2ozbB01 1.10.287.4070 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.60 41.0 3.52e-01 72.2% 79.4%
3nb0B03 6.10.260.10 Special › Helix non-globular › F1FO ATP Synthase › 0.59 34.0 3.33e-01 79.7% 52.4%
4rflA02 1.20.1090.10 Mainly Alpha › Up-down Bundle › Dehydroquinate synthase-like, alpha domain › Dehydroquinate synthase-like - alpha domain 0.59 50.0 3.87e-01 100.0% 93.0%
3no4A00 3.40.50.10310 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Creatininase 0.58 53.0 3.63e-01 100.0% 83.3%
6ne6A01 1.10.400.10 Mainly Alpha › Orthogonal Bundle › GI Alpha 1, domain 2-like › GI Alpha 1, domain 2-like 0.57 47.0 4.29e-01 96.2% 73.7%
3fi9A02 3.90.110.10 Alpha Beta › Alpha-Beta Complex › L-2-Hydroxyisocaproate Dehydrogenase; Chain A, domain 2 › Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal 0.57 44.0 3.37e-01 82.3% 80.3%
4l6rA02 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.57 45.0 3.08e-01 86.1% 83.6%
2gf4A00 1.20.1270.110 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Uncharacterised protein family UPF0058 0.57 43.0 4.17e-01 96.2% 72.7%
4h33A00 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.56 42.0 4.01e-01 78.5% 76.9%
2h21A02 3.90.1420.10 Alpha Beta › Alpha-Beta Complex › set domain protein methyltransferase, domain 2 › Rubisco LSMT, substrate-binding domain 0.56 41.0 3.28e-01 97.5% 37.0%
1oahA02 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.56 47.0 3.91e-01 93.7% 71.8%
2p3yA02 1.10.3360.10 Mainly Alpha › Orthogonal Bundle › VPA0735-like fold › VPA0735-like domain 0.55 45.0 4.06e-01 93.7% 64.5%
2q9rA01 1.20.1590.10 Mainly Alpha › Up-down Bundle › YP_001051499.1 fold like › YP_001051499.1 domain like 0.54 46.0 3.57e-01 100.0% 70.3%
3bc8A03 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.53 48.0 3.97e-01 98.7% 86.2%
7kdfB01 1.10.418.60 Mainly Alpha › Orthogonal Bundle › Actin-binding Protein, T-fimbrin; domain 1 › Ncd80 complex, Nuf2 subunit 0.53 46.0 3.80e-01 97.5% 78.8%
4ab5B01 3.40.190.10 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II 0.53 41.0 3.73e-01 87.3% 84.3%
1o3uA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.53 46.0 4.02e-01 96.2% 94.2%
4kjmA02 1.20.5.420 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C 0.52 33.0 3.88e-01 77.2% 92.7%
7ahdC01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.52 42.0 3.01e-01 89.9% 45.2%
1zq9A02 1.10.8.480 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.51 38.0 3.65e-01 83.5% 100.0%
4hhyC01 1.20.142.10 Mainly Alpha › Up-down Bundle › Poly(ADP-ribose) Polymerase; domain 1 › Poly(ADP-ribose) polymerase, regulatory domain 0.51 41.0 3.46e-01 94.9% 51.9%
2bk9A00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.51 43.0 3.48e-01 92.4% 77.1%
1sj8A02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.51 40.0 3.48e-01 84.8% 98.4%
2pgsA03 1.10.3410.10 Mainly Alpha › Orthogonal Bundle › putative deoxyguanosinetriphosphate triphosphohydrolase fold › putative deoxyguanosinetriphosphate triphosphohydrolase like domain 0.51 40.0 3.78e-01 87.3% 100.0%
1orjD00 1.20.120.340 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS 0.51 43.0 3.72e-01 93.7% 77.6%
3smtA02 3.90.1420.10 Alpha Beta › Alpha-Beta Complex › set domain protein methyltransferase, domain 2 › Rubisco LSMT, substrate-binding domain 0.50 42.0 3.31e-01 97.5% 43.9%
3mcqA02 3.90.650.10 Alpha Beta › Alpha-Beta Complex › Phosphoribosyl-aminoimidazole Synthetase; Chain A, domain 2 › PurM-like C-terminal domain 0.50 40.0 3.27e-01 92.4% 62.5%
ECOD (36)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4672000 589.1.1.0 ↗ alpha arrays › Triger factor/SurA peptide-binding domain-like › Triger factor/SurA peptide-binding domain-like › Porin chaperone SurA, peptide-binding domain 0.67 46.0 3.53e-01 97.5% 32.0%
3489504 135.1.1.0 ↗ alpha arrays › Transducin (alpha subunit), insertion domain › Transducin (alpha subunit), insertion domain › Transducin (alpha subunit), insertion domain 0.67 55.0 4.74e-01 89.9% 80.0%
4929631 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.67 57.0 4.44e-01 97.5% 51.7%
4028177 102.1.3.0 ↗ alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › PAP/OAS1 substrate-binding domain 0.65 49.0 3.62e-01 81.0% 91.9%
3788536 219.1.1.3 ↗ a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › UCH 0.64 52.0 3.23e-01 88.6% 15.6%
3460838 2484.1.1.157 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DUF4371 0.63 54.0 3.66e-01 97.5% 31.1%
3239379 102.1.3.9 ↗ alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › PAP/OAS1 substrate-binding domain › DZF_C 0.62 45.0 3.97e-01 77.2% 85.2%
3870915 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.62 43.0 3.15e-01 72.2% 33.0%
3411996 5054.1.1.0 ↗ alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels 0.61 43.0 3.48e-01 73.4% 55.2%
3489734 197.1.1.0 ↗ alpha bundles › Acyl-CoA binding protein-like › Acyl-CoA binding protein-like › Acyl-CoA binding protein-like 0.60 46.0 4.61e-01 83.5% 96.2%
3249566 135.1.1.1 ↗ alpha arrays › Transducin (alpha subunit), insertion domain › Transducin (alpha subunit), insertion domain › Transducin (alpha subunit), insertion domain › G-alpha 0.60 49.0 4.29e-01 89.9% 75.0%
3732287 632.22.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.59 45.0 3.99e-01 83.5% 85.8%
4970947 606.1.1.0 ↗ alpha complex topology › Nop N-terminal domain › Nop N-terminal domain › Nop N-terminal domain 0.58 49.0 4.06e-01 96.2% 51.0%
1790171 1050.1.1.1 ↗ alpha arrays › BID domain of Bartonella effector protein (Bep) › BID domain of Bartonella effector protein (Bep) › BID domain of Bartonella effector protein (Bep) › Bep_C_terminal 0.58 40.0 3.63e-01 70.9% 86.0%
3251018 135.1.1.1 ↗ alpha arrays › Transducin (alpha subunit), insertion domain › Transducin (alpha subunit), insertion domain › Transducin (alpha subunit), insertion domain › G-alpha 0.56 47.0 4.15e-01 94.9% 65.0%
3924318 6166.1.1.0 ↗ alpha bundles › N-terminal domain of Delta(14)-sterol reductase, MaSR1 › N-terminal domain of Delta(14)-sterol reductase, MaSR1 › N-terminal domain of Delta(14)-sterol reductase, MaSR1 0.56 42.0 3.14e-01 79.7% 73.3%
5061242 5059.1.1.1 ↗ alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA 0.55 40.0 2.79e-01 78.5% 75.9%
5083380 5059.1.1.1 ↗ alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA 0.55 46.0 3.15e-01 91.1% 74.5%
3743584 135.1.1.1 ↗ alpha arrays › Transducin (alpha subunit), insertion domain › Transducin (alpha subunit), insertion domain › Transducin (alpha subunit), insertion domain › G-alpha 0.55 46.0 4.15e-01 96.2% 67.8%
3212250 135.1.1.0 ↗ alpha arrays › Transducin (alpha subunit), insertion domain › Transducin (alpha subunit), insertion domain › Transducin (alpha subunit), insertion domain 0.54 46.0 4.20e-01 96.2% 70.0%
1155488 632.2.1.1 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Bacterial immunoglobulin/albumin-binding domains › Bacterial immunoglobulin/albumin-binding domains › GA 0.54 35.0 3.93e-01 87.3% 83.9%
3600118 4044.1.1.0 ↗ alpha bundles › Helical bundle domain in prismane-like proteins › Helical bundle domain in prismane-like proteins › Helical bundle domain in prismane-like proteins 0.54 45.0 4.29e-01 91.1% 82.1%
3412191 632.1.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain 0.54 40.0 3.94e-01 81.0% 83.5%
5064406 150.1.1.0 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.54 41.0 3.64e-01 84.8% 72.5%
5010956 632.11.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like 0.54 42.0 3.97e-01 84.8% 82.1%
3282529 632.1.1.3 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain › Alpha-mann_mid 0.53 45.0 4.09e-01 91.1% 81.9%
3517280 3352.1.1.0 ↗ alpha bundles › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain 0.53 45.0 2.97e-01 97.5% 22.5%
3927684 5057.1.1.0 ↗ alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore 0.53 44.0 3.49e-01 88.6% 83.2%
5039732 604.12.1.0 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.53 37.0 3.27e-01 72.2% 70.8%
3538350 3755.1.1.0 ↗ alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related 0.52 41.0 3.42e-01 83.5% 57.0%
3258130 101.1.2.119 ↗ alpha arrays › HTH › HTH › winged helix domain › Tau95 0.52 37.0 2.95e-01 74.7% 94.5%
4095847 2004.1.1.5 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran 0.51 42.0 3.01e-01 89.9% 31.5%
3931393 632.1.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain 0.51 41.0 3.47e-01 86.1% 58.4%
4597634 632.19.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Choline binding protein A › Choline binding protein A 0.50 41.0 4.09e-01 86.1% 96.2%
4975320 2006.1.1.18 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › HAD_2 0.50 43.0 3.15e-01 94.9% 35.9%
3601385 5054.1.1.0 ↗ alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels 0.50 42.0 3.35e-01 93.7% 80.6%
D2 high residues 251-400
PDB
Domain cluster: representative
CATH (7)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2hujA00 1.20.120.440 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YppE-like 0.60 30.0 3.27e-01 92.7% 54.4%
2pv4A00 1.10.3440.10 Mainly Alpha › Orthogonal Bundle › Sama2622-like fold › Sama2622-like 0.59 31.0 3.25e-01 83.3% 53.1%
3oqvA00 3.40.50.11710 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Cyclodipeptide synthase 0.54 38.0 3.43e-01 100.0% 50.2%
2igpA00 1.10.418.30 Mainly Alpha › Orthogonal Bundle › Actin-binding Protein, T-fimbrin; domain 1 › Ncd80 complex, Ncd80 subunit 0.54 39.0 4.34e-01 93.3% 100.0%
6vvoE02 1.20.272.10 Mainly Alpha › Up-down Bundle › Zinc Finger, Delta Prime; domain 3 › 0.52 30.0 3.51e-01 91.3% 82.8%
8jpdG01 1.10.167.10 Mainly Alpha › Orthogonal Bundle › Regulator of G-protein Signalling 4; domain 2 › Regulator of G-protein Signalling 4, domain 2 0.51 37.0 3.82e-01 82.7% 77.9%
4q5qA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.51 29.0 3.47e-01 76.0% 81.9%
D3 high residues 420-502_535-564
PDB
Domain cluster: representative
CATH (18)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1dd5A01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.72 50.0 5.15e-01 76.1% 74.3%
4xpwA00 1.20.120.50 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like 0.69 40.0 3.86e-01 79.6% 49.6%
4dlqA02 1.25.40.610 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.67 39.0 4.27e-01 82.3% 68.4%
2wzkA03 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.65 44.0 4.48e-01 84.1% 70.9%
1aj3A00 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.64 43.0 4.56e-01 80.5% 78.6%
3rkgA02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.64 50.0 4.45e-01 85.8% 57.9%
7tj9A01 1.20.120.350 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C 0.63 39.0 4.03e-01 80.5% 65.1%
1sj7C00 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.60 45.0 3.91e-01 77.0% 85.5%
2gs4A00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.60 46.0 4.15e-01 81.4% 79.1%
2v0xA01 1.10.287.3160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.60 53.0 4.66e-01 98.2% 75.0%
2e9xA01 1.20.58.1030 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.59 40.0 3.89e-01 86.7% 60.9%
2fsfB04 1.10.3060.10 Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA 0.57 50.0 4.11e-01 98.2% 71.7%
4q5nA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.57 37.0 3.73e-01 84.1% 65.2%
3ajmB02 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.56 44.0 4.19e-01 83.2% 71.4%
2qqyA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.54 41.0 3.83e-01 99.1% 64.5%
1b5lA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.53 41.0 3.75e-01 100.0% 60.5%
3agrA01 3.30.420.530 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › 0.52 39.0 3.10e-01 78.8% 64.8%
1u61A00 1.10.1520.10 Mainly Alpha › Orthogonal Bundle › Ribonuclease iii, N-terminal Endonuclease Domain; Chain A › Ribonuclease III domain 0.51 39.0 3.79e-01 86.7% 71.7%
ECOD (30)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3427778 604.1.1.144 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › PF26575 0.75 46.0 5.36e-01 84.1% 86.3%
3252760 310.2.1.0 ↗ a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.74 52.0 5.19e-01 80.5% 71.1%
5019542 622.4.1.67 ↗ alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related › DUF5518 0.73 47.0 5.01e-01 77.0% 74.7%
4474640 604.1.1.150 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › PF28954 0.73 56.0 5.41e-01 80.5% 77.6%
4986745 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.70 46.0 4.03e-01 87.6% 45.0%
5058842 604.5.1.0 ↗ alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) 0.68 43.0 4.80e-01 82.3% 80.0%
5044572 310.2.1.0 ↗ a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.68 47.0 4.92e-01 77.0% 76.2%
3931480 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.68 39.0 4.37e-01 82.3% 71.1%
3231223 5054.1.1.0 ↗ alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels 0.67 56.0 4.83e-01 91.2% 67.2%
5007869 601.33.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain 0.67 39.0 4.18e-01 77.0% 66.0%
3404501 706.1.1.2 ↗ beta complex topology › Head domain of nucleotide exchange factor GrpE › Head domain of nucleotide exchange factor GrpE › Head domain of nucleotide exchange factor GrpE › MIEAP 0.66 54.0 4.49e-01 87.6% 76.9%
4520789 1204.1.1.0 ↗ alpha bundles › Bacteriocin pyocin-S2 N-terminal domain › Bacteriocin pyocin-S2 N-terminal domain › Bacteriocin pyocin-S2 N-terminal domain 0.65 53.0 4.33e-01 87.6% 55.2%
4018180 4121.1.1.0 ↗ a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like 0.64 58.0 4.42e-01 98.2% 52.2%
3616669 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.64 49.0 4.94e-01 84.1% 79.1%
3332592 5069.1.1.62 ↗ alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Chloroplast_duf 0.64 40.0 4.09e-01 82.3% 64.5%
3472115 310.2.1.0 ↗ a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.64 48.0 4.69e-01 79.6% 78.4%
3238347 3567.1.1.0 ↗ a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer 0.63 53.0 4.15e-01 94.7% 64.7%
3582242 1075.5.1.5 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Rft-1 0.61 48.0 3.60e-01 84.1% 67.9%
3238213 604.12.1.0 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.60 47.0 4.75e-01 82.3% 82.7%
4169938 3684.1.1.44 ↗ alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › DAHL 0.60 38.0 3.83e-01 81.4% 61.7%
3459347 1075.5.1.1 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE 0.60 46.0 3.90e-01 79.6% 80.6%
3248743 3277.2.1.1 ↗ alpha arrays › Thymine dioxygenase JBP1 DNA-binding domain-like › a C-terminal domain in chromodomain helicase DNA-binding protein 1 › a C-terminal domain in chromodomain helicase DNA-binding protein 1 › CHD1-like_C 0.60 39.0 4.27e-01 77.0% 78.9%
None — 0.60 47.0 3.97e-01 85.0% 68.7%
3979628 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.59 46.0 4.12e-01 82.3% 60.6%
3673192 192.29.1.0 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.58 43.0 3.76e-01 80.5% 51.8%
4963154 3236.1.1.1 ↗ alpha complex topology › Cation-proton antiporter › Cation-proton antiporter (CPA) › Cation-proton antiporter (CPA) › Na_H_Exchanger 0.57 47.0 3.22e-01 90.3% 42.2%
3511084 3922.1.1.225 ↗ alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › DUF842 0.54 43.0 4.21e-01 85.0% 92.0%
3406162 4006.1.1.13 ↗ alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › DUF842 0.53 43.0 4.19e-01 85.8% 81.6%
4026971 4323.1.1.2 ↗ alpha bundles › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › V-ATPase_C 0.52 48.0 4.35e-01 100.0% 86.0%
4501780 310.2.1.5 ↗ a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF › DUF842 0.51 42.0 4.07e-01 86.7% 90.4%
D4 medium residues 88-163
PDB
Domain cluster: representative
CATH (61)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3eslA01 1.20.58.2070 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.79 51.0 5.17e-01 93.4% 66.7%
2r9iA00 1.10.287.80 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain 0.74 55.0 5.74e-01 98.7% 84.5%
4ioeA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.74 53.0 5.14e-01 100.0% 66.7%
2lmgA00 1.20.1270.10 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.73 47.0 4.81e-01 85.5% 67.6%
2uubT00 1.20.58.110 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Ribosomal protein S20 0.73 53.0 4.84e-01 90.8% 58.6%
2efkA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.72 59.0 4.00e-01 100.0% 25.6%
1ykhA00 6.10.140.200 Special › Helix non-globular › Helix Hairpins › 0.69 53.0 4.96e-01 100.0% 66.3%
2ic6A00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.69 59.0 6.12e-01 98.7% 100.0%
2b6cA02 1.25.40.290 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › ARM repeat domains 0.68 36.0 3.30e-01 82.9% 38.1%
6v3zA00 1.20.141.10 Mainly Alpha › Up-down Bundle › Chitosanase, subunit A; domain 1 › Chitosanase, subunit A, domain 1 0.68 49.0 3.70e-01 75.0% 40.4%
3fd9A03 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.68 57.0 5.80e-01 100.0% 95.9%
6whbA01 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.67 45.0 3.09e-01 100.0% 19.1%
3t98B00 6.10.140.1350 Special › Helix non-globular › Helix Hairpins › 0.67 59.0 5.66e-01 98.7% 84.9%
1nt2B02 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.67 53.0 5.60e-01 98.7% 98.5%
3cazB00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.66 58.0 4.13e-01 98.7% 34.3%
3sjqC00 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.66 49.0 4.89e-01 100.0% 77.5%
3nvoB02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.65 59.0 5.12e-01 100.0% 66.4%
4m0mA03 1.20.1270.430 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.65 41.0 4.08e-01 86.8% 60.8%
4abmD00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.64 57.0 5.68e-01 100.0% 96.1%
6grjB01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.64 54.0 3.56e-01 93.4% 65.7%
3r84B00 6.10.280.160 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Mediator of RNA polymerase II transcription subunit 22 0.63 55.0 5.47e-01 94.7% 92.5%
1k04A02 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.63 55.0 4.93e-01 94.7% 70.2%
2xokP00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.63 49.0 5.01e-01 97.4% 86.5%
4lwsB00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.63 54.0 5.20e-01 97.4% 83.0%
3na7A00 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.63 56.0 3.92e-01 98.7% 32.9%
3cqxC00 1.20.58.890 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.62 52.0 5.10e-01 93.4% 84.0%
3ofnY00 1.10.287.80 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain 0.62 56.0 4.85e-01 100.0% 86.1%
1br0A00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.62 55.0 4.77e-01 100.0% 75.0%
4dciA00 6.10.140.1110 Special › Helix non-globular › Helix Hairpins › 0.62 54.0 4.37e-01 97.4% 55.1%
1x3kA01 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.62 41.0 3.32e-01 93.4% 35.4%
1i6zA00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.61 53.0 4.43e-01 97.4% 56.3%
3favD00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.61 52.0 5.24e-01 98.7% 91.0%
3r84A00 1.10.287.3490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.61 54.0 5.33e-01 100.0% 97.5%
3ibpA01 1.20.58.850 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.61 51.0 5.23e-01 92.1% 95.8%
1gt0D00 1.10.30.10 Mainly Alpha › Orthogonal Bundle › DNA Binding (I), subunit A › High mobility group box domain 0.61 47.0 4.65e-01 82.9% 84.8%
6v9zA02 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.61 53.0 3.51e-01 98.7% 35.1%
1ydxA02 1.10.287.1120 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein 0.60 53.0 5.03e-01 98.7% 86.7%
4w4kA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.60 53.0 5.23e-01 100.0% 92.7%
3tbiB02 6.10.140.1670 Special › Helix non-globular › Helix Hairpins › 0.60 52.0 4.79e-01 97.4% 85.0%
4py6C00 1.20.920.10 Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like 0.60 52.0 4.42e-01 98.7% 93.7%
7b00A01 1.20.1740.10 Mainly Alpha › Up-down Bundle › Amino acid/polyamine transporter I › Amino acid/polyamine transporter I 0.60 49.0 3.03e-01 100.0% 15.2%
1u3dA02 1.25.40.80 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.59 40.0 3.45e-01 92.1% 40.3%
2vs0A00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.59 53.0 5.17e-01 100.0% 97.6%
3lszA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.59 50.0 4.29e-01 100.0% 58.4%
4dxwA02 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.59 51.0 4.52e-01 97.4% 82.1%
2vf8B02 1.20.1580.10 Mainly Alpha › Up-down Bundle › ABC transporter ATPase like fold › ABC transporter ATPase like domain 0.58 51.0 4.03e-01 98.7% 99.4%
3zbhA00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.58 51.0 4.90e-01 100.0% 88.9%
3g9gA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.58 51.0 3.59e-01 100.0% 44.4%
1otkA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.58 49.0 3.56e-01 100.0% 75.0%
4v1gA00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.58 44.0 4.33e-01 98.7% 76.5%
8ek4A01 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.58 51.0 4.21e-01 97.4% 73.7%
2x2vA00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.57 46.0 4.80e-01 96.1% 100.0%
6ynwH01 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.57 45.0 4.56e-01 98.7% 89.2%
1qrvA00 1.10.30.10 Mainly Alpha › Orthogonal Bundle › DNA Binding (I), subunit A › High mobility group box domain 0.57 46.0 4.71e-01 90.8% 94.5%
2vf7B01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.57 51.0 3.33e-01 100.0% 46.0%
2rdcA00 1.10.287.800 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › protein ne1242 0.55 46.0 3.90e-01 96.1% 63.9%
2fzlA02 6.10.140.1180 Special › Helix non-globular › Helix Hairpins › 0.55 41.0 4.39e-01 85.5% 98.4%
2nsfA01 1.20.120.450 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › dinb family like domain 0.54 46.0 3.68e-01 98.7% 68.6%
4lwsA00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.53 45.0 4.21e-01 97.4% 75.0%
1jadA00 1.20.1230.10 Mainly Alpha › Up-down Bundle › Phospholipase C Beta; Chain: A › Phospholipase C beta, distal C-terminal domain 0.52 45.0 3.17e-01 96.1% 30.6%
5zr4A01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.52 40.0 3.60e-01 81.6% 59.8%
ECOD (58)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5036728 632.22.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.77 49.0 5.08e-01 89.5% 70.0%
3847053 192.15.1.0 ↗ alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains 0.71 53.0 5.36e-01 100.0% 80.0%
3182561 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.67 52.0 4.06e-01 100.0% 38.8%
3654060 3722.1.1.1 ↗ alpha bundles › Protein regulator of cytokinesis 1 (PRC1) rod domain › Protein regulator of cytokinesis 1 (PRC1) rod domain › Protein regulator of cytokinesis 1 (PRC1) rod domain › MAP65_ASE1 0.67 46.0 3.30e-01 92.1% 24.0%
3770066 3291.1.1.169 ↗ alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › KIF21A_4th 0.66 61.0 4.41e-01 100.0% 45.6%
3908132 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.65 59.0 4.02e-01 98.7% 29.5%
3913300 3755.3.1.303 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › KIF21A_4th 0.65 59.0 4.68e-01 100.0% 51.3%
3562849 148.1.3.254 ↗ alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › KIF21A_4th 0.64 59.0 4.12e-01 100.0% 33.5%
3939746 4177.1.1.0 ↗ alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.64 57.0 4.35e-01 98.7% 45.7%
4018084 605.1.1.0 ↗ alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.64 53.0 5.52e-01 89.5% 100.0%
3639878 5086.1.1.0 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.64 53.0 4.94e-01 90.8% 74.7%
3200117 4207.1.1.0 ↗ alpha duplicates or obligate multimers › Mediator hinge subcomplex-like › Mediator hinge subcomplex-like › RNA polymerase II holoenzyme component SRB7 (MED21) 0.64 55.0 4.42e-01 93.4% 50.7%
4957689 5069.1.1.0 ↗ alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes 0.64 51.0 4.27e-01 100.0% 50.8%
3471023 164.1.1.15 ↗ alpha bundles › Chorismate mutase II › Chorismate mutase II › Chorismate mutase II › PPPI_inhib 0.64 57.0 4.43e-01 98.7% 47.5%
3223457 101.1.2.661 ↗ alpha arrays › HTH › HTH › winged helix domain › HTH_9, POLR3C_WHD 0.64 57.0 3.84e-01 100.0% 36.8%
4012743 192.29.1.0 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.63 55.0 4.23e-01 100.0% 95.0%
4026286 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.63 56.0 4.63e-01 98.7% 80.0%
3792423 4207.1.1.38 ↗ alpha duplicates or obligate multimers › Mediator hinge subcomplex-like › Mediator hinge subcomplex-like › RNA polymerase II holoenzyme component SRB7 (MED21) › PF30341 0.63 54.0 4.47e-01 92.1% 53.8%
1693762 633.6.1.1 ↗ alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA_dh_1 0.63 56.0 4.42e-01 98.7% 49.0%
3987991 5086.1.1.94 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HB_LcnD 0.63 56.0 4.05e-01 98.7% 100.0%
3488191 605.1.1.0 ↗ alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.63 53.0 4.98e-01 93.4% 76.8%
4968655 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.63 56.0 4.44e-01 100.0% 50.3%
3458695 605.1.1.0 ↗ alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.63 50.0 5.24e-01 86.8% 97.1%
3623411 192.2.1.0 ↗ alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.62 56.0 5.19e-01 100.0% 100.0%
4324499 3755.1.1.3 ↗ alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related › SPAM 0.62 56.0 4.52e-01 100.0% 69.0%
3775225 3755.1.1.6 ↗ alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related › USHBP1_PDZ-bd 0.62 56.0 4.32e-01 100.0% 47.3%
4092397 109.4.1.1448 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_1, TPR_7, TPR_10, TPR_12, TPR_MalT 0.62 55.0 3.36e-01 98.7% 16.6%
4946656 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.62 54.0 4.68e-01 98.7% 75.8%
3493493 632.8.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 0.62 55.0 4.89e-01 100.0% 70.9%
3940778 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.61 54.0 4.64e-01 100.0% 63.2%
4236657 633.21.1.18 ↗ alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › CASP_dom 0.61 53.0 4.26e-01 98.7% 49.7%
4016292 192.2.1.18 ↗ alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › ING 0.61 55.0 4.53e-01 100.0% 57.8%
4287748 603.1.1.128 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins › MSP1_C 0.61 54.0 3.79e-01 100.0% 46.7%
3661867 192.15.1.0 ↗ alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains 0.60 50.0 4.55e-01 90.8% 69.0%
3167394 874.1.1.0 ↗ a+b duplicates or obligate multimers › Smc hinge domain › Smc hinge domain › Smc hinge domain 0.60 53.0 3.67e-01 100.0% 61.9%
3762580 190.1.1.1 ↗ alpha arrays › HMG-box-like › HMG-box › HMG-box › HMG_box 0.60 49.0 4.91e-01 93.4% 88.7%
3628093 604.3.1.0 ↗ alpha bundles › Spectrin repeat-like › BAG domain › BAG domain 0.59 53.0 4.76e-01 100.0% 74.3%
4217794 5086.1.1.94 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HB_LcnD 0.59 52.0 4.46e-01 100.0% 96.8%
3714267 1075.4.1.2 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane_2 0.59 52.0 3.37e-01 100.0% 34.2%
3672297 616.1.1.0 ↗ alpha arrays › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain 0.58 52.0 4.86e-01 100.0% 87.4%
3246869 212.1.1.0 ↗ a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like 0.58 50.0 3.57e-01 97.4% 31.2%
4491672 601.7.1.6 ↗ alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › GlnD_UR_UTase 0.58 48.0 3.76e-01 90.8% 67.5%
3277600 5059.1.1.1 ↗ alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA 0.58 51.0 3.37e-01 100.0% 77.8%
3773794 6170.1.1.25 ↗ alpha bundles › Kv7 proximal C-terminal Domain › Kv7 proximal C-terminal Domain › Kv7 proximal C-terminal Domain › PF30874 0.57 49.0 4.75e-01 100.0% 88.2%
3458081 109.4.1.543 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › efThoc1 0.57 48.0 3.61e-01 96.1% 46.2%
3519620 190.1.1.0 ↗ alpha arrays › HMG-box-like › HMG-box › HMG-box 0.56 45.0 4.08e-01 89.5% 63.6%
4077080 5045.1.1.1 ↗ alpha bundles › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › ATP-synt_A 0.56 48.0 3.37e-01 98.7% 29.0%
2145114 1075.4.1.1 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane 0.56 48.0 3.21e-01 100.0% 35.8%
4979047 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.56 48.0 3.82e-01 100.0% 48.5%
3288662 620.1.1.5 ↗ alpha bundles › YfiT-like putative metal-dependent hydrolases › YfiT-like putative metal-dependent hydrolases › YfiT-like putative metal-dependent hydrolases › MDMPI_N 0.55 48.0 3.84e-01 98.7% 72.3%
3591474 4106.1.1.1 ↗ few secondary structure elements › Zinc hairpin stack › Zinc hairpin stack › Zinc hairpin stack › DHHC 0.55 48.0 3.50e-01 100.0% 76.4%
3291596 150.5.1.52 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › PE 0.55 47.0 4.34e-01 98.7% 75.0%
4946356 620.1.1.0 ↗ alpha bundles › YfiT-like putative metal-dependent hydrolases › YfiT-like putative metal-dependent hydrolases › YfiT-like putative metal-dependent hydrolases 0.53 44.0 3.60e-01 92.1% 77.2%
3743940 632.22.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.53 46.0 3.69e-01 100.0% 93.1%
3612380 605.1.1.0 ↗ alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.53 46.0 4.40e-01 97.4% 83.3%
3978753 3759.1.1.1 ↗ alpha arrays › Antitermination protein Q helical domain › Antitermination protein Q helical domain › Antitermination protein Q helical domain › Antiterm 0.52 45.0 3.81e-01 97.4% 91.5%
3960953 2004.1.1.85 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ArsA_ATPase 0.50 44.0 2.79e-01 96.1% 21.3%
5083333 4207.1.2.0 ↗ alpha duplicates or obligate multimers › Mediator hinge subcomplex-like › Mediator hinge subcomplex-like › MED7 hinge region 0.50 42.0 3.36e-01 94.7% 46.7%
D5 medium residues 164-248_401-419
PDB
Domain cluster: representative
CATH (65)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3qxbA00 3.20.20.150 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Divalent-metal-dependent TIM barrel enzymes 0.65 50.0 3.61e-01 81.7% 53.5%
5vanA02 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.64 49.0 3.29e-01 81.7% 43.3%
6p8vA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.64 49.0 3.90e-01 81.7% 50.7%
4v2xA01 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.64 49.0 3.42e-01 81.7% 51.8%
3qyqA00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.63 48.0 3.58e-01 81.7% 57.1%
3m1rB01 3.40.800.10 Alpha Beta › 3-Layer(aba) Sandwich › Arginase; Chain A › Ureohydrolase domain 0.63 48.0 3.51e-01 81.7% 51.7%
4j3fA00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.63 48.0 3.60e-01 81.7% 72.6%
4wiaC00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.62 44.0 3.38e-01 73.1% 73.0%
2ayiA01 3.40.1830.10 Alpha Beta › 3-Layer(aba) Sandwich › Thermophilic metalloprotease-like › Thermophilic metalloprotease (M29) 0.62 47.0 4.02e-01 81.7% 76.0%
8b73B01 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.62 47.0 3.35e-01 81.7% 67.0%
7swlB01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.61 47.0 4.03e-01 81.7% 81.0%
2cunA02 3.40.50.1260 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Phosphoglycerate kinase, N-terminal domain 0.61 54.0 4.34e-01 97.1% 99.0%
4icsA01 3.40.1830.10 Alpha Beta › 3-Layer(aba) Sandwich › Thermophilic metalloprotease-like › Thermophilic metalloprotease (M29) 0.61 46.0 3.90e-01 81.7% 72.1%
3ozoA02 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.61 52.0 3.58e-01 97.1% 94.3%
3d3aA01 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.61 48.0 3.54e-01 84.6% 89.8%
3milB00 3.40.50.1110 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SGNH hydrolase 0.61 46.0 3.56e-01 81.7% 36.1%
8d89A01 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.60 52.0 3.54e-01 95.2% 86.9%
4k7jA01 3.40.50.1110 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SGNH hydrolase 0.59 45.0 3.50e-01 79.8% 55.3%
1e5nA00 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.59 45.0 3.16e-01 81.7% 36.7%
4f8xA00 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.59 45.0 3.20e-01 81.7% 62.1%
4ydsA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.59 45.0 3.52e-01 81.7% 52.7%
5b5lA00 3.40.50.1110 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SGNH hydrolase 0.59 45.0 3.63e-01 81.7% 68.1%
3niyA00 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.59 48.0 3.38e-01 88.5% 89.9%
1c7sA03 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.58 50.0 3.29e-01 98.1% 98.6%
4ltyA01 3.60.21.10 Alpha Beta › 4-Layer Sandwich › Purple Acid Phosphatase; chain A, domain 2 › Metallo-dependent phosphatases 0.58 50.0 3.70e-01 97.1% 98.2%
3av0A01 3.60.21.10 Alpha Beta › 4-Layer Sandwich › Purple Acid Phosphatase; chain A, domain 2 › Metallo-dependent phosphatases 0.58 50.0 3.84e-01 97.1% 98.4%
3fbsB01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.58 50.0 4.11e-01 95.2% 97.3%
3ndzA00 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.57 49.0 3.43e-01 94.2% 90.1%
2jieA00 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.57 50.0 3.31e-01 98.1% 94.8%
5bt8A02 3.40.50.1260 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Phosphoglycerate kinase, N-terminal domain 0.57 50.0 3.93e-01 97.1% 91.8%
3q9cA00 3.40.800.20 Alpha Beta › 3-Layer(aba) Sandwich › Arginase; Chain A › Histone deacetylase domain 0.56 43.0 3.04e-01 81.7% 43.7%
3tscA00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.56 48.0 3.63e-01 96.2% 95.9%
2jepB00 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.56 49.0 3.43e-01 99.0% 93.9%
1dtnA02 3.20.20.120 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Enolase-like C-terminal domain 0.56 45.0 3.52e-01 88.5% 87.0%
3qldA02 3.20.20.120 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Enolase-like C-terminal domain 0.56 46.0 3.58e-01 90.4% 88.3%
1uf3A00 3.60.21.10 Alpha Beta › 4-Layer Sandwich › Purple Acid Phosphatase; chain A, domain 2 › Metallo-dependent phosphatases 0.56 49.0 3.82e-01 98.1% 99.1%
4ntcA01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.55 48.0 3.91e-01 98.1% 95.5%
3n8hA01 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.55 49.0 4.16e-01 100.0% 92.0%
4w88B00 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.55 47.0 3.26e-01 92.3% 94.1%
3fkkA00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.55 49.0 3.51e-01 99.0% 99.3%
1geqB00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.55 48.0 3.63e-01 96.2% 97.6%
3nbkD00 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.54 48.0 4.14e-01 97.1% 73.0%
5bmoC00 3.40.50.10320 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › LmbE-like 0.54 47.0 3.61e-01 96.2% 94.2%
2hzgA02 3.20.20.120 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Enolase-like C-terminal domain 0.54 43.0 3.32e-01 87.5% 86.3%
1n3lA01 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.54 46.0 3.76e-01 96.2% 86.1%
1khdD02 3.40.1030.10 Alpha Beta › 3-Layer(aba) Sandwich › Pyrimidine Nucleoside Phosphorylase; Chain A, domain 2 › Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 0.54 47.0 3.69e-01 97.1% 93.7%
3aamA00 3.20.20.150 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Divalent-metal-dependent TIM barrel enzymes 0.54 41.0 3.07e-01 81.7% 61.3%
1n0uA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.53 42.0 3.43e-01 86.5% 71.0%
1dctA01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.53 41.0 3.46e-01 81.7% 73.4%
4ix1A00 3.40.50.12500 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.53 33.0 2.62e-01 80.8% 27.4%
2q2rA02 3.40.367.20 Alpha Beta › 3-Layer(aba) Sandwich › Hexokinase; domain 1 › 0.53 40.0 3.27e-01 81.7% 85.2%
3co8A02 3.20.20.10 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Alanine racemase 0.53 40.0 3.19e-01 81.7% 39.6%
2vyoA00 3.20.20.370 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycoside hydrolase/deacetylase 0.53 46.0 3.70e-01 97.1% 87.9%
1wraA01 3.60.15.10 Alpha Beta › 4-Layer Sandwich › Metallo-beta-lactamase; Chain A › Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 0.52 45.0 3.28e-01 96.2% 70.3%
4f6cB00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.52 45.0 3.10e-01 96.2% 67.9%
2cycA01 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.51 44.0 3.50e-01 97.1% 85.8%
3elbA02 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.51 45.0 3.93e-01 99.0% 78.8%
1o5wA01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.51 45.0 3.69e-01 99.0% 100.0%
3i8oA01 3.40.50.1010 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 5'-nuclease 0.51 43.0 4.10e-01 95.2% 100.0%
5d8nA01 3.40.220.10 Alpha Beta › 3-Layer(aba) Sandwich › Leucine Aminopeptidase, subunit E; domain 1 › Leucine Aminopeptidase, subunit E, domain 1 0.51 37.0 3.07e-01 76.0% 78.7%
3elbA01 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.51 44.0 4.05e-01 97.1% 88.3%
1ur1A00 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.51 43.0 3.10e-01 98.1% 92.8%
1ipaA02 3.40.1280.10 Alpha Beta › 3-Layer(aba) Sandwich › Alpha/beta knot › SPOUT methyltransferase, trefoil knot domain 0.51 44.0 3.89e-01 97.1% 93.5%
4epkB00 3.20.20.140 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Metal-dependent hydrolases 0.50 40.0 2.84e-01 85.6% 90.6%
3wsfA02 3.40.1390.30 Alpha Beta › 3-Layer(aba) Sandwich › Udp-n-acetylmuramoylalanyl-d-glutamate--2,6- Diaminopimelate Ligase; Chain: A, domain 1 › NIF3 (NGG1p interacting factor 3)-like 0.50 36.0 3.48e-01 81.7% 66.7%
ECOD (82)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3629727 2004.1.1.1 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA 0.71 55.0 4.16e-01 81.7% 50.2%
5070004 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.70 54.0 4.76e-01 81.7% 87.3%
4996622 2004.1.1.1 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA 0.68 53.0 4.28e-01 81.7% 52.3%
3255731 2004.1.1.1 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA 0.68 52.0 4.16e-01 81.7% 57.6%
5002767 2004.1.1.1 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA 0.67 52.0 4.27e-01 81.7% 50.8%
3717015 2004.1.1.1 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA 0.67 52.0 4.27e-01 81.7% 54.1%
4028442 2004.1.1.1 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA 0.66 51.0 4.18e-01 81.7% 55.1%
3275379 2004.1.1.1 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA 0.65 50.0 4.08e-01 81.7% 49.2%
3875443 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.65 49.0 3.61e-01 81.7% 33.6%
4011899 2006.1.5.1 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Arginase/deacetylase › Arginase 0.65 44.0 3.25e-01 71.2% 69.0%
3641662 2004.1.1.530 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA, AAA_lid_3 0.64 49.0 3.42e-01 81.7% 26.8%
3480385 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.64 49.0 3.77e-01 81.7% 39.2%
3601397 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.64 49.0 3.50e-01 81.7% 42.5%
4016893 2004.1.1.1 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA 0.64 49.0 3.63e-01 81.7% 35.3%
4947766 2004.1.1.1 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA 0.64 49.0 3.92e-01 81.7% 51.0%
3609341 2004.1.1.1 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA 0.64 49.0 3.61e-01 81.7% 34.6%
5055179 2484.1.1.302 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB 0.63 48.0 3.82e-01 81.7% 94.3%
5024268 2002.1.1.44 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › TatD_DNase 0.62 48.0 3.49e-01 81.7% 55.3%
2573569 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.62 47.0 3.59e-01 81.7% 39.0%
4997554 2484.1.1.124 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › OrfB_IS605 0.62 46.0 4.08e-01 77.9% 98.0%
3284433 2007.1.19.2 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › FabD/lysophospholipase-like › Patatin 0.62 46.0 3.29e-01 78.8% 87.1%
3589086 7590.1.1.1 ↗ a/b three-layered sandwiches › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs › Peptidase_M29 0.61 47.0 3.92e-01 81.7% 71.4%
4936255 2004.1.1.202 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_28 0.61 44.0 3.59e-01 75.0% 85.5%
5004517 2484.1.1.302 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB 0.61 47.0 3.76e-01 81.7% 73.8%
4961847 2484.1.1.302 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB 0.61 51.0 4.05e-01 91.3% 95.8%
3500854 7529.1.1.11 ↗ a/b three-layered sandwiches › Macro domain-like › Macro domain-like › Macro domain-like › DUF2362 0.61 47.0 3.22e-01 81.7% 59.2%
4330520 300.1.1.0 ↗ a+b three layers › Phospholipase D/nuclease › Phospholipase D/nuclease › Phospholipase D/nuclease 0.61 53.0 3.44e-01 97.1% 24.3%
3869764 300.1.1.0 ↗ a+b three layers › Phospholipase D/nuclease › Phospholipase D/nuclease › Phospholipase D/nuclease 0.60 53.0 4.08e-01 97.1% 49.6%
3510221 300.1.1.0 ↗ a+b three layers › Phospholipase D/nuclease › Phospholipase D/nuclease › Phospholipase D/nuclease 0.60 53.0 3.99e-01 96.2% 46.8%
4456464 2002.1.1.8 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Cellulase 0.60 50.0 3.42e-01 91.3% 90.9%
5077987 2006.1.6.12 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA_2 0.60 44.0 3.54e-01 78.8% 84.2%
5036143 2004.1.1.1199 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DUF499 0.60 45.0 3.26e-01 81.7% 35.6%
3487369 7529.1.1.11 ↗ a/b three-layered sandwiches › Macro domain-like › Macro domain-like › Macro domain-like › DUF2362 0.59 46.0 3.54e-01 81.7% 80.4%
4635994 300.1.1.0 ↗ a+b three layers › Phospholipase D/nuclease › Phospholipase D/nuclease › Phospholipase D/nuclease 0.59 52.0 3.99e-01 97.1% 53.8%
4057956 2004.1.1.35 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Bac_DnaA 0.59 45.0 3.49e-01 81.7% 53.0%
4999337 2484.1.1.124 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › OrfB_IS605 0.58 45.0 3.97e-01 82.7% 94.2%
5048623 2005.1.1.13 ↗ a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › CTP_transf_like 0.58 51.0 4.22e-01 96.2% 67.2%
5075755 2484.1.1.124 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › OrfB_IS605 0.58 51.0 4.40e-01 97.1% 99.4%
4979584 2005.1.1.13 ↗ a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › CTP_transf_like 0.58 50.0 4.41e-01 96.2% 81.9%
5044659 2002.1.1.102 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › PHP 0.57 45.0 3.62e-01 85.6% 94.9%
3949157 2005.1.1.35 ↗ a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › Citrate_ly_lig 0.57 52.0 4.07e-01 100.0% 73.5%
4611002 2005.1.1.35 ↗ a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › Citrate_ly_lig 0.57 51.0 4.06e-01 100.0% 72.6%
4157808 2005.1.1.13 ↗ a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › CTP_transf_like 0.56 49.0 3.99e-01 97.1% 83.5%
3203047 2006.1.4.29 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › PIN-like_DDX60 0.56 46.0 3.75e-01 92.3% 78.6%
3718981 2006.1.4.0 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like 0.56 47.0 3.97e-01 95.2% 100.0%
4991997 2005.1.1.13 ↗ a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › CTP_transf_like 0.56 48.0 4.40e-01 95.2% 88.6%
3606754 2005.1.1.0 ↗ a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains 0.56 48.0 3.80e-01 97.1% 72.6%
4173456 2484.1.1.211 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › OrfB_IS605, Cas12f1-like_TNB 0.56 41.0 3.40e-01 77.9% 76.4%
5058976 246.2.1.1 ↗ a+b four layers › Carbon-nitrogen hydrolase-like › Metallo-dependent phosphatases › Metallo-dependent phosphatases › Metallophos 0.56 48.0 3.53e-01 97.1% 94.1%
4994780 2484.1.1.124 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › OrfB_IS605 0.55 47.0 3.80e-01 96.2% 98.1%
5043276 2005.1.1.13 ↗ a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › CTP_transf_like 0.55 49.0 4.29e-01 96.2% 79.1%
3286637 2484.1.1.124 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › OrfB_IS605 0.55 41.0 3.58e-01 78.8% 90.3%
4298289 246.2.1.1 ↗ a+b four layers › Carbon-nitrogen hydrolase-like › Metallo-dependent phosphatases › Metallo-dependent phosphatases › Metallophos 0.55 48.0 3.60e-01 97.1% 98.9%
3603327 2484.1.1.59 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › NurA 0.55 45.0 3.11e-01 91.3% 81.2%
3178498 2484.1.1.57 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Ydc2-catalyt 0.55 48.0 3.55e-01 99.0% 78.3%
4934333 246.2.1.9 ↗ a+b four layers › Carbon-nitrogen hydrolase-like › Metallo-dependent phosphatases › Metallo-dependent phosphatases › Metallophos_2 0.55 47.0 3.61e-01 96.2% 97.6%
None — 0.55 47.0 3.53e-01 94.2% 91.3%
4123648 2005.1.1.13 ↗ a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › CTP_transf_like 0.55 48.0 4.08e-01 97.1% 74.0%
3956669 2484.1.1.124 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › OrfB_IS605 0.54 42.0 3.56e-01 82.7% 90.0%
5038403 246.2.1.1 ↗ a+b four layers › Carbon-nitrogen hydrolase-like › Metallo-dependent phosphatases › Metallo-dependent phosphatases › Metallophos 0.54 41.0 3.48e-01 81.7% 81.1%
4440430 2002.1.1.15 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Trp_syntA 0.54 47.0 3.51e-01 95.2% 94.7%
4107596 2002.1.1.83 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Amidohydro_1 0.54 46.0 3.28e-01 100.0% 82.2%
5071044 7601.1.1.2 ↗ a/b three-layered sandwiches › Lactate racemase N-terminal domain › Lactate racemase N-terminal domain › Lactate racemase N-terminal domain › DUF362 0.54 46.0 3.23e-01 96.2% 71.5%
3512158 2005.1.1.13 ↗ a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › CTP_transf_like 0.54 46.0 4.07e-01 94.2% 83.3%
3944963 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.53 41.0 3.36e-01 81.7% 84.2%
3602729 2002.1.1.15 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Trp_syntA 0.53 48.0 3.49e-01 98.1% 89.6%
4494002 2003.1.1.20 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › Epimerase 0.53 39.0 3.80e-01 78.8% 97.5%
4083092 2005.1.1.21 ↗ a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › Pantoate_ligase 0.53 47.0 3.98e-01 100.0% 90.0%
3795398 7570.1.1.0 ↗ a/b three-layered sandwiches › MurD-like peptide ligases, peptide-binding domain › MurD-like peptide ligases, peptide-binding domain › MurD-like peptide ligases, peptide-binding domain 0.53 41.0 3.61e-01 86.5% 81.2%
3184194 2484.1.1.48 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › MutS_II 0.52 44.0 3.73e-01 97.1% 95.8%
4180692 2002.1.1.66 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › DHquinase_I 0.52 44.0 3.38e-01 93.3% 95.4%
3172513 2484.1.1.48 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › MutS_II 0.52 44.0 3.80e-01 96.2% 91.8%
4667958 2002.1.1.0 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels 0.52 43.0 3.38e-01 92.3% 96.2%
5023003 2005.1.1.3 ↗ a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › Usp 0.52 45.0 4.19e-01 96.2% 99.2%
3602374 2002.1.1.418 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › DUF7388 0.52 45.0 3.45e-01 93.3% 97.8%
3502906 2007.9.1.2 ↗ a/b three-layered sandwiches › Flavodoxin-like › Toll/Interleukin receptor TIR domain › Toll/Interleukin receptor TIR domain › SEFIR 0.52 38.0 3.49e-01 79.8% 96.6%
5014091 2002.1.1.447 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › DUF5981 0.51 43.0 3.01e-01 91.3% 77.4%
3165826 2487.1.1.9 ↗ a/b three-layered sandwiches › "The ""swivelling"" beta/beta/alpha domains" › "The ""swivelling"" beta/beta/alpha domain" › "The ""swivelling"" beta/beta/alpha domain" › Cyclase 0.51 39.0 3.66e-01 81.7% 81.5%
5000484 2004.1.1.192 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_18 0.51 39.0 3.37e-01 82.7% 98.8%
1381490 2002.1.1.86 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Glyco_hydro_59 0.51 44.0 3.28e-01 100.0% 90.8%
2391702 2484.1.1.31 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Glucokinase 0.51 40.0 3.08e-01 84.6% 87.2%
3364356 2488.1.1.12 ↗ a/b three-layered sandwiches › alpha/beta knot › alpha/beta knot › alpha/beta knot › Methyltrans_RNA 0.50 42.0 4.01e-01 94.2% 95.2%