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SR-VP_0-2_scaffold_141_2072294_prodigal-single.1__X__X__00001
Bact-VirSR-VP_0-2_scaffold_141_2072294_prodigal-single.1__X__X__00001
Identity
- Kingdom:
- phage
Quality
90.9
mean pLDDT
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 837-881
Domain cluster:
representative
CATH (1)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1epuA01 | 3.40.50.2060 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Sec1/Munc18 (SM) protein, domain 1 | 0.51 | 39.0 | 2.92e-01 | 86.7% | 80.5% |
ECOD (5)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4035686 | 4959.1.1.1 ↗ | a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_3 | 0.75 | 63.0 | 4.52e-01 | 100.0% | 32.9% |
| 4516064 | 4959.1.1.1 ↗ | a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_3 | 0.75 | 64.0 | 4.49e-01 | 100.0% | 30.7% |
| 4424574 | 4959.1.1.0 ↗ | a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit | 0.71 | 63.0 | 4.58e-01 | 100.0% | 37.5% |
| 4159854 | 7554.1.1.1 ↗ | a/b three-layered sandwiches › 2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain › 2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain › 2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain › iPGM_N | 0.57 | 46.0 | 3.03e-01 | 100.0% | 50.0% |
| 4021782 | 213.1.1.0 ↗ | a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) | 0.51 | 38.0 | 2.50e-01 | 82.2% | 49.5% |
D2
medium
residues 1-51
Domain cluster:
representative
CATH (1)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1uouA03 | 3.90.1170.30 | Alpha Beta › Alpha-Beta Complex › Aldehyde Oxidoreductase; domain 3 › Pyrimidine nucleoside phosphorylase-like, C-terminal domain | 0.53 | 44.0 | 3.72e-01 | 94.1% | 55.1% |
ECOD (18)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4310351 | 325.1.7.0 ↗ | a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif | 0.91 | 71.0 | 6.27e-01 | 82.4% | 60.0% |
| 4505755 | 325.1.7.0 ↗ | a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif | 0.90 | 71.0 | 6.32e-01 | 84.3% | 61.4% |
| 4587689 | 325.1.7.0 ↗ | a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif | 0.89 | 70.0 | 6.09e-01 | 84.3% | 57.3% |
| 4352841 | 325.1.7.0 ↗ | a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif | 0.88 | 70.0 | 5.97e-01 | 86.3% | 55.0% |
| 4054539 | 325.1.7.2 ↗ | a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › RNA_pol_Rpb2_6 | 0.88 | 70.0 | 5.93e-01 | 86.3% | 55.0% |
| 4477076 | 325.1.7.0 ↗ | a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif | 0.86 | 66.0 | 5.62e-01 | 82.4% | 52.5% |
| 4054448 | 325.1.7.0 ↗ | a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif | 0.86 | 67.0 | 5.98e-01 | 86.3% | 61.4% |
| 4887391 | 4042.1.1.1 ↗ | a+b complex topology › barrel domain in beta subunit of DNA dependent RNA-polymerase › barrel domain in beta subunit of DNA dependent RNA-polymerase › barrel domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_6 | 0.85 | 74.0 | 5.39e-01 | 100.0% | 36.5% |
| 4611577 | 325.1.7.0 ↗ | a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif | 0.85 | 62.0 | 5.33e-01 | 78.4% | 50.0% |
| 4049232 | 325.1.7.2 ↗ | a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › RNA_pol_Rpb2_6 | 0.84 | 66.0 | 5.71e-01 | 86.3% | 55.0% |
| 4359531 | 325.1.7.0 ↗ | a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif | 0.84 | 66.0 | 5.70e-01 | 86.3% | 55.0% |
| 4190015 | 325.1.7.0 ↗ | a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif | 0.84 | 62.0 | 4.91e-01 | 78.4% | 40.0% |
| 4203681 | 325.1.7.0 ↗ | a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif | 0.84 | 65.0 | 5.60e-01 | 84.3% | 54.4% |
| 4459871 | 325.1.7.0 ↗ | a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif | 0.83 | 65.0 | 5.70e-01 | 86.3% | 57.3% |
| 4876256 | 1.1.2.1 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi › RNA_pol_Rpb2_6 | 0.83 | 64.0 | 5.53e-01 | 86.3% | 54.4% |
| 4052358 | 325.1.7.0 ↗ | a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif | 0.75 | 55.0 | 5.00e-01 | 80.4% | 60.0% |
| 4216608 | 325.1.7.0 ↗ | a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif | 0.73 | 55.0 | 4.83e-01 | 84.3% | 53.8% |
| 4555851 | 325.1.7.0 ↗ | a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif | 0.71 | 52.0 | 4.24e-01 | 78.4% | 43.2% |
D3
medium
residues 52-84_203-303
Domain cluster:
rep: RNA_polymerase_subunit_RPO132__YP_009046186__Penguinpox_virus__648998__D714-766_870-915_991-1015
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00562.34 best | RNA_pol_Rpb2_6 | 49.8 | 4.00e-13 | 80.6% | 27.4% |
CATH (3)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1twfB06 | 2.40.270.10 | Mainly Beta › Beta Barrel › Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; Domain 6 › DNA-directed RNA polymerase, subunit 2, domain 6 | 0.89 | 85.0 | 6.97e-01 | 100.0% | 64.6% |
| 1hqmC01 | 2.40.270.10 | Mainly Beta › Beta Barrel › Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; Domain 6 › DNA-directed RNA polymerase, subunit 2, domain 6 | 0.88 | 84.0 | 7.00e-01 | 100.0% | 88.0% |
| 3umbA02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.54 | 24.0 | 3.05e-01 | 76.1% | 68.4% |
ECOD (17)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3613807 | 1.1.2.1 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi › RNA_pol_Rpb2_6 | 0.91 | 88.0 | 7.88e-01 | 100.0% | 86.9% |
| 4167437 | 1.1.2.1 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi › RNA_pol_Rpb2_6 | 0.91 | 88.0 | 7.56e-01 | 100.0% | 89.7% |
| 4118150 | 1.1.2.1 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi › RNA_pol_Rpb2_6 | 0.91 | 88.0 | 8.07e-01 | 100.0% | 87.3% |
| 4492078 | 1.1.2.1 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi › RNA_pol_Rpb2_6 | 0.91 | 88.0 | 6.88e-01 | 100.0% | 90.8% |
| 4902571 | 1.1.2.32 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi › RNA_pol_Rpb2_6, RNA_pol_Rpb2_7 | 0.91 | 87.0 | 8.09e-01 | 99.3% | 87.5% |
| 4888118 | 1.1.2.1 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi › RNA_pol_Rpb2_6 | 0.91 | 87.0 | 8.08e-01 | 99.3% | 87.5% |
| 4024674 | 1.1.2.1 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi › RNA_pol_Rpb2_6 | 0.91 | 87.0 | 7.09e-01 | 100.0% | 90.7% |
| 4655578 | 1.1.2.1 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi › RNA_pol_Rpb2_6 | 0.90 | 87.0 | 7.01e-01 | 100.0% | 90.4% |
| 4148017 | 1.1.2.1 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi › RNA_pol_Rpb2_6 | 0.90 | 87.0 | 7.09e-01 | 100.0% | 90.5% |
| 4039119 | 1.1.2.1 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi › RNA_pol_Rpb2_6 | 0.89 | 86.0 | 6.75e-01 | 100.0% | 91.6% |
| 3600872 | 1.1.2.0 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi | 0.89 | 86.0 | 7.88e-01 | 100.0% | 89.1% |
| 4636141 | 1.1.2.1 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi › RNA_pol_Rpb2_6 | 0.89 | 85.0 | 7.56e-01 | 100.0% | 87.8% |
| 4946077 | 1.1.2.1 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi › RNA_pol_Rpb2_6 | 0.88 | 85.0 | 7.89e-01 | 100.0% | 88.7% |
| 4921633 | 1.1.2.1 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi › RNA_pol_Rpb2_6 | 0.87 | 84.0 | 7.09e-01 | 100.0% | 90.7% |
| 4026622 | 1.1.2.1 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi › RNA_pol_Rpb2_6 | 0.86 | 82.0 | 7.32e-01 | 100.0% | 86.1% |
| 4896460 | 1.1.2.32 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi › RNA_pol_Rpb2_6, RNA_pol_Rpb2_7 | 0.75 | 59.0 | 6.10e-01 | 82.1% | 88.4% |
| 4896487 | 1.1.2.1 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi › RNA_pol_Rpb2_6 | 0.75 | 59.0 | 6.00e-01 | 81.3% | 87.6% |
D4
medium
residues 85-192
Domain cluster:
rep: putative_RNA_polymerase_beta_subunit__YP_009052296__Aureococcus_anophagefferens_virus__1474867__D765-873
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00562.34 best | RNA_pol_Rpb2_6 | 31.5 | 1.40e-07 | 100.0% | 23.6% |
D5
medium
residues 344-392_804-833
Domain cluster:
representative
D6
medium
residues 470-571
Domain cluster:
representative
CATH (27)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2r5sA02 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.66 | 33.0 | 3.60e-01 | 74.5% | 56.8% |
| 1dd3A01 | 1.20.5.710 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Single helix bin | 0.63 | 32.0 | 4.20e-01 | 73.5% | 89.5% |
| 2o57A01 | 1.10.287.840 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Mycolic acid cyclopropane synthase domain like | 0.59 | 37.0 | 3.70e-01 | 87.3% | 61.0% |
| 6xy4A01 | 1.10.437.10 | Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like | 0.58 | 34.0 | 3.23e-01 | 81.4% | 48.8% |
| 1u3dA02 | 1.25.40.80 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.57 | 39.0 | 3.56e-01 | 75.5% | 53.0% |
| 2vf7B01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.57 | 52.0 | 3.61e-01 | 100.0% | 35.7% |
| 4rngC00 | 1.20.1280.290 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.56 | 37.0 | 4.10e-01 | 77.5% | 81.9% |
| 2x6hA03 | 1.10.1070.11 | Mainly Alpha › Orthogonal Bundle › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, Domain 5 › Phosphatidylinositol 3-/4-kinase, catalytic domain | 0.56 | 43.0 | 3.53e-01 | 84.3% | 63.5% |
| 5jrtA00 | 1.10.150.50 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Transcription Factor, Ets-1 | 0.55 | 32.0 | 3.88e-01 | 84.3% | 90.6% |
| 1pu6A02 | 1.10.340.30 | Mainly Alpha › Orthogonal Bundle › Endonuclease III; domain 1 › Hypothetical protein; domain 2 | 0.54 | 41.0 | 3.88e-01 | 80.4% | 97.6% |
| 2i1qA01 | 1.10.150.20 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 5' to 3' exonuclease, C-terminal subdomain | 0.54 | 31.0 | 3.80e-01 | 83.3% | 91.9% |
| 3bs7A00 | 1.10.150.50 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Transcription Factor, Ets-1 | 0.53 | 33.0 | 3.82e-01 | 87.3% | 85.3% |
| 4ymuD00 | 1.10.3720.10 | Mainly Alpha › Orthogonal Bundle › MetI-like fold › MetI-like | 0.53 | 36.0 | 2.93e-01 | 90.2% | 33.5% |
| 2ib0A01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.52 | 43.0 | 3.87e-01 | 87.3% | 74.8% |
| 3bvoA02 | 1.20.1280.20 | Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain | 0.52 | 33.0 | 3.65e-01 | 93.1% | 77.9% |
| 1tjoB00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.52 | 43.0 | 3.69e-01 | 95.1% | 65.7% |
| 6f1eA01 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.51 | 39.0 | 3.53e-01 | 80.4% | 61.2% |
| 2qwoB00 | 1.10.287.110 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › DnaJ domain | 0.51 | 39.0 | 4.07e-01 | 85.3% | 88.0% |
| 3zxsC02 | 1.25.40.80 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.51 | 38.0 | 3.36e-01 | 79.4% | 64.9% |
| 2wcjA00 | 1.10.238.20 | Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › Pheromone/general odorant binding protein domain | 0.51 | 40.0 | 3.65e-01 | 85.3% | 82.3% |
| 3bg2A01 | 1.10.3210.10 | Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432 | 0.51 | 39.0 | 3.28e-01 | 84.3% | 99.5% |
| 1z1vA00 | 1.10.150.50 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Transcription Factor, Ets-1 | 0.51 | 31.0 | 3.70e-01 | 85.3% | 91.4% |
| 1pmiA02 | 1.10.441.10 | Mainly Alpha › Orthogonal Bundle › Phosphomannose Isomerase; domain 2 › Phosphomannose Isomerase, domain 2 | 0.50 | 40.0 | 3.68e-01 | 86.3% | 93.4% |
| 4f91B04 | 1.10.3380.10 | Mainly Alpha › Orthogonal Bundle › Sec63 N-terminal domain-like fold › Sec63 N-terminal domain-like domain | 0.50 | 41.0 | 3.68e-01 | 89.2% | 63.4% |
| 1lk3A00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.50 | 42.0 | 3.81e-01 | 90.2% | 98.5% |
| 4x5mA00 | 1.20.1280.290 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.50 | 31.0 | 3.38e-01 | 81.4% | 74.4% |
| 4f92B10 | 1.10.3380.10 | Mainly Alpha › Orthogonal Bundle › Sec63 N-terminal domain-like fold › Sec63 N-terminal domain-like domain | 0.50 | 39.0 | 3.51e-01 | 84.3% | 79.7% |
ECOD (18)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4889091 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.89 | 84.0 | 5.45e-01 | 100.0% | 40.8% |
| 4513601 | 4246.1.1.0 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit | 0.89 | 83.0 | 5.12e-01 | 100.0% | 34.3% |
| 3951780 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.88 | 83.0 | 5.31e-01 | 100.0% | 52.6% |
| 4090024 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.88 | 83.0 | 5.58e-01 | 100.0% | 40.9% |
| 4887352 | 4246.1.1.4 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_2, RNA_pol_Rpb1_1 | 0.88 | 82.0 | 5.59e-01 | 100.0% | 46.3% |
| 4629506 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.87 | 82.0 | 5.59e-01 | 100.0% | 34.9% |
| 2067927 | 4246.1.1.0 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit | 0.78 | 71.0 | 4.86e-01 | 100.0% | 40.2% |
| 4634767 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.77 | 70.0 | 4.90e-01 | 100.0% | 41.6% |
| 3892026 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.62 | 44.0 | 3.70e-01 | 73.5% | 72.1% |
| 3919078 | 109.4.1.14 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › MyTH4 | 0.55 | 42.0 | 3.40e-01 | 79.4% | 61.1% |
| 3491802 | 109.4.1.14 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › MyTH4 | 0.55 | 41.0 | 3.37e-01 | 79.4% | 60.5% |
| 3186734 | 109.4.1.1259 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HEAT_PBS, HEAT_2 | 0.55 | 45.0 | 3.14e-01 | 89.2% | 49.6% |
| 3646179 | 4030.1.1.20 ↗ | alpha bundles › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz › Ovate | 0.54 | 29.0 | 3.93e-01 | 73.5% | 100.0% |
| 3816775 | 109.4.1.1259 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HEAT_PBS, HEAT_2 | 0.54 | 41.0 | 2.96e-01 | 81.4% | 85.7% |
| 3310955 | 630.1.1.1 ↗ | a+b complex topology › RuBisCo LSMT C-terminal, substrate-binding domain › RuBisCo LSMT C-terminal, substrate-binding domain › RuBisCo LSMT C-terminal, substrate-binding domain › Rubis-subs-bind | 0.53 | 41.0 | 3.80e-01 | 81.4% | 65.4% |
| 1261672 | 622.1.1.1 ↗ | alpha bundles › YvfG-like › HSC20 (HSCB), C-terminal oligomerisation domain › HSC20 (HSCB), C-terminal oligomerisation domain › HSCB_C | 0.51 | 38.0 | 4.00e-01 | 79.4% | 84.8% |
| 3831558 | 206.1.1.7 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PI3_PI4_kinase | 0.51 | 42.0 | 3.01e-01 | 94.1% | 38.8% |
| 3985758 | 3236.1.1.1 ↗ | alpha complex topology › Cation-proton antiporter › Cation-proton antiporter (CPA) › Cation-proton antiporter (CPA) › Na_H_Exchanger | 0.51 | 37.0 | 2.71e-01 | 85.3% | 26.3% |
D7
medium
residues 572-650
Domain cluster:
representative
CATH (37)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3l1nA01 | 6.10.140.790 | Special › Helix non-globular › Helix Hairpins › | 0.81 | 50.0 | 6.22e-01 | 75.9% | 98.0% |
| 4b6xA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.77 | 49.0 | 5.27e-01 | 75.9% | 73.9% |
| 3uo2B02 | 1.20.1280.20 | Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain | 0.74 | 47.0 | 4.62e-01 | 75.9% | 60.7% |
| 1h7cA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.73 | 47.0 | 4.29e-01 | 75.9% | 50.5% |
| 1e52A00 | 4.10.860.10 | Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › UVR domain | 0.73 | 44.0 | 5.16e-01 | 78.5% | 87.5% |
| 3b2eF00 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.70 | 45.0 | 4.96e-01 | 74.7% | 82.3% |
| 2ic6A00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.70 | 50.0 | 5.26e-01 | 75.9% | 81.7% |
| 2pmrA00 | 1.20.1270.90 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › AF1782-like | 0.70 | 51.0 | 5.22e-01 | 89.9% | 80.3% |
| 6ynwH01 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.69 | 43.0 | 4.48e-01 | 78.5% | 67.6% |
| 2wgmA01 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.68 | 42.0 | 4.23e-01 | 79.7% | 59.8% |
| 1luwA01 | 1.10.287.990 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain | 0.68 | 44.0 | 4.82e-01 | 74.7% | 81.2% |
| 2x2vA00 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.67 | 42.0 | 4.53e-01 | 78.5% | 73.5% |
| 3ls1A00 | 1.20.120.290 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle | 0.66 | 55.0 | 4.60e-01 | 89.9% | 70.7% |
| 1hr5A00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.66 | 39.0 | 4.59e-01 | 75.9% | 95.8% |
| 1op1A00 | 1.20.81.10 | Mainly Alpha › Up-down Bundle › Receptor-associated Protein › RAP domain | 0.66 | 50.0 | 5.01e-01 | 88.6% | 79.3% |
| 1ma1A01 | 1.10.287.990 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain | 0.65 | 41.0 | 4.50e-01 | 74.7% | 79.7% |
| 4e4eA01 | 1.10.287.990 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain | 0.65 | 46.0 | 4.88e-01 | 74.7% | 83.1% |
| 6umqA01 | 1.20.930.60 | Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › | 0.63 | 46.0 | 4.07e-01 | 77.2% | 96.5% |
| 3nbxX03 | 1.20.58.1510 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.62 | 40.0 | 3.75e-01 | 74.7% | 51.5% |
| 4q20A01 | 1.10.287.130 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain | 0.62 | 41.0 | 4.13e-01 | 72.2% | 67.1% |
| 3agtA00 | 1.20.120.50 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like | 0.61 | 50.0 | 4.26e-01 | 91.1% | 72.9% |
| 3ddhA02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.61 | 32.0 | 3.27e-01 | 77.2% | 48.1% |
| 3rh3A01 | 1.20.120.930 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein PF12889, N-terminal DUF3829 | 0.60 | 50.0 | 4.19e-01 | 89.9% | 63.2% |
| 2ktmA00 | 1.10.790.10 | Mainly Alpha › Orthogonal Bundle › Major Prion Protein › Prion/Doppel protein, beta-ribbon domain | 0.60 | 38.0 | 4.07e-01 | 83.5% | 73.5% |
| 2kg7B00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.58 | 41.0 | 3.86e-01 | 79.7% | 60.8% |
| 2vkzA02 | 3.40.47.10 | Alpha Beta › 3-Layer(aba) Sandwich › Peroxisomal Thiolase; Chain A, domain 1 › Thiolase/Chalcone synthase | 0.57 | 39.0 | 2.78e-01 | 81.0% | 21.4% |
| 3bxjA02 | 1.10.506.20 | Mainly Alpha › Orthogonal Bundle › GTPase Activation - p120GAP; domain 1 › | 0.57 | 42.0 | 3.91e-01 | 89.9% | 62.2% |
| 1sq5C00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.57 | 42.0 | 2.88e-01 | 78.5% | 88.9% |
| 1iq0A03 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.57 | 43.0 | 3.87e-01 | 89.9% | 56.9% |
| 2uv8A07 | 6.10.140.1410 | Special › Helix non-globular › Helix Hairpins › | 0.56 | 42.0 | 4.18e-01 | 79.7% | 89.4% |
| 1rqgA04 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.55 | 44.0 | 3.57e-01 | 91.1% | 45.7% |
| 3ltoA02 | 3.30.70.890 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › GHMP kinase, C-terminal domain | 0.55 | 42.0 | 3.57e-01 | 83.5% | 53.0% |
| 3r0qA02 | 2.70.160.11 | Mainly Beta › Distorted Sandwich › Hnrnp arginine n-methyltransferase1 › Hnrnp arginine n-methyltransferase1 | 0.55 | 41.0 | 3.03e-01 | 79.7% | 95.7% |
| 3qnmA02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.53 | 41.0 | 4.00e-01 | 100.0% | 74.4% |
| 2i53A02 | 1.10.472.10 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like | 0.52 | 38.0 | 3.39e-01 | 100.0% | 54.1% |
| 1a5tA03 | 1.20.272.10 | Mainly Alpha › Up-down Bundle › Zinc Finger, Delta Prime; domain 3 › | 0.52 | 46.0 | 4.08e-01 | 100.0% | 94.0% |
| 1eblA02 | 3.40.47.10 | Alpha Beta › 3-Layer(aba) Sandwich › Peroxisomal Thiolase; Chain A, domain 1 › Thiolase/Chalcone synthase | 0.50 | 38.0 | 3.19e-01 | 83.5% | 81.6% |
ECOD (52)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3293917 | 616.1.1.28 ↗ | alpha arrays › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › RNA_pol_Rpb1_1 | 0.87 | 76.0 | 6.49e-01 | 92.4% | 61.7% |
| 4261674 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.86 | 81.0 | 5.23e-01 | 100.0% | 28.1% |
| 3959944 | 3826.1.1.95 ↗ | alpha bundles › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › RNA_pol_Rpb1_1 | 0.84 | 79.0 | 7.39e-01 | 100.0% | 90.5% |
| 4001161 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.84 | 78.0 | 4.93e-01 | 100.0% | 23.8% |
| 4079870 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.84 | 78.0 | 4.94e-01 | 100.0% | 25.4% |
| 4815139 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.84 | 78.0 | 6.77e-01 | 100.0% | 74.8% |
| 3393665 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.83 | 77.0 | 4.90e-01 | 100.0% | 24.9% |
| 3166784 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.82 | 77.0 | 4.81e-01 | 100.0% | 24.6% |
| 3610049 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.81 | 76.0 | 4.83e-01 | 100.0% | 24.6% |
| 3618547 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.80 | 74.0 | 4.55e-01 | 100.0% | 18.4% |
| 3270404 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.77 | 71.0 | 4.41e-01 | 100.0% | 20.0% |
| 3488979 | 192.5.1.0 ↗ | alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat | 0.76 | 48.0 | 4.04e-01 | 75.9% | 40.8% |
| 4618805 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.76 | 46.0 | 5.36e-01 | 77.2% | 87.3% |
| 3785820 | 633.6.1.2 ↗ | alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › ACOX | 0.75 | 54.0 | 4.13e-01 | 74.7% | 61.7% |
| 3614864 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.75 | 49.0 | 3.68e-01 | 82.3% | 29.0% |
| 3589395 | 632.1.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain | 0.74 | 57.0 | 5.68e-01 | 89.9% | 80.0% |
| 3491418 | 192.8.1.0 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain | 0.73 | 52.0 | 5.33e-01 | 75.9% | 77.3% |
| 3487862 | 212.1.1.0 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like | 0.73 | 51.0 | 3.53e-01 | 75.9% | 24.2% |
| 3902100 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.72 | 51.0 | 5.00e-01 | 75.9% | 68.2% |
| 3646879 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.72 | 48.0 | 3.74e-01 | 88.6% | 34.4% |
| 5046679 | 632.11.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like | 0.71 | 54.0 | 5.70e-01 | 89.9% | 90.0% |
| 3556027 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.71 | 51.0 | 4.96e-01 | 75.9% | 68.2% |
| 3855461 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.71 | 50.0 | 4.94e-01 | 75.9% | 68.2% |
| 4162727 | 5086.1.1.12 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › Uds1 | 0.70 | 56.0 | 4.49e-01 | 84.8% | 80.0% |
| 4081214 | 605.1.1.290 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › Phage_Nu1 | 0.70 | 44.0 | 4.68e-01 | 77.2% | 72.9% |
| 3505907 | 605.4.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › ROP protein › ROP protein | 0.68 | 57.0 | 5.16e-01 | 89.9% | 70.5% |
| 4026684 | 192.20.1.7 ↗ | alpha bundles › Long alpha-hairpin › helical hairpin domain in transcriptional anti-activator ExsD › helical hairpin domain in transcriptional anti-activator ExsD › PF26729 | 0.67 | 47.0 | 4.26e-01 | 75.9% | 55.2% |
| 3839108 | 310.2.1.65 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF › MotA_ExbB | 0.65 | 45.0 | 3.80e-01 | 70.9% | 46.4% |
| 3230315 | 192.17.1.0 ↗ | alpha bundles › Long alpha-hairpin › Rabenosyn-5 Rab-binding domain-like › Rabenosyn-5 Rab-binding domain-like | 0.65 | 59.0 | 5.31e-01 | 98.7% | 97.1% |
| 4944477 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.65 | 42.0 | 3.21e-01 | 79.7% | 28.1% |
| 3286925 | 632.1.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain | 0.63 | 51.0 | 4.47e-01 | 89.9% | 70.0% |
| 3725482 | 601.16.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › FAT domain of focal adhesion kinase › FAT domain of focal adhesion kinase | 0.63 | 52.0 | 4.52e-01 | 91.1% | 76.7% |
| 5001620 | 632.1.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain | 0.63 | 51.0 | 4.66e-01 | 89.9% | 83.8% |
| 4949603 | 3718.1.1.34 ↗ | alpha bundles › Flagellar protein fliT › Flagellar protein fliT › Flagellar protein fliT › PF26161 | 0.62 | 42.0 | 4.13e-01 | 79.7% | 64.7% |
| 3174487 | 2498.5.1.0 ↗ | mixed a+b and a/b › Zincin-like › GroEL-intermediate domain like › GroEL-intermediate domain like | 0.62 | 47.0 | 3.09e-01 | 82.3% | 53.5% |
| 4141047 | 593.1.1.0 ↗ | alpha bundles › GroEL equatorial domain-like › GroEL equatorial domain-like › GroEL equatorial domain-like | 0.61 | 42.0 | 2.91e-01 | 70.9% | 39.2% |
| 5079107 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.60 | 45.0 | 3.84e-01 | 84.8% | 49.2% |
| 4961508 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.60 | 44.0 | 4.58e-01 | 79.7% | 86.7% |
| 3336677 | 605.1.1.132 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › DUF641 | 0.59 | 48.0 | 4.90e-01 | 86.1% | 94.7% |
| 3243729 | 601.21.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › FAD-dependent thiol oxidase › FAD-dependent thiol oxidase › Evr1_Alr | 0.59 | 47.0 | 3.16e-01 | 86.1% | 74.5% |
| 5039785 | 632.22.1.200 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › PF26119 | 0.57 | 46.0 | 4.36e-01 | 87.3% | 89.4% |
| 4948627 | 228.1.1.1 ↗ | a+b three layers › Fe,Mn superoxide dismutase (SOD)-C › Fe,Mn superoxide dismutase (SOD)-C › Fe,Mn superoxide dismutase (SOD)-C › Sod_Fe_C | 0.57 | 42.0 | 3.24e-01 | 78.5% | 69.1% |
| 3927546 | 601.21.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › FAD-dependent thiol oxidase › FAD-dependent thiol oxidase › Evr1_Alr | 0.56 | 43.0 | 2.93e-01 | 82.3% | 36.3% |
| 3591699 | 138.1.1.0 ↗ | alpha arrays › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain | 0.55 | 45.0 | 4.19e-01 | 89.9% | 86.0% |
| 3854050 | 604.12.1.43 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › Tim17 | 0.54 | 46.0 | 3.85e-01 | 93.7% | 73.3% |
| 3873779 | 2004.1.1.463 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Kinesin, Kinesin_assoc, Microtub_bd | 0.52 | 43.0 | 2.74e-01 | 91.1% | 52.7% |
| 3381592 | 2486.1.1.6 ↗ | a/b three-layered sandwiches › ClpP/crotonase › ClpP/crotonase › ClpP/crotonase › ACCA | 0.52 | 44.0 | 3.00e-01 | 100.0% | 76.4% |
| 3998654 | 101.1.10.1 ↗ | alpha arrays › HTH › HTH › Cyclin-like › Cyclin_N | 0.52 | 43.0 | 3.38e-01 | 92.4% | 72.4% |
| 3707211 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.52 | 38.0 | 4.05e-01 | 79.7% | 100.0% |
| 3549234 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.51 | 45.0 | 3.85e-01 | 100.0% | 76.2% |
| 3668937 | 2004.1.1.85 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ArsA_ATPase | 0.50 | 40.0 | 2.83e-01 | 92.4% | 55.4% |
| 3270034 | 3896.1.2.5 ↗ | alpha duplicates or obligate multimers › Intramembrane CDP-DAG synthetase-related › Intramembrane CDP-DAG synthetase-related › Intramembrane CDP-archaeol synthase › CTP_transf_1 | 0.50 | 42.0 | 3.46e-01 | 97.5% | 99.4% |
D8
medium
residues 681-803
Domain cluster:
rep: DNA-dependent_RNA_polymerase_subunit_rpo147__YP_232980__Vaccinia_virus__10245__D277-311_370-443
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00623.26 best | RNA_pol_Rpb1_2 | 66.6 | 4.60e-18 | 67.5% | 42.2% |
| PF00623.26 | RNA_pol_Rpb1_2 | 25.4 | 2.20e-05 | 57.7% | 40.4% |
CATH (18)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1twfA03 | 2.40.40.20 | Mainly Beta › Beta Barrel › Barwin-like endoglucanases › | 0.97 | 64.0 | 7.16e-01 | 98.4% | 82.2% |
| 1ynjD04 | 2.40.40.20 | Mainly Beta › Beta Barrel › Barwin-like endoglucanases › | 0.94 | 91.0 | 8.47e-01 | 100.0% | 88.3% |
| 3hu1A01 | 2.40.40.20 | Mainly Beta › Beta Barrel › Barwin-like endoglucanases › | 0.85 | 56.0 | 6.38e-01 | 97.6% | 86.5% |
| 1wlfA01 | 2.40.40.20 | Mainly Beta › Beta Barrel › Barwin-like endoglucanases › | 0.83 | 54.0 | 6.51e-01 | 99.2% | 97.6% |
| 7eu1A01 | 1.10.274.100 | Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › RNA polymerase Rpb1, domain 3 | 0.82 | 70.0 | 6.64e-01 | 100.0% | 76.8% |
| 1cz4A01 | 2.40.40.20 | Mainly Beta › Beta Barrel › Barwin-like endoglucanases › | 0.79 | 55.0 | 6.34e-01 | 100.0% | 95.7% |
| 1yleA02 | 2.40.40.20 | Mainly Beta › Beta Barrel › Barwin-like endoglucanases › | 0.79 | 41.0 | 5.59e-01 | 96.7% | 96.9% |
| 3ougA00 | 2.40.40.20 | Mainly Beta › Beta Barrel › Barwin-like endoglucanases › | 0.78 | 52.0 | 5.63e-01 | 100.0% | 79.2% |
| 1qcsA01 | 2.40.40.20 | Mainly Beta › Beta Barrel › Barwin-like endoglucanases › | 0.76 | 50.0 | 5.96e-01 | 99.2% | 100.0% |
| 1zc1A01 | 2.40.40.50 | Mainly Beta › Beta Barrel › Barwin-like endoglucanases › Ubiquitin fusion degradation protein UFD1, N-terminal domain | 0.74 | 58.0 | 6.29e-01 | 100.0% | 96.1% |
| 3vayA02 | 1.20.120.1600 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.64 | 26.0 | 3.11e-01 | 78.0% | 51.7% |
| 1gsaA03 | 3.30.1490.20 | Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › ATP-grasp fold, A domain | 0.62 | 33.0 | 4.42e-01 | 98.4% | 98.5% |
| 2i87A03 | 3.30.1490.20 | Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › ATP-grasp fold, A domain | 0.62 | 37.0 | 4.54e-01 | 100.0% | 98.6% |
| 6dgiA03 | 3.30.1490.20 | Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › ATP-grasp fold, A domain | 0.61 | 35.0 | 4.44e-01 | 100.0% | 100.0% |
| 1va9A00 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.53 | 36.0 | 3.71e-01 | 99.2% | 71.3% |
| 3s8iA00 | 2.40.70.10 | Mainly Beta › Beta Barrel › Cathepsin D, subunit A; domain 1 › Acid Proteases | 0.52 | 45.0 | 4.52e-01 | 94.3% | 91.9% |
| 1uh9A02 | 2.40.70.10 | Mainly Beta › Beta Barrel › Cathepsin D, subunit A; domain 1 › Acid Proteases | 0.51 | 43.0 | 4.04e-01 | 92.7% | 74.5% |
| 2b3rA00 | 2.60.40.150 | Mainly Beta › Sandwich › Immunoglobulin-like › C2 domain | 0.50 | 35.0 | 3.53e-01 | 98.4% | 71.0% |
ECOD (63)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3966248 | 1.1.2.0 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi | 0.99 | 67.0 | 6.99e-01 | 100.0% | 73.9% |
| 4556003 | 1.1.2.2 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi › RNA_pol_Rpb1_2 | 0.98 | 58.0 | 7.25e-01 | 94.3% | 90.4% |
| 4886549 | 275.1.1.1 ↗ | a+b two layers › MoeA-I/Ornithine decarboxylase-C/Reverse ferredoxin-like domain in RNA-polymerase › MoeA-I/Ornithine decarboxylase-C/Reverse ferredoxin-like domain in RNA-polymerase › MoeA-I/Ornithine decarboxylase-C/Reverse ferredoxin-like domain in RNA-polymerase › RNA_pol_Rpb1_2 | 0.97 | 94.0 | 8.55e-01 | 100.0% | 80.6% |
| 4887355 | 1.1.2.2 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi › RNA_pol_Rpb1_2 | 0.97 | 66.0 | 6.59e-01 | 100.0% | 68.5% |
| 3670775 | 1.1.2.2 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi › RNA_pol_Rpb1_2 | 0.96 | 68.0 | 6.97e-01 | 100.0% | 74.2% |
| 4129914 | 1.1.2.31 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi › RNA_pol_Rpb1_2, RNA_pol_Rpb1_3 | 0.96 | 93.0 | 7.44e-01 | 100.0% | 58.1% |
| 3596090 | 1.1.2.0 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi | 0.96 | 69.0 | 7.08e-01 | 100.0% | 75.8% |
| 3684523 | 1.1.2.2 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi › RNA_pol_Rpb1_2 | 0.96 | 68.0 | 6.79e-01 | 100.0% | 71.2% |
| 4026183 | 1.1.2.2 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi › RNA_pol_Rpb1_2 | 0.95 | 92.0 | 8.49e-01 | 100.0% | 82.7% |
| 1746098 | 1.1.2.2 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi › RNA_pol_Rpb1_2 | 0.94 | 91.0 | 7.99e-01 | 100.0% | 76.2% |
| 4890084 | 1.1.2.31 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi › RNA_pol_Rpb1_2, RNA_pol_Rpb1_3 | 0.93 | 64.0 | 6.52e-01 | 100.0% | 71.3% |
| 4809193 | 1.1.2.2 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi › RNA_pol_Rpb1_2 | 0.92 | 45.0 | 5.97e-01 | 74.0% | 82.4% |
| 2886100 | 1.1.2.0 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi | 0.91 | 87.0 | 7.29e-01 | 100.0% | 70.1% |
| 5011232 | 1.1.2.0 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi | 0.86 | 55.0 | 6.83e-01 | 97.6% | 100.0% |
| 3706161 | 1.1.2.0 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi | 0.85 | 56.0 | 6.70e-01 | 100.0% | 96.5% |
| 4977163 | 1.1.2.0 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi | 0.84 | 57.0 | 6.72e-01 | 100.0% | 96.6% |
| 5060748 | 1.1.2.0 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi | 0.84 | 59.0 | 6.25e-01 | 99.2% | 80.0% |
| 5060218 | 1.1.2.0 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi | 0.83 | 56.0 | 6.69e-01 | 96.7% | 100.0% |
| 5074983 | 1.1.2.0 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi | 0.82 | 57.0 | 6.59e-01 | 100.0% | 96.7% |
| 5053173 | 1.1.2.0 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi | 0.82 | 55.0 | 6.23e-01 | 100.0% | 88.4% |
| 4027672 | 1.1.2.8 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi › UFD1 | 0.81 | 60.0 | 6.54e-01 | 100.0% | 90.5% |
| 3597196 | 1.1.2.0 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi | 0.80 | 60.0 | 6.76e-01 | 100.0% | 98.9% |
| 3605376 | 1.1.2.8 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi › UFD1 | 0.79 | 59.0 | 6.69e-01 | 98.4% | 98.9% |
| 4943460 | 1.1.2.2 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi › RNA_pol_Rpb1_2 | 0.79 | 76.0 | 6.46e-01 | 100.0% | 81.1% |
| 3740728 | 1.1.2.0 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi | 0.79 | 53.0 | 6.21e-01 | 96.7% | 97.6% |
| 5081033 | 1.1.2.0 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi | 0.79 | 76.0 | 6.24e-01 | 100.0% | 77.5% |
| 3509068 | 1.1.2.2 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi › RNA_pol_Rpb1_2 | 0.79 | 76.0 | 6.25e-01 | 100.0% | 81.0% |
| 3360997 | 1.1.2.2 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi › RNA_pol_Rpb1_2 | 0.79 | 67.0 | 6.24e-01 | 100.0% | 73.8% |
| 3973129 | 1.13.1.0 ↗ | beta barrels › cradle loop barrel › Arginine N-succinyltransferase alpha chain C-terminal domain › Arginine N-succinyltransferase alpha chain C-terminal domain | 0.79 | 44.0 | 5.83e-01 | 99.2% | 100.0% |
| 3836120 | 275.1.1.1 ↗ | a+b two layers › MoeA-I/Ornithine decarboxylase-C/Reverse ferredoxin-like domain in RNA-polymerase › MoeA-I/Ornithine decarboxylase-C/Reverse ferredoxin-like domain in RNA-polymerase › MoeA-I/Ornithine decarboxylase-C/Reverse ferredoxin-like domain in RNA-polymerase › RNA_pol_Rpb1_2 | 0.79 | 75.0 | 6.29e-01 | 100.0% | 86.2% |
| 1883479 | 1.1.2.7 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi › CDC48_N | 0.79 | 55.0 | 6.37e-01 | 100.0% | 97.8% |
| 3698542 | 1.1.2.2 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi › RNA_pol_Rpb1_2 | 0.79 | 75.0 | 6.15e-01 | 100.0% | 80.5% |
| 4015760 | 1.1.2.0 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi | 0.78 | 75.0 | 6.27e-01 | 100.0% | 83.6% |
| 4122334 | 1.1.2.6 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi › Asp_decarbox | 0.78 | 53.0 | 5.07e-01 | 100.0% | 60.7% |
| 4948679 | 1.1.2.2 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi › RNA_pol_Rpb1_2 | 0.78 | 73.0 | 5.18e-01 | 97.6% | 45.1% |
| 5058903 | 1.1.2.2 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi › RNA_pol_Rpb1_2 | 0.78 | 74.0 | 6.26e-01 | 100.0% | 81.6% |
| 4021338 | 1.1.2.0 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi | 0.77 | 60.0 | 6.65e-01 | 100.0% | 99.0% |
| 3374701 | 1.1.2.2 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi › RNA_pol_Rpb1_2 | 0.76 | 73.0 | 6.24e-01 | 100.0% | 78.9% |
| 3927447 | 1.1.2.8 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi › UFD1 | 0.74 | 59.0 | 6.29e-01 | 100.0% | 92.7% |
| 4934824 | 1.1.2.0 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi | 0.73 | 49.0 | 5.75e-01 | 99.2% | 100.0% |
| 4030729 | 1.1.2.8 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi › UFD1 | 0.72 | 58.0 | 6.26e-01 | 100.0% | 98.1% |
| 4029174 | 1.1.2.8 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi › UFD1 | 0.72 | 56.0 | 5.49e-01 | 100.0% | 75.4% |
| 4508340 | 1.1.2.0 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi | 0.72 | 53.0 | 5.75e-01 | 100.0% | 89.5% |
| 4014411 | 1.1.2.0 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi | 0.72 | 53.0 | 5.95e-01 | 100.0% | 98.9% |
| 4441475 | 1.1.2.12 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi › PTAC | 0.71 | 51.0 | 5.65e-01 | 100.0% | 92.0% |
| 3406944 | 1.1.2.0 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi | 0.69 | 55.0 | 5.23e-01 | 100.0% | 72.1% |
| 3309021 | 1.1.2.8 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi › UFD1 | 0.69 | 58.0 | 6.18e-01 | 100.0% | 99.1% |
| 3427279 | 1.1.2.8 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi › UFD1 | 0.68 | 58.0 | 5.06e-01 | 100.0% | 61.7% |
| 4048983 | 1.1.2.0 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi | 0.68 | 53.0 | 5.71e-01 | 100.0% | 96.2% |
| 4498374 | 1.1.2.23 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi › PolC_DP2_cat | 0.68 | 64.0 | 4.97e-01 | 100.0% | 55.2% |
| 4961166 | 1.1.2.23 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi › PolC_DP2_cat | 0.68 | 64.0 | 5.00e-01 | 100.0% | 62.0% |
| 4954178 | 1.1.2.23 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi › PolC_DP2_cat | 0.68 | 64.0 | 4.19e-01 | 100.0% | 32.7% |
| 5030460 | 1.1.2.23 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi › PolC_DP2_cat | 0.68 | 64.0 | 4.14e-01 | 100.0% | 31.0% |
| 5056546 | 3349.1.1.3 ↗ | a+b two layers › DNA polymerase D large subunit DP2 N-terminal domain › DNA polymerase D large subunit DP2 N-terminal domain › DNA polymerase D large subunit DP2 N-terminal domain › PolC_DP2_cat | 0.68 | 64.0 | 4.16e-01 | 100.0% | 31.2% |
| 3772228 | 1.1.2.40 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi › PEX6_vert_N | 0.66 | 50.0 | 4.93e-01 | 97.6% | 74.6% |
| 3175987 | 1.1.2.0 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi | 0.64 | 53.0 | 4.34e-01 | 100.0% | 50.5% |
| 3684407 | 1.1.2.35 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi › PF26429 | 0.62 | 58.0 | 5.19e-01 | 100.0% | 78.2% |
| 5005269 | 1.1.2.0 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi | 0.60 | 57.0 | 5.44e-01 | 100.0% | 90.7% |
| 4013955 | 1.1.2.0 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi | 0.60 | 56.0 | 5.60e-01 | 100.0% | 97.6% |
| 4948274 | 164.1.1.1 ↗ | alpha bundles › Chorismate mutase II › Chorismate mutase II › Chorismate mutase II › CM_2 | 0.55 | 25.0 | 3.10e-01 | 74.0% | 68.0% |
| 5082058 | 164.1.1.1 ↗ | alpha bundles › Chorismate mutase II › Chorismate mutase II › Chorismate mutase II › CM_2 | 0.54 | 24.0 | 3.02e-01 | 73.2% | 66.7% |
| 4957352 | 164.1.1.1 ↗ | alpha bundles › Chorismate mutase II › Chorismate mutase II › Chorismate mutase II › CM_2 | 0.52 | 24.0 | 2.92e-01 | 74.0% | 63.7% |
| 4024013 | 4954.1.1.1 ↗ | a+b complex topology › central helical domain in RNA-polymerase beta-prime subunit › central helical domain in RNA-polymerase beta-prime subunit › central helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_5 | 0.51 | 40.0 | 3.32e-01 | 100.0% | 44.7% |