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SR-VP_0-2_scaffold_141_2510002_prodigal-single.1__X__X__00021

Bact-Vir

SR-VP_0-2_scaffold_141_2510002_prodigal-single.1__X__X__00021

Identity

Kingdom:
phage

Quality

64.2 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 30-127
PDB
CATH (74)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2lm9A00 1.20.58.970 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.88 60.0 6.13e-01 88.8% 71.9%
3mq1A01 1.20.58.970 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.87 60.0 6.21e-01 88.8% 75.0%
1j30A00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.86 56.0 4.87e-01 81.6% 46.1%
1yf2A02 1.10.287.1120 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein 0.86 77.0 7.49e-01 94.9% 99.1%
5y06A01 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.85 74.0 5.51e-01 100.0% 39.7%
4k0dA00 1.20.120.1730 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.85 71.0 6.17e-01 88.8% 99.3%
3hr0B01 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.84 65.0 7.22e-01 80.6% 100.0%
3r84A00 1.10.287.3490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.84 61.0 6.68e-01 85.7% 91.4%
1uurA01 1.20.58.240 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › STAT; domain 1 0.83 59.0 5.67e-01 92.9% 65.5%
4lwsA00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.83 68.0 6.76e-01 85.7% 86.0%
1owaA02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.82 58.0 5.64e-01 89.8% 67.0%
2qywA00 1.20.58.400 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins 0.82 57.0 5.83e-01 76.5% 73.7%
3i2wA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.82 75.0 5.39e-01 100.0% 37.2%
6tejB01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.82 74.0 5.13e-01 100.0% 32.3%
2v0xA01 1.10.287.3160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.81 74.0 6.02e-01 95.9% 56.0%
3icxA01 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.81 60.0 6.79e-01 84.7% 100.0%
4iloA00 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.81 75.0 5.53e-01 100.0% 51.3%
2dw4A03 1.10.287.80 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain 0.81 75.0 7.50e-01 100.0% 98.0%
3pltA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.81 74.0 5.67e-01 100.0% 47.2%
1kmiZ02 1.10.287.500 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.80 71.0 6.33e-01 100.0% 70.1%
3ajwA00 1.10.287.1700 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.79 73.0 6.52e-01 100.0% 72.4%
4fzsA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.79 72.0 5.54e-01 100.0% 46.4%
4oydB00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.79 59.0 5.57e-01 78.6% 69.2%
2dq0A01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.79 69.0 6.74e-01 94.9% 86.0%
3vkgA12 1.10.287.2610 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.79 74.0 5.57e-01 100.0% 78.6%
1i4dA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.78 71.0 5.68e-01 100.0% 57.4%
4dciA00 6.10.140.1110 Special › Helix non-globular › Helix Hairpins › 0.78 65.0 5.65e-01 91.8% 59.9%
3qo8A01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.78 65.0 6.35e-01 94.9% 82.1%
2efkA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.77 71.0 5.14e-01 100.0% 38.9%
6xj1A01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.77 67.0 4.95e-01 100.0% 37.6%
3lssA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.77 67.0 6.43e-01 94.9% 81.2%
1qsdA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.77 61.0 6.03e-01 82.7% 79.4%
3u0cA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.77 70.0 5.99e-01 100.0% 63.6%
4q4hA01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.77 65.0 4.46e-01 93.9% 28.0%
3g67A00 1.10.287.950 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein 0.76 70.0 5.38e-01 100.0% 46.9%
4im0A04 1.20.1270.420 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.76 70.0 5.18e-01 100.0% 57.6%
1ydxA02 1.10.287.1120 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein 0.76 63.0 6.57e-01 93.9% 95.6%
1uruA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.76 69.0 5.38e-01 100.0% 67.0%
1vf7A03 1.10.287.470 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.76 47.0 5.66e-01 88.8% 100.0%
3cazB00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.76 69.0 5.28e-01 100.0% 45.7%
2js5A00 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.76 50.0 5.79e-01 82.7% 93.0%
4mh6A00 1.10.287.1700 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.75 69.0 5.84e-01 100.0% 71.7%
4wpcA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.75 68.0 4.86e-01 100.0% 56.5%
7aalA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.75 67.0 4.90e-01 100.0% 48.5%
2b5uA02 1.10.287.620 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix Hairpins 0.74 66.0 5.55e-01 95.9% 77.6%
4wpeA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.74 68.0 4.84e-01 99.0% 65.8%
2ch7A00 1.10.287.950 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein 0.74 67.0 4.64e-01 99.0% 31.1%
1l8dA00 1.10.287.510 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.74 64.0 6.36e-01 95.9% 88.3%
2oexA01 1.20.120.560 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › alix/aip1 in complex with the ypdl late domain 0.73 63.0 5.46e-01 90.8% 65.7%
3vbbE01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.73 65.0 6.03e-01 93.9% 81.5%
1wleA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.73 64.0 6.11e-01 94.9% 87.7%
3ofnY00 1.10.287.80 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain 0.73 59.0 5.58e-01 85.7% 86.1%
2rd0B00 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.73 67.0 5.94e-01 100.0% 86.3%
3fppA03 6.10.140.1990 Special › Helix non-globular › Helix Hairpins › 0.73 60.0 6.26e-01 90.8% 100.0%
1lkoA01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.73 51.0 4.44e-01 72.4% 76.6%
4hr1A00 1.20.1270.410 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.73 50.0 4.72e-01 90.8% 59.3%
6h2dS01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.72 64.0 4.93e-01 99.0% 56.5%
1fpoC02 1.20.1280.20 Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain 0.72 45.0 4.71e-01 88.8% 68.1%
2zdiB00 1.10.287.370 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.72 66.0 6.45e-01 99.0% 91.5%
3c1yA02 1.20.1260.110 Mainly Alpha › Up-down Bundle › Ferritin › DNA integrity scanning linker region 0.72 52.0 4.44e-01 80.6% 49.3%
1wpaA01 6.10.140.340 Special › Helix non-globular › Helix Hairpins › 0.71 58.0 5.78e-01 99.0% 85.9%
2xubA05 6.10.140.1450 Special › Helix non-globular › Helix Hairpins › 0.71 57.0 5.75e-01 84.7% 99.0%
4l8jA04 1.10.287.470 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.71 43.0 5.28e-01 75.5% 100.0%
3zdqA01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.70 61.0 4.24e-01 99.0% 28.5%
1jadA00 1.20.1230.10 Mainly Alpha › Up-down Bundle › Phospholipase C Beta; Chain: A › Phospholipase C beta, distal C-terminal domain 0.70 62.0 4.67e-01 99.0% 66.9%
3s84A02 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.69 61.0 5.27e-01 99.0% 63.1%
2gl2B00 1.10.287.1700 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.69 57.0 5.54e-01 88.8% 81.7%
3syvA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.69 61.0 4.60e-01 100.0% 42.4%
6q45G01 1.10.287.80 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain 0.68 54.0 4.77e-01 85.7% 88.4%
4mrsA01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.68 60.0 4.13e-01 99.0% 27.8%
3o6xA02 1.20.120.1560 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.67 60.0 5.25e-01 100.0% 71.6%
7zd5C01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.66 59.0 4.14e-01 100.0% 31.5%
2ozbB01 1.10.287.4070 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.60 54.0 4.83e-01 95.9% 93.1%
2bg9C02 1.20.58.390 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Neurotransmitter-gated ion-channel transmembrane domain 0.57 51.0 4.35e-01 100.0% 88.1%
ECOD (84)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3620978 2003.1.2.18 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain 0.85 78.0 5.26e-01 100.0% 29.7%
5019536 3755.1.1.0 alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related 0.84 78.0 5.83e-01 100.0% 45.3%
3385717 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.84 78.0 6.39e-01 100.0% 67.6%
1759951 5086.1.1.88 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_CyaD 0.83 78.0 6.12e-01 100.0% 52.6%
3973283 325.1.7.27 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › HH_AprE 0.83 77.0 6.03e-01 100.0% 63.1%
3481541 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.82 70.0 6.99e-01 88.8% 94.0%
3935064 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.82 77.0 5.31e-01 100.0% 34.6%
3920552 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.82 77.0 5.82e-01 100.0% 47.1%
3241030 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.81 74.0 5.04e-01 100.0% 30.2%
4982830 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.81 69.0 5.71e-01 88.8% 76.2%
3584480 3835.1.1.0 alpha bundles › Type I hyperactive antifreeze protein › Type I hyperactive antifreeze protein › Type I hyperactive antifreeze protein 0.81 75.0 6.15e-01 100.0% 82.4%
3294656 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.81 77.0 5.00e-01 100.0% 27.3%
3808040 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.81 76.0 6.04e-01 100.0% 54.1%
3273923 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.81 76.0 4.86e-01 100.0% 32.5%
5070735 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.81 72.0 5.75e-01 92.9% 52.6%
5039743 3755.3.1.637 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DUF7121 0.81 75.0 6.21e-01 100.0% 100.0%
4076629 220.1.1.22 beta barrels › PH domain-like › PH domain-like › PH domain-like › FERM_C 0.81 75.0 5.31e-01 100.0% 48.7%
4932148 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.80 68.0 6.25e-01 100.0% 71.2%
3975632 5086.1.1.92 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_AprE 0.80 75.0 5.94e-01 100.0% 55.1%
5069236 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.80 75.0 6.05e-01 100.0% 57.1%
3876986 3291.1.1.84 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › PF28341 0.80 74.0 5.88e-01 100.0% 53.3%
3594185 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.80 74.0 5.71e-01 100.0% 48.8%
4237056 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.80 66.0 5.83e-01 88.8% 70.7%
3235307 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.80 74.0 4.93e-01 100.0% 79.1%
3962991 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.80 74.0 5.80e-01 100.0% 56.4%
3534459 4177.1.1.1 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH 0.79 70.0 5.02e-01 100.0% 35.1%
3838987 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.79 74.0 5.74e-01 100.0% 53.0%
98832 2003.1.2.18 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain 0.79 73.0 4.81e-01 100.0% 28.4%
3819327 3758.1.1.31 alpha bundles › Bacterial hemolysins-like › Bacterial hemolysins › Bacterial hemolysins › DUF677 0.79 72.0 5.05e-01 100.0% 34.0%
3235839 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.79 73.0 5.91e-01 100.0% 65.7%
3704105 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.79 74.0 6.14e-01 100.0% 80.0%
4321938 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.79 73.0 6.03e-01 100.0% 95.8%
5060432 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.79 69.0 6.22e-01 92.9% 84.6%
3470751 3755.3.1.297 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › KIF9 0.78 73.0 6.05e-01 99.0% 62.5%
5083949 5086.1.1.84 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_MFP_RND 0.78 73.0 6.58e-01 100.0% 88.5%
3586751 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.78 72.0 5.80e-01 100.0% 71.1%
3875112 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.78 72.0 4.85e-01 100.0% 44.7%
3702347 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.78 73.0 5.89e-01 100.0% 60.6%
4193109 2004.1.1.429 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_15 0.78 71.0 4.06e-01 100.0% 15.8%
1313624 5086.1.1.92 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_AprE 0.78 73.0 5.99e-01 100.0% 61.1%
4588350 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.78 65.0 5.57e-01 88.8% 66.0%
5070736 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.78 68.0 5.23e-01 91.8% 46.0%
4001189 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.78 73.0 4.58e-01 100.0% 22.0%
4086306 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.78 73.0 5.42e-01 100.0% 44.0%
3964486 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.77 72.0 6.03e-01 100.0% 63.7%
3251434 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.77 72.0 5.79e-01 100.0% 70.6%
3779599 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.77 72.0 4.51e-01 99.0% 95.7%
4175809 5086.1.1.88 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_CyaD 0.77 68.0 5.69e-01 99.0% 57.0%
4392204 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.77 71.0 5.36e-01 100.0% 48.6%
5005097 3710.1.1.0 alpha bundles › Golgi to ER traffic protein 1 cytosolic domain › Golgi to ER traffic protein 1 cytosolic domain › Golgi to ER traffic protein 1 cytosolic domain 0.77 71.0 6.35e-01 100.0% 81.2%
3952630 3755.1.1.0 alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related 0.77 67.0 5.93e-01 100.0% 66.4%
5056871 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.77 71.0 4.88e-01 100.0% 90.3%
5082020 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.76 71.0 4.72e-01 100.0% 79.4%
3398185 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.76 69.0 5.71e-01 95.9% 60.0%
3609437 632.22.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.76 70.0 6.26e-01 100.0% 74.1%
4210642 3755.1.1.12 alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related › CheZ 0.75 69.0 6.27e-01 100.0% 83.1%
3661101 3755.3.1.290 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › PPI_helical 0.75 70.0 5.91e-01 100.0% 81.9%
3594129 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.75 70.0 5.31e-01 100.0% 46.0%
1097271 3755.1.1.1 alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related › YscO 0.75 69.0 5.98e-01 100.0% 75.7%
3522868 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.75 70.0 6.62e-01 100.0% 90.4%
3967398 3755.1.1.1 alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related › YscO 0.75 68.0 5.88e-01 100.0% 66.0%
3579748 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.75 70.0 5.70e-01 100.0% 71.2%
4097174 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.75 66.0 3.97e-01 94.9% 69.9%
3560229 3291.1.1.230 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › TBCA_PH 0.74 67.0 5.95e-01 100.0% 72.9%
3386973 5086.1.1.84 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_MFP_RND 0.74 61.0 6.39e-01 88.8% 97.8%
3936511 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.74 67.0 4.32e-01 100.0% 86.2%
4991905 3684.1.1.0 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.74 67.0 4.77e-01 100.0% 50.2%
5049284 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.74 67.0 6.24e-01 100.0% 90.8%
4549103 3755.4.1.54 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › PF30340 0.74 66.0 4.43e-01 100.0% 100.0%
3169381 874.1.1.0 a+b duplicates or obligate multimers › Smc hinge domain › Smc hinge domain › Smc hinge domain 0.74 66.0 5.21e-01 100.0% 54.1%
3970271 3755.1.1.8 alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related › FliJ 0.73 64.0 5.93e-01 95.9% 76.0%
3503238 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.73 62.0 5.03e-01 88.8% 51.2%
3167364 2004.1.1.481 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_29 0.73 68.0 4.35e-01 99.0% 27.1%
3977409 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.73 68.0 6.04e-01 100.0% 83.7%
3305747 192.2.1.18 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › ING 0.73 68.0 5.95e-01 100.0% 70.7%
3978264 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.73 64.0 5.55e-01 96.9% 94.0%
5070649 2004.1.1.87 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N 0.71 64.0 3.81e-01 100.0% 15.4%
3422920 1075.4.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane 0.71 60.0 4.55e-01 100.0% 38.7%
4395939 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.69 63.0 4.63e-01 100.0% 48.2%
3694833 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.68 60.0 5.45e-01 95.9% 71.5%
3592587 3567.1.1.0 a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer 0.68 58.0 5.41e-01 99.0% 73.6%
4045132 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.66 59.0 5.74e-01 100.0% 91.8%
3600869 3567.1.1.0 a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer 0.65 56.0 5.34e-01 95.9% 84.3%
3182497 2004.1.1.87 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N 0.62 55.0 3.61e-01 100.0% 51.6%
D2 medium residues 229-342
PDB
Domain cluster: representative
CATH (38)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2fcwA00 1.20.81.10 Mainly Alpha › Up-down Bundle › Receptor-associated Protein › RAP domain 0.83 40.0 4.19e-01 95.6% 50.9%
1sumB01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.77 52.0 5.43e-01 70.2% 99.1%
3nvoB02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.75 52.0 5.19e-01 71.1% 96.6%
3ck6C02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.74 52.0 5.16e-01 71.9% 93.3%
1t98A02 1.20.58.590 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Chromosome partition protein MukF, middle domain 0.72 50.0 4.41e-01 71.1% 79.1%
2w2dD01 1.20.1120.10 Mainly Alpha › Up-down Bundle › "Clostridium botulinum neurotoxin B, ""coiled-coil"" domain" › "Clostridium botulinum neurotoxin b, ""coiled-coil"" domain" 0.71 49.0 3.30e-01 70.2% 46.2%
2yfaA02 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.70 58.0 5.77e-01 86.0% 93.1%
1yo7A00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.70 57.0 5.62e-01 86.0% 91.7%
5nl6B01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.67 46.0 4.57e-01 70.2% 95.9%
4yjwA00 1.20.120.930 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein PF12889, N-terminal DUF3829 0.65 45.0 4.05e-01 71.1% 65.4%
1yt3A02 1.10.150.80 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › HRDC domain 0.63 44.0 4.67e-01 81.6% 82.8%
2rgnB01 1.20.900.10 Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain 0.62 51.0 4.22e-01 89.5% 73.0%
7z7vF03 1.20.1440.230 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain 0.61 45.0 4.95e-01 77.2% 98.9%
4al0A00 1.20.120.550 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Membrane associated eicosanoid/glutathione metabolism-like domain 0.59 44.0 4.08e-01 78.1% 88.4%
7y9hB01 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.59 51.0 3.75e-01 96.5% 47.5%
7w5gA01 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.58 50.0 3.59e-01 95.6% 52.3%
3rkgA02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.58 53.0 4.70e-01 100.0% 90.9%
2v0oB00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.56 39.0 2.95e-01 90.4% 30.3%
3o10C00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.56 39.0 3.65e-01 90.4% 58.8%
2ot4A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.56 38.0 3.97e-01 70.2% 92.5%
2dwkA00 1.20.58.900 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › RUN domain 0.56 41.0 3.75e-01 79.8% 73.9%
1wwmA00 1.20.910.10 Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like 0.55 47.0 4.10e-01 94.7% 70.0%
7dl9A01 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.54 43.0 3.67e-01 86.0% 90.2%
7zxkC01 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.54 43.0 3.99e-01 86.0% 74.7%
2x0cA01 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.54 48.0 4.09e-01 98.2% 61.2%
4alyB00 1.10.3160.10 Mainly Alpha › Orthogonal Bundle › Bbcrasp-1 › Bbcrasp-1 0.53 40.0 3.42e-01 78.9% 70.1%
1qv9A02 6.10.140.120 Special › Helix non-globular › Helix Hairpins › 0.53 42.0 4.46e-01 97.4% 94.2%
1eqfA02 1.20.920.10 Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like 0.53 43.0 4.25e-01 88.6% 83.2%
1grlB01 1.10.560.10 Mainly Alpha › Orthogonal Bundle › GROEL; domain 1 › GroEL-like equatorial domain 0.52 43.0 3.50e-01 93.9% 58.2%
7zcvA02 1.25.40.400 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.52 44.0 3.63e-01 93.0% 64.8%
3h4cA02 1.10.472.110 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › 0.52 38.0 3.87e-01 76.3% 90.9%
3crjC00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.52 46.0 3.95e-01 96.5% 70.9%
3ubcA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.51 38.0 3.63e-01 75.4% 93.1%
3pltA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.51 46.0 3.74e-01 100.0% 76.6%
1avoB00 1.20.120.180 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Proteasome activator pa28, C-terminal domain 0.51 46.0 4.34e-01 100.0% 91.4%
5f2kB01 1.10.1200.270 Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › Methyltransferase, alpha-helical capping domain 0.51 38.0 3.61e-01 80.7% 79.6%
3p4tA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.50 40.0 3.65e-01 85.1% 82.7%
2zs0A00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.50 37.0 3.47e-01 76.3% 95.7%
ECOD (38)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3441289 3684.1.1.19 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › DUF1110 0.81 43.0 3.66e-01 90.4% 34.3%
3919843 604.1.1.124 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin_6 0.75 52.0 4.98e-01 71.1% 95.4%
4663621 603.2.1.0 alpha bundles › STAT-like › STAT › STAT 0.72 50.0 4.80e-01 71.1% 96.9%
2325490 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.70 48.0 4.91e-01 71.1% 93.8%
3527488 604.5.1.0 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) 0.69 54.0 4.54e-01 83.3% 98.9%
4018811 603.1.1.158 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › KAR9 0.68 46.0 4.47e-01 70.2% 86.2%
4261817 5086.1.1.91 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › PRM1 0.67 57.0 4.81e-01 92.1% 82.5%
3257419 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.67 54.0 5.38e-01 86.8% 89.2%
3752375 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.65 55.0 4.57e-01 90.4% 96.9%
3932144 633.4.1.0 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor 0.65 48.0 4.79e-01 76.3% 98.3%
3359764 3930.1.1.0 alpha bundles › Helical bundle insertion in helicase domains › Helical bundle in Hef helicase › Helical bundle in Hef helicase 0.65 54.0 5.31e-01 90.4% 88.8%
3703280 5069.1.1.7 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cytochrom_B561 0.65 52.0 4.22e-01 85.1% 96.2%
3393880 633.11.1.1 alpha bundles › Bromodomain-like › Nqo1C-terminal domain-like › Nqo1C-terminal domain-like › NADH_4Fe-4S 0.65 49.0 5.33e-01 82.5% 96.8%
3503307 1203.1.2.1 alpha bundles › Shroom domain 2 › Shroom domain 2 › Human SD2 › ASD2 0.64 52.0 4.65e-01 87.7% 95.6%
3469833 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.64 44.0 4.33e-01 70.2% 90.0%
3963163 601.1.2.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) 0.59 49.0 4.49e-01 92.1% 96.8%
3853109 5001.1.1.138 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › PF30689 0.57 52.0 3.74e-01 100.0% 50.2%
4027714 592.2.1.2 alpha arrays › PWI domain-like › YugE-like › YugE-like › WGG 0.57 44.0 4.45e-01 82.5% 88.2%
4964257 2004.1.1.173 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › TrwB_AAD_bind 0.57 48.0 3.27e-01 93.0% 43.5%
3861499 189.1.1.2 alpha bundles › GTPase activation domain, GAP › GTPase activation domain, GAP › GTPase activation domain, GAP › RhoGAP 0.57 47.0 3.32e-01 89.5% 67.1%
3721200 611.9.1.5 alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › SesA 0.56 39.0 3.83e-01 72.8% 96.9%
3282593 4121.1.1.1 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › CorA 0.56 50.0 3.97e-01 100.0% 92.1%
3217668 6055.1.1.33 extended segments › Preprotein translocase subunit YajC › Preprotein translocase subunit YajC › Preprotein translocase subunit YajC › 7TM_GPCR_Srz 0.55 53.0 4.46e-01 100.0% 66.3%
3268501 141.1.1.3 alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › UbiA 0.55 48.0 3.58e-01 95.6% 66.4%
3287060 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.54 43.0 3.42e-01 87.7% 85.0%
4259041 150.3.1.1 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › 4-helical cytokines › 4-helical cytokine › Hormone_1 0.53 42.0 3.58e-01 86.0% 57.9%
3933311 5001.1.1.32 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Solute_trans_a 0.53 40.0 3.13e-01 78.9% 83.3%
3859783 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.53 45.0 3.31e-01 93.0% 83.5%
3294130 5053.1.1.1 alpha complex topology › Clc chloride channel › Clc chloride channel › Clc chloride channel › Voltage_CLC 0.52 44.0 3.12e-01 94.7% 33.9%
4050465 109.4.1.340 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › BP28CT 0.52 44.0 2.83e-01 89.5% 20.0%
3977220 4121.1.1.1 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › CorA 0.52 47.0 3.60e-01 100.0% 53.8%
3961583 141.1.1.3 alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › UbiA 0.52 45.0 3.85e-01 98.2% 95.9%
3804981 192.29.1.7 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › TMEM192 0.52 45.0 4.03e-01 100.0% 69.0%
3603733 4121.1.1.19 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › PF27230 0.52 46.0 3.37e-01 100.0% 91.3%
4980755 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.51 47.0 4.40e-01 100.0% 81.4%
4988447 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.51 46.0 4.62e-01 100.0% 95.7%
4014198 611.9.1.0 alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain 0.51 40.0 3.86e-01 86.0% 100.0%
3507161 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.50 43.0 3.12e-01 100.0% 34.1%
D3 medium residues 400-444
PDB
Domain cluster: representative
CATH (66)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4kyzA00 3.30.70.600 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10 0.82 69.0 4.67e-01 97.8% 47.3%
1nh8A03 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.79 67.0 5.97e-01 100.0% 100.0%
2hvzA01 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.75 61.0 5.29e-01 93.3% 100.0%
6s2wA01 3.30.2260.10 Alpha Beta › 2-Layer Sandwich › ERH-like fold › Enhancer of rudimentary 0.75 63.0 5.19e-01 95.6% 68.3%
7ejoB01 3.30.2260.10 Alpha Beta › 2-Layer Sandwich › ERH-like fold › Enhancer of rudimentary 0.74 62.0 5.11e-01 95.6% 72.3%
2cfmA02 3.30.470.30 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme 0.70 58.0 3.85e-01 100.0% 81.1%
3egrA00 3.10.20.520 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phenylacetic acid degradation B 0.68 56.0 5.12e-01 97.8% 77.8%
1qysA00 3.30.1710.10 Alpha Beta › 2-Layer Sandwich › top7, de novo designed protein › top7, de novo designed protein 0.68 54.0 4.51e-01 97.8% 56.5%
5cadA01 2.60.120.10 Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls 0.67 49.0 3.27e-01 100.0% 18.7%
2byeA01 3.10.20.90 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 0.67 56.0 4.45e-01 100.0% 50.5%
2kgfA00 1.10.375.10 Mainly Alpha › Orthogonal Bundle › Human Immunodeficiency Virus Type 1 Capsid Protein › Human Immunodeficiency Virus Type 1 Capsid Protein 0.67 48.0 3.53e-01 82.2% 47.9%
3mdnD00 3.60.20.10 Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Aminohydrolase, N-terminal nucleophile (Ntn) domain 0.66 53.0 3.45e-01 95.6% 19.3%
4llgM00 3.10.20.510 Alpha Beta › Roll › Ubiquitin-like (UB roll) › RNA polymerase inhibitor 0.66 54.0 5.35e-01 100.0% 90.0%
2dm4A01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.66 54.0 4.31e-01 100.0% 44.7%
3lqmA02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.66 53.0 4.17e-01 100.0% 41.2%
2q9kA00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.65 54.0 3.89e-01 100.0% 37.4%
2b39A10 2.60.120.1540 Mainly Beta › Sandwich › Jelly Rolls › 0.65 55.0 4.14e-01 100.0% 56.9%
5l10B00 3.30.450.80 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › Transcription factor LuxR-like, autoinducer-binding domain 0.64 47.0 3.26e-01 82.2% 94.1%
2jvfA00 3.30.1710.10 Alpha Beta › 2-Layer Sandwich › top7, de novo designed protein › top7, de novo designed protein 0.64 51.0 4.25e-01 100.0% 57.4%
2q0oA01 3.30.450.80 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › Transcription factor LuxR-like, autoinducer-binding domain 0.64 47.0 3.24e-01 82.2% 94.6%
5of3A00 3.90.920.10 Alpha Beta › Alpha-Beta Complex › DNA primase, PRIM domain › DNA primase, PRIM domain 0.64 53.0 3.23e-01 100.0% 14.4%
3nd1A02 3.30.950.10 Alpha Beta › 2-Layer Sandwich › Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 › Tetrapyrrole methylase, C-terminal domain 0.64 55.0 4.18e-01 100.0% 41.8%
2aehA01 3.10.20.90 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 0.63 50.0 4.05e-01 100.0% 43.8%
4gs7C02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.63 51.0 4.09e-01 100.0% 43.9%
3bn6A00 2.60.120.260 Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like 0.63 52.0 3.64e-01 97.8% 55.7%
2pn5A08 2.60.120.1540 Mainly Beta › Sandwich › Jelly Rolls › 0.63 52.0 4.00e-01 97.8% 55.9%
3nngA00 2.60.120.260 Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like 0.61 51.0 3.59e-01 97.8% 55.6%
1l3lA01 3.30.450.80 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › Transcription factor LuxR-like, autoinducer-binding domain 0.61 46.0 3.16e-01 84.4% 94.7%
2vugA02 3.30.1490.70 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › 0.61 49.0 4.33e-01 97.8% 59.7%
3ffyA00 3.30.950.10 Alpha Beta › 2-Layer Sandwich › Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 › Tetrapyrrole methylase, C-terminal domain 0.61 51.0 3.91e-01 100.0% 67.0%
1x5fA00 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.60 52.0 3.87e-01 100.0% 37.5%
1n26A03 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.60 48.0 3.83e-01 97.8% 41.3%
2o6cA00 2.60.40.2480 Mainly Beta › Sandwich › Immunoglobulin-like › Periplasmic metal-binding protein Tp34-type 0.60 52.0 3.62e-01 100.0% 31.6%
3pvlA02 3.10.20.90 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 0.60 49.0 3.99e-01 100.0% 69.8%
3zq5A03 3.30.450.270 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PHY domain 0.60 43.0 2.97e-01 75.6% 41.8%
6uqjA02 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.60 47.0 2.87e-01 93.3% 28.7%
2xqyA03 2.60.40.3190 Mainly Beta › Sandwich › Immunoglobulin-like › Herpesvirus glycoprotein H, C-terminal domain 0.59 50.0 3.71e-01 100.0% 37.6%
4lsdF00 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.59 50.0 4.00e-01 100.0% 45.9%
5e55B02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.59 50.0 4.06e-01 100.0% 50.5%
3cjlA00 3.10.20.850 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Protein of unknown function DUF3861 0.59 41.0 3.31e-01 73.3% 63.6%
3hrzC01 2.20.210.20 Mainly Beta › Single Sheet › ubp-family deubiquitinating enzyme fold › 0.59 51.0 5.02e-01 100.0% 91.8%
4msvA01 2.60.120.40 Mainly Beta › Sandwich › Jelly Rolls › 0.58 47.0 3.52e-01 100.0% 65.7%
1sq2N00 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.58 48.0 3.71e-01 97.8% 47.3%
1bquA02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.58 48.0 3.77e-01 100.0% 43.5%
3d4rE01 2.40.128.400 Mainly Beta › Beta Barrel › Lipocalin › 0.58 38.0 3.26e-01 97.8% 36.9%
2vtfA02 2.60.120.260 Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like 0.57 47.0 3.29e-01 100.0% 34.5%
1zvfB01 2.60.120.10 Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls 0.56 43.0 3.06e-01 88.9% 32.3%
2jxtA01 3.10.20.10 Alpha Beta › Roll › Ubiquitin-like (UB roll) › 0.56 42.0 3.86e-01 100.0% 71.1%
1e25A00 3.40.710.10 Alpha Beta › 3-Layer(aba) Sandwich › Beta-lactamase › DD-peptidase/beta-lactamase superfamily 0.55 44.0 2.84e-01 100.0% 74.5%
4lr4A02 2.60.120.1430 Mainly Beta › Sandwich › Jelly Rolls › 0.55 45.0 3.16e-01 100.0% 28.6%
2dn7A00 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.54 43.0 3.48e-01 100.0% 42.1%
6l4lA01 3.10.310.10 Alpha Beta › Roll › Diaminopimelate Epimerase; Chain A, domain 1 › Diaminopimelate Epimerase; Chain A, domain 1 0.54 46.0 3.50e-01 100.0% 98.3%
1sazA02 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.54 40.0 2.78e-01 86.7% 77.7%
8os3A01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.54 43.0 3.61e-01 100.0% 50.0%
3kyfA01 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.54 45.0 3.45e-01 100.0% 49.1%
3lb6D02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.53 42.0 3.51e-01 97.8% 53.3%
3s7iB01 2.60.120.10 Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls 0.53 42.0 2.95e-01 100.0% 65.9%
4dxzA00 2.60.120.380 Mainly Beta › Sandwich › Jelly Rolls › 0.53 37.0 2.92e-01 82.2% 31.5%
1xreA02 3.55.40.20 Alpha Beta › 3-Layer(bab) Sandwich › minor pseudopilin epsh fold › Iron/manganese superoxide dismutase, C-terminal domain 0.53 38.0 3.06e-01 100.0% 34.8%
1cauA00 2.60.120.10 Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls 0.52 42.0 2.95e-01 100.0% 69.6%
4bwsF00 3.30.1490.40 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › GYF domain 0.52 42.0 3.84e-01 100.0% 67.2%
4x83A03 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.52 40.0 3.22e-01 91.1% 43.1%
1s4dE02 3.30.950.10 Alpha Beta › 2-Layer Sandwich › Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 › Tetrapyrrole methylase, C-terminal domain 0.52 42.0 3.11e-01 100.0% 56.1%
3snoA01 3.30.470.10 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › Aminotransferase class 4, branched-chain amino acid transferase, N-terminal domain 0.52 42.0 3.22e-01 100.0% 97.5%
4e6xB00 3.40.710.10 Alpha Beta › 3-Layer(aba) Sandwich › Beta-lactamase › DD-peptidase/beta-lactamase superfamily 0.51 42.0 2.62e-01 100.0% 67.8%
3su0A01 2.40.10.120 Mainly Beta › Beta Barrel › Thrombin, subunit H › 0.50 38.0 3.08e-01 95.6% 40.2%
ECOD (72)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4147528 4.1.1.307 beta barrels › SH3 › SH3 › SH3 › PF26132 0.84 75.0 6.36e-01 97.8% 100.0%
4448678 4.1.1.307 beta barrels › SH3 › SH3 › SH3 › PF26132 0.83 73.0 6.10e-01 97.8% 96.0%
4231372 4.1.1.307 beta barrels › SH3 › SH3 › SH3 › PF26132 0.82 71.0 6.15e-01 97.8% 98.6%
3705856 4121.1.1.1 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › CorA 0.79 69.0 4.14e-01 100.0% 15.0%
3672250 207.1.1.116 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › LRR_FBXL15 0.78 65.0 4.31e-01 100.0% 23.2%
3282305 4187.1.1.0 a+b two layers › NosL/MerB-like › NosL/MerB-like › NosL/MerB-like 0.75 66.0 5.72e-01 100.0% 65.7%
5031580 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.73 60.0 3.99e-01 100.0% 81.5%
3911249 221.1.1.76 a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › RA_2 0.72 57.0 4.49e-01 100.0% 42.1%
3959440 4.1.1.180 beta barrels › SH3 › SH3 › SH3 › DUF3107 0.72 59.0 5.33e-01 95.6% 98.5%
3405569 221.1.1.6 a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › RA 0.71 56.0 4.24e-01 100.0% 36.4%
3231713 221.1.1.0 a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like 0.71 55.0 4.47e-01 100.0% 44.4%
3476439 382.1.1.0 few secondary structure elements › Snake toxin-like › Snake toxin-like › Snake toxin-like 0.70 57.0 4.83e-01 100.0% 54.7%
3211869 221.1.1.0 a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like 0.70 56.0 4.51e-01 100.0% 45.6%
3177995 5050.1.1.32 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Acatn 0.69 52.0 2.96e-01 100.0% 7.2%
3386935 2484.1.1.53 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › MreB_Mbl 0.69 50.0 3.47e-01 75.6% 87.3%
3601705 4121.1.1.0 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like 0.69 59.0 3.54e-01 100.0% 13.4%
3735748 821.1.1.3 a+b three layers › GIY-YIG endonuclease › GIY-YIG endonuclease › GIY-YIG endonuclease › T5orf172 0.68 58.0 3.95e-01 100.0% 27.1%
3400462 379.1.1.0 few secondary structure elements › Kazal-type serine protease inhibitors-like › Kazal-type serine protease inhibitors › Kazal-type serine protease inhibitors 0.67 53.0 4.95e-01 100.0% 70.7%
3590261 822.3.1.1 a+b two layers › GYF/BRK domain-like › conserved domain protein SP_1775 › conserved domain protein SP_1775 › DUF4649 0.67 56.0 4.95e-01 97.8% 69.1%
2126757 170.2.1.1 alpha bundles › Retrovirus capsid protein › Retrovirus capsid protein N-terminal domain › Retrovirus capsid protein N-terminal domain › Gag_p24 0.67 48.0 3.53e-01 82.2% 47.9%
3959955 304.163.1.3 a+b two layers › Alpha-beta plaits › ATP-binding protein TM_1403 insertion domain › ATP-binding protein TM_1403 insertion domain › PF31118 0.65 52.0 5.24e-01 97.8% 95.6%
3859590 386.1.1.248 few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › zf-C2H2_ZNF592 0.65 53.0 5.17e-01 100.0% 86.0%
4959407 304.163.1.3 a+b two layers › Alpha-beta plaits › ATP-binding protein TM_1403 insertion domain › ATP-binding protein TM_1403 insertion domain › PF31118 0.65 53.0 5.18e-01 100.0% 86.0%
5027350 301.1.1.2 a+b three layers › Bacillus chorismate mutase-like › L30e-like › L30e-like › eRF1_3 0.65 54.0 3.91e-01 100.0% 51.4%
3302660 109.4.1.1256 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, PPR_3 0.64 54.0 3.51e-01 100.0% 24.1%
3429551 109.4.1.1285 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, DYW_deaminase, Eplus_motif, E_motif 0.63 48.0 2.78e-01 82.2% 21.7%
4995671 3115.1.1.12 a+b two layers › GP2-like › RplX-like › RplX-like › PF30567 0.63 51.0 5.02e-01 100.0% 88.0%
3782773 822.1.1.1 a+b two layers › GYF/BRK domain-like › GYF domain › GYF domain › GYF 0.63 49.0 4.74e-01 100.0% 76.4%
3586250 822.1.1.1 a+b two layers › GYF/BRK domain-like › GYF domain › GYF domain › GYF 0.63 49.0 4.59e-01 100.0% 68.3%
4038221 862.1.1.1 a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain › DNA_primase_S 0.63 53.0 3.41e-01 100.0% 77.5%
3378740 109.4.1.1291 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, PPR_3, DYW_deaminase, E_motif 0.62 55.0 2.97e-01 100.0% 7.0%
3385387 109.4.1.1521 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, DYW_deaminase, Eplus_motif, E_motif 0.62 55.0 3.06e-01 100.0% 11.1%
3834151 109.4.1.3495 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, PPR_3, DYW_deaminase, PPR_long, E_motif, TPR_24 0.62 55.0 3.07e-01 100.0% 11.9%
3701633 221.1.1.0 a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like 0.62 47.0 3.99e-01 97.8% 47.1%
5014684 3115.1.1.0 a+b two layers › GP2-like › RplX-like › RplX-like 0.62 51.0 4.79e-01 100.0% 82.8%
3683687 109.4.1.1267 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, DYW_deaminase, E_motif 0.62 55.0 3.02e-01 100.0% 10.2%
3311892 109.4.1.1267 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, DYW_deaminase, E_motif 0.62 55.0 3.16e-01 100.0% 15.7%
3657071 109.4.1.2208 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, DYW_deaminase, Eplus_motif, E_motif, TPR_24 0.62 55.0 3.14e-01 100.0% 15.6%
3802249 109.4.1.1291 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, PPR_3, DYW_deaminase, E_motif 0.62 55.0 3.05e-01 100.0% 11.7%
3483429 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.62 50.0 3.64e-01 97.8% 58.6%
3348902 109.4.1.1291 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, PPR_3, DYW_deaminase, E_motif 0.61 54.0 3.02e-01 100.0% 11.2%
3817532 109.4.1.2179 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_3, DYW_deaminase, E_motif 0.61 54.0 2.99e-01 100.0% 10.3%
4982033 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.61 49.0 3.80e-01 100.0% 39.1%
3681440 109.4.1.1267 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, DYW_deaminase, E_motif 0.61 53.0 2.98e-01 100.0% 11.7%
3825377 109.4.1.1291 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, PPR_3, DYW_deaminase, E_motif 0.61 53.0 2.92e-01 100.0% 9.6%
3751173 4357.1.1.0 beta barrels › WWE domain › WWE domain › WWE domain 0.60 48.0 4.25e-01 97.8% 98.7%
3501103 822.1.1.1 a+b two layers › GYF/BRK domain-like › GYF domain › GYF domain › GYF 0.59 46.0 4.22e-01 100.0% 65.1%
3929515 382.1.1.21 few secondary structure elements › Snake toxin-like › Snake toxin-like › Snake toxin-like › PF28966 0.59 49.0 3.85e-01 100.0% 61.9%
3649276 887.1.1.0 a+b two layers › Ribosomal protein L30p/L7e › Ribosomal protein L30p/L7e › Ribosomal protein L30p/L7e 0.59 44.0 3.48e-01 100.0% 35.0%
5001166 301.1.1.2 a+b three layers › Bacillus chorismate mutase-like › L30e-like › L30e-like › eRF1_3 0.59 45.0 3.44e-01 100.0% 32.6%
3542679 11.2.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain 0.59 43.0 3.16e-01 82.2% 62.2%
3968768 3115.1.1.0 a+b two layers › GP2-like › RplX-like › RplX-like 0.58 45.0 4.07e-01 100.0% 100.0%
3333061 109.4.1.1267 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, DYW_deaminase, E_motif 0.58 49.0 2.75e-01 100.0% 10.5%
3390562 382.1.1.0 few secondary structure elements › Snake toxin-like › Snake toxin-like › Snake toxin-like 0.58 44.0 4.04e-01 95.6% 67.1%
3704468 221.1.1.0 a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like 0.57 47.0 3.60e-01 93.3% 86.4%
4463006 3115.2.1.0 a+b two layers › GP2-like › GP2 › GP2 0.57 44.0 4.42e-01 97.8% 95.6%
3407846 221.1.1.76 a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › RA_2 0.57 44.0 3.54e-01 91.1% 90.0%
3311693 1.1.7.0 beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C 0.57 46.0 3.70e-01 100.0% 61.0%
5081134 3986.2.1.0 a+b two layers › GTP-binding protein lepA C-terminal domain-like › Antitoxin Dmd › Antitoxin Dmd 0.57 46.0 4.29e-01 97.8% 85.0%
5038375 4081.1.1.2 beta sandwiches › Baculovirus p35 protein-related › Baculovirus p35 protein-related › Baculovirus p35 protein-related › VIT 0.56 48.0 3.20e-01 100.0% 51.0%
5053078 304.20.1.4 a+b two layers › Alpha-beta plaits › PAP/Archaeal CCA-adding enzyme, C-terminal domain › PAP/Archaeal CCA-adding enzyme, C-terminal domain › CAA_C 0.56 38.0 2.71e-01 75.6% 31.4%
4143836 4954.1.1.1 a+b complex topology › central helical domain in RNA-polymerase beta-prime subunit › central helical domain in RNA-polymerase beta-prime subunit › central helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_5 0.56 47.0 2.93e-01 100.0% 16.1%
3434515 109.4.1.2925 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, DYW_deaminase, PPR_long, E_motif 0.55 48.0 2.62e-01 100.0% 9.3%
5080205 3115.1.1.0 a+b two layers › GP2-like › RplX-like › RplX-like 0.54 41.0 4.09e-01 100.0% 96.0%
3513507 7508.1.1.1 a/b three-layered sandwiches › O-glucosyltransferase rumi N-terminal domain › O-glucosyltransferase rumi N-terminal domain › O-glucosyltransferase rumi N-terminal domain › Glyco_transf_90 0.54 40.0 2.87e-01 80.0% 69.6%
5050481 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.53 40.0 2.91e-01 82.2% 94.2%
3438348 221.1.1.0 a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like 0.52 40.0 3.45e-01 86.7% 86.7%
1566283 560.1.1.2 few secondary structure elements › H-NS histone-like proteins, C-terminal domain › H-NS histone-like proteins, C-terminal domain › H-NS histone-like proteins, C-terminal domain › MvaT_DBD 0.52 45.0 4.51e-01 100.0% 97.9%
4999557 247.1.1.1 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B 0.52 40.0 2.55e-01 100.0% 32.5%
3347090 221.1.1.159 a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › DUF7138 0.52 39.0 3.50e-01 100.0% 83.5%
3890322 389.1.1.0 few secondary structure elements › EGF-like › EGF-related › EGF/Laminin 0.51 40.0 2.68e-01 97.8% 20.8%
3646939 10.32.1.212 beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like › GUB_WAK_bind 0.51 40.0 2.79e-01 100.0% 30.3%
D4 medium residues 453-511
PDB
Domain cluster: representative
CATH (58)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1wpaA01 6.10.140.340 Special › Helix non-globular › Helix Hairpins › 0.96 70.0 5.70e-01 76.3% 47.5%
3fxdB00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.95 64.0 6.47e-01 76.3% 70.7%
3u0cA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.93 68.0 4.85e-01 76.3% 29.8%
3tklB01 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.92 71.0 6.96e-01 79.7% 98.4%
3sfvB02 6.10.140.2010 Special › Helix non-globular › Helix Hairpins › 0.91 67.0 4.44e-01 76.3% 22.5%
1x4tA01 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.90 65.0 6.55e-01 74.6% 100.0%
3kr9A02 1.10.287.1890 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.90 73.0 7.25e-01 86.4% 98.4%
4gouA03 1.20.900.10 Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain 0.90 72.0 4.82e-01 84.7% 54.3%
2wmmA01 1.20.5.420 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C 0.90 64.0 7.03e-01 74.6% 98.0%
3m7gA02 1.10.8.1010 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.89 63.0 5.30e-01 76.3% 46.3%
2p4vA01 1.10.287.180 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Transcription elongation factor, GreA/GreB, N-terminal domain 0.88 66.0 6.02e-01 79.7% 71.1%
1zpyA00 6.10.140.1960 Special › Helix non-globular › Helix Hairpins › 0.87 65.0 5.50e-01 78.0% 65.9%
4ceiA03 6.10.250.2380 Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.87 64.0 4.98e-01 76.3% 42.9%
2yevA02 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.87 62.0 5.69e-01 74.6% 64.9%
3pt1A02 1.20.930.60 Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › 0.86 61.0 4.76e-01 74.6% 36.7%
3fnbA01 1.20.1440.110 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › acylaminoacyl peptidase 0.86 66.0 5.18e-01 81.4% 49.1%
3qf7A02 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.84 63.0 6.15e-01 78.0% 74.6%
1vp7A00 1.10.287.1040 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Exonuclease VII, small subunit 0.83 64.0 6.06e-01 84.7% 70.6%
4h63K00 1.10.287.3490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.83 61.0 5.11e-01 78.0% 50.0%
4aifA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.83 64.0 4.75e-01 83.1% 41.0%
7odyC01 1.10.287.1080 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like 0.82 74.0 6.26e-01 98.3% 65.2%
2q1fA02 1.50.10.100 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › Chondroitin AC/alginate lyase 0.82 72.0 4.24e-01 94.9% 20.3%
3rkvA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.82 63.0 4.64e-01 83.1% 39.5%
4yonA01 1.20.900.10 Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain 0.81 67.0 4.49e-01 89.8% 46.8%
3kfwX03 1.20.58.1460 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.81 55.0 5.07e-01 74.6% 55.3%
2o8pA00 1.20.190.20 Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › 14-3-3 domain 0.81 63.0 4.15e-01 83.1% 37.4%
4dkcB00 1.20.1250.80 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › Interleukin-34 0.80 72.0 5.09e-01 96.6% 63.7%
1n1cA02 1.20.1280.20 Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain 0.80 63.0 5.61e-01 84.7% 73.2%
4gyvE00 1.20.900.10 Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain 0.80 66.0 4.40e-01 89.8% 45.6%
2rpaA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.79 61.0 5.59e-01 83.1% 75.3%
3hl1A02 6.10.140.1530 Special › Helix non-globular › Helix Hairpins › 0.79 51.0 4.92e-01 76.3% 60.0%
1exzB00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.78 71.0 5.24e-01 98.3% 62.9%
2kmfA01 1.20.58.810 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Photosystem II Pbs27 0.78 55.0 4.65e-01 76.3% 45.1%
3hiuD00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.78 69.0 4.96e-01 94.9% 63.8%
3fseB02 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.78 69.0 5.04e-01 94.9% 68.1%
4cpgA00 1.20.5.420 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C 0.75 53.0 5.06e-01 74.6% 63.8%
5b1oA00 1.10.287.130 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain 0.74 52.0 5.06e-01 74.6% 70.8%
3edvB01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.74 57.0 4.37e-01 84.7% 60.3%
3pe0A01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.73 60.0 4.97e-01 88.1% 82.2%
5nohA00 1.20.120.1350 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Pneumovirus matrix protein 2 (M2), zinc-binding domain 0.73 58.0 4.80e-01 89.8% 49.5%
1k90B03 1.20.140.60 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › 0.73 61.0 4.91e-01 93.2% 69.6%
3gs3A00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.73 57.0 3.77e-01 88.1% 23.3%
4abxA02 6.10.140.1090 Special › Helix non-globular › Helix Hairpins › 0.72 52.0 4.65e-01 78.0% 59.8%
3lnnB03 1.10.287.470 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.72 54.0 5.18e-01 79.7% 76.1%
3gnlB02 1.10.287.1890 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.72 56.0 5.46e-01 88.1% 98.5%
2l35A00 1.10.287.770 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like 0.72 50.0 4.95e-01 74.6% 73.0%
2yqdA00 1.20.920.10 Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like 0.71 57.0 4.51e-01 88.1% 81.7%
4kp3C00 1.20.58.1770 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.70 52.0 4.69e-01 79.7% 60.5%
4e6nA02 6.10.140.1010 Special › Helix non-globular › Helix Hairpins › 0.70 50.0 4.88e-01 78.0% 77.3%
3fppA03 6.10.140.1990 Special › Helix non-globular › Helix Hairpins › 0.67 48.0 4.24e-01 76.3% 71.6%
1zhcA00 6.10.280.50 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.67 48.0 4.50e-01 78.0% 61.8%
3rx6A00 1.20.58.1090 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phage polarity suppression protein monomer 0.66 48.0 3.40e-01 78.0% 25.7%
3nzpB03 1.20.58.930 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.65 54.0 4.97e-01 94.9% 92.4%
2gsvA00 6.10.140.40 Special › Helix non-globular › Helix Hairpins › 0.65 53.0 5.09e-01 89.8% 92.5%
4aurA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.60 42.0 2.79e-01 76.3% 16.6%
1yq1A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.58 43.0 3.63e-01 83.1% 65.2%
4jvyB00 3.30.1370.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 0.56 41.0 3.05e-01 83.1% 91.6%
1ciiA03 1.10.490.30 Mainly Alpha › Orthogonal Bundle › Globin-like › Colicin 0.51 40.0 3.14e-01 94.9% 46.5%
ECOD (82)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4202466 192.6.1.0 alpha bundles › Long alpha-hairpin › Epsilon subunit of F1F0-ATP synthase C-terminal domain › Epsilon subunit of F1F0-ATP synthase C-terminal domain 0.99 71.0 8.17e-01 74.6% 97.8%
4213046 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.97 71.0 6.87e-01 76.3% 69.2%
3983659 4970.1.1.0 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I 0.96 71.0 6.83e-01 76.3% 69.2%
3406025 221.1.1.0 a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like 0.96 77.0 6.45e-01 83.1% 54.4%
3809145 5076.2.1.10 alpha complex topology › Mitochondrial ADP/ATP carrier-like › Putative sulfate permease CysZ › Putative sulfate permease CysZ › PF29520 0.96 71.0 4.30e-01 76.3% 15.3%
3348106 5076.2.1.10 alpha complex topology › Mitochondrial ADP/ATP carrier-like › Putative sulfate permease CysZ › Putative sulfate permease CysZ › PF29520 0.96 71.0 4.37e-01 76.3% 16.7%
4972401 2484.1.1.124 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › OrfB_IS605 0.95 70.0 4.55e-01 76.3% 20.9%
4978165 2484.1.1.124 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › OrfB_IS605 0.95 70.0 4.62e-01 76.3% 22.5%
4959101 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.95 70.0 4.41e-01 76.3% 18.4%
4667859 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.95 71.0 5.49e-01 78.0% 40.9%
3676043 5076.2.1.10 alpha complex topology › Mitochondrial ADP/ATP carrier-like › Putative sulfate permease CysZ › Putative sulfate permease CysZ › PF29520 0.95 70.0 4.27e-01 76.3% 15.8%
3872955 109.4.1.2380 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_1, TPR_8, TPR_10, TPR_12, TPR_MalT 0.95 71.0 4.04e-01 78.0% 9.6%
3681637 603.1.1.5 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin-6_N 0.95 70.0 4.74e-01 76.3% 25.7%
3755476 3755.1.1.0 alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related 0.95 70.0 4.74e-01 76.3% 26.3%
3651038 192.29.1.221 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › PF29520 0.94 68.0 5.04e-01 74.6% 33.8%
3397137 386.1.1.0 few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers 0.93 70.0 6.36e-01 78.0% 62.7%
3418848 5076.2.1.10 alpha complex topology › Mitochondrial ADP/ATP carrier-like › Putative sulfate permease CysZ › Putative sulfate permease CysZ › PF29520 0.92 68.0 4.13e-01 76.3% 15.3%
3471215 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.92 68.0 6.13e-01 76.3% 60.0%
3594586 192.7.1.0 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm 0.92 69.0 5.70e-01 78.0% 49.5%
4977429 2484.1.1.124 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › OrfB_IS605 0.92 67.0 4.90e-01 76.3% 32.1%
4883924 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.91 68.0 6.03e-01 78.0% 58.7%
3669818 3922.1.1.284 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › PF29520 0.91 66.0 4.48e-01 76.3% 23.7%
4597007 192.6.1.0 alpha bundles › Long alpha-hairpin › Epsilon subunit of F1F0-ATP synthase C-terminal domain › Epsilon subunit of F1F0-ATP synthase C-terminal domain 0.91 65.0 7.38e-01 74.6% 97.8%
4544002 192.6.1.1 alpha bundles › Long alpha-hairpin › Epsilon subunit of F1F0-ATP synthase C-terminal domain › Epsilon subunit of F1F0-ATP synthase C-terminal domain › ATP-synt_DE 0.91 67.0 7.29e-01 78.0% 92.0%
5047797 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.91 66.0 6.02e-01 76.3% 60.0%
4977784 2484.1.1.302 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB 0.91 65.0 4.16e-01 74.6% 19.1%
3894565 4207.1.2.65 alpha duplicates or obligate multimers › Mediator hinge subcomplex-like › Mediator hinge subcomplex-like › MED7 hinge region › OLF 0.91 66.0 3.88e-01 76.3% 14.7%
4999337 2484.1.1.124 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › OrfB_IS605 0.90 64.0 4.59e-01 74.6% 28.4%
5020701 3755.3.1.637 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DUF7121 0.90 68.0 4.40e-01 79.7% 20.0%
3286637 2484.1.1.124 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › OrfB_IS605 0.90 64.0 4.49e-01 74.6% 26.7%
222003 133.1.1.1 alpha bundles › DH domain-like › DBL homology domain (DH-domain) › DBL homology domain (DH-domain) › RhoGEF 0.90 72.0 4.86e-01 84.7% 56.0%
3678444 5076.2.1.10 alpha complex topology › Mitochondrial ADP/ATP carrier-like › Putative sulfate permease CysZ › Putative sulfate permease CysZ › PF29520 0.90 65.0 4.03e-01 76.3% 15.9%
3742811 604.6.1.1 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › GAT 0.90 72.0 5.61e-01 84.7% 60.0%
3841109 192.29.1.293 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › SHCBP_N 0.90 67.0 5.46e-01 78.0% 47.0%
4998688 192.2.1.89 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › DUF7121 0.90 70.0 4.43e-01 86.4% 19.6%
2464385 192.27.1.0 alpha bundles › Long alpha-hairpin › Helical hairpin in putative tRNA methyltransferase › Helical hairpin in putative tRNA methyltransferase 0.89 79.0 7.76e-01 94.9% 100.0%
4541195 3755.3.1.470 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › T3SSipB 0.89 64.0 4.84e-01 76.3% 35.4%
3478793 133.1.1.0 alpha bundles › DH domain-like › DBL homology domain (DH-domain) › DBL homology domain (DH-domain) 0.88 71.0 4.72e-01 84.7% 43.0%
4170866 192.6.1.0 alpha bundles › Long alpha-hairpin › Epsilon subunit of F1F0-ATP synthase C-terminal domain › Epsilon subunit of F1F0-ATP synthase C-terminal domain 0.88 62.0 7.00e-01 72.9% 95.6%
3271963 133.1.1.1 alpha bundles › DH domain-like › DBL homology domain (DH-domain) › DBL homology domain (DH-domain) › RhoGEF 0.88 64.0 4.51e-01 76.3% 27.3%
4581983 5086.1.1.13 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › T3SSipB 0.88 64.0 4.71e-01 76.3% 32.9%
3619957 5055.1.1.0 extended segments › Small-conductance potassium channel › Small-conductance potassium channel › Small-conductance potassium channel 0.88 72.0 6.25e-01 86.4% 72.9%
3642421 603.1.1.5 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin-6_N 0.88 69.0 5.25e-01 83.1% 67.2%
3937759 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.88 69.0 6.46e-01 83.1% 84.3%
3622515 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.87 69.0 5.97e-01 83.1% 69.4%
3219691 604.12.1.1 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT 0.87 68.0 6.41e-01 83.1% 82.9%
3931593 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.87 68.0 6.09e-01 83.1% 72.5%
3796589 604.12.1.1 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT 0.87 68.0 5.60e-01 83.1% 58.0%
4674738 133.1.1.0 alpha bundles › DH domain-like › DBL homology domain (DH-domain) › DBL homology domain (DH-domain) 0.87 73.0 4.81e-01 89.8% 49.5%
3874130 133.1.1.5 alpha bundles › DH domain-like › DBL homology domain (DH-domain) › DBL homology domain (DH-domain) › DH_Alsin 0.87 73.0 4.85e-01 89.8% 51.9%
5017725 2484.1.1.302 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB 0.87 62.0 4.15e-01 74.6% 23.1%
4935546 4163.1.1.0 alpha bundles › GINS helical bundle-like › GINS helical bundle-like › PSF1 N-terminal domain-like 0.87 69.0 5.14e-01 84.7% 49.6%
3964578 5094.1.1.1 a+b duplicates or obligate multimers › OmpH-like › OmpH-like › OmpH-like › OmpH 0.86 64.0 4.71e-01 78.0% 34.3%
1679505 4009.1.1.1 alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › ARMT1-like_dom 0.86 61.0 4.63e-01 74.6% 33.6%
5050698 10.28.1.1 beta sandwiches › jelly-roll › Jelly-roll domain in Zinc finger protein ZPR1 › Jelly-roll domain in Zinc finger protein ZPR1 › jr-ZPR1 0.86 68.0 5.10e-01 83.1% 48.1%
3510145 133.1.1.1 alpha bundles › DH domain-like › DBL homology domain (DH-domain) › DBL homology domain (DH-domain) › RhoGEF 0.86 73.0 4.99e-01 89.8% 56.1%
4947400 3684.1.1.0 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.86 67.0 4.95e-01 83.1% 77.9%
5048239 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.86 62.0 4.89e-01 76.3% 39.1%
4590389 4163.1.1.1 alpha bundles › GINS helical bundle-like › GINS helical bundle-like › PSF1 N-terminal domain-like › Sld5 0.86 68.0 4.88e-01 84.7% 44.5%
3935355 109.4.1.1950 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF30196 0.85 75.0 4.25e-01 93.2% 20.4%
3329196 604.6.1.1 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › GAT 0.85 68.0 5.59e-01 84.7% 68.0%
3719591 4121.1.1.0 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like 0.85 72.0 4.74e-01 89.8% 67.4%
4999332 3930.1.1.3 alpha bundles › Helical bundle insertion in helicase domains › Helical bundle in Hef helicase › Helical bundle in Hef helicase › RNA_helicase_helical 0.85 80.0 5.79e-01 100.0% 49.0%
4524004 604.11.1.1 alpha bundles › Spectrin repeat-like › XseB-like › XseB-like › Exonuc_VII_S 0.84 71.0 6.47e-01 89.8% 72.0%
4966687 192.3.1.1 alpha bundles › Long alpha-hairpin › Fe,Mn superoxide dismutase (SOD), N-terminal domain › Fe,Mn superoxide dismutase (SOD), N-terminal domain › Sod_Fe_N 0.84 62.0 5.43e-01 78.0% 56.5%
3727274 3758.1.1.69 alpha bundles › Bacterial hemolysins-like › Bacterial hemolysins › Bacterial hemolysins › PF30554 0.83 66.0 4.30e-01 86.4% 21.3%
3890976 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.83 61.0 4.31e-01 78.0% 27.1%
3171326 604.6.1.1 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › GAT 0.83 65.0 5.50e-01 84.7% 70.5%
5070360 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.83 66.0 4.73e-01 94.9% 32.3%
3259409 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.83 76.0 5.62e-01 100.0% 65.7%
4446713 604.11.1.1 alpha bundles › Spectrin repeat-like › XseB-like › XseB-like › Exonuc_VII_S 0.82 69.0 6.32e-01 89.8% 70.7%
3615269 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.82 71.0 4.69e-01 91.5% 58.6%
3270399 133.1.1.1 alpha bundles › DH domain-like › DBL homology domain (DH-domain) › DBL homology domain (DH-domain) › RhoGEF 0.82 67.0 4.67e-01 89.8% 54.6%
5054723 633.12.1.1 alpha bundles › Bromodomain-like › Ta0600-like › Ta0600-like › UPF0147 0.81 64.0 5.63e-01 84.7% 97.6%
3167982 109.4.1.1677 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HAT_Syf1_M, HAT_Syf1_CNRKL1_N 0.80 67.0 4.01e-01 91.5% 47.3%
4276444 109.4.1.3238 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HopW1-1 0.79 72.0 4.56e-01 100.0% 37.5%
4932900 633.12.1.1 alpha bundles › Bromodomain-like › Ta0600-like › Ta0600-like › UPF0147 0.78 65.0 5.54e-01 89.8% 93.5%
3503054 192.4.1.13 alpha bundles › Long alpha-hairpin › Ribosomal protein L29 (L29p) › Ribosomal protein L29 (L29p) › Cactin_mid 0.78 73.0 5.00e-01 100.0% 63.2%
3722750 4121.1.1.0 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like 0.78 64.0 3.97e-01 89.8% 50.3%
3192393 2004.1.1.430 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran, ABC_tran_Xtn 0.77 71.0 3.97e-01 96.6% 23.3%
3577233 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.77 59.0 5.59e-01 83.1% 88.6%
3621567 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.75 57.0 4.21e-01 83.1% 40.0%