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SR-VP_0-2_scaffold_141_2510002_prodigal-single.1__X__X__00169
Bact-VirSR-VP_0-2_scaffold_141_2510002_prodigal-single.1__X__X__00169
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 3-21_35-89
Domain cluster:
representative
CATH (43)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4c0qB00 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.77 | 55.0 | 3.09e-01 | 74.3% | 15.1% |
| 1i4dA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.76 | 60.0 | 4.44e-01 | 85.1% | 85.6% |
| 2yfaB01 | 1.20.1440.210 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.76 | 62.0 | 5.21e-01 | 86.5% | 71.4% |
| 3kavA00 | 1.20.1270.360 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.76 | 68.0 | 6.13e-01 | 100.0% | 90.2% |
| 1lvfB00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.76 | 53.0 | 4.68e-01 | 73.0% | 91.3% |
| 3rguB00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.74 | 59.0 | 5.65e-01 | 87.8% | 93.1% |
| 6ygiB01 | 1.10.4090.10 | Mainly Alpha › Orthogonal Bundle › Hepatitis B viral capsid (hbcag) fold › Viral capsid, core domain supefamily, Hepatitis B virus | 0.74 | 61.0 | 4.86e-01 | 90.5% | 86.3% |
| 2qgmA03 | 1.20.1440.30 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Biosynthetic Protein domain | 0.73 | 52.0 | 4.48e-01 | 74.3% | 52.6% |
| 5figA00 | 1.20.1270.360 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.73 | 65.0 | 5.89e-01 | 100.0% | 85.0% |
| 2uxwA04 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.73 | 58.0 | 4.86e-01 | 87.8% | 71.5% |
| 2qffA00 | 1.20.1270.10 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.72 | 58.0 | 5.84e-01 | 87.8% | 89.2% |
| 1yo7A00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.72 | 63.0 | 5.42e-01 | 100.0% | 84.2% |
| 2d2sA01 | 1.20.58.1210 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Exo84p, N-terminal helical domain | 0.72 | 50.0 | 4.27e-01 | 73.0% | 50.9% |
| 4hkrA00 | 1.20.140.140 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Calcium release-activated calcium channel protein Orai | 0.71 | 60.0 | 4.67e-01 | 94.6% | 70.9% |
| 3axjB02 | 1.20.58.200 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 | 0.71 | 49.0 | 4.69e-01 | 71.6% | 84.7% |
| 2wyhB04 | 1.20.1270.50 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Glycoside hydrolase family 38, central domain | 0.71 | 57.0 | 5.13e-01 | 87.8% | 78.2% |
| 2oznB01 | 1.20.1270.90 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › AF1782-like | 0.70 | 56.0 | 5.52e-01 | 86.5% | 91.3% |
| 3n71A03 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.70 | 55.0 | 3.88e-01 | 82.4% | 85.9% |
| 1aepA00 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.70 | 62.0 | 4.91e-01 | 100.0% | 71.2% |
| 3f7cA00 | 1.20.1590.10 | Mainly Alpha › Up-down Bundle › YP_001051499.1 fold like › YP_001051499.1 domain like | 0.70 | 61.0 | 4.50e-01 | 100.0% | 71.9% |
| 2ip6A00 | 1.20.1440.140 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.70 | 63.0 | 5.97e-01 | 100.0% | 92.0% |
| 1wfdA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.69 | 50.0 | 4.63e-01 | 75.7% | 67.7% |
| 7k18A01 | 1.20.120.350 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C | 0.69 | 54.0 | 4.47e-01 | 86.5% | 58.2% |
| 2qupA00 | 1.20.120.490 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hypothetical protein TM1646-like domain | 0.68 | 47.0 | 4.05e-01 | 71.6% | 60.5% |
| 3s84A02 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.68 | 53.0 | 4.19e-01 | 85.1% | 80.3% |
| 1jr3C02 | 1.20.272.10 | Mainly Alpha › Up-down Bundle › Zinc Finger, Delta Prime; domain 3 › | 0.68 | 52.0 | 4.41e-01 | 82.4% | 71.3% |
| 2zxqA06 | 1.20.1270.70 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Designed single chain three-helix bundle | 0.67 | 51.0 | 5.36e-01 | 86.5% | 93.9% |
| 2h7oA01 | 1.20.120.1330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Rac1-binding domain, N-terminal GTPase binding subdomain | 0.66 | 46.0 | 3.87e-01 | 73.0% | 69.9% |
| 3thxB03 | 1.10.1420.10 | Mainly Alpha › Orthogonal Bundle › MutS, DNA mismatch repair protein; Chain A, domain 3 › | 0.65 | 51.0 | 3.87e-01 | 86.5% | 36.4% |
| 3u61D03 | 1.20.272.10 | Mainly Alpha › Up-down Bundle › Zinc Finger, Delta Prime; domain 3 › | 0.64 | 50.0 | 4.67e-01 | 85.1% | 68.1% |
| 3e3vA03 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.63 | 35.0 | 3.95e-01 | 100.0% | 71.4% |
| 3hl6A02 | 1.20.58.700 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.61 | 51.0 | 4.41e-01 | 91.9% | 66.1% |
| 2m6uA00 | 1.20.81.20 | Mainly Alpha › Up-down Bundle › Receptor-associated Protein › | 0.61 | 48.0 | 4.64e-01 | 85.1% | 90.2% |
| 1n5uA04 | 1.10.246.10 | Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › | 0.60 | 41.0 | 3.98e-01 | 74.3% | 62.8% |
| 1szhA02 | 1.10.150.370 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Caenorhabditis elegans Her-1, C-terminal domain | 0.59 | 45.0 | 4.43e-01 | 98.6% | 76.8% |
| 3rlfF01 | 1.20.58.370 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › MalF N-terminal region-like | 0.59 | 43.0 | 4.15e-01 | 78.4% | 72.1% |
| 2oebA00 | 1.10.520.30 | Mainly Alpha › Orthogonal Bundle › Peroxidase; domain 1 › AF1862-like domain | 0.58 | 45.0 | 3.59e-01 | 83.8% | 63.8% |
| 8ek4A01 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.57 | 39.0 | 3.29e-01 | 71.6% | 80.5% |
| 2cdqA02 | 1.20.120.1320 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartokinase, catalytic domain | 0.56 | 42.0 | 3.95e-01 | 85.1% | 91.8% |
| 2k3qA00 | 1.10.274.70 | Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Spidroin, N-terminal domain | 0.54 | 46.0 | 4.03e-01 | 98.6% | 74.6% |
| 7dluA01 | 1.10.287.1260 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.52 | 37.0 | 3.32e-01 | 74.3% | 71.4% |
| 7dswA01 | 1.20.1530.20 | Mainly Alpha › Up-down Bundle › Na+/H+ antiporter like fold › | 0.51 | 43.0 | 2.79e-01 | 100.0% | 57.8% |
| 3kjxD01 | 1.10.260.40 | Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains | 0.51 | 32.0 | 3.51e-01 | 81.1% | 78.7% |
ECOD (36)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3625011 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.84 | 78.0 | 5.99e-01 | 100.0% | 69.0% |
| 3468446 | 633.10.1.0 ↗ | alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like | 0.82 | 72.0 | 5.67e-01 | 94.6% | 99.3% |
| 3974363 | 5059.1.1.1 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA | 0.80 | 64.0 | 4.20e-01 | 85.1% | 66.7% |
| 5028461 | 632.7.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › HSP70 | 0.80 | 66.0 | 6.13e-01 | 87.8% | 74.4% |
| 4057506 | 632.7.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › HSP70 | 0.78 | 65.0 | 6.04e-01 | 89.2% | 75.6% |
| 4097522 | 601.25.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › TrmE connector domain › TrmE connector domain › MnmE_helical | 0.77 | 65.0 | 5.01e-01 | 90.5% | 49.0% |
| 3603132 | 633.12.1.0 ↗ | alpha bundles › Bromodomain-like › Ta0600-like › Ta0600-like | 0.77 | 61.0 | 5.95e-01 | 86.5% | 78.8% |
| 5029773 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.76 | 52.0 | 5.25e-01 | 70.3% | 79.7% |
| 3420431 | 632.7.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.75 | 60.0 | 5.73e-01 | 87.8% | 75.3% |
| 3704762 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.74 | 52.0 | 4.31e-01 | 73.0% | 63.2% |
| 3708236 | 633.6.1.6 ↗ | alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › ACAD9-ACADV_C | 0.74 | 57.0 | 5.14e-01 | 85.1% | 83.8% |
| 5010298 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.73 | 66.0 | 5.06e-01 | 100.0% | 72.0% |
| 3272056 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.73 | 59.0 | 4.70e-01 | 89.2% | 80.7% |
| 3286912 | 632.18.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › hypothetical protein PA2901 › hypothetical protein PA2901 | 0.73 | 58.0 | 5.36e-01 | 86.5% | 77.9% |
| 4988178 | 633.29.1.0 ↗ | alpha bundles › Bromodomain-like › Putative uncharacterized protein PAV1-137 › Putative uncharacterized protein PAV1-137 | 0.71 | 63.0 | 5.79e-01 | 100.0% | 94.7% |
| 3426824 | 3352.1.1.4 ↗ | alpha bundles › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › Alg6_Alg8 | 0.69 | 60.0 | 3.70e-01 | 100.0% | 54.0% |
| 3634546 | 632.15.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Staphylococcal complement inhibitor (SCIN) › Staphylococcal complement inhibitor (SCIN) | 0.69 | 54.0 | 5.47e-01 | 86.5% | 88.0% |
| 3859555 | 601.19.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein › Apolipoprotein | 0.69 | 53.0 | 4.04e-01 | 85.1% | 70.0% |
| 4015874 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.68 | 59.0 | 4.51e-01 | 98.6% | 78.3% |
| 4367522 | 601.14.1.12 ↗ | alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin › Rab3-GAP_cat_C | 0.67 | 53.0 | 4.17e-01 | 86.5% | 42.5% |
| 3709988 | 1189.1.1.0 ↗ | alpha bundles › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor | 0.67 | 52.0 | 4.12e-01 | 87.8% | 80.6% |
| 3831792 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.66 | 58.0 | 4.06e-01 | 100.0% | 53.3% |
| 3237264 | 3755.4.1.82 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Snf7 | 0.66 | 52.0 | 4.36e-01 | 86.5% | 82.3% |
| 3483099 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.66 | 46.0 | 4.17e-01 | 73.0% | 77.0% |
| 3261143 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.65 | 53.0 | 3.98e-01 | 87.8% | 70.7% |
| 3586713 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.63 | 45.0 | 3.48e-01 | 74.3% | 50.3% |
| 4620700 | 5050.1.1.81 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › TerC | 0.62 | 49.0 | 3.43e-01 | 86.5% | 77.2% |
| 5025162 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.62 | 47.0 | 3.57e-01 | 81.1% | 69.1% |
| 3535922 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.61 | 43.0 | 3.40e-01 | 73.0% | 81.3% |
| 3916668 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.60 | 47.0 | 4.16e-01 | 86.5% | 77.3% |
| 4990077 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.59 | 52.0 | 3.88e-01 | 100.0% | 84.6% |
| 4597483 | 5058.1.1.1 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1,MS_channel_1st | 0.59 | 41.0 | 3.50e-01 | 73.0% | 60.8% |
| 4317794 | 5058.1.1.1 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1,MS_channel_1st | 0.58 | 41.0 | 3.63e-01 | 73.0% | 69.5% |
| 3601679 | 310.2.1.0 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF | 0.56 | 39.0 | 3.14e-01 | 73.0% | 86.5% |
| 3507969 | 3755.3.1.420 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › PTHB1_hp | 0.55 | 47.0 | 3.66e-01 | 98.6% | 92.6% |
| 4175269 | 225.1.1.0 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0.55 | 43.0 | 2.72e-01 | 86.5% | 54.3% |