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SR-VP_0-2_scaffold_141_316084_prodigal-single.1__X__X__00440

Bact-Vir

SR-VP_0-2_scaffold_141_316084_prodigal-single.1__X__X__00440

Identity

Kingdom:
phage

Quality

89.4 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 155-257
PDB
CATH (44)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3b0xA03 3.30.460.10 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2 0.87 76.0 7.59e-01 100.0% 90.5%
2w9mB03 3.30.460.10 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2 0.83 62.0 6.91e-01 97.1% 98.8%
5hr9A01 3.30.460.10 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2 0.83 74.0 7.38e-01 96.1% 97.2%
3oguA03 3.30.460.10 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2 0.81 76.0 7.11e-01 100.0% 94.3%
4p4mA02 3.30.460.10 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2 0.81 72.0 6.91e-01 95.1% 100.0%
2bcqA03 3.30.460.10 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2 0.81 75.0 7.05e-01 100.0% 91.9%
6fgjA01 3.30.460.10 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2 0.80 74.0 6.42e-01 99.0% 95.3%
2ihmB03 3.30.460.10 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2 0.77 69.0 6.67e-01 97.1% 99.1%
4xq7A01 3.30.460.10 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2 0.76 70.0 5.99e-01 99.0% 84.0%
4fh3A02 3.30.460.10 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2 0.76 70.0 6.51e-01 100.0% 90.4%
4ebjA01 3.30.460.10 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2 0.76 59.0 5.49e-01 100.0% 66.4%
2nrkA00 3.30.460.10 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2 0.75 69.0 5.83e-01 100.0% 64.2%
1ib8A02 2.30.30.180 Mainly Beta › Roll › SH3 type barrels. › Ribosome maturation factor RimP, C-terminal domain 0.72 28.0 3.51e-01 87.4% 55.2%
6iw6A02 3.30.460.10 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2 0.72 65.0 6.42e-01 98.1% 97.2%
1r89A02 3.30.460.10 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2 0.72 65.0 6.08e-01 100.0% 88.3%
3hj4A02 3.30.460.10 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2 0.72 65.0 6.02e-01 100.0% 90.8%
7qprA02 3.30.460.10 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2 0.71 65.0 5.94e-01 100.0% 91.9%
4s3nA01 3.30.460.10 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2 0.71 64.0 5.68e-01 100.0% 86.4%
1vj7B02 3.30.460.10 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2 0.70 63.0 6.02e-01 97.1% 92.4%
3c18A01 3.30.460.10 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2 0.68 48.0 4.68e-01 93.2% 66.1%
3upsA00 3.30.460.10 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2 0.68 58.0 5.76e-01 96.1% 88.0%
2fclA00 3.30.460.40 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › 0.67 61.0 5.26e-01 99.0% 71.2%
3wfoA01 3.30.460.10 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2 0.66 57.0 4.94e-01 94.2% 66.2%
7lt2A01 3.30.460.90 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › 0.66 58.0 4.49e-01 100.0% 89.4%
4wqkA00 3.30.460.40 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › 0.66 58.0 4.88e-01 97.1% 60.0%
1ml8A02 3.30.300.20 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain 0.64 55.0 5.65e-01 97.1% 99.0%
1zswA02 3.10.180.10 Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 0.62 44.0 3.88e-01 72.8% 92.7%
1kw3B02 3.10.180.10 Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 0.62 46.0 4.03e-01 77.7% 87.7%
3p8aA02 2.60.40.4320 Mainly Beta › Sandwich › Immunoglobulin-like › 0.62 38.0 4.00e-01 99.0% 68.9%
2r5vA01 3.10.180.10 Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 0.61 45.0 3.98e-01 77.7% 88.0%
1sp8C01 3.10.180.10 Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 0.60 47.0 3.96e-01 83.5% 88.0%
1sqiA01 3.10.180.10 Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 0.60 47.0 3.99e-01 83.5% 87.4%
3e0rB01 3.10.180.10 Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 0.58 42.0 4.03e-01 75.7% 100.0%
3rmuA00 3.10.180.10 Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 0.58 41.0 3.74e-01 72.8% 100.0%
2kheA00 3.30.2310.20 Alpha Beta › 2-Layer Sandwich › YaeB-like fold › RelE-like 0.57 35.0 3.70e-01 96.1% 68.5%
4gafB03 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.55 38.0 3.78e-01 92.2% 67.3%
6h1bA02 3.30.300.30 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › ANL, C-terminal domain 0.54 42.0 4.22e-01 99.0% 83.3%
3ghjA00 3.10.180.10 Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 0.54 46.0 4.43e-01 95.1% 92.2%
1twuA00 3.10.180.10 Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 0.53 47.0 4.28e-01 98.1% 88.3%
6fgcA01 3.40.980.10 Alpha Beta › 3-Layer(aba) Sandwich › Molybdenum Cofactor Biosythetic Enzyme; Chain A › MoaB/Mog-like domain 0.53 46.0 3.93e-01 100.0% 75.1%
3vl9B00 2.60.120.180 Mainly Beta › Sandwich › Jelly Rolls › Glycoside hydrolase family 11/12, catalytic domain 0.52 43.0 3.40e-01 90.3% 67.0%
4qt4A00 3.40.50.1470 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Peptidyl-tRNA hydrolase 0.52 34.0 2.87e-01 100.0% 37.0%
3qpbF00 3.40.50.1580 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nucleoside phosphorylase domain 0.51 40.0 3.08e-01 86.4% 66.9%
6k5gA01 3.40.50.1580 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nucleoside phosphorylase domain 0.51 41.0 3.09e-01 88.3% 51.7%
ECOD (59)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4957215 316.1.1.23 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › DNA_pol_B_thumb 0.90 75.0 6.19e-01 100.0% 52.9%
4263916 316.1.1.23 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › DNA_pol_B_thumb 0.90 81.0 6.50e-01 100.0% 53.9%
4963116 316.1.1.23 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › DNA_pol_B_thumb 0.88 77.0 6.11e-01 100.0% 49.5%
1240966 316.1.1.23 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › DNA_pol_B_thumb 0.87 77.0 6.12e-01 100.0% 50.8%
1952984 316.1.1.23 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › DNA_pol_B_thumb 0.83 78.0 6.38e-01 100.0% 61.0%
1952982 316.1.1.4 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › NTP_transf_2,DNA_pol_B_thumb 0.83 78.0 6.35e-01 100.0% 60.7%
3733909 316.1.1.24 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › DNA_pol_B_thumb,DNA_pol_B_palm 0.79 73.0 5.40e-01 100.0% 56.9%
5077927 316.1.1.0 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase 0.78 71.0 6.20e-01 100.0% 82.6%
4039160 316.1.1.2 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › NTP_transf_2 0.77 71.0 6.27e-01 100.0% 84.8%
4150338 316.1.1.2 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › NTP_transf_2 0.77 71.0 6.13e-01 100.0% 80.0%
4994516 316.1.1.2 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › NTP_transf_2 0.77 70.0 6.06e-01 100.0% 83.2%
4996904 316.1.1.2 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › NTP_transf_2 0.77 70.0 6.55e-01 98.1% 88.8%
5028843 316.1.1.27 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › Polbeta 0.75 52.0 5.26e-01 92.2% 70.5%
6824 316.1.1.13 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › RelA_SpoT 0.75 70.0 6.16e-01 100.0% 85.5%
4928718 316.1.1.2 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › NTP_transf_2 0.75 68.0 6.09e-01 100.0% 82.8%
4998667 316.1.1.0 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase 0.74 69.0 6.20e-01 98.1% 93.3%
4953678 316.1.1.2 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › NTP_transf_2 0.73 66.0 6.26e-01 97.1% 90.0%
5054115 316.1.1.2 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › NTP_transf_2 0.73 56.0 5.61e-01 97.1% 79.0%
5054759 316.1.1.2 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › NTP_transf_2 0.73 67.0 6.02e-01 100.0% 82.1%
3929556 2004.1.1.19 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Ras 0.72 45.0 3.66e-01 100.0% 35.1%
4816291 316.1.1.6 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › Mab-21 0.72 64.0 4.87e-01 100.0% 90.4%
5058410 316.1.1.27 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › Polbeta 0.70 58.0 5.83e-01 99.0% 86.7%
5032234 316.1.1.27 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › Polbeta 0.69 58.0 5.70e-01 100.0% 84.5%
3721514 316.1.1.0 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase 0.69 63.0 4.85e-01 100.0% 98.7%
5079184 316.1.1.0 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase 0.69 64.0 5.09e-01 100.0% 55.9%
5069234 316.1.1.0 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase 0.69 59.0 4.99e-01 97.1% 56.1%
4990267 316.1.1.39 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › DUF2204 0.69 61.0 4.95e-01 96.1% 55.9%
5041752 316.1.1.2 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › NTP_transf_2 0.69 56.0 5.49e-01 100.0% 80.5%
4934391 316.1.1.2 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › NTP_transf_2 0.68 57.0 5.58e-01 100.0% 83.6%
5078572 316.1.1.21 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › Aminoglyc_resit 0.68 61.0 5.29e-01 95.1% 68.7%
5078939 316.1.1.21 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › Aminoglyc_resit 0.68 62.0 5.37e-01 99.0% 69.7%
4969835 316.1.1.2 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › NTP_transf_2 0.68 57.0 5.56e-01 99.0% 83.6%
4972768 316.1.1.0 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase 0.68 60.0 4.39e-01 99.0% 37.5%
5068883 316.1.1.27 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › Polbeta 0.68 57.0 5.34e-01 99.0% 75.2%
4156614 316.1.1.1 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › PolyA_pol 0.67 57.0 5.23e-01 97.1% 70.4%
5029780 316.1.1.2 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › NTP_transf_2 0.67 61.0 5.48e-01 100.0% 77.9%
4323659 211.1.1.54 a+b two layers › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › PF27226 0.67 52.0 5.43e-01 92.2% 89.5%
6828 316.1.1.21 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › Aminoglyc_resit 0.67 61.0 5.25e-01 99.0% 70.7%
4993629 316.1.1.27 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › Polbeta 0.67 51.0 4.82e-01 97.1% 67.2%
5041862 316.1.1.27 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › Polbeta 0.66 48.0 4.61e-01 100.0% 65.8%
5013444 316.1.1.36 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › MTPAP-like_central 0.66 53.0 5.07e-01 100.0% 74.2%
3726440 316.1.1.0 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase 0.66 59.0 4.84e-01 99.0% 54.6%
5035610 316.1.1.18 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › AbiEii 0.66 59.0 4.63e-01 100.0% 47.7%
5057945 316.1.1.0 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase 0.65 56.0 5.01e-01 93.2% 95.2%
3179417 316.1.1.0 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase 0.65 57.0 5.57e-01 97.1% 91.3%
5011354 316.1.1.39 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › DUF2204 0.65 56.0 4.67e-01 100.0% 54.1%
5080470 316.1.1.21 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › Aminoglyc_resit 0.64 57.0 4.42e-01 100.0% 47.7%
3285546 211.1.1.0 a+b two layers › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase 0.64 46.0 4.57e-01 75.7% 99.1%
3424253 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.64 49.0 4.12e-01 80.6% 60.6%
4495995 316.1.1.1 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › PolyA_pol 0.63 54.0 5.03e-01 98.1% 74.6%
4995864 2004.1.1.19 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Ras 0.63 44.0 3.64e-01 98.1% 42.3%
4958430 316.1.1.0 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase 0.63 56.0 4.30e-01 100.0% 47.9%
3848075 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.58 43.0 3.38e-01 98.1% 37.7%
4224302 316.1.1.54 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › RlaP 0.57 42.0 4.09e-01 77.7% 70.0%
4934718 2006.1.3.0 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain 0.57 52.0 3.99e-01 99.0% 59.5%
3929875 211.1.1.0 a+b two layers › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase 0.52 40.0 4.26e-01 85.4% 90.3%
4941640 211.1.1.0 a+b two layers › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase 0.52 40.0 3.52e-01 87.4% 54.8%
3786890 874.1.1.0 a+b duplicates or obligate multimers › Smc hinge domain › Smc hinge domain › Smc hinge domain 0.51 44.0 3.67e-01 99.0% 62.1%
5043017 2006.1.3.0 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain 0.50 45.0 4.31e-01 98.1% 100.0%
D2 high residues 267-324
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF14791.12 best DNA_pol_B_thumb 57.2 1.80e-15 100.0% 84.1%
CATH (39)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3au2A04 3.30.210.10 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 3 › DNA polymerase, thumb domain 0.95 80.0 7.70e-01 100.0% 80.0%
2bcqA04 3.30.210.10 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 3 › DNA polymerase, thumb domain 0.90 83.0 7.92e-01 100.0% 95.5%
2w9mA04 3.30.210.10 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 3 › DNA polymerase, thumb domain 0.89 64.0 6.63e-01 86.2% 80.0%
4p4mA03 3.30.210.10 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 3 › DNA polymerase, thumb domain 0.89 82.0 6.89e-01 100.0% 81.5%
1bpeA04 3.30.210.10 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 3 › DNA polymerase, thumb domain 0.87 78.0 7.76e-01 98.3% 96.6%
5hr9A02 3.30.210.10 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 3 › DNA polymerase, thumb domain 0.78 65.0 6.19e-01 100.0% 78.3%
1jiwI00 2.40.128.10 Mainly Beta › Beta Barrel › Lipocalin › 0.64 49.0 4.07e-01 84.5% 95.2%
2nnwA01 3.30.420.220 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › 0.60 41.0 3.26e-01 72.4% 95.9%
2hjjA00 3.30.160.130 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › ykff protein like domains 0.58 45.0 4.36e-01 87.9% 86.4%
7mhwA01 2.40.128.10 Mainly Beta › Beta Barrel › Lipocalin › 0.58 41.0 3.65e-01 75.9% 100.0%
7atrA01 3.10.105.10 Alpha Beta › Roll › Dipeptide-binding Protein; domain 3 › Dipeptide-binding Protein; Domain 3 0.57 49.0 3.21e-01 94.8% 62.7%
6hgcA01 3.40.532.10 Alpha Beta › 3-Layer(aba) Sandwich › Ubiquitin C-terminal Hydrolase UCH-l3 › Peptidase C12, ubiquitin carboxyl-terminal hydrolase 0.57 42.0 3.05e-01 82.8% 77.0%
2wdtC02 3.30.1490.420 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › Ubiquitin carboxyl-terminal hydrolase, domain 2 0.57 43.0 3.64e-01 82.8% 58.4%
2jj6A00 2.60.120.200 Mainly Beta › Sandwich › Jelly Rolls › 0.57 42.0 3.31e-01 82.8% 86.6%
6accA01 2.60.120.960 Mainly Beta › Sandwich › Jelly Rolls › Spike glycoprotein, N-terminal domain 0.57 40.0 2.65e-01 75.9% 93.7%
7x4qA01 3.30.460.10 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2 0.57 42.0 3.15e-01 100.0% 31.1%
3gd0A02 3.30.920.50 Alpha Beta › 2-Layer Sandwich › Metal Transport, Frataxin; Chain A › Beta-1,3-glucanase, C-terminal domain 0.57 43.0 3.56e-01 84.5% 85.7%
3pvlA04 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.56 44.0 3.79e-01 87.9% 89.9%
5h4eA02 3.30.920.50 Alpha Beta › 2-Layer Sandwich › Metal Transport, Frataxin; Chain A › Beta-1,3-glucanase, C-terminal domain 0.56 43.0 3.55e-01 89.7% 82.4%
2j8gA03 2.20.120.10 Mainly Beta › Single Sheet › Multimodular pneumococcal cell wall endolysin, domain 3 › Multimodular pneumococcal cell wall endolysin, domain 3 0.55 44.0 4.42e-01 87.9% 87.9%
6vp6A03 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.55 46.0 2.95e-01 98.3% 71.2%
2m3xC02 2.40.10.360 Mainly Beta › Beta Barrel › Thrombin, subunit H › 0.55 41.0 3.97e-01 84.5% 72.5%
3ui3A02 3.30.70.240 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.55 46.0 3.89e-01 98.3% 55.1%
3fysA02 3.30.1180.10 Alpha Beta › 2-Layer Sandwich › Hypothetical Protein Tm841; Chain: A;domain 3 › 0.54 41.0 3.27e-01 84.5% 57.4%
3lvuB00 3.10.105.10 Alpha Beta › Roll › Dipeptide-binding Protein; domain 3 › Dipeptide-binding Protein; Domain 3 0.54 45.0 2.99e-01 94.8% 62.3%
2jmbA00 2.40.128.290 Mainly Beta › Beta Barrel › Lipocalin › Uncharacterised protein family Atu4866 0.54 39.0 3.62e-01 81.0% 83.5%
3nytA02 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.53 43.0 3.42e-01 87.9% 91.3%
1nktA02 3.90.1440.10 Alpha Beta › Alpha-Beta Complex › Pre-protein croslinking domain of SecA › SecA, preprotein cross-linking domain 0.53 38.0 3.02e-01 79.3% 36.1%
3k9dA02 3.40.309.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 2 › Aldehyde Dehydrogenase; Chain A, domain 2 0.52 41.0 3.05e-01 98.3% 29.7%
2b02A01 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.52 36.0 3.02e-01 72.4% 57.7%
3uxuA00 1.10.443.10 Mainly Alpha › Orthogonal Bundle › hpI Integrase; Chain A › Intergrase catalytic core 0.52 44.0 3.27e-01 96.6% 62.9%
3hr8A02 3.30.250.10 Alpha Beta › 2-Layer Sandwich › Rec A Protein; domain 2 › RecA protein, C-terminal domain 0.52 35.0 3.27e-01 75.9% 54.7%
5j3tA00 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.51 40.0 3.32e-01 94.8% 96.8%
3kkjA01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.51 41.0 3.02e-01 87.9% 93.5%
4cy8A03 3.40.30.120 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › 0.51 37.0 2.85e-01 81.0% 45.6%
6s9vB01 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.51 36.0 2.24e-01 75.9% 23.8%
2yf0A01 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.51 37.0 3.36e-01 82.8% 98.9%
6xl1A01 3.40.50.10770 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Hypothetical protein VC1899 like domain (Restriction endonuclease-like) 0.50 40.0 3.01e-01 89.7% 81.9%
2frxA02 3.10.450.720 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.50 40.0 2.91e-01 87.9% 39.6%
ECOD (42)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4963116 316.1.1.23 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › DNA_pol_B_thumb 0.93 88.0 5.85e-01 100.0% 33.7%
3276647 316.1.1.24 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › DNA_pol_B_thumb,DNA_pol_B_palm 0.92 85.0 5.75e-01 100.0% 31.2%
3726426 316.1.1.24 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › DNA_pol_B_thumb,DNA_pol_B_palm 0.91 85.0 5.57e-01 100.0% 30.5%
4951202 316.1.1.23 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › DNA_pol_B_thumb 0.89 77.0 5.49e-01 100.0% 34.8%
3610425 316.1.1.23 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › DNA_pol_B_thumb 0.89 80.0 5.17e-01 100.0% 24.6%
151074 316.1.1.24 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › DNA_pol_B_thumb,DNA_pol_B_palm 0.88 81.0 5.44e-01 100.0% 29.6%
3453703 316.1.1.24 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › DNA_pol_B_thumb,DNA_pol_B_palm 0.88 80.0 5.39e-01 100.0% 32.2%
3716929 316.1.1.24 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › DNA_pol_B_thumb,DNA_pol_B_palm 0.87 80.0 5.07e-01 98.3% 31.8%
3594958 316.1.1.0 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase 0.83 71.0 4.66e-01 100.0% 23.4%
3936594 386.1.1.0 few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers 0.62 48.0 4.67e-01 86.2% 80.0%
3953675 330.7.1.0 a+b two layers › dsRBD-like › PI-Pfui intein middle domain › PI-Pfui intein middle domain 0.62 50.0 4.83e-01 87.9% 100.0%
3478678 220.1.1.0 beta barrels › PH domain-like › PH domain-like › PH domain-like 0.60 45.0 4.14e-01 81.0% 81.3%
3175445 633.23.1.9 alpha bundles › Bromodomain-like › Claudin › Claudin › SUR7 0.60 46.0 3.18e-01 87.9% 56.0%
3990856 304.112.1.0 a+b two layers › Alpha-beta plaits › Argonaute, N-terminal domain › Argonaute, N-terminal domain 0.59 48.0 3.68e-01 91.4% 80.7%
3470049 2004.1.1.17 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Myosin_head 0.58 40.0 2.25e-01 70.7% 94.3%
5830 330.7.1.1 a+b two layers › dsRBD-like › PI-Pfui intein middle domain › PI-Pfui intein middle domain › DUF905 0.58 45.0 4.36e-01 87.9% 86.4%
3913314 220.1.1.64 beta barrels › PH domain-like › PH domain-like › PH domain-like › FERM_C1_MyoVII 0.58 43.0 3.51e-01 82.8% 89.2%
3716968 2004.1.1.17 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Myosin_head 0.58 39.0 2.20e-01 70.7% 91.3%
3311716 5.3.1.0 beta duplicates or obligate multimers › beta-propeller-like › beta-Prism II › beta-Prism II 0.58 45.0 3.50e-01 86.2% 86.9%
3867392 304.112.1.0 a+b two layers › Alpha-beta plaits › Argonaute, N-terminal domain › Argonaute, N-terminal domain 0.57 48.0 3.06e-01 94.8% 62.9%
3379426 4205.1.1.0 a+b two layers › SMI1/KNR4-like › SMI1/KNR4-like › SMI1/KNR4-like 0.57 47.0 3.33e-01 96.6% 59.3%
3859170 304.112.1.0 a+b two layers › Alpha-beta plaits › Argonaute, N-terminal domain › Argonaute, N-terminal domain 0.57 48.0 3.73e-01 94.8% 77.4%
3439608 5.1.4.219 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › DPPIV_N 0.57 47.0 2.93e-01 100.0% 26.9%
3903484 220.1.1.64 beta barrels › PH domain-like › PH domain-like › PH domain-like › FERM_C1_MyoVII 0.57 44.0 3.67e-01 87.9% 79.1%
5036089 3407.1.1.2 mixed a+b and a/b › Nop N-terminal domain › Nop N-terminal domain › Nop N-terminal domain › Nop5_56-rel_N_Arc 0.57 40.0 3.17e-01 75.9% 96.8%
5017022 331.1.1.27 a+b two layers › TBP-like › TATA-box binding protein-like › TATA-box binding protein-like › CBS 0.56 47.0 3.08e-01 98.3% 27.7%
5013411 3407.1.1.2 mixed a+b and a/b › Nop N-terminal domain › Nop N-terminal domain › Nop N-terminal domain › Nop5_56-rel_N_Arc 0.55 39.0 3.19e-01 75.9% 98.3%
3777243 220.1.1.161 beta barrels › PH domain-like › PH domain-like › PH domain-like › PF26659 0.55 41.0 3.21e-01 82.8% 70.4%
3797675 5.1.3.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed 0.54 44.0 3.12e-01 96.6% 60.9%
4946976 3407.1.1.5 mixed a+b and a/b › Nop N-terminal domain › Nop N-terminal domain › Nop N-terminal domain › Nop 0.54 38.0 2.95e-01 75.9% 93.8%
4237290 570.1.1.1 alpha arrays › Pre-protein crosslinking domain of SecA › Pre-protein crosslinking domain of SecA › Pre-protein crosslinking domain of SecA › SecA_PP_bind 0.53 37.0 2.96e-01 75.9% 36.5%
4011407 223.1.1.0 a+b three layers › Profilin-like › sensor domains › sensor domains 0.53 41.0 3.23e-01 86.2% 57.7%
3748744 12.3.1.52 beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich › PF30771 0.52 41.0 2.85e-01 87.9% 25.1%
3955729 150.8.1.7 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › PPE › PPE › PF29644 0.52 46.0 3.33e-01 98.3% 35.8%
3641060 5.3.1.0 beta duplicates or obligate multimers › beta-propeller-like › beta-Prism II › beta-Prism II 0.52 40.0 3.15e-01 87.9% 85.9%
3702168 2004.1.1.17 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Myosin_head 0.52 43.0 2.45e-01 100.0% 29.7%
4022821 220.1.1.0 beta barrels › PH domain-like › PH domain-like › PH domain-like 0.52 42.0 3.21e-01 98.3% 74.8%
4526547 570.1.1.1 alpha arrays › Pre-protein crosslinking domain of SecA › Pre-protein crosslinking domain of SecA › Pre-protein crosslinking domain of SecA › SecA_PP_bind 0.51 40.0 3.19e-01 96.6% 41.7%
4023242 220.1.1.187 beta barrels › PH domain-like › PH domain-like › PH domain-like › VPS13_C 0.51 41.0 3.35e-01 94.8% 87.2%
2717225 7592.1.1.8 a/b three-layered sandwiches › CARF (CRISPR-associated Rossmann fold) domains › CARF (CRISPR-associated Rossmann fold) domains › CARF (CRISPR-associated Rossmann fold) domains › CARF_Card1 0.50 40.0 2.99e-01 89.7% 79.4%
5045224 2.1.1.0 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.50 37.0 3.38e-01 82.8% 82.4%
3696153 2003.1.2.15 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › FAD_binding_3 0.50 44.0 2.79e-01 100.0% 87.3%
D3 medium residues 1-98
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF14716.14 best HHH_8 35.4 1.60e-08 74.5% 97.3%
CATH (26)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3b0xA01 1.10.150.110 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › DNA polymerase beta, N-terminal domain-like 0.90 73.0 7.71e-01 83.7% 100.0%
2w9mB01 1.10.150.110 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › DNA polymerase beta, N-terminal domain-like 0.87 70.0 7.44e-01 83.7% 97.7%
4i2aA01 1.10.150.110 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › DNA polymerase beta, N-terminal domain-like 0.81 65.0 6.71e-01 91.8% 89.4%
1d2mA03 6.10.140.240 Special › Helix non-globular › Helix Hairpins › 0.70 45.0 5.29e-01 72.4% 95.5%
3tu3B03 1.20.1050.100 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.65 46.0 3.84e-01 74.5% 43.5%
5z7cA01 1.10.3210.10 Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432 0.63 52.0 4.40e-01 93.9% 93.8%
6k41R00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.62 50.0 3.78e-01 87.8% 95.9%
3i2fA02 1.10.3020.10 Mainly Alpha › Orthogonal Bundle › alpha-amino acid ester hydrolase ( Helical cap domain) › alpha-amino acid ester hydrolase ( Helical cap domain) 0.62 42.0 4.34e-01 74.5% 72.6%
2qffA00 1.20.1270.10 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.61 41.0 4.52e-01 83.7% 90.5%
7sf7A01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.61 50.0 3.65e-01 88.8% 91.5%
1tj7A01 1.10.275.10 Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › Fumarase/aspartase (N-terminal domain) 0.60 45.0 4.42e-01 79.6% 77.1%
1cnt200 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.60 42.0 3.78e-01 72.4% 63.1%
3iqcA00 1.20.120.340 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS 0.60 43.0 4.07e-01 82.7% 62.2%
2e8gA01 1.20.1440.150 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.59 49.0 4.55e-01 90.8% 86.3%
7f16R01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.56 49.0 3.60e-01 100.0% 71.1%
4gycA00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.55 47.0 3.72e-01 98.0% 77.7%
5xnyA01 1.10.275.10 Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › Fumarase/aspartase (N-terminal domain) 0.54 42.0 4.16e-01 84.7% 84.1%
4xt1A00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.54 49.0 3.50e-01 100.0% 62.5%
3h4cA01 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.54 41.0 4.15e-01 80.6% 100.0%
6mh4A03 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.53 38.0 4.12e-01 87.8% 91.1%
1b5lA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.53 38.0 3.30e-01 86.7% 48.0%
3vkgA15 1.10.8.1220 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.53 38.0 3.91e-01 74.5% 98.9%
4kc9A02 1.20.120.1750 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.53 45.0 3.56e-01 98.0% 100.0%
4fjvA02 1.20.1300.20 Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Peptidase C65 Otubain, subdomain 2 0.53 42.0 3.77e-01 88.8% 84.7%
2zt5A02 3.30.40.230 Alpha Beta › 2-Layer Sandwich › Herpes Virus-1 › 0.52 37.0 3.88e-01 81.6% 86.9%
6k9pB02 1.20.1300.20 Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Peptidase C65 Otubain, subdomain 2 0.52 42.0 3.67e-01 89.8% 86.2%
ECOD (36)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5072866 102.1.1.30 alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › HHH_8 0.94 76.0 8.15e-01 83.7% 100.0%
4033987 102.1.1.30 alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › HHH_8 0.92 73.0 8.09e-01 81.6% 100.0%
4945748 102.1.1.0 alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like 0.87 73.0 7.59e-01 87.8% 98.9%
5076953 102.1.1.30 alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › HHH_8 0.86 72.0 7.76e-01 95.9% 100.0%
3259835 102.1.1.30 alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › HHH_8 0.86 64.0 6.99e-01 78.6% 93.8%
3726429 102.1.1.30 alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › HHH_8 0.84 71.0 7.25e-01 91.8% 91.6%
4142133 133.1.1.7 alpha bundles › DH domain-like › DBL homology domain (DH-domain) › DBL homology domain (DH-domain) › PF28625 0.70 50.0 4.16e-01 73.5% 77.6%
1309041 633.18.1.1 alpha bundles › Bromodomain-like › ExoU toxin C-terminal domain › ExoU toxin C-terminal domain › ExoU_C 0.67 47.0 5.29e-01 74.5% 97.3%
3993365 5001.1.1.60 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srx 0.63 45.0 3.29e-01 74.5% 41.5%
3667299 592.2.1.11 alpha arrays › PWI domain-like › YugE-like › YugE-like › PF31137 0.63 48.0 4.64e-01 81.6% 83.6%
3697729 611.7.1.0 alpha bundles › N-cbl like › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Mixed lineage kinase domain-like (MLKL) N-terminal domain 0.62 51.0 4.10e-01 87.8% 47.6%
3499788 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.61 49.0 3.39e-01 87.8% 85.1%
4499455 633.5.1.1 alpha bundles › Bromodomain-like › LemA-like › LemA-like › LemA 0.60 43.0 3.70e-01 75.5% 60.0%
5053481 633.12.1.1 alpha bundles › Bromodomain-like › Ta0600-like › Ta0600-like › UPF0147 0.59 41.0 4.32e-01 72.4% 97.6%
3227671 5001.1.1.60 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srx 0.58 48.0 3.44e-01 89.8% 93.9%
4545635 1189.1.1.1 alpha bundles › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › Trypan_glycop 0.58 48.0 3.20e-01 88.8% 84.2%
3363306 611.7.1.16 alpha bundles › N-cbl like › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Mixed lineage kinase domain-like (MLKL) N-terminal domain › PUB2_N 0.58 44.0 3.90e-01 82.7% 85.3%
4001820 5001.1.1.63 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srab 0.58 40.0 3.43e-01 72.4% 82.4%
4201292 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.56 50.0 3.58e-01 100.0% 64.0%
3215515 632.1.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain 0.55 43.0 4.46e-01 82.7% 91.1%
3560739 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.55 48.0 3.44e-01 99.0% 63.3%
3935704 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.55 49.0 3.33e-01 100.0% 71.6%
3184071 633.21.1.0 alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 0.54 44.0 3.67e-01 88.8% 67.4%
3177312 633.23.1.22 alpha bundles › Bromodomain-like › Claudin › Claudin › MARVEL 0.54 45.0 3.99e-01 88.8% 83.6%
3610343 1189.1.1.1 alpha bundles › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › Trypan_glycop 0.54 42.0 2.89e-01 84.7% 67.4%
3215416 5001.1.1.63 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srab 0.53 48.0 3.31e-01 100.0% 67.4%
3486684 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.53 46.0 3.30e-01 99.0% 65.7%
3493622 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.53 46.0 3.28e-01 99.0% 64.7%
3478250 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.53 46.0 3.23e-01 99.0% 67.9%
3595135 193.1.1.0 alpha bundles › CH domain-like › Calponin-homology domain-like › Calponin-homology domain-like 0.53 44.0 4.37e-01 99.0% 85.7%
3689697 605.4.1.8 alpha duplicates or obligate multimers › ROP-like › ROP protein › ROP protein › MARVEL 0.52 41.0 4.31e-01 85.7% 98.9%
3783655 633.21.1.10 alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › MARVEL 0.52 42.0 3.77e-01 89.8% 73.8%
5072101 3651.1.1.1 alpha bundles › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › IF-2B 0.52 35.0 3.38e-01 96.9% 60.0%
3226467 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.51 42.0 3.85e-01 90.8% 80.7%
3478778 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.51 43.0 3.17e-01 99.0% 69.8%
3465921 611.2.1.2 alpha bundles › N-cbl like › N-terminal domain of cbl (N-cbl) › N-terminal domain of cbl (N-cbl) › Rx_N 0.50 42.0 3.84e-01 94.9% 92.6%
D4 medium residues 99-153
PDB
Domain cluster: representative
CATH (10)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2w9mA02 1.10.150.20 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 5' to 3' exonuclease, C-terminal subdomain 0.77 67.0 6.27e-01 100.0% 92.6%
2va8A04 1.10.150.20 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 5' to 3' exonuclease, C-terminal subdomain 0.74 63.0 6.32e-01 98.2% 100.0%
4i2aA02 1.10.150.20 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 5' to 3' exonuclease, C-terminal subdomain 0.68 58.0 5.76e-01 100.0% 93.2%
3osnA03 1.10.150.20 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 5' to 3' exonuclease, C-terminal subdomain 0.68 55.0 5.02e-01 94.5% 72.7%
2dkzA01 1.10.150.50 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Transcription Factor, Ets-1 0.62 51.0 5.03e-01 100.0% 100.0%
2is9A02 1.10.238.200 Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › Cullin, PONY binding domain 0.57 47.0 4.17e-01 100.0% 73.6%
2gscC00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.56 44.0 3.70e-01 94.5% 81.8%
4jgwA01 1.20.870.10 Mainly Alpha › Up-down Bundle › Son of sevenless (SoS) protein; Chain S, domain 1 › Son of sevenless (SoS) protein Chain: S domain 1 0.54 39.0 2.85e-01 78.2% 61.5%
2qyuA02 1.25.40.300 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Putative secreted effector protein 0.52 46.0 3.14e-01 100.0% 36.9%
4efcA03 1.10.40.30 Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase Protein R1; domain 1 › Fumarase/aspartase (C-terminal domain) 0.51 41.0 4.06e-01 98.2% 96.7%
ECOD (13)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4965166 102.5.1.1 alpha arrays › HhH/H2TH › SAM-like subdomain in Sec63-like proteins › SAM-like subdomain in Sec63-like proteins › HHH_5 0.74 63.0 6.15e-01 98.2% 96.7%
3908409 102.1.1.27 alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › HHH_5 0.74 64.0 5.82e-01 100.0% 89.3%
4944206 102.5.1.0 alpha arrays › HhH/H2TH › SAM-like subdomain in Sec63-like proteins › SAM-like subdomain in Sec63-like proteins 0.74 63.0 6.15e-01 100.0% 100.0%
2568242 102.1.1.21 alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › DNA_pol_lambd_f 0.73 61.0 5.99e-01 100.0% 86.9%
197595 102.5.1.1 alpha arrays › HhH/H2TH › SAM-like subdomain in Sec63-like proteins › SAM-like subdomain in Sec63-like proteins › HHH_5 0.73 63.0 6.24e-01 100.0% 98.3%
4364220 102.1.1.4 alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › 5_3_exonuc 0.72 61.0 4.83e-01 100.0% 55.8%
None 0.71 61.0 5.27e-01 100.0% 72.2%
3998341 102.5.1.9 alpha arrays › HhH/H2TH › SAM-like subdomain in Sec63-like proteins › SAM-like subdomain in Sec63-like proteins › DUF7898 0.71 60.0 5.63e-01 98.2% 88.6%
3286457 102.1.1.0 alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like 0.68 58.0 5.69e-01 100.0% 96.7%
3641047 102.1.1.4 alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › 5_3_exonuc 0.67 56.0 5.08e-01 100.0% 90.0%
3962074 102.1.1.0 alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like 0.67 57.0 5.26e-01 100.0% 84.0%
3359327 102.1.1.0 alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like 0.64 53.0 5.03e-01 100.0% 95.7%
3614897 376.1.1.1 few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box › zf-C3HC4 0.51 44.0 3.41e-01 100.0% 84.4%