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SR-VP_2-4_scaffold_141_2548329_prodigal-single.1__X__X__00233
Bact-VirSR-VP_2-4_scaffold_141_2548329_prodigal-single.1__X__X__00233
Identity
- Kingdom:
- phage
Quality
67.9
mean pLDDT
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 75-262
Domain cluster:
representative
CATH (9)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4ioeA00 | 1.10.287.850 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain | 0.61 | 24.0 | 3.44e-01 | 77.7% | 75.9% |
| 6fakA02 | 1.10.246.10 | Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › | 0.56 | 26.0 | 3.76e-01 | 87.2% | 100.0% |
| 3u9jA00 | 1.20.120.520 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › nmb1532 protein domain like | 0.53 | 34.0 | 3.70e-01 | 96.3% | 76.4% |
| 2qffA00 | 1.20.1270.10 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.52 | 23.0 | 3.39e-01 | 89.9% | 98.6% |
| 7kypB01 | 1.10.3470.10 | Mainly Alpha › Orthogonal Bundle › ABC transporter involved in vitamin B12 uptake, BtuC › ABC transporter involved in vitamin B12 uptake, BtuC | 0.52 | 39.0 | 3.45e-01 | 77.7% | 89.2% |
| 4lqxA00 | 1.20.910.10 | Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like | 0.52 | 43.0 | 3.65e-01 | 88.3% | 78.5% |
| 3ihuA02 | 1.20.120.530 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like | 0.51 | 35.0 | 4.04e-01 | 70.2% | 98.6% |
| 4hkrA00 | 1.20.140.140 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Calcium release-activated calcium channel protein Orai | 0.51 | 33.0 | 3.48e-01 | 86.2% | 72.1% |
| 5tgzA01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.50 | 37.0 | 3.22e-01 | 94.7% | 49.0% |
ECOD (4)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3279977 | 1075.5.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter | 0.68 | 39.0 | 3.79e-01 | 96.3% | 50.5% |
| 5083938 | 1075.5.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter | 0.65 | 37.0 | 3.78e-01 | 96.3% | 55.3% |
| 3921069 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.57 | 30.0 | 2.94e-01 | 75.5% | 44.9% |
| 5068817 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.55 | 32.0 | 3.03e-01 | 91.5% | 45.3% |
D2
medium
residues 18-74
Domain cluster:
representative
CATH (45)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5zg8A02 | 3.30.930.10 | Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 | 0.74 | 61.0 | 3.75e-01 | 89.5% | 86.6% |
| 3n2oA02 | 3.20.20.10 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Alanine racemase | 0.72 | 57.0 | 3.64e-01 | 87.7% | 98.6% |
| 3ehgA00 | 3.30.565.10 | Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain | 0.71 | 55.0 | 4.25e-01 | 84.2% | 73.6% |
| 1z7mC00 | 3.30.930.10 | Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 | 0.69 | 55.0 | 3.49e-01 | 89.5% | 95.7% |
| 2ox6D00 | 1.10.3100.10 | Mainly Alpha › Orthogonal Bundle › Putative cytoplasmic protein › Putative cytoplasmic protein | 0.65 | 44.0 | 3.28e-01 | 71.9% | 65.8% |
| 6vlxA01 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.65 | 45.0 | 2.96e-01 | 71.9% | 52.0% |
| 6torA02 | 3.40.640.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) | 0.65 | 55.0 | 3.62e-01 | 96.5% | 69.0% |
| 4ofzA02 | 3.40.50.1000 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like | 0.65 | 54.0 | 3.71e-01 | 96.5% | 88.4% |
| 7n0eB02 | 3.30.565.10 | Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain | 0.64 | 48.0 | 3.77e-01 | 80.7% | 69.7% |
| 1gcaA02 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.64 | 55.0 | 4.04e-01 | 100.0% | 95.0% |
| 3a0rA03 | 3.30.565.10 | Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain | 0.63 | 48.0 | 3.62e-01 | 82.5% | 95.9% |
| 4o2tA00 | 3.10.50.40 | Alpha Beta › Roll › Chitinase A; domain 3 › | 0.63 | 55.0 | 3.98e-01 | 100.0% | 92.9% |
| 3u4qB03 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.61 | 50.0 | 3.40e-01 | 93.0% | 67.4% |
| 6j7xA01 | 1.25.40.120 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Protein prenylyltransferase | 0.61 | 45.0 | 2.96e-01 | 82.5% | 19.6% |
| 1mqsA02 | 3.40.50.1910 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Sec1/Munc18 (SM) protein, domain 2 | 0.60 | 52.0 | 3.61e-01 | 100.0% | 77.9% |
| 1jp4A01 | 3.30.540.10 | Alpha Beta › 2-Layer Sandwich › Fructose-1,6-Bisphosphatase; Chain A, domain 1 › Fructose-1,6-Bisphosphatase, subunit A, domain 1 | 0.60 | 47.0 | 3.34e-01 | 86.0% | 73.4% |
| 3h78A02 | 3.40.47.10 | Alpha Beta › 3-Layer(aba) Sandwich › Peroxisomal Thiolase; Chain A, domain 1 › Thiolase/Chalcone synthase | 0.59 | 52.0 | 3.82e-01 | 100.0% | 66.5% |
| 4gczB03 | 3.30.565.10 | Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain | 0.59 | 52.0 | 3.75e-01 | 98.2% | 63.4% |
| 3g1wA02 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.59 | 51.0 | 3.82e-01 | 100.0% | 95.9% |
| 1eblA02 | 3.40.47.10 | Alpha Beta › 3-Layer(aba) Sandwich › Peroxisomal Thiolase; Chain A, domain 1 › Thiolase/Chalcone synthase | 0.59 | 49.0 | 3.81e-01 | 100.0% | 71.4% |
| 5q22A02 | 3.40.50.12650 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.58 | 47.0 | 3.68e-01 | 98.2% | 95.3% |
| 2orwB01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.58 | 50.0 | 3.93e-01 | 100.0% | 88.2% |
| 1souA00 | 3.40.50.10420 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NagB/RpiA/CoA transferase-like | 0.57 | 50.0 | 3.51e-01 | 100.0% | 83.5% |
| 1cseI00 | 3.30.10.10 | Alpha Beta › 2-Layer Sandwich › Trypsin Inhibitor V; Chain A › Trypsin Inhibitor V, subunit A | 0.57 | 45.0 | 4.43e-01 | 89.5% | 85.7% |
| 2efjA02 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.57 | 47.0 | 3.32e-01 | 100.0% | 97.7% |
| 4pl9A00 | 3.30.565.10 | Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain | 0.57 | 49.0 | 3.63e-01 | 98.2% | 63.3% |
| 2vk2A02 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.57 | 45.0 | 3.45e-01 | 98.2% | 92.1% |
| 5agaA01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.56 | 48.0 | 3.36e-01 | 100.0% | 79.2% |
| 1f0xB02 | 3.30.43.10 | Alpha Beta › 2-Layer Sandwich › Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 › Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 | 0.56 | 42.0 | 3.15e-01 | 80.7% | 36.1% |
| 3ilvA02 | 3.40.50.620 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs | 0.55 | 47.0 | 2.99e-01 | 100.0% | 93.6% |
| 3lkkB00 | 3.40.1160.10 | Alpha Beta › 3-Layer(aba) Sandwich › Carbamate kinase › Acetylglutamate kinase-like | 0.55 | 45.0 | 3.13e-01 | 100.0% | 39.5% |
| 1m0wA04 | 3.40.50.1760 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glutathione synthase, substrate-binding domain superfamily, eukaryotic | 0.55 | 47.0 | 3.72e-01 | 100.0% | 94.6% |
| 1id0A00 | 3.30.565.10 | Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain | 0.54 | 46.0 | 3.51e-01 | 100.0% | 93.2% |
| 5c3uA02 | 3.40.50.1100 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.54 | 40.0 | 3.43e-01 | 80.7% | 74.0% |
| 3pm9A01 | 3.30.43.10 | Alpha Beta › 2-Layer Sandwich › Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 › Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 | 0.54 | 40.0 | 3.45e-01 | 80.7% | 49.5% |
| 6rh8A02 | 3.30.565.10 | Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain | 0.54 | 47.0 | 3.46e-01 | 100.0% | 68.4% |
| 2cfbA02 | 3.40.640.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) | 0.54 | 44.0 | 3.06e-01 | 96.5% | 55.1% |
| 1xjcA00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.54 | 46.0 | 3.52e-01 | 100.0% | 92.4% |
| 5ybwA02 | 3.40.50.1100 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.54 | 39.0 | 3.35e-01 | 80.7% | 73.5% |
| 2p3nA01 | 3.30.540.10 | Alpha Beta › 2-Layer Sandwich › Fructose-1,6-Bisphosphatase; Chain A, domain 1 › Fructose-1,6-Bisphosphatase, subunit A, domain 1 | 0.54 | 43.0 | 3.47e-01 | 100.0% | 63.7% |
| 6dvsA02 | 3.40.640.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) | 0.53 | 42.0 | 2.96e-01 | 89.5% | 56.2% |
| 2x0dA02 | 3.40.50.2000 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; | 0.52 | 43.0 | 3.22e-01 | 100.0% | 74.6% |
| 3zm6A02 | 3.40.1190.10 | Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Mur-like, catalytic domain | 0.52 | 41.0 | 2.88e-01 | 94.7% | 31.4% |
| 5znqA00 | 3.40.50.2020 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.51 | 43.0 | 3.14e-01 | 100.0% | 89.6% |
| 1h65B00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.50 | 45.0 | 2.91e-01 | 100.0% | 29.7% |
ECOD (45)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4172936 | 2002.4.1.1 ↗ | a/b barrels › TIM beta/alpha-barrel › Nicotinate/Quinolinate PRTase C-terminal domain-like › Nicotinate/Quinolinate PRTase C-terminal domain-like › NAPRTase | 0.73 | 58.0 | 3.67e-01 | 87.7% | 72.6% |
| 3968308 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.72 | 56.0 | 4.25e-01 | 84.2% | 71.1% |
| 3974814 | 225.1.1.0 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0.71 | 56.0 | 4.20e-01 | 84.2% | 68.9% |
| 3796164 | 314.1.1.0 ↗ | a+b three layers › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases | 0.71 | 57.0 | 3.46e-01 | 89.5% | 94.3% |
| 4102143 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.68 | 52.0 | 3.85e-01 | 84.2% | 69.7% |
| 3386821 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.68 | 52.0 | 3.83e-01 | 82.5% | 98.0% |
| 4678236 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.68 | 51.0 | 3.62e-01 | 80.7% | 90.9% |
| 3694979 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.67 | 51.0 | 3.54e-01 | 82.5% | 93.2% |
| 4310791 | 109.4.1.18 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPTA | 0.67 | 50.0 | 2.99e-01 | 82.5% | 12.7% |
| 3643814 | 7572.1.1.0 ↗ | a/b three-layered sandwiches › Phosphofructokinase C-terminal domain › Phosphofructokinase C-terminal domain › Phosphofructokinase C-terminal domain | 0.67 | 52.0 | 3.51e-01 | 84.2% | 98.1% |
| 4997264 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.66 | 50.0 | 3.65e-01 | 82.5% | 79.8% |
| 4249356 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.65 | 49.0 | 3.57e-01 | 82.5% | 78.1% |
| 4291688 | 314.1.1.0 ↗ | a+b three layers › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases | 0.65 | 53.0 | 3.44e-01 | 100.0% | 32.9% |
| 3439867 | 2004.1.1.30 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C | 0.64 | 52.0 | 3.56e-01 | 87.7% | 75.8% |
| 3281466 | 2003.1.5.39 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_19 | 0.64 | 57.0 | 3.68e-01 | 100.0% | 74.7% |
| 3763416 | 109.4.1.18 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPTA | 0.63 | 47.0 | 2.91e-01 | 82.5% | 15.8% |
| 3969878 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.62 | 55.0 | 3.93e-01 | 98.2% | 65.6% |
| 5001124 | 2003.1.5.0 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases | 0.61 | 53.0 | 3.82e-01 | 100.0% | 92.0% |
| 4355768 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.60 | 52.0 | 3.82e-01 | 98.2% | 68.4% |
| 3633421 | 145.1.1.0 ↗ | alpha arrays › F-box domain › F-box domain › F-box domain | 0.60 | 43.0 | 2.48e-01 | 82.5% | 8.4% |
| 3972192 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.60 | 52.0 | 3.81e-01 | 98.2% | 67.1% |
| 4989134 | 2498.1.1.0 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" | 0.59 | 49.0 | 4.04e-01 | 98.2% | 55.7% |
| 4979214 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.58 | 45.0 | 3.10e-01 | 89.5% | 69.1% |
| 3924804 | 7570.1.1.4 ↗ | a/b three-layered sandwiches › MurD-like peptide ligases, peptide-binding domain › MurD-like peptide ligases, peptide-binding domain › MurD-like peptide ligases, peptide-binding domain › PF27239 | 0.57 | 49.0 | 3.69e-01 | 100.0% | 84.7% |
| 3387301 | 2003.1.7.5 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NagB/RpiA/CoA transferase-like › 5-FTHF_cyc-lig | 0.57 | 50.0 | 3.54e-01 | 100.0% | 87.8% |
| 1758615 | 301.9.1.1 ↗ | a+b three layers › Bacillus chorismate mutase-like › HypA Ni-binding domain › HypA Ni-binding domain › HypA | 0.57 | 44.0 | 3.87e-01 | 84.2% | 77.9% |
| 3966767 | 2005.3.1.1 ↗ | a/b three-layered sandwiches › HUP domain-like › Pyoverdine biosynthesis protein PvcA › Pyoverdine biosynthesis protein PvcA › DIT1_PvcA | 0.57 | 48.0 | 3.03e-01 | 96.5% | 61.6% |
| 4945353 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.56 | 47.0 | 3.46e-01 | 100.0% | 92.9% |
| 4506888 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.56 | 44.0 | 3.56e-01 | 91.2% | 54.2% |
| 4984856 | 2002.1.1.232 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Fer4_12 | 0.55 | 41.0 | 2.69e-01 | 78.9% | 23.4% |
| 4676609 | 4038.1.1.10 ↗ | alpha bundles › Alpha-helical domain in upper collar protein › Alpha-helical domain in upper collar protein › Alpha-helical domain in upper collar protein › Portal_Mu | 0.55 | 44.0 | 2.71e-01 | 86.0% | 28.9% |
| 3376596 | 2002.1.2.0 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › Hypothetical protein Cthe_0052 | 0.54 | 37.0 | 2.83e-01 | 71.9% | 40.0% |
| 4044189 | 2004.1.1.165 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DUF1846 | 0.54 | 43.0 | 2.77e-01 | 94.7% | 83.8% |
| 5023268 | 2003.1.6.0 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › Tubulin nucleotide-binding domain-like | 0.54 | 38.0 | 2.68e-01 | 96.5% | 20.5% |
| 317770 | 101.1.4.22 ↗ | alpha arrays › HTH › HTH › tetra-helical, lambda repressor-like › DUF4447 | 0.54 | 48.0 | 3.47e-01 | 100.0% | 62.6% |
| 4971273 | 2004.1.1.97 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MobB | 0.54 | 46.0 | 3.35e-01 | 100.0% | 90.0% |
| 3380495 | 7579.1.1.95 ↗ | a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Abhydrolase_1, Hydrolase_4 | 0.54 | 47.0 | 3.15e-01 | 100.0% | 97.9% |
| 5081473 | 7512.1.1.30 ↗ | a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_4 | 0.53 | 43.0 | 3.10e-01 | 91.2% | 91.4% |
| 4571275 | 2003.1.7.5 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NagB/RpiA/CoA transferase-like › 5-FTHF_cyc-lig | 0.53 | 45.0 | 3.22e-01 | 98.2% | 91.1% |
| 3587071 | 2007.1.2.10 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › Peripla_BP_3 | 0.53 | 45.0 | 3.39e-01 | 96.5% | 97.9% |
| 3332187 | 2003.1.5.13 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Spermine_synth | 0.52 | 41.0 | 2.76e-01 | 98.2% | 60.7% |
| 3782443 | 377.1.1.0 ↗ | few secondary structure elements › Glucocorticoid receptor-like › LIM domain-like › LIM domain-like | 0.52 | 44.0 | 3.27e-01 | 100.0% | 40.6% |
| 5048211 | 7584.1.1.0 ↗ | a/b three-layered sandwiches › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › Rossmann-like domain in Acetyl-CoA synthetase-like proteins | 0.51 | 42.0 | 2.56e-01 | 93.0% | 37.6% |
| 4927378 | 243.1.1.0 ↗ | a+b two layers › Cystatin-like › NTF2-like › NTF2-like | 0.51 | 41.0 | 3.37e-01 | 96.5% | 95.1% |
| 4516105 | 2004.1.1.165 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DUF1846 | 0.51 | 45.0 | 2.81e-01 | 100.0% | 82.6% |
D3
medium
residues 448-485_558-646
Domain cluster:
representative
CATH (18)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4f1jA00 | 3.40.50.410 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › von Willebrand factor, type A domain | 0.70 | 65.0 | 5.51e-01 | 99.2% | 98.0% |
| 6aikB00 | 3.40.50.10300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › CoaB-like | 0.66 | 59.0 | 4.47e-01 | 100.0% | 90.3% |
| 1d5rA01 | 3.90.190.10 | Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily | 0.59 | 40.0 | 3.65e-01 | 98.4% | 51.7% |
| 1gg1A00 | 3.20.20.70 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I | 0.54 | 49.0 | 3.61e-01 | 100.0% | 87.0% |
| 1oe4A00 | 3.40.470.10 | Alpha Beta › 3-Layer(aba) Sandwich › Uracil-DNA Glycosylase, subunit E › Uracil-DNA glycosylase-like domain | 0.54 | 48.0 | 3.89e-01 | 97.6% | 79.2% |
| 4q6bA02 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.54 | 43.0 | 4.24e-01 | 89.0% | 80.6% |
| 3lucA01 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.54 | 46.0 | 4.65e-01 | 96.9% | 100.0% |
| 4iqfB01 | 3.40.50.170 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Formyl transferase, N-terminal domain | 0.52 | 46.0 | 3.91e-01 | 96.1% | 90.9% |
| 3uw2A01 | 3.40.120.10 | Alpha Beta › 3-Layer(aba) Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 3 › Alpha-D-Glucose-1,6-Bisphosphate, subunit A, domain 3 | 0.52 | 36.0 | 3.45e-01 | 90.6% | 58.7% |
| 3fj1A01 | 3.40.50.10490 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 | 0.52 | 45.0 | 3.92e-01 | 95.3% | 68.4% |
| 3hbaA01 | 3.40.50.10490 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 | 0.52 | 45.0 | 3.94e-01 | 95.3% | 69.6% |
| 2x4lA02 | 3.40.50.1980 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nitrogenase molybdenum iron protein domain | 0.51 | 43.0 | 4.14e-01 | 92.9% | 84.6% |
| 5e7qA01 | 3.40.50.12780 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › ANL, N-terminal domain | 0.51 | 38.0 | 2.74e-01 | 91.3% | 25.1% |
| 2vk2A02 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.51 | 40.0 | 3.74e-01 | 86.6% | 77.6% |
| 2oayA01 | 3.30.497.10 | Alpha Beta › 2-Layer Sandwich › Antithrombin; Chain I, domain 2 › Antithrombin, subunit I, domain 2 | 0.51 | 40.0 | 3.51e-01 | 93.7% | 56.4% |
| 4ljsA02 | 3.40.50.1980 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nitrogenase molybdenum iron protein domain | 0.50 | 44.0 | 4.24e-01 | 96.1% | 86.9% |
| 1rifA02 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.50 | 37.0 | 3.24e-01 | 89.0% | 51.0% |
| 3b85A00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.50 | 36.0 | 3.17e-01 | 85.8% | 50.3% |
ECOD (32)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4939161 | 2004.1.1.101 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MeaB | 0.65 | 48.0 | 4.22e-01 | 96.9% | 53.3% |
| 4220780 | 2004.1.1.73 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MMR_HSR1 | 0.61 | 55.0 | 4.95e-01 | 99.2% | 98.3% |
| 3917662 | 2004.1.1.118 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AIG1 | 0.61 | 54.0 | 3.76e-01 | 99.2% | 38.9% |
| 3889205 | 2004.1.1.118 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AIG1 | 0.59 | 52.0 | 4.53e-01 | 98.4% | 90.4% |
| 3270756 | 2005.1.1.3 ↗ | a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › Usp | 0.58 | 45.0 | 4.27e-01 | 82.7% | 95.5% |
| 3985686 | 323.1.1.3 ↗ | a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding | 0.57 | 41.0 | 4.06e-01 | 90.6% | 68.6% |
| 4242967 | 323.1.1.3 ↗ | a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding | 0.57 | 37.0 | 3.58e-01 | 89.0% | 56.0% |
| 4683025 | 323.1.1.3 ↗ | a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding | 0.55 | 36.0 | 3.52e-01 | 87.4% | 58.6% |
| 3220345 | 323.1.1.3 ↗ | a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding | 0.55 | 38.0 | 3.68e-01 | 91.3% | 60.7% |
| 4247447 | 323.1.1.3 ↗ | a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding | 0.55 | 37.0 | 3.47e-01 | 90.6% | 53.3% |
| 2896511 | 2007.1.2.11 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › Peripla_BP_4 | 0.55 | 38.0 | 3.85e-01 | 80.3% | 70.2% |
| 3944366 | 323.1.1.3 ↗ | a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding | 0.55 | 36.0 | 3.60e-01 | 90.6% | 63.0% |
| 3385704 | 7579.1.1.92 ↗ | a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Abhydrolase_1, Abhydrolase_6 | 0.55 | 47.0 | 3.89e-01 | 96.1% | 90.4% |
| 10626 | 7569.1.1.1 ↗ | a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG | 0.54 | 48.0 | 3.89e-01 | 97.6% | 79.2% |
| 3084245 | 323.1.1.3 ↗ | a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding | 0.54 | 37.0 | 3.50e-01 | 93.7% | 56.1% |
| 3957590 | 323.1.1.3 ↗ | a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding | 0.54 | 38.0 | 3.61e-01 | 91.3% | 61.3% |
| 4875207 | 323.1.1.3 ↗ | a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding | 0.53 | 36.0 | 3.47e-01 | 91.3% | 58.7% |
| 4491503 | 323.1.1.3 ↗ | a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding | 0.53 | 30.0 | 3.24e-01 | 81.1% | 64.5% |
| 4015552 | 323.1.1.0 ↗ | a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases | 0.53 | 36.0 | 3.38e-01 | 87.4% | 56.1% |
| 3959033 | 323.1.1.0 ↗ | a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases | 0.52 | 34.0 | 3.19e-01 | 87.4% | 51.2% |
| 5005881 | 7584.1.1.1 ↗ | a/b three-layered sandwiches › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › AMP-binding | 0.52 | 37.0 | 3.55e-01 | 88.2% | 62.7% |
| 3002587 | 323.1.1.3 ↗ | a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding | 0.52 | 33.0 | 3.37e-01 | 87.4% | 65.3% |
| 4142091 | 323.1.1.3 ↗ | a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding | 0.52 | 37.0 | 3.45e-01 | 94.5% | 58.1% |
| 4401511 | 323.1.1.3 ↗ | a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding | 0.51 | 37.0 | 3.40e-01 | 91.3% | 56.5% |
| 4934467 | 7584.1.1.1 ↗ | a/b three-layered sandwiches › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › AMP-binding | 0.51 | 41.0 | 3.51e-01 | 88.2% | 54.0% |
| 4969874 | 7584.1.1.0 ↗ | a/b three-layered sandwiches › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › Rossmann-like domain in Acetyl-CoA synthetase-like proteins | 0.51 | 37.0 | 3.41e-01 | 89.0% | 57.1% |
| 5050282 | 7584.1.1.1 ↗ | a/b three-layered sandwiches › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › AMP-binding | 0.51 | 43.0 | 3.62e-01 | 90.6% | 63.8% |
| 430514 | 2003.1.5.80 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_24 | 0.51 | 40.0 | 3.28e-01 | 85.8% | 96.4% |
| 5052358 | 7584.1.1.1 ↗ | a/b three-layered sandwiches › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › AMP-binding | 0.50 | 42.0 | 3.53e-01 | 88.2% | 62.0% |
| 4053515 | 323.1.1.3 ↗ | a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding | 0.50 | 36.0 | 3.47e-01 | 96.1% | 63.3% |
| 5010064 | 7584.1.1.1 ↗ | a/b three-layered sandwiches › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › AMP-binding | 0.50 | 41.0 | 3.73e-01 | 85.8% | 66.1% |
| 4572461 | 323.1.1.3 ↗ | a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding | 0.50 | 37.0 | 3.26e-01 | 89.0% | 50.8% |
D4
medium
residues 486-557
Domain cluster:
representative
CATH (5)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4nxiA00 | 3.40.30.10 | Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin | 0.53 | 40.0 | 2.98e-01 | 81.9% | 69.4% |
| 1rypD00 | 3.60.20.10 | Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Aminohydrolase, N-terminal nucleophile (Ntn) domain | 0.52 | 43.0 | 3.01e-01 | 93.1% | 78.4% |
| 2yt7A01 | 2.30.42.10 | Mainly Beta › Roll › Pdz3 Domain › PDZ domain | 0.51 | 38.0 | 3.58e-01 | 79.2% | 78.2% |
| 1ihjA00 | 2.30.42.10 | Mainly Beta › Roll › Pdz3 Domain › PDZ domain | 0.51 | 37.0 | 3.44e-01 | 77.8% | 76.6% |
| 2kwaA00 | 3.30.1360.40 | Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › | 0.51 | 40.0 | 3.66e-01 | 88.9% | 99.0% |
ECOD (6)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3678667 | 304.31.1.1 ↗ | a+b two layers › Alpha-beta plaits › HMG-CoA reductase › NAD-binding domain of HMG-CoA reductase › HMG-CoA_red | 0.63 | 41.0 | 3.93e-01 | 91.7% | 56.5% |
| 3275766 | 2007.2.3.3 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › (Phosphotyrosine protein) phosphatases II › Syja_N | 0.60 | 43.0 | 2.83e-01 | 76.4% | 94.9% |
| 3855217 | 2002.1.1.106 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › GDPD | 0.55 | 44.0 | 2.91e-01 | 93.1% | 43.4% |
| 3682917 | 2484.1.1.2 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Actin | 0.54 | 35.0 | 2.58e-01 | 91.7% | 23.5% |
| 3424242 | 226.1.1.2 ↗ | a+b two layers › POZ domain › POZ domain › POZ domain › Skp1 | 0.53 | 39.0 | 3.17e-01 | 79.2% | 58.6% |
| 3227441 | 375.10.1.0 ↗ | few secondary structure elements › Rubredoxin-like › Zinc finger domain of DNA polymerase-alpha › Zinc finger domain of DNA polymerase-alpha | 0.52 | 36.0 | 3.89e-01 | 75.0% | 88.3% |