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SR-VP_4-6_scaffold_141_4086954_prodigal-single.1__X__X__00017

Bact-Vir

SR-VP_4-6_scaffold_141_4086954_prodigal-single.1__X__X__00017

Identity

Kingdom:
phage

Quality

59.3 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 728-793
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF18905.6 best DUF5661 38.1 2.10e-09 68.2% 63.1%
CATH (5)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4fzlA01 1.10.150.790 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 0.62 45.0 4.13e-01 77.3% 97.7%
2qgaB01 1.10.275.10 Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › Fumarase/aspartase (N-terminal domain) 0.59 48.0 3.96e-01 86.4% 62.3%
4yzgA00 3.60.40.10 Alpha Beta › 4-Layer Sandwich › Phosphatase 2c; domain 1 › PPM-type phosphatase domain 0.59 46.0 3.01e-01 86.4% 94.2%
6wb4B01 3.40.1190.20 Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase 0.57 47.0 3.06e-01 92.4% 26.6%
3k8kA02 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.53 36.0 2.29e-01 71.2% 83.1%
D2 medium residues 35-144
PDB
Domain cluster: representative
CATH (42)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3kztA00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.70 42.0 3.96e-01 79.1% 50.0%
1gydB00 2.115.10.20 Mainly Beta › 5 Propeller › Tachylectin-2; Chain A › Glycosyl hydrolase domain; family 43 0.68 45.0 3.17e-01 70.0% 23.2%
4hz9B00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.68 41.0 4.00e-01 79.1% 55.3%
2jq5A00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.67 40.0 3.79e-01 70.0% 50.0%
3doaA01 2.30.310.10 Mainly Beta › Roll › ibrinogen binding protein from staphylococcus aureus fold › ibrinogen binding protein from staphylococcus aureus domain 0.63 40.0 3.57e-01 83.6% 45.1%
2a15A00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.61 42.0 3.99e-01 70.9% 69.9%
3dukA00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.61 43.0 4.11e-01 72.7% 63.2%
3gp6A00 2.40.160.20 Mainly Beta › Beta Barrel › Porin › 0.61 49.0 4.38e-01 87.3% 78.7%
3lygA00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.60 43.0 4.17e-01 76.4% 66.7%
2vf9A00 3.30.380.10 Alpha Beta › 2-Layer Sandwich › MS2 Viral Coat Protein › MS2 Viral Coat Protein 0.60 42.0 4.02e-01 71.8% 77.1%
5evhA00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.59 40.0 3.93e-01 70.0% 64.5%
4bboA00 2.40.128.30 Mainly Beta › Beta Barrel › Lipocalin › Avidin-like 0.59 51.0 5.06e-01 92.7% 92.0%
1av4A03 2.70.98.20 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › Copper amine oxidase, catalytic domain 0.58 43.0 2.94e-01 79.1% 89.9%
2gxfA00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.57 42.0 4.08e-01 78.2% 69.5%
2w5nA00 2.120.10.10 Mainly Beta › 6 Propeller › Neuraminidase › 0.57 42.0 2.89e-01 75.5% 32.1%
5aigA00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.57 36.0 3.55e-01 76.4% 56.5%
3ebtA00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.57 42.0 3.94e-01 76.4% 67.9%
3al9A01 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.56 43.0 2.87e-01 82.7% 38.3%
2hzrA00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.55 44.0 3.83e-01 86.4% 57.1%
1omoA01 3.30.1780.10 Alpha Beta › 2-Layer Sandwich › ornithine cyclodeaminase, domain 1 › ornithine cyclodeaminase, domain 1 0.55 49.0 4.44e-01 98.2% 81.2%
1mmuA00 2.70.98.10 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › 0.55 45.0 3.18e-01 87.3% 70.8%
3lydA01 3.40.1000.10 Alpha Beta › 3-Layer(aba) Sandwich › Protein Transport Mog1p; Chain A › Mog1/PsbP, alpha/beta/alpha sandwich 0.55 42.0 3.90e-01 82.7% 73.9%
1jmxA02 2.40.128.120 Mainly Beta › Beta Barrel › Lipocalin › Quinohemoprotein amine dehydrogenase alpha subunit, domain 2 0.54 42.0 4.28e-01 89.1% 83.5%
1uypA01 2.115.10.20 Mainly Beta › 5 Propeller › Tachylectin-2; Chain A › Glycosyl hydrolase domain; family 43 0.54 39.0 2.88e-01 74.5% 34.3%
1tlyA00 2.40.230.20 Mainly Beta › Beta Barrel › Outer membrane phospholipase (ompla); Chain C › Nucleoside-specific channel-forming protein, Tsx-like 0.54 44.0 3.44e-01 90.0% 90.4%
3blcA00 2.70.98.90 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › 0.54 44.0 3.26e-01 87.3% 66.8%
3ecfA00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.54 41.0 3.94e-01 83.6% 69.5%
1bh3A00 2.40.160.10 Mainly Beta › Beta Barrel › Porin › Porin 0.54 43.0 3.20e-01 86.4% 62.3%
3hdjA01 3.30.1780.10 Alpha Beta › 2-Layer Sandwich › ornithine cyclodeaminase, domain 1 › ornithine cyclodeaminase, domain 1 0.53 47.0 4.31e-01 96.4% 82.1%
1l7aA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.53 43.0 3.10e-01 87.3% 89.6%
1qhlA00 3.40.1140.10 Alpha Beta › 3-Layer(aba) Sandwich › N-terminal domain of mukB › 0.53 41.0 3.37e-01 82.7% 87.2%
3wasA00 2.115.10.20 Mainly Beta › 5 Propeller › Tachylectin-2; Chain A › Glycosyl hydrolase domain; family 43 0.52 40.0 2.76e-01 81.8% 32.1%
4xrtA01 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.52 41.0 3.84e-01 85.5% 74.6%
3bgaA05 2.70.98.10 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › 0.52 42.0 3.15e-01 86.4% 87.0%
2g30A02 3.30.310.10 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › TATA-Binding Protein 0.51 42.0 4.16e-01 88.2% 100.0%
1a2vA03 2.70.98.20 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › Copper amine oxidase, catalytic domain 0.51 40.0 2.72e-01 85.5% 77.9%
1h91A00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.51 40.0 3.40e-01 89.1% 51.1%
1pu4A03 2.70.98.20 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › Copper amine oxidase, catalytic domain 0.51 39.0 2.75e-01 85.5% 83.8%
1f49A05 2.70.98.10 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › 0.51 40.0 2.98e-01 85.5% 71.0%
3otlA00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.50 45.0 4.05e-01 99.1% 94.1%
1pzdA02 3.30.310.10 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › TATA-Binding Protein 0.50 40.0 3.96e-01 83.6% 100.0%
1jkmA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.50 37.0 2.69e-01 80.0% 72.1%
ECOD (47)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3698492 216.1.1.0 ↗ a+b two layers › UBC-like › UBC-like › UBC-like 0.65 52.0 4.96e-01 83.6% 74.4%
3785652 243.1.1.2 ↗ a+b two layers › Cystatin-like › NTF2-like › NTF2-like › NTF2 0.65 48.0 4.18e-01 76.4% 58.1%
3352266 9.2.1.3 ↗ beta barrels › Lipocalins/Streptavidin › Avidin/Streptavidin › Avidin/Streptavidin › FBO_C 0.64 54.0 4.44e-01 89.1% 72.0%
4114942 9.1.1.0 ↗ beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins 0.62 52.0 4.44e-01 89.1% 56.0%
5057645 9.2.1.0 ↗ beta barrels › Lipocalins/Streptavidin › Avidin/Streptavidin › Avidin/Streptavidin 0.62 46.0 4.59e-01 77.3% 77.4%
3470047 243.1.1.2 ↗ a+b two layers › Cystatin-like › NTF2-like › NTF2-like › NTF2 0.61 43.0 4.87e-01 73.6% 96.5%
138908 243.1.1.18 ↗ a+b two layers › Cystatin-like › NTF2-like › NTF2-like › SnoaL_2 0.60 43.0 4.17e-01 76.4% 66.7%
4298119 12.3.1.6 ↗ beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich › Bgal_small_N 0.60 49.0 3.52e-01 85.5% 78.3%
4026686 883.1.1.0 ↗ a+b complex topology › Aha1/BPI domain-like › Aha1/BPI domain-like › Aha1/BPI domain-like 0.60 53.0 4.30e-01 95.5% 77.1%
3482862 10.1.1.17 ↗ beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases › Laminin_G_2 0.60 47.0 3.63e-01 82.7% 66.3%
5039554 109.2.1.12 ↗ alpha superhelices › Repetitive alpha hairpins › alpha/alpha toroid › alpha/alpha toroid › Glyco_hydro_65m 0.60 47.0 2.79e-01 82.7% 22.0%
3839454 5084.5.1.25 ↗ beta barrels › Outer membrane meander beta-barrels › Porins › Porin › HP_OMP_2 0.60 47.0 3.14e-01 83.6% 40.9%
3198929 331.4.1.3 ↗ a+b two layers › TBP-like › Kinase associated domain 1, KA1 › Kinase associated domain 1, KA1 › AdenylateSensor 0.59 45.0 4.17e-01 80.0% 77.5%
3599997 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.59 45.0 2.66e-01 80.9% 17.2%
3699292 2004.1.1.198 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23 0.59 45.0 3.78e-01 80.9% 84.3%
3712649 2004.1.1.199 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23,SbcC_Walker_B 0.58 45.0 2.89e-01 80.9% 30.7%
4046546 12.3.1.6 ↗ beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich › Bgal_small_N 0.58 47.0 3.42e-01 86.4% 82.0%
3371113 9.23.1.0 ↗ beta barrels › Lipocalins/Streptavidin › Hypothetical protein BT_0869 › Hypothetical protein BT_0869 0.58 44.0 3.72e-01 88.2% 48.9%
4990953 3692.1.1.0 ↗ a+b two layers › Ornithine cyclodeaminase-like enzymes dimerization domain › Ornithine cyclodeaminase-like enzymes dimerization domain › Ornithine cyclodeaminase-like enzymes dimerization domain 0.58 48.0 4.59e-01 98.2% 78.2%
5045102 331.1.1.0 ↗ a+b two layers › TBP-like › TATA-box binding protein-like › TATA-box binding protein-like 0.58 45.0 4.89e-01 89.1% 94.7%
3170622 2004.1.1.199 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23,SbcC_Walker_B 0.58 40.0 2.35e-01 70.9% 14.9%
3993127 5.1.4.0 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.57 44.0 2.91e-01 80.9% 28.7%
3263284 12.3.1.46 ↗ beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich › ComC_SSD 0.57 45.0 3.47e-01 82.7% 81.7%
3987311 7579.1.1.27 ↗ a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › AXE1 0.57 46.0 3.31e-01 85.5% 53.3%
3878170 5.1.4.549 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › PF28327 0.57 43.0 3.01e-01 78.2% 95.4%
4029739 9.8.1.1 ↗ beta barrels › Lipocalins/Streptavidin › Dipeptidyl peptidase I (cathepsin C), exclusion domain › Dipeptidyl peptidase I (cathepsin C), exclusion domain › CathepsinC_exc 0.56 49.0 4.75e-01 92.7% 85.0%
4476440 2004.1.1.1156 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_15, AAA_23, SbcC_Walker_B 0.56 44.0 3.06e-01 82.7% 39.0%
4961667 5084.1.1.45 ↗ beta barrels › Outer membrane meander beta-barrels › OMPA-like › OMPA-like › PF26421 0.56 45.0 4.46e-01 93.6% 82.6%
5041496 12.3.1.0 ↗ beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich 0.56 45.0 3.34e-01 85.5% 77.0%
5048351 243.1.1.18 ↗ a+b two layers › Cystatin-like › NTF2-like › NTF2-like › SnoaL_2 0.55 38.0 3.57e-01 72.7% 63.4%
3169657 4099.1.1.47 ↗ a+b two layers › Kinetochore globular domain-like › Kinetochore globular domain-like › Kinetochore globular domain-like › PF30282 0.55 43.0 4.25e-01 83.6% 80.0%
4991720 3692.1.1.0 ↗ a+b two layers › Ornithine cyclodeaminase-like enzymes dimerization domain › Ornithine cyclodeaminase-like enzymes dimerization domain › Ornithine cyclodeaminase-like enzymes dimerization domain 0.55 47.0 4.52e-01 97.3% 82.4%
3229268 3369.1.1.0 ↗ beta meanders › lysosome-associated membrane protein LAMP-3 › lysosome-associated membrane protein LAMP-3 › lysosome-associated membrane protein LAMP-3 0.54 47.0 4.10e-01 98.2% 76.0%
3352272 331.9.1.2 ↗ a+b two layers › TBP-like › Subdomain of clathrin and coatomer appendage domain › Subdomain of clathrin and coatomer appendage domain › B2-adapt-app_C 0.54 43.0 4.27e-01 85.5% 100.0%
3703242 331.9.1.0 ↗ a+b two layers › TBP-like › Subdomain of clathrin and coatomer appendage domain › Subdomain of clathrin and coatomer appendage domain 0.54 42.0 4.15e-01 96.4% 76.7%
4012048 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.54 41.0 2.86e-01 80.9% 43.4%
3845580 59.1.1.15 ↗ beta complex topology › triple barrel › triple barrel › Rap30/74 interaction domains-like › ELL 0.53 41.0 3.99e-01 82.7% 78.4%
4176400 274.1.1.0 ↗ a+b two layers › Pili subunits › Pili subunits › Pili subunits 0.53 35.0 3.97e-01 95.5% 97.3%
3711273 331.9.1.0 ↗ a+b two layers › TBP-like › Subdomain of clathrin and coatomer appendage domain › Subdomain of clathrin and coatomer appendage domain 0.53 42.0 4.20e-01 96.4% 80.7%
3727346 12.3.1.19 ↗ beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich › Gal_mutarotas_2 0.52 43.0 3.07e-01 90.9% 95.4%
3968696 222.1.1.4 ↗ a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › 4HBT 0.52 37.0 3.22e-01 73.6% 66.7%
3345243 331.3.1.3 ↗ a+b two layers › TBP-like › Bet v1-like › Bet v1-like › START 0.52 43.0 3.41e-01 91.8% 98.3%
3653398 331.9.1.10 ↗ a+b two layers › TBP-like › Subdomain of clathrin and coatomer appendage domain › Subdomain of clathrin and coatomer appendage domain › PF28631 0.52 44.0 3.90e-01 90.9% 96.8%
5009702 331.3.1.0 ↗ a+b two layers › TBP-like › Bet v1-like › Bet v1-like 0.51 44.0 4.12e-01 94.5% 95.7%
3270919 331.9.1.2 ↗ a+b two layers › TBP-like › Subdomain of clathrin and coatomer appendage domain › Subdomain of clathrin and coatomer appendage domain › B2-adapt-app_C 0.51 41.0 4.04e-01 97.3% 80.9%
3288281 881.1.1.15 ↗ a+b three layers › Mog1p/PsbP-like › Mog1p/PsbP-like › Mog1p/PsbP-like › DUF3558 0.51 40.0 3.71e-01 85.5% 96.5%
4113988 12.3.1.2 ↗ beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich › Cu_amine_oxid 0.51 40.0 2.68e-01 82.7% 61.2%
D3 medium residues 312-404
PDB
Domain cluster: representative
CATH (14)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2w96A02 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.66 47.0 4.46e-01 75.3% 65.5%
3ipiA00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.60 42.0 3.10e-01 73.1% 40.3%
1f4qA00 1.10.238.10 Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › EF-hand 0.59 43.0 3.64e-01 77.4% 45.3%
1jr8A00 1.20.120.310 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › ERV/ALR sulfhydryl oxidase domain 0.58 42.0 4.11e-01 78.5% 67.6%
3gwlA00 1.20.120.310 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › ERV/ALR sulfhydryl oxidase domain 0.58 42.0 4.07e-01 78.5% 67.0%
1aj4A00 1.10.238.10 Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › EF-hand 0.56 37.0 3.17e-01 75.3% 40.0%
1uurA03 1.10.238.10 Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › EF-hand 0.55 42.0 4.33e-01 82.8% 87.5%
3o3mB01 1.20.1270.370 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.55 37.0 3.60e-01 77.4% 62.1%
3cexA00 1.20.120.450 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › dinb family like domain 0.54 39.0 3.21e-01 76.3% 57.6%
2fyfA02 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.53 40.0 3.90e-01 80.6% 97.1%
4yzrA00 1.10.630.10 Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 0.52 39.0 2.59e-01 80.6% 34.8%
1f1mA00 1.20.120.240 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Lipoprotein, type 6 0.51 40.0 3.40e-01 86.0% 63.0%
6bldA00 1.10.630.10 Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 0.51 39.0 2.54e-01 80.6% 31.9%
8bs9A01 3.90.70.10 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Cysteine proteinases 0.50 44.0 3.16e-01 100.0% 40.7%
ECOD (12)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3923539 101.1.10.1 ↗ alpha arrays › HTH › HTH › Cyclin-like › Cyclin_N 0.66 47.0 4.08e-01 75.3% 55.9%
3279344 2007.5.1.15 ↗ a/b three-layered sandwiches › Flavodoxin-like › SGNH hydrolase › SGNH hydrolase › FkbH_N 0.63 47.0 3.44e-01 78.5% 87.1%
3781291 192.2.1.1 ↗ alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 0.62 31.0 3.05e-01 77.4% 44.0%
3742966 601.21.1.1 ↗ alpha bundles › Four-helical up-and-down bundle › FAD-dependent thiol oxidase › FAD-dependent thiol oxidase › Evr1_Alr 0.62 45.0 4.27e-01 78.5% 64.5%
3591990 6076.1.1.0 ↗ alpha arrays › Catalytic cysteine domain in ubiquitin-activating enzyme › Catalytic cysteine domain in ubiquitin-activating enzyme › Catalytic cysteine domain in ubiquitin-activating enzyme 0.59 43.0 3.37e-01 77.4% 64.4%
3287020 3997.1.1.1 ↗ alpha arrays › Helical insertion domain in magnesium chelatase catalytic subunit › Helical insertion domain in magnesium chelatase catalytic subunit › Helical insertion domain in magnesium chelatase catalytic subunit › CobN-Mg_chel 0.55 43.0 3.39e-01 83.9% 56.5%
5012928 4044.1.1.0 ↗ alpha bundles › Helical bundle domain in prismane-like proteins › Helical bundle domain in prismane-like proteins › Helical bundle domain in prismane-like proteins 0.54 39.0 3.81e-01 75.3% 100.0%
3727319 601.1.1.77 ↗ alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › DUF3176 0.52 38.0 3.09e-01 76.3% 79.5%
3236857 193.1.1.1 ↗ alpha bundles › CH domain-like › Calponin-homology domain-like › Calponin-homology domain-like › CH 0.51 36.0 3.26e-01 74.2% 76.3%
3676439 219.1.1.3 ↗ a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › UCH 0.51 45.0 3.07e-01 100.0% 38.6%
3706689 327.11.2.0 ↗ a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) 0.51 35.0 3.86e-01 71.0% 100.0%
4837383 223.3.1.3 ↗ a+b three layers › Profilin-like › a+b domain in beta-lactamase/transpeptidase-like proteins › a+b domain in beta-lactamase/transpeptidase-like proteins › Transpeptidase 0.50 37.0 3.38e-01 81.7% 59.7%
D4 medium residues 532-587
PDB
Domain cluster: representative
CATH (44)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3f2bA05 6.10.50.10 Special › Helix non-globular › Insulin-like, subunit E › 0.84 56.0 6.06e-01 76.8% 81.2%
2ktmA00 1.10.790.10 Mainly Alpha › Orthogonal Bundle › Major Prion Protein › Prion/Doppel protein, beta-ribbon domain 0.82 62.0 5.87e-01 83.9% 67.6%
2dt5B01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.77 52.0 4.73e-01 71.4% 53.4%
3ufeA02 1.20.58.1950 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.75 60.0 6.18e-01 100.0% 90.6%
1hlvA02 1.10.10.60 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like 0.75 51.0 5.04e-01 71.4% 70.0%
1a3qA01 2.60.40.340 Mainly Beta › Sandwich › Immunoglobulin-like › Rel homology domain (RHD), DNA-binding domain 0.73 53.0 3.72e-01 78.6% 24.6%
4hteA02 1.20.58.1740 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.72 51.0 3.97e-01 75.0% 46.2%
6ldiF01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.72 62.0 5.26e-01 100.0% 62.5%
1gvfB00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.71 60.0 3.89e-01 100.0% 86.9%
5u4nA00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.70 60.0 3.71e-01 100.0% 83.7%
1l1lA01 3.20.70.20 Alpha Beta › Alpha-Beta Barrel › Anaerobic Ribonucleotide-triphosphate Reductase Large Chain › 0.70 59.0 3.48e-01 100.0% 17.0%
6ofuA00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.69 61.0 3.93e-01 100.0% 86.1%
4hr1A00 1.20.1270.410 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.69 52.0 4.06e-01 80.4% 93.2%
3byiD00 1.10.555.10 Mainly Alpha › Orthogonal Bundle › Phosphatidylinositol 3-kinase; Chain A › Rho GTPase activation protein 0.69 51.0 3.41e-01 78.6% 22.5%
1sg7A00 1.10.1740.70 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › ChaB 0.67 56.0 5.20e-01 100.0% 81.3%
1is8A01 1.10.286.10 Mainly Alpha › Orthogonal Bundle › GTP Cyclohydrolase I; Chain A, domain 1 › GTP cyclohydrolase I, N-terminal domain 0.67 51.0 5.04e-01 85.7% 85.0%
4i8oA03 1.10.8.1130 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Bacterial toxin RNase RnlA/LsoA, C-terminal Dmd-binding domain 0.67 57.0 5.44e-01 96.4% 88.1%
4evxA00 1.10.1740.240 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › 0.67 55.0 4.76e-01 100.0% 92.8%
3nbxX03 1.20.58.1510 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.66 50.0 4.06e-01 80.4% 68.3%
4akgA08 1.10.472.130 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Dynein motor, AAA2 domain, small subdomain 0.65 54.0 4.07e-01 100.0% 46.8%
5mmjo00 1.10.287.10 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › S15/NS1, RNA-binding 0.65 47.0 4.26e-01 75.0% 68.0%
3vayA02 1.20.120.1600 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.65 55.0 4.86e-01 100.0% 70.1%
2i2xB01 1.10.1240.10 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain 0.65 47.0 3.92e-01 78.6% 54.0%
7qaqA01 3.40.50.11710 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Cyclodipeptide synthase 0.65 53.0 3.56e-01 91.1% 43.2%
2hszA02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.65 45.0 4.18e-01 73.2% 56.0%
8d7hD01 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.65 54.0 3.71e-01 89.3% 89.6%
2q14B01 1.10.3210.10 Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432 0.64 55.0 3.71e-01 100.0% 54.1%
1vx7301 1.10.287.310 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.64 50.0 4.48e-01 82.1% 67.6%
2mtqA00 1.20.58.130 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.64 45.0 4.14e-01 75.0% 64.4%
1knzA01 6.10.280.20 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Rotavirus non-structural protein NSP3, N-terminal domain 0.64 47.0 3.96e-01 82.1% 48.0%
8igrI01 2.40.270.10 Mainly Beta › Beta Barrel › Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; Domain 6 › DNA-directed RNA polymerase, subunit 2, domain 6 0.63 53.0 3.68e-01 91.1% 38.6%
1t72A02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.63 48.0 3.98e-01 80.4% 70.4%
1sumB01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.62 47.0 3.81e-01 82.1% 66.4%
3axjB02 1.20.58.200 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 0.60 45.0 3.90e-01 80.4% 61.2%
1nv8B01 1.10.8.10 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain 0.60 52.0 4.83e-01 100.0% 84.5%
1yfmA01 1.10.275.10 Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › Fumarase/aspartase (N-terminal domain) 0.60 51.0 4.02e-01 100.0% 54.8%
3t0yA01 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.59 49.0 4.69e-01 94.6% 83.3%
2kg7B00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.59 43.0 3.61e-01 78.6% 52.6%
1rc2A00 1.20.1080.10 Mainly Alpha › Up-down Bundle › Glycerol uptake facilitator protein › Glycerol uptake facilitator protein. 0.58 51.0 3.37e-01 98.2% 49.8%
2qupA00 1.20.120.490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hypothetical protein TM1646-like domain 0.57 50.0 3.88e-01 96.4% 53.8%
2jaeA03 1.20.1440.240 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.55 42.0 3.42e-01 80.4% 79.2%
1xwjA01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.54 48.0 3.64e-01 98.2% 53.8%
3rqtA02 3.10.105.10 Alpha Beta › Roll › Dipeptide-binding Protein; domain 3 › Dipeptide-binding Protein; Domain 3 0.54 48.0 3.23e-01 100.0% 70.4%
6f1eA01 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.51 46.0 3.36e-01 96.4% 51.8%
ECOD (49)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4014515 148.1.3.0 ↗ alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.83 75.0 6.25e-01 100.0% 73.7%
4579131 140.1.1.11 ↗ alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › DALR_1 0.81 63.0 4.11e-01 83.9% 21.0%
5055976 4126.1.1.1 ↗ a/b three-layered sandwiches › beta-carbonic anhydrase-like › beta-carbonic anhydrase › beta-carbonic anhydrase › Pro_CA 0.80 70.0 4.65e-01 94.6% 59.0%
5082532 148.1.3.0 ↗ alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.80 59.0 5.45e-01 78.6% 62.9%
3811948 616.1.1.0 ↗ alpha arrays › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain 0.75 58.0 5.38e-01 83.9% 72.9%
4610257 6130.1.1.0 ↗ alpha complex topology › Selenocysteine synthase N-terminal domain › Selenocysteine synthase N-terminal domain › Selenocysteine synthase N-terminal domain 0.74 65.0 6.21e-01 100.0% 83.1%
3690556 148.1.1.0 ↗ alpha arrays › Histone-like › Histone-related › Histone 0.74 57.0 5.61e-01 85.7% 85.0%
4526829 6130.1.1.1 ↗ alpha complex topology › Selenocysteine synthase N-terminal domain › Selenocysteine synthase N-terminal domain › Selenocysteine synthase N-terminal domain › Se-cys_synth_N 0.74 65.0 5.97e-01 100.0% 81.3%
4488191 191.1.1.0 ↗ alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain 0.73 58.0 4.61e-01 87.5% 91.3%
3623206 3567.1.1.10 ↗ a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer › MEIOC 0.73 53.0 3.63e-01 76.8% 77.3%
3826019 633.22.1.0 ↗ alpha bundles › Bromodomain-like › Vitamin K epoxide reductase (VKOR) › Vitamin K epoxide reductase (VKOR) 0.72 52.0 3.57e-01 76.8% 66.8%
3592370 150.5.1.0 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like 0.72 57.0 4.52e-01 89.3% 57.5%
4876272 142.1.1.3 ↗ alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › Sigma70_r2 0.71 62.0 5.23e-01 100.0% 61.9%
3512559 192.1.1.37 ↗ alpha bundles › Long alpha-hairpin › GreA transcript cleavage protein, N-terminal domain › GreA transcript cleavage protein, N-terminal domain › DUF7753 0.71 55.0 5.25e-01 83.9% 73.8%
3913498 5054.1.1.0 ↗ alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels 0.71 52.0 3.86e-01 78.6% 72.1%
3531209 105.1.1.1 ↗ alpha duplicates or obligate multimers › HLH-like › HLH, helix-loop-helix DNA-binding domain › HLH, helix-loop-helix DNA-binding domain › HLH 0.70 54.0 4.98e-01 91.1% 65.7%
3935681 3664.1.1.0 ↗ alpha arrays › Small, acid-soluble spore protein C › Small, acid-soluble spore protein C › Small, acid-soluble spore protein C 0.68 53.0 5.57e-01 83.9% 100.0%
3345515 142.1.1.0 ↗ alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors 0.68 59.0 5.09e-01 100.0% 84.4%
3807996 616.1.1.0 ↗ alpha arrays › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain 0.68 49.0 4.76e-01 85.7% 67.7%
3263465 192.15.1.0 ↗ alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains 0.67 46.0 4.20e-01 76.8% 51.2%
3990688 601.7.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain 0.67 53.0 4.40e-01 83.9% 53.7%
5072044 213.1.1.17 ↗ a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) › DUF1122 0.67 51.0 3.40e-01 82.1% 32.7%
3554564 5050.1.1.4 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Nucleoside_tran 0.67 55.0 3.55e-01 89.3% 80.8%
4232288 4275.1.1.10 ↗ alpha arrays › Hypothetical protein YqbG-like › Hypothetical protein YqbG-like › Hypothetical protein YqbG-like › NifW 0.67 55.0 5.17e-01 96.4% 85.7%
3270778 108.1.1.96 ↗ alpha arrays › EF-hand › EF-hand-related › EF-hand › EF-hand_1, EF-hand_6, EF-hand_7 0.67 51.0 4.27e-01 83.9% 49.0%
5078040 5069.1.3.0 ↗ alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits 0.66 49.0 4.40e-01 83.9% 60.0%
3228511 601.1.2.0 ↗ alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) 0.65 50.0 3.66e-01 82.1% 84.7%
4527514 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.65 44.0 2.76e-01 71.4% 21.1%
3481547 101.1.2.68 ↗ alpha arrays › HTH › HTH › winged helix domain › RNA_pol_Rpc34 0.64 55.0 4.00e-01 94.6% 42.7%
3530843 192.29.1.0 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.64 46.0 3.55e-01 75.0% 60.8%
3912255 194.1.1.3 ↗ alpha complex topology › Serum albumin-like › Serum albumin-like › Serum albumin-like › ECM1 0.64 56.0 4.06e-01 96.4% 77.0%
3709879 181.1.1.0 ↗ alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins 0.63 52.0 4.87e-01 100.0% 81.3%
5081190 5059.1.1.1 ↗ alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA 0.63 49.0 3.69e-01 83.9% 42.2%
5058952 138.1.1.38 ↗ alpha arrays › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › MutL_C 0.63 47.0 4.69e-01 92.9% 80.0%
4938848 5069.1.3.131 ↗ alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › DUF92 0.63 55.0 4.57e-01 100.0% 66.0%
5063967 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.63 45.0 4.41e-01 76.8% 70.0%
3221764 603.2.1.0 ↗ alpha bundles › STAT-like › STAT › STAT 0.62 46.0 4.11e-01 78.6% 63.7%
4623302 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.62 52.0 3.52e-01 100.0% 31.2%
3664940 192.4.1.22 ↗ alpha bundles › Long alpha-hairpin › Ribosomal protein L29 (L29p) › Ribosomal protein L29 (L29p) › PF26575 0.62 44.0 3.97e-01 76.8% 62.5%
3393952 7515.1.1.6 ↗ a/b three-layered sandwiches › Alkaline phosphatase-like › Alkaline phosphatase-like › Alkaline phosphatase-like › Phosphodiest 0.61 51.0 3.14e-01 94.6% 85.1%
4960130 148.1.3.0 ↗ alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.61 53.0 4.58e-01 100.0% 64.4%
5040466 604.3.1.0 ↗ alpha bundles › Spectrin repeat-like › BAG domain › BAG domain 0.60 45.0 4.15e-01 80.4% 71.6%
4991162 2484.1.1.302 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB 0.60 52.0 3.41e-01 92.9% 58.6%
3592177 604.3.1.1 ↗ alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › BAG 0.59 45.0 4.18e-01 80.4% 74.3%
3290838 192.29.1.0 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.59 49.0 4.03e-01 100.0% 56.5%
3703277 604.3.1.0 ↗ alpha bundles › Spectrin repeat-like › BAG domain › BAG domain 0.57 43.0 4.06e-01 80.4% 75.7%
3499253 174.1.1.75 ↗ few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Otopetrin 0.56 45.0 2.97e-01 91.1% 73.7%
3481731 148.1.1.18 ↗ alpha arrays › Histone-like › Histone-related › Histone › CENP-S 0.54 47.0 3.94e-01 96.4% 77.9%
3644495 7022.1.1.0 ↗ alpha bundles › central core domain of D-alanyl transfer protein › central core domain of D-alanyl transfer protein › central core domain of D-alanyl transfer protein 0.53 48.0 3.66e-01 100.0% 55.2%