Back to structures

SRR1747019_scaffold_113_prodigal-single.1__X__X__00030

Bact-Vir

SRR1747019_scaffold_113_prodigal-single.1__X__X__00030

Identity

Kingdom:
phage

Quality

83.4 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 68-175_465-515
PDB
Domain cluster: representative
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF16592.11 best Cas9_REC 27.5 2.00e-06 62.3% 8.1%
PF16593.12 Cas9-BH 39.3 5.70e-10 17.0% 78.8%
CATH (6)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4al0A00 1.20.120.550 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Membrane associated eicosanoid/glutathione metabolism-like domain 0.60 33.0 3.42e-01 84.9% 56.2%
1jr8A00 1.20.120.310 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › ERV/ALR sulfhydryl oxidase domain 0.59 28.0 3.35e-01 84.3% 64.8%
4h8aB01 1.10.1530.10 Mainly Alpha › Orthogonal Bundle › Hypothetical Oxidoreductase Yiak; Chain: A, domain 1 › Malate/L-lactate/L-sulpholactate dehydrogenase, four-helix barrel 0.53 21.0 3.11e-01 76.7% 88.3%
6zhiB02 1.20.1270.10 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.52 25.0 3.28e-01 79.2% 84.3%
1b68A00 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.51 33.0 3.57e-01 81.1% 74.6%
3di2A00 1.20.1250.50 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.51 27.0 3.07e-01 100.0% 67.8%
ECOD (6)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4861007 3819.1.1.2 alpha complex topology › CRISPR-associated endonuclease Cas9 alpha-helical lobe › CRISPR-associated endonuclease Cas9 alpha-helical lobe › CRISPR-associated endonuclease Cas9 alpha-helical lobe 0.88 86.0 6.99e-01 100.0% 96.5%
2511942 3819.1.1.2 alpha complex topology › CRISPR-associated endonuclease Cas9 alpha-helical lobe › CRISPR-associated endonuclease Cas9 alpha-helical lobe › CRISPR-associated endonuclease Cas9 alpha-helical lobe 0.87 85.0 5.36e-01 100.0% 57.5%
5002309 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.61 36.0 3.48e-01 100.0% 51.4%
3304829 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.51 37.0 3.63e-01 100.0% 69.0%
4941988 180.1.1.1 alpha bundles › Acid phosphatase/Vanadium-dependent haloperoxidase › Acid phosphatase/Vanadium-dependent haloperoxidase › Acid phosphatase/Vanadium-dependent haloperoxidase › PAP2 0.51 35.0 3.65e-01 100.0% 75.2%
3857195 109.4.1.1578 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF30504 0.51 36.0 3.24e-01 73.6% 73.5%
D2 high residues 187-333
PDB
Domain cluster: representative
CATH (6)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1cnt200 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.67 38.0 4.05e-01 100.0% 62.3%
2btdA00 1.25.40.340 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › DhaL domain 0.60 53.0 4.73e-01 97.3% 95.7%
1aepA00 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.58 42.0 4.17e-01 100.0% 71.2%
3f2eA00 1.20.58.800 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.57 33.0 4.21e-01 99.3% 100.0%
3vkgA18 1.10.8.720 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Region D6 of dynein motor 0.52 43.0 4.11e-01 89.1% 91.3%
4y2fA00 3.30.450.40 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › GAF domain 0.52 42.0 4.34e-01 99.3% 89.5%
ECOD (2)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3216092 3930.1.1.0 alpha bundles › Helical bundle insertion in helicase domains › Helical bundle in Hef helicase › Helical bundle in Hef helicase 0.60 38.0 3.91e-01 100.0% 64.8%
3814874 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.51 36.0 3.40e-01 72.8% 86.1%
D3 high residues 570-740
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF16592.11 best Cas9_REC 79.3 4.10e-22 100.0% 32.1%
ECOD (18)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
2511942 3819.1.1.2 alpha complex topology › CRISPR-associated endonuclease Cas9 alpha-helical lobe › CRISPR-associated endonuclease Cas9 alpha-helical lobe › CRISPR-associated endonuclease Cas9 alpha-helical lobe 0.85 82.0 5.31e-01 100.0% 26.3%
4922640 2484.1.1.238 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas9_REC 0.85 47.0 5.09e-01 83.6% 63.5%
4922668 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.84 46.0 5.02e-01 83.6% 63.5%
4869022 3819.1.1.1 alpha complex topology › CRISPR-associated endonuclease Cas9 alpha-helical lobe › CRISPR-associated endonuclease Cas9 alpha-helical lobe › CRISPR-associated endonuclease Cas9 alpha-helical lobe › Cas9_REC 0.83 54.0 5.75e-01 78.4% 73.4%
1684073 3819.1.1.0 alpha complex topology › CRISPR-associated endonuclease Cas9 alpha-helical lobe › CRISPR-associated endonuclease Cas9 alpha-helical lobe › CRISPR-associated endonuclease Cas9 alpha-helical lobe 0.80 76.0 5.68e-01 100.0% 47.4%
4851841 3819.1.1.3 alpha complex topology › CRISPR-associated endonuclease Cas9 alpha-helical lobe › CRISPR-associated endonuclease Cas9 alpha-helical lobe › CRISPR-associated endonuclease Cas9 alpha-helical lobe › Cas9_a 0.74 70.0 6.61e-01 100.0% 93.5%
3387670 3819.1.1.0 alpha complex topology › CRISPR-associated endonuclease Cas9 alpha-helical lobe › CRISPR-associated endonuclease Cas9 alpha-helical lobe › CRISPR-associated endonuclease Cas9 alpha-helical lobe 0.74 70.0 5.20e-01 100.0% 44.9%
2550471 3819.1.1.3 alpha complex topology › CRISPR-associated endonuclease Cas9 alpha-helical lobe › CRISPR-associated endonuclease Cas9 alpha-helical lobe › CRISPR-associated endonuclease Cas9 alpha-helical lobe › Cas9_a 0.74 69.0 5.14e-01 100.0% 47.3%
3058754 3819.1.1.0 alpha complex topology › CRISPR-associated endonuclease Cas9 alpha-helical lobe › CRISPR-associated endonuclease Cas9 alpha-helical lobe › CRISPR-associated endonuclease Cas9 alpha-helical lobe 0.72 67.0 5.12e-01 100.0% 48.5%
3554793 592.1.1.0 alpha arrays › PWI domain-like › PWI domain › PWI domain 0.70 31.0 4.61e-01 87.7% 94.7%
3468254 592.2.1.0 alpha arrays › PWI domain-like › YugE-like › YugE-like 0.70 30.0 4.64e-01 87.1% 100.0%
3992442 592.7.1.1 alpha arrays › PWI domain-like › GIPC1 GH2 domain › GIPC1 GH2 domain › GIPC1_GH2 0.70 33.0 4.59e-01 90.6% 90.6%
3266110 592.7.1.0 alpha arrays › PWI domain-like › GIPC1 GH2 domain › GIPC1 GH2 domain 0.69 30.0 4.36e-01 86.5% 88.7%
3258043 3919.1.1.2 alpha duplicates or obligate multimers › N-terminal domain of COMMD9 › N-terminal domain of COMMD9 › N-terminal domain of COMMD9 › COMM_HN 0.58 31.0 3.76e-01 88.3% 77.3%
3550609 3919.1.1.2 alpha duplicates or obligate multimers › N-terminal domain of COMMD9 › N-terminal domain of COMMD9 › N-terminal domain of COMMD9 › COMM_HN 0.57 32.0 3.82e-01 90.1% 80.0%
3251428 3919.1.1.4 alpha duplicates or obligate multimers › N-terminal domain of COMMD9 › N-terminal domain of COMMD9 › N-terminal domain of COMMD9 › COMMD1_N 0.54 31.0 3.75e-01 88.9% 85.5%
1883360 1101.1.1.1 alpha bundles › Uncharacterized protein LPG2271 › Uncharacterized protein LPG2271 › Uncharacterized protein LPG2271 › DUF5638 0.54 30.0 3.73e-01 85.4% 86.9%
4397698 3919.1.1.2 alpha duplicates or obligate multimers › N-terminal domain of COMMD9 › N-terminal domain of COMMD9 › N-terminal domain of COMMD9 › COMM_HN 0.51 30.0 3.47e-01 94.2% 79.2%
D4 high residues 854-999
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF13395.13 best HNH_4 71.2 7.40e-20 36.3% 96.3%
CATH (2)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2hxiB02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.54 29.0 2.99e-01 81.5% 53.0%
4g2aA02 1.20.58.1690 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.51 27.0 3.35e-01 74.7% 82.8%
ECOD (14)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
2859872 378.1.1.10 few secondary structure elements › His-Me finger endonucleases › His-Me finger endonucleases › His-Me finger endonucleases › HNH_4 0.84 75.0 6.79e-01 100.0% 72.5%
2991844 378.1.1.10 few secondary structure elements › His-Me finger endonucleases › His-Me finger endonucleases › His-Me finger endonucleases › HNH_4 0.83 59.0 6.89e-01 74.0% 98.2%
3950953 377.1.1.78 few secondary structure elements › Glucocorticoid receptor-like › LIM domain-like › LIM domain-like › HNH_5 0.81 40.0 5.76e-01 93.2% 100.0%
3277754 377.1.1.88 few secondary structure elements › Glucocorticoid receptor-like › LIM domain-like › LIM domain-like › HNH 0.81 40.0 5.73e-01 90.4% 100.0%
2550470 378.1.1.10 few secondary structure elements › His-Me finger endonucleases › His-Me finger endonucleases › His-Me finger endonucleases › HNH_4 0.79 60.0 5.71e-01 78.1% 78.3%
3952818 378.1.1.27 few secondary structure elements › His-Me finger endonucleases › His-Me finger endonucleases › His-Me finger endonucleases › HNH_5 0.78 40.0 5.66e-01 88.4% 100.0%
1684075 378.1.1.10 few secondary structure elements › His-Me finger endonucleases › His-Me finger endonucleases › His-Me finger endonucleases › HNH_4 0.71 66.0 6.30e-01 100.0% 85.6%
2663386 378.1.1.10 few secondary structure elements › His-Me finger endonucleases › His-Me finger endonucleases › His-Me finger endonucleases › HNH_4 0.70 66.0 6.24e-01 100.0% 86.4%
4943720 378.1.1.0 few secondary structure elements › His-Me finger endonucleases › His-Me finger endonucleases › His-Me finger endonucleases 0.65 46.0 5.00e-01 73.3% 97.6%
4966182 378.1.1.9 few secondary structure elements › His-Me finger endonucleases › His-Me finger endonucleases › His-Me finger endonucleases › HNH_2 0.64 47.0 4.99e-01 74.7% 100.0%
3948700 378.1.1.9 few secondary structure elements › His-Me finger endonucleases › His-Me finger endonucleases › His-Me finger endonucleases › HNH_2 0.64 46.0 4.93e-01 73.3% 96.0%
3587782 378.1.1.0 few secondary structure elements › His-Me finger endonucleases › His-Me finger endonucleases › His-Me finger endonucleases 0.55 40.0 4.53e-01 80.1% 99.1%
None 0.53 46.0 4.67e-01 98.6% 93.1%
4981807 378.1.1.9 few secondary structure elements › His-Me finger endonucleases › His-Me finger endonucleases › His-Me finger endonucleases › HNH_2 0.51 45.0 4.48e-01 97.3% 97.4%
D5 medium residues 1-67_1120-1160
PDB
Domain cluster: representative
CATH (6)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2nvnA00 2.30.31.10 Mainly Beta › Roll › Transcriptional Co-activator pc4; Chain A › Transcriptional Coactivator Pc4; Chain A 0.58 28.0 2.76e-01 89.8% 41.7%
1tr8A01 2.20.70.30 Mainly Beta › Single Sheet › Ubiquitin Ligase Nedd4; Chain: W; › Nascent polypeptide-associated complex domain 0.57 24.0 3.19e-01 82.4% 73.1%
5fgoA00 3.10.450.700 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.57 24.0 3.05e-01 97.2% 64.5%
2it9A00 2.30.31.10 Mainly Beta › Roll › Transcriptional Co-activator pc4; Chain A › Transcriptional Coactivator Pc4; Chain A 0.54 28.0 2.75e-01 88.9% 45.0%
2mhgA00 2.20.130.30 Mainly Beta › Single Sheet › S-adenosyl-L-methionine-dependent methyltransferases › Protein of unknown function DUF2782 0.53 29.0 3.33e-01 93.5% 74.7%
4v19S00 3.30.420.80 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribosomal protein S11/S14 0.50 28.0 2.61e-01 99.1% 42.0%
ECOD (7)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4315437 2484.1.1.97 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas9_RuvC 0.70 66.0 4.64e-01 99.1% 100.0%
4277444 2484.1.1.97 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas9_RuvC 0.69 65.0 4.67e-01 100.0% 98.6%
3263006 844.1.1.2 beta barrels › Transcriptional factor tubby, C-terminal domain › Transcriptional factor tubby, C-terminal domain › Transcriptional factor tubby, C-terminal domain › LOR 0.55 31.0 2.76e-01 100.0% 37.5%
5046458 844.1.1.2 beta barrels › Transcriptional factor tubby, C-terminal domain › Transcriptional factor tubby, C-terminal domain › Transcriptional factor tubby, C-terminal domain › LOR 0.53 33.0 2.79e-01 100.0% 37.1%
4324615 844.1.1.2 beta barrels › Transcriptional factor tubby, C-terminal domain › Transcriptional factor tubby, C-terminal domain › Transcriptional factor tubby, C-terminal domain › LOR 0.52 30.0 2.72e-01 100.0% 39.4%
4975453 844.1.1.2 beta barrels › Transcriptional factor tubby, C-terminal domain › Transcriptional factor tubby, C-terminal domain › Transcriptional factor tubby, C-terminal domain › LOR 0.52 31.0 2.74e-01 100.0% 37.9%
5038572 331.3.1.0 a+b two layers › TBP-like › Bet v1-like › Bet v1-like 0.50 32.0 2.89e-01 93.5% 46.0%
D6 medium residues 360-464
PDB
Domain cluster: representative
CATH (2)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2xcqA02 3.90.199.10 Alpha Beta › Alpha-Beta Complex › Topoisomerase II; domain 5 › Topoisomerase II, domain 5 0.54 47.0 3.57e-01 99.0% 87.5%
2luyA01 3.30.60.210 Alpha Beta › 2-Layer Sandwich › Wheat Germ Agglutinin (Isolectin 2); domain 1 › Stc1 domain 0.53 22.0 2.78e-01 72.4% 61.4%
D7 medium residues 741-790
PDB
Domain cluster: representative
ECOD (4)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3614778 223.1.1.0 a+b three layers › Profilin-like › sensor domains › sensor domains 0.55 39.0 2.95e-01 82.0% 55.5%
5044837 375.1.1.0 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.53 39.0 3.72e-01 80.0% 86.7%
5046198 375.1.1.0 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.53 39.0 3.80e-01 80.0% 94.5%
3741610 2485.1.1.0 a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like 0.50 35.0 2.43e-01 78.0% 76.8%
D8 medium residues 1308-1326_1350-1370_1380-1436
PDB
Domain cluster: representative
CATH (2)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3kyiA00 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.59 49.0 4.49e-01 91.8% 86.7%
2e9fB01 1.10.275.10 Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › Fumarase/aspartase (N-terminal domain) 0.52 40.0 4.11e-01 88.7% 85.4%