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SRR1747021_scaffold_4_curated_closed_complete_prodigal-single.1__X__X__00191

Bact-Vir

SRR1747021_scaffold_4_curated_closed_complete_prodigal-single.1__X__X__00191

Identity

Kingdom:
phage

Quality

64.7 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 6-128_155-188
PDB
CATH (29)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
6t0bf00 1.25.40.40 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Cytochrome c oxidase, subunit Va/VI 0.74 46.0 5.58e-01 81.5% 95.1%
4xriA00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.66 56.0 3.47e-01 89.2% 17.1%
3l9fA02 6.10.140.1570 Special › Helix non-globular › Helix Hairpins › 0.65 35.0 4.66e-01 74.5% 100.0%
3bwtA00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.65 46.0 3.53e-01 89.8% 33.9%
1xwjA01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.63 37.0 4.08e-01 79.0% 70.0%
3v5uA01 6.10.280.80 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › NCX, peripheral helical region 0.63 31.0 4.35e-01 95.5% 98.7%
3tjzB00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.62 44.0 3.68e-01 87.3% 42.4%
6xz3A01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.61 34.0 3.87e-01 78.3% 70.9%
1oyzA00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.61 43.0 3.57e-01 87.3% 41.0%
3vkgA02 1.20.140.100 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Dynein motor heavy chain, linker domain, N-terminal subdomain 0.61 32.0 3.32e-01 81.5% 53.1%
3swhA01 1.10.357.50 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › 0.60 44.0 4.37e-01 75.2% 90.3%
5h5mA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.60 35.0 3.82e-01 80.9% 68.5%
3qweA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.60 33.0 2.76e-01 95.5% 31.9%
2p61A00 1.20.120.490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hypothetical protein TM1646-like domain 0.59 32.0 3.66e-01 79.6% 70.2%
2xqyA02 1.20.58.1340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.58 41.0 4.34e-01 72.6% 99.3%
5l0wB01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.57 40.0 4.30e-01 86.0% 81.9%
1zvzA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.57 32.0 3.55e-01 79.6% 67.7%
1qdbA02 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.56 31.0 3.23e-01 94.3% 57.3%
7qx4A01 1.20.190.10 Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain 0.55 47.0 4.18e-01 93.6% 83.3%
5dllA05 1.25.50.10 Mainly Alpha › Alpha Horseshoe › Zincin-like fold › Peptidase M1, alanyl aminopeptidase, C-terminal domain 0.55 48.0 3.89e-01 98.1% 67.3%
6h2dS01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.54 41.0 3.63e-01 78.3% 89.7%
4f5cA04 1.25.50.20 Mainly Alpha › Alpha Horseshoe › Zincin-like fold › 0.54 48.0 3.82e-01 100.0% 85.5%
2lnlA00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.53 47.0 3.85e-01 98.1% 80.1%
7e84A02 1.20.120.350 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C 0.52 30.0 3.24e-01 96.8% 62.6%
1uddA00 1.20.910.10 Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like 0.52 37.0 3.35e-01 73.9% 100.0%
2w31A00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.51 37.0 3.83e-01 75.2% 81.6%
2iiuA00 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.51 45.0 4.09e-01 95.5% 98.6%
6orcB00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.51 34.0 3.67e-01 87.3% 78.4%
1h0oA00 1.10.620.20 Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A 0.50 41.0 3.42e-01 89.2% 87.5%
ECOD (43)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3664325 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.76 42.0 4.38e-01 77.1% 57.3%
3675551 109.4.1.189 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR_2 0.74 48.0 4.69e-01 84.1% 59.5%
3813216 109.4.1.1295 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, PPR_3, TPR_24 0.73 49.0 4.05e-01 86.6% 40.0%
3805054 109.4.1.775 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.72 48.0 4.66e-01 82.2% 61.2%
3303906 109.4.1.420 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR 0.71 46.0 4.89e-01 83.4% 74.1%
3738066 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.71 51.0 4.20e-01 86.0% 41.4%
3427290 109.4.1.189 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR_2 0.71 46.0 4.26e-01 84.7% 51.8%
3462648 109.4.1.1279 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_1, PPR_2, PPR_long, TPR_24 0.71 47.0 3.47e-01 81.5% 26.7%
3364203 109.4.1.240 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR_long 0.71 47.0 5.01e-01 84.7% 75.7%
3903382 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.71 53.0 4.96e-01 91.7% 63.7%
3806322 109.4.1.420 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR 0.71 45.0 5.14e-01 80.9% 86.1%
3338734 109.4.1.1258 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_1, PPR_2 0.70 46.0 5.21e-01 86.0% 86.7%
3648600 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.70 48.0 4.53e-01 83.4% 58.9%
3805216 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.69 47.0 4.76e-01 83.4% 68.1%
3664561 109.4.1.883 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR+PPR_2 0.69 46.0 4.15e-01 84.1% 48.6%
3665945 109.4.1.1257 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR_1, PPR_2 0.68 41.0 4.73e-01 70.7% 81.4%
3645209 109.4.1.1382 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_3, TPR_24 0.68 45.0 3.95e-01 85.4% 45.2%
3663500 109.4.1.1256 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, PPR_3 0.68 46.0 4.84e-01 84.7% 75.2%
3451478 109.4.1.1374 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, TPR_24 0.67 45.0 3.44e-01 84.1% 29.6%
3346105 109.4.1.420 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR 0.66 42.0 4.73e-01 83.4% 83.3%
3275145 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.66 54.0 3.54e-01 87.3% 35.4%
4020994 5069.1.1.0 ↗ alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes 0.62 32.0 3.38e-01 84.1% 53.1%
3422425 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.62 42.0 4.24e-01 83.4% 69.0%
4104235 109.4.1.158 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › ERAP1_C 0.62 57.0 4.47e-01 100.0% 87.8%
3994604 109.4.1.470 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › INTS2 0.61 48.0 4.04e-01 83.4% 48.7%
3604295 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.61 42.0 3.89e-01 70.1% 73.8%
3729738 109.4.1.158 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › ERAP1_C 0.61 56.0 4.40e-01 100.0% 88.4%
3272809 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.61 51.0 4.52e-01 89.8% 71.1%
3652793 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.60 51.0 4.47e-01 91.1% 79.1%
3561831 174.1.1.1 ↗ few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin 0.60 45.0 5.08e-01 100.0% 98.4%
3663038 109.4.1.420 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR 0.60 49.0 3.38e-01 86.6% 26.9%
3633839 109.4.1.22 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Adaptin_N 0.59 45.0 2.98e-01 85.4% 18.9%
3226081 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.59 46.0 3.25e-01 81.5% 29.4%
3748301 109.23.1.3 ↗ alpha superhelices › Repetitive alpha hairpins › C-terminal domain in vacuolar protein sorting-associated protein 54 › C-terminal domain in vacuolar protein sorting-associated protein 54 › BCD_RFX 0.59 45.0 4.60e-01 79.6% 86.5%
4929270 601.14.1.1 ↗ alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin › Hemerythrin 0.58 36.0 3.40e-01 80.3% 51.4%
4979165 601.14.1.1 ↗ alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin › Hemerythrin 0.58 37.0 3.53e-01 81.5% 55.6%
3411108 174.1.1.1 ↗ few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin 0.54 44.0 4.78e-01 100.0% 98.5%
3515944 109.4.1.443 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › MOR2-PAG1_C 0.53 44.0 3.46e-01 89.8% 43.9%
3249532 601.1.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.52 32.0 3.57e-01 77.7% 74.6%
4993201 604.5.1.1 ↗ alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div 0.51 44.0 3.94e-01 93.0% 94.5%
3562523 3755.4.1.0 ↗ alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.50 40.0 3.94e-01 83.4% 80.0%
3356747 109.4.1.1273 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_3 0.50 42.0 3.89e-01 94.3% 69.8%
5075639 150.1.1.0 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.50 41.0 4.37e-01 98.7% 99.3%
D2 high residues 198-289
PDB
CATH (17)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2mabA00 1.10.10.1350 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Spidroin domain, C-terminal domain 0.70 50.0 4.72e-01 73.9% 81.7%
2np5D00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.67 47.0 3.96e-01 72.8% 75.3%
5dckA00 1.10.1200.30 Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › Retrovirus capsid C-terminal domain 0.67 44.0 4.96e-01 100.0% 88.7%
3k59A07 1.10.132.60 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › B family DNA polymerase, thumb domain 0.66 50.0 4.36e-01 81.5% 100.0%
3f0cA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.63 49.0 4.35e-01 87.0% 74.3%
3dd7C00 1.20.120.1870 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Fic/DOC protein, Fido domain 0.59 47.0 4.29e-01 87.0% 81.1%
4lgvA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.58 42.0 3.31e-01 76.1% 42.3%
1z9hA03 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.57 48.0 4.14e-01 94.6% 92.7%
3umbA02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.57 37.0 3.99e-01 87.0% 77.2%
1oj6A00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.53 41.0 3.62e-01 87.0% 72.1%
1h6gA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.52 40.0 3.66e-01 82.6% 70.2%
1hbgA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.51 41.0 3.59e-01 89.1% 68.7%
1b5lA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.51 35.0 3.03e-01 71.7% 86.8%
1hxiA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.51 38.0 3.62e-01 100.0% 66.1%
4y6cA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.50 42.0 3.29e-01 100.0% 41.0%
6tkyA03 1.20.58.740 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › DOCK DHR2 domain, lobe C 0.50 42.0 3.97e-01 98.9% 100.0%
2qfcA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.50 42.0 3.07e-01 100.0% 31.0%
ECOD (19)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3601959 101.35.1.0 ↗ alpha arrays › HTH › DNA repair regulatory protein RecX › DNA repair regulatory protein RecX 0.68 52.0 4.92e-01 91.3% 69.1%
4624818 621.1.1.0 ↗ alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain 0.66 45.0 4.61e-01 70.7% 93.3%
3928372 304.48.1.1 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.64 54.0 3.39e-01 93.5% 23.9%
3859301 109.3.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.61 52.0 4.50e-01 94.6% 89.7%
2477784 3651.1.1.1 ↗ alpha bundles › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › IF-2B 0.61 48.0 4.64e-01 87.0% 86.1%
3918275 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.61 51.0 4.44e-01 94.6% 91.0%
3248344 1076.1.1.6 ↗ alpha bundles › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related › DUF2053 0.59 53.0 4.13e-01 100.0% 81.0%
3323493 170.1.1.15 ↗ alpha bundles › Retrovirus capsid protein › Retrovirus capsid protein-C › Retrovirus capsid protein-C › Retrotran_gag_2 0.57 47.0 4.33e-01 90.2% 70.8%
3579325 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.56 39.0 3.76e-01 98.9% 63.8%
3989520 5051.1.1.10 ↗ alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › AA_permease_2 0.55 47.0 3.05e-01 95.7% 87.2%
3844698 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.55 44.0 3.91e-01 100.0% 57.2%
3954931 5051.1.1.10 ↗ alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › AA_permease_2 0.55 43.0 2.77e-01 84.8% 76.0%
3463873 3807.1.1.4 ↗ alpha bundles › Yersinia protein kinase A (YpkA) Rho-GTPase binding domain › Yersinia protein kinase A (YpkA) Rho-GTPase binding domain › Yersinia protein kinase A (YpkA) Rho-GTPase binding domain › DUF4220 0.54 47.0 3.51e-01 100.0% 56.7%
3734988 109.4.1.747 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SGS 0.54 42.0 3.27e-01 100.0% 36.4%
3201335 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.53 43.0 3.52e-01 93.5% 60.5%
3756535 604.1.1.5 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin_3 0.52 38.0 3.60e-01 78.3% 84.3%
4956043 212.1.1.3 ↗ a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › GHMP_kinases_N 0.52 44.0 4.14e-01 100.0% 94.2%
3592328 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.51 44.0 3.23e-01 100.0% 44.4%
3592455 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.50 43.0 3.58e-01 97.8% 52.4%
D3 high residues 333-477
PDB
D4 high residues 510-624
PDB
D5 high residues 628-788
PDB
Domain cluster: representative
CATH (52)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2p61A00 1.20.120.490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hypothetical protein TM1646-like domain 0.73 39.0 4.67e-01 85.7% 74.6%
4rngC00 1.20.1280.290 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.73 39.0 5.20e-01 83.9% 98.8%
4qndA00 1.20.1280.290 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.71 41.0 5.14e-01 84.5% 92.8%
8alzB08 1.10.3380.10 Mainly Alpha › Orthogonal Bundle › Sec63 N-terminal domain-like fold › Sec63 N-terminal domain-like domain 0.71 38.0 4.21e-01 90.7% 63.4%
4f91B04 1.10.3380.10 Mainly Alpha › Orthogonal Bundle › Sec63 N-terminal domain-like fold › Sec63 N-terminal domain-like domain 0.71 39.0 4.14e-01 93.2% 59.9%
2qupA00 1.20.120.490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hypothetical protein TM1646-like domain 0.70 39.0 4.47e-01 85.7% 73.1%
3gs3A00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.70 55.0 4.71e-01 82.0% 55.0%
1wrdA00 1.20.58.160 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.68 38.0 4.79e-01 83.2% 89.8%
7ldgA00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.68 53.0 4.72e-01 85.1% 59.1%
2wb7A03 1.20.120.870 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › pT26-6p, five-helical bundle domain 0.67 39.0 4.28e-01 84.5% 68.4%
2katA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.66 38.0 4.41e-01 82.0% 78.3%
7qihA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.65 36.0 4.36e-01 78.9% 83.2%
4gycA00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.65 60.0 5.38e-01 100.0% 82.3%
3x3bA00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.64 59.0 4.96e-01 100.0% 77.1%
7q37A01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.64 59.0 5.37e-01 100.0% 83.6%
6gyhA00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.64 59.0 5.27e-01 100.0% 84.0%
3qmlD00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.64 44.0 3.67e-01 80.7% 40.7%
1bgfA00 1.10.532.10 Mainly Alpha › Orthogonal Bundle › Transcription Factor, Stat-4 › STAT transcription factor, N-terminal domain 0.63 36.0 4.11e-01 80.7% 72.6%
4gmnA00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.62 53.0 3.65e-01 91.9% 32.8%
5ewpA00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.61 50.0 4.36e-01 86.3% 84.2%
1n4kA02 1.25.10.30 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › IP3 receptor type 1 binding core, RIH domain 0.61 49.0 5.13e-01 85.7% 93.2%
2ot4A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.60 34.0 3.97e-01 83.9% 80.4%
2rasA01 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.59 41.0 3.89e-01 70.2% 82.2%
1yz5B00 1.20.190.20 Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › 14-3-3 domain 0.59 50.0 4.48e-01 92.5% 92.6%
1uw4B00 1.25.40.180 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.58 53.0 4.54e-01 97.5% 62.9%
4nwpD00 1.20.1200.10 Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like 0.58 47.0 4.95e-01 85.7% 98.0%
1jgcA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.56 44.0 4.49e-01 81.4% 81.2%
2v0pA00 1.25.40.540 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › TAP42-like family 0.56 44.0 4.03e-01 82.6% 97.7%
3r9mA00 1.25.40.280 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › alix/aip1 like domains 0.56 50.0 3.84e-01 97.5% 52.7%
3t9jA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.56 45.0 4.81e-01 85.1% 97.2%
1s3qG00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.56 45.0 4.54e-01 84.5% 84.7%
2qqyA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.56 42.0 4.55e-01 78.3% 89.9%
2gs4A00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.56 44.0 4.46e-01 81.4% 88.6%
1nfvA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.55 43.0 4.25e-01 81.4% 76.9%
2fjcB00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.55 42.0 4.31e-01 79.5% 85.9%
3unoE00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.55 43.0 4.25e-01 81.4% 77.8%
1zu2A00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.55 44.0 4.43e-01 98.1% 86.7%
1zs3A00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.54 42.0 4.11e-01 79.5% 78.4%
3e6sA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.54 42.0 4.30e-01 83.2% 87.4%
4cmyA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.54 42.0 4.27e-01 81.4% 80.4%
2vxxA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.54 42.0 4.15e-01 81.4% 81.4%
3gi8C00 1.20.1740.10 Mainly Alpha › Up-down Bundle › Amino acid/polyamine transporter I › Amino acid/polyamine transporter I 0.53 43.0 3.23e-01 87.6% 79.1%
3hiuD00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.53 43.0 4.42e-01 84.5% 89.5%
2c41C01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.53 40.0 4.21e-01 77.6% 87.9%
1d2tA00 1.20.144.10 Mainly Alpha › Up-down Bundle › Vanadium-containing Chloroperoxidase; domain 1 › Phosphatidic acid phosphatase type 2/haloperoxidase 0.53 38.0 3.49e-01 75.2% 66.2%
4c9bB00 1.25.40.180 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.52 49.0 4.03e-01 100.0% 67.9%
2chpA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.52 42.0 4.38e-01 85.1% 93.9%
1tjoB00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.52 42.0 4.14e-01 84.5% 95.4%
4nq0A00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.52 46.0 3.97e-01 95.7% 75.2%
3iq1B00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.52 41.0 4.21e-01 85.1% 85.5%
6xpdA01 1.20.1510.10 Mainly Alpha › Up-down Bundle › Alpha-lytic protease prodomain-like › Cation efflux protein transmembrane domain 0.51 46.0 4.26e-01 95.7% 96.0%
2rkkA01 1.25.40.270 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Vacuolar protein sorting-associated protein vta1 0.50 39.0 4.01e-01 82.6% 97.4%
ECOD (37)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3499296 133.1.1.1 ↗ alpha bundles › DH domain-like › DBL homology domain (DH-domain) › DBL homology domain (DH-domain) › RhoGEF 0.76 55.0 5.47e-01 75.2% 99.4%
4987854 109.3.1.487 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › DUF5667 0.75 60.0 6.46e-01 83.2% 95.7%
3027840 109.3.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.75 59.0 5.84e-01 82.0% 83.4%
3238399 109.4.1.1 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › 14-3-3 0.71 52.0 5.92e-01 75.2% 100.0%
3615330 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.71 61.0 4.42e-01 90.1% 46.5%
3269345 5000.4.1.1 ↗ alpha arrays › Toxins' membrane translocation domains › delta-Endotoxin (insectocide), N-terminal domain › delta-Endotoxin (insectocide), N-terminal domain › Endotoxin_N 0.68 60.0 5.23e-01 96.9% 89.4%
4825023 109.3.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.68 49.0 4.57e-01 82.6% 59.7%
3218207 174.1.1.0 ↗ few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.68 50.0 5.23e-01 100.0% 84.1%
3611298 174.1.1.0 ↗ few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.65 48.0 5.21e-01 99.4% 91.7%
3412554 174.1.1.1 ↗ few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin 0.65 43.0 4.80e-01 100.0% 86.4%
5061284 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.64 46.0 4.07e-01 80.1% 51.7%
3406232 174.1.1.1 ↗ few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin 0.64 46.0 4.92e-01 100.0% 86.3%
3231048 174.1.1.1 ↗ few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin 0.63 45.0 4.84e-01 100.0% 85.7%
3939933 601.1.2.4 ↗ alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Talin_R4 0.61 50.0 5.28e-01 99.4% 94.5%
3494783 174.1.1.1 ↗ few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin 0.61 42.0 4.51e-01 100.0% 82.1%
3217364 174.1.1.0 ↗ few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.60 47.0 4.84e-01 99.4% 87.3%
3511227 601.15.1.2 ↗ alpha bundles › Four-helical up-and-down bundle › Proteasome activator reg(alpha) › Proteasome activator reg(alpha) › PA28_C 0.60 39.0 3.66e-01 79.5% 55.8%
4412723 109.4.1.170 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › CLASP_N 0.59 56.0 3.42e-01 100.0% 25.0%
3703485 4177.1.1.34 ↗ alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › Flagellar_rod 0.59 44.0 3.53e-01 77.6% 72.2%
3254569 174.1.1.0 ↗ few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.58 46.0 4.76e-01 100.0% 87.3%
4986068 5082.1.1.1 ↗ alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux 0.58 41.0 3.87e-01 72.7% 100.0%
3638102 1174.1.1.2 ↗ alpha complex topology › Potassium channel TMEM175 › Potassium channel TMEM175 › Potassium channel TMEM175 › LtrA 0.57 44.0 4.27e-01 81.4% 83.2%
3908662 109.4.1.1 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › 14-3-3 0.57 50.0 4.40e-01 95.7% 90.4%
3784860 109.4.1.1471 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_IPO5 0.57 50.0 4.18e-01 94.4% 66.2%
3989350 5082.1.1.1 ↗ alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux 0.57 45.0 4.15e-01 83.2% 79.5%
3470897 174.1.1.0 ↗ few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.57 51.0 5.07e-01 99.4% 93.9%
3936980 174.1.1.1 ↗ few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin 0.56 49.0 4.91e-01 99.4% 90.9%
3723424 1174.1.1.2 ↗ alpha complex topology › Potassium channel TMEM175 › Potassium channel TMEM175 › Potassium channel TMEM175 › LtrA 0.55 45.0 4.14e-01 85.7% 73.2%
2320846 150.1.1.0 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.55 52.0 4.86e-01 100.0% 98.5%
3611462 174.1.1.0 ↗ few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.55 42.0 4.56e-01 100.0% 92.1%
3367959 109.62.1.3 ↗ alpha superhelices › Repetitive alpha hairpins › AFF4 C-terminal homology domain › AFF4 C-terminal homology domain › THD_CWZF3-5-7 0.55 47.0 4.20e-01 91.9% 87.6%
3798366 192.29.1.0 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.53 38.0 3.37e-01 78.9% 52.4%
3460083 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.53 45.0 3.92e-01 95.0% 58.4%
3785302 109.5.1.1 ↗ alpha superhelices › Repetitive alpha hairpins › adenylylcyclase associated protein, CAP-N › adenylylcyclase associated protein, CAP-N › CAP_N 0.53 46.0 4.47e-01 97.5% 87.0%
5076444 604.5.1.1 ↗ alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div 0.52 48.0 4.41e-01 99.4% 97.1%
5064257 5082.1.1.1 ↗ alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux 0.52 41.0 3.79e-01 82.6% 79.0%
3682819 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.51 45.0 3.72e-01 98.8% 58.4%