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SRR1747046_scaffold_4_prodigal-single.1__X__X__00079
Bact-VirSRR1747046_scaffold_4_prodigal-single.1__X__X__00079
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 4-139
Domain cluster:
rep: ON464759.1__UTV60802.1__JDFnp1_14__00014__D510-656
CATH (8)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2gsvA00 | 6.10.140.40 | Special › Helix non-globular › Helix Hairpins › | 0.57 | 29.0 | 4.00e-01 | 87.5% | 100.0% |
| 4exjA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.56 | 32.0 | 3.40e-01 | 91.9% | 61.2% |
| 4gltA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.55 | 32.0 | 3.45e-01 | 89.0% | 65.8% |
| 3hyuA00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.55 | 32.0 | 3.23e-01 | 94.9% | 55.3% |
| 2pvqA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.54 | 33.0 | 3.74e-01 | 100.0% | 79.2% |
| 2x64A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.51 | 31.0 | 3.32e-01 | 89.7% | 68.1% |
| 2zhgA00 | 1.10.1660.10 | Mainly Alpha › Orthogonal Bundle › Multidrug-efflux Transporter Regulator; Chain: A; Domain 2 › | 0.51 | 35.0 | 3.71e-01 | 87.5% | 78.5% |
| 1ldjA02 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.50 | 37.0 | 3.88e-01 | 97.8% | 85.4% |
D2
high
residues 147-264
Domain cluster:
rep: MG592415.1__AUR83112.1__NVP1031O_130__00130__D624-731
CATH (26)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3h0gA05 | 1.10.132.30 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › RNA polymerase Rpb1 funnel domain | 0.79 | 65.0 | 6.01e-01 | 86.4% | 98.6% |
| 2o5iN07 | 1.10.132.30 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › RNA polymerase Rpb1 funnel domain | 0.77 | 62.0 | 6.27e-01 | 84.7% | 99.1% |
| 3h36A00 | 1.10.10.400 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Polyribonucleotide nucleotidyltransferase, RNA-binding domain | 0.68 | 44.0 | 5.25e-01 | 88.1% | 98.7% |
| 2yb5F01 | 1.20.1280.250 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.62 | 40.0 | 4.57e-01 | 84.7% | 89.5% |
| 4adnA01 | 1.20.1280.250 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.62 | 41.0 | 4.64e-01 | 83.9% | 91.8% |
| 3agtA00 | 1.20.120.50 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like | 0.60 | 46.0 | 4.44e-01 | 80.5% | 81.2% |
| 4jz8B00 | 3.40.1160.10 | Alpha Beta › 3-Layer(aba) Sandwich › Carbamate kinase › Acetylglutamate kinase-like | 0.58 | 47.0 | 3.50e-01 | 88.1% | 86.5% |
| 4xpwA00 | 1.20.120.50 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like | 0.57 | 44.0 | 4.24e-01 | 80.5% | 79.4% |
| 1y4cA03 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.57 | 42.0 | 4.35e-01 | 78.0% | 82.3% |
| 4j8dD00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.56 | 39.0 | 3.55e-01 | 89.8% | 51.9% |
| 2ap3A00 | 1.20.120.570 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YkyA-like | 0.56 | 43.0 | 3.66e-01 | 79.7% | 72.4% |
| 2wbpA00 | 3.60.130.10 | Alpha Beta › 4-Layer Sandwich › Double-stranded beta-helix › Clavaminate synthase-like | 0.56 | 47.0 | 3.45e-01 | 93.2% | 92.8% |
| 6a7hA01 | 1.20.140.180 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › | 0.55 | 33.0 | 3.20e-01 | 70.3% | 51.5% |
| 1nklA00 | 1.10.225.10 | Mainly Alpha › Orthogonal Bundle › NK-Lysin › Saposin-like | 0.55 | 34.0 | 3.97e-01 | 85.6% | 93.6% |
| 3l8rA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.55 | 37.0 | 3.99e-01 | 70.3% | 92.2% |
| 1zb1A00 | 1.25.40.280 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › alix/aip1 like domains | 0.54 | 46.0 | 3.28e-01 | 94.1% | 83.9% |
| 2jx0A00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.53 | 42.0 | 4.10e-01 | 84.7% | 85.5% |
| 4iggB02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.53 | 40.0 | 4.02e-01 | 79.7% | 89.3% |
| 4i9cA02 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.52 | 40.0 | 3.30e-01 | 89.8% | 43.9% |
| 4htpB00 | 1.10.3260.10 | Mainly Alpha › Orthogonal Bundle › DNA ligase i, domain 1 › DNA ligase, ATP-dependent, N-terminal domain | 0.52 | 47.0 | 3.81e-01 | 99.2% | 91.0% |
| 3jz0A02 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.52 | 42.0 | 4.07e-01 | 88.1% | 95.4% |
| 3iqcA00 | 1.20.120.340 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS | 0.51 | 40.0 | 4.02e-01 | 83.1% | 89.1% |
| 6z74C02 | 1.20.120.530 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like | 0.51 | 44.0 | 4.09e-01 | 99.2% | 87.4% |
| 3nivC02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.51 | 41.0 | 4.06e-01 | 85.6% | 96.0% |
| 5tpmB00 | 1.20.120.530 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like | 0.51 | 45.0 | 4.27e-01 | 99.2% | 88.7% |
| 2irmA00 | 3.60.40.10 | Alpha Beta › 4-Layer Sandwich › Phosphatase 2c; domain 1 › PPM-type phosphatase domain | 0.51 | 45.0 | 3.28e-01 | 99.2% | 39.5% |
ECOD (23)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4887358 | 4958.1.1.4 ↗ | a+b complex topology › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_5 | 0.80 | 74.0 | 6.65e-01 | 100.0% | 82.6% |
| 4642508 | 4958.1.1.1 ↗ | a+b complex topology › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_5,RNA_pol_Rpb1_4 | 0.80 | 74.0 | 5.66e-01 | 100.0% | 52.2% |
| 4513601 | 4246.1.1.0 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit | 0.79 | 73.0 | 4.68e-01 | 100.0% | 24.9% |
| 4887310 | 4958.1.1.2 ↗ | a+b complex topology › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_4 | 0.72 | 65.0 | 5.45e-01 | 100.0% | 75.9% |
| 4498171 | 101.11.1.1 ↗ | alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase | 0.72 | 43.0 | 5.25e-01 | 87.3% | 93.3% |
| 4109823 | 4967.1.1.6 ↗ | alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › Intron_maturas2 | 0.69 | 41.0 | 4.37e-01 | 84.7% | 65.7% |
| 4092432 | 101.11.1.1 ↗ | alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase | 0.68 | 44.0 | 4.87e-01 | 85.6% | 81.1% |
| 171404 | 101.11.1.0 ↗ | alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 | 0.68 | 44.0 | 5.25e-01 | 88.1% | 98.7% |
| 4287075 | 101.11.1.1 ↗ | alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase | 0.66 | 41.0 | 4.56e-01 | 88.1% | 80.0% |
| 3226700 | 4953.1.1.20 ↗ | beta barrels › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › Yip1 | 0.66 | 46.0 | 4.33e-01 | 78.0% | 58.6% |
| 3211136 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.62 | 36.0 | 4.51e-01 | 83.9% | 95.7% |
| 4612393 | 7579.1.1.234 ↗ | a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › DUF6792 | 0.59 | 52.0 | 3.93e-01 | 94.1% | 53.7% |
| 3591396 | 3866.1.1.0 ↗ | extended segments › Mitochondrial 54S ribosomal protein L25 › Mitochondrial 54S ribosomal protein L25 › Mitochondrial 54S ribosomal protein L25 | 0.58 | 42.0 | 4.61e-01 | 75.4% | 95.8% |
| 5009310 | 601.7.1.3 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › PaREP1 | 0.58 | 43.0 | 4.28e-01 | 77.1% | 95.8% |
| 4943658 | 1075.1.2.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain | 0.55 | 41.0 | 3.56e-01 | 78.8% | 76.2% |
| 3612915 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.53 | 37.0 | 3.90e-01 | 70.3% | 95.2% |
| 3554259 | 4095.1.1.1 ↗ | alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_N | 0.52 | 48.0 | 3.81e-01 | 100.0% | 92.2% |
| 3969366 | 628.1.1.1 ↗ | alpha bundles › Fatty acid responsive transcription factor FadR, C-terminal domain › Fatty acid responsive transcription factor FadR, C-terminal domain › Fatty acid responsive transcription factor FadR, C-terminal domain › FCD | 0.51 | 44.0 | 4.15e-01 | 94.9% | 83.4% |
| 5044572 | 310.2.1.0 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF | 0.51 | 40.0 | 4.21e-01 | 89.8% | 93.3% |
| 3985185 | 3226.1.1.1 ↗ | alpha complex topology › Uracil Transporter UraA › Uracil Transporter UraA › Uracil Transporter UraA › Xan_ur_permease | 0.51 | 45.0 | 3.12e-01 | 98.3% | 62.4% |
| 3281023 | 628.1.1.1 ↗ | alpha bundles › Fatty acid responsive transcription factor FadR, C-terminal domain › Fatty acid responsive transcription factor FadR, C-terminal domain › Fatty acid responsive transcription factor FadR, C-terminal domain › FCD | 0.51 | 45.0 | 4.22e-01 | 100.0% | 86.7% |
| 3804987 | 5001.1.1.122 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › PF27754 | 0.51 | 39.0 | 2.95e-01 | 83.1% | 62.8% |
| 3465357 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.51 | 37.0 | 3.81e-01 | 76.3% | 89.6% |
D3
medium
residues 265-290_371-395
Domain cluster:
representative
CATH (52)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2f93B00 | 1.10.287.470 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.78 | 66.0 | 6.69e-01 | 96.1% | 98.0% |
| 4okvE00 | 6.10.140.1890 | Special › Helix non-globular › Helix Hairpins › | 0.78 | 68.0 | 6.30e-01 | 100.0% | 83.1% |
| 2j5iA02 | 6.10.250.2850 | Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.74 | 51.0 | 5.49e-01 | 82.4% | 100.0% |
| 6xxvC00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.73 | 62.0 | 4.89e-01 | 98.0% | 55.9% |
| 3besR03 | 6.10.140.1480 | Special › Helix non-globular › Helix Hairpins › | 0.71 | 56.0 | 5.48e-01 | 98.0% | 82.1% |
| 4jylA02 | 1.10.12.10 | Mainly Alpha › Orthogonal Bundle › Lyase 2-enoyl-coa Hydratase; Chain A, domain 2 › Lyase 2-enoyl-coa Hydratase, Chain A, domain 2 | 0.71 | 49.0 | 5.03e-01 | 74.5% | 83.7% |
| 4w4kA00 | 1.10.287.850 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain | 0.70 | 58.0 | 5.09e-01 | 98.0% | 95.1% |
| 3x0uB01 | 1.20.190.10 | Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain | 0.70 | 59.0 | 3.81e-01 | 98.0% | 23.0% |
| 1lrzA03 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.69 | 55.0 | 5.26e-01 | 92.2% | 100.0% |
| 2kwhA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.69 | 54.0 | 5.31e-01 | 88.2% | 96.4% |
| 3vm9A02 | 6.10.140.2110 | Special › Helix non-globular › Helix Hairpins › | 0.69 | 58.0 | 5.66e-01 | 98.0% | 94.7% |
| 7zxkC01 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.69 | 56.0 | 4.04e-01 | 92.2% | 100.0% |
| 2yksA02 | 1.20.58.390 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Neurotransmitter-gated ion-channel transmembrane domain | 0.69 | 60.0 | 4.60e-01 | 100.0% | 57.3% |
| 2bvlA01 | 1.20.58.1190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.67 | 52.0 | 4.53e-01 | 90.2% | 54.7% |
| 1u89A00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.67 | 54.0 | 4.11e-01 | 98.0% | 37.4% |
| 5u4nA00 | 3.20.20.70 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I | 0.67 | 54.0 | 3.31e-01 | 94.1% | 87.1% |
| 3u5nA02 | 1.20.920.10 | Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like | 0.67 | 51.0 | 3.99e-01 | 88.2% | 55.0% |
| 3fxdB00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.66 | 55.0 | 5.31e-01 | 96.1% | 86.2% |
| 4hzuS00 | 1.10.1760.20 | Mainly Alpha › Orthogonal Bundle › Arp2/3 complex 21 kDa subunit ARPC3 › | 0.66 | 56.0 | 4.03e-01 | 100.0% | 38.4% |
| 2au3A04 | 1.20.50.30 | Mainly Alpha › Up-down Bundle › Pheromone ER-1 › | 0.66 | 43.0 | 4.22e-01 | 88.2% | 61.8% |
| 3fseB02 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.66 | 53.0 | 3.97e-01 | 96.1% | 72.2% |
| 1ni3A03 | 1.10.150.300 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Obg-related GTPase Ych/YyaF, coiled-coil domain | 0.65 | 54.0 | 4.57e-01 | 96.1% | 60.4% |
| 1dt9A01 | 3.30.960.10 | Alpha Beta › 2-Layer Sandwich › Translation, Eukaryotic Peptide Chain Release Factor Subunit 1; Chain A › eRF1 domain 1 | 0.65 | 55.0 | 4.44e-01 | 100.0% | 67.6% |
| 1gvfB00 | 3.20.20.70 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I | 0.65 | 51.0 | 3.32e-01 | 94.1% | 91.6% |
| 1nafA02 | 1.20.58.160 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.64 | 51.0 | 4.38e-01 | 96.1% | 54.1% |
| 1ydxA02 | 1.10.287.1120 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein | 0.63 | 53.0 | 4.43e-01 | 94.1% | 58.9% |
| 2z0qA01 | 1.20.900.10 | Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain | 0.63 | 52.0 | 3.55e-01 | 94.1% | 25.4% |
| 1sg2A00 | 3.30.910.20 | Alpha Beta › 2-Layer Sandwich › Protein Binding, DinI Protein; Chain A › Skp domain | 0.63 | 52.0 | 3.92e-01 | 98.0% | 55.3% |
| 2ktmA00 | 1.10.790.10 | Mainly Alpha › Orthogonal Bundle › Major Prion Protein › Prion/Doppel protein, beta-ribbon domain | 0.63 | 51.0 | 4.72e-01 | 94.1% | 91.2% |
| 4h63K00 | 1.10.287.3490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.63 | 53.0 | 4.36e-01 | 98.0% | 53.1% |
| 1zpyA00 | 6.10.140.1960 | Special › Helix non-globular › Helix Hairpins › | 0.62 | 51.0 | 4.29e-01 | 96.1% | 52.7% |
| 4gouA03 | 1.20.900.10 | Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain | 0.62 | 48.0 | 3.38e-01 | 94.1% | 82.2% |
| 2e5yA02 | 1.20.5.440 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › ATP synthase delta/epsilon subunit, C-terminal domain | 0.62 | 48.0 | 5.06e-01 | 96.1% | 97.8% |
| 1exzB00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.61 | 50.0 | 3.81e-01 | 98.0% | 61.4% |
| 4e6nA02 | 6.10.140.1010 | Special › Helix non-globular › Helix Hairpins › | 0.61 | 51.0 | 4.70e-01 | 94.1% | 74.2% |
| 2wdqC00 | 1.20.1300.10 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit | 0.61 | 50.0 | 3.91e-01 | 96.1% | 41.3% |
| 1zxjA01 | 1.10.3120.10 | Mainly Alpha › Orthogonal Bundle › Trigger factor, domain 2 › Trigger factor, C-terminal domain | 0.61 | 50.0 | 3.42e-01 | 92.2% | 65.4% |
| 3icxA01 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.61 | 49.0 | 4.50e-01 | 98.0% | 93.3% |
| 3d36B02 | 1.10.287.130 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain | 0.61 | 48.0 | 4.63e-01 | 96.1% | 77.0% |
| 2xzmO02 | 1.10.287.10 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › S15/NS1, RNA-binding | 0.61 | 50.0 | 4.51e-01 | 92.2% | 70.0% |
| 2mpkA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.61 | 48.0 | 4.47e-01 | 98.0% | 82.4% |
| 4fvmA06 | 1.10.287.690 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › B family DNA polymerase, finger domain | 0.60 | 46.0 | 4.67e-01 | 86.3% | 95.8% |
| 4akgA02 | 1.20.140.100 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Dynein motor heavy chain, linker domain, N-terminal subdomain | 0.60 | 51.0 | 3.61e-01 | 100.0% | 44.6% |
| 2rbdA01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.59 | 48.0 | 3.62e-01 | 100.0% | 71.3% |
| 3m6jA01 | 1.20.1260.40 | Mainly Alpha › Up-down Bundle › Ferritin › | 0.59 | 52.0 | 4.02e-01 | 100.0% | 43.6% |
| 3mq1A01 | 1.20.58.970 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.59 | 48.0 | 4.10e-01 | 98.0% | 69.6% |
| 2lw1A00 | 1.10.287.380 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Valyl-tRNA synthetase, C-terminal domain | 0.58 | 49.0 | 4.22e-01 | 98.0% | 61.2% |
| 3wfwA00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.57 | 47.0 | 3.61e-01 | 100.0% | 89.1% |
| 1qguB04 | 1.20.89.10 | Mainly Alpha › Up-down Bundle › Nitrogenase Molybdenum-iron Protein, subunit B; domain 4 › Nitrogenase Molybdenum-iron Protein, subunit B, domain 4 | 0.54 | 41.0 | 3.64e-01 | 90.2% | 66.3% |
| 2pusA05 | 1.10.1740.80 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › | 0.53 | 39.0 | 3.45e-01 | 86.3% | 52.5% |
| 1m3sB00 | 3.40.50.10490 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 | 0.53 | 46.0 | 3.15e-01 | 98.0% | 76.5% |
| 3l4aA00 | 1.10.238.20 | Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › Pheromone/general odorant binding protein domain | 0.51 | 39.0 | 3.17e-01 | 92.2% | 42.1% |
ECOD (44)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4831662 | 5043.1.1.1 ↗ | extended segments › Sensor proteins transmembrane domains › Htr2 transmembrane domain-like › Htr2 transmembrane domain-like › Htr2 | 0.76 | 65.0 | 6.03e-01 | 98.0% | 80.3% |
| 3236471 | 5054.1.1.8 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 | 0.76 | 65.0 | 4.04e-01 | 98.0% | 32.9% |
| 4942626 | 5058.1.1.16 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 | 0.75 | 63.0 | 5.11e-01 | 96.1% | 54.0% |
| 4323124 | 109.3.1.2 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank,Ank_2 | 0.75 | 61.0 | 3.76e-01 | 94.1% | 15.8% |
| 4449117 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.72 | 59.0 | 5.23e-01 | 96.1% | 67.5% |
| 4883924 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.72 | 61.0 | 5.28e-01 | 96.1% | 66.3% |
| 3989094 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.71 | 56.0 | 5.13e-01 | 96.1% | 65.7% |
| 197868 | 614.1.1.0 ↗ | alpha duplicates or obligate multimers › L27 domain › L27 domain › L27 domain | 0.71 | 56.0 | 5.63e-01 | 98.0% | 90.2% |
| 3497936 | 601.7.1.36 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › UFL1 | 0.71 | 61.0 | 4.55e-01 | 100.0% | 46.7% |
| 3563871 | 603.1.1.121 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF30821 | 0.69 | 58.0 | 4.56e-01 | 98.0% | 55.7% |
| 3387239 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.69 | 57.0 | 4.42e-01 | 98.0% | 40.8% |
| 5070059 | 3834.1.1.25 ↗ | alpha bundles › TcA alpha pore-forming domain › TcA alpha pore-forming domain › TcA alpha pore-forming domain › DUF7121 | 0.68 | 56.0 | 3.62e-01 | 96.1% | 97.6% |
| 4550256 | 604.12.1.76 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › IspA | 0.68 | 55.0 | 4.94e-01 | 94.1% | 65.3% |
| 3756535 | 604.1.1.5 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin_3 | 0.68 | 56.0 | 4.44e-01 | 98.0% | 51.3% |
| 3957419 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.67 | 56.0 | 5.01e-01 | 98.0% | 76.0% |
| 4172979 | 101.11.1.1 ↗ | alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase | 0.67 | 54.0 | 4.42e-01 | 92.2% | 63.0% |
| 3888978 | 3812.1.1.0 ↗ | alpha bundles › Type III secretion protein YscE › Type III secretion protein YscE › Type III secretion protein YscE | 0.67 | 56.0 | 4.37e-01 | 100.0% | 45.0% |
| 3414399 | 5086.1.1.106 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › DUF725 | 0.66 | 53.0 | 3.85e-01 | 98.0% | 56.5% |
| 3704 | 601.1.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin | 0.66 | 54.0 | 4.89e-01 | 94.1% | 69.4% |
| 3539986 | 5058.1.1.90 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › TMEM169 | 0.66 | 58.0 | 5.12e-01 | 100.0% | 77.3% |
| 1948638 | 4970.1.1.1 ↗ | alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B | 0.66 | 55.0 | 5.51e-01 | 100.0% | 98.1% |
| 3402853 | 192.6.1.0 ↗ | alpha bundles › Long alpha-hairpin › Epsilon subunit of F1F0-ATP synthase C-terminal domain › Epsilon subunit of F1F0-ATP synthase C-terminal domain | 0.66 | 52.0 | 5.32e-01 | 94.1% | 98.0% |
| 4597007 | 192.6.1.0 ↗ | alpha bundles › Long alpha-hairpin › Epsilon subunit of F1F0-ATP synthase C-terminal domain › Epsilon subunit of F1F0-ATP synthase C-terminal domain | 0.66 | 49.0 | 5.19e-01 | 82.4% | 97.8% |
| 3958387 | 1075.5.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter | 0.65 | 57.0 | 3.99e-01 | 100.0% | 60.6% |
| 3597348 | 207.1.1.0 ↗ | beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats | 0.65 | 53.0 | 3.35e-01 | 98.0% | 18.4% |
| 3969538 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.65 | 53.0 | 5.19e-01 | 94.1% | 96.4% |
| 3983659 | 4970.1.1.0 ↗ | alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I | 0.65 | 45.0 | 4.18e-01 | 78.4% | 56.9% |
| 3892500 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.65 | 53.0 | 4.28e-01 | 98.0% | 46.4% |
| 2720300 | 192.22.1.1 ↗ | alpha bundles › Long alpha-hairpin › Ral binding domain of RLIP76 › Ral binding domain of RLIP76 › RLIP76_Ral-bd | 0.65 | 53.0 | 5.39e-01 | 94.1% | 96.1% |
| 3461932 | 3922.1.1.189 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › DUF630 | 0.64 | 51.0 | 4.28e-01 | 94.1% | 87.4% |
| 3878682 | 11.12.1.1 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Nicotinic receptor ligand binding domain-like › Nicotinic receptor ligand binding domain-like › Neur_chan_LBD | 0.63 | 49.0 | 3.37e-01 | 90.2% | 23.8% |
| 3731364 | 3922.1.1.137 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › HisKA | 0.62 | 52.0 | 4.89e-01 | 98.0% | 84.6% |
| 4994917 | 3834.1.1.25 ↗ | alpha bundles › TcA alpha pore-forming domain › TcA alpha pore-forming domain › TcA alpha pore-forming domain › DUF7121 | 0.62 | 51.0 | 3.36e-01 | 98.0% | 90.6% |
| 3186617 | 2004.1.1.30 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C | 0.62 | 51.0 | 3.21e-01 | 100.0% | 30.7% |
| 4565383 | 192.6.1.0 ↗ | alpha bundles › Long alpha-hairpin › Epsilon subunit of F1F0-ATP synthase C-terminal domain › Epsilon subunit of F1F0-ATP synthase C-terminal domain | 0.61 | 48.0 | 4.89e-01 | 88.2% | 92.0% |
| 4544002 | 192.6.1.1 ↗ | alpha bundles › Long alpha-hairpin › Epsilon subunit of F1F0-ATP synthase C-terminal domain › Epsilon subunit of F1F0-ATP synthase C-terminal domain › ATP-synt_DE | 0.61 | 50.0 | 5.08e-01 | 92.2% | 100.0% |
| 5072044 | 213.1.1.17 ↗ | a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) › DUF1122 | 0.61 | 45.0 | 2.98e-01 | 80.4% | 21.8% |
| 5000698 | 604.38.1.0 ↗ | alpha bundles › Spectrin repeat-like › Legionella effector SdeA 3-helical bundle › Legionella effector SdeA 3-helical bundle | 0.61 | 49.0 | 3.96e-01 | 92.2% | 47.6% |
| 4396464 | 605.1.1.305 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › Exonuc_VII_S | 0.60 | 51.0 | 4.86e-01 | 96.1% | 88.3% |
| 4646268 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.60 | 49.0 | 4.52e-01 | 98.0% | 70.0% |
| 3234298 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.59 | 49.0 | 4.82e-01 | 96.1% | 92.7% |
| 3743879 | 604.6.1.0 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain | 0.58 | 48.0 | 4.00e-01 | 98.0% | 51.6% |
| 3175888 | 6155.1.1.4 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › MPC | 0.57 | 48.0 | 3.82e-01 | 98.0% | 48.2% |
| 4616546 | 6155.1.1.4 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › MPC | 0.53 | 41.0 | 3.46e-01 | 96.1% | 48.6% |
D4
medium
residues 291-370_561-597
Domain cluster:
representative
D5
medium
residues 396-560
Domain cluster:
representative
CATH (1)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1g3pA02 | 3.90.450.1 | Alpha Beta › Alpha-Beta Complex › Minor Coat Protein; domain 2 › Minor Coat Protein; Domain 2 | 0.56 | 30.0 | 3.66e-01 | 86.1% | 80.8% |
ECOD (4)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4036893 | 325.1.7.0 ↗ | a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif | 0.66 | 34.0 | 4.61e-01 | 70.3% | 98.8% |
| 4367226 | 325.1.7.0 ↗ | a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif | 0.66 | 34.0 | 4.50e-01 | 70.9% | 94.1% |
| 4209177 | 325.1.7.0 ↗ | a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif | 0.58 | 34.0 | 4.31e-01 | 71.5% | 98.9% |
| 4134639 | 325.1.7.0 ↗ | a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif | 0.57 | 34.0 | 4.28e-01 | 71.5% | 99.0% |
D6
medium
residues 600-644