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SRR1747046_scaffold_4_prodigal-single.1__X__X__00114

Bact-Vir

SRR1747046_scaffold_4_prodigal-single.1__X__X__00114

Identity

Kingdom:
phage

Quality

86.2 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 507-603
PDB
Domain cluster: representative
CATH (5)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3qexA06 3.40.1820.10 Alpha Beta › 3-Layer(aba) Sandwich › Ribonuclease H-like motif › DnaQ-like 3'-5' exonuclease 0.71 60.0 6.18e-01 100.0% 94.6%
4fxdA06 1.10.132.60 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › B family DNA polymerase, thumb domain 0.70 48.0 4.03e-01 100.0% 42.5%
4b08A08 3.40.1820.20 Alpha Beta › 3-Layer(aba) Sandwich › Ribonuclease H-like motif › B family DNA polymerase, thumb domain, alpha/beta motif 0.68 47.0 5.14e-01 100.0% 87.5%
2gv9B06 1.10.132.60 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › B family DNA polymerase, thumb domain 0.67 56.0 4.35e-01 100.0% 42.9%
1tgoA05 1.10.132.60 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › B family DNA polymerase, thumb domain 0.65 43.0 3.63e-01 100.0% 39.5%
ECOD (7)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4978606 4969.1.1.0 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I 0.75 52.0 4.43e-01 100.0% 45.2%
4956225 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.75 50.0 4.29e-01 100.0% 45.5%
5025210 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.74 51.0 4.42e-01 100.0% 46.0%
4025114 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.66 51.0 4.24e-01 100.0% 47.1%
3484038 4969.1.1.0 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I 0.57 46.0 3.60e-01 100.0% 41.0%
223884 3610.1.1.2 a+b complex topology › Tetrahydrodipicolinate N-succinyletransferase N-terminal domain › Tetrahydrodipicolinate N-succinyletransferase N-terminal domain › Tetrahydrodipicolinate N-succinyletransferase N-terminal domain › THDPS_M,THDPS_N 0.52 36.0 3.04e-01 72.2% 50.0%
4247236 2004.1.1.433 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_23 0.51 38.0 2.61e-01 79.4% 82.4%
D2 medium residues 5-83
PDB
Domain cluster: representative
CATH (26)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1gt0D00 1.10.30.10 Mainly Alpha › Orthogonal Bundle › DNA Binding (I), subunit A › High mobility group box domain 0.75 50.0 5.08e-01 87.3% 69.6%
2co9A00 1.10.30.10 Mainly Alpha › Orthogonal Bundle › DNA Binding (I), subunit A › High mobility group box domain 0.74 50.0 4.59e-01 87.3% 53.9%
2e6oA00 1.10.30.10 Mainly Alpha › Orthogonal Bundle › DNA Binding (I), subunit A › High mobility group box domain 0.70 47.0 4.61e-01 87.3% 63.2%
1wgfA01 1.10.30.10 Mainly Alpha › Orthogonal Bundle › DNA Binding (I), subunit A › High mobility group box domain 0.67 44.0 5.04e-01 84.8% 100.0%
6abqB00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.66 36.0 3.26e-01 79.7% 39.6%
4hqeA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.62 31.0 2.86e-01 75.9% 36.2%
6j09A04 3.10.20.310 Alpha Beta › Roll › Ubiquitin-like (UB roll) › membrane protein fhac 0.62 32.0 3.29e-01 74.7% 49.4%
4jylA02 1.10.12.10 Mainly Alpha › Orthogonal Bundle › Lyase 2-enoyl-coa Hydratase; Chain A, domain 2 › Lyase 2-enoyl-coa Hydratase, Chain A, domain 2 0.62 32.0 3.89e-01 75.9% 79.6%
4k3cA01 3.10.20.310 Alpha Beta › Roll › Ubiquitin-like (UB roll) › membrane protein fhac 0.62 31.0 3.08e-01 73.4% 45.1%
3elkA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.61 34.0 3.13e-01 81.0% 41.9%
3l7wA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.60 34.0 3.13e-01 82.3% 41.0%
1bm9A00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.58 35.0 3.11e-01 86.1% 39.2%
1dp7P00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.58 36.0 3.65e-01 87.3% 63.2%
2qbyB03 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.54 34.0 3.31e-01 82.3% 54.9%
2dqlA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.54 34.0 3.02e-01 82.3% 43.5%
4mtnA01 3.30.1480.10 Alpha Beta › 2-Layer Sandwich › N Utilization Substance Protein A; Chain:P; domain 4 › NusA, N-terminal domain 0.54 39.0 3.67e-01 75.9% 73.7%
6s2wA01 3.30.2260.10 Alpha Beta › 2-Layer Sandwich › ERH-like fold › Enhancer of rudimentary 0.54 30.0 3.00e-01 74.7% 51.2%
5dymA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.54 32.0 3.03e-01 82.3% 45.8%
3hnoA01 3.40.50.450 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.53 36.0 2.59e-01 88.6% 24.9%
5h20A00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.53 31.0 2.87e-01 81.0% 42.7%
2wcyA01 3.30.60.30 Alpha Beta › 2-Layer Sandwich › Wheat Germ Agglutinin (Isolectin 2); domain 1 › 0.52 35.0 3.59e-01 98.7% 72.0%
1fi8C00 2.60.40.550 Mainly Beta › Sandwich › Immunoglobulin-like › Ecotin 0.52 27.0 2.75e-01 74.7% 43.6%
2nmlA00 3.30.2260.10 Alpha Beta › 2-Layer Sandwich › ERH-like fold › Enhancer of rudimentary 0.52 36.0 3.37e-01 75.9% 58.0%
4esbA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.51 31.0 2.91e-01 82.3% 44.7%
3cuqA02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.51 31.0 3.10e-01 79.7% 58.0%
1oi2A02 3.30.1180.20 Alpha Beta › 2-Layer Sandwich › Hypothetical Protein Tm841; Chain: A;domain 3 › Dihydroxyacetone kinase; domain 2 0.50 35.0 2.88e-01 73.4% 45.7%
ECOD (34)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4942265 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.68 41.0 4.04e-01 82.3% 56.5%
3421312 263.1.1.1 a+b three layers › SRF-like › SRF-like › SRF-like › SRF-TF 0.64 27.0 2.89e-01 72.2% 42.9%
5051542 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.63 55.0 4.25e-01 100.0% 58.9%
3438721 5081.1.1.1 alpha bundles › Rhomboid-like › Rhomboid-like › Rhomboid-like › Rhomboid 0.62 44.0 3.28e-01 74.7% 59.0%
3257174 101.1.2.148 alpha arrays › HTH › HTH › winged helix domain › ORC5_C 0.61 36.0 3.06e-01 81.0% 34.6%
169108 101.1.2.48 alpha arrays › HTH › HTH › winged helix domain › PadR 0.61 34.0 3.13e-01 81.0% 41.9%
3988732 101.1.2.48 alpha arrays › HTH › HTH › winged helix domain › PadR 0.60 34.0 3.08e-01 86.1% 39.8%
3355197 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.59 35.0 3.25e-01 83.5% 45.0%
5041315 101.1.2.48 alpha arrays › HTH › HTH › winged helix domain › PadR 0.57 34.0 3.17e-01 81.0% 46.0%
3934845 5001.1.1.66 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Srg 0.55 47.0 3.31e-01 100.0% 57.1%
5043001 101.1.2.135 alpha arrays › HTH › HTH › winged helix domain › MarR_2 0.53 30.0 2.81e-01 81.0% 41.0%
3627712 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.53 46.0 2.80e-01 100.0% 31.6%
3931457 5001.1.1.44 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srv 0.53 45.0 3.17e-01 100.0% 54.2%
3224339 5001.1.1.66 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Srg 0.53 46.0 3.18e-01 100.0% 51.3%
3667109 101.1.2.111 alpha arrays › HTH › HTH › winged helix domain › RQC 0.53 41.0 3.50e-01 82.3% 52.0%
3933306 5001.1.1.44 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srv 0.53 45.0 3.32e-01 100.0% 64.6%
3928178 5001.1.1.44 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srv 0.53 44.0 3.10e-01 100.0% 54.0%
3930248 5001.1.1.44 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srv 0.52 44.0 3.08e-01 100.0% 65.2%
5031662 101.1.2.48 alpha arrays › HTH › HTH › winged helix domain › PadR 0.52 31.0 2.72e-01 81.0% 36.0%
3928383 5001.1.1.44 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srv 0.52 45.0 3.33e-01 100.0% 65.8%
3925962 5001.1.1.44 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srv 0.52 44.0 3.07e-01 100.0% 68.0%
3934910 5001.1.1.44 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srv 0.52 44.0 3.29e-01 100.0% 67.0%
3926712 5001.1.1.44 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srv 0.52 44.0 3.06e-01 100.0% 52.5%
3926991 5001.1.1.66 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Srg 0.52 43.0 3.02e-01 100.0% 63.8%
3238096 5001.1.1.66 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Srg 0.52 43.0 3.08e-01 100.0% 68.3%
4995581 101.1.2.48 alpha arrays › HTH › HTH › winged helix domain › PadR 0.51 30.0 2.88e-01 79.7% 44.0%
1503101 2484.1.1.30 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Carbam_trans_N 0.51 44.0 3.21e-01 98.7% 95.3%
3216981 5001.1.1.66 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Srg 0.51 43.0 3.11e-01 100.0% 68.3%
3164764 2008.1.1.168 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PF30184 0.51 31.0 3.08e-01 81.0% 55.3%
3221030 5001.1.1.66 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Srg 0.51 43.0 3.02e-01 100.0% 68.4%
3828334 109.4.1.1254 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, E_motif 0.50 33.0 2.26e-01 83.5% 17.4%
3929773 5001.1.1.44 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srv 0.50 43.0 3.00e-01 100.0% 54.2%
3667879 101.1.2.386 alpha arrays › HTH › HTH › winged helix domain › WH_DRP 0.50 40.0 3.68e-01 87.3% 82.9%
5071269 101.1.2.48 alpha arrays › HTH › HTH › winged helix domain › PadR 0.50 31.0 2.34e-01 82.3% 22.9%
D3 medium residues 92-151
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00136.27 best DNA_pol_B 29.7 4.20e-07 96.7% 11.5%
CATH (55)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2rp4A00 6.10.280.60 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Transcription factor p53, C-terminal domain 0.90 68.0 6.34e-01 96.7% 66.2%
3ez0C00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.88 68.0 4.55e-01 81.7% 29.8%
3kr9A02 1.10.287.1890 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.88 63.0 6.32e-01 75.0% 75.4%
2wmmA01 1.20.5.420 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C 0.87 63.0 6.89e-01 75.0% 100.0%
4aifA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.86 70.0 5.13e-01 86.7% 36.1%
1zs3A00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.85 73.0 5.11e-01 100.0% 32.2%
2y39A00 1.20.120.1490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.85 78.0 6.20e-01 100.0% 53.6%
3tklB01 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.84 72.0 7.13e-01 100.0% 88.7%
4gouA03 1.20.900.10 Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain 0.84 67.0 4.52e-01 85.0% 48.7%
3rkvA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.83 66.0 4.89e-01 86.7% 35.4%
3qf7A02 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.82 72.0 7.07e-01 93.3% 92.1%
3fnbA01 1.20.1440.110 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › acylaminoacyl peptidase 0.80 64.0 5.08e-01 86.7% 44.7%
1yxrA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.80 67.0 6.19e-01 100.0% 73.0%
3d36B02 1.10.287.130 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain 0.80 67.0 6.74e-01 100.0% 90.2%
2itbB00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.79 67.0 4.61e-01 100.0% 28.3%
4h63K00 1.10.287.3490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.79 70.0 5.84e-01 100.0% 59.2%
3hiuD00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.79 67.0 4.92e-01 100.0% 36.8%
3zgxA02 6.10.140.1720 Special › Helix non-globular › Helix Hairpins › 0.78 68.0 5.92e-01 100.0% 63.7%
4e40A00 1.20.1260.80 Mainly Alpha › Up-down Bundle › Ferritin › 0.78 67.0 4.42e-01 96.7% 69.4%
3fppA03 6.10.140.1990 Special › Helix non-globular › Helix Hairpins › 0.78 71.0 6.20e-01 100.0% 87.5%
3behB01 1.20.120.540 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels 0.78 65.0 5.20e-01 100.0% 47.0%
1x4tA01 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.78 67.0 6.86e-01 100.0% 96.6%
1skvA00 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.78 68.0 6.64e-01 100.0% 89.1%
3pt1A02 1.20.930.60 Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › 0.77 68.0 5.42e-01 98.3% 70.8%
1wpaA01 6.10.140.340 Special › Helix non-globular › Helix Hairpins › 0.77 69.0 5.74e-01 100.0% 58.6%
3axjB02 1.20.58.200 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 0.77 58.0 5.14e-01 81.7% 56.5%
1k90B03 1.20.140.60 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › 0.77 61.0 4.93e-01 86.7% 46.1%
1rq0A01 6.10.140.160 Special › Helix non-globular › Helix Hairpins › 0.76 59.0 5.31e-01 83.3% 84.3%
5ux1D00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.76 66.0 4.54e-01 95.0% 57.4%
2yevA02 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.76 64.0 5.94e-01 98.3% 73.0%
7t7kA01 1.20.930.60 Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › 0.76 66.0 5.30e-01 98.3% 71.2%
2dw4A03 1.10.287.80 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain 0.75 68.0 5.69e-01 100.0% 63.4%
4cpgA00 1.20.5.420 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C 0.75 53.0 5.08e-01 76.7% 65.2%
1t7sA00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.74 66.0 5.13e-01 100.0% 48.8%
3hr0B01 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.74 66.0 6.00e-01 100.0% 75.9%
1tjlA00 1.20.120.910 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › DksA, coiled-coil domain 0.74 59.0 4.47e-01 100.0% 36.6%
4iggA01 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.74 59.0 5.72e-01 100.0% 80.6%
1zhcA00 6.10.280.50 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.73 64.0 5.92e-01 98.3% 77.6%
2p4vA01 1.10.287.180 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Transcription elongation factor, GreA/GreB, N-terminal domain 0.72 58.0 5.41e-01 100.0% 72.4%
2kmfA01 1.20.58.810 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Photosystem II Pbs27 0.72 53.0 4.48e-01 86.7% 47.1%
4asvA00 1.20.5.420 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C 0.71 50.0 4.57e-01 73.3% 55.7%
4hr1A00 1.20.1270.410 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.71 62.0 5.00e-01 100.0% 52.5%
3rm5B02 1.20.910.10 Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like 0.71 59.0 4.04e-01 100.0% 25.4%
2js5A00 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.70 59.0 5.62e-01 100.0% 80.3%
2l35A00 1.10.287.770 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like 0.70 56.0 5.59e-01 90.0% 88.9%
1vf7A03 1.10.287.470 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.70 63.0 6.31e-01 100.0% 100.0%
4pdyA02 3.90.1200.10 Alpha Beta › Alpha-Beta Complex › Aminoglycoside 3'-phosphotransferase; Chain: A, domain 2 › Aminoglycoside phosphotransferase (APH), C-terminal lobe 0.70 61.0 4.05e-01 96.7% 61.4%
3fxdB00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.69 53.0 5.43e-01 88.3% 93.1%
3gnlB02 1.10.287.1890 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.67 49.0 4.79e-01 81.7% 72.1%
4dyqA01 1.10.10.60 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like 0.66 49.0 4.22e-01 81.7% 49.5%
1wncB00 1.20.5.300 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.66 53.0 4.83e-01 100.0% 66.7%
3cqcB01 1.20.58.1380 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.65 51.0 4.53e-01 98.3% 58.9%
4okvE00 6.10.140.1890 Special › Helix non-globular › Helix Hairpins › 0.63 54.0 5.32e-01 100.0% 92.3%
1qguB04 1.20.89.10 Mainly Alpha › Up-down Bundle › Nitrogenase Molybdenum-iron Protein, subunit B; domain 4 › Nitrogenase Molybdenum-iron Protein, subunit B, domain 4 0.61 44.0 3.96e-01 76.7% 100.0%
3purA03 1.20.58.1360 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.56 46.0 3.95e-01 100.0% 58.2%
ECOD (75)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4970593 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.93 87.0 5.55e-01 100.0% 26.0%
3714352 4970.1.1.0 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I 0.92 77.0 6.00e-01 98.3% 45.0%
3397137 386.1.1.0 few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers 0.92 74.0 6.79e-01 86.7% 68.0%
4977369 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.91 85.0 5.41e-01 100.0% 26.0%
4939089 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.91 73.0 4.56e-01 85.0% 18.0%
4202466 192.6.1.0 alpha bundles › Long alpha-hairpin › Epsilon subunit of F1F0-ATP synthase C-terminal domain › Epsilon subunit of F1F0-ATP synthase C-terminal domain 0.91 65.0 7.48e-01 78.3% 100.0%
4959101 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.91 84.0 5.38e-01 100.0% 24.5%
3795985 622.4.1.0 alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related 0.90 73.0 6.44e-01 86.7% 62.4%
3348106 5076.2.1.10 alpha complex topology › Mitochondrial ADP/ATP carrier-like › Putative sulfate permease CysZ › Putative sulfate permease CysZ › PF29520 0.90 79.0 4.95e-01 100.0% 20.7%
5073476 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.90 83.0 5.40e-01 100.0% 26.4%
4956224 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.90 82.0 5.34e-01 100.0% 26.4%
3472169 4163.1.1.1 alpha bundles › GINS helical bundle-like › GINS helical bundle-like › PSF1 N-terminal domain-like › Sld5 0.90 77.0 5.51e-01 100.0% 35.5%
3993981 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.89 84.0 5.44e-01 100.0% 27.1%
3983659 4970.1.1.0 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I 0.89 66.0 6.47e-01 78.3% 72.3%
3676043 5076.2.1.10 alpha complex topology › Mitochondrial ADP/ATP carrier-like › Putative sulfate permease CysZ › Putative sulfate permease CysZ › PF29520 0.89 77.0 4.81e-01 100.0% 19.6%
3588519 101.1.2.49 alpha arrays › HTH › HTH › winged helix domain › PadR,Vir_act_alpha_C 0.89 73.0 5.18e-01 88.3% 35.2%
4958743 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.88 76.0 6.01e-01 100.0% 48.7%
2323867 4970.1.1.1 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.88 80.0 8.04e-01 98.3% 96.7%
4213046 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.88 75.0 7.31e-01 100.0% 84.6%
4999065 2484.1.1.124 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › OrfB_IS605 0.88 75.0 5.42e-01 100.0% 35.5%
4977784 2484.1.1.302 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB 0.88 74.0 4.79e-01 100.0% 23.0%
4999337 2484.1.1.124 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › OrfB_IS605 0.87 73.0 5.28e-01 98.3% 34.8%
4977429 2484.1.1.124 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › OrfB_IS605 0.87 74.0 5.50e-01 100.0% 39.3%
3651038 192.29.1.221 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › PF29520 0.87 75.0 5.72e-01 100.0% 43.1%
4485576 1.1.17.4 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Peptidase_S64 0.87 77.0 4.81e-01 95.0% 45.5%
4998819 2484.1.1.124 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › OrfB_IS605 0.87 74.0 5.62e-01 100.0% 42.3%
3642421 603.1.1.5 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin-6_N 0.86 74.0 5.70e-01 100.0% 44.0%
3491738 632.8.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 0.86 74.0 6.11e-01 100.0% 55.6%
3280999 101.1.2.135 alpha arrays › HTH › HTH › winged helix domain › MarR_2 0.86 74.0 5.35e-01 100.0% 36.1%
3681637 603.1.1.5 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin-6_N 0.86 73.0 5.10e-01 100.0% 31.4%
4674738 133.1.1.0 alpha bundles › DH domain-like › DBL homology domain (DH-domain) › DBL homology domain (DH-domain) 0.86 74.0 4.89e-01 100.0% 25.5%
4542284 109.4.1.210 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_19 0.85 62.0 4.14e-01 91.7% 21.5%
3346803 5076.2.1.10 alpha complex topology › Mitochondrial ADP/ATP carrier-like › Putative sulfate permease CysZ › Putative sulfate permease CysZ › PF29520 0.85 72.0 4.51e-01 100.0% 18.4%
4544002 192.6.1.1 alpha bundles › Long alpha-hairpin › Epsilon subunit of F1F0-ATP synthase C-terminal domain › Epsilon subunit of F1F0-ATP synthase C-terminal domain › ATP-synt_DE 0.85 66.0 7.13e-01 83.3% 98.0%
3192393 2004.1.1.430 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran, ABC_tran_Xtn 0.85 72.0 4.07e-01 100.0% 8.9%
3253283 192.5.1.14 alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › HR1_TOCA 0.85 74.0 6.21e-01 100.0% 58.9%
4978165 2484.1.1.124 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › OrfB_IS605 0.84 71.0 4.83e-01 100.0% 27.5%
4667859 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.84 74.0 5.84e-01 100.0% 49.6%
3286637 2484.1.1.124 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › OrfB_IS605 0.83 70.0 5.03e-01 100.0% 33.3%
4146694 192.29.1.277 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Dynamitin 0.83 71.0 6.91e-01 100.0% 84.6%
3755476 3755.1.1.0 alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related 0.83 72.0 5.06e-01 100.0% 32.0%
4972401 2484.1.1.124 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › OrfB_IS605 0.83 77.0 5.09e-01 100.0% 88.4%
222003 133.1.1.1 alpha bundles › DH domain-like › DBL homology domain (DH-domain) › DBL homology domain (DH-domain) › RhoGEF 0.83 67.0 4.59e-01 86.7% 51.3%
4883924 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.83 72.0 6.54e-01 100.0% 71.2%
2524047 601.14.1.1 alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin › Hemerythrin 0.83 74.0 5.25e-01 96.7% 79.6%
3732909 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.82 69.0 6.20e-01 100.0% 67.5%
4590389 4163.1.1.1 alpha bundles › GINS helical bundle-like › GINS helical bundle-like › PSF1 N-terminal domain-like › Sld5 0.82 68.0 5.00e-01 100.0% 35.5%
3894565 4207.1.2.65 alpha duplicates or obligate multimers › Mediator hinge subcomplex-like › Mediator hinge subcomplex-like › MED7 hinge region › OLF 0.82 70.0 4.19e-01 100.0% 14.0%
3796589 604.12.1.1 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT 0.82 68.0 5.66e-01 100.0% 54.0%
4349607 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.82 71.0 5.75e-01 100.0% 51.8%
3594586 192.7.1.0 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm 0.81 71.0 6.04e-01 100.0% 60.0%
3817615 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.81 70.0 5.78e-01 100.0% 54.3%
5048239 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.81 70.0 5.62e-01 96.7% 65.2%
3356933 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.81 70.0 5.05e-01 100.0% 36.1%
3742811 604.6.1.1 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › GAT 0.80 67.0 5.40e-01 91.7% 49.6%
4961346 3805.1.1.1 alpha bundles › Hypothetical protein TTHB059 › Hypothetical protein TTHB059 › Hypothetical protein TTHB059 › DUF3209 0.80 68.0 5.37e-01 100.0% 46.7%
4951260 601.14.1.1 alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin › Hemerythrin 0.80 70.0 5.29e-01 100.0% 41.4%
3386700 304.58.1.0 a+b two layers › Alpha-beta plaits › FepE-like › FepE-like 0.80 74.0 4.59e-01 100.0% 21.7%
3580316 4082.1.1.0 alpha duplicates or obligate multimers › Hairy Orange domain › Hairy Orange domain › Hairy Orange domain 0.80 56.0 6.27e-01 75.0% 100.0%
3615269 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.80 69.0 4.64e-01 100.0% 27.1%
5005724 3755.3.1.637 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DUF7121 0.80 73.0 4.73e-01 98.3% 100.0%
3224003 9001.1.1.3 alpha bundles › TMEM120/ELO/TLC › TMEM120/ELO/TLC › TMEM120/ELO/TLC › TMPIT 0.79 67.0 6.13e-01 100.0% 71.2%
3622515 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.79 67.0 5.95e-01 100.0% 65.9%
3931593 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.79 64.0 5.80e-01 100.0% 66.3%
3718782 10.12.1.0 beta sandwiches › jelly-roll › Double-stranded beta-helix › Double-stranded beta-helix 0.78 62.0 4.13e-01 86.7% 26.1%
4396464 605.1.1.305 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › Exonuc_VII_S 0.78 65.0 6.58e-01 100.0% 91.7%
4541195 3755.3.1.470 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › T3SSipB 0.78 68.0 5.21e-01 100.0% 43.8%
3271963 133.1.1.1 alpha bundles › DH domain-like › DBL homology domain (DH-domain) › DBL homology domain (DH-domain) › RhoGEF 0.78 61.0 4.46e-01 86.7% 33.3%
3259629 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.77 63.0 5.36e-01 100.0% 55.0%
3578008 601.1.2.100 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › PF31009 0.76 63.0 4.67e-01 100.0% 36.1%
3799484 633.26.1.3 alpha bundles › Bromodomain-like › SidC lipid-binding domain › SidC lipid-binding domain › PF31009 0.76 63.0 4.58e-01 100.0% 33.9%
3970799 602.3.1.0 alpha arrays › L-aspartase middle domain-like › TssK neck domain › TssK neck domain 0.74 64.0 5.14e-01 98.3% 51.7%
5020701 3755.3.1.637 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DUF7121 0.72 65.0 4.27e-01 100.0% 25.1%
3786466 601.1.2.75 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › PTPLA 0.72 60.0 4.13e-01 98.3% 26.5%
2914508 2004.1.1.5 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran 0.71 54.0 3.49e-01 85.0% 17.6%
D4 medium residues 262-338
PDB
Domain cluster: representative
CATH (2)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4kzsA02 6.10.140.1870 Special › Helix non-globular › Helix Hairpins › 0.59 41.0 4.30e-01 71.4% 80.0%
2odvA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.51 37.0 3.37e-01 79.2% 67.0%
ECOD (2)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3212006 601.24.1.0 alpha bundles › Four-helical up-and-down bundle › FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) › FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) 0.56 43.0 3.67e-01 84.4% 63.1%
3390993 601.7.1.21 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › NICE-3 0.51 37.0 3.49e-01 83.1% 63.2%