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SRR1747052_scaffold_19_prodigal-single.1__X__X__00049
Bact-VirSRR1747052_scaffold_19_prodigal-single.1__X__X__00049
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 334-425
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF09481.16 best | CRISPR_Cse1 | 25.2 | 1.40e-05 | 100.0% | 19.4% |
CATH (8)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4mt4A00 | 1.20.1600.10 | Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) | 0.58 | 45.0 | 2.88e-01 | 82.6% | 90.5% |
| 5jpnB02 | 2.20.130.20 | Mainly Beta › Single Sheet › S-adenosyl-L-methionine-dependent methyltransferases › | 0.58 | 28.0 | 3.41e-01 | 85.9% | 69.0% |
| 1ek9A00 | 1.20.1600.10 | Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) | 0.51 | 37.0 | 2.41e-01 | 76.1% | 68.7% |
| 2xssA00 | 3.30.450.40 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › GAF domain | 0.51 | 30.0 | 2.58e-01 | 97.8% | 32.1% |
| 1hq6B00 | 3.50.20.10 | Alpha Beta › 3-Layer(bba) Sandwich › Pyruvoyl-Dependent Histidine Decarboxylase; Chain B › Pyruvoyl-Dependent Histidine Decarboxylase, subunit B | 0.51 | 40.0 | 3.06e-01 | 85.9% | 76.8% |
| 4k3bA04 | 3.10.20.310 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › membrane protein fhac | 0.51 | 30.0 | 3.18e-01 | 85.9% | 64.1% |
| 3hrzB01 | 2.20.130.20 | Mainly Beta › Single Sheet › S-adenosyl-L-methionine-dependent methyltransferases › | 0.51 | 31.0 | 3.41e-01 | 85.9% | 75.0% |
| 1d6uA03 | 2.70.98.20 | Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › Copper amine oxidase, catalytic domain | 0.50 | 41.0 | 2.76e-01 | 92.4% | 82.2% |
ECOD (18)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1489431 | 3576.1.1.0 ↗ | a+b complex topology › Cas8-like › Cascade subunit CasA/Cse1/Cas8 › Cascade subunit CasA/Cse1/Cas8 | 0.84 | 79.0 | 4.75e-01 | 100.0% | 19.9% |
| 4857423 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.68 | 41.0 | 4.11e-01 | 80.4% | 58.5% |
| 4059004 | 67.1.1.0 ↗ | beta sandwiches › HSP40/DnaJ peptide-binding domain › HSP40/DnaJ peptide-binding domain › HSP40/DnaJ peptide-binding domain | 0.64 | 38.0 | 3.83e-01 | 81.5% | 56.8% |
| 1391879 | 11.1.1.6 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › A2M | 0.60 | 32.0 | 3.35e-01 | 84.8% | 53.6% |
| 3937781 | 2006.1.6.0 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like | 0.59 | 38.0 | 2.97e-01 | 87.0% | 28.8% |
| 3943722 | 5085.1.1.1 ↗ | a+b duplicates or obligate multimers › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) › OEP | 0.58 | 42.0 | 2.75e-01 | 77.2% | 93.7% |
| 4629529 | 2002.1.1.420 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › HpcH_HpaI, PF25918 | 0.56 | 48.0 | 3.17e-01 | 96.7% | 34.8% |
| 3447934 | 263.1.1.1 ↗ | a+b three layers › SRF-like › SRF-like › SRF-like › SRF-TF | 0.55 | 32.0 | 3.17e-01 | 85.9% | 52.0% |
| 4961538 | 2002.1.1.256 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › MSH_C | 0.54 | 47.0 | 3.07e-01 | 97.8% | 36.3% |
| 3959362 | 101.1.1.531 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › WS_DGAT_cat | 0.53 | 39.0 | 3.36e-01 | 91.3% | 47.3% |
| 3701672 | 2004.1.1.26 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Kinesin | 0.53 | 35.0 | 2.90e-01 | 84.8% | 35.3% |
| 3367010 | 2004.1.1.26 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Kinesin | 0.53 | 36.0 | 2.92e-01 | 83.7% | 36.6% |
| 1411401 | 304.48.1.7 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Flu_PB1 | 0.52 | 42.0 | 2.79e-01 | 94.6% | 80.1% |
| 4878479 | 323.1.1.5 ↗ | a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › Condensation | 0.52 | 40.0 | 3.93e-01 | 90.2% | 76.0% |
| 5020776 | 3281.1.1.1 ↗ | alpha complex topology › Sodium/proton antiporter subunits-like › Sodium/proton antiporter subunits-like › NADH-quinone oxidoreductase subunit L (NuoL)-related › Proton_antipo_M | 0.52 | 42.0 | 2.62e-01 | 91.3% | 51.9% |
| 3466392 | 11.2.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain | 0.51 | 39.0 | 3.57e-01 | 80.4% | 95.8% |
| 4245552 | 67.1.1.1 ↗ | beta sandwiches › HSP40/DnaJ peptide-binding domain › HSP40/DnaJ peptide-binding domain › HSP40/DnaJ peptide-binding domain › DnaJ_C | 0.50 | 30.0 | 3.02e-01 | 85.9% | 56.7% |
| 3839154 | 3121.1.1.1 ↗ | a+b duplicates or obligate multimers › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › POTRA | 0.50 | 29.0 | 3.05e-01 | 83.7% | 57.6% |
D2
high
residues 429-564
Domain cluster:
representative
CATH (59)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3wvoC02 | 1.10.132.100 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › | 0.84 | 76.0 | 7.84e-01 | 95.6% | 98.5% |
| 6tkvA01 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.76 | 37.0 | 5.14e-01 | 99.3% | 94.1% |
| 3onjA00 | 1.20.58.400 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins | 0.76 | 38.0 | 4.47e-01 | 100.0% | 68.0% |
| 1lvfB00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.72 | 36.0 | 4.13e-01 | 100.0% | 63.5% |
| 2x4hA00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.63 | 37.0 | 3.84e-01 | 88.2% | 61.2% |
| 3i2wA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.62 | 43.0 | 3.55e-01 | 71.3% | 84.9% |
| 4cmyA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.62 | 49.0 | 4.61e-01 | 100.0% | 69.3% |
| 1yuzB01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.62 | 47.0 | 4.76e-01 | 100.0% | 79.7% |
| 3fseB02 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.62 | 48.0 | 4.77e-01 | 100.0% | 78.5% |
| 3dyjA02 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.62 | 40.0 | 3.93e-01 | 72.1% | 59.6% |
| 4ceiA03 | 6.10.250.2380 | Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.62 | 46.0 | 5.04e-01 | 97.8% | 95.5% |
| 3wmeA01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.61 | 51.0 | 3.91e-01 | 90.4% | 87.5% |
| 2chpA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.60 | 47.0 | 4.62e-01 | 100.0% | 77.0% |
| 2ib0A01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.60 | 45.0 | 4.57e-01 | 98.5% | 80.0% |
| 3rq9A00 | 1.10.287.2500 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.60 | 31.0 | 3.89e-01 | 84.6% | 83.3% |
| 3e6sA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.59 | 50.0 | 4.76e-01 | 100.0% | 78.6% |
| 2c41C01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.59 | 47.0 | 4.60e-01 | 98.5% | 77.9% |
| 4l8iB00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.59 | 45.0 | 4.89e-01 | 77.9% | 100.0% |
| 2oexA02 | 1.20.140.50 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › alix/aip1 like domains | 0.58 | 42.0 | 3.73e-01 | 74.3% | 87.3% |
| 1x04A00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.58 | 42.0 | 3.72e-01 | 74.3% | 87.0% |
| 3nyjA00 | 1.20.120.770 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Amyloid precursor protein, E2 domain | 0.58 | 41.0 | 3.77e-01 | 72.8% | 55.2% |
| 5wp3B00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.58 | 42.0 | 4.81e-01 | 78.7% | 100.0% |
| 1tjoB00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.58 | 47.0 | 4.37e-01 | 100.0% | 68.6% |
| 3r2kA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.58 | 47.0 | 4.55e-01 | 100.0% | 77.9% |
| 2z1qB04 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.58 | 45.0 | 4.56e-01 | 91.9% | 82.4% |
| 3zsuA00 | 1.20.120.290 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle | 0.58 | 39.0 | 4.15e-01 | 77.2% | 78.0% |
| 3ajmB02 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.58 | 44.0 | 4.45e-01 | 100.0% | 80.5% |
| 1lkoA01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.58 | 44.0 | 4.39e-01 | 100.0% | 76.6% |
| 8ek4A01 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.58 | 41.0 | 4.23e-01 | 73.5% | 98.5% |
| 5d91A02 | 1.20.120.1760 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CDP-alcohol phosphotransferase transmembrane (TM) domain | 0.58 | 41.0 | 3.67e-01 | 73.5% | 77.3% |
| 2ot4A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.58 | 41.0 | 4.55e-01 | 75.0% | 92.5% |
| 3cazB00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.58 | 45.0 | 3.90e-01 | 82.4% | 89.0% |
| 3g9gA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.57 | 41.0 | 3.41e-01 | 75.0% | 78.8% |
| 1cnt200 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.56 | 36.0 | 3.74e-01 | 92.6% | 66.9% |
| 7dl9B02 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.56 | 50.0 | 4.44e-01 | 100.0% | 98.0% |
| 6o0aA01 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.56 | 44.0 | 4.27e-01 | 80.9% | 92.6% |
| 1t72A02 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.56 | 38.0 | 4.41e-01 | 79.4% | 96.9% |
| 3m9vA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.56 | 47.0 | 4.59e-01 | 94.9% | 87.9% |
| 6tqfA01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.56 | 43.0 | 3.19e-01 | 83.8% | 81.6% |
| 4iloA00 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.55 | 35.0 | 2.90e-01 | 100.0% | 36.0% |
| 8ex5A01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.55 | 49.0 | 4.42e-01 | 99.3% | 96.3% |
| 5ux2B01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.55 | 45.0 | 3.91e-01 | 95.6% | 56.5% |
| 5cofA00 | 1.20.120.450 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › dinb family like domain | 0.55 | 50.0 | 4.62e-01 | 99.3% | 79.7% |
| 1oahA02 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.55 | 42.0 | 4.16e-01 | 89.0% | 76.8% |
| 2yzsA02 | 1.20.120.920 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CRISPR-associated endonuclease Cas1, C-terminal domain | 0.54 | 42.0 | 3.51e-01 | 97.1% | 47.8% |
| 4oydB00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.54 | 41.0 | 4.44e-01 | 80.1% | 97.4% |
| 1h7cA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.54 | 33.0 | 3.75e-01 | 100.0% | 79.6% |
| 2rd3D00 | 1.20.910.10 | Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like | 0.54 | 48.0 | 4.16e-01 | 99.3% | 83.9% |
| 1wdzA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.54 | 39.0 | 3.34e-01 | 75.0% | 87.9% |
| 3p4tA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.54 | 46.0 | 4.52e-01 | 95.6% | 93.3% |
| 1fewA00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.54 | 40.0 | 3.69e-01 | 77.2% | 75.7% |
| 6p73A02 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.53 | 39.0 | 3.89e-01 | 76.5% | 79.0% |
| 1sziA02 | 1.20.120.340 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS | 0.53 | 37.0 | 3.71e-01 | 73.5% | 69.3% |
| 1b48A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.53 | 35.0 | 3.83e-01 | 77.2% | 82.6% |
| 6wk3A00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.52 | 40.0 | 3.95e-01 | 79.4% | 92.4% |
| 1h6gA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.52 | 36.0 | 3.81e-01 | 79.4% | 79.8% |
| 1t72A01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.51 | 38.0 | 4.10e-01 | 77.2% | 91.5% |
| 3caxA01 | 1.20.120.520 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › nmb1532 protein domain like | 0.51 | 40.0 | 3.51e-01 | 86.0% | 54.4% |
| 3owaA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.50 | 43.0 | 4.07e-01 | 95.6% | 92.4% |
ECOD (49)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3283013 | 3576.1.1.1 ↗ | a+b complex topology › Cas8-like › Cascade subunit CasA/Cse1/Cas8 › Cascade subunit CasA/Cse1/Cas8 › CRISPR_Cse1 | 0.89 | 79.0 | 5.12e-01 | 92.6% | 25.8% |
| 1489431 | 3576.1.1.0 ↗ | a+b complex topology › Cas8-like › Cascade subunit CasA/Cse1/Cas8 › Cascade subunit CasA/Cse1/Cas8 | 0.83 | 77.0 | 4.91e-01 | 95.6% | 23.9% |
| 3624654 | 1075.1.1.4 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane_3 | 0.62 | 45.0 | 3.71e-01 | 75.7% | 54.2% |
| 3473212 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.62 | 51.0 | 3.58e-01 | 88.2% | 58.2% |
| 3476998 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.62 | 55.0 | 4.65e-01 | 97.1% | 83.6% |
| 3236000 | 5001.1.1.27 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Sre | 0.62 | 55.0 | 4.28e-01 | 100.0% | 65.1% |
| 4541523 | 5001.1.1.119 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › PF27607 | 0.61 | 55.0 | 4.24e-01 | 100.0% | 53.9% |
| 5060908 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.60 | 51.0 | 5.01e-01 | 91.9% | 99.3% |
| 3506187 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.60 | 52.0 | 4.61e-01 | 97.1% | 94.6% |
| 3234449 | 5001.1.1.41 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srw | 0.59 | 52.0 | 3.96e-01 | 96.3% | 59.1% |
| 4274798 | 5050.1.1.25 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › TLC | 0.59 | 52.0 | 4.29e-01 | 94.1% | 86.4% |
| 3439292 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.59 | 55.0 | 4.87e-01 | 100.0% | 80.5% |
| 3504805 | 3291.1.1.1 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Snf7 | 0.59 | 41.0 | 4.08e-01 | 70.6% | 97.9% |
| 3214737 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.59 | 52.0 | 4.33e-01 | 100.0% | 60.0% |
| 2849693 | 1075.4.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane | 0.58 | 49.0 | 3.70e-01 | 90.4% | 86.8% |
| 4347866 | 3896.1.1.1 ↗ | alpha duplicates or obligate multimers › Intramembrane CDP-DAG synthetase-related › Intramembrane CDP-DAG synthetase-related › Intramembrane CDP-DAG synthetase › CTP_transf_1 | 0.58 | 50.0 | 4.01e-01 | 97.8% | 46.0% |
| 56672 | 150.3.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › 4-helical cytokines › 4-helical cytokine | 0.57 | 41.0 | 4.06e-01 | 99.3% | 68.5% |
| 3721567 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.57 | 51.0 | 4.25e-01 | 100.0% | 83.7% |
| 3720301 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.57 | 50.0 | 4.45e-01 | 97.1% | 90.5% |
| 3586164 | 7015.1.1.0 ↗ | alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain | 0.57 | 45.0 | 4.62e-01 | 91.9% | 89.2% |
| 3726328 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.56 | 51.0 | 4.38e-01 | 99.3% | 89.3% |
| 3629560 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.56 | 50.0 | 4.83e-01 | 100.0% | 91.6% |
| 3840961 | 1075.4.1.2 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane_2 | 0.56 | 46.0 | 3.45e-01 | 88.2% | 83.1% |
| 4937550 | 1075.1.1.3 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane_2 | 0.56 | 41.0 | 3.24e-01 | 75.7% | 85.3% |
| 5016444 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.56 | 49.0 | 4.40e-01 | 100.0% | 96.6% |
| 4973923 | 1075.4.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold | 0.56 | 49.0 | 3.69e-01 | 94.9% | 52.7% |
| 3787233 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.56 | 50.0 | 3.89e-01 | 100.0% | 44.7% |
| 3480875 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.55 | 48.0 | 4.08e-01 | 99.3% | 92.2% |
| 4888150 | 1075.4.1.9 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_tran+ABC_membrane | 0.55 | 49.0 | 3.71e-01 | 97.1% | 53.2% |
| 3999032 | 3615.1.1.0 ↗ | alpha bundles › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain | 0.55 | 49.0 | 4.70e-01 | 98.5% | 96.8% |
| 3812632 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.55 | 49.0 | 4.20e-01 | 99.3% | 81.8% |
| 3699080 | 604.5.1.36 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › UPF0220 | 0.55 | 46.0 | 4.65e-01 | 89.0% | 91.1% |
| 3475603 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.55 | 47.0 | 4.06e-01 | 94.9% | 99.5% |
| 4631214 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.55 | 49.0 | 4.56e-01 | 100.0% | 77.6% |
| 3513855 | 633.23.1.22 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin › MARVEL | 0.54 | 49.0 | 4.81e-01 | 99.3% | 97.9% |
| 3206406 | 633.4.1.0 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor | 0.54 | 44.0 | 4.24e-01 | 97.8% | 75.2% |
| 2322486 | 1075.4.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane | 0.54 | 45.0 | 3.51e-01 | 90.4% | 86.6% |
| 3935757 | 7015.1.1.1 ↗ | alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › DHHC | 0.54 | 46.0 | 4.48e-01 | 97.1% | 84.7% |
| 3171827 | 192.29.1.4 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Opi1 | 0.54 | 38.0 | 3.84e-01 | 73.5% | 71.9% |
| 4411856 | 632.22.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › EzrA | 0.54 | 35.0 | 4.04e-01 | 70.6% | 93.7% |
| 3185438 | 603.1.1.97 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin, SNARE | 0.53 | 48.0 | 4.24e-01 | 99.3% | 95.0% |
| 4937528 | 603.2.1.0 ↗ | alpha bundles › STAT-like › STAT › STAT | 0.52 | 35.0 | 3.32e-01 | 76.5% | 53.1% |
| 3923557 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.52 | 36.0 | 3.14e-01 | 100.0% | 47.5% |
| 3755879 | 601.1.2.110 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Tweety | 0.52 | 46.0 | 3.67e-01 | 97.8% | 62.9% |
| 3590328 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.51 | 46.0 | 4.21e-01 | 100.0% | 100.0% |
| 5041130 | 601.14.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin | 0.51 | 43.0 | 4.45e-01 | 91.9% | 100.0% |
| 3495625 | 133.1.1.1 ↗ | alpha bundles › DH domain-like › DBL homology domain (DH-domain) › DBL homology domain (DH-domain) › RhoGEF | 0.51 | 44.0 | 3.69e-01 | 97.1% | 74.6% |
| 3816971 | 3755.3.1.285 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › NET2A | 0.50 | 35.0 | 3.27e-01 | 73.5% | 57.6% |
| 3358116 | 1075.4.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane | 0.50 | 42.0 | 3.30e-01 | 92.6% | 62.3% |
D3
medium
residues 14-118_210-231
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF09481.16 best | CRISPR_Cse1 | 85.7 | 5.90e-24 | 77.2% | 21.4% |
CATH (7)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4wcgA00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.54 | 24.0 | 3.30e-01 | 85.0% | 83.6% |
| 6az1a00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.54 | 27.0 | 3.38e-01 | 87.4% | 81.9% |
| 2wfgA00 | 3.90.740.10 | Alpha Beta › Alpha-Beta Complex › Isoleucyl-tRNA Synthetase; domain 2 › Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain | 0.52 | 38.0 | 3.07e-01 | 77.2% | 76.4% |
| 4kmfA00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.51 | 25.0 | 3.28e-01 | 83.5% | 90.3% |
| 2x1dA02 | 1.10.10.2120 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › | 0.51 | 25.0 | 3.14e-01 | 78.7% | 77.0% |
| 2fj0A01 | 3.40.50.1820 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain | 0.51 | 39.0 | 2.66e-01 | 84.3% | 42.6% |
| 1yhuB00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.50 | 33.0 | 3.21e-01 | 87.4% | 59.0% |
ECOD (15)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 999868 | 3576.1.1.0 ↗ | a+b complex topology › Cas8-like › Cascade subunit CasA/Cse1/Cas8 › Cascade subunit CasA/Cse1/Cas8 | 0.94 | 88.0 | 5.60e-01 | 96.9% | 39.8% |
| 1489431 | 3576.1.1.0 ↗ | a+b complex topology › Cas8-like › Cascade subunit CasA/Cse1/Cas8 › Cascade subunit CasA/Cse1/Cas8 | 0.94 | 88.0 | 5.52e-01 | 96.9% | 40.5% |
| 223980 | 3576.1.1.0 ↗ | a+b complex topology › Cas8-like › Cascade subunit CasA/Cse1/Cas8 › Cascade subunit CasA/Cse1/Cas8 | 0.92 | 85.0 | 5.51e-01 | 95.3% | 64.7% |
| 2388890 | 3576.1.1.0 ↗ | a+b complex topology › Cas8-like › Cascade subunit CasA/Cse1/Cas8 › Cascade subunit CasA/Cse1/Cas8 | 0.89 | 81.0 | 5.18e-01 | 95.3% | 66.7% |
| 3979217 | 3576.1.1.1 ↗ | a+b complex topology › Cas8-like › Cascade subunit CasA/Cse1/Cas8 › Cascade subunit CasA/Cse1/Cas8 › CRISPR_Cse1 | 0.86 | 79.0 | 5.05e-01 | 96.1% | 68.0% |
| 3283013 | 3576.1.1.1 ↗ | a+b complex topology › Cas8-like › Cascade subunit CasA/Cse1/Cas8 › Cascade subunit CasA/Cse1/Cas8 › CRISPR_Cse1 | 0.83 | 79.0 | 5.04e-01 | 100.0% | 42.1% |
| 3986601 | 101.1.2.142 ↗ | alpha arrays › HTH › HTH › winged helix domain › HTH_Crp_2 | 0.56 | 32.0 | 3.85e-01 | 75.6% | 86.3% |
| 4971705 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.56 | 23.0 | 2.95e-01 | 84.3% | 61.3% |
| 4996857 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.56 | 23.0 | 3.22e-01 | 85.8% | 78.0% |
| 4211717 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.55 | 29.0 | 3.45e-01 | 70.1% | 77.5% |
| 3986875 | 4254.1.1.1 ↗ | alpha arrays › YoaC-like › YoaC-like › YoaC-like › DUF1889 | 0.54 | 29.0 | 3.63e-01 | 74.0% | 87.7% |
| 4010642 | 101.1.2.6 ↗ | alpha arrays › HTH › HTH › winged helix domain › GntR | 0.54 | 28.0 | 3.58e-01 | 71.7% | 90.0% |
| 3944078 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.53 | 28.0 | 3.52e-01 | 71.7% | 90.0% |
| 4942687 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.53 | 28.0 | 3.40e-01 | 88.2% | 80.0% |
| 4969624 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.50 | 27.0 | 3.46e-01 | 87.4% | 92.9% |
D4
medium
residues 119-148_232-292_317-333
Domain cluster:
representative
D5
medium
residues 149-209_293-316
Domain cluster:
representative
CATH (2)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2xs2A00 | 3.30.70.330 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain | 0.63 | 35.0 | 3.55e-01 | 87.1% | 52.9% |
| 5w0hA00 | 3.30.70.330 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain | 0.60 | 34.0 | 3.54e-01 | 88.2% | 57.5% |