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STL6-S73_scaffold_1_prodigal-single.1__X__X__00080

Bact-Vir

STL6-S73_scaffold_1_prodigal-single.1__X__X__00080

Identity

Kingdom:
phage

Quality

64.5 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 149-227
PDB
Domain cluster: representative
CATH (38)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2g2qB01 3.40.30.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin 0.65 52.0 4.69e-01 89.9% 92.1%
2a1vA00 3.90.1150.30 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › 0.60 52.0 4.43e-01 100.0% 85.5%
1r7lA00 3.30.2120.10 Alpha Beta › 2-Layer Sandwich › Bacillus phage protein › Bacillus phage protein-like 0.60 41.0 3.80e-01 83.5% 54.4%
4l0mA00 3.40.50.1580 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nucleoside phosphorylase domain 0.59 47.0 3.48e-01 89.9% 97.9%
4fd0A01 2.60.40.3630 Mainly Beta › Sandwich › Immunoglobulin-like › 0.58 40.0 4.09e-01 72.2% 77.2%
1b8pA02 3.90.110.10 Alpha Beta › Alpha-Beta Complex › L-2-Hydroxyisocaproate Dehydrogenase; Chain A, domain 2 › Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal 0.58 40.0 3.25e-01 73.4% 48.8%
4hbrA00 3.10.450.360 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.58 40.0 3.41e-01 92.4% 40.7%
3g7qA01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.58 46.0 3.73e-01 87.3% 62.8%
4ms4B02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.57 49.0 3.84e-01 100.0% 96.1%
2ltrA00 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.57 45.0 4.16e-01 88.6% 69.5%
1qa7A01 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.56 43.0 3.85e-01 81.0% 80.0%
6gfaA02 3.30.30.30 Alpha Beta › 2-Layer Sandwich › Defensin A-like › 0.56 33.0 3.80e-01 88.6% 82.1%
3cbfA01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.56 48.0 3.80e-01 98.7% 56.6%
1uh9A02 2.40.70.10 Mainly Beta › Beta Barrel › Cathepsin D, subunit A; domain 1 › Acid Proteases 0.56 41.0 3.41e-01 78.5% 83.9%
7tbdB02 2.40.70.10 Mainly Beta › Beta Barrel › Cathepsin D, subunit A; domain 1 › Acid Proteases 0.55 41.0 3.33e-01 81.0% 81.0%
2fokA03 3.40.91.30 Alpha Beta › 3-Layer(aba) Sandwich › Restriction Endonuclease › 0.55 44.0 3.49e-01 91.1% 85.1%
1am5A02 2.40.70.10 Mainly Beta › Beta Barrel › Cathepsin D, subunit A; domain 1 › Acid Proteases 0.55 40.0 3.36e-01 81.0% 84.9%
3k1lA01 3.30.457.40 Alpha Beta › 2-Layer Sandwich › Copper Amine Oxidase; Chain A, domain 1 › 0.55 43.0 4.20e-01 89.9% 98.9%
3k6kA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.54 47.0 3.23e-01 100.0% 72.7%
6d0aA03 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.54 44.0 4.01e-01 96.2% 86.1%
1rtqA00 3.40.630.10 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Zn peptidases 0.53 44.0 3.12e-01 97.5% 33.3%
1sr4B00 3.60.10.10 Alpha Beta › 4-Layer Sandwich › Deoxyribonuclease I; Chain A › Endonuclease/exonuclease/phosphatase 0.53 41.0 2.98e-01 87.3% 91.9%
2v5oA03 2.70.130.10 Mainly Beta › Distorted Sandwich › Cation-dependent Mannose-6-phosphate Receptor; Chain A › Mannose-6-phosphate receptor binding domain 0.52 42.0 3.62e-01 93.7% 88.4%
3ga7A00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.52 36.0 2.50e-01 73.4% 32.8%
3uuwB02 3.30.360.10 Alpha Beta › 2-Layer Sandwich › Dihydrodipicolinate Reductase; domain 2 › Dihydrodipicolinate Reductase; domain 2 0.52 41.0 3.20e-01 87.3% 37.5%
3dxpA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.52 42.0 4.02e-01 91.1% 100.0%
5xbfA03 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.52 38.0 3.71e-01 78.5% 72.7%
1lc0A02 3.30.360.10 Alpha Beta › 2-Layer Sandwich › Dihydrodipicolinate Reductase; domain 2 › Dihydrodipicolinate Reductase; domain 2 0.52 42.0 3.54e-01 94.9% 50.3%
3n7cA00 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.51 39.0 3.55e-01 82.3% 76.9%
4bdxA00 2.10.25.10 Mainly Beta › Ribbon › Laminin › Laminin 0.51 29.0 2.87e-01 92.4% 47.0%
2dmyA00 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.51 41.0 3.92e-01 89.9% 79.4%
1x1fA00 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.51 38.0 3.09e-01 78.5% 50.3%
3vpzA02 3.40.367.20 Alpha Beta › 3-Layer(aba) Sandwich › Hexokinase; domain 1 › 0.51 40.0 3.13e-01 89.9% 89.0%
3licA01 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.51 35.0 2.80e-01 72.2% 85.4%
4chjA00 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.51 40.0 3.49e-01 86.1% 66.1%
2wb8A01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.51 37.0 3.00e-01 78.5% 82.6%
2douB01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.50 41.0 3.45e-01 94.9% 60.4%
4nehA01 2.130.10.130 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › Integrin alpha, N-terminal 0.50 41.0 2.75e-01 97.5% 25.6%
ECOD (52)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4028916 241.15.1.0 ↗ a+b two layers › Type III secretory system chaperone-like › FP (Fbxo7/PI31) dimerization domain › FP (Fbxo7/PI31) dimerization domain 0.75 66.0 5.96e-01 98.7% 90.0%
3498714 241.15.1.3 ↗ a+b two layers › Type III secretory system chaperone-like › FP (Fbxo7/PI31) dimerization domain › FP (Fbxo7/PI31) dimerization domain › SPC25 0.73 64.0 5.62e-01 96.2% 93.9%
3785991 241.15.1.3 ↗ a+b two layers › Type III secretory system chaperone-like › FP (Fbxo7/PI31) dimerization domain › FP (Fbxo7/PI31) dimerization domain › SPC25 0.73 63.0 5.77e-01 96.2% 90.4%
3632230 241.15.1.3 ↗ a+b two layers › Type III secretory system chaperone-like › FP (Fbxo7/PI31) dimerization domain › FP (Fbxo7/PI31) dimerization domain › SPC25 0.71 62.0 5.61e-01 98.7% 96.4%
4243492 243.3.1.3 ↗ a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin › PepSY 0.63 45.0 4.94e-01 88.6% 98.3%
5023930 330.1.1.0 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.62 46.0 4.51e-01 87.3% 72.9%
2602613 7520.1.1.2 ↗ a/b three-layered sandwiches › CinA-like › CinA-like › CinA-like › HcgF 0.62 52.0 4.17e-01 96.2% 94.7%
4023919 252.2.1.1 ↗ a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like › AP2 0.61 45.0 4.85e-01 92.4% 98.5%
4027687 330.3.1.0 ↗ a+b two layers › dsRBD-like › Peptidyl-tRNA hydrolase domain-like › Peptidyl-tRNA hydrolase domain-like 0.61 41.0 4.66e-01 88.6% 100.0%
3964101 243.3.1.3 ↗ a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin › PepSY 0.61 42.0 4.66e-01 87.3% 96.7%
5040467 2003.1.5.4 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › PCMT 0.61 43.0 3.05e-01 74.7% 58.4%
4015358 7579.1.1.49 ↗ a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › GCE_fung 0.61 45.0 2.98e-01 81.0% 27.3%
5826 330.5.1.2 ↗ a+b two layers › dsRBD-like › Bacillus phage protein › Bacillus phage protein › Phage_ABA_S 0.60 41.0 3.80e-01 83.5% 54.4%
3730089 64.1.1.0 ↗ beta meanders › WW domain-like › WW domain › WW domain 0.60 33.0 3.99e-01 79.7% 85.7%
3782710 1.1.1.1 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › Asp 0.60 45.0 2.95e-01 81.0% 37.4%
3589974 220.1.1.0 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like 0.59 48.0 4.00e-01 91.1% 56.6%
4323652 330.1.1.1 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › dsrm 0.59 44.0 4.05e-01 86.1% 61.0%
3806474 386.1.1.0 ↗ few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers 0.59 32.0 3.85e-01 81.0% 100.0%
4669225 2008.1.1.104 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Cap4_nuclease 0.58 40.0 3.25e-01 73.4% 71.9%
4337720 3454.1.1.2 ↗ beta barrels › GspC HR domain/PilP-like › GspC HR domain/PilP-like › GspC HR domain/PilP-like › T2SSC 0.57 32.0 3.44e-01 73.4% 63.1%
3709800 330.1.1.0 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.56 47.0 4.44e-01 93.7% 85.3%
4995786 3153.1.1.0 ↗ a+b two layers › PipX › PipX › PipX 0.55 35.0 3.48e-01 91.1% 58.8%
4033432 243.3.1.3 ↗ a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin › PepSY 0.55 39.0 4.29e-01 83.5% 100.0%
4237612 3006.1.1.6 ↗ a+b two layers › Sm-Like archaeal protein Smap3, C-terminal domain › Sm-Like archaeal protein Smap3, C-terminal domain › Sm-Like archaeal protein Smap3, C-terminal domain › CPSF73-100_C 0.55 42.0 4.18e-01 92.4% 77.6%
3929033 59.1.1.0 ↗ beta complex topology › triple barrel › triple barrel › Rap30/74 interaction domains-like 0.55 37.0 3.75e-01 72.2% 68.8%
5082597 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.55 39.0 3.10e-01 75.9% 65.1%
4943724 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.55 44.0 2.89e-01 87.3% 24.9%
4483491 2004.1.1.73 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MMR_HSR1 0.55 46.0 3.51e-01 96.2% 83.9%
5029970 4312.1.1.0 ↗ a+b two layers › RelE-like › RelE-like › RelE-like 0.54 38.0 3.56e-01 86.1% 58.6%
383967 216.1.1.7 ↗ a+b two layers › UBC-like › UBC-like › UBC-like › FANCL_d1 0.54 43.0 4.13e-01 87.3% 98.9%
3585833 330.1.1.1 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › dsrm 0.54 42.0 3.79e-01 84.8% 67.3%
3783932 101.1.9.47 ↗ alpha arrays › HTH › HTH › Putative DNA-binding domain › STE 0.54 47.0 3.82e-01 98.7% 67.7%
4274836 3016.1.1.1 ↗ a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › Aminotran_1_2 0.53 44.0 4.01e-01 94.9% 84.5%
3592294 330.1.1.0 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.53 45.0 3.42e-01 96.2% 56.5%
5074509 241.11.1.7 ↗ a+b two layers › Type III secretory system chaperone-like › YjbR-like › YjbR-like › DUF3788 0.53 45.0 3.85e-01 97.5% 92.6%
3856193 6.1.1.16 ↗ beta duplicates or obligate multimers › beta-Trefoil › beta-Trefoil › beta-Trefoil › BTD 0.53 41.0 3.32e-01 88.6% 76.6%
3472014 1.1.1.1 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › Asp 0.53 39.0 2.65e-01 83.5% 78.4%
3585692 216.1.1.20 ↗ a+b two layers › UBC-like › UBC-like › UBC-like › UBC_like 0.52 43.0 3.60e-01 94.9% 66.7%
4950085 206.1.3.21 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › RimK 0.52 41.0 2.98e-01 91.1% 96.5%
5000550 5.1.4.43 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › FG-GAP_3 0.52 42.0 2.86e-01 92.4% 26.8%
3331262 216.1.1.20 ↗ a+b two layers › UBC-like › UBC-like › UBC-like › UBC_like 0.51 41.0 3.94e-01 92.4% 100.0%
4942367 2008.1.1.0 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.51 37.0 3.50e-01 77.2% 76.8%
3508120 214.1.1.10 ↗ a+b two layers › SH2 › SH2 › SH2 › DUF7145 0.51 42.0 3.78e-01 93.7% 86.1%
3190458 3484.1.1.2 ↗ a+b two layers › Laminaripentaose-producing beta-1,3-glucanase insertion domain › Laminaripentaose-producing beta-1,3-glucanase insertion domain › Laminaripentaose-producing beta-1,3-glucanase insertion domain › Glyco_hydro_64 0.51 39.0 3.09e-01 84.8% 53.7%
3743864 109.4.1.1787 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Nup188_N-subdom_III 0.51 45.0 2.50e-01 100.0% 10.5%
3514663 330.1.1.1 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › dsrm 0.51 40.0 4.12e-01 89.9% 93.3%
3234330 330.1.1.1 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › dsrm 0.51 39.0 3.60e-01 88.6% 61.8%
3506772 214.1.1.10 ↗ a+b two layers › SH2 › SH2 › SH2 › DUF7145 0.51 42.0 3.67e-01 93.7% 77.6%
5042834 274.1.1.0 ↗ a+b two layers › Pili subunits › Pili subunits › Pili subunits 0.50 42.0 3.48e-01 94.9% 65.3%
5027390 206.1.1.9 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › RIO1 0.50 38.0 2.69e-01 83.5% 40.3%
4972588 2004.1.1.293 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_15 0.50 42.0 2.87e-01 96.2% 67.7%
3299579 330.1.1.1 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › dsrm 0.50 36.0 3.77e-01 77.2% 92.9%
D2 high residues 234-333
PDB
D3 high residues 355-380_406-498
PDB
D4 high residues 528-652
PDB
D5 high residues 658-747
PDB
Domain cluster: representative
CATH (35)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
5m9dA00 1.25.40.90 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.75 68.0 5.87e-01 100.0% 80.4%
1gw5B00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.71 60.0 3.66e-01 93.3% 59.8%
6t0bf00 1.25.40.40 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Cytochrome c oxidase, subunit Va/VI 0.70 59.0 5.71e-01 95.6% 91.2%
2vsoF01 1.25.40.180 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.69 62.0 4.62e-01 100.0% 58.9%
2pmvA01 1.50.10.20 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › 0.68 58.0 4.22e-01 95.6% 39.0%
2db0B00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.68 59.0 4.41e-01 98.9% 57.1%
2w3cA02 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.68 57.0 4.08e-01 95.6% 60.5%
4kx7A04 1.25.50.20 Mainly Alpha › Alpha Horseshoe › Zincin-like fold › 0.66 55.0 3.80e-01 93.3% 30.7%
5dlqB01 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.66 56.0 3.65e-01 95.6% 30.3%
1ug3A01 1.25.40.180 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.66 56.0 4.41e-01 95.6% 57.9%
2l1lB00 1.20.1440.250 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.64 55.0 4.94e-01 95.6% 94.5%
1mhyG02 1.20.1280.30 Mainly Alpha › Up-down Bundle › Monooxygenase › Methane monooxygenase, gamma chain, domain 2 0.64 43.0 4.65e-01 94.4% 84.9%
2np5D00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.62 50.0 4.28e-01 91.1% 84.2%
2lhrA00 1.20.58.1270 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.61 40.0 4.21e-01 97.8% 75.6%
4q5rA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.61 42.0 4.01e-01 73.3% 92.0%
1vdyA00 1.25.40.90 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.61 51.0 4.50e-01 96.7% 80.0%
3vbbE01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.60 32.0 2.93e-01 83.3% 37.0%
2l3lA01 1.20.58.1250 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Tubulin Binding Cofactor C, N-terminal domain 0.60 47.0 4.43e-01 96.7% 69.8%
3vprA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.59 40.0 3.52e-01 71.1% 77.2%
1o5hA00 1.20.120.680 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Formiminotetrahydrofolate cyclodeaminase monomer, up-and-down helical bundle 0.59 43.0 3.44e-01 80.0% 56.0%
2r5sA02 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.58 49.0 4.98e-01 96.7% 100.0%
4nqwA02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.58 32.0 3.64e-01 78.9% 73.4%
1v9mA01 1.10.132.50 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › ATP synthase (C/AC39) subunit, domain 3 0.58 37.0 3.45e-01 78.9% 51.3%
2r5sA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.57 47.0 4.91e-01 95.6% 100.0%
2a0bA00 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.57 40.0 3.63e-01 95.6% 55.1%
3bvoA02 1.20.1280.20 Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain 0.57 46.0 4.72e-01 96.7% 89.5%
2ggfA00 1.25.40.180 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.56 48.0 4.30e-01 98.9% 85.4%
3gedA00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.56 44.0 3.27e-01 86.7% 71.1%
3h0dB02 1.10.1200.150 Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › Transcriptional repressor of class III stress genes, C-terminal domain 0.55 37.0 3.88e-01 100.0% 76.5%
7c1iA01 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.54 40.0 3.88e-01 92.2% 68.0%
2e52B01 3.40.91.70 Alpha Beta › 3-Layer(aba) Sandwich › Restriction Endonuclease › Type II restriction endonuclease, HindIII 0.53 46.0 3.48e-01 97.8% 73.2%
3qp1A00 3.30.450.80 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › Transcription factor LuxR-like, autoinducer-binding domain 0.52 47.0 3.70e-01 96.7% 94.9%
2xl4A00 1.20.120.1420 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › LntA helical domain 0.52 41.0 3.50e-01 85.6% 68.0%
3pvuA02 1.10.167.10 Mainly Alpha › Orthogonal Bundle › Regulator of G-protein Signalling 4; domain 2 › Regulator of G-protein Signalling 4, domain 2 0.51 35.0 3.64e-01 92.2% 77.5%
4udsA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.51 42.0 3.41e-01 95.6% 81.6%
ECOD (42)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3662101 611.3.1.0 ↗ alpha bundles › N-cbl like › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 0.81 55.0 5.96e-01 70.0% 97.3%
3647237 611.3.1.0 ↗ alpha bundles › N-cbl like › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 0.77 60.0 5.46e-01 83.3% 82.5%
3377512 109.4.1.1146 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › ARM_PUB 0.76 67.0 4.54e-01 96.7% 33.0%
3467990 109.4.1.1291 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, PPR_3, DYW_deaminase, E_motif 0.76 69.0 4.07e-01 100.0% 14.0%
3217250 109.4.1.934 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HEAT_ATR 0.76 68.0 3.90e-01 100.0% 12.0%
3471968 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.75 65.0 4.59e-01 96.7% 46.3%
3479739 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.75 65.0 3.84e-01 96.7% 18.2%
3429997 611.3.1.0 ↗ alpha bundles › N-cbl like › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 0.74 60.0 5.75e-01 88.9% 87.6%
3608296 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.73 57.0 5.40e-01 83.3% 92.4%
3310873 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.72 63.0 5.14e-01 95.6% 66.7%
3682692 611.3.1.0 ↗ alpha bundles › N-cbl like › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 0.72 63.0 4.72e-01 95.6% 51.6%
3742462 109.4.1.441 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TFCD_C 0.71 63.0 5.05e-01 100.0% 58.9%
3171905 109.4.1.22 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Adaptin_N 0.71 62.0 4.67e-01 96.7% 44.5%
3840929 109.27.1.1 ↗ alpha superhelices › Repetitive alpha hairpins › BACK domain › BACK domain › BACK 0.71 64.0 5.52e-01 100.0% 65.7%
3172093 604.1.1.132 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › KAR9 0.71 50.0 4.47e-01 73.3% 84.8%
4028757 109.4.1.2082 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF26172 0.70 60.0 4.15e-01 95.6% 29.7%
3576811 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.70 63.0 4.54e-01 100.0% 36.5%
3320567 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.70 62.0 4.61e-01 100.0% 62.9%
3370733 109.4.1.1295 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, PPR_3, TPR_24 0.70 62.0 3.91e-01 100.0% 19.2%
3214973 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.69 61.0 4.07e-01 100.0% 69.3%
3593885 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.69 60.0 4.00e-01 100.0% 29.7%
3317626 109.4.1.285 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PSMD12-CSN4_N 0.69 60.0 4.27e-01 100.0% 36.6%
3831524 109.4.1.1275 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_1, PPR_2, PPR_3, PPR_long, TPR_24 0.68 59.0 3.53e-01 100.0% 13.3%
3425658 109.4.1.1271 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, TPR_24 0.68 60.0 4.44e-01 100.0% 38.7%
3561044 176.1.1.2 ↗ alpha arrays › Annexin › Annexin › Annexin › Annexin_2 0.68 51.0 5.14e-01 80.0% 88.9%
3442398 109.4.1.420 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR 0.67 59.0 4.92e-01 100.0% 73.3%
3462135 109.4.1.16 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PUF 0.67 60.0 3.93e-01 100.0% 25.6%
3603424 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.67 57.0 4.45e-01 96.7% 66.3%
3302418 109.27.1.3 ↗ alpha superhelices › Repetitive alpha hairpins › BACK domain › BACK domain › NPH3 0.66 54.0 5.56e-01 87.8% 98.8%
3263316 109.4.1.661 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › CNOT11 0.66 57.0 4.68e-01 100.0% 56.0%
4958889 1075.1.1.0 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain 0.65 48.0 3.69e-01 78.9% 51.4%
3649549 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.65 54.0 5.11e-01 92.2% 75.5%
3421799 109.27.1.3 ↗ alpha superhelices › Repetitive alpha hairpins › BACK domain › BACK domain › NPH3 0.64 55.0 5.04e-01 92.2% 76.5%
3717647 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.64 50.0 3.44e-01 85.6% 44.5%
3418273 109.4.1.240 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR_long 0.63 55.0 3.93e-01 100.0% 33.0%
3188275 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.62 47.0 3.82e-01 82.2% 95.6%
3825574 109.4.1.1157 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_WDR11 0.60 50.0 3.77e-01 100.0% 37.3%
3336387 109.27.1.1 ↗ alpha superhelices › Repetitive alpha hairpins › BACK domain › BACK domain › BACK 0.60 52.0 4.33e-01 100.0% 55.0%
4932195 4995.1.1.1 ↗ alpha arrays › Methionine synthase domain-like › Methionine synthase domain-like › Methionine synthase domain-like › B12-binding_2 0.58 41.0 3.79e-01 73.3% 70.8%
3590111 7516.1.1.2 ↗ a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2 0.58 48.0 3.36e-01 96.7% 52.9%
3307491 109.54.1.1 ↗ alpha superhelices › Repetitive alpha hairpins › C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 › C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 › Utp12 0.55 44.0 3.78e-01 91.1% 60.0%
3440159 130.1.1.0 ↗ alpha arrays › LEM/SAP HeH motif-like › LEM/SAP HeH motif › LEM/SAP HeH motif 0.53 39.0 4.08e-01 91.1% 82.4%
D6 medium residues 10-72
PDB
Domain cluster: representative
CATH (24)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
6my0A02 2.30.30.30 Mainly Beta › Roll › SH3 type barrels. › 0.79 36.0 3.63e-01 77.8% 41.5%
6fndA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.64 36.0 2.57e-01 84.1% 18.8%
2dx0A00 3.30.505.10 Alpha Beta › 2-Layer Sandwich › SHC Adaptor Protein › SH2 domain 0.63 49.0 4.07e-01 87.3% 88.0%
6i18A04 2.80.10.50 Mainly Beta › Trefoil › Trefoil (Acidic Fibroblast Growth Factor, subunit A) › 0.60 42.0 3.64e-01 76.2% 87.9%
3sluA02 3.10.450.350 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.60 45.0 3.63e-01 85.7% 71.5%
6ptrB01 3.10.150.10 Alpha Beta › Roll › DNA Polymerase III; Chain A, domain 2 › DNA Polymerase III, subunit A, domain 2 0.59 45.0 3.78e-01 84.1% 92.9%
5xrwC00 2.30.330.10 Mainly Beta › Roll › Surface presentation of antigens (SPOA) › SpoA-like 0.59 34.0 3.25e-01 100.0% 46.2%
2uz8A01 3.40.30.90 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › 0.58 44.0 4.58e-01 84.1% 100.0%
3qwuA02 3.30.470.30 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme 0.58 46.0 3.39e-01 90.5% 55.6%
3mazA00 3.30.505.10 Alpha Beta › 2-Layer Sandwich › SHC Adaptor Protein › SH2 domain 0.57 42.0 3.73e-01 82.5% 89.9%
2fiaB00 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.56 44.0 3.38e-01 88.9% 71.1%
1hf2A02 2.160.20.70 Mainly Beta › 3 Solenoid › Pectate Lyase C-like › 0.56 38.0 3.26e-01 79.4% 43.4%
2hqvA00 3.40.1570.10 Alpha Beta › 3-Layer(aba) Sandwich › Heme iron utilization protein-like fold › HemS/ChuS/ChuX like domains 0.55 41.0 3.13e-01 84.1% 54.1%
2jhnA01 3.30.310.20 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › DNA-3-methyladenine glycosylase AlkA, N-terminal domain 0.55 33.0 2.81e-01 87.3% 33.6%
3k1lA01 3.30.457.40 Alpha Beta › 2-Layer Sandwich › Copper Amine Oxidase; Chain A, domain 1 › 0.55 41.0 3.70e-01 84.1% 95.7%
3rmhB00 2.40.50.810 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › 0.54 46.0 3.72e-01 100.0% 87.2%
3zx7A02 2.80.10.50 Mainly Beta › Trefoil › Trefoil (Acidic Fibroblast Growth Factor, subunit A) › 0.54 44.0 3.47e-01 92.1% 83.2%
3gdoA02 3.30.360.10 Alpha Beta › 2-Layer Sandwich › Dihydrodipicolinate Reductase; domain 2 › Dihydrodipicolinate Reductase; domain 2 0.54 39.0 2.86e-01 81.0% 34.2%
3fhlA02 3.30.360.10 Alpha Beta › 2-Layer Sandwich › Dihydrodipicolinate Reductase; domain 2 › Dihydrodipicolinate Reductase; domain 2 0.53 39.0 2.91e-01 81.0% 39.1%
1ckeA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.53 41.0 2.89e-01 85.7% 30.7%
4yapA01 3.40.30.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin 0.53 43.0 3.58e-01 96.8% 60.3%
2dx0B01 3.30.505.10 Alpha Beta › 2-Layer Sandwich › SHC Adaptor Protein › SH2 domain 0.52 40.0 3.86e-01 85.7% 72.0%
2gtjA01 2.30.30.40 Mainly Beta › Roll › SH3 type barrels. › SH3 Domains 0.52 38.0 3.65e-01 84.1% 66.2%
4hz2A01 3.40.30.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin 0.50 40.0 3.81e-01 98.4% 92.6%
ECOD (26)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3213123 4.1.1.0 ↗ beta barrels › SH3 › SH3 › SH3 0.80 40.0 5.21e-01 81.0% 100.0%
3933654 386.1.1.0 ↗ few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers 0.71 46.0 5.22e-01 95.2% 93.3%
3927790 386.1.1.0 ↗ few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers 0.66 45.0 5.04e-01 100.0% 100.0%
3700743 327.11.2.0 ↗ a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) 0.66 33.0 3.21e-01 92.1% 40.0%
3213942 214.1.1.1 ↗ a+b two layers › SH2 › SH2 › SH2 › SH2 0.66 50.0 4.24e-01 84.1% 95.5%
3542444 214.1.1.1 ↗ a+b two layers › SH2 › SH2 › SH2 › SH2 0.64 48.0 3.73e-01 84.1% 65.8%
3766764 214.1.1.0 ↗ a+b two layers › SH2 › SH2 › SH2 0.63 48.0 3.16e-01 84.1% 35.1%
3236787 2484.1.1.200 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › FTH 0.63 34.0 2.72e-01 82.5% 23.8%
3801304 214.1.1.1 ↗ a+b two layers › SH2 › SH2 › SH2 › SH2 0.62 49.0 3.87e-01 88.9% 75.7%
3838045 375.1.1.0 ↗ few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.62 35.0 4.26e-01 82.5% 100.0%
5052895 375.1.1.0 ↗ few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.61 32.0 3.43e-01 73.0% 58.2%
3390566 330.1.1.0 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.59 41.0 3.62e-01 73.0% 65.0%
3799710 2.6.1.0 ↗ beta barrels › OB-fold › Staphylococcal nuclease › Staphylococcal nuclease 0.59 47.0 4.36e-01 93.7% 92.9%
3844043 252.1.1.1 ↗ a+b two layers › DNA-binding domain › Methyl-CpG-binding domain, MBD › Methyl-CpG-binding domain, MBD › MBD 0.58 35.0 3.59e-01 98.4% 61.7%
3514663 330.1.1.1 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › dsrm 0.57 40.0 3.90e-01 77.8% 93.3%
4934815 3124.1.1.0 ↗ beta sandwiches › Nascent polypeptide-associated complex (NAC) dimerization domain › Nascent polypeptide-associated complex (NAC) dimerization domain › Nascent polypeptide-associated complex (NAC) dimerization domain 0.57 37.0 4.22e-01 92.1% 93.3%
3585826 375.1.1.0 ↗ few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.57 35.0 4.23e-01 73.0% 100.0%
None — 0.57 44.0 2.96e-01 88.9% 59.3%
4929446 316.1.1.0 ↗ a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase 0.56 40.0 2.99e-01 74.6% 42.6%
2543709 2003.1.2.60 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › DAO, NAD_binding_8 0.56 42.0 2.87e-01 81.0% 87.7%
4975877 2487.1.1.0 ↗ a/b three-layered sandwiches › "The ""swivelling"" beta/beta/alpha domains" › "The ""swivelling"" beta/beta/alpha domain" › "The ""swivelling"" beta/beta/alpha domain" 0.54 43.0 3.31e-01 88.9% 76.8%
3946113 241.7.1.1 ↗ a+b two layers › Type III secretory system chaperone-like › YgaC/TfoX-N like › YgaC/TfoX-N like › TfoX_N 0.54 39.0 3.45e-01 82.5% 94.3%
5012906 2498.2.1.6 ↗ mixed a+b and a/b › Zincin-like › beta-N-acetylhexosaminidase-like domain › beta-N-acetylhexosaminidase-like domain › S_layer_C 0.52 41.0 2.99e-01 95.2% 68.6%
1501287 601.52.1.2 ↗ alpha bundles › Four-helical up-and-down bundle › Flagellar hook-associated protein 1 helical domain › Flagellar hook-associated protein 1 helical domain › FlgK_D1 0.51 44.0 2.98e-01 100.0% 76.4%
3723645 298.1.1.24 ↗ a+b two layers › FwdE/GAPDH domain-like › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain › GFO_IDH_MocA_C3 0.50 39.0 2.78e-01 87.3% 36.3%
3482923 708.1.1.0 ↗ beta complex topology › ETN0001 domain-like › ETN0001 domain-like › NAC/WRKY/GCM/WOPR domain 0.50 38.0 3.37e-01 84.1% 93.7%