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Serine_Threonine_protein_phosphatase
Euk-VirAcanthamoeba_polyphaga_moumouvirus
Serine_Threonine_protein_phosphatase__YP_007354495__Acanthamoeba_polyphaga_moumouvirus__1269028
Identity
- Accession:
- YP_007354495 ↗
- Protein ID:
- Serine_Threonine_protein_phosphatase
- Kingdom:
- euk
Quality
72.1
mean pLDDT
Taxonomy
Bamfordvirae›
Nucleocytoviricota›
Megaviricetes›
Imitervirales›
Mimiviridae›
Moumouvirus›
Acanthamoeba_polyphaga_moumouvirus
TaxID: 1269028
Cluster
View cluster (22 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 26-161_202-227
Domain cluster:
rep: putative_family_2C_serine_threonine_phosphatase__YP_003970108__Cafeteria_roenbergensis_virus_BV-PW1__693272__D17-131_185-209
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00481.27 best | PP2C | 56.7 | 4.30e-15 | 85.2% | 51.8% |
CATH (11)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2iq1A00 | 3.60.40.10 | Alpha Beta › 4-Layer Sandwich › Phosphatase 2c; domain 1 › PPM-type phosphatase domain | 0.65 | 62.0 | 5.22e-01 | 100.0% | 72.8% |
| 2j82A00 | 3.60.40.10 | Alpha Beta › 4-Layer Sandwich › Phosphatase 2c; domain 1 › PPM-type phosphatase domain | 0.62 | 58.0 | 5.12e-01 | 100.0% | 71.9% |
| 2jfrA00 | 3.60.40.10 | Alpha Beta › 4-Layer Sandwich › Phosphatase 2c; domain 1 › PPM-type phosphatase domain | 0.59 | 56.0 | 4.84e-01 | 100.0% | 70.9% |
| 1txoB00 | 3.60.40.10 | Alpha Beta › 4-Layer Sandwich › Phosphatase 2c; domain 1 › PPM-type phosphatase domain | 0.58 | 55.0 | 4.81e-01 | 100.0% | 71.6% |
| 3g7gH00 | 2.40.160.20 | Mainly Beta › Beta Barrel › Porin › | 0.58 | 36.0 | 3.79e-01 | 98.8% | 65.8% |
| 2vf9A00 | 3.30.380.10 | Alpha Beta › 2-Layer Sandwich › MS2 Viral Coat Protein › MS2 Viral Coat Protein | 0.58 | 34.0 | 3.81e-01 | 100.0% | 72.5% |
| 1aq3A00 | 3.30.380.10 | Alpha Beta › 2-Layer Sandwich › MS2 Viral Coat Protein › MS2 Viral Coat Protein | 0.57 | 34.0 | 3.82e-01 | 100.0% | 73.6% |
| 4nzjA03 | 2.60.40.1180 | Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II | 0.55 | 30.0 | 3.99e-01 | 83.3% | 97.7% |
| 4ca1B02 | 2.60.210.10 | Mainly Beta › Sandwich › Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A › Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A | 0.51 | 34.0 | 3.75e-01 | 94.4% | 82.6% |
| 5azpA02 | 2.20.200.10 | Mainly Beta › Single Sheet › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) | 0.50 | 25.0 | 3.30e-01 | 84.6% | 90.1% |
| 1o0vA03 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.50 | 32.0 | 3.70e-01 | 92.0% | 92.7% |
ECOD (25)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3816781 | 210.2.1.1 ↗ | a+b four layers › Ntn/PP2C › Protein serine/threonine phosphatase 2C, catalytic domain › Protein serine/threonine phosphatase 2C, catalytic domain › PP2C | 0.79 | 59.0 | 5.31e-01 | 94.4% | 58.1% |
| 3414586 | 11.1.1.824 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Chitin_bind_4 | 0.77 | 32.0 | 4.17e-01 | 92.6% | 67.7% |
| 3601494 | 210.2.1.0 ↗ | a+b four layers › Ntn/PP2C › Protein serine/threonine phosphatase 2C, catalytic domain › Protein serine/threonine phosphatase 2C, catalytic domain | 0.69 | 66.0 | 5.16e-01 | 100.0% | 69.8% |
| 3759773 | 210.2.1.1 ↗ | a+b four layers › Ntn/PP2C › Protein serine/threonine phosphatase 2C, catalytic domain › Protein serine/threonine phosphatase 2C, catalytic domain › PP2C | 0.68 | 65.0 | 5.35e-01 | 100.0% | 70.4% |
| 3266570 | 210.2.1.1 ↗ | a+b four layers › Ntn/PP2C › Protein serine/threonine phosphatase 2C, catalytic domain › Protein serine/threonine phosphatase 2C, catalytic domain › PP2C | 0.67 | 64.0 | 5.17e-01 | 100.0% | 71.7% |
| 3300599 | 210.2.1.1 ↗ | a+b four layers › Ntn/PP2C › Protein serine/threonine phosphatase 2C, catalytic domain › Protein serine/threonine phosphatase 2C, catalytic domain › PP2C | 0.67 | 64.0 | 4.94e-01 | 100.0% | 69.5% |
| 3318487 | 210.2.1.1 ↗ | a+b four layers › Ntn/PP2C › Protein serine/threonine phosphatase 2C, catalytic domain › Protein serine/threonine phosphatase 2C, catalytic domain › PP2C | 0.67 | 63.0 | 5.12e-01 | 100.0% | 70.9% |
| 3673438 | 210.2.1.1 ↗ | a+b four layers › Ntn/PP2C › Protein serine/threonine phosphatase 2C, catalytic domain › Protein serine/threonine phosphatase 2C, catalytic domain › PP2C | 0.67 | 63.0 | 4.97e-01 | 100.0% | 74.5% |
| 3820823 | 210.2.1.1 ↗ | a+b four layers › Ntn/PP2C › Protein serine/threonine phosphatase 2C, catalytic domain › Protein serine/threonine phosphatase 2C, catalytic domain › PP2C | 0.67 | 64.0 | 5.31e-01 | 100.0% | 71.4% |
| 3812041 | 12.1.1.36 ↗ | beta sandwiches › Glycosyl hydrolase domain-like › Glycosyl hydrolase domain › Glycosyl hydrolase domain › GHD | 0.66 | 27.0 | 3.59e-01 | 83.3% | 67.8% |
| 3502363 | 210.2.1.1 ↗ | a+b four layers › Ntn/PP2C › Protein serine/threonine phosphatase 2C, catalytic domain › Protein serine/threonine phosphatase 2C, catalytic domain › PP2C | 0.66 | 62.0 | 5.18e-01 | 100.0% | 71.3% |
| 3551370 | 210.2.1.1 ↗ | a+b four layers › Ntn/PP2C › Protein serine/threonine phosphatase 2C, catalytic domain › Protein serine/threonine phosphatase 2C, catalytic domain › PP2C | 0.65 | 63.0 | 5.10e-01 | 100.0% | 69.1% |
| 3957775 | 210.2.1.2 ↗ | a+b four layers › Ntn/PP2C › Protein serine/threonine phosphatase 2C, catalytic domain › Protein serine/threonine phosphatase 2C, catalytic domain › SpoIIE | 0.63 | 55.0 | 4.81e-01 | 100.0% | 63.9% |
| 4240462 | 210.2.1.0 ↗ | a+b four layers › Ntn/PP2C › Protein serine/threonine phosphatase 2C, catalytic domain › Protein serine/threonine phosphatase 2C, catalytic domain | 0.63 | 59.0 | 4.42e-01 | 100.0% | 49.5% |
| 3687439 | 12.6.1.3 ↗ | beta sandwiches › Glycosyl hydrolase domain-like › Glycoside hydrolase family 127 middle domain-related › Glycoside hydrolase family 127 middle domain-related › Bac_rhamnosid_C | 0.63 | 29.0 | 4.23e-01 | 84.0% | 97.3% |
| 3594605 | 210.2.1.0 ↗ | a+b four layers › Ntn/PP2C › Protein serine/threonine phosphatase 2C, catalytic domain › Protein serine/threonine phosphatase 2C, catalytic domain | 0.62 | 58.0 | 4.55e-01 | 100.0% | 68.6% |
| 3605951 | 210.2.1.2 ↗ | a+b four layers › Ntn/PP2C › Protein serine/threonine phosphatase 2C, catalytic domain › Protein serine/threonine phosphatase 2C, catalytic domain › SpoIIE | 0.62 | 58.0 | 4.50e-01 | 100.0% | 58.8% |
| 3281496 | 210.2.1.3 ↗ | a+b four layers › Ntn/PP2C › Protein serine/threonine phosphatase 2C, catalytic domain › Protein serine/threonine phosphatase 2C, catalytic domain › PP2C_2 | 0.61 | 58.0 | 4.97e-01 | 100.0% | 72.7% |
| 164998 | 210.2.1.3 ↗ | a+b four layers › Ntn/PP2C › Protein serine/threonine phosphatase 2C, catalytic domain › Protein serine/threonine phosphatase 2C, catalytic domain › PP2C_2 | 0.59 | 56.0 | 4.84e-01 | 100.0% | 70.9% |
| 169039 | 265.1.1.1 ↗ | a+b two layers › RNA bacteriophage capsid protein › RNA bacteriophage capsid protein › RNA bacteriophage capsid protein › Levi_coat | 0.58 | 34.0 | 3.81e-01 | 100.0% | 72.5% |
| 3276063 | 210.1.4.1 ↗ | a+b four layers › Ntn/PP2C › Ntn › (Glycosyl)asparaginase › Asparaginase_2 | 0.57 | 52.0 | 3.91e-01 | 99.4% | 75.4% |
| 3741673 | 210.1.4.1 ↗ | a+b four layers › Ntn/PP2C › Ntn › (Glycosyl)asparaginase › Asparaginase_2 | 0.56 | 51.0 | 3.98e-01 | 98.1% | 77.7% |
| 3999353 | 210.1.4.1 ↗ | a+b four layers › Ntn/PP2C › Ntn › (Glycosyl)asparaginase › Asparaginase_2 | 0.53 | 48.0 | 3.80e-01 | 98.1% | 88.3% |
| 4966094 | 11.1.1.1428 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › DUF7846 | 0.52 | 33.0 | 3.14e-01 | 83.3% | 51.5% |
| 4015605 | 3385.1.1.0 ↗ | beta barrels › Allergen Alt a 1 › Allergen Alt a 1 › Allergen Alt a 1 | 0.50 | 37.0 | 3.60e-01 | 75.3% | 92.6% |
D2
medium
residues 166-199
D3
medium
residues 228-306
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00481.27 best | PP2C | 51.1 | 2.20e-13 | 88.6% | 21.2% |
CATH (11)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2p8eA00 | 3.60.40.10 | Alpha Beta › 4-Layer Sandwich › Phosphatase 2c; domain 1 › PPM-type phosphatase domain | 0.91 | 68.0 | 4.44e-01 | 97.5% | 21.9% |
| 4yzgA00 | 3.60.40.10 | Alpha Beta › 4-Layer Sandwich › Phosphatase 2c; domain 1 › PPM-type phosphatase domain | 0.90 | 69.0 | 4.46e-01 | 100.0% | 21.4% |
| 2iq1A00 | 3.60.40.10 | Alpha Beta › 4-Layer Sandwich › Phosphatase 2c; domain 1 › PPM-type phosphatase domain | 0.88 | 64.0 | 4.28e-01 | 100.0% | 23.0% |
| 2pnqA00 | 3.60.40.10 | Alpha Beta › 4-Layer Sandwich › Phosphatase 2c; domain 1 › PPM-type phosphatase domain | 0.88 | 67.0 | 4.16e-01 | 100.0% | 16.5% |
| 2i44B00 | 3.60.40.10 | Alpha Beta › 4-Layer Sandwich › Phosphatase 2c; domain 1 › PPM-type phosphatase domain | 0.85 | 66.0 | 4.21e-01 | 98.7% | 20.3% |
| 4jndA02 | 3.60.40.10 | Alpha Beta › 4-Layer Sandwich › Phosphatase 2c; domain 1 › PPM-type phosphatase domain | 0.85 | 67.0 | 4.40e-01 | 100.0% | 23.4% |
| 2pk0A00 | 3.60.40.10 | Alpha Beta › 4-Layer Sandwich › Phosphatase 2c; domain 1 › PPM-type phosphatase domain | 0.84 | 63.0 | 4.26e-01 | 100.0% | 24.7% |
| 3jrqA00 | 3.60.40.10 | Alpha Beta › 4-Layer Sandwich › Phosphatase 2c; domain 1 › PPM-type phosphatase domain | 0.82 | 65.0 | 4.32e-01 | 98.7% | 24.0% |
| 2j82A00 | 3.60.40.10 | Alpha Beta › 4-Layer Sandwich › Phosphatase 2c; domain 1 › PPM-type phosphatase domain | 0.64 | 59.0 | 4.12e-01 | 97.5% | 44.8% |
| 1d2iA00 | 3.40.91.20 | Alpha Beta › 3-Layer(aba) Sandwich › Restriction Endonuclease › | 0.54 | 45.0 | 3.39e-01 | 98.7% | 79.7% |
| 1mswD01 | 1.10.1320.10 | Mainly Alpha › Orthogonal Bundle › T7 RNA polymerase; domain 1 › DNA-directed RNA polymerase, N-terminal domain | 0.51 | 45.0 | 3.04e-01 | 98.7% | 52.9% |
ECOD (28)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3803591 | 210.2.1.1 ↗ | a+b four layers › Ntn/PP2C › Protein serine/threonine phosphatase 2C, catalytic domain › Protein serine/threonine phosphatase 2C, catalytic domain › PP2C | 0.91 | 67.0 | 4.30e-01 | 100.0% | 19.8% |
| 3790561 | 210.2.1.1 ↗ | a+b four layers › Ntn/PP2C › Protein serine/threonine phosphatase 2C, catalytic domain › Protein serine/threonine phosphatase 2C, catalytic domain › PP2C | 0.90 | 70.0 | 4.55e-01 | 98.7% | 22.6% |
| 4024082 | 210.2.1.1 ↗ | a+b four layers › Ntn/PP2C › Protein serine/threonine phosphatase 2C, catalytic domain › Protein serine/threonine phosphatase 2C, catalytic domain › PP2C | 0.89 | 63.0 | 4.03e-01 | 97.5% | 18.2% |
| 3743422 | 210.2.1.1 ↗ | a+b four layers › Ntn/PP2C › Protein serine/threonine phosphatase 2C, catalytic domain › Protein serine/threonine phosphatase 2C, catalytic domain › PP2C | 0.85 | 64.0 | 4.22e-01 | 100.0% | 22.1% |
| 3266570 | 210.2.1.1 ↗ | a+b four layers › Ntn/PP2C › Protein serine/threonine phosphatase 2C, catalytic domain › Protein serine/threonine phosphatase 2C, catalytic domain › PP2C | 0.82 | 71.0 | 4.58e-01 | 100.0% | 24.5% |
| 3244904 | 210.2.1.1 ↗ | a+b four layers › Ntn/PP2C › Protein serine/threonine phosphatase 2C, catalytic domain › Protein serine/threonine phosphatase 2C, catalytic domain › PP2C | 0.82 | 59.0 | 4.21e-01 | 100.0% | 28.1% |
| 3816781 | 210.2.1.1 ↗ | a+b four layers › Ntn/PP2C › Protein serine/threonine phosphatase 2C, catalytic domain › Protein serine/threonine phosphatase 2C, catalytic domain › PP2C | 0.81 | 64.0 | 4.50e-01 | 100.0% | 30.2% |
| 3599175 | 210.2.1.0 ↗ | a+b four layers › Ntn/PP2C › Protein serine/threonine phosphatase 2C, catalytic domain › Protein serine/threonine phosphatase 2C, catalytic domain | 0.81 | 66.0 | 4.27e-01 | 100.0% | 22.7% |
| 3170065 | 210.2.1.1 ↗ | a+b four layers › Ntn/PP2C › Protein serine/threonine phosphatase 2C, catalytic domain › Protein serine/threonine phosphatase 2C, catalytic domain › PP2C | 0.79 | 66.0 | 4.09e-01 | 100.0% | 17.8% |
| 3193127 | 210.2.1.1 ↗ | a+b four layers › Ntn/PP2C › Protein serine/threonine phosphatase 2C, catalytic domain › Protein serine/threonine phosphatase 2C, catalytic domain › PP2C | 0.75 | 70.0 | 4.32e-01 | 100.0% | 53.3% |
| 4024026 | 210.2.1.1 ↗ | a+b four layers › Ntn/PP2C › Protein serine/threonine phosphatase 2C, catalytic domain › Protein serine/threonine phosphatase 2C, catalytic domain › PP2C | 0.73 | 67.0 | 4.37e-01 | 100.0% | 25.9% |
| 3223606 | 210.2.1.1 ↗ | a+b four layers › Ntn/PP2C › Protein serine/threonine phosphatase 2C, catalytic domain › Protein serine/threonine phosphatase 2C, catalytic domain › PP2C | 0.72 | 68.0 | 4.43e-01 | 100.0% | 26.4% |
| 3336917 | 210.2.1.1 ↗ | a+b four layers › Ntn/PP2C › Protein serine/threonine phosphatase 2C, catalytic domain › Protein serine/threonine phosphatase 2C, catalytic domain › PP2C | 0.72 | 68.0 | 4.21e-01 | 100.0% | 22.0% |
| 3923062 | 210.2.1.1 ↗ | a+b four layers › Ntn/PP2C › Protein serine/threonine phosphatase 2C, catalytic domain › Protein serine/threonine phosphatase 2C, catalytic domain › PP2C | 0.71 | 63.0 | 3.91e-01 | 100.0% | 19.2% |
| 3679942 | 210.2.1.1 ↗ | a+b four layers › Ntn/PP2C › Protein serine/threonine phosphatase 2C, catalytic domain › Protein serine/threonine phosphatase 2C, catalytic domain › PP2C | 0.71 | 68.0 | 4.27e-01 | 100.0% | 24.5% |
| 3673438 | 210.2.1.1 ↗ | a+b four layers › Ntn/PP2C › Protein serine/threonine phosphatase 2C, catalytic domain › Protein serine/threonine phosphatase 2C, catalytic domain › PP2C | 0.71 | 67.0 | 4.32e-01 | 100.0% | 50.0% |
| 3666534 | 210.2.1.1 ↗ | a+b four layers › Ntn/PP2C › Protein serine/threonine phosphatase 2C, catalytic domain › Protein serine/threonine phosphatase 2C, catalytic domain › PP2C | 0.69 | 66.0 | 4.12e-01 | 100.0% | 23.0% |
| 3652660 | 210.2.1.1 ↗ | a+b four layers › Ntn/PP2C › Protein serine/threonine phosphatase 2C, catalytic domain › Protein serine/threonine phosphatase 2C, catalytic domain › PP2C | 0.69 | 66.0 | 4.47e-01 | 100.0% | 32.7% |
| 3789422 | 210.2.1.3 ↗ | a+b four layers › Ntn/PP2C › Protein serine/threonine phosphatase 2C, catalytic domain › Protein serine/threonine phosphatase 2C, catalytic domain › PP2C_2 | 0.67 | 63.0 | 4.14e-01 | 100.0% | 50.0% |
| 4026331 | 210.2.1.1 ↗ | a+b four layers › Ntn/PP2C › Protein serine/threonine phosphatase 2C, catalytic domain › Protein serine/threonine phosphatase 2C, catalytic domain › PP2C | 0.67 | 63.0 | 3.92e-01 | 98.7% | 22.0% |
| 3972243 | 210.2.1.0 ↗ | a+b four layers › Ntn/PP2C › Protein serine/threonine phosphatase 2C, catalytic domain › Protein serine/threonine phosphatase 2C, catalytic domain | 0.65 | 60.0 | 4.28e-01 | 98.7% | 49.8% |
| 4973639 | 210.2.1.3 ↗ | a+b four layers › Ntn/PP2C › Protein serine/threonine phosphatase 2C, catalytic domain › Protein serine/threonine phosphatase 2C, catalytic domain › PP2C_2 | 0.64 | 59.0 | 4.47e-01 | 98.7% | 67.8% |
| 3700328 | 210.2.1.0 ↗ | a+b four layers › Ntn/PP2C › Protein serine/threonine phosphatase 2C, catalytic domain › Protein serine/threonine phosphatase 2C, catalytic domain | 0.63 | 58.0 | 3.93e-01 | 100.0% | 46.4% |
| 3224902 | 197.1.1.0 ↗ | alpha bundles › Acyl-CoA binding protein-like › Acyl-CoA binding protein-like › Acyl-CoA binding protein-like | 0.55 | 38.0 | 4.12e-01 | 72.2% | 96.9% |
| 4996207 | 217.1.1.2 ↗ | a+b complex topology › FAD-binding domain-like › FAD-binding domain › FAD-binding domain › FAD_binding_4 | 0.53 | 39.0 | 2.83e-01 | 81.0% | 86.7% |
| 3345725 | 210.2.1.1 ↗ | a+b four layers › Ntn/PP2C › Protein serine/threonine phosphatase 2C, catalytic domain › Protein serine/threonine phosphatase 2C, catalytic domain › PP2C | 0.52 | 45.0 | 3.15e-01 | 100.0% | 31.9% |
| 3378059 | 10.12.1.10 ↗ | beta sandwiches › jelly-roll › Double-stranded beta-helix › Double-stranded beta-helix › JmjC,JmjN | 0.50 | 39.0 | 2.60e-01 | 86.1% | 87.0% |
| 5007807 | 304.26.1.1 ↗ | a+b two layers › Alpha-beta plaits › MTH1187/YkoF-like › MTH1187/YkoF-like › Thiamine_BP | 0.50 | 44.0 | 4.14e-01 | 98.7% | 87.4% |