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TGF-beta-like_protein

Euk-Vir

Turkeypox_virus

TGF-beta-like_protein__YP_009177082__Turkeypox_virus__336486

Identity

Accession:
YP_009177082 ↗
Protein ID:
TGF-beta-like_protein
Kingdom:
euk

Quality

63.2 mean pLDDT

Cluster

View cluster (3 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 56-179
PDB
Domain cluster: representative
CATH (91)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
5vqfD01 2.60.120.970 Mainly Beta › Sandwich › Jelly Rolls › 0.76 70.0 5.68e-01 100.0% 70.8%
5zruA01 2.60.120.260 Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like 0.70 58.0 5.38e-01 89.5% 100.0%
5z06A01 2.60.120.430 Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding lectin 0.67 55.0 4.90e-01 87.1% 100.0%
3no8A00 2.60.120.820 Mainly Beta › Sandwich › Jelly Rolls › PHR domain 0.67 57.0 5.31e-01 91.9% 99.4%
3wnoA01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.67 46.0 5.09e-01 87.1% 88.0%
4h3wA02 2.60.120.1260 Mainly Beta › Sandwich › Jelly Rolls › 0.65 55.0 5.17e-01 91.9% 90.8%
2wz8A00 2.60.120.260 Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like 0.64 55.0 5.35e-01 91.9% 100.0%
3ks7A01 2.60.120.1570 Mainly Beta › Sandwich › Jelly Rolls › Peptide-N-glycosidase F, N-terminal domain 0.64 53.0 4.50e-01 91.1% 92.9%
7t7zA01 2.60.120.430 Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding lectin 0.64 52.0 4.93e-01 87.1% 100.0%
3eb7A02 2.60.120.260 Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like 0.64 55.0 5.03e-01 94.4% 99.4%
2q1fA01 2.60.120.430 Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding lectin 0.63 53.0 4.79e-01 89.5% 90.4%
1ca1A02 2.60.60.20 Mainly Beta › Sandwich › Lipoxygenase-1 › PLAT/LH2 domain 0.63 46.0 4.69e-01 75.0% 82.5%
7y8sA02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.63 41.0 4.61e-01 88.7% 86.3%
2a74A05 2.60.40.1930 Mainly Beta › Sandwich › Immunoglobulin-like › Macroglobulin (MG2) domain 0.62 46.0 4.91e-01 87.1% 89.5%
4p02B01 2.60.120.260 Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like 0.62 52.0 5.14e-01 91.9% 99.2%
1bu8A02 2.60.60.20 Mainly Beta › Sandwich › Lipoxygenase-1 › PLAT/LH2 domain 0.62 42.0 4.51e-01 70.2% 80.2%
3v0dA02 2.60.40.1110 Mainly Beta › Sandwich › Immunoglobulin-like › 0.62 47.0 4.46e-01 78.2% 97.2%
6r3mA01 2.60.120.430 Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding lectin 0.62 52.0 4.73e-01 91.9% 98.2%
3w57A00 2.60.40.150 Mainly Beta › Sandwich › Immunoglobulin-like › C2 domain 0.62 43.0 4.56e-01 71.8% 93.7%
2h41A00 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.62 41.0 4.62e-01 88.7% 88.4%
4nreA01 2.60.60.20 Mainly Beta › Sandwich › Lipoxygenase-1 › PLAT/LH2 domain 0.62 42.0 4.34e-01 70.2% 80.8%
3w6wB02 2.60.310.20 Mainly Beta › Sandwich › Hemocyanin; Chain: A, domain 2 › 0.62 44.0 4.28e-01 73.4% 78.7%
3cu7A05 2.60.40.1930 Mainly Beta › Sandwich › Immunoglobulin-like › Macroglobulin (MG2) domain 0.62 45.0 4.79e-01 87.1% 87.7%
2v72A00 2.60.120.260 Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like 0.62 52.0 5.03e-01 90.3% 100.0%
3l5iA02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.61 37.0 4.28e-01 90.3% 84.1%
1owwA00 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.61 40.0 4.59e-01 90.3% 89.2%
1va9A00 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.61 42.0 4.32e-01 91.9% 72.1%
2l0dA00 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.61 47.0 4.86e-01 79.8% 86.8%
3v98B01 2.60.60.20 Mainly Beta › Sandwich › Lipoxygenase-1 › PLAT/LH2 domain 0.61 44.0 4.60e-01 98.4% 80.3%
1d5rA02 2.60.40.1110 Mainly Beta › Sandwich › Immunoglobulin-like › 0.61 46.0 4.52e-01 78.2% 97.7%
1k42A00 2.60.120.260 Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like 0.61 50.0 4.59e-01 90.3% 99.4%
3r8qA01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.61 38.0 4.25e-01 92.7% 82.6%
3t30C00 2.60.120.340 Mainly Beta › Sandwich › Jelly Rolls › Nucleoplasmin core domain 0.61 43.0 4.73e-01 88.7% 94.7%
4wtxA00 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.61 42.0 4.64e-01 81.5% 89.7%
5utkA01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.61 38.0 4.27e-01 90.3% 84.4%
1fnfA01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.60 41.0 4.60e-01 82.3% 90.4%
1loxA02 2.60.60.20 Mainly Beta › Sandwich › Lipoxygenase-1 › PLAT/LH2 domain 0.60 41.0 4.33e-01 70.2% 77.5%
7sf2A02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.60 42.0 4.69e-01 87.9% 94.6%
1f15B00 2.60.120.530 Mainly Beta › Sandwich › Jelly Rolls › Cucumovirus coat protein, subunit A 0.60 53.0 4.67e-01 100.0% 80.5%
1n26A02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.60 38.0 4.54e-01 86.3% 100.0%
4icwA00 2.60.40.150 Mainly Beta › Sandwich › Immunoglobulin-like › C2 domain 0.60 42.0 4.13e-01 71.0% 96.9%
3b83C00 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.59 38.0 4.17e-01 87.1% 79.8%
4zchA01 2.60.120.40 Mainly Beta › Sandwich › Jelly Rolls › 0.59 49.0 4.89e-01 91.1% 100.0%
3tesA00 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.59 39.0 4.33e-01 88.7% 86.2%
4p02B03 2.60.120.260 Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like 0.59 49.0 4.73e-01 91.1% 94.4%
1guiA00 2.60.120.260 Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like 0.59 48.0 4.47e-01 87.9% 100.0%
1xe0C00 2.60.120.340 Mainly Beta › Sandwich › Jelly Rolls › Nucleoplasmin core domain 0.59 43.0 4.64e-01 88.7% 93.1%
1o59A02 2.60.120.260 Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like 0.59 49.0 4.78e-01 91.1% 99.3%
2je8A02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.59 46.0 4.86e-01 82.3% 94.5%
1tg7A04 2.60.120.260 Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like 0.59 49.0 4.45e-01 91.1% 83.5%
4lplA00 2.60.120.260 Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like 0.58 49.0 4.76e-01 92.7% 100.0%
5z1aA02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.58 46.0 4.72e-01 83.1% 88.1%
1wfnA01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.58 39.0 4.47e-01 88.7% 96.6%
3gqqA00 2.70.50.40 Mainly Beta › Distorted Sandwich › Coagulation Factor XIII; Chain A, domain 1 › GMP phosphodiesterase, delta subunit 0.58 50.0 4.57e-01 95.2% 77.2%
3bgaA02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.58 44.0 4.66e-01 82.3% 90.1%
2c4xA02 2.60.120.260 Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like 0.57 48.0 4.52e-01 92.7% 99.4%
1x5hA00 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.57 40.0 3.92e-01 92.7% 66.7%
3ks7A02 2.60.120.230 Mainly Beta › Sandwich › Jelly Rolls › 0.57 47.0 4.24e-01 91.9% 98.9%
3l9bA00 2.60.40.150 Mainly Beta › Sandwich › Immunoglobulin-like › C2 domain 0.57 40.0 4.07e-01 73.4% 97.6%
8hhvA01 2.60.120.260 Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like 0.57 44.0 4.44e-01 83.9% 82.8%
2cjsA01 2.60.40.150 Mainly Beta › Sandwich › Immunoglobulin-like › C2 domain 0.57 40.0 3.75e-01 72.6% 80.4%
2xomA00 2.60.120.260 Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like 0.57 47.0 4.53e-01 91.1% 100.0%
1yq5A00 2.60.120.670 Mainly Beta › Sandwich › Jelly Rolls › Minor capsid protein. 0.57 47.0 4.51e-01 91.1% 95.8%
2c9aA01 2.60.120.200 Mainly Beta › Sandwich › Jelly Rolls › 0.57 46.0 4.29e-01 90.3% 96.9%
3b2dC00 2.60.40.770 Mainly Beta › Sandwich › Immunoglobulin-like › 0.57 45.0 4.34e-01 84.7% 90.6%
2jkbA01 2.60.120.200 Mainly Beta › Sandwich › Jelly Rolls › 0.57 47.0 4.17e-01 93.5% 92.2%
3kwuA00 2.60.40.150 Mainly Beta › Sandwich › Immunoglobulin-like › C2 domain 0.56 41.0 4.03e-01 75.8% 92.6%
1x5lA01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.56 37.0 4.30e-01 89.5% 95.5%
2gysA02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.56 41.0 4.45e-01 79.8% 92.2%
2wq4A01 2.60.120.760 Mainly Beta › Sandwich › Jelly Rolls › 0.56 46.0 4.61e-01 90.3% 99.2%
1tme200 2.60.120.20 Mainly Beta › Sandwich › Jelly Rolls › 0.56 49.0 3.96e-01 100.0% 89.4%
3vi3A02 2.60.40.1460 Mainly Beta › Sandwich › Immunoglobulin-like › Integrin domains. Chain A, domain 2 0.56 45.0 4.22e-01 86.3% 90.8%
3rwnB00 2.60.120.1120 Mainly Beta › Sandwich › Jelly Rolls › Sf6-type phage tail needle knob 0.56 46.0 4.31e-01 91.1% 90.3%
1yi9A02 2.60.120.230 Mainly Beta › Sandwich › Jelly Rolls › 0.55 44.0 4.30e-01 90.3% 78.1%
1wckA00 2.60.120.40 Mainly Beta › Sandwich › Jelly Rolls › 0.55 46.0 4.49e-01 91.1% 94.1%
4ht1T00 2.60.120.40 Mainly Beta › Sandwich › Jelly Rolls › 0.55 45.0 4.50e-01 90.3% 96.2%
2vmhA00 2.60.120.1060 Mainly Beta › Sandwich › Jelly Rolls › NPCBM/NEW2 domain 0.55 46.0 4.41e-01 100.0% 78.2%
5t5lA00 2.60.120.200 Mainly Beta › Sandwich › Jelly Rolls › 0.55 45.0 3.73e-01 89.5% 99.1%
3waiA02 2.60.40.3390 Mainly Beta › Sandwich › Immunoglobulin-like › 0.55 37.0 4.16e-01 71.0% 92.5%
4mxwD00 2.60.120.40 Mainly Beta › Sandwich › Jelly Rolls › 0.55 45.0 4.40e-01 90.3% 98.5%
4jpqA00 2.60.40.1190 Mainly Beta › Sandwich › Immunoglobulin-like › 0.55 44.0 3.75e-01 89.5% 81.3%
2vsdA00 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.55 37.0 4.16e-01 79.8% 93.5%
4npjB02 2.60.40.150 Mainly Beta › Sandwich › Immunoglobulin-like › C2 domain 0.54 39.0 3.82e-01 75.8% 94.4%
2df7A02 2.60.120.660 Mainly Beta › Sandwich › Jelly Rolls › icosahedral virus 0.54 44.0 4.32e-01 90.3% 93.6%
4l8jA02 2.40.30.170 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Efflux pump adaptor protein, beta barrel domain 0.54 39.0 4.39e-01 92.7% 100.0%
1x5kA01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.54 38.0 4.10e-01 77.4% 88.1%
3fppA01 2.40.30.170 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Efflux pump adaptor protein, beta barrel domain 0.54 39.0 4.15e-01 92.7% 89.4%
1pm4A00 2.60.120.510 Mainly Beta › Sandwich › Jelly Rolls › Mitogen Ypm 0.54 41.0 4.22e-01 90.3% 87.2%
4nx9A02 2.60.40.4390 Mainly Beta › Sandwich › Immunoglobulin-like › 0.52 41.0 4.15e-01 84.7% 84.3%
1wlfA01 2.40.40.20 Mainly Beta › Beta Barrel › Barwin-like endoglucanases › 0.52 34.0 3.95e-01 90.3% 98.8%
7jooC01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.50 37.0 4.13e-01 84.7% 99.0%
ECOD (93)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3552528 10.2.1.0 ↗ beta sandwiches › jelly-roll › Nucleoplasmin-like/VP (viral coat and capsid proteins) › Nucleoplasmin-like/VP (viral coat and capsid proteins) 0.80 70.0 4.89e-01 92.7% 43.6%
3907242 10.2.1.5 ↗ beta sandwiches › jelly-roll › Nucleoplasmin-like/VP (viral coat and capsid proteins) › Nucleoplasmin-like/VP (viral coat and capsid proteins) › TGFb_propeptide 0.80 74.0 5.86e-01 100.0% 74.2%
4293266 10.2.1.97 ↗ beta sandwiches › jelly-roll › Nucleoplasmin-like/VP (viral coat and capsid proteins) › Nucleoplasmin-like/VP (viral coat and capsid proteins) › TGF_beta 0.79 69.0 5.02e-01 91.9% 46.2%
None — 0.79 69.0 4.88e-01 92.7% 44.2%
4985337 11.1.1.1423 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › DUF7407 0.74 45.0 5.26e-01 85.5% 84.4%
5083569 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.73 45.0 5.44e-01 86.3% 95.0%
4932670 10.1.2.0 ↗ beta sandwiches › jelly-roll › Concanavalin A-like › GOLD domain-like (DEPRECATED) 0.73 54.0 6.03e-01 82.3% 100.0%
5039364 10.1.2.0 ↗ beta sandwiches › jelly-roll › Concanavalin A-like › GOLD domain-like (DEPRECATED) 0.72 49.0 5.63e-01 80.6% 95.6%
4955308 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.72 45.0 5.46e-01 85.5% 96.2%
3309702 207.1.1.43 ↗ beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › LRR_3 0.72 64.0 4.15e-01 97.6% 34.1%
3378079 207.1.1.119 ↗ beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › LRR_13 0.70 64.0 4.15e-01 100.0% 32.6%
3949275 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.70 46.0 5.31e-01 86.3% 92.2%
3307787 207.1.1.43 ↗ beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › LRR_3 0.69 62.0 4.07e-01 97.6% 32.9%
5062030 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.69 45.0 5.10e-01 85.5% 86.3%
2546336 10.32.1.90 ↗ beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like › CatAgl_D1 0.69 59.0 5.29e-01 93.5% 93.1%
4368632 10.32.1.266 ↗ beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like › GldH_lipo 0.68 59.0 5.70e-01 92.7% 99.3%
3619410 10.40.1.1 ↗ beta sandwiches › jelly-roll › PHR domain › PHR domain › PHR 0.68 59.0 5.25e-01 92.7% 96.0%
5083911 10.1.2.0 ↗ beta sandwiches › jelly-roll › Concanavalin A-like › GOLD domain-like (DEPRECATED) 0.68 57.0 5.03e-01 90.3% 96.1%
5020148 10.1.2.0 ↗ beta sandwiches › jelly-roll › Concanavalin A-like › GOLD domain-like (DEPRECATED) 0.68 57.0 5.23e-01 91.1% 99.4%
2884908 10.32.1.0 ↗ beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like 0.67 56.0 4.97e-01 91.1% 80.8%
3294967 10.32.1.0 ↗ beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like 0.67 61.0 5.48e-01 100.0% 95.9%
3906085 10.2.1.0 ↗ beta sandwiches › jelly-roll › Nucleoplasmin-like/VP (viral coat and capsid proteins) › Nucleoplasmin-like/VP (viral coat and capsid proteins) 0.67 61.0 5.49e-01 100.0% 95.9%
4953493 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.66 42.0 4.99e-01 77.4% 92.9%
4002686 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.66 44.0 4.91e-01 85.5% 87.4%
4234325 10.32.1.18 ↗ beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like › Endotoxin_C 0.66 56.0 5.07e-01 91.1% 90.3%
4999080 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.65 43.0 4.43e-01 79.8% 69.2%
3817425 10.32.1.0 ↗ beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like 0.65 58.0 5.03e-01 98.4% 96.4%
3521582 11.2.1.8 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain › PTEN_C2 0.65 49.0 4.78e-01 78.2% 97.8%
3319846 10.32.1.192 ↗ beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like › C-JID 0.65 56.0 5.31e-01 91.9% 89.7%
3348395 10.2.1.55 ↗ beta sandwiches › jelly-roll › Nucleoplasmin-like/VP (viral coat and capsid proteins) › Nucleoplasmin-like/VP (viral coat and capsid proteins) › NPL 0.65 48.0 5.12e-01 89.5% 90.5%
3830721 207.1.1.43 ↗ beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › LRR_3 0.65 58.0 3.84e-01 97.6% 37.4%
3312078 207.1.1.119 ↗ beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › LRR_13 0.65 58.0 4.45e-01 97.6% 62.5%
3484470 11.2.1.55 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain › C2_SYDE 0.65 45.0 4.25e-01 71.8% 90.7%
3884808 10.10.1.1 ↗ beta sandwiches › jelly-roll › Lipase/lipooxygenase domain (PLAT/LH2 domain) › Lipase/lipooxygenase domain (PLAT/LH2 domain) › PLAT 0.65 45.0 4.58e-01 71.0% 75.8%
5058689 10.1.2.0 ↗ beta sandwiches › jelly-roll › Concanavalin A-like › GOLD domain-like (DEPRECATED) 0.64 48.0 5.26e-01 84.7% 99.0%
5057270 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.64 44.0 4.87e-01 83.9% 88.0%
3830329 207.1.1.0 ↗ beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats 0.64 55.0 4.53e-01 95.2% 63.5%
3780293 11.1.3.4 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Cu,Zn superoxide dismutase-like › CHRD 0.64 53.0 5.44e-01 89.5% 97.5%
3541359 11.1.1.538 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › CHRD 0.63 52.0 5.30e-01 87.1% 98.3%
4466626 10.32.1.244 ↗ beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like › PF29989 0.63 49.0 5.12e-01 93.5% 91.8%
3591572 10.32.1.0 ↗ beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like 0.63 52.0 5.29e-01 91.9% 90.0%
4955347 10.1.2.0 ↗ beta sandwiches › jelly-roll › Concanavalin A-like › GOLD domain-like (DEPRECATED) 0.63 49.0 5.27e-01 82.3% 98.1%
4985684 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.63 43.0 4.83e-01 79.8% 90.5%
3249004 11.2.1.8 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain › PTEN_C2 0.63 47.0 4.76e-01 78.2% 99.2%
5060986 11.1.1.103 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › CARDB 0.63 45.0 5.01e-01 85.5% 96.8%
5044786 10.1.2.0 ↗ beta sandwiches › jelly-roll › Concanavalin A-like › GOLD domain-like (DEPRECATED) 0.62 52.0 5.35e-01 90.3% 96.5%
4014223 10.2.1.0 ↗ beta sandwiches › jelly-roll › Nucleoplasmin-like/VP (viral coat and capsid proteins) › Nucleoplasmin-like/VP (viral coat and capsid proteins) 0.62 54.0 5.10e-01 98.4% 86.5%
5003202 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.62 44.0 4.81e-01 79.0% 90.0%
4937335 10.1.2.0 ↗ beta sandwiches › jelly-roll › Concanavalin A-like › GOLD domain-like (DEPRECATED) 0.61 52.0 4.70e-01 91.9% 93.5%
3947769 10.32.1.10 ↗ beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like › BcsB 0.61 51.0 4.98e-01 91.9% 94.3%
3805836 10.32.1.0 ↗ beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like 0.61 53.0 5.15e-01 94.4% 100.0%
4609141 11.2.1.8 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain › PTEN_C2 0.61 46.0 4.45e-01 78.2% 97.1%
4015352 10.9.1.0 ↗ beta sandwiches › jelly-roll › C-terminal domain of mullusc hemocyanin › C-terminal domain of mullusc hemocyanin 0.61 43.0 4.26e-01 72.6% 93.1%
3606438 11.2.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain 0.61 44.0 4.14e-01 75.8% 96.1%
4399012 10.32.1.198 ↗ beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like › PP2 0.60 49.0 4.70e-01 88.7% 100.0%
5023642 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.60 40.0 4.64e-01 71.8% 93.3%
3605972 10.32.1.0 ↗ beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like 0.60 49.0 5.14e-01 91.1% 98.2%
4615128 10.32.1.0 ↗ beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like 0.60 50.0 4.73e-01 91.1% 98.0%
3941823 10.32.1.8 ↗ beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like › CBM_4_9 0.59 50.0 4.69e-01 91.1% 100.0%
3233104 11.2.1.8 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain › PTEN_C2 0.59 44.0 4.14e-01 78.2% 90.3%
4943023 10.1.2.0 ↗ beta sandwiches › jelly-roll › Concanavalin A-like › GOLD domain-like (DEPRECATED) 0.59 49.0 4.82e-01 88.7% 91.5%
3477359 11.2.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain 0.59 42.0 4.26e-01 73.4% 100.0%
1588 11.1.1.14 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Glyco_hydro_2 0.59 46.0 4.84e-01 82.3% 93.7%
3889345 10.3.1.1 ↗ beta sandwiches › jelly-roll › TNF-like › TNF-like › TNF 0.59 49.0 4.67e-01 91.1% 93.1%
4048590 10.32.1.53 ↗ beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like › GalBD_like 0.58 48.0 4.33e-01 90.3% 95.4%
4405706 10.32.1.243 ↗ beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like › PF29992 0.58 49.0 4.97e-01 93.5% 95.0%
4034212 10.32.1.0 ↗ beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like 0.58 48.0 4.18e-01 90.3% 97.9%
4177785 10.1.1.10 ↗ beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases › MAM 0.58 42.0 4.41e-01 82.3% 84.5%
3621194 11.2.1.1 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain › C2 0.58 42.0 4.19e-01 75.0% 85.2%
5039235 10.1.2.0 ↗ beta sandwiches › jelly-roll › Concanavalin A-like › GOLD domain-like (DEPRECATED) 0.58 44.0 4.60e-01 79.8% 97.3%
5084049 10.1.2.0 ↗ beta sandwiches › jelly-roll › Concanavalin A-like › GOLD domain-like (DEPRECATED) 0.58 47.0 4.76e-01 91.9% 89.6%
4943630 11.1.1.1398 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Bgal_small_N 0.58 42.0 4.54e-01 86.3% 90.5%
5039097 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.57 45.0 4.71e-01 82.3% 93.6%
3396566 10.32.1.234 ↗ beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like › PGAP1_3rd 0.56 47.0 4.65e-01 91.9% 88.1%
3893729 10.4.1.4 ↗ beta sandwiches › jelly-roll › Spermadhesin, CUB domain › Spermadhesin, CUB domain › C5_CUB 0.56 45.0 4.75e-01 91.9% 98.2%
5081344 10.1.2.0 ↗ beta sandwiches › jelly-roll › Concanavalin A-like › GOLD domain-like (DEPRECATED) 0.56 45.0 4.01e-01 86.3% 98.9%
5018595 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.56 42.0 4.49e-01 79.8% 91.4%
2704186 10.32.1.30 ↗ beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like › NPCBM 0.56 46.0 4.38e-01 98.4% 75.3%
3764995 11.2.1.43 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain › C2+FerI 0.56 38.0 3.43e-01 70.2% 73.3%
5039301 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.56 42.0 4.33e-01 78.2% 87.0%
5064808 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.56 39.0 4.35e-01 84.7% 92.6%
3821517 10.32.1.38 ↗ beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like › Malectin_like 0.55 45.0 4.25e-01 90.3% 95.5%
1095601 10.3.1.6 ↗ beta sandwiches › jelly-roll › TNF-like › TNF-like › Phage_tail_NK 0.55 45.0 4.27e-01 91.9% 90.4%
3543731 10.3.1.1 ↗ beta sandwiches › jelly-roll › TNF-like › TNF-like › TNF 0.55 46.0 4.34e-01 93.5% 94.8%
3457300 11.2.1.1 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain › C2 0.55 46.0 2.98e-01 91.1% 85.5%
3898059 11.2.1.43 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain › C2+FerI 0.54 38.0 2.83e-01 73.4% 38.3%
3659523 11.2.1.1 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain › C2 0.54 38.0 3.87e-01 73.4% 96.0%
3406853 10.4.1.0 ↗ beta sandwiches › jelly-roll › Spermadhesin, CUB domain › Spermadhesin, CUB domain 0.54 43.0 4.44e-01 91.9% 92.5%
3232214 11.2.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain 0.53 39.0 3.57e-01 75.8% 88.5%
4930609 10.1.2.0 ↗ beta sandwiches › jelly-roll › Concanavalin A-like › GOLD domain-like (DEPRECATED) 0.53 44.0 4.26e-01 91.9% 80.7%
3913258 10.3.1.2 ↗ beta sandwiches › jelly-roll › TNF-like › TNF-like › C1q 0.53 43.0 4.19e-01 90.3% 95.7%
4162144 11.1.1.2 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › fn3 0.52 38.0 4.07e-01 85.5% 88.2%
3433614 11.2.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain 0.51 37.0 3.48e-01 75.8% 85.2%
D2 medium residues 294-390
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00019.26 best TGF_beta 62.6 7.30e-17 99.0% 100.0%
CATH (7)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2bhkA00 2.10.90.10 Mainly Beta › Ribbon › Cystine Knot Cytokines, subunit B › Cystine-knot cytokines 0.82 76.0 7.43e-01 100.0% 98.1%
1tgjA00 2.10.90.10 Mainly Beta › Ribbon › Cystine Knot Cytokines, subunit B › Cystine-knot cytokines 0.82 77.0 7.31e-01 100.0% 88.4%
5f3bD00 2.10.90.10 Mainly Beta › Ribbon › Cystine Knot Cytokines, subunit B › Cystine-knot cytokines 0.70 65.0 6.35e-01 99.0% 94.2%
1azpA00 2.40.50.40 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › 0.69 26.0 3.15e-01 78.4% 50.0%
8enbA01 2.10.90.10 Mainly Beta › Ribbon › Cystine Knot Cytokines, subunit B › Cystine-knot cytokines 0.67 52.0 5.61e-01 99.0% 97.6%
4uoiC00 3.30.160.890 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Hepatitis C virus envelope glycoprotein E1, chain C 0.61 23.0 3.09e-01 77.3% 62.7%
1fl7D00 2.10.90.10 Mainly Beta › Ribbon › Cystine Knot Cytokines, subunit B › Cystine-knot cytokines 0.58 45.0 4.43e-01 97.9% 77.4%
ECOD (27)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
None — 0.87 66.0 4.61e-01 100.0% 28.1%
3938762 385.1.1.2 ↗ few secondary structure elements › Cystine-knot cytokines › Cystine-knot cytokines › Cystine-knot cytokines › TGF_beta 0.87 66.0 7.27e-01 100.0% 96.2%
4550201 10.2.1.0 ↗ beta sandwiches › jelly-roll › Nucleoplasmin-like/VP (viral coat and capsid proteins) › Nucleoplasmin-like/VP (viral coat and capsid proteins) 0.85 80.0 5.20e-01 100.0% 26.1%
3938564 385.1.1.2 ↗ few secondary structure elements › Cystine-knot cytokines › Cystine-knot cytokines › Cystine-knot cytokines › TGF_beta 0.84 64.0 4.45e-01 100.0% 27.0%
3937311 385.1.1.2 ↗ few secondary structure elements › Cystine-knot cytokines › Cystine-knot cytokines › Cystine-knot cytokines › TGF_beta 0.84 78.0 7.61e-01 99.0% 99.0%
3552528 10.2.1.0 ↗ beta sandwiches › jelly-roll › Nucleoplasmin-like/VP (viral coat and capsid proteins) › Nucleoplasmin-like/VP (viral coat and capsid proteins) 0.83 78.0 5.14e-01 100.0% 27.5%
3873599 385.1.1.2 ↗ few secondary structure elements › Cystine-knot cytokines › Cystine-knot cytokines › Cystine-knot cytokines › TGF_beta 0.83 78.0 6.26e-01 100.0% 56.9%
4526608 385.1.1.2 ↗ few secondary structure elements › Cystine-knot cytokines › Cystine-knot cytokines › Cystine-knot cytokines › TGF_beta 0.83 77.0 5.26e-01 99.0% 33.1%
None — 0.82 78.0 5.10e-01 100.0% 27.9%
3906893 385.1.1.2 ↗ few secondary structure elements › Cystine-knot cytokines › Cystine-knot cytokines › Cystine-knot cytokines › TGF_beta 0.82 76.0 7.31e-01 100.0% 95.5%
3526558 385.1.1.2 ↗ few secondary structure elements › Cystine-knot cytokines › Cystine-knot cytokines › Cystine-knot cytokines › TGF_beta 0.82 76.0 7.48e-01 100.0% 99.0%
3244528 385.1.1.2 ↗ few secondary structure elements › Cystine-knot cytokines › Cystine-knot cytokines › Cystine-knot cytokines › TGF_beta 0.81 77.0 7.45e-01 100.0% 97.1%
3863128 385.1.1.2 ↗ few secondary structure elements › Cystine-knot cytokines › Cystine-knot cytokines › Cystine-knot cytokines › TGF_beta 0.81 76.0 7.40e-01 100.0% 95.2%
3931584 385.1.1.2 ↗ few secondary structure elements › Cystine-knot cytokines › Cystine-knot cytokines › Cystine-knot cytokines › TGF_beta 0.80 73.0 7.02e-01 99.0% 85.5%
3621431 385.1.1.2 ↗ few secondary structure elements › Cystine-knot cytokines › Cystine-knot cytokines › Cystine-knot cytokines › TGF_beta 0.79 75.0 7.27e-01 100.0% 94.3%
3929308 385.1.1.2 ↗ few secondary structure elements › Cystine-knot cytokines › Cystine-knot cytokines › Cystine-knot cytokines › TGF_beta 0.79 71.0 7.18e-01 100.0% 96.8%
3480457 385.1.1.0 ↗ few secondary structure elements › Cystine-knot cytokines › Cystine-knot cytokines › Cystine-knot cytokines 0.78 73.0 6.84e-01 100.0% 92.2%
3933681 385.1.1.2 ↗ few secondary structure elements › Cystine-knot cytokines › Cystine-knot cytokines › Cystine-knot cytokines › TGF_beta 0.78 73.0 5.12e-01 100.0% 34.9%
2123380 385.1.1.2 ↗ few secondary structure elements › Cystine-knot cytokines › Cystine-knot cytokines › Cystine-knot cytokines › TGF_beta 0.76 71.0 6.82e-01 100.0% 91.7%
3621436 385.1.1.2 ↗ few secondary structure elements › Cystine-knot cytokines › Cystine-knot cytokines › Cystine-knot cytokines › TGF_beta 0.76 70.0 6.83e-01 97.9% 98.1%
3779843 10.2.1.0 ↗ beta sandwiches › jelly-roll › Nucleoplasmin-like/VP (viral coat and capsid proteins) › Nucleoplasmin-like/VP (viral coat and capsid proteins) 0.76 70.0 4.67e-01 100.0% 27.4%
3885729 385.1.1.2 ↗ few secondary structure elements › Cystine-knot cytokines › Cystine-knot cytokines › Cystine-knot cytokines › TGF_beta 0.74 66.0 6.63e-01 100.0% 94.9%
2898183 385.1.1.2 ↗ few secondary structure elements › Cystine-knot cytokines › Cystine-knot cytokines › Cystine-knot cytokines › TGF_beta 0.74 69.0 6.57e-01 100.0% 89.2%
3886214 385.1.1.2 ↗ few secondary structure elements › Cystine-knot cytokines › Cystine-knot cytokines › Cystine-knot cytokines › TGF_beta 0.73 68.0 6.76e-01 100.0% 97.0%
3928845 385.1.1.2 ↗ few secondary structure elements › Cystine-knot cytokines › Cystine-knot cytokines › Cystine-knot cytokines › TGF_beta 0.68 63.0 6.30e-01 99.0% 97.0%
3847863 385.1.1.8 ↗ few secondary structure elements › Cystine-knot cytokines › Cystine-knot cytokines › Cystine-knot cytokines › DAN 0.59 48.0 5.00e-01 100.0% 95.6%
3964837 512.1.1.1 ↗ a+b two layers › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) › PmbA_TldD_1st 0.51 30.0 3.28e-01 93.8% 72.0%