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Tegument_protein_of_HCMV
Euk-VirMurid_betaherpesvirus_1
Tegument_protein_of_HCMV__YP_214046__Murid_betaherpesvirus_1__10366
Identity
- Accession:
- YP_214046 ↗
- Protein ID:
- Tegument_protein_of_HCMV
- Kingdom:
- euk
Quality
53.5
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Muromegalovirus›
Murid_betaherpesvirus_1
TaxID: 10366
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 20-88_233-298
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF06070.16 best | Herpes_UL32 | 42.6 | 2.60e-11 | 52.6% | 6.3% |
CATH (31)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3x0uB01 | 1.20.190.10 | Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain | 0.66 | 54.0 | 4.44e-01 | 88.1% | 84.8% |
| 1dlcA01 | 1.20.190.10 | Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain | 0.64 | 51.0 | 4.32e-01 | 85.2% | 84.7% |
| 3lmfA00 | 1.20.1270.360 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.62 | 41.0 | 4.54e-01 | 82.2% | 82.6% |
| 5cwhA01 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.62 | 44.0 | 4.21e-01 | 81.5% | 62.8% |
| 1zb1A00 | 1.25.40.280 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › alix/aip1 like domains | 0.61 | 51.0 | 3.75e-01 | 90.4% | 79.8% |
| 2fbnA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.61 | 42.0 | 4.06e-01 | 71.1% | 62.7% |
| 2pm6A00 | 1.25.40.1030 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.60 | 46.0 | 3.46e-01 | 81.5% | 78.0% |
| 3zheD01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.60 | 44.0 | 3.81e-01 | 76.3% | 65.9% |
| 4p3fA00 | 1.10.3450.40 | Mainly Alpha › Orthogonal Bundle › Hyaluronidase domain-like › Signal recognition particle, SRP68 subunit, RNA-binding domain | 0.59 | 51.0 | 4.48e-01 | 91.1% | 85.5% |
| 5m9dA00 | 1.25.40.90 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.58 | 44.0 | 4.38e-01 | 83.0% | 77.5% |
| 4g1tA01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.58 | 41.0 | 4.27e-01 | 73.3% | 90.2% |
| 2gscC00 | 1.20.1440.60 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence | 0.57 | 39.0 | 4.31e-01 | 82.2% | 86.4% |
| 4by6A01 | 1.25.40.790 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.57 | 45.0 | 3.60e-01 | 84.4% | 65.0% |
| 1zu2A00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.56 | 45.0 | 4.33e-01 | 85.2% | 82.3% |
| 4l6rA02 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.56 | 52.0 | 4.01e-01 | 100.0% | 84.2% |
| 3snxA00 | 1.25.40.390 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.56 | 48.0 | 3.38e-01 | 93.3% | 49.7% |
| 3wi3B00 | 1.20.58.2130 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.56 | 46.0 | 3.92e-01 | 87.4% | 84.0% |
| 4dwlA00 | 1.20.1440.60 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence | 0.54 | 37.0 | 4.09e-01 | 83.0% | 87.0% |
| 3csvA02 | 3.90.1200.10 | Alpha Beta › Alpha-Beta Complex › Aminoglycoside 3'-phosphotransferase; Chain: A, domain 2 › Aminoglycoside phosphotransferase (APH), C-terminal lobe | 0.54 | 43.0 | 3.55e-01 | 83.7% | 80.8% |
| 1xg2B00 | 1.20.140.40 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein | 0.54 | 39.0 | 3.75e-01 | 83.0% | 66.2% |
| 2i2oA00 | 1.25.40.180 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.54 | 46.0 | 3.99e-01 | 93.3% | 99.1% |
| 3f1bA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.53 | 42.0 | 3.87e-01 | 85.2% | 90.2% |
| 4yvoA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.53 | 42.0 | 4.43e-01 | 86.7% | 95.8% |
| 6tepC02 | 3.30.70.890 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › GHMP kinase, C-terminal domain | 0.52 | 41.0 | 3.80e-01 | 87.4% | 64.6% |
| 1paqA00 | 1.25.40.180 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.51 | 40.0 | 3.83e-01 | 83.7% | 90.7% |
| 1x8zB00 | 1.20.140.40 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein | 0.51 | 35.0 | 3.46e-01 | 83.7% | 64.6% |
| 4h79A00 | 1.10.520.40 | Mainly Alpha › Orthogonal Bundle › Peroxidase; domain 1 › CRISPR-associated protein Cse2 | 0.51 | 45.0 | 4.15e-01 | 98.5% | 91.0% |
| 4i1aA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.50 | 42.0 | 3.39e-01 | 91.1% | 54.7% |
| 1hw1A02 | 1.20.120.530 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like | 0.50 | 37.0 | 3.66e-01 | 77.8% | 98.7% |
| 4r42A01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.50 | 40.0 | 3.55e-01 | 83.0% | 89.8% |
| 4fjqA02 | 1.50.10.130 | Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › Terpene synthase, N-terminal domain | 0.50 | 45.0 | 4.24e-01 | 100.0% | 95.1% |
ECOD (36)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3240017 | 109.4.1.1136 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HAT_PRP39_N | 0.66 | 49.0 | 3.25e-01 | 76.3% | 20.0% |
| 3412382 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.64 | 43.0 | 4.19e-01 | 77.8% | 62.1% |
| 3530477 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.62 | 47.0 | 4.27e-01 | 77.8% | 66.3% |
| 3302335 | 109.4.1.634 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › EST1 | 0.62 | 47.0 | 4.11e-01 | 80.7% | 81.0% |
| 4946155 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.62 | 55.0 | 5.02e-01 | 95.6% | 96.6% |
| 4959917 | 109.4.1.207 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HEAT_2 | 0.60 | 55.0 | 3.73e-01 | 99.3% | 34.0% |
| 3416038 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.60 | 43.0 | 4.40e-01 | 83.7% | 76.9% |
| 3824447 | 109.4.1.843 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › EFR3_ARM | 0.59 | 47.0 | 3.20e-01 | 85.2% | 46.5% |
| 3405706 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.58 | 41.0 | 4.23e-01 | 83.0% | 76.2% |
| 3789118 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.57 | 47.0 | 4.37e-01 | 89.6% | 89.7% |
| 3475661 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.57 | 41.0 | 4.00e-01 | 83.7% | 69.0% |
| 3905481 | 109.25.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › GPCR-autoproteolysis inducing domain subdomain A › GPCR-autoproteolysis inducing domain subdomain A | 0.57 | 44.0 | 3.99e-01 | 82.2% | 76.8% |
| 3622326 | 109.25.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › GPCR-autoproteolysis inducing domain subdomain A › GPCR-autoproteolysis inducing domain subdomain A › GAIN | 0.56 | 43.0 | 4.32e-01 | 80.0% | 88.1% |
| 5002523 | 3861.1.1.3 ↗ | alpha bundles › Mitochondrial translocator protein (TSPO) › Mitochondrial translocator protein (TSPO) › Mitochondrial translocator protein (TSPO) › PF30661 | 0.56 | 44.0 | 4.02e-01 | 81.5% | 92.9% |
| 3770345 | 602.2.1.3 ↗ | alpha arrays › L-aspartase middle domain-like › RNA-binding protein She2p › RNA-binding protein She2p › PPP1R21_helical | 0.56 | 44.0 | 3.56e-01 | 83.0% | 61.2% |
| 3411108 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.55 | 39.0 | 3.97e-01 | 83.7% | 72.6% |
| 3401839 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.55 | 43.0 | 4.37e-01 | 83.0% | 81.5% |
| 3996622 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.55 | 43.0 | 4.24e-01 | 83.0% | 75.9% |
| 3226467 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.55 | 43.0 | 4.37e-01 | 82.2% | 82.2% |
| 3502871 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.54 | 34.0 | 3.49e-01 | 83.7% | 62.7% |
| 3730143 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.54 | 46.0 | 3.82e-01 | 92.6% | 68.4% |
| 3879044 | 174.1.1.43 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › CD20 | 0.54 | 39.0 | 4.12e-01 | 83.0% | 80.8% |
| 3711513 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.54 | 46.0 | 3.25e-01 | 95.6% | 37.6% |
| 3412672 | 109.4.1.170 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › CLASP_N | 0.54 | 47.0 | 2.94e-01 | 97.8% | 60.1% |
| 3247549 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.54 | 41.0 | 4.05e-01 | 83.0% | 75.7% |
| 3289148 | 109.4.1.194 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_10 | 0.54 | 44.0 | 3.82e-01 | 91.1% | 76.4% |
| 3627459 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.53 | 42.0 | 4.01e-01 | 83.0% | 83.2% |
| 3408340 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.53 | 42.0 | 4.00e-01 | 83.0% | 87.1% |
| 3532924 | 174.1.1.43 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › CD20 | 0.53 | 42.0 | 3.86e-01 | 83.0% | 75.3% |
| 3909550 | 633.21.1.0 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 | 0.52 | 41.0 | 4.04e-01 | 83.0% | 77.2% |
| 3585409 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.52 | 40.0 | 3.06e-01 | 83.0% | 46.3% |
| 3899721 | 174.1.1.43 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › CD20 | 0.51 | 41.0 | 3.83e-01 | 83.7% | 78.2% |
| 3994022 | 633.21.1.23 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › CD20 | 0.51 | 40.0 | 3.99e-01 | 82.2% | 80.7% |
| 3780523 | 633.23.1.34 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin › CD20 | 0.51 | 40.0 | 3.82e-01 | 83.0% | 80.0% |
| 3936980 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.51 | 40.0 | 3.77e-01 | 83.0% | 85.5% |
| 3399701 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.51 | 38.0 | 3.84e-01 | 83.0% | 76.4% |
D2
high
residues 92-228
Domain cluster:
rep: E32__YP_007016436__Murid_betaherpesvirus_8__1261657__D75-209