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Threonylcarbamoyl_AMP_synthase

Euk-Vir

Pandoravirus_dulcis

Threonylcarbamoyl_AMP_synthase__YP_008318818__Pandoravirus_dulcis__1349409

Identity

Accession:
YP_008318818 ↗
Protein ID:
Threonylcarbamoyl_AMP_synthase
Kingdom:
euk

Quality

86.5 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 200-343
PDB
Domain cluster: rep: Threonylcarbamoyl_AMP_synthase__YP_009430141__Pandoravirus_salinus__1349410__D206-341
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00814.32 best TsaD 52.3 9.60e-14 99.3% 41.3%
D2 high residues 400-611
PDB
Domain cluster: rep: IMGVR_UViG_3300042094_000363-3300042094-Ga0453242_007407_1_669__D52-217
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF01300.25 best Sua5_yciO_yrdC 166.2 7.70e-49 85.9% 99.4%
D3 high residues 646-751
PDB
Domain cluster: rep: Threonylcarbamoyl_AMP_synthase__YP_009483771__Pandoravirus_quercus__2107709__D644-748
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF03481.20 best Sua5_C 43.6 6.10e-11 95.3% 60.8%
D4 high residues 764-999
PDB
Domain cluster: rep: ON548429__URC17455.1__X__00151__D178-370
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00899.28 best ThiF 118.7 3.40e-34 98.7% 81.1%
D5 medium residues 35-97
PDB
Domain cluster: representative
CATH (35)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
6obtA00 3.10.129.110 Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Polyketide synthase dehydratase 0.68 44.0 2.87e-01 93.7% 15.3%
1e3hA01 3.30.230.70 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › GHMP Kinase, N-terminal domain 0.68 48.0 3.21e-01 74.6% 25.8%
4k15A00 2.60.40.3860 Mainly Beta › Sandwich › Immunoglobulin-like › 0.67 47.0 3.70e-01 74.6% 53.6%
1bdgA02 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.65 52.0 3.85e-01 100.0% 33.5%
1ig8A02 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.65 51.0 4.01e-01 95.2% 40.3%
1y8cA02 2.20.25.110 Mainly Beta › Single Sheet › N-terminal domain of TfIIb › S-adenosyl-L-methionine-dependent methyltransferases 0.64 44.0 4.52e-01 73.0% 75.0%
1nbwA01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.64 44.0 3.48e-01 90.5% 34.8%
3aapA01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.63 50.0 4.05e-01 88.9% 51.2%
4cgyA03 2.70.20.10 Mainly Beta › Distorted Sandwich › Topoisomerase I; domain 3 › Topoisomerase I, domain 3 0.62 43.0 3.48e-01 74.6% 55.5%
5uj1A03 2.70.20.10 Mainly Beta › Distorted Sandwich › Topoisomerase I; domain 3 › Topoisomerase I, domain 3 0.60 42.0 3.14e-01 74.6% 56.7%
4oocA00 3.10.129.110 Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Polyketide synthase dehydratase 0.59 37.0 2.48e-01 93.7% 14.6%
2gaiA03 2.70.20.10 Mainly Beta › Distorted Sandwich › Topoisomerase I; domain 3 › Topoisomerase I, domain 3 0.59 41.0 3.36e-01 74.6% 56.9%
1ah5A03 3.30.160.40 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Porphobilinogen deaminase, C-terminal domain 0.57 36.0 3.28e-01 92.1% 45.3%
3nsjA02 2.60.40.150 Mainly Beta › Sandwich › Immunoglobulin-like › C2 domain 0.57 44.0 3.45e-01 82.5% 77.3%
3msyA01 3.30.390.10 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain 0.57 36.0 3.04e-01 93.7% 35.1%
3ztvA01 3.60.21.10 Alpha Beta › 4-Layer Sandwich › Purple Acid Phosphatase; chain A, domain 2 › Metallo-dependent phosphatases 0.56 48.0 2.98e-01 95.2% 93.7%
1jkfA03 3.30.360.10 Alpha Beta › 2-Layer Sandwich › Dihydrodipicolinate Reductase; domain 2 › Dihydrodipicolinate Reductase; domain 2 0.56 33.0 3.45e-01 84.1% 63.3%
4h61A00 3.10.450.580 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › Mediator complex, subunit Med6 0.55 38.0 3.01e-01 98.4% 32.8%
7a1rA01 2.60.40.150 Mainly Beta › Sandwich › Immunoglobulin-like › C2 domain 0.54 44.0 3.64e-01 92.1% 65.3%
1wnhA02 3.10.450.10 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.54 48.0 3.83e-01 96.8% 98.3%
3p09A00 3.40.710.10 Alpha Beta › 3-Layer(aba) Sandwich › Beta-lactamase › DD-peptidase/beta-lactamase superfamily 0.53 47.0 3.12e-01 100.0% 29.9%
7xhlD02 3.30.360.10 Alpha Beta › 2-Layer Sandwich › Dihydrodipicolinate Reductase; domain 2 › Dihydrodipicolinate Reductase; domain 2 0.53 43.0 2.80e-01 90.5% 18.7%
3jzyA00 2.60.40.150 Mainly Beta › Sandwich › Immunoglobulin-like › C2 domain 0.53 44.0 3.54e-01 92.1% 79.8%
2cm5A00 2.60.40.150 Mainly Beta › Sandwich › Immunoglobulin-like › C2 domain 0.53 43.0 3.38e-01 92.1% 63.6%
2pn5A10 2.60.40.690 Mainly Beta › Sandwich › Immunoglobulin-like › Alpha-macroglobulin, receptor-binding domain 0.53 39.0 3.08e-01 82.5% 69.2%
2b3rA00 2.60.40.150 Mainly Beta › Sandwich › Immunoglobulin-like › C2 domain 0.53 43.0 3.52e-01 92.1% 66.9%
1w15A00 2.60.40.150 Mainly Beta › Sandwich › Immunoglobulin-like › C2 domain 0.53 43.0 3.44e-01 92.1% 71.2%
1gmiA00 2.60.40.150 Mainly Beta › Sandwich › Immunoglobulin-like › C2 domain 0.53 42.0 3.38e-01 92.1% 57.0%
3w15A01 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.52 46.0 2.89e-01 100.0% 25.1%
2nq3A00 2.60.40.150 Mainly Beta › Sandwich › Immunoglobulin-like › C2 domain 0.51 41.0 3.31e-01 90.5% 61.1%
2i0oA00 3.60.40.10 Alpha Beta › 4-Layer Sandwich › Phosphatase 2c; domain 1 › PPM-type phosphatase domain 0.51 42.0 2.77e-01 93.7% 87.8%
2n59A00 2.60.40.2420 Mainly Beta › Sandwich › Immunoglobulin-like › 0.51 42.0 3.64e-01 93.7% 72.3%
2ep6A01 2.60.40.150 Mainly Beta › Sandwich › Immunoglobulin-like › C2 domain 0.51 41.0 3.37e-01 92.1% 79.5%
3b7yA00 2.60.40.150 Mainly Beta › Sandwich › Immunoglobulin-like › C2 domain 0.50 41.0 3.19e-01 92.1% 76.4%
2wuqB00 3.40.710.10 Alpha Beta › 3-Layer(aba) Sandwich › Beta-lactamase › DD-peptidase/beta-lactamase superfamily 0.50 44.0 2.89e-01 100.0% 26.5%
ECOD (76)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4539019 2484.1.1.10 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › TsaD 0.92 84.0 5.81e-01 96.8% 33.0%
4467784 2484.1.1.10 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › TsaD 0.89 78.0 5.69e-01 93.7% 38.1%
4975528 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.73 53.0 4.04e-01 92.1% 33.8%
3579807 101.1.2.709 ↗ alpha arrays › HTH › HTH › winged helix domain › Hexokinase_1 0.71 52.0 4.44e-01 98.4% 49.0%
4268179 2484.1.1.176 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Hexokinase_1+Hexokinase_2 0.69 56.0 3.29e-01 100.0% 10.8%
3940091 2484.5.1.2 ↗ mixed a+b and a/b › Ribonuclease H-like › RNaseH-like domain in reverse transcriptase › RNaseH-like domain in reverse transcriptase › RT_RNaseH 0.69 47.0 3.65e-01 71.4% 94.3%
4928236 2484.1.1.29 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Ppx-GppA 0.68 56.0 3.54e-01 92.1% 17.1%
3514856 1181.1.1.0 ↗ 0.68 50.0 4.80e-01 95.2% 68.0%
3976937 2484.1.1.178 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › SHS2_FTSA+FtsA 0.67 52.0 3.16e-01 92.1% 13.2%
5009779 2484.1.1.29 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Ppx-GppA 0.67 54.0 4.36e-01 90.5% 46.4%
5063324 2484.1.1.29 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Ppx-GppA 0.66 53.0 4.31e-01 90.5% 46.4%
5020335 2484.1.1.29 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Ppx-GppA 0.65 54.0 4.42e-01 95.2% 48.8%
3876259 2484.1.1.15 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › GDA1_CD39 0.65 53.0 3.88e-01 95.2% 33.2%
4978501 9.1.1.0 ↗ beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins 0.62 40.0 3.08e-01 93.7% 27.5%
3640818 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.62 56.0 3.98e-01 100.0% 42.2%
3592741 330.1.1.0 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.61 39.0 3.54e-01 92.1% 47.1%
3615641 330.1.1.0 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.61 39.0 3.55e-01 92.1% 47.1%
4136946 264.2.1.0 ↗ beta barrels › LigT-like › Prokaryotic type I DNA topoisomerase beta-barrel domain › Prokaryotic type I DNA topoisomerase beta-barrel domain 0.61 42.0 3.24e-01 74.6% 52.3%
3962989 222.1.1.0 ↗ a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase 0.60 37.0 3.26e-01 93.7% 39.0%
5003644 264.2.1.1 ↗ beta barrels › LigT-like › Prokaryotic type I DNA topoisomerase beta-barrel domain › Prokaryotic type I DNA topoisomerase beta-barrel domain › Topoisom_bac 0.60 42.0 3.40e-01 74.6% 55.2%
4414942 2484.1.1.25 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RuvC 0.60 47.0 3.61e-01 90.5% 35.6%
3597697 5.1.1.0 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 4-bladed 0.60 51.0 3.66e-01 100.0% 49.0%
4638438 2484.1.1.25 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RuvC 0.59 47.0 3.58e-01 90.5% 35.6%
4591470 264.2.1.0 ↗ beta barrels › LigT-like › Prokaryotic type I DNA topoisomerase beta-barrel domain › Prokaryotic type I DNA topoisomerase beta-barrel domain 0.59 42.0 3.22e-01 76.2% 61.3%
4113222 264.2.1.0 ↗ beta barrels › LigT-like › Prokaryotic type I DNA topoisomerase beta-barrel domain › Prokaryotic type I DNA topoisomerase beta-barrel domain 0.59 42.0 3.33e-01 77.8% 55.7%
3939200 264.2.1.0 ↗ beta barrels › LigT-like › Prokaryotic type I DNA topoisomerase beta-barrel domain › Prokaryotic type I DNA topoisomerase beta-barrel domain 0.59 41.0 3.29e-01 74.6% 54.6%
4069907 2484.1.1.25 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RuvC 0.58 46.0 3.46e-01 90.5% 33.5%
3882078 11.2.1.1 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain › C2 0.57 48.0 3.73e-01 92.1% 61.5%
3827309 244.3.1.0 ↗ a+b two layers › FAD-linked reductases, C-terminal domain-like › SufE/NifU › SufE/NifU 0.57 38.0 3.45e-01 93.7% 48.9%
3518382 2484.5.1.2 ↗ mixed a+b and a/b › Ribonuclease H-like › RNaseH-like domain in reverse transcriptase › RNaseH-like domain in reverse transcriptase › RT_RNaseH 0.57 45.0 4.14e-01 92.1% 65.9%
4237828 2484.1.1.41 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › AnmK 0.57 47.0 3.41e-01 95.2% 37.4%
3242603 11.2.1.1 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain › C2 0.56 47.0 3.69e-01 92.1% 60.8%
3974494 330.1.1.34 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › DUF6348 0.56 43.0 3.80e-01 88.9% 55.8%
4365325 330.4.1.1 ↗ a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.56 41.0 3.74e-01 87.3% 58.8%
3507165 719.1.1.1 ↗ beta barrels › XRCC4, N-terminal domain-like › XRCC4, N-terminal domain › XRCC4, N-terminal domain › XRCC4 0.55 36.0 2.98e-01 93.7% 33.6%
3965662 264.2.1.1 ↗ beta barrels › LigT-like › Prokaryotic type I DNA topoisomerase beta-barrel domain › Prokaryotic type I DNA topoisomerase beta-barrel domain › Topoisom_bac 0.55 39.0 3.12e-01 76.2% 55.7%
3940510 2484.5.1.2 ↗ mixed a+b and a/b › Ribonuclease H-like › RNaseH-like domain in reverse transcriptase › RNaseH-like domain in reverse transcriptase › RT_RNaseH 0.55 44.0 4.10e-01 92.1% 70.0%
3935094 2484.5.1.3 ↗ mixed a+b and a/b › Ribonuclease H-like › RNaseH-like domain in reverse transcriptase › RNaseH-like domain in reverse transcriptase › RT_RNaseH_2 0.55 40.0 3.36e-01 90.5% 43.5%
3934889 2484.5.1.2 ↗ mixed a+b and a/b › Ribonuclease H-like › RNaseH-like domain in reverse transcriptase › RNaseH-like domain in reverse transcriptase › RT_RNaseH 0.55 44.0 3.56e-01 92.1% 44.8%
3924494 2484.5.1.2 ↗ mixed a+b and a/b › Ribonuclease H-like › RNaseH-like domain in reverse transcriptase › RNaseH-like domain in reverse transcriptase › RT_RNaseH 0.55 44.0 3.65e-01 92.1% 48.7%
3266323 216.1.1.4 ↗ a+b two layers › UBC-like › UBC-like › UBC-like › RWD 0.55 40.0 3.32e-01 79.4% 45.8%
3262383 2484.5.1.2 ↗ mixed a+b and a/b › Ribonuclease H-like › RNaseH-like domain in reverse transcriptase › RNaseH-like domain in reverse transcriptase › RT_RNaseH 0.55 43.0 3.42e-01 90.5% 40.7%
3927917 11.2.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain 0.55 44.0 3.31e-01 92.1% 49.7%
3888760 11.2.1.1 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain › C2 0.55 45.0 3.43e-01 92.1% 72.0%
3932481 2484.5.1.2 ↗ mixed a+b and a/b › Ribonuclease H-like › RNaseH-like domain in reverse transcriptase › RNaseH-like domain in reverse transcriptase › RT_RNaseH 0.54 41.0 3.34e-01 92.1% 40.8%
4012666 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.54 44.0 3.18e-01 93.7% 34.6%
3781730 5.1.11.3 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 9-bladed › Utp8_b_propeller 0.54 48.0 3.00e-01 100.0% 25.4%
3717506 5.1.3.0 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed 0.54 45.0 2.90e-01 100.0% 26.2%
3580101 11.2.1.1 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain › C2 0.54 45.0 3.34e-01 92.1% 81.0%
3260251 11.2.1.1 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain › C2 0.54 44.0 3.43e-01 92.1% 74.5%
3565886 11.2.1.1 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain › C2 0.54 44.0 3.41e-01 92.1% 73.1%
3616898 11.2.1.1 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain › C2 0.54 44.0 3.38e-01 92.1% 69.3%
4933424 2484.1.1.43 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Endonuclease_5 0.54 45.0 3.11e-01 92.1% 27.6%
3540845 11.2.1.1 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain › C2 0.54 44.0 3.43e-01 92.1% 54.3%
3933422 2484.5.1.2 ↗ mixed a+b and a/b › Ribonuclease H-like › RNaseH-like domain in reverse transcriptase › RNaseH-like domain in reverse transcriptase › RT_RNaseH 0.54 42.0 3.42e-01 92.1% 43.1%
3933536 2484.5.1.2 ↗ mixed a+b and a/b › Ribonuclease H-like › RNaseH-like domain in reverse transcriptase › RNaseH-like domain in reverse transcriptase › RT_RNaseH 0.53 42.0 3.38e-01 92.1% 41.5%
3393528 11.2.1.55 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain › C2_SYDE 0.53 44.0 3.33e-01 92.1% 48.4%
3926560 2484.1.1.212 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RT_RNaseH 0.53 42.0 3.36e-01 92.1% 41.5%
3933233 2484.5.1.2 ↗ mixed a+b and a/b › Ribonuclease H-like › RNaseH-like domain in reverse transcriptase › RNaseH-like domain in reverse transcriptase › RT_RNaseH 0.53 42.0 3.41e-01 92.1% 43.1%
3514675 11.2.1.1 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain › C2 0.53 44.0 3.64e-01 93.7% 63.5%
3173127 11.2.1.1 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain › C2 0.53 44.0 3.30e-01 92.1% 45.2%
3923656 2484.5.1.2 ↗ mixed a+b and a/b › Ribonuclease H-like › RNaseH-like domain in reverse transcriptase › RNaseH-like domain in reverse transcriptase › RT_RNaseH 0.53 41.0 3.30e-01 92.1% 40.0%
3791555 11.2.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain 0.53 43.0 3.44e-01 93.7% 56.3%
3229149 11.2.1.55 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain › C2_SYDE 0.52 43.0 3.40e-01 92.1% 71.1%
3825820 11.2.1.1 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain › C2 0.52 43.0 3.36e-01 92.1% 77.9%
3708379 5.1.5.208 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed › EMC1_C, PQQ_2, Beta-prop_EMC1_N 0.52 45.0 2.58e-01 100.0% 13.5%
5064795 264.2.1.1 ↗ beta barrels › LigT-like › Prokaryotic type I DNA topoisomerase beta-barrel domain › Prokaryotic type I DNA topoisomerase beta-barrel domain › Topoisom_bac 0.52 37.0 3.09e-01 77.8% 55.8%
2325425 2484.1.1.31 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Glucokinase 0.52 39.0 3.10e-01 88.9% 36.7%
4460237 330.4.1.1 ↗ a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.52 32.0 3.10e-01 93.7% 53.3%
5063764 2484.1.1.43 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Endonuclease_5 0.51 40.0 2.90e-01 90.5% 29.2%
3521189 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.51 40.0 3.44e-01 87.3% 62.9%
3209099 511.1.1.0 ↗ beta sandwiches › Heat shock protein 70kD (HSP70), peptide-binding domain › Heat shock protein 70kD (HSP70), peptide-binding domain › Heat shock protein 70kD (HSP70), peptide-binding domain 0.51 39.0 3.13e-01 90.5% 94.2%
3930501 2484.5.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › RNaseH-like domain in reverse transcriptase › RNaseH-like domain in reverse transcriptase 0.51 39.0 3.19e-01 92.1% 42.4%
3771405 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.51 40.0 2.98e-01 87.3% 39.4%
3326860 2484.1.1.67 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3 0.50 39.0 3.63e-01 88.9% 69.4%
3640946 11.2.1.1 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain › C2 0.50 41.0 3.21e-01 92.1% 53.6%
D6 medium residues 98-168_346-385
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00814.32 best TsaD 64.5 1.80e-17 68.5% 25.4%
CATH (44)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3zeuB01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.92 89.0 7.40e-01 100.0% 64.5%
2ivnA01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.91 86.0 7.28e-01 100.0% 64.9%
3wuhB01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.89 86.0 7.12e-01 100.0% 64.6%
1okjB01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.89 67.0 6.39e-01 99.1% 68.5%
3rotA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.67 47.0 4.41e-01 73.0% 91.2%
2hoeA02 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.66 53.0 4.80e-01 87.4% 70.9%
3bzcA03 3.30.420.140 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › YqgF/RNase H-like domain 0.65 50.0 4.81e-01 82.0% 75.0%
1e5xA01 3.40.50.1100 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.65 53.0 3.86e-01 86.5% 47.5%
4ep4A00 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.65 55.0 4.88e-01 94.6% 72.3%
1hjrA00 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.64 52.0 4.64e-01 87.4% 71.5%
3hzrA01 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.63 51.0 3.86e-01 86.5% 60.5%
3cs3A02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.63 44.0 4.14e-01 73.0% 91.3%
2odkA00 3.40.1620.10 Alpha Beta › 3-Layer(aba) Sandwich › YefM-like fold › YefM-like domain 0.62 26.0 3.58e-01 72.1% 80.0%
6gfaA01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.62 46.0 4.23e-01 79.3% 77.0%
6hcdD00 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.61 46.0 4.30e-01 83.8% 64.4%
3cisH00 3.40.50.12370 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.61 45.0 3.31e-01 76.6% 63.5%
5byvB01 3.40.47.10 Alpha Beta › 3-Layer(aba) Sandwich › Peroxisomal Thiolase; Chain A, domain 1 › Thiolase/Chalcone synthase 0.60 42.0 3.46e-01 86.5% 38.3%
4ijaB02 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.60 47.0 4.25e-01 84.7% 72.6%
3hs3A02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.60 42.0 3.94e-01 73.0% 78.3%
4bjhB02 3.40.50.1370 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Aspartate/ornithine carbamoyltransferase 0.60 42.0 3.90e-01 73.0% 98.6%
5hn3A00 3.40.718.10 Alpha Beta › 3-Layer(aba) Sandwich › Isopropylmalate Dehydrogenase › Isopropylmalate Dehydrogenase 0.60 43.0 3.07e-01 74.8% 31.6%
4kq9A02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.60 42.0 3.47e-01 73.0% 62.5%
7essA01 3.30.420.140 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › YqgF/RNase H-like domain 0.59 47.0 4.52e-01 88.3% 75.8%
1vwxG01 3.30.1330.30 Alpha Beta › 2-Layer Sandwich › 60s Ribosomal Protein L30; Chain: A; › Ribosomal protein L30/S12 0.59 47.0 3.98e-01 91.9% 51.4%
2aa4A01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.58 45.0 4.21e-01 82.0% 77.4%
7yosA01 3.90.1640.30 Alpha Beta › Alpha-Beta Complex › inorganic pyrophosphatase (n-terminal core) › 0.58 40.0 3.35e-01 70.3% 61.8%
1qp8A02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.58 41.0 3.48e-01 73.9% 74.6%
2xzmU00 3.30.1330.30 Alpha Beta › 2-Layer Sandwich › 60s Ribosomal Protein L30; Chain: A; › Ribosomal protein L30/S12 0.57 47.0 4.58e-01 91.0% 79.0%
4as2A01 3.40.50.1000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like 0.57 40.0 3.22e-01 73.0% 92.4%
3nohA00 3.40.190.210 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › 0.57 40.0 3.92e-01 73.0% 91.8%
2qjcA00 3.60.21.10 Alpha Beta › 4-Layer Sandwich › Purple Acid Phosphatase; chain A, domain 2 › Metallo-dependent phosphatases 0.56 42.0 3.37e-01 79.3% 84.7%
3rqtA02 3.10.105.10 Alpha Beta › Roll › Dipeptide-binding Protein; domain 3 › Dipeptide-binding Protein; Domain 3 0.56 39.0 3.23e-01 73.0% 76.1%
1yoeA00 3.90.245.10 Alpha Beta › Alpha-Beta Complex › Inosine-uridine Nucleoside N-ribohydrolase; Chain A › Ribonucleoside hydrolase-like 0.55 46.0 3.46e-01 94.6% 76.8%
2z3vA00 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.55 42.0 3.97e-01 82.9% 66.4%
2wvlB00 3.90.550.10 Alpha Beta › Alpha-Beta Complex › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A 0.54 45.0 3.13e-01 91.9% 83.2%
2iu4A01 3.40.50.10440 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Dihydroxyacetone kinase; domain 1 0.53 42.0 3.66e-01 87.4% 55.0%
4g2dA00 3.20.20.140 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Metal-dependent hydrolases 0.53 44.0 3.22e-01 90.1% 66.6%
1edzA02 3.40.50.10860 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Leucine Dehydrogenase, chain A, domain 1 0.52 38.0 3.59e-01 74.8% 80.2%
1zzmA00 3.20.20.140 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Metal-dependent hydrolases 0.52 43.0 3.26e-01 88.3% 71.0%
3p8kA00 3.60.110.10 Alpha Beta › 4-Layer Sandwich › Nitrilase/N-carbamoyl-D-aminoacid amidohydrolase › Carbon-nitrogen hydrolase 0.52 40.0 3.09e-01 83.8% 84.7%
2a1fC00 3.40.1160.10 Alpha Beta › 3-Layer(aba) Sandwich › Carbamate kinase › Acetylglutamate kinase-like 0.52 37.0 2.95e-01 73.9% 79.7%
2btoA01 3.40.50.1440 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Tubulin/FtsZ, GTPase domain 0.51 44.0 3.40e-01 95.5% 57.3%
3s3tA00 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.51 37.0 3.44e-01 76.6% 84.8%
1jpdX02 3.20.20.120 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Enolase-like C-terminal domain 0.51 33.0 2.67e-01 96.4% 34.8%
ECOD (43)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3528343 2484.1.1.10 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › TsaD 0.95 72.0 6.55e-01 100.0% 61.4%
4497115 2484.1.1.10 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › TsaD 0.94 86.0 7.16e-01 100.0% 60.0%
3584677 2484.1.1.10 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › TsaD 0.93 67.0 6.32e-01 100.0% 63.1%
4652229 2484.1.1.10 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › TsaD 0.93 70.0 6.25e-01 100.0% 58.1%
4304382 2484.1.1.10 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › TsaD 0.93 85.0 7.00e-01 100.0% 58.3%
4376497 2484.1.1.10 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › TsaD 0.93 88.0 7.30e-01 100.0% 62.3%
4107626 2484.1.1.10 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › TsaD 0.93 73.0 6.37e-01 100.0% 58.1%
4600904 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.93 85.0 7.01e-01 100.0% 58.9%
3302384 2484.1.1.10 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › TsaD 0.92 67.0 5.96e-01 100.0% 55.3%
4133401 2484.1.1.10 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › TsaD 0.92 89.0 5.96e-01 100.0% 80.0%
4539019 2484.1.1.10 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › TsaD 0.92 89.0 7.22e-01 100.0% 60.0%
4107955 2484.1.1.10 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › TsaD 0.92 89.0 6.01e-01 100.0% 83.6%
None — 0.92 89.0 6.01e-01 100.0% 81.8%
4575901 2484.1.1.10 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › TsaD 0.91 88.0 5.88e-01 100.0% 82.3%
4344890 2484.1.1.10 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › TsaD 0.91 88.0 5.83e-01 100.0% 79.2%
3800825 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.91 87.0 7.32e-01 100.0% 64.7%
4668814 2484.1.1.10 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › TsaD 0.91 66.0 5.55e-01 100.0% 48.0%
3432179 2484.1.1.10 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › TsaD 0.91 87.0 5.87e-01 100.0% 78.0%
4467784 2484.1.1.10 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › TsaD 0.90 71.0 6.19e-01 100.0% 58.1%
5030386 2484.1.1.10 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › TsaD 0.90 83.0 7.09e-01 100.0% 64.8%
3166896 2484.1.1.10 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › TsaD 0.90 86.0 5.70e-01 100.0% 80.8%
4600109 2484.1.1.10 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › TsaD 0.89 67.0 6.12e-01 100.0% 61.4%
4233313 2484.1.1.10 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › TsaD 0.88 82.0 7.07e-01 97.3% 68.1%
3320988 2484.1.1.10 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › TsaD 0.86 67.0 5.78e-01 100.0% 55.6%
4443917 2484.1.1.10 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › TsaD 0.81 68.0 6.00e-01 100.0% 64.0%
3951299 2484.1.1.10 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › TsaD 0.76 70.0 5.68e-01 97.3% 78.5%
3636281 2484.1.1.10 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › TsaD 0.70 67.0 5.36e-01 100.0% 58.5%
3681631 2484.1.1.40 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RuvX 0.68 58.0 4.92e-01 92.8% 62.8%
3960090 2484.1.1.216 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DUF7159 0.67 54.0 4.51e-01 87.4% 93.3%
4108829 2484.1.1.144 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DEDD_Tnp_IS110 0.66 50.0 4.95e-01 89.2% 75.0%
3954516 2484.1.1.144 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DEDD_Tnp_IS110 0.65 50.0 4.87e-01 93.7% 75.0%
4355370 2484.1.1.40 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RuvX 0.65 54.0 4.95e-01 91.0% 71.7%
3707575 2484.1.1.74 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Tex_YqgF 0.62 52.0 4.63e-01 92.8% 71.9%
4853117 2484.1.1.10 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › TsaD 0.60 40.0 4.08e-01 100.0% 69.4%
3956789 2484.1.1.144 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DEDD_Tnp_IS110 0.58 51.0 4.63e-01 96.4% 80.0%
4678704 2005.1.1.11 ↗ a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › ATP_bind_3 0.58 46.0 3.60e-01 85.6% 40.0%
2410577 2005.1.1.31 ↗ a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › CDPS 0.57 44.0 3.60e-01 83.8% 81.8%
3769836 2006.1.6.1 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA 0.57 41.0 3.26e-01 86.5% 37.7%
3385824 2005.1.1.0 ↗ a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains 0.56 41.0 4.04e-01 76.6% 77.5%
5044019 2005.1.1.0 ↗ a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains 0.55 43.0 3.33e-01 84.7% 36.5%
4093291 2007.1.6.2 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Aminoacid dehydrogenase-like, N-terminal domain › THF_DHG_CYH 0.52 36.0 3.73e-01 71.2% 92.4%
3278371 2005.1.1.3 ↗ a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › Usp 0.51 37.0 3.40e-01 76.6% 81.3%
5029051 2002.1.1.44 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › TatD_DNase 0.50 42.0 3.23e-01 89.2% 71.0%