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Threonylcarbamoyl_AMP_synthase

Euk-Vir

Pandoravirus_salinus

Threonylcarbamoyl_AMP_synthase__YP_009430141__Pandoravirus_salinus__1349410

Identity

Accession:
YP_009430141 ↗
Protein ID:
Threonylcarbamoyl_AMP_synthase
Kingdom:
euk

Quality

86.2 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 40-168_346-386
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00814.32 best TsaD 81.3 1.40e-22 58.8% 36.4%
D2 high residues 206-341
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00814.32 best TsaD 42.2 1.20e-10 99.3% 38.6%
CATH (23)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2ivnA02 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.91 79.0 7.50e-01 100.0% 78.3%
3zeuB02 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.88 81.0 7.46e-01 100.0% 78.8%
3wuhA02 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.81 75.0 6.89e-01 100.0% 79.2%
7vyjB01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.78 74.0 6.53e-01 100.0% 75.8%
3ttcA04 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.75 65.0 5.29e-01 100.0% 50.4%
6jdbA02 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.75 50.0 4.81e-01 100.0% 60.1%
4qs8A01 3.40.367.20 Alpha Beta › 3-Layer(aba) Sandwich › Hexokinase; domain 1 › 0.74 52.0 4.07e-01 72.1% 96.8%
2itmB02 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.70 56.0 4.64e-01 100.0% 48.7%
4bgbA02 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.70 62.0 5.61e-01 100.0% 70.3%
1huxA02 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.70 52.0 5.15e-01 100.0% 74.3%
2f9wA02 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.68 45.0 4.77e-01 100.0% 76.3%
3h1qA02 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.67 42.0 4.56e-01 100.0% 74.8%
3gg4A02 1.20.58.2240 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.66 61.0 5.59e-01 100.0% 80.7%
3ll3B02 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.64 54.0 4.45e-01 100.0% 50.6%
3i8bA02 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.64 53.0 4.50e-01 100.0% 54.2%
2f07B00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.56 39.0 3.44e-01 70.6% 77.0%
2xq2A01 1.20.1730.10 Mainly Alpha › Up-down Bundle › Sodium/glucose cotransporter › Sodium/glucose cotransporter 0.54 43.0 2.88e-01 84.6% 48.2%
1dnpA01 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.53 35.0 3.63e-01 100.0% 70.0%
4gc0A01 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.51 41.0 3.41e-01 86.0% 61.4%
7zh0A01 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.51 45.0 3.27e-01 97.1% 78.8%
1qmgA02 1.10.1040.10 Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 0.51 37.0 2.91e-01 75.7% 95.9%
7vwtA01 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.51 36.0 2.74e-01 72.8% 82.9%
5ziyA01 1.20.1330.10 Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain 0.50 37.0 3.32e-01 77.2% 76.3%
ECOD (39)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3466452 2484.1.1.10 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › TsaD 0.90 87.0 6.77e-01 100.0% 57.7%
4616268 2484.1.1.10 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › TsaD 0.90 81.0 7.10e-01 100.0% 67.4%
3416550 2484.1.1.10 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › TsaD 0.90 86.0 6.66e-01 100.0% 58.9%
3937876 2484.1.1.10 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › TsaD 0.89 85.0 6.80e-01 100.0% 58.8%
4029485 2484.1.1.10 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › TsaD 0.88 84.0 5.66e-01 100.0% 35.7%
4358375 2484.1.1.10 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › TsaD 0.88 84.0 6.85e-01 100.0% 59.1%
3217430 2484.1.1.10 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › TsaD 0.88 84.0 6.58e-01 100.0% 56.9%
4128947 2484.1.1.10 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › TsaD 0.87 83.0 6.78e-01 100.0% 61.4%
3974538 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.86 82.0 6.80e-01 100.0% 62.3%
4089762 2484.1.1.10 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › TsaD 0.85 80.0 6.66e-01 100.0% 61.9%
3689247 2484.1.1.10 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › TsaD 0.84 80.0 6.29e-01 100.0% 65.8%
4504181 2484.1.1.10 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › TsaD 0.84 80.0 6.96e-01 100.0% 69.7%
4107955 2484.1.1.10 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › TsaD 0.84 78.0 5.66e-01 100.0% 39.7%
3166896 2484.1.1.10 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › TsaD 0.84 79.0 5.57e-01 100.0% 41.3%
3724786 2484.1.1.41 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › AnmK 0.72 65.0 5.61e-01 100.0% 63.3%
4980794 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.72 65.0 5.32e-01 100.0% 54.3%
4303037 2484.1.1.41 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › AnmK 0.71 64.0 5.85e-01 100.0% 73.9%
4101540 2484.1.1.41 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › AnmK 0.70 62.0 5.26e-01 100.0% 59.5%
4054263 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.68 62.0 5.12e-01 100.0% 56.2%
4967139 2484.1.1.137 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DUF2114 0.67 60.0 4.28e-01 100.0% 33.1%
3948016 2484.1.1.32 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › FGGY_C 0.66 60.0 4.80e-01 100.0% 54.0%
3967012 2484.1.1.32 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › FGGY_C 0.64 54.0 4.49e-01 100.0% 51.9%
3714252 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.62 48.0 3.84e-01 80.9% 72.8%
3592428 192.7.1.0 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm 0.61 39.0 3.83e-01 77.2% 60.0%
4471187 3236.2.1.11 alpha complex topology › Cation-proton antiporter › Sodium-dependent citrate symporter › Sodium-dependent citrate symporter › Cons_hypoth698 0.61 48.0 3.65e-01 84.6% 67.0%
11180 2484.1.1.70 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › FtsA 0.61 49.0 4.41e-01 100.0% 62.7%
3733618 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.60 54.0 4.71e-01 100.0% 66.2%
3838712 2484.1.1.245 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › SHS2_FTSA, PilM_2, FtsA 0.60 50.0 3.49e-01 100.0% 28.8%
3188923 2484.1.1.220 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › PF27033 0.58 54.0 4.44e-01 100.0% 69.8%
3689980 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.57 53.0 4.45e-01 100.0% 71.4%
4963441 2484.1.1.340 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Volactin 0.55 49.0 4.36e-01 100.0% 70.3%
3693411 5069.1.1.4 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Ferric_reduct 0.54 47.0 3.88e-01 91.2% 71.3%
4626183 5051.1.1.2 alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › AA_permease 0.54 44.0 3.07e-01 86.8% 54.8%
3252505 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.53 47.0 3.29e-01 98.5% 91.5%
3847309 2484.1.1.1 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › HSP70 0.52 47.0 4.06e-01 100.0% 62.9%
3783691 2484.1.1.1 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › HSP70 0.51 46.0 3.98e-01 100.0% 63.3%
3690688 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.51 42.0 3.75e-01 88.2% 70.3%
3945884 2484.1.1.1 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › HSP70 0.51 47.0 3.82e-01 100.0% 73.1%
3732773 2484.1.1.220 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › PF27033 0.51 44.0 3.86e-01 100.0% 62.9%
D3 high residues 391-610
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF01300.25 best Sua5_yciO_yrdC 164.2 3.00e-48 82.7% 99.4%
D4 high residues 645-750
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF03481.20 best Sua5_C 41.4 2.90e-10 94.3% 60.0%
D5 high residues 774-1006
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00899.28 best ThiF 113.3 1.50e-32 99.1% 77.7%