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Threonylcarbamoyl_AMP_synthase

Euk-Vir

Pandoravirus_macleodensis

Threonylcarbamoyl_AMP_synthase__YP_009481386__Pandoravirus_macleodensis__2107707

Identity

Accession:
YP_009481386 ↗
Protein ID:
Threonylcarbamoyl_AMP_synthase
Kingdom:
euk

Quality

86.7 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 40-170_345-377
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00814.32 best TsaD 79.7 4.20e-22 69.5% 39.4%
D2 high residues 410-613
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF01300.25 best Sua5_yciO_yrdC 168.6 1.30e-49 90.2% 99.4%
D3 high residues 648-752
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF03481.20 best Sua5_C 45.0 2.40e-11 94.3% 60.8%
D4 high residues 764-1002
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00899.28 best ThiF 112.0 3.70e-32 96.7% 72.3%
D5 medium residues 171-243_306-319_333-343
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00814.32 best TsaD 43.4 4.90e-11 88.8% 23.1%
CATH (19)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3wuhA02 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.85 79.0 6.44e-01 98.0% 98.8%
3zeuB02 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.81 76.0 6.21e-01 98.0% 98.8%
2ivnA02 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.79 74.0 6.14e-01 99.0% 98.7%
5ly3A02 3.30.420.570 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › 0.70 64.0 4.85e-01 100.0% 98.2%
2i7nA02 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.67 61.0 5.23e-01 100.0% 80.6%
2zgyA02 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.65 58.0 5.16e-01 99.0% 99.3%
2fsjA02 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.61 54.0 4.86e-01 100.0% 100.0%
3js6A02 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.57 51.0 4.81e-01 100.0% 98.3%
1nbwA04 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.57 50.0 4.58e-01 100.0% 98.5%
3c0bA02 3.30.420.190 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › conserved archaeal protein q6m145 0.57 50.0 3.90e-01 100.0% 79.5%
3h6eB01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.56 49.0 4.94e-01 99.0% 94.9%
4bg8A01 3.30.420.430 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › 0.55 50.0 4.54e-01 100.0% 75.2%
4o5fA01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.54 41.0 3.69e-01 100.0% 58.8%
3hz6A01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.54 49.0 3.61e-01 99.0% 93.6%
6m90A02 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.53 36.0 2.64e-01 70.4% 63.1%
1u6zA02 3.30.420.150 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Exopolyphosphatase. Domain 2 0.53 47.0 3.92e-01 100.0% 87.2%
3sc7X01 2.115.10.20 Mainly Beta › 5 Propeller › Tachylectin-2; Chain A › Glycosyl hydrolase domain; family 43 0.52 36.0 2.59e-01 74.5% 71.4%
3bexA01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.51 42.0 3.73e-01 100.0% 62.5%
3hrgA02 3.30.420.260 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Protein of unknown function DUF3822, C-terminal domain 0.51 40.0 3.84e-01 100.0% 72.8%
ECOD (50)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3476736 2484.1.1.10 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › TsaD 0.91 88.0 6.09e-01 100.0% 72.0%
3416550 2484.1.1.10 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › TsaD 0.90 87.0 6.07e-01 100.0% 72.1%
3466452 2484.1.1.10 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › TsaD 0.90 87.0 6.09e-01 100.0% 71.2%
3994856 2484.1.1.10 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › TsaD 0.90 85.0 6.17e-01 98.0% 77.8%
3937876 2484.1.1.10 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › TsaD 0.90 86.0 6.14e-01 100.0% 73.1%
3217430 2484.1.1.10 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › TsaD 0.89 83.0 5.89e-01 98.0% 69.8%
3743477 2484.1.1.10 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › TsaD 0.89 85.0 6.11e-01 100.0% 76.7%
4358375 2484.1.1.10 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › TsaD 0.88 85.0 6.18e-01 100.0% 74.3%
3784275 2484.1.1.10 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › TsaD 0.88 84.0 5.92e-01 100.0% 77.3%
4616123 2484.1.1.10 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › TsaD 0.88 60.0 4.42e-01 74.5% 30.0%
3184351 2484.1.1.10 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › TsaD 0.88 83.0 5.75e-01 100.0% 85.6%
3208119 2484.1.1.10 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › TsaD 0.88 84.0 5.75e-01 100.0% 81.0%
3166896 2484.1.1.10 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › TsaD 0.87 82.0 5.33e-01 100.0% 50.7%
4128947 2484.1.1.10 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › TsaD 0.87 83.0 6.06e-01 100.0% 79.8%
3689247 2484.1.1.10 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › TsaD 0.86 82.0 5.82e-01 100.0% 79.2%
4391331 2484.1.1.10 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › TsaD 0.84 81.0 6.05e-01 100.0% 78.6%
3974538 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.84 80.0 5.97e-01 100.0% 78.6%
None 0.83 79.0 5.84e-01 100.0% 80.9%
4853039 2484.1.1.10 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › TsaD 0.83 59.0 6.76e-01 73.5% 98.6%
4089762 2484.1.1.10 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › TsaD 0.83 79.0 5.89e-01 100.0% 78.1%
4492619 2484.1.1.10 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › TsaD 0.83 79.0 5.94e-01 100.0% 79.4%
4575901 2484.1.1.10 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › TsaD 0.82 79.0 5.14e-01 100.0% 50.4%
4371758 2484.1.1.10 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › TsaD 0.82 79.0 5.84e-01 100.0% 75.7%
None 0.82 78.0 5.19e-01 100.0% 49.0%
4133401 2484.1.1.10 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › TsaD 0.82 78.0 5.12e-01 100.0% 48.5%
4107955 2484.1.1.10 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › TsaD 0.82 78.0 5.18e-01 100.0% 50.1%
4616268 2484.1.1.10 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › TsaD 0.82 78.0 6.06e-01 100.0% 85.8%
4370096 2484.1.1.10 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › TsaD 0.82 77.0 5.78e-01 100.0% 78.0%
4555445 2484.1.1.10 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › TsaD 0.82 77.0 5.73e-01 100.0% 76.4%
4060448 2484.1.1.10 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › TsaD 0.81 76.0 5.57e-01 100.0% 76.7%
4303479 2484.1.1.10 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › TsaD 0.81 77.0 5.76e-01 100.0% 79.1%
4504181 2484.1.1.10 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › TsaD 0.81 76.0 5.89e-01 100.0% 87.7%
4621629 2484.1.1.10 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › TsaD 0.80 75.0 5.51e-01 100.0% 75.1%
4113840 2484.1.1.10 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › TsaD 0.78 75.0 5.74e-01 100.0% 82.1%
3169550 2484.1.1.39 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Fumble 0.70 64.0 4.75e-01 100.0% 78.4%
4981065 2484.1.1.21 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › BcrAD_BadFG 0.67 61.0 4.99e-01 100.0% 83.4%
4418050 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.65 59.0 3.93e-01 100.0% 39.0%
5005743 2484.1.1.87 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › MreB-like_C 0.64 57.0 4.67e-01 99.0% 78.4%
4945490 2484.1.1.334 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DUF1786 0.62 55.0 3.72e-01 99.0% 60.6%
11196 2484.1.1.56 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDR 0.61 55.0 4.35e-01 100.0% 86.2%
3947630 2484.1.1.56 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDR 0.60 53.0 3.47e-01 100.0% 39.3%
4257154 220.1.1.126 beta barrels › PH domain-like › PH domain-like › PH domain-like › Ycf4 0.58 33.0 3.27e-01 87.8% 51.9%
4953954 2484.1.1.334 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DUF1786 0.58 51.0 3.53e-01 99.0% 60.3%
3213163 2484.1.1.162 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › F-box 0.56 43.0 3.91e-01 99.0% 61.5%
4144852 220.1.1.126 beta barrels › PH domain-like › PH domain-like › PH domain-like › Ycf4 0.55 34.0 3.35e-01 99.0% 56.5%
3967001 2484.1.1.6 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › FGGY_N 0.54 47.0 3.63e-01 99.0% 93.6%
3949916 2484.1.1.29 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Ppx-GppA 0.53 47.0 3.82e-01 100.0% 88.4%
3206461 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.53 46.0 3.44e-01 99.0% 94.0%
3196233 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.52 45.0 3.89e-01 98.0% 86.5%
4021862 7575.1.1.9 a/b three-layered sandwiches › Caspase-like › Caspase-like › Caspase-like › CHAT 0.50 44.0 3.07e-01 100.0% 33.3%
D6 medium residues 244-305_320-332
PDB
Domain cluster: representative
ECOD (1)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3929397 5048.1.1.1 alpha complex topology › Aquaporin-like › Aquaporin-like › Aquaporin-like › MIP 0.61 53.0 3.80e-01 97.3% 83.5%