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Thymidine_kinase
Euk-VirAfrican_swine_fever_virus
Thymidine_kinase__YP_009703106__African_swine_fever_virus__10497
Identity
- Accession:
- YP_009703106 ↗
- Protein ID:
- Thymidine_kinase
- Kingdom:
- euk
Quality
84.8
mean pLDDT
Taxonomy
Bamfordvirae›
Nucleocytoviricota›
Pokkesviricetes›
Asfuvirales›
Asfarviridae›
Asfivirus›
African_swine_fever_virus
TaxID: 10497
Cluster
View cluster (85 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 3-141
Domain cluster:
rep: NC_021330__YP_008059651.1__M202-gp129__00089__D21-171
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00265.25 best | TK | 150.7 | 5.30e-44 | 95.0% | 76.1% |
D2
high
residues 144-190
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00265.25 best | TK | 42.7 | 8.00e-11 | 85.1% | 21.6% |
CATH (11)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1w4rA02 | 3.30.60.20 | Alpha Beta › 2-Layer Sandwich › Wheat Germ Agglutinin (Isolectin 2); domain 1 › | 0.94 | 77.0 | 8.12e-01 | 89.4% | 97.6% |
| 4e1pA00 | 3.30.60.230 | Alpha Beta › 2-Layer Sandwich › Wheat Germ Agglutinin (Isolectin 2); domain 1 › Lsr2, dimerisation domain | 0.75 | 61.0 | 5.74e-01 | 100.0% | 74.5% |
| 3m7kA00 | 3.30.40.220 | Alpha Beta › 2-Layer Sandwich › Herpes Virus-1 › | 0.68 | 59.0 | 4.20e-01 | 100.0% | 41.5% |
| 2qgpA00 | 1.10.30.50 | Mainly Alpha › Orthogonal Bundle › DNA Binding (I), subunit A › | 0.66 | 56.0 | 4.75e-01 | 100.0% | 57.8% |
| 3jyuB01 | 3.30.2230.10 | Alpha Beta › 2-Layer Sandwich › DUSP-like › DUSP-like | 0.64 | 48.0 | 3.72e-01 | 91.5% | 70.9% |
| 7po9A01 | 3.40.1800.20 | Alpha Beta › 3-Layer(aba) Sandwich › His-Me finger endonuclease fold › | 0.55 | 46.0 | 3.89e-01 | 100.0% | 70.9% |
| 1b3tA00 | 3.30.70.390 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Epstein Barr virus nuclear antigen-1, DNA-binding domain | 0.54 | 41.0 | 2.98e-01 | 89.4% | 57.8% |
| 3v4mB00 | 3.30.70.330 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain | 0.53 | 37.0 | 2.96e-01 | 76.6% | 73.1% |
| 3r5tA02 | 3.40.50.1980 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nitrogenase molybdenum iron protein domain | 0.52 | 37.0 | 2.57e-01 | 80.9% | 30.8% |
| 3jc6C00 | 1.20.58.2050 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.50 | 37.0 | 2.63e-01 | 83.0% | 29.6% |
| 2e9xB01 | 3.40.5.50 | Alpha Beta › 3-Layer(aba) Sandwich › Ribosomal Protein L9; domain 1 › | 0.50 | 37.0 | 3.38e-01 | 80.9% | 68.2% |
ECOD (24)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3362574 | 377.1.1.3 ↗ | few secondary structure elements › Glucocorticoid receptor-like › LIM domain-like › LIM domain-like › TK | 0.93 | 74.0 | 7.95e-01 | 87.2% | 100.0% |
| 3717094 | 2004.1.1.28 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › TK | 0.93 | 86.0 | 5.31e-01 | 100.0% | 21.3% |
| 1868224 | 377.1.1.3 ↗ | few secondary structure elements › Glucocorticoid receptor-like › LIM domain-like › LIM domain-like › TK | 0.92 | 85.0 | 7.72e-01 | 100.0% | 77.0% |
| 3674153 | 2004.1.1.28 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › TK | 0.90 | 83.0 | 5.16e-01 | 100.0% | 21.4% |
| 1636870 | 377.1.1.3 ↗ | few secondary structure elements › Glucocorticoid receptor-like › LIM domain-like › LIM domain-like › TK | 0.90 | 79.0 | 8.02e-01 | 97.9% | 97.8% |
| 4517886 | 377.1.1.3 ↗ | few secondary structure elements › Glucocorticoid receptor-like › LIM domain-like › LIM domain-like › TK | 0.89 | 79.0 | 8.07e-01 | 97.9% | 100.0% |
| 3588905 | 377.1.1.3 ↗ | few secondary structure elements › Glucocorticoid receptor-like › LIM domain-like › LIM domain-like › TK | 0.83 | 71.0 | 6.94e-01 | 93.6% | 96.0% |
| 4074154 | 377.1.1.3 ↗ | few secondary structure elements › Glucocorticoid receptor-like › LIM domain-like › LIM domain-like › TK | 0.82 | 66.0 | 6.78e-01 | 87.2% | 100.0% |
| 4675823 | 377.1.1.3 ↗ | few secondary structure elements › Glucocorticoid receptor-like › LIM domain-like › LIM domain-like › TK | 0.82 | 75.0 | 6.69e-01 | 100.0% | 78.5% |
| 4007998 | 2004.1.1.28 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › TK | 0.82 | 75.0 | 4.79e-01 | 100.0% | 24.9% |
| 4081305 | 2004.1.1.28 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › TK | 0.82 | 70.0 | 4.56e-01 | 100.0% | 23.2% |
| 5058383 | 377.1.1.3 ↗ | few secondary structure elements › Glucocorticoid receptor-like › LIM domain-like › LIM domain-like › TK | 0.82 | 73.0 | 7.16e-01 | 97.9% | 98.0% |
| 4355340 | 377.1.1.0 ↗ | few secondary structure elements › Glucocorticoid receptor-like › LIM domain-like › LIM domain-like | 0.81 | 73.0 | 6.93e-01 | 100.0% | 96.4% |
| 4462630 | 2004.1.1.28 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › TK | 0.79 | 71.0 | 4.56e-01 | 100.0% | 24.0% |
| 163182 | 377.1.1.3 ↗ | few secondary structure elements › Glucocorticoid receptor-like › LIM domain-like › LIM domain-like › TK | 0.78 | 69.0 | 6.79e-01 | 100.0% | 96.1% |
| 5060915 | 378.1.1.2 ↗ | few secondary structure elements › His-Me finger endonucleases › His-Me finger endonucleases › His-Me finger endonucleases › HNH | 0.76 | 67.0 | 5.74e-01 | 100.0% | 68.0% |
| 5017772 | 378.1.1.2 ↗ | few secondary structure elements › His-Me finger endonucleases › His-Me finger endonucleases › His-Me finger endonucleases › HNH | 0.73 | 65.0 | 5.07e-01 | 100.0% | 60.0% |
| 4964156 | 378.1.1.9 ↗ | few secondary structure elements › His-Me finger endonucleases › His-Me finger endonucleases › His-Me finger endonucleases › HNH_2 | 0.73 | 64.0 | 4.81e-01 | 100.0% | 85.2% |
| 1144783 | 378.1.1.2 ↗ | few secondary structure elements › His-Me finger endonucleases › His-Me finger endonucleases › His-Me finger endonucleases › HNH | 0.69 | 60.0 | 4.16e-01 | 100.0% | 30.6% |
| 3642367 | 377.1.1.0 ↗ | few secondary structure elements › Glucocorticoid receptor-like › LIM domain-like › LIM domain-like | 0.60 | 50.0 | 5.11e-01 | 91.5% | 97.8% |
| 3408969 | 377.9.1.8 ↗ | few secondary structure elements › Glucocorticoid receptor-like › HIT/MYND zinc finger-like › HIT/MYND zinc finger-like › zf-FCS | 0.59 | 44.0 | 3.96e-01 | 100.0% | 57.1% |
| 2831825 | 3167.1.1.1 ↗ | a+b two layers › 40S ribosomal protein rpS21 (S21e) › 40S ribosomal protein rpS21 (S21e) › 40S ribosomal protein rpS21 (S21e) › Ribosomal_S21e | 0.54 | 44.0 | 3.92e-01 | 93.6% | 75.0% |
| 3798304 | 376.1.3.0 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › FYVE/PHD zinc finger | 0.51 | 41.0 | 3.20e-01 | 100.0% | 52.8% |
| 3196317 | 4.8.1.1 ↗ | beta barrels › SH3 › Chromo domain-like › Chromo domain-like › Chromo | 0.50 | 35.0 | 2.60e-01 | 80.9% | 27.5% |