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Toll-like_receptor
Euk-VirChrysochromulina_ericina_virus
Toll-like_receptor__YP_009173511__Chrysochromulina_ericina_virus__455364
Identity
- Accession:
- YP_009173511 ↗
- Protein ID:
- Toll-like_receptor
- Kingdom:
- euk
Quality
77.7
mean pLDDT
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 4-153
Domain cluster:
rep: MK416008.1__QBP08155.1__X__00043__D161-291
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF13676.12 best | TIR_2 | 54.4 | 2.50e-14 | 94.7% | 89.3% |
| PF01582.26 | TIR | 22.0 | 1.80e-04 | 84.7% | 49.2% |
CATH (73)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5forA00 | 3.40.50.10140 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Toll/interleukin-1 receptor homology (TIR) domain | 0.75 | 63.0 | 6.68e-01 | 100.0% | 99.3% |
| 1fyvA00 | 3.40.50.10140 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Toll/interleukin-1 receptor homology (TIR) domain | 0.74 | 67.0 | 6.59e-01 | 100.0% | 88.8% |
| 4c6sA00 | 3.40.50.10140 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Toll/interleukin-1 receptor homology (TIR) domain | 0.74 | 65.0 | 6.66e-01 | 100.0% | 97.2% |
| 4c6rA00 | 3.40.50.10140 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Toll/interleukin-1 receptor homology (TIR) domain | 0.72 | 68.0 | 6.64e-01 | 100.0% | 98.1% |
| 2cxxA00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.72 | 66.0 | 6.14e-01 | 100.0% | 100.0% |
| 3h16B00 | 3.40.50.10140 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Toll/interleukin-1 receptor homology (TIR) domain | 0.71 | 59.0 | 6.21e-01 | 100.0% | 96.4% |
| 2q5cA01 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.67 | 40.0 | 4.90e-01 | 100.0% | 91.8% |
| 2pq6A01 | 3.40.50.2000 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; | 0.67 | 63.0 | 5.44e-01 | 100.0% | 98.2% |
| 3drwB01 | 3.40.1190.20 | Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase | 0.66 | 61.0 | 4.69e-01 | 100.0% | 96.7% |
| 3l6uA01 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.66 | 49.0 | 5.27e-01 | 100.0% | 90.5% |
| 3s28A03 | 3.40.50.2000 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; | 0.66 | 60.0 | 4.76e-01 | 100.0% | 87.1% |
| 4nqrA02 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.66 | 51.0 | 5.05e-01 | 94.7% | 77.4% |
| 4relA01 | 3.40.50.2000 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; | 0.65 | 61.0 | 4.95e-01 | 100.0% | 98.1% |
| 3fniA00 | 3.40.50.360 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Flavodoxin domain | 0.65 | 58.0 | 5.78e-01 | 100.0% | 92.9% |
| 1ba2A01 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.65 | 49.0 | 5.27e-01 | 100.0% | 94.4% |
| 2pv7A01 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.65 | 53.0 | 5.27e-01 | 98.7% | 82.4% |
| 3f2vA00 | 3.40.50.360 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Flavodoxin domain | 0.65 | 59.0 | 5.65e-01 | 100.0% | 100.0% |
| 2btoA01 | 3.40.50.1440 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Tubulin/FtsZ, GTPase domain | 0.64 | 59.0 | 4.90e-01 | 100.0% | 93.1% |
| 3h5oA01 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.64 | 48.0 | 5.12e-01 | 100.0% | 90.6% |
| 4l22A01 | 3.40.50.2000 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; | 0.64 | 58.0 | 4.22e-01 | 100.0% | 89.6% |
| 3bilA01 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.64 | 47.0 | 5.20e-01 | 100.0% | 95.8% |
| 6wb4B01 | 3.40.1190.20 | Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase | 0.64 | 59.0 | 4.63e-01 | 100.0% | 84.6% |
| 1xoiA01 | 3.40.50.2000 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; | 0.64 | 58.0 | 4.07e-01 | 100.0% | 86.3% |
| 3phhA02 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.63 | 48.0 | 5.17e-01 | 92.0% | 91.5% |
| 7kdyB01 | 3.40.50.280 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Cobalamin-binding domain | 0.63 | 53.0 | 5.34e-01 | 100.0% | 88.8% |
| 4p98A01 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.63 | 49.0 | 5.04e-01 | 100.0% | 85.4% |
| 6kj0A01 | 3.40.50.1700 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycoside hydrolase family 3 C-terminal domain | 0.63 | 57.0 | 4.99e-01 | 97.3% | 80.1% |
| 2x41A02 | 3.40.50.1700 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycoside hydrolase family 3 C-terminal domain | 0.63 | 58.0 | 4.68e-01 | 99.3% | 88.1% |
| 4rkrB01 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.63 | 46.0 | 4.94e-01 | 100.0% | 87.7% |
| 4w4tB00 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.63 | 57.0 | 4.24e-01 | 100.0% | 63.2% |
| 6jmgB01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.63 | 58.0 | 5.55e-01 | 100.0% | 96.0% |
| 3c3kB01 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.63 | 47.0 | 4.93e-01 | 100.0% | 87.3% |
| 3tb6A01 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.62 | 49.0 | 5.08e-01 | 100.0% | 89.9% |
| 3kljA02 | 3.50.50.60 | Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain | 0.62 | 42.0 | 4.82e-01 | 87.3% | 94.5% |
| 4qqrB00 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.62 | 57.0 | 4.68e-01 | 100.0% | 72.8% |
| 2pk3A01 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.62 | 57.0 | 4.99e-01 | 100.0% | 86.8% |
| 4rk0D01 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.62 | 48.0 | 5.02e-01 | 100.0% | 90.4% |
| 2waaA02 | 3.40.50.1110 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SGNH hydrolase | 0.62 | 56.0 | 5.02e-01 | 100.0% | 97.6% |
| 3lftB02 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.61 | 46.0 | 4.73e-01 | 99.3% | 81.0% |
| 2c83A01 | 3.40.50.11120 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Sialyltransferase, N-terminal GT-B Rossman nucleotide-binding domain | 0.60 | 52.0 | 4.64e-01 | 92.0% | 98.1% |
| 3p94A00 | 3.40.50.1110 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SGNH hydrolase | 0.60 | 55.0 | 4.99e-01 | 100.0% | 88.7% |
| 4xr9B01 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.60 | 55.0 | 4.88e-01 | 98.7% | 89.6% |
| 1cvrA02 | 3.40.50.1460 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.60 | 54.0 | 4.73e-01 | 100.0% | 90.0% |
| 2iksA01 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.59 | 37.0 | 4.51e-01 | 84.0% | 97.9% |
| 3tauA01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.59 | 44.0 | 4.62e-01 | 100.0% | 86.5% |
| 3vpaB00 | 3.40.50.1440 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Tubulin/FtsZ, GTPase domain | 0.59 | 54.0 | 4.38e-01 | 100.0% | 53.2% |
| 4om8A01 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.59 | 54.0 | 5.00e-01 | 98.7% | 90.8% |
| 3lv8A00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.59 | 53.0 | 4.80e-01 | 100.0% | 99.0% |
| 6d2xA01 | 3.20.20.80 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases | 0.58 | 45.0 | 3.60e-01 | 84.0% | 93.5% |
| 4xxhA01 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.58 | 45.0 | 4.69e-01 | 100.0% | 89.1% |
| 3l4eA00 | 3.40.50.880 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Class I glutamine amidotransferase (GATase) domain | 0.57 | 52.0 | 4.71e-01 | 99.3% | 83.2% |
| 4zdjA02 | 3.40.50.880 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Class I glutamine amidotransferase (GATase) domain | 0.57 | 52.0 | 4.43e-01 | 100.0% | 95.0% |
| 3cqjA00 | 3.20.20.150 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Divalent-metal-dependent TIM barrel enzymes | 0.57 | 45.0 | 3.68e-01 | 83.3% | 86.6% |
| 3hs3A02 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.56 | 43.0 | 4.50e-01 | 100.0% | 87.7% |
| 2w7tA00 | 3.40.50.880 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Class I glutamine amidotransferase (GATase) domain | 0.56 | 51.0 | 4.26e-01 | 100.0% | 92.8% |
| 2ah5A01 | 3.40.50.1000 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like | 0.56 | 49.0 | 5.03e-01 | 96.7% | 97.9% |
| 5oycB00 | 3.20.20.80 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases | 0.56 | 43.0 | 3.27e-01 | 81.3% | 80.9% |
| 4hjwA00 | 3.20.20.140 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Metal-dependent hydrolases | 0.54 | 47.0 | 3.56e-01 | 94.7% | 90.9% |
| 3ckmA01 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.54 | 48.0 | 4.61e-01 | 100.0% | 82.5% |
| 3rq1A02 | 3.40.640.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) | 0.54 | 48.0 | 4.18e-01 | 100.0% | 69.5% |
| 2r6oA00 | 3.20.20.450 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › EAL domain | 0.54 | 42.0 | 3.52e-01 | 82.0% | 92.2% |
| 5xmvA02 | 3.40.640.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) | 0.54 | 49.0 | 4.03e-01 | 99.3% | 56.3% |
| 6o1wA01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.54 | 45.0 | 3.83e-01 | 92.0% | 79.2% |
| 5xgbA03 | 3.20.20.450 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › EAL domain | 0.54 | 41.0 | 3.53e-01 | 81.3% | 90.8% |
| 4k36B00 | 3.20.20.70 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I | 0.53 | 48.0 | 3.63e-01 | 98.7% | 98.6% |
| 3eleA02 | 3.40.640.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) | 0.53 | 48.0 | 4.14e-01 | 98.7% | 68.5% |
| 4ocaA01 | 3.40.640.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) | 0.53 | 47.0 | 4.01e-01 | 98.7% | 60.8% |
| 2zjgA02 | 3.40.640.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) | 0.52 | 47.0 | 3.96e-01 | 99.3% | 61.3% |
| 3dliA00 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.52 | 48.0 | 4.19e-01 | 100.0% | 86.0% |
| 4gxwB00 | 3.20.20.140 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Metal-dependent hydrolases | 0.50 | 44.0 | 3.39e-01 | 97.3% | 86.0% |
| 3oqvA00 | 3.40.50.11710 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Cyclodipeptide synthase | 0.50 | 43.0 | 3.88e-01 | 93.3% | 99.1% |
| 3qtgA01 | 3.20.20.60 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Phosphoenolpyruvate-binding domains | 0.50 | 45.0 | 3.88e-01 | 98.7% | 87.9% |
| 4hu4A00 | 3.20.20.450 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › EAL domain | 0.50 | 39.0 | 3.43e-01 | 84.7% | 82.6% |
ECOD (85)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3487525 | 2007.9.1.4 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Toll/Interleukin receptor TIR domain › Toll/Interleukin receptor TIR domain › TIR_2 | 0.89 | 75.0 | 7.35e-01 | 100.0% | 81.2% |
| 4966509 | 2007.9.1.4 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Toll/Interleukin receptor TIR domain › Toll/Interleukin receptor TIR domain › TIR_2 | 0.86 | 71.0 | 7.44e-01 | 100.0% | 94.1% |
| 4974232 | 2007.9.1.4 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Toll/Interleukin receptor TIR domain › Toll/Interleukin receptor TIR domain › TIR_2 | 0.85 | 72.0 | 7.28e-01 | 100.0% | 88.0% |
| 3590648 | 2007.9.1.4 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Toll/Interleukin receptor TIR domain › Toll/Interleukin receptor TIR domain › TIR_2 | 0.84 | 76.0 | 7.77e-01 | 99.3% | 97.9% |
| 3289646 | 2007.9.1.4 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Toll/Interleukin receptor TIR domain › Toll/Interleukin receptor TIR domain › TIR_2 | 0.83 | 68.0 | 7.05e-01 | 100.0% | 90.7% |
| 2663794 | 2007.9.1.4 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Toll/Interleukin receptor TIR domain › Toll/Interleukin receptor TIR domain › TIR_2 | 0.82 | 66.0 | 6.95e-01 | 99.3% | 90.6% |
| 3924007 | 2007.9.1.0 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Toll/Interleukin receptor TIR domain › Toll/Interleukin receptor TIR domain | 0.82 | 71.0 | 6.94e-01 | 100.0% | 83.7% |
| 5029149 | 2007.15.1.17 ↗ | a/b three-layered sandwiches › Flavodoxin-like › N-deoxyribosyltransferase › N-deoxyribosyltransferase › ThsB_TIR | 0.81 | 64.0 | 7.03e-01 | 98.7% | 98.4% |
| 2171504 | 2007.9.1.2 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Toll/Interleukin receptor TIR domain › Toll/Interleukin receptor TIR domain › SEFIR | 0.81 | 74.0 | 7.34e-01 | 100.0% | 93.5% |
| 3886723 | 2007.9.1.1 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Toll/Interleukin receptor TIR domain › Toll/Interleukin receptor TIR domain › TIR | 0.80 | 75.0 | 7.47e-01 | 100.0% | 94.8% |
| 3400102 | 2007.9.1.4 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Toll/Interleukin receptor TIR domain › Toll/Interleukin receptor TIR domain › TIR_2 | 0.80 | 70.0 | 6.88e-01 | 100.0% | 85.6% |
| 4105521 | 2007.9.1.1 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Toll/Interleukin receptor TIR domain › Toll/Interleukin receptor TIR domain › TIR | 0.80 | 72.0 | 7.20e-01 | 100.0% | 92.2% |
| 3904535 | 2007.9.1.1 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Toll/Interleukin receptor TIR domain › Toll/Interleukin receptor TIR domain › TIR | 0.79 | 72.0 | 6.98e-01 | 100.0% | 86.7% |
| 3748796 | 2007.9.1.1 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Toll/Interleukin receptor TIR domain › Toll/Interleukin receptor TIR domain › TIR | 0.79 | 73.0 | 7.20e-01 | 99.3% | 92.9% |
| 3932663 | 2007.9.1.0 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Toll/Interleukin receptor TIR domain › Toll/Interleukin receptor TIR domain | 0.79 | 74.0 | 7.32e-01 | 98.7% | 98.1% |
| 3212490 | 2007.9.1.2 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Toll/Interleukin receptor TIR domain › Toll/Interleukin receptor TIR domain › SEFIR | 0.78 | 74.0 | 6.61e-01 | 100.0% | 77.5% |
| 3502906 | 2007.9.1.2 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Toll/Interleukin receptor TIR domain › Toll/Interleukin receptor TIR domain › SEFIR | 0.77 | 70.0 | 7.16e-01 | 98.0% | 97.9% |
| 3863608 | 2007.9.1.1 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Toll/Interleukin receptor TIR domain › Toll/Interleukin receptor TIR domain › TIR | 0.77 | 73.0 | 6.80e-01 | 99.3% | 85.6% |
| 4500387 | 2007.9.1.4 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Toll/Interleukin receptor TIR domain › Toll/Interleukin receptor TIR domain › TIR_2 | 0.77 | 65.0 | 6.67e-01 | 100.0% | 91.7% |
| 3914259 | 2007.9.1.0 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Toll/Interleukin receptor TIR domain › Toll/Interleukin receptor TIR domain | 0.77 | 70.0 | 4.32e-01 | 99.3% | 18.9% |
| 3545820 | 2007.9.1.0 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Toll/Interleukin receptor TIR domain › Toll/Interleukin receptor TIR domain | 0.76 | 68.0 | 4.68e-01 | 99.3% | 30.5% |
| 3354777 | 2007.9.1.0 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Toll/Interleukin receptor TIR domain › Toll/Interleukin receptor TIR domain | 0.75 | 69.0 | 6.73e-01 | 100.0% | 89.1% |
| 3514166 | 2007.9.1.2 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Toll/Interleukin receptor TIR domain › Toll/Interleukin receptor TIR domain › SEFIR | 0.74 | 71.0 | 6.46e-01 | 100.0% | 81.1% |
| 3815345 | 2007.9.1.1 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Toll/Interleukin receptor TIR domain › Toll/Interleukin receptor TIR domain › TIR | 0.74 | 70.0 | 6.56e-01 | 100.0% | 92.8% |
| 3836444 | 2007.9.1.1 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Toll/Interleukin receptor TIR domain › Toll/Interleukin receptor TIR domain › TIR | 0.74 | 70.0 | 6.67e-01 | 100.0% | 96.5% |
| 4681655 | 4978.1.1.2 ↗ | a/b three-layered sandwiches › a/b domain in AF0625-like proteins › a/b domain in AF0625-like proteins › a/b domain in AF0625-like proteins › DUF2325 | 0.74 | 46.0 | 5.74e-01 | 100.0% | 100.0% |
| 3819546 | 2007.9.1.1 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Toll/Interleukin receptor TIR domain › Toll/Interleukin receptor TIR domain › TIR | 0.74 | 69.0 | 6.41e-01 | 100.0% | 88.6% |
| 3423652 | 2007.9.1.4 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Toll/Interleukin receptor TIR domain › Toll/Interleukin receptor TIR domain › TIR_2 | 0.73 | 69.0 | 6.39e-01 | 100.0% | 91.4% |
| 3334103 | 2007.9.1.4 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Toll/Interleukin receptor TIR domain › Toll/Interleukin receptor TIR domain › TIR_2 | 0.73 | 69.0 | 6.37e-01 | 100.0% | 89.2% |
| 3812588 | 2007.9.1.1 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Toll/Interleukin receptor TIR domain › Toll/Interleukin receptor TIR domain › TIR | 0.73 | 69.0 | 6.35e-01 | 100.0% | 87.0% |
| 4264224 | 2007.15.1.2 ↗ | a/b three-layered sandwiches › Flavodoxin-like › N-deoxyribosyltransferase › N-deoxyribosyltransferase › Nuc_deoxyrib_tr | 0.71 | 67.0 | 6.62e-01 | 100.0% | 97.5% |
| 3831926 | 2007.9.1.1 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Toll/Interleukin receptor TIR domain › Toll/Interleukin receptor TIR domain › TIR | 0.71 | 67.0 | 5.95e-01 | 100.0% | 87.8% |
| 4091927 | 2004.1.1.414 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › GTP_EFTU, MMR_HSR1 | 0.71 | 65.0 | 5.86e-01 | 100.0% | 87.8% |
| 2772046 | 2007.9.1.1 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Toll/Interleukin receptor TIR domain › Toll/Interleukin receptor TIR domain › TIR | 0.71 | 63.0 | 6.17e-01 | 100.0% | 87.7% |
| 3652604 | 2007.9.1.0 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Toll/Interleukin receptor TIR domain › Toll/Interleukin receptor TIR domain | 0.70 | 66.0 | 6.07e-01 | 100.0% | 84.7% |
| 3911725 | 2007.9.1.1 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Toll/Interleukin receptor TIR domain › Toll/Interleukin receptor TIR domain › TIR | 0.70 | 64.0 | 6.13e-01 | 99.3% | 85.3% |
| 4970634 | 2004.1.1.73 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MMR_HSR1 | 0.69 | 63.0 | 5.57e-01 | 100.0% | 83.6% |
| 4056920 | 2004.1.1.73 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MMR_HSR1 | 0.69 | 63.0 | 5.69e-01 | 100.0% | 90.7% |
| 5079282 | 2004.1.1.73 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MMR_HSR1 | 0.69 | 63.0 | 5.72e-01 | 100.0% | 92.0% |
| 3588626 | 2007.1.2.8 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › ABC_sub_bind | 0.69 | 45.0 | 4.85e-01 | 87.3% | 76.9% |
| 5032866 | 2007.1.3.4 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › B12-binding | 0.68 | 60.0 | 5.50e-01 | 100.0% | 72.3% |
| 3250671 | 2007.19.1.1 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Glycerate kinase I (Pfam 02595) domain I › Glycerate kinase I (Pfam 02595) domain I › Gly_kinase | 0.68 | 63.0 | 6.05e-01 | 100.0% | 98.8% |
| 2142018 | 2007.12.1.0 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Beta-D-glucan exohydrolase, C-terminal domain › Beta-D-glucan exohydrolase, C-terminal domain | 0.67 | 56.0 | 5.41e-01 | 97.3% | 77.8% |
| 3461639 | 7512.1.1.66 ↗ | a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Exostosin_GT47 | 0.67 | 57.0 | 4.68e-01 | 100.0% | 52.3% |
| 3423422 | 7512.1.1.66 ↗ | a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Exostosin_GT47 | 0.66 | 55.0 | 4.56e-01 | 100.0% | 50.2% |
| 5046572 | 2004.1.1.19 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Ras | 0.66 | 61.0 | 5.78e-01 | 100.0% | 95.0% |
| 1173105 | 2007.1.2.2 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › Peripla_BP_1 | 0.64 | 41.0 | 4.99e-01 | 88.7% | 100.0% |
| 3595109 | 2003.1.1.0 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains | 0.64 | 58.0 | 4.22e-01 | 100.0% | 56.9% |
| 4647619 | 2004.1.1.19 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Ras | 0.64 | 59.0 | 5.39e-01 | 100.0% | 85.1% |
| 1406860 | 2007.1.2.10 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › Peripla_BP_3 | 0.63 | 40.0 | 4.77e-01 | 88.7% | 96.9% |
| 3869053 | 2003.1.1.160 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › 3Beta_HSD, NmrA | 0.62 | 57.0 | 4.27e-01 | 100.0% | 64.3% |
| 4974906 | 2003.1.1.20 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › Epimerase | 0.62 | 57.0 | 4.51e-01 | 100.0% | 70.5% |
| 3987390 | 2007.1.2.11 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › Peripla_BP_4 | 0.62 | 48.0 | 4.96e-01 | 100.0% | 86.4% |
| 3807997 | 2007.2.1.8 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › Flavoproteins › Glyco_transf_61 | 0.62 | 57.0 | 4.91e-01 | 100.0% | 67.2% |
| 3815881 | 2007.1.1.22 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Class I glutamine amidotransferase-like › Glyco_transf_61 | 0.62 | 57.0 | 5.04e-01 | 100.0% | 73.0% |
| 2050960 | 2007.1.2.2 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › Peripla_BP_1 | 0.62 | 41.0 | 4.77e-01 | 88.7% | 97.1% |
| 4022058 | 2003.1.1.61 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › KR | 0.61 | 56.0 | 4.52e-01 | 100.0% | 77.2% |
| 4999884 | 7512.1.1.30 ↗ | a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_4 | 0.61 | 57.0 | 4.96e-01 | 100.0% | 94.5% |
| 3706843 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.61 | 56.0 | 5.25e-01 | 100.0% | 92.4% |
| 4975753 | 7545.1.1.1 ↗ | a/b three-layered sandwiches › YchN-like › YchN-like › YchN-like › DsrE | 0.61 | 43.0 | 4.73e-01 | 100.0% | 91.6% |
| 4274853 | 2003.1.1.61 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › KR | 0.61 | 56.0 | 4.48e-01 | 100.0% | 75.2% |
| 4121748 | 2003.1.1.61 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › KR | 0.61 | 55.0 | 4.42e-01 | 100.0% | 73.0% |
| 223415 | 2007.5.1.8 ↗ | a/b three-layered sandwiches › Flavodoxin-like › SGNH hydrolase › SGNH hydrolase › Lipase_GDSL_2 | 0.61 | 56.0 | 4.95e-01 | 100.0% | 87.7% |
| 3589002 | 2007.1.2.8 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › ABC_sub_bind | 0.60 | 46.0 | 4.58e-01 | 100.0% | 76.2% |
| 5044852 | 2007.1.1.24 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Class I glutamine amidotransferase-like › DUF4350 | 0.60 | 55.0 | 4.66e-01 | 100.0% | 97.1% |
| 4046481 | 2007.1.3.28 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Glyco_transf_61 | 0.59 | 53.0 | 4.43e-01 | 100.0% | 56.5% |
| 2066778 | 2007.1.2.0 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I | 0.59 | 38.0 | 4.49e-01 | 89.3% | 98.0% |
| 3222006 | 7502.1.1.0 ↗ | a/b three-layered sandwiches › Anticodon-binding domain of Class II aaRS › Anticodon-binding domain of Class II aaRS › Anticodon-binding domain of Class II aaRS | 0.59 | 38.0 | 4.43e-01 | 100.0% | 96.0% |
| 3775044 | 7512.1.1.88 ↗ | a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_61 | 0.59 | 54.0 | 4.59e-01 | 100.0% | 63.0% |
| 4974557 | 7512.1.1.0 ↗ | a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase | 0.58 | 51.0 | 5.28e-01 | 94.0% | 100.0% |
| 1253076 | 2007.1.2.10 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › Peripla_BP_3 | 0.58 | 41.0 | 4.36e-01 | 88.7% | 84.5% |
| 4929229 | 2002.1.1.232 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Fer4_12 | 0.55 | 48.0 | 4.15e-01 | 93.3% | 90.4% |
| 3716242 | 2005.1.1.0 ↗ | a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains | 0.55 | 46.0 | 3.96e-01 | 90.7% | 82.9% |
| 5055301 | 2002.1.1.120 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Radical_SAM | 0.55 | 47.0 | 4.10e-01 | 94.0% | 91.5% |
| 5044211 | 2002.1.1.120 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Radical_SAM | 0.55 | 47.0 | 3.40e-01 | 92.0% | 58.6% |
| 5035607 | 2002.1.1.60 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › AP_endonuc_2 | 0.55 | 43.0 | 3.71e-01 | 83.3% | 87.7% |
| 4031586 | 2007.1.14.6 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Chelatase-like › CbiX | 0.55 | 38.0 | 3.96e-01 | 91.3% | 77.8% |
| 3804609 | 2005.1.1.13 ↗ | a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › CTP_transf_like | 0.54 | 45.0 | 4.12e-01 | 90.7% | 78.5% |
| 3855879 | 2006.1.4.0 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like | 0.54 | 41.0 | 3.99e-01 | 80.0% | 88.8% |
| 4146733 | 2007.1.5.2 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › ATC-like › CCG | 0.54 | 41.0 | 4.41e-01 | 97.3% | 96.8% |
| 3596792 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.54 | 48.0 | 4.73e-01 | 99.3% | 100.0% |
| 4948637 | 2002.1.1.120 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Radical_SAM | 0.53 | 47.0 | 3.80e-01 | 95.3% | 93.7% |
| 3763738 | 2005.1.1.0 ↗ | a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains | 0.53 | 40.0 | 3.91e-01 | 79.3% | 90.0% |
| 5068261 | 2004.1.1.200 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_25 | 0.53 | 46.0 | 3.97e-01 | 96.0% | 76.3% |
| 5036242 | 2002.1.1.120 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Radical_SAM | 0.52 | 46.0 | 3.50e-01 | 95.3% | 58.6% |