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Transcription_elongation_factor_S-II
Euk-VirMollivirus_sibericum_Viruses.
Transcription_elongation_factor_S-II__YP_009165397__Mollivirus_sibericum_Viruses.__X
Identity
- Accession:
- YP_009165397 ↗
- Protein ID:
- Transcription_elongation_factor_S-II
- Kingdom:
- euk
Quality
58.3
mean pLDDT
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 109-211
Domain cluster:
representative
CATH (27)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2a7oA00 | 1.10.1740.100 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › Set2, Rpb1 interacting domain | 0.75 | 59.0 | 6.06e-01 | 91.3% | 86.0% |
| 4cxfA01 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.69 | 45.0 | 4.88e-01 | 90.3% | 79.3% |
| 2i5uA00 | 1.10.10.630 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › DnaD domain-like | 0.68 | 45.0 | 5.09e-01 | 90.3% | 90.9% |
| 2vk9A03 | 1.10.3730.30 | Mainly Alpha › Orthogonal Bundle › ProC C-terminal domain-like fold › | 0.63 | 46.0 | 4.69e-01 | 78.6% | 79.6% |
| 3if8B02 | 1.20.58.730 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.62 | 43.0 | 4.42e-01 | 97.1% | 74.0% |
| 2odmA00 | 1.10.287.750 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › SO2669-like | 0.61 | 35.0 | 4.02e-01 | 71.8% | 74.7% |
| 4i8qA01 | 3.40.605.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 | 0.61 | 42.0 | 3.05e-01 | 71.8% | 53.3% |
| 3llkA02 | 1.20.120.310 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › ERV/ALR sulfhydryl oxidase domain | 0.61 | 37.0 | 3.30e-01 | 86.4% | 42.7% |
| 2p5tA00 | 1.10.8.130 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.60 | 43.0 | 4.57e-01 | 83.5% | 83.7% |
| 4m70B00 | 1.10.246.200 | Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › WPP domain | 0.60 | 47.0 | 4.96e-01 | 90.3% | 94.5% |
| 7w5lA01 | 3.40.605.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 | 0.59 | 41.0 | 3.09e-01 | 70.9% | 61.4% |
| 3bg2A03 | 1.10.3410.10 | Mainly Alpha › Orthogonal Bundle › putative deoxyguanosinetriphosphate triphosphohydrolase fold › putative deoxyguanosinetriphosphate triphosphohydrolase like domain | 0.59 | 46.0 | 4.72e-01 | 83.5% | 94.8% |
| 4bemJ00 | 1.20.120.610 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase | 0.58 | 51.0 | 4.32e-01 | 100.0% | 90.1% |
| 4an8A02 | 1.10.132.100 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › | 0.58 | 46.0 | 4.41e-01 | 86.4% | 73.0% |
| 6cgvM01 | 1.20.120.1500 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Pre-hexon-linking protein IIIa | 0.57 | 35.0 | 3.28e-01 | 80.6% | 45.5% |
| 4od4A01 | 1.10.357.140 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › UbiA prenyltransferase | 0.57 | 46.0 | 4.01e-01 | 86.4% | 60.9% |
| 4od4A02 | 1.20.120.1780 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › UbiA prenyltransferase | 0.57 | 39.0 | 3.80e-01 | 71.8% | 77.3% |
| 2pkeA02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.57 | 34.0 | 3.72e-01 | 81.6% | 75.6% |
| 2au5A00 | 1.20.120.590 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › EF2947-like | 0.57 | 45.0 | 4.23e-01 | 86.4% | 73.6% |
| 3o3mB01 | 1.20.1270.370 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.56 | 38.0 | 3.83e-01 | 74.8% | 68.9% |
| 3s84A02 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.56 | 44.0 | 3.90e-01 | 87.4% | 83.4% |
| 8etcb01 | 1.20.120.1190 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.53 | 42.0 | 3.77e-01 | 86.4% | 72.6% |
| 3mvuA00 | 1.20.910.10 | Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like | 0.52 | 46.0 | 3.63e-01 | 100.0% | 79.0% |
| 1on2A02 | 1.10.60.10 | Mainly Alpha › Orthogonal Bundle › Diphtheria Toxin Repressor; domain 2 › Iron dependent repressor, metal binding and dimerisation domain | 0.52 | 31.0 | 3.75e-01 | 90.3% | 96.8% |
| 1w36F02 | 1.10.10.160 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › | 0.51 | 41.0 | 4.23e-01 | 92.2% | 88.0% |
| 3piwA00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.51 | 44.0 | 3.86e-01 | 94.2% | 67.5% |
| 6m9sB01 | 1.20.910.10 | Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like | 0.50 | 44.0 | 3.53e-01 | 100.0% | 76.0% |
ECOD (37)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3748217 | 103.4.1.2 ↗ | alpha arrays › RuvA-C › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › TFIIS_M | 0.84 | 71.0 | 6.68e-01 | 100.0% | 75.0% |
| 3841170 | 103.4.1.2 ↗ | alpha arrays › RuvA-C › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › TFIIS_M | 0.79 | 66.0 | 6.40e-01 | 96.1% | 79.1% |
| 3861204 | 103.4.1.2 ↗ | alpha arrays › RuvA-C › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › TFIIS_M | 0.79 | 71.0 | 6.94e-01 | 100.0% | 89.1% |
| 3676120 | 103.4.1.2 ↗ | alpha arrays › RuvA-C › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › TFIIS_M | 0.77 | 71.0 | 6.95e-01 | 100.0% | 90.9% |
| 3191012 | 103.4.1.2 ↗ | alpha arrays › RuvA-C › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › TFIIS_M | 0.76 | 70.0 | 6.99e-01 | 98.1% | 96.2% |
| 3706616 | 2003.1.5.46 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › MTS | 0.66 | 55.0 | 3.76e-01 | 97.1% | 27.5% |
| 3168800 | 148.1.3.40 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › ORC5_lid | 0.62 | 55.0 | 5.32e-01 | 99.0% | 93.0% |
| 3216944 | 5050.1.1.11 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › UNC-93 | 0.61 | 49.0 | 3.79e-01 | 85.4% | 85.0% |
| 4939889 | 547.1.1.1 ↗ | alpha duplicates or obligate multimers › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › GlutR_dimer | 0.61 | 46.0 | 4.39e-01 | 79.6% | 72.5% |
| 3370969 | 161.1.1.7 ↗ | alpha complex topology › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA › Serinc | 0.60 | 50.0 | 4.47e-01 | 91.3% | 71.7% |
| 3542784 | 5079.1.1.1 ↗ | alpha duplicates or obligate multimers › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › MgtE | 0.60 | 46.0 | 3.62e-01 | 83.5% | 76.9% |
| 3388735 | 5050.1.1.11 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › UNC-93 | 0.59 | 46.0 | 3.59e-01 | 84.5% | 80.9% |
| 4026826 | 3651.1.1.0 ↗ | alpha bundles › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › Translation initiation factor eIF-2B delta subunit N-terminal helical domain | 0.59 | 45.0 | 4.21e-01 | 89.3% | 64.6% |
| 3715674 | 142.1.1.0 ↗ | alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors | 0.58 | 46.0 | 4.88e-01 | 89.3% | 98.9% |
| 3218491 | 5054.1.1.70 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Yip1 | 0.58 | 51.0 | 4.33e-01 | 97.1% | 92.4% |
| 3594000 | 5054.1.1.0 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels | 0.58 | 51.0 | 4.21e-01 | 98.1% | 93.7% |
| 4986966 | 601.30.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Helical bundle domain in hypothetical protein PH1320 › Helical bundle domain in hypothetical protein PH1320 › NOG1_N | 0.57 | 46.0 | 3.99e-01 | 86.4% | 68.4% |
| 5037454 | 7014.1.1.0 ↗ | alpha bundles › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain | 0.57 | 38.0 | 3.96e-01 | 87.4% | 73.7% |
| 3605990 | 5054.1.1.70 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Yip1 | 0.57 | 50.0 | 4.13e-01 | 99.0% | 92.1% |
| 3750261 | 192.8.1.421 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › DUF4745 | 0.57 | 46.0 | 4.19e-01 | 86.4% | 87.4% |
| 5025147 | 601.30.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Helical bundle domain in hypothetical protein PH1320 › Helical bundle domain in hypothetical protein PH1320 › NOG1_N | 0.56 | 45.0 | 3.96e-01 | 86.4% | 68.4% |
| 3390728 | 601.19.1.47 ↗ | alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein › DUF4745 | 0.56 | 45.0 | 4.26e-01 | 86.4% | 88.0% |
| 3867410 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.55 | 45.0 | 3.89e-01 | 87.4% | 85.0% |
| 4999413 | 1075.5.1.8 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt_3 | 0.55 | 49.0 | 3.63e-01 | 100.0% | 66.8% |
| 5035899 | 601.30.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Helical bundle domain in hypothetical protein PH1320 › Helical bundle domain in hypothetical protein PH1320 › NOG1_N | 0.55 | 43.0 | 3.79e-01 | 86.4% | 66.3% |
| 4974404 | 7014.1.1.1 ↗ | alpha bundles › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › BacA | 0.54 | 36.0 | 3.45e-01 | 87.4% | 59.2% |
| 3658108 | 611.7.1.15 ↗ | alpha bundles › N-cbl like › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Rx_N | 0.53 | 45.0 | 4.11e-01 | 97.1% | 90.3% |
| 4013477 | 1025.1.1.0 ↗ | alpha bundles › Stonustoxin helical domain › Stonustoxin helical domain › Stonustoxin helical domain | 0.53 | 41.0 | 4.04e-01 | 83.5% | 87.3% |
| 4255110 | 2485.1.1.42 ↗ | a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like › Thioredoxin_5 | 0.52 | 47.0 | 3.75e-01 | 99.0% | 56.6% |
| 3799895 | 601.4.1.59 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › Piezo_THU9_anchor | 0.52 | 40.0 | 3.62e-01 | 83.5% | 60.0% |
| 4956617 | 601.30.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Helical bundle domain in hypothetical protein PH1320 › Helical bundle domain in hypothetical protein PH1320 › NOG1_N | 0.52 | 41.0 | 3.59e-01 | 86.4% | 66.3% |
| 4974861 | 1075.5.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter | 0.52 | 45.0 | 3.41e-01 | 99.0% | 67.9% |
| 3589253 | 5067.1.1.6 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › YibE_F | 0.51 | 45.0 | 3.46e-01 | 100.0% | 62.0% |
| 3210386 | 109.3.1.154 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › DUF7719 | 0.51 | 43.0 | 4.09e-01 | 100.0% | 79.2% |
| 2663405 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.51 | 41.0 | 3.24e-01 | 88.3% | 75.2% |
| 3386126 | 191.1.1.0 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain | 0.50 | 39.0 | 3.57e-01 | 80.6% | 83.8% |
| 3746563 | 3755.3.1.123 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › Tektin | 0.50 | 40.0 | 3.57e-01 | 86.4% | 87.3% |
D2
medium
residues 248-297
Domain cluster:
rep: putative_transcription_elongation_factor_S-II-related_protein__YP_009507517__Heterosigma_akashiwo_virus_01__97195__D153-194
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01096.24 best | Zn_ribbon_TFIIS | 38.8 | 9.20e-10 | 82.0% | 97.4% |