←Back to structures
Translation_initiation_factor_4E
Euk-VirAcanthamoeba_polyphaga_moumouvirus
Translation_initiation_factor_4E__YP_007354285__Acanthamoeba_polyphaga_moumouvirus__1269028
Identity
- Accession:
- YP_007354285 ↗
- Protein ID:
- Translation_initiation_factor_4E
- Kingdom:
- euk
Quality
71.5
mean pLDDT
Taxonomy
Bamfordvirae›
Nucleocytoviricota›
Megaviricetes›
Imitervirales›
Mimiviridae›
Moumouvirus›
Acanthamoeba_polyphaga_moumouvirus
TaxID: 1269028
Cluster
View cluster (13 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 19-75
Domain cluster:
representative
CATH (13)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5abxA00 | 3.30.760.10 | Alpha Beta › 2-Layer Sandwich › RNA Cap, Translation Initiation Factor Eif4e › RNA Cap, Translation Initiation Factor Eif4e | 0.77 | 62.0 | 4.35e-01 | 98.2% | 28.9% |
| 2wmcA00 | 3.30.760.10 | Alpha Beta › 2-Layer Sandwich › RNA Cap, Translation Initiation Factor Eif4e › RNA Cap, Translation Initiation Factor Eif4e | 0.74 | 61.0 | 4.32e-01 | 96.5% | 29.9% |
| 2jgbA01 | 3.30.760.10 | Alpha Beta › 2-Layer Sandwich › RNA Cap, Translation Initiation Factor Eif4e › RNA Cap, Translation Initiation Factor Eif4e | 0.71 | 58.0 | 4.07e-01 | 96.5% | 29.5% |
| 2v5gA00 | 3.40.1690.10 | Alpha Beta › 3-Layer(aba) Sandwich › name from scop › secretion proteins EscU | 0.67 | 46.0 | 3.61e-01 | 87.7% | 34.2% |
| 3t7yA00 | 3.40.1690.10 | Alpha Beta › 3-Layer(aba) Sandwich › name from scop › secretion proteins EscU | 0.67 | 43.0 | 3.71e-01 | 91.2% | 40.4% |
| 3bzvB00 | 3.40.1690.10 | Alpha Beta › 3-Layer(aba) Sandwich › name from scop › secretion proteins EscU | 0.66 | 43.0 | 3.93e-01 | 91.2% | 48.8% |
| 6cngA03 | 3.30.1180.10 | Alpha Beta › 2-Layer Sandwich › Hypothetical Protein Tm841; Chain: A;domain 3 › | 0.59 | 39.0 | 3.12e-01 | 87.7% | 30.5% |
| 2g7jA00 | 3.90.1150.40 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Protein of unknown function DUF2002 | 0.57 | 43.0 | 3.62e-01 | 89.5% | 100.0% |
| 4efjA01 | 3.10.28.10 | Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases | 0.54 | 41.0 | 3.25e-01 | 89.5% | 77.9% |
| 4bpxD00 | 1.20.930.80 | Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › | 0.54 | 35.0 | 2.46e-01 | 98.2% | 18.3% |
| 5tf0B03 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.53 | 36.0 | 3.03e-01 | 86.0% | 37.8% |
| 2wnsA00 | 3.40.50.2020 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.50 | 38.0 | 2.74e-01 | 87.7% | 98.0% |
| 1o22A00 | 3.90.1000.10 | Alpha Beta › Alpha-Beta Complex › Orphan Protein Tm0875; Chain: A; › Hypothetical protein TM0875 | 0.50 | 35.0 | 2.73e-01 | 77.2% | 94.0% |
ECOD (19)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3355743 | 317.1.1.1 ↗ | a+b two layers › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › IF4E | 0.79 | 68.0 | 4.76e-01 | 98.2% | 32.1% |
| 3457076 | 317.1.1.1 ↗ | a+b two layers › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › IF4E | 0.75 | 64.0 | 4.40e-01 | 100.0% | 27.8% |
| 3594318 | 317.1.1.1 ↗ | a+b two layers › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › IF4E | 0.74 | 63.0 | 4.26e-01 | 94.7% | 27.8% |
| 3270677 | 317.1.1.1 ↗ | a+b two layers › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › IF4E | 0.72 | 64.0 | 4.39e-01 | 100.0% | 30.5% |
| 4190134 | 4104.1.1.1 ↗ | beta sandwiches › EscU C-terminal domain-like › EscU C-terminal domain-like › EscU C-terminal domain-like › Bac_export_2 | 0.67 | 46.0 | 4.04e-01 | 86.0% | 48.2% |
| 351874 | 4104.1.1.1 ↗ | beta sandwiches › EscU C-terminal domain-like › EscU C-terminal domain-like › EscU C-terminal domain-like › Bac_export_2 | 0.67 | 45.0 | 3.58e-01 | 86.0% | 33.6% |
| 340177 | 4104.1.1.1 ↗ | beta sandwiches › EscU C-terminal domain-like › EscU C-terminal domain-like › EscU C-terminal domain-like › Bac_export_2 | 0.64 | 41.0 | 3.57e-01 | 91.2% | 40.4% |
| 3409489 | 59.1.1.6 ↗ | beta complex topology › triple barrel › triple barrel › Rap30/74 interaction domains-like › TFIIIC_sub6 | 0.61 | 44.0 | 3.73e-01 | 82.5% | 46.3% |
| 3991612 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.60 | 43.0 | 2.92e-01 | 77.2% | 98.2% |
| 3929615 | 59.1.1.8 ↗ | beta complex topology › triple barrel › triple barrel › Rap30/74 interaction domains-like › TFIIF_beta_N | 0.60 | 42.0 | 3.28e-01 | 82.5% | 33.6% |
| 3970435 | 101.1.2.379 ↗ | alpha arrays › HTH › HTH › winged helix domain › NGO1945_C | 0.59 | 38.0 | 3.07e-01 | 91.2% | 31.1% |
| 3565424 | 220.1.1.22 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › FERM_C | 0.57 | 44.0 | 3.54e-01 | 87.7% | 40.8% |
| 4443852 | 10.12.1.1 ↗ | beta sandwiches › jelly-roll › Double-stranded beta-helix › Double-stranded beta-helix › cNMP_binding | 0.57 | 48.0 | 3.47e-01 | 100.0% | 54.9% |
| 3397090 | 12.1.1.0 ↗ | beta sandwiches › Glycosyl hydrolase domain-like › Glycosyl hydrolase domain › Glycosyl hydrolase domain | 0.54 | 40.0 | 3.10e-01 | 82.5% | 72.7% |
| 3191084 | 59.1.1.6 ↗ | beta complex topology › triple barrel › triple barrel › Rap30/74 interaction domains-like › TFIIIC_sub6 | 0.54 | 40.0 | 3.67e-01 | 82.5% | 60.0% |
| 4055235 | 2484.1.1.41 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › AnmK | 0.52 | 40.0 | 2.83e-01 | 91.2% | 93.2% |
| 3233752 | 1016.1.1.0 ↗ | alpha arrays › Dimerization domain in caprin-1 and PAN3 › Dimerization domain in caprin-1 and PAN3 › Dimerization domain in caprin-1 and PAN3 | 0.51 | 43.0 | 3.37e-01 | 100.0% | 45.2% |
| 3499566 | 5.1.4.1 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40 | 0.51 | 39.0 | 2.37e-01 | 91.2% | 85.6% |
| 3210551 | 304.7.1.0 ↗ | a+b two layers › Alpha-beta plaits › Protease propeptides/inhibitors › Protease propeptides/inhibitors | 0.51 | 40.0 | 3.56e-01 | 93.0% | 88.9% |
D2
medium
residues 92-224
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01652.25 best | IF4E | 59.3 | 5.30e-16 | 99.2% | 62.5% |
CATH (67)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2jgbA01 | 3.30.760.10 | Alpha Beta › 2-Layer Sandwich › RNA Cap, Translation Initiation Factor Eif4e › RNA Cap, Translation Initiation Factor Eif4e | 0.84 | 70.0 | 6.34e-01 | 99.2% | 67.1% |
| 2wmcA00 | 3.30.760.10 | Alpha Beta › 2-Layer Sandwich › RNA Cap, Translation Initiation Factor Eif4e › RNA Cap, Translation Initiation Factor Eif4e | 0.83 | 69.0 | 6.25e-01 | 99.2% | 66.1% |
| 3hxiA01 | 3.30.760.10 | Alpha Beta › 2-Layer Sandwich › RNA Cap, Translation Initiation Factor Eif4e › RNA Cap, Translation Initiation Factor Eif4e | 0.83 | 69.0 | 6.27e-01 | 97.0% | 67.3% |
| 5abxA00 | 3.30.760.10 | Alpha Beta › 2-Layer Sandwich › RNA Cap, Translation Initiation Factor Eif4e › RNA Cap, Translation Initiation Factor Eif4e | 0.82 | 70.0 | 6.27e-01 | 99.2% | 67.6% |
| 4b6uA00 | 3.30.760.10 | Alpha Beta › 2-Layer Sandwich › RNA Cap, Translation Initiation Factor Eif4e › RNA Cap, Translation Initiation Factor Eif4e | 0.81 | 67.0 | 5.70e-01 | 97.7% | 56.0% |
| 2bj3D02 | 3.30.70.1150 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT-like. Chain A, domain 2 | 0.72 | 42.0 | 5.24e-01 | 79.7% | 95.1% |
| 4ushA00 | 3.30.70.120 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.70 | 43.0 | 4.83e-01 | 78.9% | 78.6% |
| 2f1fA01 | 3.30.70.260 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain | 0.69 | 42.0 | 5.13e-01 | 80.5% | 100.0% |
| 4dpoB00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.69 | 51.0 | 5.69e-01 | 89.5% | 100.0% |
| 3gz7B00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.69 | 48.0 | 5.42e-01 | 81.2% | 96.9% |
| 5b08A00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.68 | 49.0 | 5.57e-01 | 82.0% | 99.0% |
| 1j2vA00 | 3.30.70.120 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.68 | 43.0 | 4.90e-01 | 77.4% | 84.2% |
| 2lqjA00 | 3.30.70.260 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain | 0.68 | 47.0 | 5.46e-01 | 90.2% | 100.0% |
| 2qyxB01 | 3.30.70.1360 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › mj0159-like | 0.68 | 42.0 | 4.61e-01 | 83.5% | 75.2% |
| 2vfrA04 | 3.30.70.2520 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.68 | 46.0 | 5.35e-01 | 76.7% | 96.8% |
| 3kkfA00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.68 | 47.0 | 5.26e-01 | 82.0% | 90.5% |
| 3fgvA00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.68 | 46.0 | 5.42e-01 | 81.2% | 100.0% |
| 4aukA01 | 3.30.70.2810 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.68 | 40.0 | 4.93e-01 | 79.7% | 97.5% |
| 2pgcA02 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.67 | 51.0 | 5.65e-01 | 95.5% | 100.0% |
| 5xzqF00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.67 | 50.0 | 5.61e-01 | 81.2% | 100.0% |
| 1tr0A00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.67 | 50.0 | 5.58e-01 | 83.5% | 98.1% |
| 2gffA00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.67 | 46.0 | 5.24e-01 | 78.2% | 95.8% |
| 3fmbA01 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.67 | 48.0 | 5.47e-01 | 79.7% | 100.0% |
| 1p1lA00 | 3.30.70.120 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.67 | 43.0 | 4.87e-01 | 78.9% | 85.3% |
| 3mcsA00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.66 | 52.0 | 4.43e-01 | 97.0% | 50.9% |
| 3bguA01 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.66 | 47.0 | 5.34e-01 | 78.2% | 100.0% |
| 2od6C00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.66 | 49.0 | 5.39e-01 | 82.0% | 95.3% |
| 5d4nC00 | 3.30.70.120 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.66 | 44.0 | 5.01e-01 | 83.5% | 90.8% |
| 3h7hB00 | 3.30.70.940 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › NusG, N-terminal domain | 0.66 | 42.0 | 4.79e-01 | 82.0% | 87.4% |
| 5k8mA02 | 3.30.70.360 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.66 | 51.0 | 5.22e-01 | 82.0% | 98.5% |
| 1lq9A00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.66 | 51.0 | 5.46e-01 | 88.7% | 95.5% |
| 4hl9A00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.66 | 45.0 | 5.21e-01 | 80.5% | 100.0% |
| 1bdfA01 | 3.30.1360.10 | Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › RNA polymerase, RBP11-like subunit | 0.65 | 41.0 | 4.51e-01 | 72.9% | 79.2% |
| 1r6yA00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.65 | 48.0 | 5.35e-01 | 82.0% | 100.0% |
| 2qycA00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.65 | 46.0 | 5.18e-01 | 82.0% | 97.1% |
| 2hhpA03 | 3.30.70.590 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Poly(A) polymerase predicted RNA binding domain | 0.64 | 53.0 | 5.09e-01 | 88.0% | 96.0% |
| 3bn7A00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.64 | 47.0 | 5.26e-01 | 81.2% | 100.0% |
| 1s7hA02 | 3.30.70.930 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.63 | 38.0 | 4.52e-01 | 81.2% | 93.9% |
| 7rsfA01 | 3.30.70.360 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.63 | 48.0 | 4.98e-01 | 78.9% | 100.0% |
| 2pokA02 | 3.30.70.360 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.63 | 48.0 | 4.49e-01 | 81.2% | 98.8% |
| 2j5aA00 | 3.30.70.60 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S6/Translation elongation factor EF1B | 0.63 | 43.0 | 4.79e-01 | 78.9% | 88.7% |
| 5xyiU00 | 3.30.70.600 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10 | 0.61 | 43.0 | 4.91e-01 | 78.9% | 100.0% |
| 3tx8A02 | 3.30.70.360 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.61 | 46.0 | 4.91e-01 | 78.9% | 100.0% |
| 8d8lF01 | 3.30.70.60 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S6/Translation elongation factor EF1B | 0.60 | 43.0 | 4.53e-01 | 78.2% | 80.5% |
| 3pfoA02 | 3.30.70.360 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.59 | 45.0 | 4.56e-01 | 78.9% | 100.0% |
| 3pfeA02 | 3.30.70.360 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.59 | 45.0 | 4.63e-01 | 81.2% | 100.0% |
| 2f7vA02 | 3.30.70.360 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.59 | 44.0 | 4.86e-01 | 78.9% | 99.1% |
| 2cg8B02 | 3.30.70.560 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK | 0.58 | 45.0 | 4.58e-01 | 83.5% | 93.2% |
| 1nz8A00 | 3.30.70.940 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › NusG, N-terminal domain | 0.57 | 43.0 | 4.51e-01 | 78.2% | 87.4% |
| 3b49A00 | 3.20.80.10 | Alpha Beta › Alpha-Beta Barrel › Multidrug-efflux Transporter 1 Regulator Bmrr; Chain A › Regulatory factor, effector binding domain | 0.56 | 47.0 | 4.15e-01 | 92.5% | 67.6% |
| 3io1A02 | 3.30.70.360 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.56 | 43.0 | 4.61e-01 | 82.0% | 98.3% |
| 4l3nA01 | 3.30.70.1840 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Spike protein, C-terminal core receptor binding subdomain | 0.56 | 41.0 | 4.03e-01 | 97.0% | 70.4% |
| 2bvfA03 | 3.40.462.20 | Alpha Beta › 3-Layer(aba) Sandwich › Vanillyl-alcohol Oxidase; Chain A, domain 3 › | 0.56 | 47.0 | 4.11e-01 | 94.0% | 84.8% |
| 1bwvA01 | 3.30.70.150 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RuBisCO large subunit, N-terminal domain | 0.56 | 47.0 | 4.80e-01 | 94.7% | 95.3% |
| 1vq3B00 | 3.30.1280.10 | Alpha Beta › 2-Layer Sandwich › Mth169; Chain: A , › Phosphoribosylformylglycinamidine synthase subunit PurS | 0.55 | 33.0 | 4.05e-01 | 78.2% | 94.0% |
| 2r7rA04 | 3.30.70.2480 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.55 | 46.0 | 4.38e-01 | 97.7% | 76.4% |
| 4mjkA00 | 3.30.70.3120 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.54 | 41.0 | 3.39e-01 | 79.7% | 96.2% |
| 4nasB01 | 3.30.70.150 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RuBisCO large subunit, N-terminal domain | 0.54 | 41.0 | 4.43e-01 | 82.0% | 98.2% |
| 3klxB00 | 3.30.530.20 | Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain | 0.53 | 44.0 | 3.98e-01 | 88.7% | 86.7% |
| 5o60I00 | 3.30.70.1730 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein L10, N-terminal RNA-binding domain | 0.53 | 42.0 | 4.34e-01 | 97.0% | 90.5% |
| 5yuyA01 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.53 | 42.0 | 4.35e-01 | 84.2% | 95.1% |
| 1ykwA01 | 3.30.70.150 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RuBisCO large subunit, N-terminal domain | 0.52 | 45.0 | 4.58e-01 | 94.7% | 96.9% |
| 5kfnA01 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.52 | 42.0 | 3.85e-01 | 86.5% | 93.8% |
| 1k8kD01 | 3.30.1460.20 | Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › | 0.52 | 38.0 | 3.65e-01 | 75.9% | 68.2% |
| 5i2cB01 | 3.30.2130.10 | Alpha Beta › 2-Layer Sandwich › VC0802-like › VC0802-like | 0.52 | 42.0 | 4.13e-01 | 88.0% | 85.6% |
| 4hvmB01 | 3.30.559.10 | Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Chloramphenicol acetyltransferase-like domain | 0.51 | 41.0 | 3.72e-01 | 87.2% | 88.3% |
| 2h6oA02 | 2.60.40.2810 | Mainly Beta › Sandwich › Immunoglobulin-like › | 0.51 | 39.0 | 3.78e-01 | 82.7% | 87.1% |
ECOD (79)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3609602 | 317.1.1.1 ↗ | a+b two layers › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › IF4E | 0.87 | 71.0 | 6.10e-01 | 97.7% | 57.4% |
| 3261320 | 317.1.1.1 ↗ | a+b two layers › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › IF4E | 0.86 | 71.0 | 6.48e-01 | 100.0% | 67.1% |
| 3355743 | 317.1.1.1 ↗ | a+b two layers › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › IF4E | 0.86 | 63.0 | 5.82e-01 | 85.7% | 61.2% |
| 4015708 | 317.1.1.0 ↗ | a+b two layers › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase | 0.85 | 70.0 | 6.03e-01 | 97.7% | 57.9% |
| 3595913 | 317.1.1.0 ↗ | a+b two layers › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase | 0.85 | 72.0 | 6.33e-01 | 100.0% | 63.2% |
| 3931549 | 317.1.1.1 ↗ | a+b two layers › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › IF4E | 0.85 | 69.0 | 6.22e-01 | 99.2% | 64.6% |
| 4227341 | 317.1.1.1 ↗ | a+b two layers › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › IF4E | 0.84 | 71.0 | 6.00e-01 | 99.2% | 56.6% |
| 3268324 | 317.1.1.1 ↗ | a+b two layers › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › IF4E | 0.84 | 70.0 | 6.35e-01 | 100.0% | 67.6% |
| 3395403 | 317.1.1.1 ↗ | a+b two layers › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › IF4E | 0.84 | 64.0 | 5.48e-01 | 87.2% | 52.8% |
| 3457076 | 317.1.1.1 ↗ | a+b two layers › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › IF4E | 0.83 | 69.0 | 5.98e-01 | 100.0% | 59.3% |
| 3894796 | 317.1.1.1 ↗ | a+b two layers › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › IF4E | 0.83 | 70.0 | 6.13e-01 | 99.2% | 62.7% |
| 3574195 | 317.1.1.1 ↗ | a+b two layers › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › IF4E | 0.83 | 70.0 | 7.14e-01 | 100.0% | 90.0% |
| 3190647 | 317.1.1.1 ↗ | a+b two layers › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › IF4E | 0.83 | 71.0 | 6.02e-01 | 100.0% | 59.0% |
| 3699127 | 317.1.1.1 ↗ | a+b two layers › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › IF4E | 0.81 | 68.0 | 5.95e-01 | 97.7% | 61.7% |
| 3511081 | 317.1.1.1 ↗ | a+b two layers › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › IF4E | 0.81 | 68.0 | 6.27e-01 | 97.0% | 70.3% |
| 3270562 | 317.1.1.1 ↗ | a+b two layers › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › IF4E | 0.79 | 67.0 | 5.88e-01 | 100.0% | 62.6% |
| 3270677 | 317.1.1.1 ↗ | a+b two layers › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › IF4E | 0.79 | 70.0 | 6.10e-01 | 100.0% | 65.3% |
| 4026074 | 317.1.1.1 ↗ | a+b two layers › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › IF4E | 0.78 | 71.0 | 6.02e-01 | 95.5% | 67.3% |
| 3237087 | 317.1.1.1 ↗ | a+b two layers › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › IF4E | 0.76 | 70.0 | 5.99e-01 | 99.2% | 64.0% |
| 4017396 | 317.1.1.1 ↗ | a+b two layers › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › IF4E | 0.75 | 71.0 | 5.83e-01 | 98.5% | 62.3% |
| 162529 | 317.1.1.1 ↗ | a+b two layers › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › IF4E | 0.75 | 65.0 | 5.44e-01 | 100.0% | 56.2% |
| 3724439 | 304.9.1.0 ↗ | a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD | 0.74 | 50.0 | 5.55e-01 | 77.4% | 86.7% |
| 4020284 | 317.1.1.1 ↗ | a+b two layers › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › IF4E | 0.72 | 67.0 | 5.56e-01 | 97.7% | 64.7% |
| 3730751 | 304.4.1.0 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel | 0.70 | 55.0 | 5.73e-01 | 94.7% | 89.5% |
| 4025874 | 304.4.1.0 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel | 0.69 | 50.0 | 5.53e-01 | 84.2% | 94.3% |
| 4022825 | 304.4.1.0 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel | 0.69 | 52.0 | 5.72e-01 | 91.7% | 100.0% |
| 4024210 | 304.4.1.0 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel | 0.68 | 53.0 | 5.57e-01 | 94.0% | 91.7% |
| 3789126 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.67 | 53.0 | 3.73e-01 | 82.0% | 49.9% |
| 3698276 | 304.4.1.0 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel | 0.66 | 54.0 | 5.60e-01 | 95.5% | 96.7% |
| 3727456 | 304.4.1.0 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel | 0.66 | 56.0 | 5.84e-01 | 96.2% | 100.0% |
| 3725131 | 304.4.1.0 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel | 0.66 | 59.0 | 5.82e-01 | 97.7% | 100.0% |
| 4949429 | 304.122.1.1 ↗ | a+b two layers › Alpha-beta plaits › Nitrogen repressor-like proteins › Nitrogen repressor-like proteins › NRD1_2 | 0.65 | 44.0 | 4.87e-01 | 84.2% | 85.7% |
| 3743252 | 304.6.1.2 ↗ | a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain › ALO | 0.65 | 57.0 | 4.48e-01 | 93.2% | 76.6% |
| 4268442 | 304.4.1.0 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel | 0.65 | 52.0 | 5.52e-01 | 96.2% | 96.5% |
| 3183608 | 304.4.1.0 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel | 0.65 | 58.0 | 4.76e-01 | 97.0% | 98.7% |
| 5059543 | 304.20.1.4 ↗ | a+b two layers › Alpha-beta plaits › PAP/Archaeal CCA-adding enzyme, C-terminal domain › PAP/Archaeal CCA-adding enzyme, C-terminal domain › CAA_C | 0.65 | 52.0 | 4.63e-01 | 86.5% | 88.4% |
| 3731573 | 304.4.1.0 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel | 0.64 | 51.0 | 5.45e-01 | 90.2% | 97.4% |
| 4642439 | 304.25.1.1 ↗ | a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain › M20_dimer | 0.64 | 46.0 | 5.13e-01 | 79.7% | 98.0% |
| 4680606 | 304.20.1.4 ↗ | a+b two layers › Alpha-beta plaits › PAP/Archaeal CCA-adding enzyme, C-terminal domain › PAP/Archaeal CCA-adding enzyme, C-terminal domain › CAA_C | 0.64 | 51.0 | 4.54e-01 | 86.5% | 86.2% |
| 3685451 | 304.4.1.0 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel | 0.63 | 54.0 | 5.24e-01 | 92.5% | 97.2% |
| 3001000 | 304.6.1.2 ↗ | a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain › ALO | 0.63 | 55.0 | 4.14e-01 | 94.0% | 75.5% |
| 1646873 | 304.6.1.2 ↗ | a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain › ALO | 0.63 | 55.0 | 4.46e-01 | 94.0% | 69.9% |
| 3736793 | 304.25.1.1 ↗ | a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain › M20_dimer | 0.62 | 48.0 | 4.44e-01 | 82.0% | 96.6% |
| 4030190 | 304.4.1.0 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel | 0.62 | 51.0 | 5.18e-01 | 88.0% | 90.2% |
| 3598039 | 304.4.1.0 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel | 0.62 | 46.0 | 5.03e-01 | 76.7% | 100.0% |
| 3958318 | 304.4.1.0 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel | 0.62 | 41.0 | 4.83e-01 | 72.2% | 100.0% |
| 4671096 | 304.4.1.54 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › Amnionless | 0.61 | 48.0 | 4.91e-01 | 86.5% | 84.6% |
| 3638246 | 304.4.1.0 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel | 0.61 | 48.0 | 4.97e-01 | 82.7% | 88.8% |
| 5022426 | 304.25.1.1 ↗ | a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain › M20_dimer | 0.61 | 47.0 | 4.98e-01 | 81.2% | 98.3% |
| 3736643 | 304.4.1.0 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel | 0.61 | 46.0 | 4.95e-01 | 79.7% | 94.5% |
| 3729608 | 304.4.1.0 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel | 0.61 | 53.0 | 5.46e-01 | 95.5% | 99.2% |
| 3718206 | 304.4.1.14 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › Dabb | 0.61 | 48.0 | 5.18e-01 | 84.2% | 100.0% |
| 4235653 | 304.25.1.1 ↗ | a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain › M20_dimer | 0.61 | 39.0 | 4.66e-01 | 77.4% | 100.0% |
| 3929632 | 304.126.1.1 ↗ | a+b two layers › Alpha-beta plaits › ferredoxin-like domain in vacuolar ATP synthase subunit C › ferredoxin-like domain in vacuolar ATP synthase subunit C › V_ATPase_I | 0.61 | 45.0 | 4.99e-01 | 94.7% | 98.1% |
| 3729211 | 304.4.1.49 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › AtuA | 0.61 | 47.0 | 5.00e-01 | 83.5% | 94.8% |
| 5026741 | 304.25.1.1 ↗ | a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain › M20_dimer | 0.60 | 48.0 | 5.02e-01 | 84.2% | 95.0% |
| 3255716 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.59 | 41.0 | 4.49e-01 | 86.5% | 88.6% |
| 3717061 | 304.107.1.5 ↗ | a+b two layers › Alpha-beta plaits › Aminomethyltransferase folate-binding domain › Aminomethyltransferase folate-binding domain › BCS1_N | 0.59 | 42.0 | 4.51e-01 | 73.7% | 94.8% |
| 3835200 | 3556.1.1.0 ↗ | a+b two layers › Uncharacterized Protein Rru_A0810 › Uncharacterized Protein Rru_A0810 › Uncharacterized Protein Rru_A0810 | 0.59 | 42.0 | 4.31e-01 | 73.7% | 87.7% |
| 1438039 | 304.44.1.1 ↗ | a+b two layers › Alpha-beta plaits › Ribosomal protein S10 › Ribosomal protein S10 › Ribosomal_S10 | 0.59 | 47.0 | 4.83e-01 | 85.7% | 91.4% |
| 4964282 | 304.25.1.1 ↗ | a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain › M20_dimer | 0.58 | 46.0 | 4.77e-01 | 84.2% | 96.0% |
| 5014271 | 304.25.1.1 ↗ | a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain › M20_dimer | 0.58 | 46.0 | 4.81e-01 | 84.2% | 96.7% |
| 3196755 | 868.1.1.2 ↗ | a+b complex topology › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › mRNA_triPase | 0.58 | 43.0 | 3.34e-01 | 78.9% | 88.7% |
| 3611915 | 304.9.1.1 ↗ | a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 | 0.57 | 42.0 | 4.24e-01 | 83.5% | 76.9% |
| 3960072 | 244.1.1.0 ↗ | a+b two layers › FAD-linked reductases, C-terminal domain-like › FAD-linked reductases-C › FAD-linked reductases-C | 0.57 | 45.0 | 4.56e-01 | 85.0% | 91.1% |
| 3604620 | 304.8.1.0 ↗ | a+b two layers › Alpha-beta plaits › ACT-like › ACT-like | 0.57 | 41.0 | 4.60e-01 | 81.2% | 100.0% |
| 4504769 | 2003.1.2.29 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › NAD_binding_8 | 0.57 | 50.0 | 3.53e-01 | 100.0% | 69.5% |
| 3278818 | 244.1.1.0 ↗ | a+b two layers › FAD-linked reductases, C-terminal domain-like › FAD-linked reductases-C › FAD-linked reductases-C | 0.57 | 45.0 | 4.55e-01 | 86.5% | 92.6% |
| 1835333 | 244.1.1.0 ↗ | a+b two layers › FAD-linked reductases, C-terminal domain-like › FAD-linked reductases-C › FAD-linked reductases-C | 0.56 | 45.0 | 4.69e-01 | 85.7% | 100.0% |
| 3735073 | 304.9.1.9 ↗ | a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_2 | 0.56 | 45.0 | 3.54e-01 | 99.2% | 40.4% |
| 3629999 | 206.1.1.7 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PI3_PI4_kinase | 0.55 | 45.0 | 3.23e-01 | 87.2% | 85.6% |
| 3943855 | 304.8.1.0 ↗ | a+b two layers › Alpha-beta plaits › ACT-like › ACT-like | 0.55 | 43.0 | 4.52e-01 | 81.2% | 96.7% |
| 3700204 | 2003.1.2.0 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain | 0.54 | 47.0 | 3.18e-01 | 96.2% | 48.8% |
| 3225950 | 304.126.1.1 ↗ | a+b two layers › Alpha-beta plaits › ferredoxin-like domain in vacuolar ATP synthase subunit C › ferredoxin-like domain in vacuolar ATP synthase subunit C › V_ATPase_I | 0.54 | 45.0 | 4.71e-01 | 94.7% | 98.3% |
| 3523342 | 304.47.1.1 ↗ | a+b two layers › Alpha-beta plaits › SEA domain › SEA domain › SEA | 0.54 | 47.0 | 4.29e-01 | 98.5% | 87.2% |
| 3638463 | 210.1.3.5 ↗ | a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases › GATase_7 | 0.52 | 41.0 | 3.28e-01 | 82.7% | 95.5% |
| 4228012 | 331.3.1.0 ↗ | a+b two layers › TBP-like › Bet v1-like › Bet v1-like | 0.52 | 38.0 | 3.68e-01 | 75.9% | 98.7% |
| 3540888 | 389.1.1.0 ↗ | few secondary structure elements › EGF-like › EGF-related › EGF/Laminin | 0.52 | 43.0 | 3.95e-01 | 88.0% | 74.1% |
| 3601760 | 244.1.1.0 ↗ | a+b two layers › FAD-linked reductases, C-terminal domain-like › FAD-linked reductases-C › FAD-linked reductases-C | 0.51 | 38.0 | 4.02e-01 | 94.0% | 87.5% |