←Back to structures
U44
Euk-VirHuman_betaherpesvirus_6A
U44__NP_042937__Human_betaherpesvirus_6A__32603
Identity
- Accession:
- NP_042937 ↗
- Protein ID:
- U44
- Kingdom:
- euk
Quality
71.8
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Roseolovirus›
Human_betaherpesvirus_6A
TaxID: 32603
Cluster
View cluster (13 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 58-166
Domain cluster:
rep: tegument_protein_UL51__YP_009052024__Elephant_endotheliotropic_herpesvirus_5__768738__D27-160
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF04533.20 best | Herpes_U44 | 138.2 | 4.20e-40 | 100.0% | 51.4% |
CATH (24)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1fewA00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.78 | 54.0 | 4.61e-01 | 71.6% | 45.7% |
| 4hyjA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.75 | 64.0 | 4.91e-01 | 91.7% | 98.7% |
| 3d19B00 | 1.20.1260.120 | Mainly Alpha › Up-down Bundle › Ferritin › Protein of unknown function DUF2935 | 0.73 | 60.0 | 4.51e-01 | 91.7% | 37.0% |
| 3m7gA02 | 1.10.8.1010 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.73 | 59.0 | 6.28e-01 | 89.0% | 97.9% |
| 7q37A01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.73 | 60.0 | 4.80e-01 | 89.0% | 100.0% |
| 7aalA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.72 | 66.0 | 4.94e-01 | 100.0% | 87.2% |
| 7p3rA01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.71 | 53.0 | 3.80e-01 | 78.9% | 71.4% |
| 6xj1A01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.71 | 61.0 | 4.68e-01 | 93.6% | 89.4% |
| 4wpeA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.70 | 60.0 | 4.53e-01 | 95.4% | 84.0% |
| 2v0oB00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.70 | 59.0 | 4.44e-01 | 92.7% | 79.3% |
| 4fzsA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.69 | 58.0 | 4.68e-01 | 90.8% | 93.8% |
| 1avoB00 | 1.20.120.180 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Proteasome activator pa28, C-terminal domain | 0.69 | 60.0 | 5.52e-01 | 95.4% | 96.4% |
| 3cazB00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.69 | 62.0 | 5.01e-01 | 100.0% | 94.8% |
| 2efkA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.69 | 61.0 | 4.68e-01 | 100.0% | 90.8% |
| 1x04A00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.69 | 60.0 | 5.01e-01 | 100.0% | 94.0% |
| 3i2wA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.68 | 62.0 | 4.69e-01 | 100.0% | 88.4% |
| 4nqiD00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.68 | 60.0 | 4.77e-01 | 100.0% | 86.2% |
| 3k29A00 | 1.10.287.1700 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.67 | 47.0 | 4.11e-01 | 72.5% | 88.2% |
| 3i9yA00 | 1.20.58.920 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.63 | 45.0 | 3.56e-01 | 78.9% | 35.8% |
| 3nrxA00 | 1.20.58.1520 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.61 | 47.0 | 4.55e-01 | 81.7% | 75.6% |
| 4errB00 | 1.20.58.1190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.61 | 40.0 | 4.47e-01 | 71.6% | 89.2% |
| 1u7lA02 | 1.20.1460.10 | Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › subunit c (vma5p) of the yeast v-atpase, domain 2 | 0.60 | 54.0 | 4.56e-01 | 100.0% | 60.1% |
| 1gqeA01 | 1.20.58.410 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Release factor | 0.59 | 44.0 | 4.44e-01 | 80.7% | 100.0% |
| 2m6bA00 | 1.20.58.390 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Neurotransmitter-gated ion-channel transmembrane domain | 0.58 | 48.0 | 4.35e-01 | 90.8% | 80.0% |
ECOD (36)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3719613 | 1189.1.1.0 ↗ | alpha bundles › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor | 0.83 | 65.0 | 5.03e-01 | 82.6% | 83.1% |
| 4473674 | 148.1.3.0 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain | 0.81 | 66.0 | 6.67e-01 | 86.2% | 94.5% |
| 3726229 | 604.1.1.58 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Helo_like_N | 0.75 | 62.0 | 5.37e-01 | 89.9% | 65.3% |
| 3257358 | 4177.1.1.8 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR_3 | 0.75 | 66.0 | 5.21e-01 | 96.3% | 88.0% |
| 3894262 | 4177.1.1.1 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH | 0.74 | 56.0 | 3.96e-01 | 78.0% | 69.5% |
| 4992667 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.74 | 54.0 | 3.83e-01 | 74.3% | 52.7% |
| 3823212 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.73 | 53.0 | 4.84e-01 | 74.3% | 79.3% |
| 3895215 | 4177.1.1.5 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › Vps5 | 0.73 | 66.0 | 5.30e-01 | 100.0% | 97.2% |
| 3739245 | 4177.1.1.14 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR_2 | 0.73 | 65.0 | 5.25e-01 | 100.0% | 90.2% |
| 4983098 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.72 | 50.0 | 4.90e-01 | 71.6% | 67.2% |
| 3770066 | 3291.1.1.169 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › KIF21A_4th | 0.71 | 47.0 | 3.85e-01 | 71.6% | 37.4% |
| 3303180 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.70 | 52.0 | 4.87e-01 | 77.1% | 74.6% |
| 4374397 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.70 | 55.0 | 5.22e-01 | 81.7% | 73.6% |
| 5079565 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.70 | 48.0 | 4.11e-01 | 70.6% | 85.7% |
| 3737139 | 4177.1.1.1 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH | 0.70 | 59.0 | 4.36e-01 | 91.7% | 77.9% |
| 3931267 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.70 | 57.0 | 5.18e-01 | 86.2% | 71.7% |
| 3655688 | 3755.3.1.303 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › KIF21A_4th | 0.70 | 49.0 | 4.19e-01 | 72.5% | 98.9% |
| 3413600 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.70 | 54.0 | 5.11e-01 | 82.6% | 69.2% |
| 3562849 | 148.1.3.254 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › KIF21A_4th | 0.70 | 47.0 | 3.63e-01 | 71.6% | 32.2% |
| 3536875 | 4177.1.1.1 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH | 0.69 | 62.0 | 4.60e-01 | 100.0% | 82.8% |
| 3599032 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.69 | 61.0 | 4.83e-01 | 100.0% | 89.1% |
| 2832211 | 4177.1.1.1 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH | 0.68 | 59.0 | 4.40e-01 | 97.2% | 79.8% |
| 4266268 | 192.8.1.376 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › RRP36 | 0.67 | 47.0 | 4.22e-01 | 71.6% | 53.3% |
| 3937673 | 4177.1.1.1 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH | 0.67 | 60.0 | 4.31e-01 | 100.0% | 78.5% |
| 3273611 | 4177.1.1.1 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH | 0.67 | 60.0 | 4.51e-01 | 100.0% | 85.8% |
| 3276938 | 4177.1.1.1 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH | 0.67 | 53.0 | 4.14e-01 | 86.2% | 84.9% |
| 3636681 | 4177.1.1.1 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH | 0.66 | 58.0 | 4.28e-01 | 100.0% | 75.5% |
| 3414779 | 4177.1.1.1 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH | 0.65 | 58.0 | 4.44e-01 | 100.0% | 83.8% |
| 3889547 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.65 | 45.0 | 3.76e-01 | 71.6% | 49.5% |
| 3402340 | 4177.1.1.1 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH | 0.65 | 58.0 | 4.35e-01 | 100.0% | 90.4% |
| 1734350 | 4177.1.1.1 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH | 0.64 | 57.0 | 4.21e-01 | 100.0% | 77.5% |
| 3709193 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.64 | 56.0 | 4.26e-01 | 100.0% | 80.7% |
| 3917938 | 4177.1.1.5 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › Vps5 | 0.64 | 57.0 | 4.60e-01 | 100.0% | 91.2% |
| 3207548 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.63 | 44.0 | 4.06e-01 | 71.6% | 86.4% |
| 5055566 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.62 | 54.0 | 5.29e-01 | 89.9% | 97.4% |
| 3714029 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.62 | 46.0 | 3.79e-01 | 78.0% | 71.1% |