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U58
Euk-VirHuman_betaherpesvirus_6A
U58__NP_042951__Human_betaherpesvirus_6A__32603
Identity
- Accession:
- NP_042951 ↗
- Protein ID:
- U58
- Kingdom:
- euk
Quality
64.2
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Roseolovirus›
Human_betaherpesvirus_6A
TaxID: 32603
Cluster
View cluster (19 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 264-360
Domain cluster:
rep: hypothetical_protein_MuHV1_gp080__YP_214088__Murid_betaherpesvirus_1__10366__D298-374
CATH (1)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5w2fA01 | 3.30.780.10 | Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor Eif1 › SUI1-like domain | 0.54 | 37.0 | 3.89e-01 | 71.1% | 86.0% |
ECOD (2)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3206162 | 306.3.1.1 ↗ | a+b two layers › Glucose permease domain IIB-like › eIF1-like › eIF1-like › SUI1 | 0.54 | 37.0 | 3.47e-01 | 71.1% | 64.8% |
| 4358354 | 2003.1.5.51 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › TPMT | 0.50 | 41.0 | 3.27e-01 | 91.8% | 53.7% |
D2
medium
residues 21-52_90-183
Domain cluster:
rep: GP87__YP_007417854__Caviid_betaherpesvirus_2__33706__D23-70_83-201
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF04532.17 best | DUF587 | 173.3 | 7.20e-51 | 75.4% | 45.8% |
| PF04532.17 | DUF587 | 44.4 | 1.80e-11 | 27.0% | 13.7% |
D3
medium
residues 53-89_184-221
Domain cluster:
representative
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF04532.17 best | DUF587 | 53.0 | 4.40e-14 | 52.0% | 16.3% |
| PF04532.17 | DUF587 | 44.5 | 1.60e-11 | 42.7% | 13.7% |
CATH (33)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 8e9gE01 | 1.10.10.1590 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › NADH-quinone oxidoreductase subunit E | 0.64 | 47.0 | 5.03e-01 | 80.0% | 100.0% |
| 1owlA02 | 1.25.40.80 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.64 | 44.0 | 3.79e-01 | 73.3% | 51.2% |
| 1d9cA00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.63 | 54.0 | 4.65e-01 | 96.0% | 82.6% |
| 3djbA01 | 1.10.472.50 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › HD-domain/PDEase-like | 0.59 | 38.0 | 3.61e-01 | 72.0% | 52.1% |
| 4mo7A02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.59 | 50.0 | 4.18e-01 | 100.0% | 81.0% |
| 4qicC01 | 1.20.140.160 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › PhyR, sigma-like (SL) domain | 0.58 | 50.0 | 4.31e-01 | 98.7% | 60.0% |
| 1xriA00 | 3.90.190.10 | Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily | 0.58 | 47.0 | 3.80e-01 | 90.7% | 95.4% |
| 4d8mA01 | 1.20.190.10 | Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain | 0.58 | 44.0 | 3.19e-01 | 81.3% | 50.0% |
| 2a2fX02 | 1.20.58.670 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Dsl1p vesicle tethering complex, Tip20p subunit, domain D | 0.57 | 44.0 | 3.76e-01 | 85.3% | 76.0% |
| 2kjgA00 | 1.20.120.970 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.57 | 40.0 | 3.74e-01 | 74.7% | 57.6% |
| 2epkX03 | 1.20.120.670 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › N-acetyl-b-d-glucoasminidase | 0.57 | 42.0 | 3.09e-01 | 81.3% | 72.3% |
| 2wvlB00 | 3.90.550.10 | Alpha Beta › Alpha-Beta Complex › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A | 0.57 | 44.0 | 2.84e-01 | 86.7% | 37.7% |
| 3axjB02 | 1.20.58.200 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 | 0.56 | 39.0 | 3.75e-01 | 72.0% | 78.8% |
| 3fblA00 | 1.20.58.800 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.55 | 38.0 | 3.79e-01 | 73.3% | 72.0% |
| 4b7hA03 | 1.20.1370.60 | Mainly Alpha › Up-down Bundle › Hemocyanin, N-terminal domain › | 0.55 | 43.0 | 3.85e-01 | 89.3% | 68.7% |
| 3g2eB00 | 3.40.920.10 | Alpha Beta › 3-Layer(aba) Sandwich › Pyruvate-ferredoxin Oxidoreductase; domain 3 › Pyruvate-ferredoxin oxidoreductase, PFOR, domain III | 0.55 | 43.0 | 3.37e-01 | 89.3% | 89.2% |
| 2w53B00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.54 | 44.0 | 3.50e-01 | 94.7% | 83.2% |
| 2lm4A01 | 1.10.150.250 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Flavinator of succinate dehydrogenase | 0.54 | 34.0 | 3.27e-01 | 76.0% | 52.2% |
| 3onkA00 | 1.25.40.90 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.54 | 42.0 | 3.50e-01 | 86.7% | 50.4% |
| 3ccyA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.53 | 44.0 | 3.68e-01 | 97.3% | 93.2% |
| 3kn6A02 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.53 | 38.0 | 2.80e-01 | 76.0% | 57.6% |
| 3pasA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.53 | 44.0 | 3.38e-01 | 96.0% | 62.6% |
| 3himA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.53 | 42.0 | 3.20e-01 | 89.3% | 66.8% |
| 1fc3B00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.52 | 41.0 | 3.79e-01 | 88.0% | 84.2% |
| 2ibdA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.52 | 42.0 | 3.50e-01 | 93.3% | 89.8% |
| 3h5qA01 | 1.20.970.10 | Mainly Alpha › Up-down Bundle › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain C | 0.52 | 40.0 | 4.16e-01 | 86.7% | 95.7% |
| 4iluA02 | 1.20.58.1290 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › CarD-like, C-terminal domain | 0.52 | 41.0 | 3.70e-01 | 92.0% | 71.2% |
| 2mabA00 | 1.10.10.1350 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Spidroin domain, C-terminal domain | 0.51 | 39.0 | 3.62e-01 | 89.3% | 86.2% |
| 1zvwA01 | 1.20.970.10 | Mainly Alpha › Up-down Bundle › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain C | 0.51 | 38.0 | 4.03e-01 | 82.7% | 98.5% |
| 3ebbA00 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.51 | 44.0 | 3.11e-01 | 100.0% | 42.8% |
| 4gtnA01 | 1.20.970.10 | Mainly Alpha › Up-down Bundle › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain C | 0.51 | 40.0 | 4.08e-01 | 89.3% | 94.6% |
| 5y6qB02 | 3.30.390.50 | Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › CO dehydrogenase flavoprotein, C-terminal domain | 0.51 | 35.0 | 3.22e-01 | 73.3% | 52.8% |
| 2genA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.51 | 41.0 | 3.20e-01 | 94.7% | 70.2% |
ECOD (20)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3962056 | 608.1.1.0 ↗ | alpha arrays › AhpD-like › AhpD-like › AhpD-like | 0.72 | 57.0 | 4.97e-01 | 84.0% | 57.3% |
| 3294636 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.66 | 47.0 | 4.10e-01 | 74.7% | 95.7% |
| 3838569 | 101.1.6.0 ↗ | alpha arrays › HTH › HTH › TrpR | 0.60 | 51.0 | 4.43e-01 | 94.7% | 68.7% |
| 3580914 | 604.12.1.2 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › Vta1 | 0.60 | 42.0 | 4.04e-01 | 73.3% | 76.5% |
| 4946659 | 101.1.10.0 ↗ | alpha arrays › HTH › HTH › Cyclin-like | 0.59 | 51.0 | 4.55e-01 | 98.7% | 80.9% |
| 5052263 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.59 | 41.0 | 4.15e-01 | 74.7% | 73.3% |
| 3853197 | 101.1.10.1 ↗ | alpha arrays › HTH › HTH › Cyclin-like › Cyclin_N | 0.58 | 47.0 | 3.68e-01 | 92.0% | 48.3% |
| 3290100 | 191.1.1.8 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › TetR_C_33 | 0.57 | 46.0 | 3.99e-01 | 94.7% | 94.6% |
| 3176126 | 4015.1.1.1 ↗ | alpha complex topology › alpha-helical domain in sec1/munc18-like (SM) proteins › alpha-helical domain in sec1/munc18-like (SM) proteins › alpha-helical domain in sec1/munc18-like (SM) proteins › Sec1 | 0.57 | 45.0 | 3.21e-01 | 93.3% | 26.8% |
| 5053357 | 101.1.10.0 ↗ | alpha arrays › HTH › HTH › Cyclin-like | 0.56 | 48.0 | 3.85e-01 | 96.0% | 56.7% |
| 3299036 | 109.4.1.883 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR+PPR_2 | 0.56 | 38.0 | 3.49e-01 | 73.3% | 53.0% |
| 3608714 | 109.4.1.420 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR | 0.55 | 39.0 | 3.45e-01 | 81.3% | 50.0% |
| 3948171 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.55 | 48.0 | 4.30e-01 | 100.0% | 80.9% |
| 3786347 | 632.10.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Coronavirus NSP7-like › Coronavirus NSP7-like | 0.55 | 38.0 | 3.90e-01 | 74.7% | 86.7% |
| 5018787 | 191.1.1.0 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain | 0.54 | 45.0 | 3.65e-01 | 100.0% | 97.6% |
| 4206339 | 109.4.1.1259 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HEAT_PBS, HEAT_2 | 0.53 | 42.0 | 2.94e-01 | 86.7% | 40.8% |
| 4971695 | 2006.1.2.0 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › DHH phosphoesterases | 0.52 | 42.0 | 3.15e-01 | 89.3% | 37.4% |
| 3519620 | 190.1.1.0 ↗ | alpha arrays › HMG-box-like › HMG-box › HMG-box | 0.51 | 36.0 | 3.24e-01 | 74.7% | 92.7% |
| 3806017 | 109.4.1.1271 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, TPR_24 | 0.51 | 40.0 | 3.35e-01 | 88.0% | 57.1% |
| 3830930 | 109.4.1.1277 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR_1, PPR_2, TPR_24 | 0.51 | 37.0 | 3.36e-01 | 81.3% | 56.2% |
D4
medium
residues 427-455_472-610