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U7

Euk-Vir

Human_betaherpesvirus_6A

U7__NP_042898__Human_betaherpesvirus_6A__32603

Identity

Accession:
NP_042898 ↗
Protein ID:
U7
Kingdom:
euk

Quality

64.3 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 14-173
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02393.22 best US22 50.0 4.40e-13 71.9% 96.0%
D2 high residues 182-315
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02393.22 best US22 38.1 2.00e-09 81.3% 91.1%
CATH (5)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1z1bA01 3.30.160.60 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Classic Zinc Finger 0.70 24.0 3.60e-01 74.6% 70.2%
4fw1A02 2.30.30.10 Mainly Beta › Roll › SH3 type barrels. › Integrase, C-terminal domain superfamily, retroviral 0.57 23.0 3.54e-01 75.4% 92.6%
3ffvA00 3.40.1580.20 Alpha Beta › 3-Layer(aba) Sandwich › SMI1/KNR4-like › Syd protein 0.55 45.0 4.08e-01 88.1% 93.4%
6bhdA03 2.30.30.140 Mainly Beta › Roll › SH3 type barrels. › 0.54 27.0 3.59e-01 78.4% 95.2%
3varA01 3.40.630.10 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Zn peptidases 0.52 45.0 3.53e-01 96.3% 92.8%
ECOD (12)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3715158 5.1.5.1 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed › WD40 0.55 40.0 2.60e-01 75.4% 29.7%
4130525 5.1.4.1 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40 0.55 41.0 2.89e-01 79.9% 43.5%
5000550 5.1.4.43 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › FG-GAP_3 0.54 40.0 2.97e-01 76.9% 70.2%
3436651 5.1.3.118 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › FBA_3 0.53 45.0 3.32e-01 91.0% 97.7%
3480502 5.1.4.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.53 39.0 2.52e-01 76.1% 19.2%
3594793 5.1.4.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.53 39.0 2.92e-01 76.1% 48.6%
3424085 5.1.3.118 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › FBA_3 0.52 43.0 3.25e-01 90.3% 82.4%
3276019 5.1.5.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed 0.51 39.0 2.68e-01 79.9% 39.8%
3275416 5.1.4.90 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Itfg2 0.50 42.0 3.12e-01 91.0% 94.2%
3631797 5.1.4.6 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40,ANAPC4_WD40 0.50 43.0 3.27e-01 91.8% 87.9%
3392175 5.1.3.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed 0.50 37.0 2.91e-01 76.1% 45.2%
3461790 5.1.3.118 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › FBA_3 0.50 43.0 3.23e-01 91.8% 85.3%
D3 high residues 379-498
PDB
D4 high residues 504-652
PDB
D5 medium residues 678-745
PDB
D6 medium residues 746-1090
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF05999.17 best Herpes_U5 532.2 1.90e-159 88.7% 70.1%
CATH (13)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2ficB00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.79 29.0 3.83e-01 73.3% 58.2%
3lxuX06 1.25.40.710 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.62 30.0 3.47e-01 92.2% 60.8%
6h2dS01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.61 33.0 4.16e-01 79.7% 82.1%
3ez0C00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.60 24.0 3.03e-01 73.9% 58.2%
2hsbA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.57 23.0 3.76e-01 87.0% 100.0%
3owaA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.55 29.0 4.01e-01 92.8% 100.0%
3jrtA00 1.20.120.1060 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.55 27.0 3.92e-01 86.1% 98.8%
3psfA03 1.10.3500.10 Mainly Alpha › Orthogonal Bundle › Tex N-terminal region-like › Tex N-terminal region-like 0.54 28.0 2.96e-01 93.9% 51.6%
6w08A01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.54 42.0 4.23e-01 79.1% 94.8%
7nmqA01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.53 43.0 4.30e-01 82.3% 95.4%
2nrjA01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.53 42.0 4.31e-01 81.2% 94.8%
4iloA00 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.52 28.0 3.37e-01 86.7% 74.6%
4ke2A00 6.10.140.1860 Special › Helix non-globular › Helix Hairpins › 0.51 22.0 2.89e-01 73.3% 68.4%
ECOD (16)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3890423 3758.1.1.0 alpha bundles › Bacterial hemolysins-like › Bacterial hemolysins › Bacterial hemolysins 0.74 34.0 3.80e-01 74.2% 54.9%
3534459 4177.1.1.1 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH 0.68 28.0 3.18e-01 73.9% 49.1%
3232473 603.1.1.97 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin, SNARE 0.66 41.0 4.93e-01 86.1% 89.6%
3393338 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.64 30.0 4.44e-01 80.0% 98.0%
3246395 603.1.1.1 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin 0.62 36.0 4.66e-01 94.8% 96.1%
3605632 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.62 28.0 3.60e-01 84.9% 70.2%
3667580 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.61 33.0 3.71e-01 79.7% 66.0%
5023516 3922.1.1.269 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Rad50_zn_hook 0.60 29.0 3.51e-01 73.3% 67.7%
3593619 603.1.1.17 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › SNARE 0.60 37.0 4.40e-01 99.4% 88.5%
4836806 1063.1.1.1 alpha complex topology › Tegument protein U14 › Tegument protein U14 › Tegument protein U14 › Herpes_pp85 0.59 49.0 4.63e-01 100.0% 72.7%
4145179 601.51.1.2 alpha bundles › Four-helical up-and-down bundle › alpha-helical domain in phase 1 flagellin › alpha-helical domain in phase 1 flagellin › Flagellin_N,Flagellin_C 0.55 33.0 3.67e-01 73.9% 72.4%
4162401 5069.1.1.4 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Ferric_reduct 0.54 33.0 4.02e-01 99.7% 90.9%
3735976 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.52 31.0 3.89e-01 100.0% 91.6%
4974861 1075.5.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter 0.51 26.0 2.89e-01 90.4% 58.5%
4029596 5001.1.1.81 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › THH1_TOM1-3_dom 0.51 28.0 3.34e-01 86.4% 75.7%
4927494 5069.1.1.0 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes 0.50 31.0 3.53e-01 72.8% 79.6%