UL21_tegument_protein

Euk-Vir

Leporid_alphaherpesvirus_4

UL21_tegument_protein__YP_009230152__Leporid_alphaherpesvirus_4__481315

Identity

77.3 mean pLDDT

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Simplexvirus› Leporid_alphaherpesvirus_4

TaxID: 481315

View cluster (29 members)

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high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 268-362

PDB

Domain cluster: rep: tegument_protein_UL21__YP_009361917__Ateline_alphaherpesvirus_1__35243__D279-385

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF03252.19 best	Herpes_UL21	47.2	2.10e-12	100.0%	17.8%

CATH (8)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
2qm8A03	1.10.287.130	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain	0.57	29.0	3.39e-01	77.9%	69.2%
6v7xB02	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.55	28.0	3.47e-01	74.7%	80.4%
1i5nB00	1.20.120.160	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain	0.55	39.0	3.60e-01	91.6%	57.3%
4mn0A00	1.10.238.10	Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › EF-hand	0.53	47.0	3.81e-01	96.8%	80.7%
1mzbA01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.53	37.0	3.93e-01	92.6%	85.4%
1jkwA02	1.10.472.10	Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like	0.52	41.0	4.04e-01	97.9%	81.2%
1aluA00	1.20.1250.10	Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; ›	0.52	42.0	3.58e-01	87.4%	72.0%
1c9bA01	1.10.472.10	Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like	0.51	37.0	3.68e-01	96.8%	76.3%

ECOD (9)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
1828353	1064.1.1.1 ↗	alpha complex topology › Tegument protein UL21 › Tegument protein UL21 › Tegument protein UL21 › Herpes_UL21	0.78	72.0	5.18e-01	100.0%	39.3%
3589353	101.1.1.11 ↗	alpha arrays › HTH › HTH › Three-helical HTH › HTH_6	0.57	35.0	3.71e-01	91.6%	68.2%
3672138	611.4.1.0 ↗	alpha bundles › N-cbl like › PG0775 C-terminal domain-like › PG0775 C-terminal domain-like	0.57	39.0	3.40e-01	85.3%	45.3%
3924927	2007.2.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › (Phosphotyrosine protein) phosphatases II › Y_phosphatase	0.53	37.0	2.66e-01	71.6%	95.8%
3971841	3552.1.1.1 ↗	alpha arrays › Pfam family PF09836 N-terminal domain › Pfam family PF09836 N-terminal domain › Pfam family PF09836 N-terminal domain › DUF2063	0.53	40.0	3.75e-01	94.7%	63.2%
4997940	186.1.1.0 ↗	alpha arrays › lambda integrase-N-like › lambda integrase-N › lambda integrase-N	0.53	45.0	4.46e-01	93.7%	92.0%
170157	4245.1.1.1 ↗	alpha duplicates or obligate multimers › SMc04008-like › SMc04008-like › SMc04008-like › DUF1244	0.53	31.0	3.17e-01	78.9%	56.1%
3268234	109.4.1.0 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat	0.52	36.0	3.17e-01	71.6%	79.3%
3724032	109.3.1.0 ↗	alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat	0.51	38.0	3.01e-01	81.1%	38.5%

D2 high residues 368-507

PDB

Domain cluster: rep: tegument_protein_UL21__YP_009252265__Canid_alphaherpesvirus_1__170325__D384-522

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF03252.19 best	Herpes_UL21	63.3	2.80e-17	93.6%	25.0%

D3 medium residues 1-51_173-224

PDB

Domain cluster: rep: tegument_protein_UL21__YP_443867__Papiine_alphaherpesvirus_2__340907__D1-51_171-191_209-225

Pfam (2)

Accession	Name	Score	E-value	Q cov	HMM cov
PF03252.19 best	Herpes_UL21	44.1	1.90e-11	51.5%	9.7%
PF03252.19	Herpes_UL21	30.7	2.10e-07	51.5%	9.5%

D4 medium residues 52-172

PDB

Domain cluster: rep: tegument_protein_UL21__YP_182374__Gallid_alphaherpesvirus_1__10386__D52-162

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF03252.19 best	Herpes_UL21	88.7	5.50e-25	100.0%	23.7%