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UL47

Euk-Vir

Anatid_alphaherpesvirus_1

UL47__YP_003084373__Anatid_alphaherpesvirus_1__104388

Identity

Accession:
YP_003084373 ↗
Protein ID:
UL47
Kingdom:
euk

Quality

64.0 mean pLDDT

Taxonomy

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Mardivirus› anatid_alphaherpesvirus_1

TaxID: 104388

Cluster

View cluster (31 members)

3D Structure

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Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 308-329_445-494
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF03362.19 best Herpes_UL47 43.8 2.20e-11 97.2% 12.1%
CATH (16)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2om6A02 1.10.150.400 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 0.68 38.0 3.70e-01 83.3% 50.6%
1cf7B00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.63 39.0 3.73e-01 73.6% 53.7%
3m1mA03 1.10.1240.50 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › 0.63 46.0 4.00e-01 77.8% 97.3%
3buxB01 1.20.930.20 Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › Adaptor protein Cbl, N-terminal domain 0.61 50.0 4.10e-01 87.5% 79.8%
6qumA04 1.10.1140.10 Mainly Alpha › Orthogonal Bundle › Bovine Mitochondrial F1-ATPase, ATP Synthase Beta Chain; Chain D, domain3 › Bovine Mitochondrial F1-atpase; Atp Synthase Beta Chain; Chain D, domain 3 0.61 53.0 4.16e-01 95.8% 52.3%
1r4gA00 1.10.8.10 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain 0.61 41.0 4.62e-01 83.3% 96.2%
1whuA00 1.10.10.400 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Polyribonucleotide nucleotidyltransferase, RNA-binding domain 0.60 39.0 3.41e-01 70.8% 45.2%
7y4rB01 1.20.1290.10 Mainly Alpha › Up-down Bundle › AhpD-like › AhpD-like 0.58 46.0 4.04e-01 94.4% 57.5%
2kjiA00 1.10.100.10 Mainly Alpha › Orthogonal Bundle › Insulin-like, subunit E › Insulin-like 0.58 36.0 4.19e-01 77.8% 92.0%
2ewfA02 1.20.1270.310 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.55 44.0 4.31e-01 88.9% 88.9%
2vwaA00 1.20.58.1330 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Plasmodium falciparum UIS3 membrane protein 0.54 44.0 3.97e-01 87.5% 91.9%
4j05A00 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.53 46.0 2.92e-01 98.6% 86.5%
2zxqA06 1.20.1270.70 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Designed single chain three-helix bundle 0.53 43.0 4.45e-01 86.1% 93.9%
4cs9C00 1.20.120.1350 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Pneumovirus matrix protein 2 (M2), zinc-binding domain 0.53 43.0 3.33e-01 90.3% 67.9%
4cs9B02 1.20.120.1350 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Pneumovirus matrix protein 2 (M2), zinc-binding domain 0.52 40.0 3.50e-01 81.9% 74.8%
2ra1A03 1.20.58.770 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.50 41.0 4.39e-01 95.8% 100.0%
ECOD (10)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3451551 101.1.10.1 ↗ alpha arrays › HTH › HTH › Cyclin-like › Cyclin_N 0.66 34.0 3.37e-01 90.3% 45.3%
3588971 6026.1.1.0 ↗ alpha duplicates or obligate multimers › cwf21 domain › cwf21 domain › cwf21 domain 0.64 42.0 4.15e-01 76.4% 64.0%
4358519 547.1.1.1 ↗ alpha duplicates or obligate multimers › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › GlutR_dimer 0.60 38.0 3.44e-01 76.4% 46.0%
3471523 3877.1.1.0 ↗ alpha bundles › Membrane protein insertase YidC-related › Membrane protein insertase YidC-related › Membrane protein insertase YidC 0.55 45.0 3.03e-01 90.3% 35.6%
4143372 148.1.3.0 ↗ alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.54 47.0 4.17e-01 100.0% 66.4%
4290897 6130.1.1.0 ↗ alpha complex topology › Selenocysteine synthase N-terminal domain › Selenocysteine synthase N-terminal domain › Selenocysteine synthase N-terminal domain 0.54 44.0 4.39e-01 94.4% 98.7%
3228982 103.1.1.86 ↗ alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain › PF28543 0.53 44.0 4.37e-01 95.8% 88.0%
3527142 524.1.1.3 ↗ alpha arrays › Ypt/Rab-GAP domain of gyp1p-like › Ypt/Rab-GAP domain of gyp1p › Ypt/Rab-GAP domain of gyp1p › RabGap-TBC_2 0.53 44.0 3.48e-01 94.4% 57.4%
3496552 190.1.1.3 ↗ alpha arrays › HMG-box-like › HMG-box › HMG-box › HMG_box_2 0.52 39.0 3.58e-01 77.8% 66.7%
3918881 190.1.1.3 ↗ alpha arrays › HMG-box-like › HMG-box › HMG-box › HMG_box_2 0.51 37.0 3.47e-01 77.8% 65.6%
D2 medium residues 330-391_689-717
PDB
Domain cluster: rep: tegument_protein_VP13_14-2__YP_010084943__Beluga_whale_alphaherpesvirus_1__1434720__D345-393_703-735
CATH (1)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2d5lA02 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.57 35.0 2.56e-01 92.3% 21.3%
ECOD (2)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3595485 2006.1.1.0 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like 0.51 32.0 2.62e-01 79.1% 32.9%
4025332 2003.1.2.24 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › Pyr_redox_2 0.51 35.0 2.38e-01 72.5% 92.1%
D3 medium residues 392-416_512-551_580-616
PDB
Domain cluster: representative
CATH (33)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1i6zA00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.81 59.0 5.29e-01 74.5% 77.0%
2i0mA01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.78 57.0 5.63e-01 75.5% 92.5%
1y1uA01 1.20.1050.20 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › STAT transcription factor, all-alpha domain 0.78 56.0 4.45e-01 74.5% 82.6%
4l8iB00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.70 50.0 4.88e-01 74.5% 98.2%
2efkA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.70 50.0 3.62e-01 74.5% 85.5%
2yf4F00 1.10.3420.10 Mainly Alpha › Orthogonal Bundle › putative ntp pyrophosphohydrolase like fold › putative ntp pyrophosphohydrolase like domain 0.68 32.0 2.84e-01 72.5% 34.3%
1s35A01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.68 48.0 4.89e-01 74.5% 100.0%
2d4uB00 1.20.120.30 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartate receptor, ligand-binding domain 0.66 48.0 4.16e-01 75.5% 67.1%
4hr1A00 1.20.1270.410 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.66 45.0 4.32e-01 70.6% 81.4%
3uumA00 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.65 46.0 4.37e-01 73.5% 85.2%
2pfdA03 1.20.120.680 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Formiminotetrahydrofolate cyclodeaminase monomer, up-and-down helical bundle 0.64 51.0 4.14e-01 87.3% 74.9%
1cunA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.63 45.0 4.53e-01 73.5% 100.0%
4yjwA00 1.20.120.930 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein PF12889, N-terminal DUF3829 0.63 46.0 3.99e-01 75.5% 61.4%
1j1jA02 1.20.58.200 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 0.62 45.0 4.85e-01 75.5% 94.1%
3h3mA00 1.20.58.380 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Flagellar protein flit. 0.62 44.0 4.75e-01 74.5% 94.4%
1dd5A01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.61 44.0 4.39e-01 75.5% 97.2%
4wzxA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.61 43.0 4.84e-01 73.5% 100.0%
1nktA04 1.10.3060.10 Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA 0.60 43.0 3.63e-01 75.5% 100.0%
1yxrA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.60 41.0 4.76e-01 71.6% 100.0%
3qa8A04 1.20.1270.250 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.59 42.0 3.24e-01 75.5% 78.1%
1gvnA00 1.10.8.130 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.58 42.0 4.55e-01 75.5% 94.3%
3pltA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.58 41.0 3.28e-01 75.5% 87.9%
1e1dA02 1.20.1270.20 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.57 42.0 4.57e-01 75.5% 91.7%
2wyhB04 1.20.1270.50 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Glycoside hydrolase family 38, central domain 0.57 41.0 4.15e-01 74.5% 89.1%
2rkhA02 1.20.1280.20 Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain 0.56 40.0 4.54e-01 76.5% 100.0%
1m6nA04 1.10.3060.10 Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA 0.56 40.0 3.69e-01 75.5% 74.8%
2mpkA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.55 39.0 4.35e-01 78.4% 100.0%
2wb7A03 1.20.120.870 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › pT26-6p, five-helical bundle domain 0.55 46.0 4.17e-01 91.2% 98.5%
2okuA00 1.20.120.470 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Acyl-CoA dehydrogenase, C-terminal domain 0.55 49.0 4.61e-01 99.0% 97.5%
4kc9A02 1.20.120.1750 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.54 47.0 3.69e-01 97.1% 69.7%
2l6jA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.53 43.0 4.19e-01 94.1% 81.1%
5fb0A02 1.20.920.10 Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like 0.51 33.0 3.24e-01 72.5% 58.9%
2l1lB00 1.20.1440.250 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.51 43.0 4.02e-01 93.1% 76.4%
ECOD (15)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3282593 4121.1.1.1 ↗ a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › CorA 0.80 60.0 4.48e-01 78.4% 74.6%
3934926 604.3.1.0 ↗ alpha bundles › Spectrin repeat-like › BAG domain › BAG domain 0.79 56.0 5.68e-01 72.5% 91.0%
3924650 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.77 55.0 5.56e-01 73.5% 96.0%
3579767 604.1.1.1 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.76 55.0 5.36e-01 74.5% 90.9%
3828970 604.3.1.1 ↗ alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › BAG 0.75 55.0 5.68e-01 75.5% 92.6%
3504306 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.73 53.0 5.32e-01 75.5% 87.6%
3217462 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.68 48.0 4.92e-01 73.5% 95.0%
3555824 4177.2.1.1 ↗ alpha duplicates or obligate multimers › BAR/IMD domain-like › Inhibitor of kappaB kinase beta dimerization domain › Inhibitor of kappaB kinase beta dimerization domain › TBK1_CCD1 0.67 49.0 3.55e-01 75.5% 76.3%
4980095 310.2.1.0 ↗ a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.64 46.0 4.59e-01 74.5% 98.1%
4295514 632.22.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.60 44.0 4.37e-01 75.5% 88.6%
4944676 632.22.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.59 42.0 4.10e-01 74.5% 95.7%
3732358 604.12.1.42 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › DUF202 0.54 37.0 3.75e-01 71.6% 86.7%
3731804 5058.1.1.37 ↗ alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › PF25886 0.53 40.0 3.60e-01 81.4% 100.0%
3574611 2004.1.1.198 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23 0.51 44.0 2.91e-01 95.1% 27.0%
4499889 192.24.1.1 ↗ alpha bundles › Long alpha-hairpin › RPC62 helical hairpin domain › RPC62 helical hairpin domain › RPC3_helical 0.50 38.0 4.00e-01 79.4% 100.0%
D4 medium residues 495-511_552-579_617-688
PDB
Domain cluster: rep: UL47_tegument_protein_IE_transactivator__YP_009230180__Leporid_alphaherpesvirus_4__481315__D470-578
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF03362.19 best Herpes_UL47 54.4 1.40e-14 82.9% 14.3%
CATH (1)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1fewA00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.57 46.0 4.04e-01 86.3% 72.8%
ECOD (1)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5046568 604.12.1.0 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.75 53.0 4.61e-01 72.6% 71.8%