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US22_family_homolog

Euk-Vir

Murid_betaherpesvirus_1

US22_family_homolog__YP_214143__Murid_betaherpesvirus_1__10366

Identity

Accession:
YP_214143 ↗
Protein ID:
US22_family_homolog
Kingdom:
euk

Quality

67.9 mean pLDDT

Taxonomy

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Muromegalovirus› Murid_betaherpesvirus_1

TaxID: 10366

Cluster

View cluster (59 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 172-278
PDB
Domain cluster: rep: US22_family_homolog__YP_214055__Murid_betaherpesvirus_1__10366__D433-537
CATH (20)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2ymsC00 2.40.10.480 Mainly Beta › Beta Barrel › Thrombin, subunit H › 0.61 40.0 4.72e-01 72.0% 96.0%
2digA00 2.30.30.140 Mainly Beta › Roll › SH3 type barrels. › 0.60 29.0 3.54e-01 71.0% 70.6%
4fw1A02 2.30.30.10 Mainly Beta › Roll › SH3 type barrels. › Integrase, C-terminal domain superfamily, retroviral 0.60 28.0 3.82e-01 91.6% 87.0%
3ijcA00 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.60 42.0 2.89e-01 72.0% 23.8%
6u5uG07 3.30.1120.100 Alpha Beta › 2-Layer Sandwich › Arylsulfatase, C-terminal domain › 0.60 43.0 4.02e-01 74.8% 83.3%
2gu1A01 3.10.450.350 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.59 43.0 4.66e-01 76.6% 97.7%
5m8cB01 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.58 46.0 3.24e-01 85.0% 49.3%
3dueA00 3.40.1420.30 Alpha Beta › 3-Layer(aba) Sandwich › Inhibitor of vertebrate lysozyme, Ivy › 0.56 42.0 3.98e-01 78.5% 75.6%
3tu3B01 3.30.720.80 Alpha Beta › 2-Layer Sandwich › Signal recognition particle alu RNA binding heterodimer, srp9/1 › 0.56 27.0 3.17e-01 75.7% 63.2%
3of7A00 2.130.10.30 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II 0.54 47.0 3.15e-01 97.2% 87.9%
7c9rH01 3.90.50.10 Alpha Beta › Alpha-Beta Complex › Photosynthetic Reaction Center; Chain H, domain 2 › Photosynthetic Reaction Center, subunit H, domain 2 0.54 42.0 3.76e-01 83.2% 69.6%
1qftB00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.54 44.0 3.79e-01 100.0% 56.2%
1a2pA00 3.10.450.30 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › Microbial ribonucleases 0.53 43.0 4.34e-01 100.0% 86.1%
3pqhA01 2.20.220.20 Mainly Beta › Single Sheet › Glycosyl hydrolase fold › 0.53 28.0 3.40e-01 93.5% 85.0%
5ic7A00 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.53 45.0 3.19e-01 94.4% 93.5%
2v1rA00 2.30.30.40 Mainly Beta › Roll › SH3 type barrels. › SH3 Domains 0.52 31.0 3.75e-01 92.5% 94.0%
1rwiA00 2.120.10.30 Mainly Beta › 6 Propeller › Neuraminidase › TolB, C-terminal domain 0.52 46.0 3.49e-01 97.2% 78.1%
3c5mA00 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.51 44.0 3.04e-01 96.3% 91.8%
3jamg01 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.50 43.0 3.12e-01 94.4% 55.5%
6m90A02 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.50 45.0 3.29e-01 100.0% 83.7%
ECOD (33)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3660755 4.8.1.21 ↗ beta barrels › SH3 › Chromo domain-like › Chromo domain-like › PTM_DIR17_Tudor 0.68 32.0 3.81e-01 82.2% 65.3%
3709353 64.1.1.1 ↗ beta meanders › WW domain-like › WW domain › WW domain › WW 0.66 32.0 4.29e-01 72.9% 94.0%
3660003 5.1.10.8 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 12-bladed › ANAPC4_WD40 0.66 44.0 5.02e-01 71.0% 91.3%
3936589 5.1.5.1 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed › WD40 0.63 44.0 2.95e-01 72.0% 30.0%
3579710 5.1.10.0 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 12-bladed 0.61 42.0 4.29e-01 71.0% 90.5%
3505046 5.1.2.2 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 5-bladed › WD40 0.61 44.0 4.29e-01 94.4% 69.6%
1114686 4.1.1.8 ↗ beta barrels › SH3 › SH3 › SH3 › IN_DBD_C 0.60 29.0 3.83e-01 93.5% 85.7%
3953498 4.1.1.439 ↗ beta barrels › SH3 › SH3 › SH3 › PF26205 0.56 34.0 4.02e-01 86.9% 88.0%
3511200 389.1.2.0 ↗ few secondary structure elements › EGF-like › EGF-related › Complement control module/SCR domain 0.56 38.0 4.23e-01 100.0% 87.1%
3924096 5.1.4.102 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40_3 0.54 47.0 3.42e-01 96.3% 88.7%
3466257 5.1.3.142 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › Beta-prop_AT5G49610-like 0.54 48.0 3.35e-01 98.1% 90.4%
3356146 5.1.4.323 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40, Beta-prop_WDR75_1st 0.54 48.0 3.33e-01 100.0% 94.6%
3514791 5.1.4.1 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40 0.53 47.0 3.22e-01 97.2% 58.1%
1107292 5.1.4.53 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › DUF4784 0.53 48.0 3.49e-01 100.0% 94.0%
3940221 5.1.5.76 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed › WD40, Beta-prop_NOL10_N 0.53 47.0 3.37e-01 100.0% 94.3%
3380688 5.1.3.67 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › FBA_1 0.53 43.0 3.16e-01 88.8% 94.5%
3224154 5.1.4.304 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Beta-prop_WDR11_2nd 0.52 48.0 3.33e-01 100.0% 85.5%
3596935 5.1.4.0 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.52 47.0 3.29e-01 97.2% 63.4%
3414211 109.54.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 › C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 0.52 48.0 2.84e-01 100.0% 33.5%
4093354 4.1.1.1 ↗ beta barrels › SH3 › SH3 › SH3 › SH3_1 0.52 31.0 3.68e-01 92.5% 90.0%
3390746 5.1.3.19 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › Hira 0.52 44.0 3.62e-01 90.7% 74.1%
3895602 5.1.4.102 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40_3 0.52 46.0 3.34e-01 97.2% 85.1%
None — 0.52 46.0 3.34e-01 97.2% 70.5%
3223450 5.1.4.1 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40 0.52 45.0 3.09e-01 96.3% 95.8%
4121453 5.1.4.172 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Beta-prop_CAF1B_HIR1 0.52 46.0 2.83e-01 100.0% 45.5%
3390301 5.1.4.102 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40_3 0.52 45.0 3.29e-01 96.3% 87.1%
3935168 5.1.3.0 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed 0.52 45.0 3.32e-01 94.4% 62.2%
3104388 5.1.5.92 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed › WD40, Beta-prop_EML 0.51 46.0 3.19e-01 100.0% 74.0%
3479291 5.1.5.67 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed › Beta-prop_WDR19_2nd 0.51 44.0 3.16e-01 97.2% 88.5%
4025576 5.1.4.0 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.51 45.0 3.40e-01 95.3% 57.1%
3999383 5.1.4.1 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40 0.51 46.0 3.24e-01 100.0% 77.3%
3741358 5.1.4.0 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.50 45.0 3.45e-01 97.2% 76.6%
3810782 5.1.5.37 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed › DUF295 0.50 44.0 3.12e-01 97.2% 59.4%
D2 medium residues 12-171_279-322_335-356
PDB
Domain cluster: rep: e141__YP_007016528__Murid_betaherpesvirus_8__1261657__D1-155_323-396
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02393.22 best US22 44.1 2.90e-11 50.4% 97.6%
CATH (6)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4ld1A00 2.60.450.20 Mainly Beta › Sandwich › lipopolysaccharide transport protein A fold › 0.60 23.0 2.71e-01 74.8% 47.1%
2in5A00 2.40.360.10 Mainly Beta › Beta Barrel › YmcC-like fold › YmcC-like 0.56 32.0 3.39e-01 91.2% 62.6%
2ogqA01 3.30.1120.30 Alpha Beta › 2-Layer Sandwich › Arylsulfatase, C-terminal domain › POLO box domain 0.53 26.0 3.27e-01 83.2% 77.8%
4by2B00 2.60.450.20 Mainly Beta › Sandwich › lipopolysaccharide transport protein A fold › 0.52 23.0 2.71e-01 77.0% 57.4%
2l33A00 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.52 22.0 3.28e-01 80.5% 93.4%
4dsdA00 3.40.1420.30 Alpha Beta › 3-Layer(aba) Sandwich › Inhibitor of vertebrate lysozyme, Ivy › 0.50 27.0 3.42e-01 74.3% 88.9%
ECOD (4)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3700776 292.2.1.0 ↗ a+b two layers › RIP/Polo-box domain › Polo-box domain › Polo-box domain 0.71 19.0 3.54e-01 75.7% 75.7%
3504473 77.3.1.0 ↗ beta meanders › open-sided beta-meander › CPAP G-box domain › CPAP G-box domain 0.62 23.0 2.64e-01 74.8% 41.7%
4609923 77.3.1.4 ↗ beta meanders › open-sided beta-meander › CPAP G-box domain › CPAP G-box domain › PF28998 0.53 23.0 2.92e-01 83.6% 65.9%
3231343 77.1.1.10 ↗ beta meanders › open-sided beta-meander › Outer surface protein › Outer surface protein › PF28998 0.52 23.0 2.94e-01 83.6% 68.5%