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Uracil-DNA_glycosylase
Euk-VirChrysochromulina_ericina_virus
Uracil-DNA_glycosylase__YP_009173284__Chrysochromulina_ericina_virus__455364
Identity
- Accession:
- YP_009173284 ↗
- Protein ID:
- Uracil-DNA_glycosylase
- Kingdom:
- euk
Quality
91.2
mean pLDDT
Taxonomy
Bamfordvirae›
Nucleocytoviricota›
Megaviricetes›
Algavirales›
Phycodnaviridae›
Chrysochromulina_ericina_virus
TaxID: 455364
Cluster
View cluster (62 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 45-214
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF03167.26 best | UDG | 61.6 | 1.20e-16 | 97.7% | 96.4% |
CATH (43)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 6lydA01 | 3.40.470.10 | Alpha Beta › 3-Layer(aba) Sandwich › Uracil-DNA Glycosylase, subunit E › Uracil-DNA glycosylase-like domain | 0.96 | 94.0 | 7.99e-01 | 100.0% | 76.5% |
| 2booA00 | 3.40.470.10 | Alpha Beta › 3-Layer(aba) Sandwich › Uracil-DNA Glycosylase, subunit E › Uracil-DNA glycosylase-like domain | 0.94 | 90.0 | 7.90e-01 | 100.0% | 72.6% |
| 2c53A00 | 3.40.470.10 | Alpha Beta › 3-Layer(aba) Sandwich › Uracil-DNA Glycosylase, subunit E › Uracil-DNA glycosylase-like domain | 0.92 | 88.0 | 7.76e-01 | 100.0% | 72.8% |
| 2c2pA01 | 3.40.470.10 | Alpha Beta › 3-Layer(aba) Sandwich › Uracil-DNA Glycosylase, subunit E › Uracil-DNA glycosylase-like domain | 0.70 | 64.0 | 6.44e-01 | 99.4% | 98.8% |
| 2l3fA00 | 3.40.470.10 | Alpha Beta › 3-Layer(aba) Sandwich › Uracil-DNA Glycosylase, subunit E › Uracil-DNA glycosylase-like domain | 0.69 | 59.0 | 6.11e-01 | 99.4% | 96.9% |
| 1mugA00 | 3.40.470.10 | Alpha Beta › 3-Layer(aba) Sandwich › Uracil-DNA Glycosylase, subunit E › Uracil-DNA glycosylase-like domain | 0.68 | 61.0 | 6.24e-01 | 98.8% | 99.4% |
| 1wywA00 | 3.40.470.10 | Alpha Beta › 3-Layer(aba) Sandwich › Uracil-DNA Glycosylase, subunit E › Uracil-DNA glycosylase-like domain | 0.68 | 63.0 | 5.84e-01 | 100.0% | 82.4% |
| 5t3uB00 | 3.40.50.510 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Phosphotransferase system, mannose-type IIA component | 0.65 | 43.0 | 4.79e-01 | 95.3% | 85.0% |
| 3fojA00 | 3.40.250.10 | Alpha Beta › 3-Layer(aba) Sandwich › Oxidized Rhodanese; domain 1 › Rhodanese-like domain | 0.64 | 31.0 | 3.94e-01 | 84.7% | 76.8% |
| 2fqxA01 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.64 | 45.0 | 5.07e-01 | 95.3% | 93.1% |
| 3p9zA01 | 3.40.50.10090 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.63 | 36.0 | 4.73e-01 | 92.4% | 100.0% |
| 3hh8A02 | 3.40.50.1980 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nitrogenase molybdenum iron protein domain | 0.62 | 41.0 | 4.61e-01 | 95.3% | 87.0% |
| 1duvG01 | 3.40.50.1370 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Aspartate/ornithine carbamoyltransferase | 0.62 | 39.0 | 4.18e-01 | 94.1% | 71.3% |
| 4qdiA03 | 3.90.190.20 | Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Mur ligase, C-terminal domain | 0.61 | 35.0 | 3.84e-01 | 100.0% | 66.4% |
| 2be7A01 | 3.40.50.1370 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Aspartate/ornithine carbamoyltransferase | 0.58 | 37.0 | 3.92e-01 | 94.7% | 71.5% |
| 3kzhB00 | 3.40.1190.20 | Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase | 0.58 | 51.0 | 4.14e-01 | 95.3% | 85.0% |
| 3kcnB00 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.57 | 40.0 | 4.38e-01 | 93.5% | 89.1% |
| 1s8nA01 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.55 | 39.0 | 4.29e-01 | 92.9% | 91.7% |
| 4hvlA00 | 3.40.50.200 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Peptidase S8/S53 domain | 0.55 | 45.0 | 3.56e-01 | 87.6% | 82.7% |
| 3c2qA02 | 3.40.50.10690 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › putative lor/sdh protein like domains | 0.54 | 47.0 | 4.24e-01 | 94.1% | 86.3% |
| 1xfkA00 | 3.40.800.10 | Alpha Beta › 3-Layer(aba) Sandwich › Arginase; Chain A › Ureohydrolase domain | 0.54 | 43.0 | 3.53e-01 | 84.7% | 52.2% |
| 3okpA01 | 3.40.50.2000 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; | 0.54 | 48.0 | 4.62e-01 | 94.7% | 99.5% |
| 3l8hA00 | 3.40.50.1000 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like | 0.54 | 47.0 | 4.68e-01 | 94.1% | 100.0% |
| 2cb0A02 | 3.40.50.10490 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 | 0.54 | 38.0 | 4.02e-01 | 93.5% | 80.3% |
| 5aykA04 | 3.40.30.10 | Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin | 0.54 | 32.0 | 3.96e-01 | 99.4% | 96.1% |
| 5vipB01 | 3.90.226.10 | Alpha Beta › Alpha-Beta Complex › 2-enoyl-CoA Hydratase; Chain A, domain 1 › 2-enoyl-CoA Hydratase; Chain A, domain 1 | 0.54 | 39.0 | 3.61e-01 | 75.3% | 88.4% |
| 3k1zA01 | 3.40.50.1000 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like | 0.53 | 45.0 | 4.66e-01 | 92.9% | 100.0% |
| 4rcnA04 | 3.90.226.10 | Alpha Beta › Alpha-Beta Complex › 2-enoyl-CoA Hydratase; Chain A, domain 1 › 2-enoyl-CoA Hydratase; Chain A, domain 1 | 0.52 | 39.0 | 3.53e-01 | 76.5% | 90.6% |
| 3p9pA03 | 3.40.50.880 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Class I glutamine amidotransferase (GATase) domain | 0.52 | 41.0 | 4.29e-01 | 94.7% | 90.9% |
| 7ec2A01 | 3.40.50.2000 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; | 0.52 | 40.0 | 4.19e-01 | 95.9% | 88.7% |
| 3d6jA01 | 3.40.50.1000 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like | 0.52 | 41.0 | 4.40e-01 | 88.8% | 99.3% |
| 6l25A00 | 3.20.20.140 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Metal-dependent hydrolases | 0.52 | 43.0 | 3.85e-01 | 91.2% | 98.4% |
| 3vthA03 | 3.30.420.360 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › | 0.52 | 35.0 | 4.14e-01 | 98.8% | 99.2% |
| 3umoA00 | 3.40.1190.20 | Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase | 0.52 | 45.0 | 3.72e-01 | 94.7% | 87.1% |
| 1xrsB02 | 3.40.50.280 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Cobalamin-binding domain | 0.52 | 40.0 | 4.14e-01 | 92.9% | 87.5% |
| 7zs9401 | 3.40.50.410 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › von Willebrand factor, type A domain | 0.51 | 43.0 | 3.95e-01 | 90.0% | 100.0% |
| 6ldqA01 | 3.40.50.2000 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; | 0.51 | 44.0 | 4.38e-01 | 92.9% | 100.0% |
| 3c85A00 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.51 | 38.0 | 4.03e-01 | 91.8% | 86.0% |
| 3pf6A00 | 6.10.250.2290 | Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.51 | 18.0 | 3.04e-01 | 74.7% | 90.0% |
| 2p9jB00 | 3.40.50.1000 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like | 0.51 | 43.0 | 4.42e-01 | 93.5% | 95.1% |
| 4dyvA00 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.50 | 44.0 | 4.07e-01 | 93.5% | 95.3% |
| 4r33A00 | 3.20.20.70 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I | 0.50 | 43.0 | 3.39e-01 | 94.1% | 96.6% |
| 4e94A01 | 3.40.50.10740 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Murein tetrapeptidase LD-carboxypeptidase, N-terminal domain | 0.50 | 42.0 | 4.32e-01 | 90.6% | 96.8% |
ECOD (42)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2100092 | 7569.1.1.1 ↗ | a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG | 0.96 | 93.0 | 7.65e-01 | 100.0% | 68.5% |
| 3837322 | 7569.1.1.1 ↗ | a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG | 0.95 | 91.0 | 7.65e-01 | 100.0% | 64.2% |
| 4168074 | 7569.1.1.1 ↗ | a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG | 0.95 | 92.0 | 7.97e-01 | 100.0% | 70.4% |
| 3171107 | 7569.1.1.1 ↗ | a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG | 0.92 | 90.0 | 7.37e-01 | 100.0% | 67.4% |
| 3592251 | 7569.1.1.0 ↗ | a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like | 0.92 | 89.0 | 7.81e-01 | 100.0% | 72.3% |
| 4621405 | 7569.1.1.1 ↗ | a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG | 0.91 | 89.0 | 7.60e-01 | 100.0% | 78.3% |
| 4149039 | 7569.1.1.1 ↗ | a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG | 0.88 | 85.0 | 7.51e-01 | 100.0% | 75.2% |
| 4499054 | 7569.1.1.1 ↗ | a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG | 0.85 | 82.0 | 7.25e-01 | 100.0% | 75.2% |
| 2129698 | 7569.1.1.1 ↗ | a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG | 0.78 | 72.0 | 6.24e-01 | 97.6% | 75.9% |
| 3789320 | 7569.1.1.1 ↗ | a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG | 0.70 | 64.0 | 5.74e-01 | 97.6% | 96.0% |
| 3287862 | 7569.1.1.1 ↗ | a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG | 0.68 | 60.0 | 5.96e-01 | 97.1% | 92.0% |
| 4265071 | 7570.1.1.1 ↗ | a/b three-layered sandwiches › MurD-like peptide ligases, peptide-binding domain › MurD-like peptide ligases, peptide-binding domain › MurD-like peptide ligases, peptide-binding domain › Mur_ligase_C | 0.66 | 38.0 | 4.20e-01 | 98.8% | 69.6% |
| 4581422 | 7588.1.1.2 ↗ | a/b three-layered sandwiches › NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase › NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase › NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase › NadA | 0.64 | 30.0 | 3.74e-01 | 83.5% | 70.5% |
| 4318327 | 2007.1.4.2 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Phosphofructokinase N-terminal domain › DAGK_cat | 0.62 | 42.0 | 4.91e-01 | 92.9% | 99.2% |
| 4535746 | 2007.1.14.1 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Chelatase-like › Oxidored_nitro | 0.59 | 41.0 | 4.05e-01 | 94.7% | 66.1% |
| 4502617 | 2007.1.4.3 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Phosphofructokinase N-terminal domain › NAD_kinase | 0.58 | 33.0 | 4.10e-01 | 92.4% | 92.0% |
| 4945910 | 2003.1.14.2 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › Aspartate/ornithine carbamoyltransferase › OTCace_N | 0.58 | 35.0 | 3.68e-01 | 87.6% | 65.3% |
| 4982125 | 2002.1.1.67 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Pro_dh | 0.54 | 40.0 | 3.46e-01 | 75.9% | 77.4% |
| 4356781 | 7512.1.1.13 ↗ | a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › PS_pyruv_trans | 0.54 | 39.0 | 3.95e-01 | 74.7% | 84.6% |
| 5081078 | 7512.1.1.30 ↗ | a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_4 | 0.54 | 47.0 | 4.59e-01 | 94.1% | 100.0% |
| 3941904 | 2006.1.4.18 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › PIN7 | 0.54 | 36.0 | 4.21e-01 | 77.6% | 96.7% |
| 4933298 | 3787.2.1.0 ↗ | alpha bundles › HAD superfamily helical bundle insertion domain | 0.53 | 46.0 | 3.56e-01 | 94.1% | 93.8% |
| 3955024 | 2006.1.1.0 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like | 0.52 | 45.0 | 4.42e-01 | 94.1% | 94.2% |
| 2627935 | 2002.1.1.44 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › TatD_DNase | 0.52 | 43.0 | 3.85e-01 | 91.2% | 98.4% |
| 3948792 | 2007.1.1.4 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Class I glutamine amidotransferase-like › Peptidase_S66 | 0.52 | 42.0 | 4.27e-01 | 90.6% | 89.1% |
| 4181909 | 2003.1.8.4 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › MurCD/PglD N-terminal domain-like › MurD-like_N | 0.52 | 29.0 | 3.64e-01 | 72.9% | 92.0% |
| 5000511 | 2006.1.4.3 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › NYN | 0.52 | 40.0 | 4.09e-01 | 88.8% | 83.5% |
| 5049985 | 2006.1.4.3 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › NYN | 0.52 | 42.0 | 4.50e-01 | 88.2% | 98.7% |
| 3622045 | 2007.1.4.3 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Phosphofructokinase N-terminal domain › NAD_kinase | 0.51 | 41.0 | 4.19e-01 | 94.1% | 87.3% |
| 5035356 | 2006.1.4.3 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › NYN | 0.51 | 42.0 | 4.04e-01 | 89.4% | 94.5% |
| 5073238 | 2006.1.1.13 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Acid_PPase | 0.51 | 43.0 | 4.50e-01 | 91.8% | 100.0% |
| 4460501 | 7510.1.1.3 ↗ | a/b three-layered sandwiches › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like › FA_synthesis | 0.51 | 40.0 | 4.26e-01 | 93.5% | 93.5% |
| 5044880 | 2006.1.1.18 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › HAD_2 | 0.51 | 44.0 | 4.08e-01 | 94.1% | 96.8% |
| 3742866 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.51 | 31.0 | 3.74e-01 | 94.7% | 96.2% |
| 4985743 | 2006.1.1.0 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like | 0.51 | 43.0 | 4.50e-01 | 92.9% | 97.5% |
| 4974804 | 7512.1.1.139 ↗ | a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › DUF1972 | 0.50 | 41.0 | 4.14e-01 | 87.6% | 97.1% |
| 3819842 | 2006.1.4.3 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › NYN | 0.50 | 42.0 | 4.20e-01 | 87.1% | 96.5% |
| 5059537 | 2007.2.2.1 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › Phosphotyrosine protein phosphatases I-like › LMWPc | 0.50 | 39.0 | 4.30e-01 | 93.5% | 99.3% |
| 3520053 | 7590.1.1.3 ↗ | a/b three-layered sandwiches › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs › Piwi,ArgoMid | 0.50 | 37.0 | 3.72e-01 | 93.5% | 74.3% |
| 3970128 | 2002.1.1.0 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels | 0.50 | 42.0 | 3.74e-01 | 91.8% | 98.4% |
| 3331148 | 2006.1.4.3 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › NYN | 0.50 | 44.0 | 4.36e-01 | 94.7% | 89.4% |
| 5038903 | 2006.1.4.13 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › PIN_9 | 0.50 | 37.0 | 4.14e-01 | 94.7% | 97.0% |