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VITF-3_45kda_subunit

Euk-Vir

NY_014_poxvirus

VITF-3_45kda_subunit__YP_009408523__NY_014_poxvirus__2025360

Identity

Accession:
YP_009408523 ↗
Protein ID:
VITF-3_45kda_subunit
Kingdom:
euk

Quality

88.9 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 125-180
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF05718.18 best Pox_int_trans 92.8 2.70e-26 100.0% 14.9%
CATH (45)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3gjyA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.72 42.0 2.64e-01 78.6% 11.5%
5eowA00 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.70 52.0 3.18e-01 100.0% 12.7%
6h5bB01 3.30.450.30 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › Dynein light chain 2a, cytoplasmic 0.65 54.0 4.37e-01 98.2% 65.5%
1j3wC00 3.30.450.30 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › Dynein light chain 2a, cytoplasmic 0.62 53.0 4.10e-01 98.2% 61.7%
1ifqB00 3.30.450.50 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › Longin domain 0.61 54.0 4.15e-01 100.0% 58.6%
1y7bA01 2.115.10.20 Mainly Beta › 5 Propeller › Tachylectin-2; Chain A › Glycosyl hydrolase domain; family 43 0.60 50.0 3.17e-01 98.2% 97.2%
2j3tD01 3.30.450.70 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › 0.60 54.0 4.06e-01 100.0% 58.2%
2ovsA00 2.40.128.380 Mainly Beta › Beta Barrel › Lipocalin › T3SS negative regulator GrlR 0.60 43.0 3.41e-01 76.8% 51.7%
5mc9A02 2.60.120.200 Mainly Beta › Sandwich › Jelly Rolls › 0.60 42.0 2.88e-01 92.9% 22.5%
7ct3A01 3.30.450.30 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › Dynein light chain 2a, cytoplasmic 0.59 53.0 4.16e-01 100.0% 69.2%
3lidA03 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.59 51.0 4.28e-01 96.4% 83.3%
1h8mA00 3.30.450.50 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › Longin domain 0.59 52.0 3.87e-01 100.0% 57.1%
2p4bB02 3.30.200.100 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › MucB/RseB, C-terminal domain 0.58 45.0 3.79e-01 100.0% 49.0%
4ew7A00 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.58 51.0 4.09e-01 100.0% 83.2%
2j3tC00 3.30.450.70 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › 0.58 51.0 3.84e-01 100.0% 60.3%
5bmnA04 3.30.310.50 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › Alpha-D-phosphohexomutase, C-terminal domain 0.58 51.0 4.46e-01 98.2% 75.9%
3cueC00 3.30.450.70 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › 0.58 52.0 3.83e-01 100.0% 54.5%
3kyeA00 3.30.450.30 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › Dynein light chain 2a, cytoplasmic 0.57 46.0 3.80e-01 98.2% 65.5%
2e8yA02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.57 43.0 3.58e-01 80.4% 58.9%
2ovrB02 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.57 47.0 3.00e-01 100.0% 97.9%
2dmwA01 3.30.450.50 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › Longin domain 0.57 50.0 3.95e-01 100.0% 56.0%
2wylC00 3.60.15.10 Alpha Beta › 4-Layer Sandwich › Metallo-beta-lactamase; Chain A › Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 0.56 50.0 3.15e-01 100.0% 47.0%
1pbyA03 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.55 40.0 3.74e-01 100.0% 60.5%
1tm0A02 3.10.310.10 Alpha Beta › Roll › Diaminopimelate Epimerase; Chain A, domain 1 › Diaminopimelate Epimerase; Chain A, domain 1 0.55 45.0 3.36e-01 92.9% 100.0%
1jssA00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.55 48.0 3.31e-01 100.0% 70.4%
8es5A01 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.55 48.0 3.62e-01 100.0% 70.3%
3a4yA01 3.60.15.10 Alpha Beta › 4-Layer Sandwich › Metallo-beta-lactamase; Chain A › Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 0.55 46.0 3.10e-01 100.0% 60.6%
2xa7M01 3.30.450.60 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › 0.54 49.0 3.79e-01 100.0% 57.5%
5z5dA02 2.60.120.200 Mainly Beta › Sandwich › Jelly Rolls › 0.54 41.0 2.79e-01 82.1% 51.3%
4xpmB00 3.40.1840.10 Alpha Beta › 3-Layer(aba) Sandwich › Profilin-like › YNR034W-A-like 0.53 47.0 4.45e-01 100.0% 97.0%
2f7lA04 3.30.310.50 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › Alpha-D-phosphohexomutase, C-terminal domain 0.53 45.0 4.03e-01 100.0% 76.5%
3eweA01 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.52 38.0 2.55e-01 80.4% 22.4%
2h7fX02 3.90.15.10 Alpha Beta › Alpha-Beta Complex › Topoisomerase I; Chain A, domain 3 › Topoisomerase I; Chain A, domain 3 0.52 40.0 2.75e-01 87.5% 93.8%
5nslA01 2.115.10.20 Mainly Beta › 5 Propeller › Tachylectin-2; Chain A › Glycosyl hydrolase domain; family 43 0.52 39.0 2.38e-01 85.7% 23.6%
1a41A01 3.90.15.10 Alpha Beta › Alpha-Beta Complex › Topoisomerase I; Chain A, domain 3 › Topoisomerase I; Chain A, domain 3 0.51 37.0 3.04e-01 83.9% 74.8%
2kheA00 3.30.2310.20 Alpha Beta › 2-Layer Sandwich › YaeB-like fold › RelE-like 0.51 41.0 3.63e-01 94.6% 88.8%
3kw2A01 2.40.240.20 Mainly Beta › Beta Barrel › Ribosomal Protein L25; Chain P › Hypothetical PUA domain-like; domain 1 0.51 41.0 3.97e-01 100.0% 88.2%
2jjdF02 3.90.190.10 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily 0.51 42.0 2.84e-01 100.0% 21.8%
1g8jB00 2.102.10.10 Mainly Beta › 3-layer Sandwich › Rieske Iron-sulfur Protein › Rieske [2Fe-2S] iron-sulphur domain 0.51 40.0 3.24e-01 94.6% 95.3%
4jgpA02 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.51 42.0 3.59e-01 100.0% 77.8%
1nrkA01 3.30.70.1630 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.51 44.0 3.69e-01 98.2% 59.8%
2kd2A01 2.40.128.180 Mainly Beta › Beta Barrel › Lipocalin › 0.50 42.0 3.73e-01 96.4% 83.3%
2nqwA00 3.30.465.10 Alpha Beta › 2-Layer Sandwich › Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 › 0.50 43.0 3.81e-01 100.0% 97.7%
3k44B00 3.30.2450.30 Alpha Beta › 2-Layer Sandwich › Secreted effector protein pipB2 fold › 0.50 44.0 3.32e-01 100.0% 49.3%
3kd4A03 2.60.120.1130 Mainly Beta › Sandwich › Jelly Rolls › 0.50 42.0 3.26e-01 100.0% 55.5%
ECOD (74)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4948154 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.65 56.0 4.37e-01 98.2% 62.4%
5065158 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.65 56.0 4.18e-01 100.0% 53.3%
3782257 874.1.1.0 a+b duplicates or obligate multimers › Smc hinge domain › Smc hinge domain › Smc hinge domain 0.64 44.0 2.94e-01 85.7% 17.8%
4977402 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.64 52.0 4.03e-01 98.2% 55.2%
4927242 223.2.1.62 a+b three layers › Profilin-like › profilin-like › profilin-like › DUF6659 0.63 53.0 4.26e-01 98.2% 71.4%
5049438 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.63 56.0 4.16e-01 100.0% 56.4%
4928701 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.63 55.0 4.46e-01 96.4% 79.0%
5077119 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.63 55.0 4.06e-01 100.0% 49.3%
3231733 223.2.1.8 a+b three layers › Profilin-like › profilin-like › profilin-like › Sybindin 0.62 55.0 4.12e-01 100.0% 57.9%
None 0.62 53.0 3.19e-01 98.2% 100.0%
4975569 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.62 54.0 4.19e-01 98.2% 58.4%
5076775 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.62 55.0 4.20e-01 100.0% 60.0%
4948242 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.62 54.0 4.00e-01 100.0% 51.3%
3490407 5.1.4.1 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40 0.62 53.0 3.21e-01 100.0% 97.3%
3691605 244.1.1.0 a+b two layers › FAD-linked reductases, C-terminal domain-like › FAD-linked reductases-C › FAD-linked reductases-C 0.62 52.0 4.01e-01 98.2% 41.5%
4980071 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.62 54.0 4.20e-01 100.0% 59.2%
3460642 223.2.1.8 a+b three layers › Profilin-like › profilin-like › profilin-like › Sybindin 0.61 54.0 4.03e-01 100.0% 57.3%
5049111 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.61 54.0 4.17e-01 100.0% 58.4%
3688807 244.1.1.0 a+b two layers › FAD-linked reductases, C-terminal domain-like › FAD-linked reductases-C › FAD-linked reductases-C 0.61 51.0 4.11e-01 98.2% 47.0%
5044703 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.61 54.0 4.22e-01 100.0% 60.8%
3173088 223.2.1.19 a+b three layers › Profilin-like › profilin-like › profilin-like › Intu_longin_1 0.61 54.0 3.90e-01 100.0% 57.5%
4928263 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.61 54.0 4.31e-01 100.0% 75.5%
3734451 244.1.1.0 a+b two layers › FAD-linked reductases, C-terminal domain-like › FAD-linked reductases-C › FAD-linked reductases-C 0.60 52.0 3.82e-01 100.0% 64.4%
3686555 244.1.1.0 a+b two layers › FAD-linked reductases, C-terminal domain-like › FAD-linked reductases-C › FAD-linked reductases-C 0.60 50.0 3.70e-01 98.2% 33.8%
4945857 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.60 53.0 4.10e-01 100.0% 60.0%
3825338 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.60 53.0 4.00e-01 100.0% 49.6%
5074371 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.60 52.0 3.91e-01 100.0% 52.4%
5051729 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.60 51.0 3.77e-01 100.0% 53.8%
3715965 223.2.1.8 a+b three layers › Profilin-like › profilin-like › profilin-like › Sybindin 0.60 52.0 3.82e-01 98.2% 60.0%
None 0.60 52.0 3.83e-01 100.0% 66.5%
5026576 331.1.1.0 a+b two layers › TBP-like › TATA-box binding protein-like › TATA-box binding protein-like 0.59 53.0 4.60e-01 100.0% 72.9%
3166618 223.2.1.8 a+b three layers › Profilin-like › profilin-like › profilin-like › Sybindin 0.59 53.0 3.81e-01 100.0% 57.2%
3705571 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.59 52.0 3.88e-01 100.0% 46.9%
4926979 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.59 51.0 4.06e-01 98.2% 70.4%
3707662 223.2.1.42 a+b three layers › Profilin-like › profilin-like › profilin-like › Synaptobrevin 0.59 52.0 3.74e-01 100.0% 41.2%
5077954 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.59 51.0 3.94e-01 100.0% 59.2%
2755908 223.2.1.8 a+b three layers › Profilin-like › profilin-like › profilin-like › Sybindin 0.58 51.0 3.78e-01 98.2% 58.6%
4945423 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.58 52.0 4.23e-01 100.0% 70.5%
4997750 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.58 51.0 3.87e-01 100.0% 60.7%
6873 223.2.1.15 a+b three layers › Profilin-like › profilin-like › profilin-like › Longin 0.58 51.0 3.81e-01 100.0% 57.1%
4028834 223.2.1.7 a+b three layers › Profilin-like › profilin-like › profilin-like › SRP-alpha_N 0.58 51.0 3.99e-01 100.0% 57.5%
3931143 223.2.1.7 a+b three layers › Profilin-like › profilin-like › profilin-like › SRP-alpha_N 0.58 51.0 3.95e-01 100.0% 56.0%
3243753 223.2.1.8 a+b three layers › Profilin-like › profilin-like › profilin-like › Sybindin 0.57 51.0 3.81e-01 100.0% 60.7%
5050119 331.10.2.0 a+b two layers › TBP-like › S-adenosylmethionine decarboxylase-related › Bacterial S-adenosylmethionine decarboxylase 0.57 50.0 4.29e-01 98.2% 74.4%
5014673 1.1.13.0 beta barrels › cradle loop barrel › RIFT-related › Phage tail proteins 0.57 49.0 4.39e-01 98.2% 95.0%
3267300 223.2.1.7 a+b three layers › Profilin-like › profilin-like › profilin-like › SRP-alpha_N 0.57 50.0 3.86e-01 100.0% 53.1%
5001058 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.57 50.0 3.77e-01 100.0% 63.6%
3432113 223.2.1.7 a+b three layers › Profilin-like › profilin-like › profilin-like › SRP-alpha_N 0.57 50.0 3.88e-01 100.0% 58.4%
5044876 331.10.2.0 a+b two layers › TBP-like › S-adenosylmethionine decarboxylase-related › Bacterial S-adenosylmethionine decarboxylase 0.57 49.0 4.37e-01 98.2% 83.7%
3782077 223.2.1.8 a+b three layers › Profilin-like › profilin-like › profilin-like › Sybindin 0.57 50.0 3.66e-01 100.0% 61.9%
4977778 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.57 49.0 3.96e-01 100.0% 64.3%
4929825 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.57 46.0 3.78e-01 98.2% 67.2%
3689291 220.1.1.69 beta barrels › PH domain-like › PH domain-like › PH domain-like › Meiotic_rec114 0.56 49.0 3.60e-01 100.0% 72.9%
4945126 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.56 50.0 3.82e-01 100.0% 63.1%
3247669 207.1.1.81 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › FTH 0.56 48.0 3.16e-01 100.0% 32.4%
3701193 223.2.1.8 a+b three layers › Profilin-like › profilin-like › profilin-like › Sybindin 0.56 50.0 3.72e-01 100.0% 56.2%
3738706 320.1.1.0 a+b two layers › R3H domain-like › R3H domain › R3H domain 0.56 46.0 3.74e-01 98.2% 48.3%
3175956 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.56 50.0 3.72e-01 100.0% 50.7%
3697589 223.1.1.94 a+b three layers › Profilin-like › sensor domains › sensor domains › PAS-like 0.56 49.0 3.84e-01 100.0% 82.5%
4271433 246.3.1.1 a+b four layers › Carbon-nitrogen hydrolase-like › DNase I-like › DNase I-like › Exo_endo_phos 0.55 46.0 3.07e-01 100.0% 98.8%
3502276 331.2.1.1 a+b two layers › TBP-like › Phosphoglucomutase, C-terminal domain › Phosphoglucomutase, C-terminal domain › PGM_PMM_IV 0.55 47.0 4.14e-01 98.2% 74.1%
4927372 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.55 47.0 3.82e-01 100.0% 80.0%
3482975 223.2.1.7 a+b three layers › Profilin-like › profilin-like › profilin-like › SRP-alpha_N 0.55 48.0 3.72e-01 100.0% 56.0%
4946890 331.2.1.0 a+b two layers › TBP-like › Phosphoglucomutase, C-terminal domain › Phosphoglucomutase, C-terminal domain 0.54 47.0 4.04e-01 98.2% 71.1%
4977323 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.54 42.0 3.53e-01 100.0% 44.8%
3409172 331.23.1.3 a+b two layers › TBP-like › Integrator IntS9/IntS11 C-terminal domain › Integrator IntS9/IntS11 C-terminal domain › IntS11_C 0.53 46.0 4.03e-01 98.2% 76.5%
5035567 331.2.1.1 a+b two layers › TBP-like › Phosphoglucomutase, C-terminal domain › Phosphoglucomutase, C-terminal domain › PGM_PMM_IV 0.53 45.0 4.28e-01 100.0% 95.7%
5030737 331.2.1.1 a+b two layers › TBP-like › Phosphoglucomutase, C-terminal domain › Phosphoglucomutase, C-terminal domain › PGM_PMM_IV 0.53 45.0 3.91e-01 98.2% 72.2%
4939738 331.2.1.1 a+b two layers › TBP-like › Phosphoglucomutase, C-terminal domain › Phosphoglucomutase, C-terminal domain › PGM_PMM_IV 0.53 45.0 3.96e-01 98.2% 75.3%
4951845 331.2.1.1 a+b two layers › TBP-like › Phosphoglucomutase, C-terminal domain › Phosphoglucomutase, C-terminal domain › PGM_PMM_IV 0.53 42.0 3.94e-01 96.4% 70.7%
5050853 2004.1.1.16 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Arf 0.52 38.0 2.51e-01 80.4% 17.5%
4995617 331.2.1.1 a+b two layers › TBP-like › Phosphoglucomutase, C-terminal domain › Phosphoglucomutase, C-terminal domain › PGM_PMM_IV 0.51 44.0 3.87e-01 100.0% 75.3%
4940833 331.2.1.1 a+b two layers › TBP-like › Phosphoglucomutase, C-terminal domain › Phosphoglucomutase, C-terminal domain › PGM_PMM_IV 0.51 43.0 3.80e-01 98.2% 74.1%
4087169 331.2.1.1 a+b two layers › TBP-like › Phosphoglucomutase, C-terminal domain › Phosphoglucomutase, C-terminal domain › PGM_PMM_IV 0.51 43.0 3.77e-01 100.0% 73.3%
D2 medium residues 1-111_186-225
PDB
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF05718.18 best Pox_int_trans 140.3 1.00e-40 74.8% 30.1%
PF05718.18 Pox_int_trans 72.9 3.00e-20 27.2% 10.5%
D3 medium residues 297-381
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF05718.18 best Pox_int_trans 136.1 1.80e-39 98.8% 22.0%