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VP1
Euk-VirNorovirus_GII.17
VP1__YP_009518836__Norovirus_GII.17__552592
Identity
- Accession:
- YP_009518836 ↗
- Protein ID:
- VP1
- Kingdom:
- euk
Quality
83.3
mean pLDDT
Taxonomy
Orthornavirae›
Pisuviricota›
Pisoniviricetes›
Picornavirales›
Caliciviridae›
Norovirus›
Norovirus_GII.17
TaxID: 552592
Cluster
View cluster (17 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 50-215
Domain cluster:
rep: structural_polyprotein__YP_009333175__Bastrovirus-like_virus_VietNam_Bat_17819_21__1906170__D141-305
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00915.27 best | Calici_coat | 191.3 | 2.50e-56 | 100.0% | 55.1% |
| PF00073.27 | Rhv | 34.1 | 3.00e-08 | 78.9% | 57.3% |
D2
medium
residues 230-282_396-533
Domain cluster:
rep: VP1__YP_009679035__Norovirus_GII_Hu_JP_2007_GII.P15_GII.15_Sapporo_HK299__1529918__D230-281_420-543
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF08435.18 best | Calici_coat_C | 251.7 | 9.40e-75 | 95.8% | 62.6% |
D3
medium
residues 283-395
Domain cluster:
rep: VP1_capsid_protein__YP_009679041__Norovirus_dog_GVI.1_HKU_Ca026F_2007_HKG__673457__D281-384
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF08435.18 best | Calici_coat_C | 67.8 | 1.50e-18 | 81.4% | 38.3% |
CATH (35)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 6j0qA02 | 2.40.30.120 | Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Positive stranded ssRNA viruses | 0.93 | 87.0 | 8.91e-01 | 97.3% | 100.0% |
| 3q39B02 | 2.40.30.120 | Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Positive stranded ssRNA viruses | 0.92 | 87.0 | 8.87e-01 | 97.3% | 100.0% |
| 4qv2A02 | 2.40.30.120 | Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Positive stranded ssRNA viruses | 0.87 | 83.0 | 8.22e-01 | 100.0% | 97.5% |
| 2zl7A02 | 2.40.30.120 | Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Positive stranded ssRNA viruses | 0.87 | 67.0 | 7.46e-01 | 97.3% | 100.0% |
| 4rlzA02 | 2.40.30.120 | Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Positive stranded ssRNA viruses | 0.86 | 81.0 | 8.26e-01 | 97.3% | 100.0% |
| 5e6tA02 | 2.40.30.120 | Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Positive stranded ssRNA viruses | 0.86 | 69.0 | 7.54e-01 | 97.3% | 100.0% |
| 3lq6A02 | 2.40.30.120 | Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Positive stranded ssRNA viruses | 0.85 | 79.0 | 7.91e-01 | 97.3% | 100.0% |
| 4rdlA02 | 2.40.30.120 | Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Positive stranded ssRNA viruses | 0.83 | 75.0 | 7.69e-01 | 97.3% | 100.0% |
| 3op1A02 | 2.40.30.30 | Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Riboflavin kinase-like | 0.68 | 58.0 | 5.90e-01 | 100.0% | 91.9% |
| 1fuiA03 | 3.20.14.10 | Alpha Beta › Alpha-Beta Barrel › L-fucose Isomerase; Chain A, domain 3 › L-fucose/L-arabinose isomerase, C-terminal | 0.66 | 59.0 | 4.48e-01 | 95.6% | 72.1% |
| 3w1eA03 | 2.40.10.410 | Mainly Beta › Beta Barrel › Thrombin, subunit H › FlgT, C-terminal domain | 0.66 | 49.0 | 5.46e-01 | 91.2% | 98.9% |
| 2qcpX01 | 2.40.50.320 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Copper binding periplasmic protein CusF | 0.63 | 35.0 | 4.21e-01 | 98.2% | 82.7% |
| 1n08A00 | 2.40.30.30 | Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Riboflavin kinase-like | 0.61 | 51.0 | 4.66e-01 | 100.0% | 68.2% |
| 4n0rA03 | 2.60.40.3950 | Mainly Beta › Sandwich › Immunoglobulin-like › | 0.60 | 45.0 | 4.59e-01 | 95.6% | 80.9% |
| 4dyoA02 | 2.30.250.10 | Mainly Beta › Roll › Aminopeptidase i, Domain 2 › Aminopeptidase i, Domain 2 | 0.60 | 52.0 | 4.84e-01 | 93.8% | 100.0% |
| 1vwxB02 | 2.40.30.10 | Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Translation factors | 0.59 | 54.0 | 4.60e-01 | 100.0% | 81.7% |
| 1vq8B02 | 2.40.30.10 | Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Translation factors | 0.58 | 53.0 | 5.00e-01 | 99.1% | 89.8% |
| 1a7sA01 | 2.40.10.10 | Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases | 0.58 | 40.0 | 4.05e-01 | 83.2% | 71.4% |
| 3rd4B00 | 2.40.50.660 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › | 0.58 | 36.0 | 4.18e-01 | 97.3% | 86.6% |
| 7ylrA01 | 2.40.30.10 | Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Translation factors | 0.57 | 49.0 | 5.04e-01 | 93.8% | 100.0% |
| 3buuB00 | 2.50.20.10 | Mainly Beta › Clam › outer membrane lipoprotein receptor (LolB), chain A › Lipoprotein localisation LolA/LolB/LppX | 0.57 | 40.0 | 3.22e-01 | 72.6% | 94.5% |
| 3s98A03 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.55 | 37.0 | 4.04e-01 | 96.5% | 84.9% |
| 1si5H01 | 2.40.10.10 | Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases | 0.54 | 43.0 | 4.24e-01 | 84.1% | 100.0% |
| 2zgcA01 | 2.40.10.10 | Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases | 0.54 | 42.0 | 4.09e-01 | 82.3% | 96.0% |
| 2vpaA00 | 2.30.110.10 | Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A | 0.54 | 43.0 | 3.55e-01 | 85.0% | 63.7% |
| 1xhnA01 | 2.30.110.10 | Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A | 0.54 | 42.0 | 3.75e-01 | 85.0% | 75.3% |
| 2eddA01 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.53 | 37.0 | 3.73e-01 | 95.6% | 71.4% |
| 2wstA00 | 2.60.90.10 | Mainly Beta › Sandwich › Adenovirus Type 5 Fiber Protein (Receptor Binding Domain) › Adenovirus pIV-related, attachment domain | 0.53 | 46.0 | 3.98e-01 | 96.5% | 75.6% |
| 6rptC00 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.51 | 39.0 | 3.92e-01 | 96.5% | 81.2% |
| 3hvnA01 | 3.90.840.10 | Alpha Beta › Alpha-Beta Complex › HIV-1 Reverse Transcriptase; Chain A, domain 3 › Thiol-activated cytolysin superfamily/Thiol-activated cytolysin, alpha-beta domain | 0.51 | 37.0 | 3.27e-01 | 76.1% | 62.2% |
| 1uenA00 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.51 | 37.0 | 3.65e-01 | 96.5% | 70.4% |
| 1wfoA01 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.51 | 35.0 | 3.66e-01 | 95.6% | 77.9% |
| 5fahA01 | 2.40.10.10 | Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases | 0.50 | 38.0 | 3.79e-01 | 89.4% | 76.1% |
| 1gvzA01 | 2.40.10.10 | Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases | 0.50 | 40.0 | 3.91e-01 | 89.4% | 78.5% |
| 5e55B02 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.50 | 34.0 | 3.69e-01 | 96.5% | 86.0% |
ECOD (27)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2505866 | 1.2.1.4 ↗ | beta barrels › cradle loop barrel › Capsid protein protrusion (P) domain › Capsid protein protrusion (P) domain › Calici_coat, Calici_coat_C | 0.94 | 72.0 | 6.45e-01 | 78.8% | 62.8% |
| 2505880 | 1.2.1.2 ↗ | beta barrels › cradle loop barrel › Capsid protein protrusion (P) domain › Capsid protein protrusion (P) domain › Calici_coat_C | 0.94 | 74.0 | 6.66e-01 | 85.8% | 63.0% |
| 2505848 | 1.2.1.2 ↗ | beta barrels › cradle loop barrel › Capsid protein protrusion (P) domain › Capsid protein protrusion (P) domain › Calici_coat_C | 0.93 | 90.0 | 8.04e-01 | 100.0% | 79.7% |
| 2553941 | 10.2.1.43 ↗ | beta sandwiches › jelly-roll › Nucleoplasmin-like/VP (viral coat and capsid proteins) › Nucleoplasmin-like/VP (viral coat and capsid proteins) › Calici_coat_C | 0.92 | 89.0 | 6.17e-01 | 100.0% | 36.4% |
| 4881921 | 10.2.1.14 ↗ | beta sandwiches › jelly-roll › Nucleoplasmin-like/VP (viral coat and capsid proteins) › Nucleoplasmin-like/VP (viral coat and capsid proteins) | 0.86 | 81.0 | 5.72e-01 | 100.0% | 36.7% |
| 2505857 | 1.2.1.2 ↗ | beta barrels › cradle loop barrel › Capsid protein protrusion (P) domain › Capsid protein protrusion (P) domain › Calici_coat_C | 0.84 | 75.0 | 6.94e-01 | 100.0% | 77.2% |
| 2126884 | 10.2.1.43 ↗ | beta sandwiches › jelly-roll › Nucleoplasmin-like/VP (viral coat and capsid proteins) › Nucleoplasmin-like/VP (viral coat and capsid proteins) › Calici_coat_C | 0.84 | 80.0 | 5.60e-01 | 100.0% | 49.8% |
| 4881922 | 1.2.1.2 ↗ | beta barrels › cradle loop barrel › Capsid protein protrusion (P) domain › Capsid protein protrusion (P) domain › Calici_coat_C | 0.84 | 74.0 | 6.87e-01 | 100.0% | 77.2% |
| 1696469 | 10.2.1.43 ↗ | beta sandwiches › jelly-roll › Nucleoplasmin-like/VP (viral coat and capsid proteins) › Nucleoplasmin-like/VP (viral coat and capsid proteins) › Calici_coat_C | 0.82 | 76.0 | 5.48e-01 | 100.0% | 37.9% |
| 2171578 | 1.2.1.2 ↗ | beta barrels › cradle loop barrel › Capsid protein protrusion (P) domain › Capsid protein protrusion (P) domain › Calici_coat_C | 0.82 | 78.0 | 7.19e-01 | 99.1% | 81.8% |
| 4856093 | 10.2.1.43 ↗ | beta sandwiches › jelly-roll › Nucleoplasmin-like/VP (viral coat and capsid proteins) › Nucleoplasmin-like/VP (viral coat and capsid proteins) › Calici_coat_C | 0.81 | 73.0 | 7.14e-01 | 100.0% | 89.9% |
| 4872941 | 10.2.1.43 ↗ | beta sandwiches › jelly-roll › Nucleoplasmin-like/VP (viral coat and capsid proteins) › Nucleoplasmin-like/VP (viral coat and capsid proteins) › Calici_coat_C | 0.80 | 71.0 | 7.01e-01 | 93.8% | 92.4% |
| 1695947 | 10.2.1.14 ↗ | beta sandwiches › jelly-roll › Nucleoplasmin-like/VP (viral coat and capsid proteins) › Nucleoplasmin-like/VP (viral coat and capsid proteins) | 0.80 | 72.0 | 5.08e-01 | 100.0% | 34.7% |
| 3740846 | 1.1.7.46 ↗ | beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › SMUBP-2_HCS1_1B | 0.68 | 58.0 | 5.83e-01 | 95.6% | 89.6% |
| 3240679 | 1.1.7.0 ↗ | beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C | 0.66 | 60.0 | 5.28e-01 | 97.3% | 69.4% |
| 115 | 1.1.7.18 ↗ | beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › Fucose_iso_C | 0.66 | 58.0 | 4.55e-01 | 95.6% | 76.3% |
| 3703044 | 1.1.7.10 ↗ | beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › Flavokinase | 0.66 | 60.0 | 5.24e-01 | 99.1% | 76.4% |
| 3924486 | 2004.1.1.184 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_11 | 0.65 | 58.0 | 3.82e-01 | 100.0% | 55.1% |
| 4171511 | 1.1.7.10 ↗ | beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › Flavokinase | 0.62 | 56.0 | 4.76e-01 | 100.0% | 64.7% |
| 3190862 | 1.1.7.0 ↗ | beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C | 0.62 | 54.0 | 5.29e-01 | 95.6% | 100.0% |
| 1108154 | 12.1.1.41 ↗ | beta sandwiches › Glycosyl hydrolase domain-like › Glycosyl hydrolase domain › Glycosyl hydrolase domain › DUF5605 | 0.60 | 45.0 | 4.62e-01 | 95.6% | 82.4% |
| 5033844 | 71.1.1.8 ↗ | beta meanders › Lipoprotein localization factors LolAB › Lipoprotein localization factors LolAB › Lipoprotein localization factors LolAB › LolA_like | 0.57 | 40.0 | 3.17e-01 | 72.6% | 94.2% |
| 3213122 | 4184.1.1.0 ↗ | beta barrels › MFPT repeat › MFPT repeat › MFPT repeat | 0.55 | 41.0 | 4.27e-01 | 95.6% | 85.7% |
| 3331566 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.51 | 40.0 | 4.01e-01 | 95.6% | 83.5% |
| 4003995 | 10.32.1.0 ↗ | beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like | 0.51 | 41.0 | 3.79e-01 | 88.5% | 83.3% |
| 3884372 | 11.1.1.711 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › FN3_IL27B_N | 0.50 | 33.0 | 3.52e-01 | 89.4% | 76.0% |
| 3938968 | 10.32.1.4 ↗ | beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like › EMP24_GP25L | 0.50 | 35.0 | 3.56e-01 | 95.6% | 72.2% |