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VP1_protein
Euk-VirTasmanian_aquabirnavirus
VP1_protein__YP_009177609__Tasmanian_aquabirnavirus__1721090
Identity
- Accession:
- YP_009177609 ↗
- Protein ID:
- VP1_protein
- Kingdom:
- euk
Quality
70.4
mean pLDDT
Cluster
View cluster (6 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 112-180
Domain cluster:
rep: RNA-dependent_RNA_polymerase__YP_010086266__Lates_calcarifer_birnavirus__2583366__D125-188
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF04197.18 best | Birna_RdRp_palm | 97.4 | 1.40e-27 | 100.0% | 13.4% |
D2
medium
residues 181-209_241-256_308-357_397-433_451-514
Domain cluster:
rep: VP1_RNA-dependent_RNA_polymerase__NP_690839__Infectious_bursal_disease_virus__10995__D189-259_308-337_421-491
Pfam (3)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF04197.18 best | Birna_RdRp_palm | 188.2 | 4.50e-55 | 52.0% | 22.2% |
| PF04197.18 | Birna_RdRp_palm | 77.5 | 1.50e-21 | 27.6% | 10.2% |
| PF04197.18 | Birna_RdRp_palm | 31.0 | 1.80e-07 | 15.8% | 5.5% |
D3
medium
residues 257-307_434-450
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF04197.18 best | Birna_RdRp_palm | 66.2 | 3.90e-18 | 76.5% | 10.5% |
CATH (14)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3zgxA02 | 6.10.140.1720 | Special › Helix non-globular › Helix Hairpins › | 0.63 | 44.0 | 4.03e-01 | 73.5% | 81.3% |
| 3fbzA01 | 1.20.58.800 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.59 | 49.0 | 4.27e-01 | 91.2% | 65.7% |
| 4h63K00 | 1.10.287.3490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.59 | 40.0 | 3.60e-01 | 70.6% | 71.4% |
| 3vhlA02 | 1.20.58.740 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › DOCK DHR2 domain, lobe C | 0.59 | 51.0 | 4.24e-01 | 97.1% | 91.7% |
| 4hojA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.58 | 50.0 | 4.43e-01 | 100.0% | 92.2% |
| 4i43B02 | 3.30.43.40 | Alpha Beta › 2-Layer Sandwich › Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 › Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding domain | 0.56 | 49.0 | 4.10e-01 | 95.6% | 89.5% |
| 3d8lA00 | 1.10.8.940 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Uncharacterised protein, phage p2 ORF12 | 0.56 | 43.0 | 3.87e-01 | 80.9% | 61.5% |
| 1jr8A00 | 1.20.120.310 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › ERV/ALR sulfhydryl oxidase domain | 0.56 | 48.0 | 4.20e-01 | 98.5% | 77.1% |
| 3ppuB02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.55 | 47.0 | 4.08e-01 | 100.0% | 82.3% |
| 2p6vA00 | 1.20.120.1110 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › TAFH/NHR1 domain | 0.54 | 46.0 | 4.16e-01 | 95.6% | 96.9% |
| 2kxpA01 | 3.30.1140.60 | Alpha Beta › 2-Layer Sandwich › Ribosomal protein S3 C-terminal domain › F-actin capping protein, alpha subunit | 0.54 | 45.0 | 3.86e-01 | 91.2% | 88.8% |
| 4ks9A01 | 1.20.140.90 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Malonyl-CoA decarboxylase, oligemerization domain | 0.53 | 44.0 | 3.72e-01 | 97.1% | 80.2% |
| 1a41A02 | 1.20.120.380 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Type 1-topoisomerase catalytic fragment, domain 2 | 0.53 | 45.0 | 4.10e-01 | 97.1% | 97.9% |
| 1f81A00 | 1.20.1020.10 | Mainly Alpha › Up-down Bundle › CREB-binding Protein; Chain A › TAZ domain | 0.51 | 43.0 | 3.94e-01 | 91.2% | 95.4% |
ECOD (11)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| None | — | 0.94 | 89.0 | 5.14e-01 | 100.0% | 38.7% | |
| 1145898 | 304.48.2.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › 'palm' domain in birnaviruse RNA-dependent RNA polymerase › Birna_RdRp_palm | 0.94 | 89.0 | 5.12e-01 | 100.0% | 37.8% |
| 3289266 | 4995.1.1.0 ↗ | alpha arrays › Methionine synthase domain-like › Methionine synthase domain-like › Methionine synthase domain-like | 0.62 | 52.0 | 4.81e-01 | 91.2% | 90.6% |
| 3688567 | 109.4.1.88 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › MUN | 0.60 | 51.0 | 2.94e-01 | 94.1% | 20.2% |
| 3989810 | 3291.1.1.5 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Relaxase_C | 0.59 | 40.0 | 3.60e-01 | 97.1% | 50.5% |
| 3638639 | 1128.1.1.1 ↗ | alpha bundles › LYR protein › LYR protein › LYR protein › Complex1_LYR | 0.57 | 42.0 | 3.71e-01 | 77.9% | 85.0% |
| 3705197 | 574.1.1.1 ↗ | alpha bundles › Surp module (SWAP domain) › Surp module (SWAP domain) › Surp module (SWAP domain) › Surp | 0.55 | 41.0 | 3.54e-01 | 80.9% | 58.2% |
| 3309351 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.54 | 45.0 | 3.49e-01 | 94.1% | 41.9% |
| 3700138 | 574.1.1.1 ↗ | alpha bundles › Surp module (SWAP domain) › Surp module (SWAP domain) › Surp module (SWAP domain) › Surp | 0.53 | 41.0 | 4.13e-01 | 85.3% | 87.1% |
| 3850519 | 109.4.1.172 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › MMS19_C | 0.53 | 45.0 | 2.91e-01 | 98.5% | 22.1% |
| 3274262 | 101.1.2.460 ↗ | alpha arrays › HTH › HTH › winged helix domain › WHD_DDX60 | 0.50 | 38.0 | 3.45e-01 | 82.4% | 74.7% |
D4
medium
residues 358-396_515-582
Domain cluster:
representative
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF20488.4 best | Birna_VP1_thumb | 83.3 | 2.50e-23 | 56.1% | 35.9% |
| PF04197.18 | Birna_RdRp_palm | 46.4 | 3.90e-12 | 49.5% | 7.2% |
CATH (12)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1zuyA00 | 2.30.30.40 | Mainly Beta › Roll › SH3 type barrels. › SH3 Domains | 0.53 | 25.0 | 3.13e-01 | 98.1% | 75.9% |
| 1yn8A00 | 2.30.30.40 | Mainly Beta › Roll › SH3 type barrels. › SH3 Domains | 0.53 | 24.0 | 2.99e-01 | 96.3% | 69.5% |
| 1zuuA00 | 2.30.30.40 | Mainly Beta › Roll › SH3 type barrels. › SH3 Domains | 0.52 | 25.0 | 3.08e-01 | 96.3% | 76.8% |
| 2v1qA00 | 2.30.30.40 | Mainly Beta › Roll › SH3 type barrels. › SH3 Domains | 0.52 | 24.0 | 3.00e-01 | 96.3% | 71.7% |
| 3i35A00 | 2.30.30.40 | Mainly Beta › Roll › SH3 type barrels. › SH3 Domains | 0.51 | 24.0 | 2.99e-01 | 96.3% | 73.7% |
| 3m8eA00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.51 | 31.0 | 3.19e-01 | 100.0% | 63.4% |
| 1tbxB00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.51 | 29.0 | 3.16e-01 | 99.1% | 64.4% |
| 1eupA00 | 1.10.630.10 | Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 | 0.51 | 41.0 | 2.88e-01 | 91.6% | 63.8% |
| 6vlfA03 | 2.30.30.40 | Mainly Beta › Roll › SH3 type barrels. › SH3 Domains | 0.51 | 24.0 | 2.96e-01 | 96.3% | 72.4% |
| 4uhiA01 | 1.10.630.10 | Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 | 0.51 | 41.0 | 2.85e-01 | 91.6% | 70.3% |
| 6l2cB00 | 3.40.47.10 | Alpha Beta › 3-Layer(aba) Sandwich › Peroxisomal Thiolase; Chain A, domain 1 › Thiolase/Chalcone synthase | 0.50 | 42.0 | 2.95e-01 | 95.3% | 84.2% |
| 2e5kA01 | 2.30.30.40 | Mainly Beta › Roll › SH3 type barrels. › SH3 Domains | 0.50 | 24.0 | 3.01e-01 | 93.5% | 73.4% |
D5
medium
residues 583-687
Domain cluster:
rep: VP1_RNA-dependent_RNA_polymerase__NP_690839__Infectious_bursal_disease_virus__10995__D603-698
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF20488.4 best | Birna_VP1_thumb | 170.5 | 3.90e-50 | 100.0% | 63.5% |