Back to structures

VP2

Euk-Vir

American_grass_carp_reovirus

VP2__YP_001837095__American_grass_carp_reovirus__465447

Identity

Accession:
YP_001837095 ↗
Protein ID:
VP2
Kingdom:
euk

Quality

89.0 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 966-1046_1125-1153
PDB
Domain cluster: representative
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF07925.16 best RdRP_5 133.6 7.60e-39 75.4% 6.5%
PF07925.16 RdRP_5 39.5 1.90e-10 30.0% 2.5%
CATH (4)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1e91A00 1.20.1160.11 Mainly Alpha › Up-down Bundle › Paired amphipathic helix 2 (pah2 repeat) › Paired amphipathic helix 0.58 39.0 4.30e-01 81.8% 88.2%
1jmwA00 1.20.120.30 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartate receptor, ligand-binding domain 0.56 42.0 3.86e-01 79.1% 61.0%
3pvuA02 1.10.167.10 Mainly Alpha › Orthogonal Bundle › Regulator of G-protein Signalling 4; domain 2 › Regulator of G-protein Signalling 4, domain 2 0.55 32.0 3.58e-01 74.5% 75.0%
2qgsB01 1.10.472.50 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › HD-domain/PDEase-like 0.51 36.0 3.97e-01 76.4% 92.0%
ECOD (8)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
1697853 4962.1.1.2 alpha complex topology › C-terminal additional helical subdomain in reovirus polymerase lambda3 › C-terminal additional helical subdomain in reovirus polymerase lambda3 › C-terminal additional helical subdomain in reovirus polymerase lambda3 › RdRP_5 0.92 85.0 5.59e-01 94.5% 48.5%
2392233 4962.1.1.2 alpha complex topology › C-terminal additional helical subdomain in reovirus polymerase lambda3 › C-terminal additional helical subdomain in reovirus polymerase lambda3 › C-terminal additional helical subdomain in reovirus polymerase lambda3 › RdRP_5 0.89 85.0 5.61e-01 100.0% 50.4%
3940361 108.1.1.0 alpha arrays › EF-hand › EF-hand-related › EF-hand 0.55 26.0 3.09e-01 86.4% 64.0%
1409242 132.1.1.2 alpha bundles › ACP-like › Acyl-carrier protein (ACP) › Acyl-carrier protein (ACP) › Ribosomal_L50 0.54 22.0 2.63e-01 77.3% 54.8%
3900696 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.54 38.0 3.34e-01 74.5% 89.4%
3164743 5059.1.1.1 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA 0.52 38.0 3.32e-01 74.5% 89.1%
4620518 191.1.1.0 alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain 0.50 34.0 3.42e-01 87.3% 68.2%
3805617 633.1.1.1 alpha bundles › Bromodomain-like › Bromodomain › Bromodomain › Bromodomain 0.50 39.0 3.52e-01 83.6% 72.3%
D2 medium residues 294-325_561-597_690-802
PDB
Pfam (3)
AccessionNameScoreE-valueQ covHMM cov
PF07925.16 best RdRP_5 237.8 2.70e-70 62.6% 8.9%
PF07925.16 RdRP_5 63.1 1.40e-17 22.5% 3.1%
PF07925.16 RdRP_5 46.7 1.30e-12 18.7% 2.6%
D3 medium residues 425-560_598-689
PDB
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF07925.16 best RdRP_5 277.7 2.30e-82 60.1% 10.7%
PF07925.16 RdRP_5 178.8 1.70e-52 40.8% 7.2%
D4 medium residues 803-881
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF07925.16 best RdRP_5 165.2 2.20e-48 100.0% 6.2%
D5 medium residues 898-965_1047-1057
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF07925.16 best RdRP_5 111.6 3.40e-32 97.5% 5.4%
CATH (3)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1or7B01 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.62 41.0 3.89e-01 73.4% 57.4%
5ch5A00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.53 45.0 2.76e-01 97.5% 83.6%
3rx6A00 1.20.58.1090 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phage polarity suppression protein monomer 0.50 38.0 2.94e-01 82.3% 46.5%
ECOD (4)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
2392233 4962.1.1.2 alpha complex topology › C-terminal additional helical subdomain in reovirus polymerase lambda3 › C-terminal additional helical subdomain in reovirus polymerase lambda3 › C-terminal additional helical subdomain in reovirus polymerase lambda3 › RdRP_5 0.97 93.0 5.72e-01 100.0% 42.4%
1697853 4962.1.1.2 alpha complex topology › C-terminal additional helical subdomain in reovirus polymerase lambda3 › C-terminal additional helical subdomain in reovirus polymerase lambda3 › C-terminal additional helical subdomain in reovirus polymerase lambda3 › RdRP_5 0.87 80.0 5.04e-01 100.0% 40.3%
3039404 4962.1.1.2 alpha complex topology › C-terminal additional helical subdomain in reovirus polymerase lambda3 › C-terminal additional helical subdomain in reovirus polymerase lambda3 › C-terminal additional helical subdomain in reovirus polymerase lambda3 › RdRP_5 0.84 67.0 7.17e-01 84.8% 100.0%
3742811 604.6.1.1 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › GAT 0.52 38.0 3.40e-01 97.5% 53.9%
D6 medium residues 1058-1114_1176-1274
PDB
Domain cluster: representative
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF07925.16 best RdRP_5 173.9 5.10e-51 64.1% 7.7%
PF07925.16 RdRP_5 90.0 1.10e-25 37.8% 4.5%
CATH (1)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2r7rA07 3.30.230.140 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › 0.72 53.0 5.94e-01 100.0% 99.2%
ECOD (2)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
2392233 4962.1.1.2 alpha complex topology › C-terminal additional helical subdomain in reovirus polymerase lambda3 › C-terminal additional helical subdomain in reovirus polymerase lambda3 › C-terminal additional helical subdomain in reovirus polymerase lambda3 › RdRP_5 0.98 96.0 6.84e-01 100.0% 57.6%
1697853 4962.1.1.2 alpha complex topology › C-terminal additional helical subdomain in reovirus polymerase lambda3 › C-terminal additional helical subdomain in reovirus polymerase lambda3 › C-terminal additional helical subdomain in reovirus polymerase lambda3 › RdRP_5 0.95 93.0 6.70e-01 100.0% 59.1%