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VP39

Euk-Vir

Murmansk_poxvirus

VP39__YP_009408273__Murmansk_poxvirus__2025359

Identity

Accession:
YP_009408273 ↗
Protein ID:
VP39
Kingdom:
euk

Quality

87.7 mean pLDDT

Cluster

View cluster (66 members)

3D Structure

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Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 1-302
PDB
Domain cluster: rep: poly-A-_polymerase_small_subunit_VP39__YP_008003925__Adoxophyes_honmai_entomopoxvirus_L__1293540__D16-287
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF01358.25 best PARP_regulatory 480.3 2.20e-144 96.7% 100.0%
CATH (40)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1eamA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 1.00 93.0 9.62e-01 98.3% 100.0%
2jhpA02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.75 56.0 5.80e-01 87.7% 79.9%
1iz0A02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.69 36.0 5.07e-01 84.4% 100.0%
4eyeA02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.67 36.0 4.96e-01 84.8% 100.0%
1o89A02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.64 37.0 4.85e-01 85.8% 100.0%
3lkdA02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.64 49.0 5.09e-01 77.5% 86.9%
1pvdA02 3.40.50.1220 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › TPP-binding domain 0.62 31.0 4.20e-01 88.1% 89.6%
3lmkA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.62 35.0 4.64e-01 76.5% 98.8%
2xciC01 3.40.50.11720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 3-Deoxy-D-manno-octulosonic-acid transferase, N-terminal domain 0.62 31.0 4.17e-01 76.2% 87.9%
1dbrC00 3.40.50.2020 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.61 36.0 4.17e-01 73.8% 79.5%
2ekdA00 3.40.50.11570 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Protein of unknown function DUF257 0.60 38.0 4.55e-01 85.8% 92.1%
2vbfA02 3.40.50.1220 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › TPP-binding domain 0.60 31.0 4.08e-01 87.4% 89.6%
2uz1A02 3.40.50.1220 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › TPP-binding domain 0.59 32.0 4.04e-01 79.8% 85.0%
3d3kA00 3.40.50.10260 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › YjeF N-terminal domain 0.59 44.0 4.93e-01 88.4% 98.3%
2cb0A02 3.40.50.10490 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 0.59 31.0 4.28e-01 81.1% 100.0%
1q6zA02 3.40.50.1220 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › TPP-binding domain 0.59 31.0 4.15e-01 80.1% 93.8%
3i3wA01 3.40.120.10 Alpha Beta › 3-Layer(aba) Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 3 › Alpha-D-Glucose-1,6-Bisphosphate, subunit A, domain 3 0.58 29.0 4.01e-01 87.1% 92.7%
2hf9B00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.58 33.0 3.91e-01 75.8% 78.5%
1ovmA02 3.40.50.1220 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › TPP-binding domain 0.58 30.0 4.04e-01 88.1% 94.2%
5x4kA01 3.90.1640.30 Alpha Beta › Alpha-Beta Complex › inorganic pyrophosphatase (n-terminal core) › 0.57 36.0 4.44e-01 97.4% 98.4%
2a3nA01 3.40.50.10490 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 0.57 32.0 4.16e-01 86.1% 98.1%
1j5xA02 3.40.50.10490 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 0.56 29.0 4.05e-01 87.1% 100.0%
1j5xA01 3.40.50.10490 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 0.56 30.0 4.09e-01 82.5% 100.0%
2gnpA00 3.40.50.1360 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.55 41.0 4.38e-01 75.5% 100.0%
5vogA00 3.40.50.2020 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.55 33.0 4.16e-01 91.4% 99.4%
1xv5A01 3.40.50.2000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; 0.54 34.0 4.21e-01 71.5% 97.9%
5agaA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.54 34.0 4.10e-01 76.2% 93.1%
1qzuA00 3.40.50.1950 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Flavin prenyltransferase-like 0.54 29.0 3.92e-01 70.9% 97.5%
2bkaA00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.54 40.0 4.52e-01 78.5% 98.7%
1vi6C01 3.40.50.10490 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 0.53 34.0 4.10e-01 96.7% 98.9%
2cb0A01 3.40.50.10490 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 0.53 29.0 3.89e-01 86.1% 100.0%
3s8mA00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.52 44.0 4.02e-01 86.8% 97.9%
6fwrA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.52 33.0 4.03e-01 70.2% 95.5%
3icoA00 3.40.50.1360 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.52 39.0 4.25e-01 75.5% 100.0%
2ayiA01 3.40.1830.10 Alpha Beta › 3-Layer(aba) Sandwich › Thermophilic metalloprotease-like › Thermophilic metalloprotease (M29) 0.52 31.0 3.86e-01 75.2% 97.1%
1o94A03 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.52 25.0 3.42e-01 77.8% 88.2%
3caiA02 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.51 39.0 4.19e-01 80.5% 90.3%
4icsA01 3.40.1830.10 Alpha Beta › 3-Layer(aba) Sandwich › Thermophilic metalloprotease-like › Thermophilic metalloprotease (M29) 0.51 31.0 3.81e-01 78.1% 95.1%
2gzaB02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.51 31.0 3.62e-01 84.8% 83.1%
3cr8C02 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.50 29.0 3.53e-01 85.4% 84.8%
ECOD (52)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
9332 2003.1.5.11 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › PARP_regulatory 0.99 95.0 9.69e-01 98.3% 100.0%
3599718 2003.1.5.11 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › PARP_regulatory 0.87 83.0 7.66e-01 97.7% 86.3%
3597302 2003.1.5.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases 0.84 79.0 7.81e-01 95.7% 99.0%
3717817 2003.1.5.11 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › PARP_regulatory 0.84 79.0 7.89e-01 96.0% 99.0%
3815647 2003.1.5.220 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › PF26055 0.71 44.0 4.77e-01 77.8% 71.3%
4031869 2003.1.1.5 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › ADH_zinc_N 0.67 38.0 4.94e-01 87.4% 94.9%
4288608 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.67 47.0 4.33e-01 70.5% 95.0%
4287265 2003.1.5.15 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › FtsJ 0.67 48.0 5.50e-01 72.2% 98.2%
4941471 2003.1.5.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases 0.66 47.0 4.97e-01 71.2% 89.3%
3955014 2003.1.5.41 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › RMNT_CmcI 0.66 46.0 5.23e-01 70.5% 93.2%
3728807 2003.1.1.5 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › ADH_zinc_N 0.66 39.0 4.86e-01 86.8% 92.1%
5056760 2003.1.5.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases 0.66 37.0 4.71e-01 78.5% 90.3%
4518850 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.65 46.0 3.96e-01 70.5% 79.7%
3719711 7512.1.1.0 ↗ a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase 0.63 31.0 4.27e-01 70.2% 92.0%
5024841 2006.1.1.1 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase 0.63 32.0 4.14e-01 87.4% 82.9%
4442161 2003.1.14.1 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › Aspartate/ornithine carbamoyltransferase › OTCace 0.62 37.0 4.58e-01 80.5% 91.6%
4001429 2003.1.7.10 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NagB/RpiA/CoA transferase-like › Rib_5-P_isom_A 0.62 34.0 4.55e-01 77.2% 98.8%
3349539 2003.1.5.31 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › GRAS 0.61 45.0 4.18e-01 73.8% 93.9%
4953711 2003.1.1.48 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › YjeF_N 0.61 44.0 5.09e-01 80.1% 98.2%
4608466 2003.1.5.71 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_33 0.61 43.0 4.17e-01 70.9% 80.9%
3921621 2003.1.5.359 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Spermine_synth, Methyltransf_25 0.60 51.0 3.92e-01 88.1% 51.8%
4290353 2003.1.1.48 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › YjeF_N 0.60 46.0 5.09e-01 85.4% 97.1%
3974744 2003.1.4.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › DHS-like NAD/FAD-binding domain 0.60 32.0 4.10e-01 87.7% 87.1%
4540341 2003.1.1.48 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › YjeF_N 0.60 45.0 5.00e-01 85.8% 95.1%
4428747 2003.1.1.48 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › YjeF_N 0.60 44.0 5.03e-01 81.8% 100.0%
5036272 2003.1.1.48 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › YjeF_N 0.60 42.0 4.89e-01 82.8% 98.2%
4146432 2003.1.1.20 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › Epimerase 0.59 42.0 4.67e-01 70.9% 100.0%
3729386 2003.1.1.67 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › NAD_binding_10 0.59 41.0 4.64e-01 70.2% 100.0%
4051226 2007.6.1.5 ↗ a/b three-layered sandwiches › Flavodoxin-like › Ribosomal protein S2/SIS domain › Ribosomal protein S2/SIS domain › bact-PGI_C 0.58 28.0 3.76e-01 80.5% 83.1%
4608168 2003.1.1.62 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › HIM1 0.58 41.0 4.62e-01 70.2% 100.0%
4586346 2003.1.1.48 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › YjeF_N 0.58 43.0 4.88e-01 82.5% 100.0%
3590339 2007.6.1.4 ↗ a/b three-layered sandwiches › Flavodoxin-like › Ribosomal protein S2/SIS domain › Ribosomal protein S2/SIS domain › SIS 0.58 34.0 4.36e-01 90.4% 99.4%
4154260 7512.1.1.15 ↗ a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyphos_transf 0.58 34.0 4.04e-01 79.1% 83.4%
4942613 2003.1.1.48 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › YjeF_N 0.57 42.0 4.80e-01 95.7% 99.6%
4260097 2003.1.1.143 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › NmrA, NAD_binding_10 0.57 44.0 4.32e-01 78.8% 99.1%
3688966 2003.1.1.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains 0.57 40.0 4.69e-01 74.8% 100.0%
4052456 2007.6.1.5 ↗ a/b three-layered sandwiches › Flavodoxin-like › Ribosomal protein S2/SIS domain › Ribosomal protein S2/SIS domain › bact-PGI_C 0.56 28.0 3.76e-01 80.8% 88.4%
3542046 2003.1.1.11 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › 3Beta_HSD 0.56 43.0 4.08e-01 79.1% 97.5%
None — 0.55 44.0 4.09e-01 79.8% 97.8%
3514944 7573.1.1.1 ↗ a/b three-layered sandwiches › PRTase-like › PRTase-like › PRTase-like › Pribosyltran 0.55 36.0 4.26e-01 93.7% 93.2%
3996219 2003.1.1.72 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › GDP_Man_Dehyd 0.55 44.0 4.20e-01 80.8% 93.8%
3796251 7577.1.1.3 ↗ a/b three-layered sandwiches › PLP-dependent transferases › PLP-dependent transferases › PLP-dependent transferases › Aminotran_5 0.55 36.0 4.27e-01 76.8% 94.8%
5064538 2007.6.1.5 ↗ a/b three-layered sandwiches › Flavodoxin-like › Ribosomal protein S2/SIS domain › Ribosomal protein S2/SIS domain › bact-PGI_C 0.54 27.0 3.67e-01 80.5% 90.9%
3538285 7512.1.1.0 ↗ a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase 0.54 35.0 4.04e-01 71.5% 87.5%
None — 0.54 42.0 4.10e-01 79.8% 98.8%
3682937 7512.1.1.31 ↗ a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_trans_4_4 0.53 36.0 4.14e-01 70.5% 91.4%
3989004 2004.1.1.42 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › T2SSE 0.53 35.0 3.48e-01 73.8% 61.6%
3395993 2003.1.5.26 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_28 0.53 45.0 4.09e-01 89.4% 74.8%
3811055 3698.1.1.2 ↗ beta sandwiches › Arginine methyltransferase oligomerization subdomain › Arginine methyltransferase oligomerization subdomain › Arginine methyltransferase oligomerization subdomain › PRMT_C 0.52 44.0 3.34e-01 87.7% 75.9%
3436963 7577.1.1.3 ↗ a/b three-layered sandwiches › PLP-dependent transferases › PLP-dependent transferases › PLP-dependent transferases › Aminotran_5 0.52 41.0 3.63e-01 86.4% 57.2%
1003758 298.1.1.0 ↗ a+b two layers › FwdE/GAPDH domain-like › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 0.52 42.0 3.61e-01 83.1% 91.3%
3725264 2003.1.1.67 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › NAD_binding_10 0.51 40.0 4.00e-01 80.5% 100.0%