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VP4
Euk-VirMobuck_virus
VP4__YP_008719907__Mobuck_virus__1408137
Identity
- Accession:
- YP_008719907 ↗
- Protein ID:
- VP4
- Kingdom:
- euk
Quality
93.4
mean pLDDT
Taxonomy
Orthornavirae›
Duplornaviricota›
Resentoviricetes›
Reovirales›
Sedoreoviridae›
Orbivirus›
Mobuck_virus
TaxID: 1408137
Cluster
View cluster (18 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 7-110
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF05059.21 best | Orbi_VP4 | 114.2 | 6.90e-33 | 100.0% | 16.0% |
CATH (60)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2px0A02 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.67 | 58.0 | 4.84e-01 | 96.2% | 96.2% |
| 2lciA00 | 3.40.50.11230 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.65 | 57.0 | 5.32e-01 | 100.0% | 90.3% |
| 4qqrB00 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.64 | 56.0 | 4.23e-01 | 100.0% | 72.4% |
| 5x2bD00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.63 | 55.0 | 4.15e-01 | 99.0% | 58.3% |
| 7bovA01 | 3.40.50.2000 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; | 0.63 | 55.0 | 4.59e-01 | 100.0% | 98.5% |
| 2x4gA00 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.63 | 55.0 | 4.05e-01 | 100.0% | 67.9% |
| 6yhrA01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.63 | 49.0 | 4.02e-01 | 83.7% | 59.3% |
| 1vecA00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.63 | 49.0 | 3.94e-01 | 83.7% | 54.9% |
| 3e8xA00 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.62 | 54.0 | 4.39e-01 | 100.0% | 89.7% |
| 5es6A01 | 3.40.50.170 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Formyl transferase, N-terminal domain | 0.61 | 53.0 | 4.46e-01 | 100.0% | 78.9% |
| 3wnvA01 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.61 | 53.0 | 4.86e-01 | 100.0% | 90.9% |
| 4w7sA01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.61 | 48.0 | 3.59e-01 | 85.6% | 54.1% |
| 6a6eA02 | 3.40.640.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) | 0.61 | 47.0 | 3.59e-01 | 84.6% | 59.8% |
| 5gvrA00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.60 | 46.0 | 3.64e-01 | 83.7% | 50.4% |
| 2i5iA00 | 3.20.20.370 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycoside hydrolase/deacetylase | 0.60 | 50.0 | 3.81e-01 | 93.3% | 97.7% |
| 1cjmA00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.60 | 52.0 | 4.14e-01 | 99.0% | 70.0% |
| 2x7jA03 | 3.40.50.970 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains | 0.59 | 51.0 | 4.10e-01 | 95.2% | 82.2% |
| 2w2kA02 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.59 | 43.0 | 3.52e-01 | 76.9% | 91.8% |
| 7xg9A01 | 3.20.20.220 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › | 0.59 | 46.0 | 3.42e-01 | 85.6% | 87.3% |
| 1qdlB00 | 3.40.50.880 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Class I glutamine amidotransferase (GATase) domain | 0.58 | 51.0 | 4.25e-01 | 100.0% | 98.5% |
| 4nv1E01 | 3.40.50.170 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Formyl transferase, N-terminal domain | 0.58 | 50.0 | 4.28e-01 | 100.0% | 91.4% |
| 1u9jA01 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.58 | 51.0 | 3.97e-01 | 100.0% | 88.1% |
| 1k1eD00 | 3.40.50.1000 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like | 0.58 | 50.0 | 4.35e-01 | 99.0% | 88.8% |
| 1hkuA02 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.57 | 41.0 | 3.44e-01 | 76.9% | 93.3% |
| 3gzdA03 | 3.40.640.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) | 0.57 | 44.0 | 3.69e-01 | 84.6% | 88.1% |
| 2a3nA01 | 3.40.50.10490 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 | 0.57 | 50.0 | 4.38e-01 | 100.0% | 72.2% |
| 3vkjA00 | 3.20.20.70 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I | 0.57 | 49.0 | 3.46e-01 | 99.0% | 77.4% |
| 4xkjA01 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.56 | 48.0 | 4.51e-01 | 100.0% | 92.6% |
| 3sy8A01 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.56 | 49.0 | 4.52e-01 | 100.0% | 90.4% |
| 2zg5A02 | 3.40.640.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) | 0.56 | 49.0 | 3.93e-01 | 100.0% | 65.4% |
| 1ab5A00 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.56 | 48.0 | 4.59e-01 | 100.0% | 95.2% |
| 3hv2A00 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.56 | 48.0 | 4.50e-01 | 100.0% | 83.8% |
| 1vp4A02 | 3.40.640.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) | 0.56 | 46.0 | 3.65e-01 | 93.3% | 71.2% |
| 3lwsA01 | 3.40.640.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) | 0.55 | 44.0 | 3.39e-01 | 86.5% | 68.9% |
| 3uhjC01 | 3.40.50.1970 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.55 | 43.0 | 3.84e-01 | 84.6% | 77.6% |
| 1gpjA02 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.55 | 43.0 | 3.84e-01 | 85.6% | 81.2% |
| 6f2xA01 | 3.40.50.1000 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like | 0.55 | 47.0 | 4.24e-01 | 98.1% | 95.4% |
| 3phhA02 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.55 | 43.0 | 4.08e-01 | 86.5% | 90.0% |
| 3t6kA00 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.55 | 47.0 | 4.55e-01 | 100.0% | 96.7% |
| 1wlsA02 | 3.40.50.40 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.55 | 42.0 | 4.01e-01 | 85.6% | 90.8% |
| 3ndnA01 | 3.40.640.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) | 0.54 | 48.0 | 3.63e-01 | 100.0% | 51.4% |
| 4xa8A01 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.54 | 47.0 | 4.53e-01 | 100.0% | 94.1% |
| 1gm5A04 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.53 | 46.0 | 3.78e-01 | 96.2% | 60.3% |
| 3n53A00 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.53 | 46.0 | 4.47e-01 | 100.0% | 91.5% |
| 5cheA02 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.53 | 40.0 | 3.59e-01 | 81.7% | 98.0% |
| 3f6tA03 | 3.40.640.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) | 0.53 | 46.0 | 3.71e-01 | 100.0% | 77.3% |
| 3aawC01 | 3.40.1160.10 | Alpha Beta › 3-Layer(aba) Sandwich › Carbamate kinase › Acetylglutamate kinase-like | 0.53 | 46.0 | 3.66e-01 | 100.0% | 81.5% |
| 1y8qB01 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.53 | 46.0 | 3.69e-01 | 100.0% | 78.8% |
| 4v19F00 | 3.40.1370.10 | Alpha Beta › 3-Layer(aba) Sandwich › Ribosomal Protein L4; Chain: A; › Ribosomal protein L4/L1 | 0.53 | 40.0 | 3.13e-01 | 82.7% | 90.4% |
| 2zsjA02 | 3.40.50.1100 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.53 | 38.0 | 3.95e-01 | 76.9% | 90.7% |
| 4eukA00 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.53 | 45.0 | 4.21e-01 | 100.0% | 94.9% |
| 3qz6A00 | 3.20.20.60 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Phosphoenolpyruvate-binding domains | 0.52 | 44.0 | 3.36e-01 | 94.2% | 79.9% |
| 5nmxB02 | 3.50.50.60 | Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain | 0.52 | 40.0 | 4.16e-01 | 92.3% | 92.5% |
| 1p0kA00 | 3.20.20.70 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I | 0.52 | 45.0 | 3.33e-01 | 99.0% | 81.0% |
| 3p8kA00 | 3.60.110.10 | Alpha Beta › 4-Layer Sandwich › Nitrilase/N-carbamoyl-D-aminoacid amidohydrolase › Carbon-nitrogen hydrolase | 0.52 | 45.0 | 3.39e-01 | 98.1% | 88.1% |
| 3eyaH01 | 3.40.50.970 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains | 0.52 | 44.0 | 3.80e-01 | 99.0% | 89.9% |
| 1gzhD02 | 3.40.50.10190 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › BRCT domain | 0.52 | 40.0 | 3.89e-01 | 100.0% | 74.8% |
| 3kljA02 | 3.50.50.60 | Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain | 0.51 | 42.0 | 4.15e-01 | 90.4% | 91.8% |
| 2bhsB01 | 3.40.50.1100 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.51 | 41.0 | 3.55e-01 | 87.5% | 77.9% |
| 3ecaA02 | 3.40.50.40 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.50 | 39.0 | 3.82e-01 | 85.6% | 93.9% |
ECOD (47)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 185911 | 2004.7.1.1 ↗ | a/b three-layered sandwiches › P-loop domains-like › VP4 N-terminal domain › VP4 N-terminal domain › Orbi_VP4 | 0.94 | 89.0 | 8.72e-01 | 100.0% | 92.8% |
| None | — | 0.66 | 58.0 | 4.23e-01 | 100.0% | 64.5% | |
| 4097104 | 2003.1.1.53 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › NmrA | 0.66 | 58.0 | 4.23e-01 | 100.0% | 67.3% |
| 3714023 | 2004.1.1.29 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD | 0.65 | 51.0 | 3.70e-01 | 83.7% | 43.7% |
| 3260826 | 2003.1.1.0 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains | 0.64 | 56.0 | 4.70e-01 | 100.0% | 81.6% |
| 4162575 | 2004.1.1.29 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD | 0.64 | 49.0 | 3.70e-01 | 83.7% | 44.8% |
| 1726247 | 7571.1.1.1 ↗ | a/b three-layered sandwiches › Formyltransferase › Formyltransferase › Formyltransferase › Formyl_trans_N | 0.61 | 53.0 | 4.43e-01 | 100.0% | 76.9% |
| 3233844 | 2004.1.1.29 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD | 0.61 | 48.0 | 3.55e-01 | 84.6% | 54.2% |
| 4023832 | 2007.1.1.1 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Class I glutamine amidotransferase-like › GATase | 0.61 | 53.0 | 4.17e-01 | 99.0% | 96.1% |
| 5001302 | 2004.1.1.194 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C_2 | 0.61 | 54.0 | 4.29e-01 | 100.0% | 80.9% |
| 4926812 | 2004.1.1.30 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C | 0.60 | 47.0 | 3.68e-01 | 84.6% | 45.5% |
| 3257794 | 7515.1.1.0 ↗ | a/b three-layered sandwiches › Alkaline phosphatase-like › Alkaline phosphatase-like › Alkaline phosphatase-like | 0.60 | 53.0 | 3.96e-01 | 99.0% | 95.6% |
| 4027981 | 2004.1.1.29 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD | 0.60 | 47.0 | 3.53e-01 | 83.7% | 45.4% |
| 3739827 | 2004.1.1.30 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C | 0.60 | 50.0 | 3.83e-01 | 91.3% | 53.9% |
| 3973942 | 2004.1.1.129 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Zot | 0.60 | 49.0 | 3.99e-01 | 90.4% | 97.6% |
| 3181945 | 2004.1.1.30 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C | 0.60 | 49.0 | 3.63e-01 | 90.4% | 53.6% |
| 5023835 | 7574.1.1.0 ↗ | a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) | 0.59 | 50.0 | 4.35e-01 | 95.2% | 85.9% |
| 5018409 | 2007.1.1.1 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Class I glutamine amidotransferase-like › GATase | 0.59 | 51.0 | 4.10e-01 | 99.0% | 87.0% |
| 5054853 | 2004.1.1.194 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C_2 | 0.58 | 51.0 | 4.18e-01 | 100.0% | 75.1% |
| 3678022 | 2004.1.1.29 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD | 0.58 | 45.0 | 3.77e-01 | 84.6% | 60.0% |
| 3689915 | 109.4.1.1227 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › NPHP3_N | 0.58 | 44.0 | 2.80e-01 | 82.7% | 28.3% |
| 5009930 | 7592.1.1.6 ↗ | a/b three-layered sandwiches › CARF (CRISPR-associated Rossmann fold) domains › CARF (CRISPR-associated Rossmann fold) domains › CARF (CRISPR-associated Rossmann fold) domains › Csa3_N | 0.58 | 43.0 | 3.96e-01 | 78.8% | 97.8% |
| 3283419 | 2003.1.1.5 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › ADH_zinc_N | 0.58 | 46.0 | 4.12e-01 | 88.5% | 81.3% |
| 3671549 | 2007.1.1.1 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Class I glutamine amidotransferase-like › GATase | 0.57 | 50.0 | 3.94e-01 | 100.0% | 88.9% |
| 4143288 | 323.1.1.3 ↗ | a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding | 0.57 | 47.0 | 4.04e-01 | 91.3% | 61.7% |
| 3647942 | 2004.1.1.30 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C | 0.56 | 45.0 | 3.72e-01 | 89.4% | 73.2% |
| 3279985 | 323.1.1.3 ↗ | a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding | 0.56 | 36.0 | 3.27e-01 | 91.3% | 45.3% |
| 4990686 | 2003.1.2.0 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain | 0.56 | 40.0 | 3.31e-01 | 76.0% | 55.0% |
| 3933239 | 2004.1.1.30 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C | 0.56 | 50.0 | 4.29e-01 | 99.0% | 78.2% |
| 4483195 | 7591.1.1.1 ↗ | a/b three-layered sandwiches › Tetraacyldisaccharide 4'-kinase C-terminal domain › Tetraacyldisaccharide 4'-kinase C-terminal domain › Tetraacyldisaccharide 4'-kinase C-terminal domain › LpxK | 0.56 | 39.0 | 4.00e-01 | 82.7% | 76.0% |
| 3635837 | 3016.1.1.3 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › Aminotran_5 | 0.55 | 46.0 | 2.97e-01 | 92.3% | 34.2% |
| 3415335 | 2007.1.2.0 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I | 0.55 | 48.0 | 4.21e-01 | 96.2% | 98.1% |
| 4444459 | 2003.1.1.0 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains | 0.55 | 42.0 | 3.24e-01 | 85.6% | 49.8% |
| 4331470 | 2007.1.9.5 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE) › Exonuc_VII_L | 0.54 | 47.0 | 4.15e-01 | 100.0% | 75.8% |
| 5023361 | 2007.1.3.0 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like | 0.54 | 47.0 | 4.14e-01 | 100.0% | 73.1% |
| 4029114 | 2006.1.3.11 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › TOP6A-Spo11_Toprim | 0.54 | 46.0 | 3.96e-01 | 99.0% | 97.8% |
| 4389445 | 2002.3.1.6 ↗ | a/b barrels › TIM beta/alpha-barrel › Glycoside hydrolase/deacetylase › Glycoside hydrolase/deacetylase › YdjC | 0.54 | 44.0 | 3.41e-01 | 91.3% | 98.8% |
| 3960389 | 2003.1.1.0 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains | 0.53 | 43.0 | 3.70e-01 | 88.5% | 82.9% |
| 4024926 | 2006.1.3.11 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › TOP6A-Spo11_Toprim | 0.53 | 45.0 | 4.03e-01 | 99.0% | 97.5% |
| 234921 | 2007.1.3.1 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg | 0.53 | 45.0 | 4.21e-01 | 100.0% | 94.9% |
| 4455739 | 2007.1.12.2 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Type II 3-dehydroquinate dehydratase › Exonuc_VII_L | 0.53 | 43.0 | 3.17e-01 | 93.3% | 40.9% |
| 3174356 | 2006.1.3.11 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › TOP6A-Spo11_Toprim | 0.52 | 43.0 | 3.78e-01 | 94.2% | 98.2% |
| 3726355 | 7573.1.1.4 ↗ | a/b three-layered sandwiches › PRTase-like › PRTase-like › PRTase-like › UPRTase | 0.52 | 38.0 | 3.20e-01 | 77.9% | 83.7% |
| 2029628 | 7597.1.1.1 ↗ | a/b three-layered sandwiches › Endolysin C-terminal domain › Endolysin C-terminal domain › Endolysin C-terminal domain › CW_binding_2 | 0.52 | 41.0 | 4.26e-01 | 96.2% | 94.9% |
| 3421413 | 207.1.1.0 ↗ | beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats | 0.52 | 38.0 | 3.91e-01 | 83.7% | 81.0% |
| 4625701 | 2003.1.1.24 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › Shikimate_DH | 0.51 | 39.0 | 3.64e-01 | 84.6% | 85.7% |
| 5037032 | 7577.1.1.1 ↗ | a/b three-layered sandwiches › PLP-dependent transferases › PLP-dependent transferases › PLP-dependent transferases › Aminotran_1_2 | 0.51 | 44.0 | 3.44e-01 | 100.0% | 51.6% |
D2
high
residues 179-393
Domain cluster:
rep: polyA_polymerase_reg_subunit__YP_009001345__Pithovirus_sibericum__1450746__D33-211
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF05059.21 best | Orbi_VP4 | 291.5 | 1.50e-86 | 100.0% | 33.7% |
D3
medium
residues 111-178_394-508
Domain cluster:
rep: VP3__YP_008136241__Rotavirus_G_chicken_03V0567_DEU_2003__994995__D197-250_406-523
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF05059.21 best | Orbi_VP4 | 141.0 | 5.30e-41 | 63.4% | 17.7% |
| PF05059.21 | Orbi_VP4 | 69.7 | 2.10e-19 | 37.7% | 10.6% |
CATH (42)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2hx1A02 | 3.40.50.1000 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like | 0.62 | 41.0 | 4.92e-01 | 89.6% | 100.0% |
| 3hueA03 | 3.40.50.11080 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.61 | 24.0 | 3.31e-01 | 97.8% | 69.6% |
| 1rjgA00 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.60 | 55.0 | 4.71e-01 | 100.0% | 75.9% |
| 1dhiA00 | 3.40.430.10 | Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A | 0.59 | 44.0 | 4.63e-01 | 99.5% | 87.4% |
| 3hnrA00 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.59 | 55.0 | 5.39e-01 | 100.0% | 95.3% |
| 3ftdA01 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.58 | 51.0 | 5.19e-01 | 100.0% | 95.5% |
| 3ry7A00 | 3.40.1190.20 | Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase | 0.57 | 46.0 | 3.86e-01 | 83.6% | 94.1% |
| 4hjhA03 | 3.40.120.10 | Alpha Beta › 3-Layer(aba) Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 3 › Alpha-D-Glucose-1,6-Bisphosphate, subunit A, domain 3 | 0.57 | 35.0 | 4.30e-01 | 92.3% | 95.7% |
| 2fp4A01 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.57 | 38.0 | 4.51e-01 | 90.7% | 99.2% |
| 3fkdA02 | 3.40.640.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) | 0.57 | 48.0 | 4.55e-01 | 92.9% | 76.2% |
| 6hxqA01 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.57 | 38.0 | 4.48e-01 | 90.7% | 96.9% |
| 1qyrA01 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.56 | 51.0 | 5.13e-01 | 100.0% | 96.2% |
| 1iayA02 | 3.40.640.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) | 0.56 | 49.0 | 4.45e-01 | 94.0% | 78.4% |
| 3sm3A00 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.56 | 51.0 | 4.87e-01 | 97.8% | 98.6% |
| 1lc5A02 | 3.40.640.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) | 0.56 | 49.0 | 4.60e-01 | 94.0% | 78.2% |
| 6mroA00 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.56 | 51.0 | 5.06e-01 | 99.5% | 92.8% |
| 5x7fA00 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.56 | 52.0 | 5.13e-01 | 100.0% | 98.0% |
| 4pwyA00 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.56 | 52.0 | 4.65e-01 | 100.0% | 96.8% |
| 7pthC01 | 3.40.720.10 | Alpha Beta › 3-Layer(aba) Sandwich › Alkaline Phosphatase, subunit A › Alkaline Phosphatase, subunit A | 0.56 | 49.0 | 3.66e-01 | 95.1% | 71.1% |
| 3ffhB02 | 3.40.640.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) | 0.55 | 48.0 | 4.59e-01 | 92.9% | 82.9% |
| 2vycA02 | 3.40.640.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) | 0.55 | 49.0 | 4.15e-01 | 96.2% | 69.8% |
| 5dj1A02 | 3.40.640.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) | 0.55 | 48.0 | 4.46e-01 | 95.1% | 74.9% |
| 6qp2A01 | 3.40.640.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) | 0.55 | 48.0 | 4.41e-01 | 93.4% | 77.8% |
| 2h0aA01 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.54 | 28.0 | 3.48e-01 | 99.5% | 77.7% |
| 2o3jB01 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.54 | 45.0 | 4.29e-01 | 87.4% | 100.0% |
| 3n5mA02 | 3.40.640.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) | 0.54 | 47.0 | 4.14e-01 | 94.5% | 80.3% |
| 3ftbA02 | 3.40.640.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) | 0.54 | 47.0 | 4.43e-01 | 94.0% | 97.3% |
| 3qtgA03 | 3.40.1380.20 | Alpha Beta › 3-Layer(aba) Sandwich › Pyruvate Kinase; Chain: A, domain 1 › Pyruvate kinase, C-terminal domain | 0.53 | 32.0 | 3.87e-01 | 99.5% | 92.2% |
| 4q6bA02 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.53 | 38.0 | 4.28e-01 | 96.2% | 98.5% |
| 2x7jA03 | 3.40.50.970 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains | 0.53 | 47.0 | 4.56e-01 | 95.1% | 87.6% |
| 6yhrA01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.53 | 41.0 | 4.08e-01 | 98.4% | 77.8% |
| 2z67A00 | 3.40.640.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) | 0.53 | 46.0 | 3.50e-01 | 94.0% | 42.0% |
| 7lldA01 | 3.40.640.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) | 0.52 | 47.0 | 4.28e-01 | 96.2% | 74.4% |
| 3hwwA01 | 3.40.50.970 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains | 0.52 | 49.0 | 4.70e-01 | 100.0% | 99.0% |
| 4wbxC01 | 3.40.50.970 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains | 0.52 | 47.0 | 4.71e-01 | 97.3% | 93.2% |
| 2e7jA02 | 3.40.640.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) | 0.52 | 46.0 | 4.24e-01 | 94.5% | 79.3% |
| 3nx3A02 | 3.40.640.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) | 0.52 | 46.0 | 4.19e-01 | 96.2% | 79.4% |
| 3bosB01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.52 | 38.0 | 4.07e-01 | 94.5% | 86.4% |
| 3i4jB02 | 3.40.640.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) | 0.51 | 45.0 | 4.04e-01 | 94.0% | 77.5% |
| 1a3cA00 | 3.40.50.2020 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.51 | 37.0 | 3.92e-01 | 96.7% | 81.9% |
| 2zvbA02 | 3.30.950.10 | Alpha Beta › 2-Layer Sandwich › Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 › Tetrapyrrole methylase, C-terminal domain | 0.51 | 33.0 | 3.80e-01 | 96.2% | 90.6% |
| 2xdqA02 | 3.40.50.1980 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nitrogenase molybdenum iron protein domain | 0.50 | 36.0 | 4.05e-01 | 97.3% | 97.8% |
ECOD (46)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4988836 | 2003.1.5.66 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 | 0.67 | 54.0 | 5.78e-01 | 100.0% | 98.7% |
| 3700367 | 2003.1.5.26 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_28 | 0.67 | 62.0 | 4.66e-01 | 100.0% | 79.5% |
| 4992057 | 2003.1.1.0 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains | 0.62 | 41.0 | 4.88e-01 | 92.3% | 100.0% |
| 4025300 | 2003.1.5.79 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_23 | 0.62 | 56.0 | 5.36e-01 | 98.4% | 93.0% |
| 3955206 | 2003.1.5.0 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases | 0.61 | 56.0 | 5.13e-01 | 99.5% | 100.0% |
| 4044555 | 2003.1.5.151 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_23, Methyltransf_25 | 0.59 | 55.0 | 5.31e-01 | 99.5% | 88.8% |
| 5023411 | 2003.1.1.0 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains | 0.59 | 42.0 | 4.67e-01 | 98.4% | 94.3% |
| 3600251 | 2003.1.5.0 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases | 0.59 | 54.0 | 4.36e-01 | 100.0% | 88.3% |
| 5019368 | 2003.1.5.66 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 | 0.59 | 54.0 | 5.10e-01 | 100.0% | 89.1% |
| 5006335 | 2004.1.1.1200 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DUF835 | 0.58 | 40.0 | 4.48e-01 | 79.8% | 89.0% |
| 4248688 | 7577.1.1.1 ↗ | a/b three-layered sandwiches › PLP-dependent transferases › PLP-dependent transferases › PLP-dependent transferases › Aminotran_1_2 | 0.58 | 50.0 | 3.97e-01 | 93.4% | 66.7% |
| 5054899 | 7574.1.1.4 ↗ | a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › POR_N | 0.58 | 49.0 | 4.66e-01 | 93.4% | 75.8% |
| 4943805 | 2003.1.1.369 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › Ligase_CoA | 0.58 | 39.0 | 4.59e-01 | 90.7% | 98.4% |
| 4020104 | 2003.1.5.0 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases | 0.58 | 53.0 | 4.21e-01 | 100.0% | 79.5% |
| 4013371 | 2003.1.1.0 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains | 0.58 | 38.0 | 4.52e-01 | 90.7% | 97.6% |
| 5029352 | 3110.1.1.0 ↗ | a/b three-layered sandwiches › STT3/PglB/AglB core domain › STT3/PglB/AglB core domain › STT3/PglB/AglB core domain | 0.57 | 39.0 | 4.50e-01 | 98.4% | 100.0% |
| 3388813 | 2006.1.1.0 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like | 0.56 | 39.0 | 4.54e-01 | 94.0% | 100.0% |
| 3516621 | 2006.1.1.0 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like | 0.56 | 41.0 | 4.62e-01 | 94.0% | 100.0% |
| 4179980 | 2003.1.5.182 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › RrnaAD, Methyltransf_11 | 0.55 | 51.0 | 4.98e-01 | 100.0% | 92.3% |
| 1842810 | 7574.1.1.7 ↗ | a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › TPP_enzyme_N | 0.55 | 42.0 | 4.26e-01 | 100.0% | 80.2% |
| 3933637 | 2006.1.1.0 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like | 0.55 | 40.0 | 4.52e-01 | 93.4% | 98.6% |
| 4283804 | 7577.1.1.1 ↗ | a/b three-layered sandwiches › PLP-dependent transferases › PLP-dependent transferases › PLP-dependent transferases › Aminotran_1_2 | 0.55 | 48.0 | 3.87e-01 | 94.0% | 57.1% |
| 3959323 | 2003.1.1.31 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › CbiJ | 0.55 | 34.0 | 4.06e-01 | 91.3% | 93.3% |
| 4857488 | 7577.1.1.1 ↗ | a/b three-layered sandwiches › PLP-dependent transferases › PLP-dependent transferases › PLP-dependent transferases › Aminotran_1_2 | 0.55 | 48.0 | 4.24e-01 | 94.5% | 68.2% |
| 4027578 | 7577.1.1.13 ↗ | a/b three-layered sandwiches › PLP-dependent transferases › PLP-dependent transferases › PLP-dependent transferases › SepSecS | 0.55 | 48.0 | 3.85e-01 | 94.0% | 52.3% |
| 3955178 | 2003.1.5.42 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_21 | 0.55 | 51.0 | 4.72e-01 | 100.0% | 98.2% |
| 3398461 | 2006.1.1.0 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like | 0.54 | 38.0 | 4.37e-01 | 92.9% | 100.0% |
| 3603492 | 2003.1.5.55 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › PrmA | 0.54 | 50.0 | 4.73e-01 | 100.0% | 94.4% |
| 3524329 | 2006.1.1.0 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like | 0.54 | 42.0 | 4.42e-01 | 90.7% | 93.1% |
| None | — | 0.54 | 50.0 | 3.87e-01 | 100.0% | 86.7% | |
| 5019378 | 7574.1.1.5 ↗ | a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › TPP_enzyme_C | 0.54 | 49.0 | 3.75e-01 | 98.4% | 52.2% |
| 5056760 | 2003.1.5.0 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases | 0.53 | 47.0 | 4.72e-01 | 97.3% | 94.1% |
| 4238501 | 3016.1.1.2 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › Aminotran_3 | 0.53 | 46.0 | 3.53e-01 | 94.0% | 57.7% |
| 4955376 | 7577.1.1.10 ↗ | a/b three-layered sandwiches › PLP-dependent transferases › PLP-dependent transferases › PLP-dependent transferases › GDC-P | 0.53 | 47.0 | 3.76e-01 | 95.6% | 74.0% |
| 4931883 | 7574.1.1.5 ↗ | a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › TPP_enzyme_C | 0.53 | 47.0 | 4.75e-01 | 96.7% | 98.9% |
| 2588641 | 7577.1.1.1 ↗ | a/b three-layered sandwiches › PLP-dependent transferases › PLP-dependent transferases › PLP-dependent transferases › Aminotran_1_2 | 0.53 | 46.0 | 3.97e-01 | 95.6% | 81.5% |
| 3741050 | 2007.1.16.1 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Iron-sulphur enzyme Dph2 › Diphthamide_syn | 0.52 | 35.0 | 4.08e-01 | 98.4% | 99.2% |
| 3670409 | 7574.1.1.5 ↗ | a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › TPP_enzyme_C | 0.52 | 46.0 | 4.30e-01 | 96.7% | 86.5% |
| 3688213 | 2003.1.7.3 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NagB/RpiA/CoA transferase-like › CoA_trans | 0.52 | 45.0 | 4.12e-01 | 96.2% | 84.4% |
| 3459739 | 7518.1.1.1 ↗ | a/b three-layered sandwiches › PK C-terminal domain-like › PK C-terminal domain-like › PK C-terminal domain-like › PK_C | 0.51 | 34.0 | 3.79e-01 | 100.0% | 84.1% |
| 3285520 | 323.1.1.3 ↗ | a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding | 0.51 | 32.0 | 3.29e-01 | 92.3% | 64.6% |
| 3939199 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.51 | 37.0 | 3.86e-01 | 96.7% | 81.8% |
| None | — | 0.51 | 45.0 | 3.92e-01 | 97.3% | 71.9% | |
| 3728135 | 7574.1.1.7 ↗ | a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › TPP_enzyme_N | 0.51 | 46.0 | 4.50e-01 | 98.9% | 98.5% |
| 3688813 | 7574.1.1.7 ↗ | a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › TPP_enzyme_N | 0.50 | 45.0 | 4.44e-01 | 97.8% | 95.0% |
| 3988696 | 7577.1.1.6 ↗ | a/b three-layered sandwiches › PLP-dependent transferases › PLP-dependent transferases › PLP-dependent transferases › DegT_DnrJ_EryC1 | 0.50 | 44.0 | 3.83e-01 | 94.5% | 76.8% |
D4
medium
residues 509-646
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF05059.21 best | Orbi_VP4 | 202.1 | 1.70e-59 | 97.8% | 20.8% |
CATH (6)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3beeA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.63 | 35.0 | 4.18e-01 | 94.9% | 80.2% |
| 2vkjA00 | 1.20.58.2030 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.58 | 31.0 | 3.48e-01 | 95.7% | 65.1% |
| 4e4tB01 | 3.40.50.20 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.55 | 32.0 | 3.51e-01 | 82.6% | 69.0% |
| 3k9iA01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.55 | 29.0 | 3.30e-01 | 94.9% | 66.0% |
| 1oxjA02 | 1.25.40.170 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Smaug, PHAT domain | 0.52 | 35.0 | 3.94e-01 | 95.7% | 88.1% |
| 2o36A01 | 1.20.1050.40 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › Endopeptidase. Chain P; domain 1 | 0.51 | 32.0 | 3.30e-01 | 84.8% | 64.8% |
ECOD (6)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3164633 | 109.4.1.924 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_CcmH_CycH | 0.67 | 36.0 | 3.12e-01 | 93.5% | 34.8% |
| 4029405 | 109.4.1.584 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fis1_TPR_C | 0.66 | 37.0 | 3.76e-01 | 99.3% | 53.6% |
| 4056493 | 109.4.1.341 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_21 | 0.61 | 33.0 | 3.01e-01 | 94.2% | 37.8% |
| 3966838 | 109.4.1.341 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_21 | 0.60 | 32.0 | 2.81e-01 | 96.4% | 33.3% |
| 2140318 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.52 | 34.0 | 3.74e-01 | 88.4% | 82.7% |
| 3440159 | 130.1.1.0 ↗ | alpha arrays › LEM/SAP HeH motif-like › LEM/SAP HeH motif › LEM/SAP HeH motif | 0.51 | 22.0 | 2.73e-01 | 74.6% | 61.2% |